TreeWAS – Variant ID: rs2575029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I51.7 Cardiomegaly	0.000	0.766	0.234
I51 Complications and ill-defined descriptions of heart disease	0.000	0.878	0.122
I51.8 Other ill-defined heart diseases	0.000	0.880	0.120
I51.6 Cardiovascular disease, unspecified	0.000	0.904	0.095
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.912	0.088
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.915	0.085
I51.0 Cardiac septal defect, acquired	0.000	0.916	0.084
I51.5 Myocardial degeneration	0.000	0.919	0.081
I51.4 Myocarditis, unspecified	0.000	0.934	0.066
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.940	0.059
I51.9 Heart disease, unspecified	0.000	0.946	0.054
S72.00 Fracture of neck of femur (closed)	0.054	0.946	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.953	0.047
S72.0 Fracture of neck of femur	0.036	0.964	0.000
I12 Hypertensive renal disease	0.000	0.971	0.029
S72.01 Fracture of neck of femur (open)	0.026	0.974	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.975	0.025
S72 Fracture of femur	0.023	0.977	0.000
S72.2 Subtrochanteric fracture	0.020	0.980	0.000
S72.4 Fracture of lower end of femur	0.019	0.981	0.000
S72.9 Fracture of femur, part unspecified	0.018	0.982	0.000
S72.20 Subtrochanteric fracture (closed)	0.018	0.982	0.000
S72.7 Multiple fractures of femur	0.017	0.983	0.000
S72.3 Fracture of shaft of femur	0.017	0.983	0.000
S72.8 Fractures of other parts of femur	0.015	0.985	0.000
S72.41 Fracture of lower end of femur (open)	0.015	0.985	0.000
S72.21 Subtrochanteric fracture (open)	0.014	0.985	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.014	0.985	0.000
S72.40 Fracture of lower end of femur (closed)	0.014	0.986	0.000
S22.30 Fracture of rib (closed)	0.014	0.986	0.000
S72.91 Fracture of femur, part unspecified (open)	0.013	0.987	0.000
S72.70 Multiple fractures of femur (closed)	0.013	0.987	0.000
S72.30 Fracture of shaft of femur (closed)	0.013	0.987	0.000
S72.1 Pertrochanteric fracture	0.013	0.987	0.000
S72.71 Multiple fractures of femur (open)	0.012	0.987	0.000
E10.3 With ophthalmic complications	0.000	0.987	0.013
S72.31 Fracture of shaft of femur (open)	0.012	0.988	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.988	0.012
S72.81 Fractures of other parts of femur (open)	0.011	0.989	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.989	0.011
E10 Insulin-dependent diabetes mellitus	0.000	0.989	0.011
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.990	0.010
E10.4 With neurological complications	0.000	0.990	0.010
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.990	0.010
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.991	0.009
S72.80 Fractures of other parts of femur (closed)	0.009	0.991	0.000
S72.11 Pertrochanteric fracture (open)	0.009	0.991	0.000
E10.2 With renal complications	0.000	0.991	0.009
E10.7 With multiple complications	0.000	0.991	0.009
E10.6 With other specified complications	0.000	0.991	0.009
E10.0 With coma	0.000	0.991	0.009
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.991	0.008
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.992	0.008
N85.4 Malposition of uterus	0.008	0.992	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.992	0.008
N85.8 Other specified noninflammatory disorders of uterus	0.008	0.992	0.000
S70-S79 Injuries to the hip and thigh	0.008	0.992	0.000
E10.5 With peripheral circulatory complications	0.000	0.992	0.008
M65.34 Trigger finger-Hand	0.000	0.992	0.008
N85 Other noninflammatory disorders of uterus, except cervix	0.008	0.992	0.000
E10.1 With ketoacidosis	0.000	0.992	0.008
E10.8 With unspecified complications	0.000	0.992	0.008
J02.9 Acute pharyngitis, unspecified	0.000	0.992	0.008
M65 Synovitis and tenosynovitis	0.000	0.992	0.008
N85.1 Endometrial adenomatous hyperplasia	0.008	0.992	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.007	0.992	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.993	0.007
M65.3 Trigger finger	0.000	0.993	0.007
E10.9 Without complications	0.000	0.993	0.007
I10-I15 Hypertensive diseases	0.000	0.993	0.007
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.993	0.007
S22.3 Fracture of rib	0.007	0.993	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.993	0.007
M65.1 Other infective (teno)synovitis	0.000	0.994	0.006
S78 Traumatic amputation of hip and thigh	0.006	0.994	0.000
S77 Crushing injury of hip and thigh	0.006	0.994	0.000
S70 Superficial injury of hip and thigh	0.006	0.994	0.000
N85.5 Inversion of uterus	0.006	0.994	0.000
L03.2 Cellulitis of face	0.000	0.994	0.006
I13 Hypertensive heart and renal disease	0.000	0.994	0.006
S79 Other and unspecified injuries of hip and thigh	0.006	0.994	0.000
S74 Injury of nerves at hip and thigh level	0.006	0.994	0.000
S71 Open wound of hip and thigh	0.006	0.994	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.994	0.006
N85.3 Subinvolution of uterus	0.006	0.994	0.000
M65.0 Abscess of tendon sheath	0.000	0.994	0.006
S76 Injury of muscle and tendon at hip and thigh level	0.006	0.994	0.000
S75 Injury of blood vessels at hip and thigh level	0.006	0.994	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.006	0.994	0.000
N85.7 Haematometra	0.006	0.994	0.000
N85.2 Hypertrophy of uterus	0.006	0.994	0.000
M65.38 Trigger finger-Other	0.000	0.994	0.005
M65.37 Trigger finger-Ankle/foot	0.000	0.994	0.005
M65.36 Trigger finger-Lower leg	0.000	0.994	0.005
M65.35 Trigger finger-Pelvic/thigh	0.000	0.994	0.005
M65.33 Trigger finger-Forearm	0.000	0.994	0.005
M65.32 Trigger finger-Upper arm	0.000	0.994	0.005
M65.31 Trigger finger-Shldr region	0.000	0.994	0.005
M65.30 Trigger finger-Mult sites	0.000	0.994	0.005
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.994	0.005
I15 Secondary hypertension	0.000	0.994	0.005
M65.2 Calcific tendinitis	0.000	0.994	0.005
N85.6 Intra-uterine synechiae	0.005	0.995	0.000
S22.31 Fracture of rib (open)	0.005	0.995	0.000
S72.10 Pertrochanteric fracture (closed)	0.005	0.995	0.000
C81 Hodgkin's disease	0.000	0.995	0.005
S70.1 Contusion of thigh	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.995	0.005
I08 Multiple valve diseases	0.000	0.995	0.005
S70.8 Other superficial injuries of hip and thigh	0.005	0.995	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.995	0.005
I11 Hypertensive heart disease	0.000	0.995	0.005
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.995	0.005
C81.1 Nodular sclerosis	0.000	0.995	0.005
I07.1 Tricuspid insufficiency	0.000	0.995	0.005
M65.39 Trigger finger-Site unspec	0.000	0.995	0.005
M65.8 Other synovitis and tenosynovitis	0.000	0.995	0.005
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.995	0.005
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.995	0.005
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.995	0.005
S71.0 Open wound of hip	0.005	0.995	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.000	0.995	0.004
M65.18 Other infective (teno)synovitis (Other)	0.000	0.995	0.004
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.000	0.995	0.004
M65.16 Other infective (teno)synovitis (Lower leg)	0.000	0.995	0.004
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.000	0.995	0.004
M65.13 Other infective (teno)synovitis (Forearm)	0.000	0.995	0.004
M65.12 Other infective (teno)synovitis (Upper arm)	0.000	0.995	0.004
M65.11 Other infective (teno)synovitis (Shoulder region)	0.000	0.995	0.004
M65.10 Other infective (teno)synovitis (Multiple sites)	0.000	0.995	0.004
S77.2 Crushing injury of hip with thigh	0.004	0.995	0.000
S77.1 Crushing injury of thigh	0.004	0.995	0.000
S77.0 Crushing injury of hip	0.004	0.995	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.004	0.995	0.000
S78.1 Traumatic amputation at level between hip and knee	0.004	0.995	0.000
S78.0 Traumatic amputation at hip joint	0.004	0.995	0.000
S71.7 Multiple open wounds of of hip and thigh	0.004	0.995	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.004	0.995	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.995	0.004
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.004	0.995	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.004	0.995	0.000
S74.8 Injury of other nerves at hip and thigh level	0.004	0.995	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.004	0.995	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.004	0.995	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.004	0.995	0.000
S79.7 Multiple injuries of hip and thigh	0.004	0.995	0.000
C81.0 Lymphocytic predominance	0.000	0.995	0.004
I15.0 Renovascular hypertension	0.000	0.995	0.004
S70.7 Multiple superficial injuries of hip and thigh	0.004	0.995	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.004	0.995	0.000
S79.9 Unspecified injury of hip and thigh	0.004	0.995	0.000
S79.8 Other specified injuries of hip and thigh	0.004	0.995	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.995	0.004
S73.1 Sprain and strain of hip	0.004	0.996	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.996	0.004
M65.04 Abscess of tendon sheath (Hand)	0.000	0.996	0.004
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
S76.0 Injury of muscle and tendon of hip	0.004	0.996	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.000	0.996	0.004
M65.08 Abscess of tendon sheath (Other)	0.000	0.996	0.004
M65.07 Abscess of tendon sheath (Ankle and foot)	0.000	0.996	0.004
M65.06 Abscess of tendon sheath (Lower leg)	0.000	0.996	0.004
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.000	0.996	0.004
M65.03 Abscess of tendon sheath (Forearm)	0.000	0.996	0.004
M65.02 Abscess of tendon sheath (Upper arm)	0.000	0.996	0.004
M65.01 Abscess of tendon sheath (Shoulder region)	0.000	0.996	0.004
M65.00 Abscess of tendon sheath (Multiple sites)	0.000	0.996	0.004
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.004	0.996	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.004	0.996	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.004	0.996	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.004	0.996	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.004	0.996	0.000
S76.1 Injury of quadriceps muscle and tendon	0.004	0.996	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.004	0.996	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.004	0.996	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.004	0.996	0.000
S71.1 Open wound of thigh	0.004	0.996	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.996	0.004
I08.9 Multiple valve disease, unspecified	0.000	0.996	0.004
K62.6 Ulcer of anus and rectum	0.004	0.996	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.996	0.004
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.996	0.004
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.996	0.004
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.996	0.004
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.996	0.004
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.996	0.004
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.996	0.004
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.996	0.004
C81.7 Other Hodgkin's disease	0.000	0.996	0.004
I15.8 Other secondary hypertension	0.000	0.996	0.004
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
M65.29 Calcific tendinitis (Site unspecified)	0.000	0.996	0.004
M65.28 Calcific tendinitis (Other)	0.000	0.996	0.004
M65.27 Calcific tendinitis (Ankle and foot)	0.000	0.996	0.004
M65.26 Calcific tendinitis (Lower leg)	0.000	0.996	0.004
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.000	0.996	0.004
M65.24 Calcific tendinitis (Hand)	0.000	0.996	0.004
M65.23 Calcific tendinitis (Forearm)	0.000	0.996	0.004
M65.22 Calcific tendinitis (Upper arm)	0.000	0.996	0.004
M65.20 Calcific tendinitis (Multiple sites)	0.000	0.996	0.004
H00.1 Chalazion	0.004	0.996	0.000
S75.0 Injury of femoral artery	0.004	0.996	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.996	0.004
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.996	0.004
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.996	0.004
C81.3 Lymphocytic depletion	0.000	0.996	0.004
M65.21 Calcific tendinitis (Shoulder region)	0.000	0.996	0.004
S73.0 Dislocation of hip	0.004	0.996	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.996	0.004
C81.2 Mixed cellularity	0.000	0.996	0.004
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.004	0.996	0.000
I15.2 Hypertension secondary to endocrine disorders	0.000	0.996	0.004
I05-I09 Chronic rheumatic heart diseases	0.000	0.996	0.004
J02 Acute pharyngitis	0.000	0.996	0.004
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.996	0.003
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.996	0.003
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.996	0.003
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.996	0.003
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.996	0.003
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.996	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.996	0.004
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.996	0.003
H04.1 Other disorders of lachrymal gland	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.000	0.996	0.004
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.997	0.003
H35.0 Background retinopathy and retinal vascular changes	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.000	0.997	0.003
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.997	0.003
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.003	0.997	0.000
S70.0 Contusion of hip	0.003	0.997	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.997	0.003
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003
I07.0 Tricuspid stenosis	0.000	0.997	0.003
I50.0 Congestive heart failure	0.000	0.997	0.003
I27.0 Primary pulmonary hypertension	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.000	0.997	0.003
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.997	0.003
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I27 Other pulmonary heart diseases	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
J02.0 Streptococcal pharyngitis	0.000	0.997	0.003
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.997	0.003
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.003
L50.9 Urticaria, unspecified	0.003	0.997	0.000
O21.2 Late vomiting of pregnancy	0.000	0.997	0.003
I09 Other rheumatic heart diseases	0.000	0.997	0.003
O26.9 Pregnancy-related condition, unspecified	0.000	0.997	0.003
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.997	0.003
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.997	0.003
O14.1 Severe preeclampsia	0.000	0.997	0.003
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.997	0.003
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.997	0.003
I06 Rheumatic aortic valve diseases	0.000	0.997	0.002
I27.8 Other specified pulmonary heart diseases	0.000	0.997	0.003
O12.1 Gestational proteinuria	0.000	0.997	0.003
L84 Corns and callosities	0.003	0.997	0.000
H35.7 Separation of retinal layers	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.997	0.003
O21 Excessive vomiting in pregnancy	0.000	0.997	0.003
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I50 Heart failure	0.000	0.997	0.003
H35.8 Other specified retinal disorders	0.003	0.997	0.000
L51.1 Bullous erythema multiforme	0.002	0.997	0.000
O16 Unspecified maternal hypertension	0.000	0.997	0.003
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.997	0.003
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.997	0.002
H35 Other retinal disorders	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
L51.9 Erythema multiforme, unspecified	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.002
O15 Eclampsia	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
L51 Erythema multiforme	0.002	0.998	0.000
C21.0 Anus, unspecified	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
H00 Hordeolum and chalazion	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.998	0.002
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.998	0.002
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E10-E14 Diabetes mellitus	0.000	0.998	0.002
I50.1 Left ventricular failure	0.000	0.998	0.002
O26.2 Pregnancy care of habitual aborter	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I30-I52 Other forms of heart disease	0.000	0.998	0.002
H00.0 Hordeolum and other deep inflammation of eyelid	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.998	0.002
O14.2 HELLP syndrome	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
L50 Urticaria	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.998	0.002
O25 Malnutrition in pregnancy	0.000	0.998	0.002
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
L53.8 Other specified erythematous conditions	0.002	0.998	0.000
O26.5 Maternal hypotension syndrome	0.000	0.998	0.002
O22 Venous complications in pregnancy	0.000	0.998	0.002
E13 Other specified diabetes mellitus	0.000	0.998	0.002
D30.3 Bladder	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E13.9 Without complications	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.002	0.998	0.000
O26.4 Herpes gestationis	0.000	0.998	0.002
O26.1 Low weight gain in pregnancy	0.000	0.998	0.002
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.998	0.002
S22 Fracture of rib(s), sternum and thoracic spine	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.998	0.002
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.998	0.002
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.998	0.002
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.998	0.002
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.998	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.998	0.002
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.000	0.998	0.002
O15.1 Eclampsia in labour	0.000	0.998	0.002
O15.0 Eclampsia in pregnancy	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
I40 Acute myocarditis	0.000	0.998	0.002
L51.8 Other erythema multiforme	0.002	0.998	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.002	0.998	0.000
L51.0 Nonbullous erythema multiforme	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.000	0.998	0.002
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.998	0.002
H35.5 Hereditary retinal dystrophy	0.002	0.998	0.000
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
R23.4 Changes in skin texture	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.002
E12 Malnutrition-related diabetes mellitus	0.000	0.998	0.002
I42 Cardiomyopathy	0.000	0.998	0.002
M65-M68 Disorders of synovium and tendon	0.000	0.998	0.002
Chapter IX Diseases of the circulatory system	0.000	0.998	0.002
I30.1 Infective pericarditis	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.998	0.002
I48 Atrial fibrillation and flutter	0.000	0.998	0.002
I41 Myocarditis in diseases classified elsewhere	0.000	0.998	0.002
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I32 Pericarditis in diseases classified elsewhere	0.000	0.998	0.002
I30 Acute pericarditis	0.000	0.998	0.002
L50-L54 Urticaria and erythema	0.002	0.998	0.000
I40.0 Infective myocarditis	0.000	0.998	0.002
O20.0 Threatened abortion	0.000	0.998	0.002
O22.1 Genital varices in pregnancy	0.000	0.998	0.002
I05.0 Mitral stenosis	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.998	0.002
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
L50.8 Other urticaria	0.002	0.998	0.000
O12.0 Gestational oedema	0.000	0.998	0.002
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.998	0.002
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.6 Failed or difficult intubation during pregnancy	0.000	0.998	0.002
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.998	0.002
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.998	0.002
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.998	0.002
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.998	0.002
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.998	0.002
H35.2 Other proliferative retinopathy	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.998	0.002
O22.8 Other venous complications in pregnancy	0.000	0.998	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.998	0.002
O22.4 Haemorrhoids in pregnancy	0.000	0.998	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.998	0.002
O26.0 Excessive weight gain in pregnancy	0.000	0.998	0.002
L53 Other erythematous conditions	0.002	0.998	0.000
E13.8 With unspecified complications	0.000	0.998	0.002
E13.7 With multiple complications	0.000	0.998	0.002
E13.6 With other specified complications	0.000	0.998	0.002
E13.5 With peripheral circulatory complications	0.000	0.998	0.002
E13.4 With neurological complications	0.000	0.998	0.002
E13.2 With renal complications	0.000	0.998	0.002
E13.1 With ketoacidosis	0.000	0.998	0.002
E13.0 With coma	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
E13.3 With ophthalmic complications	0.000	0.998	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.002	0.998	0.000
L53.0 Toxic erythema	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.998	0.002
S22.5 Flail chest	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.998	0.002
S22.9 Fracture of bony thorax, part unspecified	0.002	0.998	0.000
S22.8 Fracture of other parts of bony thorax	0.002	0.998	0.000
G58 Other mononeuropathies	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
R29.6 Tendency to fall, not elsewhere classified	0.002	0.998	0.000
H81 Disorders of vestibular function	0.000	0.998	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.000	0.998	0.001
I40.8 Other acute myocarditis	0.000	0.998	0.002
I40.1 Isolated myocarditis	0.000	0.998	0.002
W29.9 Unspecified place	0.002	0.998	0.000
I28 Other diseases of pulmonary vessels	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
I40.9 Acute myocarditis, unspecified	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
G58.7 Mononeuritis multiplex	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
O87.2 Haemorrhoids in the puerperium	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
O97 Death from sequelae of direct obstetric causes	0.000	0.998	0.002
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.998	0.002
O95 Obstetric death of unspecified cause	0.000	0.998	0.002
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.998	0.002
E12.9 Without complications	0.000	0.998	0.001
E12.8 With unspecified complications	0.000	0.998	0.001
E12.7 With multiple complications	0.000	0.998	0.001
E12.6 With other specified complications	0.000	0.998	0.001
E12.5 With peripheral circulatory complications	0.000	0.998	0.001
E12.4 With neurological complications	0.000	0.998	0.001
E12.3 With ophthalmic complications	0.000	0.998	0.001
E12.2 With renal complications	0.000	0.998	0.001
E12.1 With ketoacidosis	0.000	0.998	0.001
E12.0 With coma	0.000	0.998	0.001
G58.0 Intercostal neuropathy	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.998	0.001
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.998	0.000
H35.4 Peripheral retinal degeneration	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.001
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.998	0.001
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.998	0.001
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.998	0.001
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.998	0.001
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.998	0.001
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.998	0.001
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.998	0.001
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.998	0.001
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.998	0.001
I48.4 Atypical atrial flutter	0.000	0.998	0.001
I48.3 Typical atrial flutter	0.000	0.998	0.001
I48.2 Chronic atrial fibrillation	0.000	0.998	0.001
I48.1 Persistent atrial fibrillation	0.000	0.998	0.001
I48.0 Paroxysmal atrial fibrillation	0.000	0.998	0.001
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations