TreeWAS – Variant ID: rs4841452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.946	0.054	0.000
J44 Other chronic obstructive pulmonary disease	0.514	0.486	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.398	0.602	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.362	0.638	0.000
I10-I15 Hypertensive diseases	0.347	0.653	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.337	0.663	0.000
I12 Hypertensive renal disease	0.287	0.713	0.000
I12.9 Hypertensive renal disease without renal failure	0.271	0.729	0.000
I13 Hypertensive heart and renal disease	0.249	0.751	0.000
J40-J47 Chronic lower respiratory diseases	0.209	0.791	0.000
I15 Secondary hypertension	0.204	0.796	0.000
J46 Status asthmaticus	0.200	0.800	0.000
I11 Hypertensive heart disease	0.197	0.803	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.179	0.821	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.179	0.821	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.179	0.821	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.179	0.821	0.000
J45 Asthma	0.166	0.834	0.000
I15.2 Hypertension secondary to endocrine disorders	0.154	0.845	0.000
J42 Unspecified chronic bronchitis	0.152	0.848	0.000
I15.8 Other secondary hypertension	0.146	0.854	0.000
J41 Simple and mucopurulent chronic bronchitis	0.146	0.854	0.000
I15.0 Renovascular hypertension	0.144	0.856	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.142	0.858	0.000
N10 Acute tubulo-interstitial nephritis	0.139	0.861	0.000
N13 Obstructive and reflux uropathy	0.139	0.861	0.000
N10-N16 Renal tubulo-interstitial diseases	0.138	0.862	0.000
J45.0 Predominantly allergic asthma	0.136	0.864	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.133	0.867	0.000
I15.9 Seconday hypertension, unspecified	0.131	0.869	0.000
J45.1 Nonallergic asthma	0.130	0.870	0.000
N13.4 Hydroureter	0.127	0.873	0.000
J47 Bronchiectasis	0.123	0.877	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.121	0.879	0.000
J45.8 Mixed asthma	0.120	0.880	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.119	0.881	0.000
I15.1 Hypertension secondary to other renal disorders	0.112	0.887	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.107	0.893	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.107	0.893	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.107	0.893	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.105	0.895	0.000
J41.1 Mucopurulent chronic bronchitis	0.105	0.895	0.000
N15 Other renal tubulo-interstitial diseases	0.103	0.897	0.000
J41.0 Simple chronic bronchitis	0.101	0.899	0.000
J45.9 Asthma, unspecified	0.100	0.900	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.099	0.901	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.091	0.909	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.090	0.910	0.000
N13.8 Other obstructive and reflux uropathy	0.087	0.913	0.000
N13.3 Other and unspecified hydronephrosis	0.086	0.914	0.000
J43 Emphysema	0.082	0.918	0.000
N15.1 Renal and perinephric abscess	0.081	0.919	0.000
K22.7 Barrett's oesophagus	0.080	0.920	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.079	0.921	0.000
I12.0 Hypertensive renal disease with renal failure	0.074	0.926	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.074	0.926	0.000
N15.0 Balkan nephropathy	0.074	0.926	0.000
N13.6 Pyonephrosis	0.072	0.928	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.071	0.929	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.071	0.929	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.071	0.929	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.071	0.929	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.071	0.929	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.071	0.929	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.071	0.929	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.070	0.930	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.065	0.934	0.000
N14.3 Nephropathy induced by heavy metals	0.065	0.934	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.065	0.934	0.000
N14.0 Analgesic nephropathy	0.065	0.934	0.000
N11 Chronic tubulo-interstitial nephritis	0.063	0.937	0.000
J43.8 Other emphysema	0.061	0.938	0.000
J43.1 Panlobular emphysema	0.059	0.941	0.000
J43.0 MacLeod's syndrome	0.059	0.941	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.057	0.943	0.000
J40 Bronchitis, not specified as acute or chronic	0.046	0.954	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.045	0.955	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.043	0.956	0.000
J43.2 Centrilobular emphysema	0.041	0.959	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.041	0.959	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.034	0.966	0.000
E87.7 Fluid overload	0.033	0.967	0.000
N11.1 Chronic obstructive pyelonephritis	0.032	0.967	0.001
E87.6 Hypokalaemia	0.032	0.968	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.029	0.971	0.000
E87.3 Alkalosis	0.025	0.975	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.025	0.975	0.000
K44 Diaphragmatic hernia	0.025	0.975	0.000
F17.1 Harmful use	0.024	0.976	0.000
E66.8 Other obesity	0.024	0.976	0.000
E66.9 Obesity, unspecified	0.023	0.977	0.000
J43.9 Emphysema, unspecified	0.023	0.977	0.000
E87.0 Hyperosmolality and hypernatraemia	0.022	0.978	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.021	0.979	0.000
E66 Obesity	0.021	0.979	0.000
K44.1 Diaphragmatic hernia with gangrene	0.021	0.979	0.000
E87.4 Mixed disorder of acid-base balance	0.021	0.979	0.000
I35.1 Aortic (valve) insufficiency	0.019	0.981	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.019	0.981	0.000
I35 Nonrheumatic aortic valve disorders	0.017	0.983	0.000
O62.2 Other uterine inertia	0.000	0.984	0.016
I74 Arterial embolism and thrombosis	0.016	0.984	0.000
E66.1 Drug-induced obesity	0.015	0.985	0.000
I74.8 Embolism and thrombosis of other arteries	0.015	0.985	0.000
E89.0 Postprocedural hypothyroidism	0.015	0.985	0.000
I35.8 Other aortic valve disorders	0.015	0.985	0.000
I35.0 Aortic (valve) stenosis	0.014	0.986	0.000
E87.2 Acidosis	0.014	0.986	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.014	0.986	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.013	0.986	0.000
I35.9 Aortic valve disorder, unspecified	0.013	0.986	0.000
R40.0 Somnolence	0.013	0.987	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.013	0.987	0.000
E70-E90 Metabolic disorders	0.013	0.987	0.000
E66.0 Obesity due to excess calories	0.012	0.987	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.012	0.988	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.012	0.988	0.000
E73 Lactose intolerance	0.012	0.988	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.012	0.988	0.000
O62 Abnormalities of forces of labour	0.000	0.988	0.012
E80 Disorders of porphyrin and bilirubin metabolism	0.012	0.988	0.000
E73.9 Lactose intolerance, unspecified	0.012	0.988	0.000
E89.1 Postprocedural hypoinsulinaemia	0.011	0.989	0.000
E87.5 Hyperkalaemia	0.011	0.989	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.989	0.011
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.011	0.989	0.000
E89.4 Postprocedural ovarian failure	0.011	0.989	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.010	0.989	0.000
E89.2 Postprocedural hypoparathyroidism	0.011	0.989	0.000
E80.6 Other disorders of bilirubin metabolism	0.010	0.990	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.990	0.010
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.010	0.990	0.000
E89.5 Postprocedural testicular hypofunction	0.010	0.990	0.000
E84 Cystic fibrosis	0.010	0.990	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.010	0.990	0.000
E79 Disorders of purine and pyrimidine metabolism	0.010	0.990	0.000
O62.1 Secondary uterine inertia	0.000	0.990	0.010
E74 Other disorders of carbohydrate metabolism	0.009	0.990	0.000
E72 Other disorders of amino-acid metabolism	0.009	0.991	0.000
E80.1 Porphyria cutanea tarda	0.009	0.991	0.000
E65-E68 Obesity and other hyperalimentation	0.009	0.991	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.009	0.991	0.000
E80.4 Gilbert's syndrome	0.009	0.991	0.000
O62.0 Primary inadequate contractions	0.000	0.991	0.009
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.009	0.991	0.000
E77 Disorders of glycoprotein metabolism	0.009	0.991	0.000
E76 Disorders of glycosaminoglycan metabolism	0.009	0.991	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.009	0.991	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.009	0.991	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
E73.8 Other lactose intolerance	0.009	0.991	0.000
E73.1 Secondary lactase deficiency	0.009	0.991	0.000
E73.0 Congenital lactase deficiency	0.009	0.991	0.000
E70 Disorders of aromatic amino-acid metabolism	0.009	0.991	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.991	0.009
I74.5 Embolism and thrombosis of iliac artery	0.009	0.991	0.000
O62.8 Other abnormalities of forces of labour	0.000	0.991	0.009
E80.7 Disorder of bilirubin metabolism, unspecified	0.008	0.991	0.000
E80.5 Crigler-Najjar syndrome	0.008	0.991	0.000
E80.3 Defects of catalase and peroxydase	0.008	0.991	0.000
E80.0 Hereditary erythropoietic porphyria	0.008	0.991	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.008	0.991	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.008	0.991	0.000
E85 Amyloidosis	0.008	0.992	0.000
E80.2 Other porphyria	0.008	0.992	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.008	0.992	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.008	0.992	0.000
Z41 Procedures for purposes other than remedying health state	0.008	0.992	0.000
I95.1 Orthostatic hypotension	0.008	0.992	0.000
E84.9 Cystic fibrosis, unspecified	0.007	0.992	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.007	0.992	0.000
E89.3 Postprocedural hypopituitarism	0.007	0.993	0.000
E84.8 Cystic fibrosis with other manifestations	0.007	0.993	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.007	0.993	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.007	0.993	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.007	0.993	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.007	0.993	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.007	0.993	0.000
E79.1 Lesch-Nyhan syndrome	0.007	0.993	0.000
E72.0 Disorders of amino-acid transport	0.007	0.993	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.007	0.993	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.007	0.993	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.007	0.993	0.000
E74.2 Disorders of galactose metabolism	0.007	0.993	0.000
E74.1 Disorders of fructose metabolism	0.007	0.993	0.000
E74.0 Glycogen storage disease	0.007	0.993	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.007	0.993	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.007	0.993	0.000
E72.5 Disorders of glycine metabolism	0.007	0.993	0.000
E72.4 Disorders of ornithine metabolism	0.007	0.993	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.007	0.993	0.000
E72.2 Disorders of urea cycle metabolism	0.007	0.993	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.007	0.993	0.000
E67 Other hyperalimentation	0.007	0.993	0.000
E68 Sequelae of hyperalimentation	0.007	0.993	0.000
E71.3 Disorders of fatty-acid metabolism	0.007	0.993	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.007	0.993	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.007	0.993	0.000
E71.0 Maple-syrup-urine disease	0.007	0.993	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.007	0.993	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.007	0.993	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.007	0.993	0.000
E76.2 Other mucopolysaccharidoses	0.007	0.993	0.000
E76.1 Mucopolysaccharidosis, type II	0.007	0.993	0.000
E76.0 Mucopolysaccharidosis, type I	0.007	0.993	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.007	0.993	0.000
E77.8 Other disorders of glycoprotein metabolism	0.007	0.993	0.000
E77.1 Defects in glycoprotein degradation	0.007	0.993	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.007	0.993	0.000
R40 Somnolence, stupor and coma	0.007	0.993	0.000
O62.3 Precipitate labour	0.000	0.993	0.007
E85.3 Secondary systemic amyloidosis	0.007	0.993	0.000
N76.2 Acute vulvitis	0.007	0.993	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.006	0.993	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.006	0.993	0.000
E70.2 Disorders of tyrosine metabolism	0.006	0.993	0.000
E70.1 Other hyperphenylalaninaemias	0.006	0.993	0.000
E70.0 Classical phenylketonuria	0.006	0.993	0.000
E75.6 Lipid storage disorder, unspecified	0.006	0.994	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.006	0.994	0.000
E75.3 Sphingolipidosis, unspecified	0.006	0.994	0.000
E75.1 Other gangliosidosis	0.006	0.994	0.000
E75.0 GM2 gangliosidosis	0.006	0.994	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.006	0.994	0.000
E85.8 Other amyloidosis	0.006	0.994	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.006	0.994	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.006	0.994	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.006	0.994	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.994	0.006
E07.9 Disorder of thyroid, unspecified	0.000	0.994	0.006
E70.3 Albinism	0.006	0.994	0.000
E75.2 Other sphingolipidosis	0.006	0.994	0.000
N30.2 Other chronic cystitis	0.000	0.994	0.006
E75.5 Other lipid storage disorders	0.006	0.994	0.000
I95.0 Idiopathic hypotension	0.006	0.994	0.000
I95 Hypotension	0.006	0.994	0.000
Z41.3 Ear piercing	0.006	0.994	0.000
Z41.0 Hair transplant	0.006	0.994	0.000
Z41.2 Routine and ritual circumcision	0.006	0.994	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
E04.0 Non-toxic diffuse goitre	0.006	0.994	0.000
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.006	0.994	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.006	0.994	0.000
I95.8 Other hypotension	0.005	0.995	0.000
R40.2 Coma, unspecified	0.005	0.995	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.005	0.995	0.000
E85.9 Amyloidosis, unspecified	0.005	0.995	0.000
E67.8 Other specified hyperalimentation	0.005	0.995	0.000
E67.3 Hypervitaminosis D	0.005	0.995	0.000
E67.2 Megavitamin-B6 syndrome	0.005	0.995	0.000
E67.1 Hypercarotenaemia	0.005	0.995	0.000
E67.0 Hypervitaminosis A	0.005	0.995	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.005	0.995	0.000
S02.2 Fracture of nasal bones	0.001	0.995	0.004
E85.4 Organ-limited amyloidosis	0.005	0.995	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.005	0.995	0.000
R40.1 Stupor	0.005	0.995	0.000
S05.8 Other injuries of eye and orbit	0.005	0.995	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.995	0.005
K43.0 Ventral hernia with obstruction, without gangrene	0.005	0.995	0.000
R44.1 Visual hallucinations	0.005	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.005	0.995	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.995	0.005
S02.50 Fracture of tooth (closed)	0.005	0.995	0.000
E04.2 Non-toxic multinodular goitre	0.005	0.995	0.000
E04 Other non-toxic goitre	0.005	0.995	0.000
E65 Localised adiposity	0.005	0.995	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.005	0.995	0.000
E88 Other metabolic disorders	0.005	0.995	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.005	0.995	0.000
E04.9 Non-toxic goitre, unspecified	0.004	0.996	0.000
M54.5 Low back pain	0.004	0.996	0.000
R44.0 Auditory hallucinations	0.004	0.996	0.000
I45.9 Conduction disorder, unspecified	0.004	0.996	0.000
U80.1 Methicillin resistant agent	0.004	0.996	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
I00-I02 Acute rheumatic fever	0.004	0.996	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.004	0.996	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.004
S05 Injury of eye and orbit	0.004	0.996	0.000
K56.4 Other impaction of intestine	0.000	0.996	0.004
E88.2 Lipomatosis, not elsewhere classified	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
I70 Atherosclerosis	0.004	0.996	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
S02.5 Fracture of tooth	0.003	0.996	0.000
I24 Other acute ischaemic heart diseases	0.004	0.996	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.996	0.004
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
M54.55 Low back pain (Thoracolumbar region)	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
I99 Other and unspecified disorders of circulatory system	0.004	0.996	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.004	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.004	0.996	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.004	0.996	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
E00-E07 Disorders of thyroid gland	0.004	0.996	0.000
E07 Other disorders of thyroid	0.001	0.996	0.002
E04.8 Other specified non-toxic goitre	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
S05.9 Injury of eye and orbit, part unspecified	0.004	0.996	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
I24.1 Dressler's syndrome	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.001	0.996	0.002
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.996	0.000
F17.3 Withdrawal state	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.003	0.996	0.000
M54.52 Low back pain-Cervical	0.004	0.996	0.000
B00.9 Herpesviral infection, unspecified	0.000	0.996	0.004
I97.9 Postprocedural disorder of circulatory system, unspecified	0.003	0.996	0.000
F17.8 Other mental and behavioural disorders	0.003	0.996	0.000
F17.7 Residual and late-onset psychotic disorder	0.003	0.996	0.000
F17.6 Amnesic syndrome	0.003	0.996	0.000
F17.5 Psychotic disorder	0.003	0.996	0.000
F17.4 Withdrawal state with delirium	0.003	0.996	0.000
F17.0 Acute intoxication	0.003	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.996	0.000
S00.8 Superficial injury of other parts of head	0.004	0.996	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.996	0.000
M54.56 Low back pain (Lumbar region)	0.004	0.996	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.004	0.996	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.003	0.996	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.996	0.000
M54.57 Low back pain (Lumbosacral region)	0.003	0.997	0.000
M54.53 Low back pain-Cervicothoracic	0.003	0.997	0.000
M54.51 Low back pain-Occipit-atl-axl	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
E88.9 Metabolic disorder, unspecified	0.003	0.997	0.000
E88.8 Other specified metabolic disorders	0.003	0.997	0.000
M13.9 Arthritis, unspecified	0.003	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000
I97.0 Postcardiotomy syndrome	0.003	0.997	0.000
S03.2 Dislocation of tooth	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
S06 Intracranial injury	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
I34.1 Mitral (valve) prolapse	0.000	0.997	0.003
I70.0 Atherosclerosis of aorta	0.003	0.997	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.003	0.997	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
M54.54 Low back pain-Thoracic	0.003	0.997	0.000
F17.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
I02 Rheumatic chorea	0.003	0.997	0.000
I01 Rheumatic fever with heart involvement	0.003	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.003	0.997	0.000
S00-S09 Injuries to the head	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.003	0.997	0.000
S00.4 Superficial injury of ear	0.003	0.997	0.000
S06.3 Focal brain injury	0.003	0.997	0.000
M94.2 Chondromalacia	0.000	0.997	0.003
R44.2 Other hallucinations	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.003	0.997	0.000
S05.7 Avulsion of eye	0.003	0.997	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
M54.59 Low back pain (Site unspecified)	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.997	0.003
K22.1 Ulcer of oesophagus	0.003	0.997	0.000
S00 Superficial injury of head	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.003	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
E88.3 Tumour lysis syndrome	0.003	0.997	0.000
E83 Disorders of mineral metabolism	0.003	0.997	0.000
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
M13.0 Polyarthritis, unspecified	0.003	0.997	0.000
S03.1 Dislocation of septal cartilage of nose	0.003	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.003	0.997	0.000
S03.0 Dislocation of jaw	0.003	0.997	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.001	0.997	0.002
E07.0 Hypersecretion of calcitonin	0.001	0.997	0.002
I70.8 Atherosclerosis of other arteries	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
S00.0 Superficial injury of scalp	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I45.2 Bifascicular block	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M13.98 Arthritis, unspecified (Other)	0.003	0.997	0.000
I77.2 Rupture of artery	0.003	0.997	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.003	0.997	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.003	0.997	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.997	0.000
H26.8 Other specified cataract	0.003	0.997	0.000
S00.3 Superficial injury of nose	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.003	0.997	0.000
R41.2 Retrograde amnesia	0.003	0.997	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.003	0.997	0.000
S03.4 Sprain and strain of jaw	0.003	0.997	0.000
S03.3 Dislocation of other and unspecified parts of head	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
M13 Other arthritis	0.003	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.003	0.997	0.000
R52.0 Acute pain	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.997	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.003	0.997	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.003	0.997	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.003	0.997	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.003	0.997	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.003	0.997	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.003	0.997	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.003	0.997	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.003	0.997	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.003	0.997	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.003	0.997	0.000
C81.1 Nodular sclerosis	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.001	0.997	0.001
S09.8 Other specified injuries of head	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.001	0.997	0.002
J30.3 Other allergic rhinitis	0.000	0.997	0.003
N76.3 Subacute and chronic vulvitis	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.003	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.002	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.002	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.002	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.002	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.002	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.002	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.002	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
I40.0 Infective myocarditis	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.997	0.001
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.003	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
N76.0 Acute vaginitis	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.002	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.002	0.997	0.000
M94.29 Chondromalacia (Site unspecified)	0.000	0.997	0.002
M94.28 Chondromalacia (Other)	0.000	0.997	0.002
M94.27 Chondromalacia (Ankle and foot)	0.000	0.997	0.002
M94.25 Chondromalacia (Pelvic region and thigh)	0.000	0.997	0.002
M94.24 Chondromalacia (Hand)	0.000	0.997	0.002
M94.23 Chondromalacia (Forearm)	0.000	0.997	0.002
M94.22 Chondromalacia (Upper arm)	0.000	0.997	0.002
M94.21 Chondromalacia (Shoulder region)	0.000	0.997	0.002
M94.20 Chondromalacia (Multiple sites)	0.000	0.997	0.002
C43.9 Malignant melanoma of skin, unspecified	0.003	0.997	0.000
N76.6 Ulceration of vulva	0.003	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.003	0.997	0.000
I40 Acute myocarditis	0.003	0.997	0.000
M54.50 Low back pain (Multiple sites in spine)	0.002	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.997	0.000
M05.1 Rheumatoid lung disease	0.002	0.997	0.000
M05.0 Felty's syndrome	0.002	0.997	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.002	0.997	0.000
S09 Other and unspecified injuries of head	0.003	0.997	0.000
I30-I52 Other forms of heart disease	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations