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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12678919
log Bayes Factor = 1.74917
Chromosome 8   position 19,844,222  (GRCh37) Explore rs12678919 on Ensembl!
Variant rs12678919 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.032 0.968
I25 Chronic ischaemic heart disease
0.000 0.038 0.962
I20-I25 Ischaemic heart diseases
0.000 0.041 0.959
I21 Acute myocardial infarction
0.000 0.071 0.929
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.086 0.914
I20 Angina pectoris
0.000 0.091 0.909
I24 Other acute ischaemic heart diseases
0.000 0.096 0.904
I20.9 Angina pectoris, unspecified
0.000 0.135 0.865
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.157 0.843
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.189 0.811
I22 Subsequent myocardial infarction
0.000 0.192 0.808
I21.9 Acute myocardial infarction, unspecified
0.000 0.193 0.807
I20.0 Unstable angina
0.000 0.206 0.794
I25.4 Coronary artery aneurysm
0.000 0.218 0.782
I25.2 Old myocardial infarction
0.000 0.236 0.764
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.237 0.763
I24.8 Other forms of acute ischaemic heart disease
0.000 0.246 0.754
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.281 0.719
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.302 0.698
I25.6 Silent myocardial ischaemia
0.000 0.310 0.690
I23 Certain current complications following acute myocardial infarction
0.000 0.312 0.688
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.317 0.683
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.334 0.666
I24.1 Dressler's syndrome
0.000 0.352 0.648
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.374 0.626
I20.8 Other forms of angina pectoris
0.000 0.391 0.609
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.398 0.602
I22.8 Subsequent myocardial infarction of other sites
0.000 0.421 0.579
I25.5 Ischaemic cardiomyopathy
0.000 0.426 0.574
I25.3 Aneurysm of heart
0.000 0.459 0.541
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.477 0.523
I20.1 Angina pectoris with documented spasm
0.000 0.488 0.512
I23.8 Other current complications following acute myocardial infarction
0.000 0.507 0.493
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.507 0.493
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.507 0.493
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.507 0.493
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.507 0.493
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.507 0.493
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.507 0.493
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.507 0.493
E78.0 Pure hypercholesterolaemia
0.000 0.532 0.468
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.538 0.462
E78.5 Hyperlipidaemia, unspecified
0.000 0.542 0.458
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.562 0.438
E78.2 Mixed hyperlipidaemia
0.000 0.593 0.407
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.618 0.382
E78.4 Other hyperlipidaemia
0.000 0.660 0.340
I21.4 Acute subendocardial myocardial infarction
0.000 0.662 0.337
E78.6 Lipoprotein deficiency
0.000 0.668 0.332
E78.3 Hyperchylomicronaemia
0.000 0.668 0.332
E78.1 Pure hyperglyceridaemia
0.000 0.668 0.332
E78.8 Other disorders of lipoprotein metabolism
0.000 0.684 0.316
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.862 0.138
E70-E90 Metabolic disorders
0.000 0.960 0.040
E73 Lactose intolerance
0.000 0.969 0.031
E83.1 Disorders of iron metabolism
0.000 0.969 0.031
E83 Disorders of mineral metabolism
0.000 0.970 0.030
E74 Other disorders of carbohydrate metabolism
0.000 0.971 0.029
E84 Cystic fibrosis
0.000 0.971 0.028
E79 Disorders of purine and pyrimidine metabolism
0.000 0.971 0.028
E77 Disorders of glycoprotein metabolism
0.000 0.971 0.028
E76 Disorders of glycosaminoglycan metabolism
0.000 0.971 0.028
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.971 0.028
E72 Other disorders of amino-acid metabolism
0.000 0.971 0.028
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.971 0.028
E70 Disorders of aromatic amino-acid metabolism
0.000 0.971 0.028
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.971 0.028
E88 Other metabolic disorders
0.000 0.972 0.028
E86 Volume depletion
0.000 0.973 0.027
E85 Amyloidosis
0.000 0.974 0.026
E73.9 Lactose intolerance, unspecified
0.000 0.975 0.025
E73.8 Other lactose intolerance
0.000 0.977 0.023
E73.1 Secondary lactase deficiency
0.000 0.977 0.023
E73.0 Congenital lactase deficiency
0.000 0.977 0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.978 0.022
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.978 0.022
E83.8 Other disorders of mineral metabolism
0.000 0.978 0.022
E83.2 Disorders of zinc metabolism
0.000 0.978 0.022
E83.0 Disorders of copper metabolism
0.000 0.978 0.022
E83.4 Disorders of magnesium metabolism
0.000 0.978 0.022
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.979 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.979 0.021
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.979 0.021
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.979 0.021
E74.2 Disorders of galactose metabolism
0.000 0.979 0.021
E74.1 Disorders of fructose metabolism
0.000 0.979 0.021
E74.0 Glycogen storage disease
0.000 0.979 0.021
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.979 0.021
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.979 0.021
E70.3 Albinism
0.000 0.979 0.021
E70.2 Disorders of tyrosine metabolism
0.000 0.979 0.021
E70.1 Other hyperphenylalaninaemias
0.000 0.979 0.021
E70.0 Classical phenylketonuria
0.000 0.979 0.021
E71.3 Disorders of fatty-acid metabolism
0.000 0.979 0.021
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.979 0.021
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.979 0.021
E71.0 Maple-syrup-urine disease
0.000 0.979 0.021
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.979 0.021
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.979 0.021
E72.5 Disorders of glycine metabolism
0.000 0.979 0.021
E72.4 Disorders of ornithine metabolism
0.000 0.979 0.021
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.979 0.021
E72.2 Disorders of urea cycle metabolism
0.000 0.979 0.021
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.979 0.021
E72.0 Disorders of amino-acid transport
0.000 0.979 0.021
E75.6 Lipid storage disorder, unspecified
0.000 0.979 0.021
E75.5 Other lipid storage disorders
0.000 0.979 0.021
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.979 0.021
E75.3 Sphingolipidosis, unspecified
0.000 0.979 0.021
E75.2 Other sphingolipidosis
0.000 0.979 0.021
E75.1 Other gangliosidosis
0.000 0.979 0.021
E75.0 GM2 gangliosidosis
0.000 0.979 0.021
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.979 0.021
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.979 0.021
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.979 0.021
E76.2 Other mucopolysaccharidoses
0.000 0.979 0.021
E76.1 Mucopolysaccharidosis, type II
0.000 0.979 0.021
E76.0 Mucopolysaccharidosis, type I
0.000 0.979 0.021
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.979 0.021
E77.8 Other disorders of glycoprotein metabolism
0.000 0.979 0.021
E77.1 Defects in glycoprotein degradation
0.000 0.979 0.021
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.979 0.021
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.979 0.021
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.979 0.021
E79.1 Lesch-Nyhan syndrome
0.000 0.979 0.021
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.979 0.021
E84.9 Cystic fibrosis, unspecified
0.000 0.979 0.021
E84.8 Cystic fibrosis with other manifestations
0.000 0.979 0.021
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.979 0.021
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.979 0.021
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.980 0.020
E88.9 Metabolic disorder, unspecified
0.000 0.980 0.020
E88.8 Other specified metabolic disorders
0.000 0.980 0.020
E88.3 Tumour lysis syndrome
0.000 0.980 0.020
E88.2 Lipomatosis, not elsewhere classified
0.000 0.980 0.020
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.980 0.020
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.981 0.019
E85.4 Organ-limited amyloidosis
0.000 0.981 0.019
E85.8 Other amyloidosis
0.000 0.981 0.019
E85.3 Secondary systemic amyloidosis
0.000 0.981 0.019
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.981 0.019
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.981 0.019
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.984 0.016
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.984 0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.984 0.016
E89.5 Postprocedural testicular hypofunction
0.000 0.984 0.016
E89.4 Postprocedural ovarian failure
0.000 0.984 0.016
E89.1 Postprocedural hypoinsulinaemia
0.000 0.984 0.016
E89.3 Postprocedural hypopituitarism
0.000 0.984 0.016
E85.9 Amyloidosis, unspecified
0.000 0.984 0.015
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.015
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.015
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.015
E80.2 Other porphyria
0.000 0.985 0.015
E80.1 Porphyria cutanea tarda
0.000 0.985 0.015
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.015
I77 Other disorders of arteries and arterioles
0.000 0.986 0.014
E83.3 Disorders of phosphorus metabolism
0.000 0.986 0.014
I77.6 Arteritis, unspecified
0.000 0.987 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.987 0.013
I77.1 Stricture of artery
0.000 0.987 0.013
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.987 0.013
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.988 0.012
I77.8 Other specified disorders of arteries and arterioles
0.000 0.988 0.012
I71 Aortic aneurysm and dissection
0.000 0.989 0.011
I70 Atherosclerosis
0.000 0.989 0.011
N39.4 Other specified urinary incontinence
0.000 0.989 0.011
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.989 0.010
I77.5 Necrosis of artery
0.000 0.990 0.010
I77.4 Coeliac artery compression syndrome
0.000 0.990 0.010
I77.3 Arterial fibromuscular dysplasia
0.000 0.990 0.010
I77.2 Rupture of artery
0.000 0.990 0.010
Chapter IX Diseases of the circulatory system
0.000 0.990 0.010
E80.4 Gilbert's syndrome
0.000 0.990 0.010
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.990 0.010
R16.1 Splenomegaly, not elsewhere classified
0.010 0.990 0.000
I72 Other aneurysm
0.000 0.990 0.010
I77.0 Arteriovenous fistula, acquired
0.000 0.990 0.009
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.991 0.009
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.991 0.009
I70.0 Atherosclerosis of aorta
0.000 0.991 0.009
I78 Diseases of capillaries
0.000 0.991 0.009
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.991 0.009
I72.4 Aneurysm of artery of lower extremity
0.000 0.991 0.009
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.992 0.008
I71.0 Dissection of aorta [any part]
0.000 0.992 0.008
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.992 0.008
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.992 0.008
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.992 0.008
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.992 0.008
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.992 0.008
I72.3 Aneurysm of iliac artery
0.000 0.992 0.008
I70.9 Generalised and unspecified atherosclerosis
0.000 0.992 0.008
I70.8 Atherosclerosis of other arteries
0.000 0.992 0.008
I70.1 Atherosclerosis of renal artery
0.000 0.992 0.008
I74 Arterial embolism and thrombosis
0.000 0.992 0.008
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.992 0.008
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.992 0.008
I79.1 Aortitis in diseases classified elsewhere
0.000 0.992 0.008
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.992 0.008
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.992 0.008
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.993 0.007
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.993 0.007
I00-I02 Acute rheumatic fever
0.000 0.993 0.007
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.007 0.993 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.993 0.007
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.993 0.007
I72.1 Aneurysm of artery of upper extremity
0.000 0.993 0.007
I72.8 Aneurysm of other specified arteries
0.000 0.993 0.007
I72.2 Aneurysm of renal artery
0.000 0.993 0.007
I72.9 Aneurysm of unspecified site
0.000 0.993 0.007
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.993 0.006
I78.9 Disease of capillaries, unspecified
0.000 0.993 0.007
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.993 0.006
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.993 0.007
I78.8 Other diseases of capillaries
0.000 0.994 0.006
E89.0 Postprocedural hypothyroidism
0.000 0.994 0.006
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.994 0.006
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.994 0.006
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.994 0.006
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.994 0.006
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.994 0.006
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.994 0.006
I74.5 Embolism and thrombosis of iliac artery
0.000 0.994 0.006
I74.8 Embolism and thrombosis of other arteries
0.000 0.994 0.006
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.994 0.006
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.994 0.006
I02 Rheumatic chorea
0.000 0.994 0.005
I01 Rheumatic fever with heart involvement
0.000 0.994 0.005
I00 Rheumatic fever without mention of heart involvement
0.000 0.994 0.005
I72.0 Aneurysm of carotid artery
0.000 0.994 0.005
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.995 0.005
I26 Pulmonary embolism
0.004 0.995 0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.995 0.005
K91.4 Colostomy and enterostomy malfunction
0.000 0.995 0.005
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.995 0.005
I51.9 Heart disease, unspecified
0.000 0.995 0.005
M20.1 Hallux valgus (acquired)
0.000 0.995 0.005
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.995 0.005
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.995 0.004
I73 Other peripheral vascular diseases
0.000 0.995 0.005
I97.1 Other functional disturbances following cardiac surgery
0.000 0.995 0.005
I78.1 Naevus, nonneoplastic
0.000 0.995 0.005
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.995 0.004
K62.0 Anal polyp
0.005 0.995 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.996 0.004
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.996 0.004
I01.8 Other acute rheumatic heart disease
0.000 0.996 0.004
I01.2 Acute rheumatic myocarditis
0.000 0.996 0.004
I01.1 Acute rheumatic endocarditis
0.000 0.996 0.004
I01.0 Acute rheumatic pericarditis
0.000 0.996 0.004
I02.9 Rheumatic chorea without heart involvement
0.000 0.996 0.004
I02.0 Rheumatic chorea with heart involvement
0.000 0.996 0.004
E83.5 Disorders of calcium metabolism
0.000 0.996 0.004
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.004 0.996 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.996 0.004
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.996 0.004
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.003 0.996 0.001
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.996 0.004
W19.4 Street and highway
0.004 0.996 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.996 0.004
I97.0 Postcardiotomy syndrome
0.000 0.996 0.004
I28 Other diseases of pulmonary vessels
0.001 0.996 0.003
I05-I09 Chronic rheumatic heart diseases
0.000 0.996 0.004
K08.3 Retained dental root
0.000 0.996 0.004
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.996 0.004
I73.8 Other specified peripheral vascular diseases
0.000 0.996 0.004
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.996 0.004
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.003 0.996 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.003 0.997 0.000
M20 Acquired deformities of fingers and toes
0.000 0.997 0.003
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.997 0.003
A41.8 Other specified septicaemia
0.003 0.997 0.000
I99 Other and unspecified disorders of circulatory system
0.000 0.997 0.003
H04.2 Epiphora
0.000 0.997 0.003
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.997 0.003
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.997 0.003
E28.3 Primary ovarian failure
0.003 0.997 0.000
S82.10 Fracture of upper end of tibia (closed)
0.003 0.997 0.000
N36.2 Urethral caruncle
0.003 0.997 0.000
E28 Ovarian dysfunction
0.003 0.997 0.000
E28.2 Polycystic ovarian syndrome
0.003 0.997 0.000
E61.1 Iron deficiency
0.000 0.997 0.003
E87.5 Hyperkalaemia
0.000 0.997 0.003
R09.1 Pleurisy
0.003 0.997 0.000
W19.1 Residential institution
0.003 0.997 0.000
O14.9 Preeclampsia, unspecified
0.003 0.997 0.000
H04 Disorders of lachrymal system
0.000 0.997 0.003
S20.8 Superficial injuries of other and unspecified parts of thorax
0.003 0.997 0.000
W19 Unspecified fall
0.003 0.997 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.997 0.002
I28.1 Aneurysm of pulmonary artery
0.001 0.997 0.002
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.997 0.002
I06 Rheumatic aortic valve diseases
0.000 0.997 0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
E87.4 Mixed disorder of acid-base balance
0.000 0.997 0.003
R16.0 Hepatomegaly, not elsewhere classified
0.003 0.997 0.000
C15.5 Lower third of oesophagus
0.000 0.997 0.003
A41 Other septicaemia
0.003 0.997 0.000
I28.8 Other specified diseases of pulmonary vessels
0.001 0.997 0.002
D73.0 Hyposplenism
0.003 0.997 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.997 0.003
E87.3 Alkalosis
0.000 0.997 0.003
L30.9 Dermatitis, unspecified
0.003 0.997 0.000
I09 Other rheumatic heart diseases
0.000 0.997 0.003
N36.8 Other specified disorders of urethra
0.003 0.997 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.997 0.003
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
I98.0 Cardiovascular syphilis
0.000 0.997 0.003
W19.9 Unspecified place
0.003 0.997 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.997 0.003
I51.6 Cardiovascular disease, unspecified
0.000 0.997 0.003
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.997 0.003
I51 Complications and ill-defined descriptions of heart disease
0.000 0.997 0.003
M20.3 Other deformity of hallux (acquired)
0.000 0.997 0.003
H04.8 Other disorders of lachrymal system
0.000 0.997 0.003
A41.0 Septicaemia due to Staphylococcus aureus
0.003 0.997 0.000
W19.6 Industrial and construction area
0.003 0.997 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.003 0.997 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
E28.9 Ovarian dysfunction, unspecified
0.002 0.997 0.000
E28.8 Other ovarian dysfunction
0.002 0.997 0.000
E28.1 Androgen excess
0.002 0.997 0.000
E28.0 Oestrogen excess
0.002 0.997 0.000
E23.7 Disorder of pituitary gland, unspecified
0.002 0.997 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.997 0.002
E34 Other endocrine disorders
0.002 0.997 0.000
I27 Other pulmonary heart diseases
0.000 0.997 0.002
A41.5 Septicaemia due to other Gram-negative organisms
0.003 0.997 0.000
H04.9 Disorder of lachrymal system, unspecified
0.000 0.997 0.002
E20-E35 Disorders of other endocrine glands
0.002 0.997 0.000
E34.0 Carcinoid syndrome
0.002 0.997 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.000 0.997 0.003
E23 Hypofunction and other disorders of pituitary gland
0.002 0.997 0.000
K91.3 Postoperative intestinal obstruction
0.000 0.998 0.002
H04.6 Other changes in lachrymal passages
0.000 0.998 0.002
H04.0 Dacryoadenitis
0.000 0.998 0.002
K08 Other disorders of teeth and supporting structures
0.000 0.998 0.002
E87.7 Fluid overload
0.000 0.998 0.002
W19.8 Other specified place
0.002 0.998 0.000
W19.5 Trade and service area
0.002 0.998 0.000
W19.0 Home
0.002 0.998 0.000
W19.7 Farm
0.002 0.998 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.998 0.002
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.000 0.998 0.002
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.998 0.002
I06.8 Other rheumatic aortic valve diseases
0.000 0.998 0.002
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.998 0.002
I06.1 Rheumatic aortic insufficiency
0.000 0.998 0.002
I06.0 Rheumatic aortic stenosis
0.000 0.998 0.002
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.998 0.002
K91.5 Postcholecystectomy syndrome
0.000 0.998 0.002
M20.0 Deformity of finger(s)
0.000 0.998 0.002
I51.7 Cardiomegaly
0.000 0.998 0.002
E23.2 Diabetes insipidus
0.002 0.998 0.000
A41.4 Septicaemia due to anaerobes
0.002 0.998 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.002 0.998 0.000
E61 Deficiency of other nutrient elements
0.000 0.998 0.002
I07 Rheumatic tricuspid valve diseases
0.000 0.998 0.002
I09.8 Other specified rheumatic heart diseases
0.000 0.998 0.002
I09.2 Chronic rheumatic pericarditis
0.000 0.998 0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.998 0.002
I09.0 Rheumatic myocarditis
0.000 0.998 0.002
N36 Other disorders of urethra
0.002 0.998 0.000
I08.8 Other multiple valve diseases
0.000 0.998 0.002
M20.2 Hallux rigidus
0.000 0.998 0.002
E29 Testicular dysfunction
0.002 0.998 0.000
S20 Superficial injury of thorax
0.002 0.998 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.998 0.002
I08 Multiple valve diseases
0.000 0.998 0.002
E34.9 Endocrine disorder, unspecified
0.002 0.998 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.998 0.002
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.998 0.002
E27.8 Other specified disorders of adrenal gland
0.002 0.998 0.000
I51.5 Myocardial degeneration
0.000 0.998 0.002
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.998 0.002
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.998 0.002
I10-I15 Hypertensive diseases
0.000 0.998 0.002
H04.4 Chronic inflammation of lachrymal passages
0.000 0.998 0.002
I09.9 Rheumatic heart disease, unspecified
0.000 0.998 0.002
E27 Other disorders of adrenal gland
0.002 0.998 0.000
E29.1 Testicular hypofunction
0.002 0.998 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.998 0.002
A04.8 Other specified bacterial intestinal infections
0.000 0.998 0.002
D73.3 Abscess of spleen
0.002 0.998 0.000
S20.2 Contusion of thorax
0.002 0.998 0.000
F06.7 Mild cognitive disorder
0.002 0.998 0.000
H52.1 Myopia
0.002 0.998 0.000
I51.4 Myocarditis, unspecified
0.000 0.998 0.002
W13.9 Unspecified place
0.000 0.998 0.002
D73 Diseases of spleen
0.002 0.998 0.000
I05 Rheumatic mitral valve diseases
0.000 0.998 0.002
E34.5 Androgen resistance syndrome
0.002 0.998 0.000
E34.4 Constitutional tall stature
0.002 0.998 0.000
E34.3 Short stature, not elsewhere classified
0.002 0.998 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.002 0.998 0.000
E34.1 Other hypersecretion of intestinal hormones
0.002 0.998 0.000
H83.0 Labyrinthitis
0.000 0.998 0.002
I27.1 Kyphoscoliotic heart disease
0.000 0.998 0.002
W19.3 Sports and athletics area
0.002 0.998 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.002 0.998 0.000
E32 Diseases of thymus
0.002 0.998 0.000
E31 Polyglandular dysfunction
0.002 0.998 0.000
E30 Disorders of puberty, not elsewhere classified
0.002 0.998 0.000
E25 Adrenogenital disorders
0.002 0.998 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.998 0.002
K08.2 Atrophy of edentulous alveolar ridge
0.000 0.998 0.002
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.000 0.998 0.002
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.002 0.998 0.000
E23.6 Other disorders of pituitary gland
0.002 0.998 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.002 0.998 0.000
E23.1 Drug-induced hypopituitarism
0.002 0.998 0.000
E34.8 Other specified endocrine disorders
0.002 0.998 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.998 0.002
K08.0 Exfoliation of teeth due to systemic causes
0.000 0.998 0.002
W19.09 Unspecified fall; Home; During unspecified activity
0.002 0.998 0.000
W19.08 Unspecified fall; Home; While engaged in other specified activities
0.002 0.998 0.000
W19.59 Unspecified fall; Trade and service area; During unspecified activity
0.002 0.998 0.000
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity
0.002 0.998 0.000
E20 Hypoparathyroidism
0.002 0.998 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.998 0.002
S51.0 Open wound of elbow
0.002 0.998 0.000
E26 Hyperaldosteronism
0.002 0.998 0.000
E24 Cushing's syndrome
0.002 0.998 0.000
G20 Parkinson's disease
0.000 0.998 0.002
S20.3 Other superficial injuries of front wall of thorax
0.002 0.998 0.000
D73.5 Infarction of spleen
0.002 0.998 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.998 0.002
E61.8 Deficiency of other specified nutrient elements
0.000 0.998 0.002
E61.7 Deficiency of multiple nutrient elements
0.000 0.998 0.002
E61.6 Vanadium deficiency
0.000 0.998 0.002
E61.5 Molybdenum deficiency
0.000 0.998 0.002
E61.4 Chromium deficiency
0.000 0.998 0.002
E61.3 Manganese deficiency
0.000 0.998 0.002
E61.2 Magnesium deficiency
0.000 0.998 0.002
E61.0 Copper deficiency
0.000 0.998 0.002
I07.9 Tricuspid valve disease, unspecified
0.000 0.998 0.002
I07.8 Other tricuspid valve diseases
0.000 0.998 0.002
I07.2 Tricuspid stenosis with insufficiency
0.000 0.998 0.002
I07.0 Tricuspid stenosis
0.000 0.998 0.002
K91.1 Postgastric surgery syndromes
0.000 0.998 0.002
N05.9 Unspecified
0.002 0.998 0.000
N36.9 Urethral disorder, unspecified
0.002 0.998 0.000
N36.1 Urethral diverticulum
0.002 0.998 0.000
N36.0 Urethral fistula
0.002 0.998 0.000
E22 Hyperfunction of pituitary gland
0.002 0.998 0.000
E27.1 Primary adrenocortical insufficiency
0.002 0.998 0.000
E29.9 Testicular dysfunction, unspecified
0.002 0.998 0.000
E29.8 Other testicular dysfunction
0.002 0.998 0.000
E29.0 Testicular hyperfunction
0.002 0.998 0.000
S20.7 Multiple superficial injuries of thorax
0.002 0.998 0.000
S20.4 Other superficial injuries of back wall of thorax
0.002 0.998 0.000
S20.1 Other and unspecified superficial injuries of breast
0.002 0.998 0.000
S20.0 Contusion of breast
0.002 0.998 0.000
S51.8 Open wound of other parts of forearm
0.002 0.998 0.000
W19.2 School, other institution and public administrative area
0.002 0.998 0.000
E27.9 Disorder of adrenal gland, unspecified
0.002 0.998 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.998 0.002
K08.9 Disorder of teeth and supporting structures, unspecified
0.000 0.998 0.002
N05.1 Focal and segmental glomerular lesions
0.002 0.998 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.998 0.002
I13 Hypertensive heart and renal disease
0.000 0.998 0.002
S29.9 Unspecified injury of thorax
0.002 0.998 0.000
E27.5 Adrenomedullary hyperfunction
0.002 0.998 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.002 0.998 0.000
E27.0 Other adrenocortical overactivity
0.002 0.998 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.998 0.002
L05.0 Pilonidal cyst with abscess
0.000 0.998 0.002
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.002 0.998 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.998 0.000
G70.0 Myasthenia gravis
0.002 0.998 0.000
R09.3 Abnormal sputum
0.002 0.998 0.000
I11 Hypertensive heart disease
0.000 0.998 0.002
C15.9 Oesophagus, unspecified
0.000 0.998 0.002
D21.2 Connective and other soft tissue of lower limb, including hip
0.002 0.998 0.000
I27.9 Pulmonary heart disease, unspecified
0.001 0.998 0.001
D73.9 Disease of spleen, unspecified
0.002 0.998 0.000
D73.4 Cyst of spleen
0.002 0.998 0.000
D73.2 Chronic congestive splenomegaly
0.002 0.998 0.000
D73.1 Hypersplenism
0.002 0.998 0.000
I05.8 Other mitral valve diseases
0.000 0.998 0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.002 0.998 0.000
L30 Other dermatitis
0.002 0.998 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.998 0.002
E25.9 Adrenogenital disorder, unspecified
0.002 0.998 0.000
E25.8 Other adrenogenital disorders
0.002 0.998 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.002 0.998 0.000
E30.9 Disorder of puberty, unspecified
0.002 0.998 0.000
E30.8 Other disorders of puberty
0.002 0.998 0.000
E30.1 Precocious puberty
0.002 0.998 0.000
E30.0 Delayed puberty
0.002 0.998 0.000
E31.9 Polyglandular dysfunction, unspecified
0.002 0.998 0.000
E31.8 Other polyglandular dysfunction
0.002 0.998 0.000
E31.1 Polyglandular hyperfunction
0.002 0.998 0.000
E31.0 Autoimmune polyglandular failure
0.002 0.998 0.000
E32.9 Disease of thymus, unspecified
0.002 0.998 0.000
E32.8 Other diseases of thymus
0.002 0.998 0.000
E32.1 Abscess of thymus
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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