TreeWAS – Variant ID: rs17727296

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
I30-I52 Other forms of heart disease	0.999	0.001	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.996	0.004	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.995	0.005	0.000
M50-M54 Other dorsopathies	0.992	0.008	0.000
T81 Complications of procedures, not elsewhere classified	0.986	0.014	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.979	0.021	0.000
I45 Other conduction disorders	0.976	0.024	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.976	0.024	0.000
M54 Dorsalgia	0.973	0.027	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.973	0.027	0.000
E65-E68 Obesity and other hyperalimentation	0.967	0.033	0.000
Chapter II Neoplasms	0.967	0.033	0.000
G90-G99 Other disorders of the nervous system	0.964	0.036	0.000
E66 Obesity	0.961	0.039	0.000
E66.9 Obesity, unspecified	0.960	0.040	0.000
I51 Complications and ill-defined descriptions of heart disease	0.954	0.046	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.951	0.049	0.000
I20-I25 Ischaemic heart diseases	0.950	0.050	0.000
I46 Cardiac arrest	0.949	0.051	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.948	0.052	0.000
I47 Paroxysmal tachycardia	0.948	0.052	0.000
O60-O75 Complications of labour and delivery	0.946	0.054	0.000
I45.1 Other and unspecified right bundle-branch block	0.945	0.055	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.944	0.056	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.941	0.059	0.000
M70-M79 Other soft tissue disorders	0.929	0.071	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.925	0.075	0.000
Chapter V Mental and behavioural disorders	0.924	0.076	0.000
I47.2 Ventricular tachycardia	0.920	0.080	0.000
I25 Chronic ischaemic heart disease	0.914	0.086	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.911	0.089	0.000
M51 Other intervertebral disk disorders	0.910	0.090	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.910	0.090	0.000
Chapter I Certain infectious and parasitic diseases	0.909	0.091	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.907	0.093	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.898	0.102	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.898	0.102	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.895	0.105	0.000
I51.7 Cardiomegaly	0.893	0.107	0.000
I46.0 Cardiac arrest with successful resuscitation	0.892	0.108	0.000
I25.1 Atherosclerotic heart disease	0.889	0.111	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.889	0.111	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.888	0.112	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.886	0.114	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.884	0.116	0.000
I60-I69 Cerebrovascular diseases	0.879	0.121	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.879	0.121	0.000
D69 Purpura and other haemorrhagic conditions	0.878	0.122	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.878	0.122	0.000
M54.9 Dorsalgia, unspecified	0.877	0.123	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.867	0.133	0.000
C71 Malignant neoplasm of brain	0.865	0.135	0.000
I49 Other cardiac arrhythmias	0.865	0.135	0.000
B35-B49 Mycoses	0.863	0.137	0.000
Chapter XX External causes of morbidity and mortality	0.861	0.139	0.000
M54.1 Radiculopathy	0.861	0.139	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.859	0.141	0.000
S20-S29 Injuries to the thorax	0.858	0.142	0.000
I05-I09 Chronic rheumatic heart diseases	0.855	0.145	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.853	0.147	0.000
D60-D64 Aplastic and other anaemias	0.851	0.149	0.000
E40-E46 Malnutrition	0.849	0.150	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.847	0.153	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.844	0.156	0.000
O80-O84 Delivery	0.841	0.159	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.840	0.160	0.000
S90-S99 Injuries to the ankle and foot	0.835	0.165	0.000
O32.0 Maternal care for unstable lie	0.834	0.166	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.832	0.167	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.832	0.168	0.000
S10-S19 Injuries to the neck	0.832	0.168	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.831	0.169	0.000
C51-C58 Malignant neoplasms of female genital organs	0.828	0.172	0.000
S70-S79 Injuries to the hip and thigh	0.826	0.174	0.000
G57 Mononeuropathies of lower limb	0.826	0.174	0.000
I22 Subsequent myocardial infarction	0.823	0.177	0.000
I33 Acute and subacute endocarditis	0.818	0.181	0.000
A30-A49 Other bacterial diseases	0.817	0.183	0.000
I60 Subarachnoid haemorrhage	0.816	0.184	0.000
M79.6 Pain in limb	0.816	0.184	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.815	0.185	0.000
S80-S89 Injuries to the knee and lower leg	0.814	0.186	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.811	0.189	0.000
B37 Candidiasis	0.811	0.189	0.000
M50 Cervical disk disorders	0.810	0.190	0.000
M05-M14 Inflammatory polyarthropathies	0.809	0.191	0.000
M51.2 Other specified intervertebral disk displacement	0.808	0.192	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.806	0.194	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.806	0.194	0.000
D69.6 Thrombocytopenia, unspecified	0.805	0.195	0.000
S40-S49 Injuries to the shoulder and upper arm	0.804	0.196	0.000
I51.8 Other ill-defined heart diseases	0.803	0.197	0.000
S00-S09 Injuries to the head	0.803	0.197	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.802	0.198	0.000
O16 Unspecified maternal hypertension	0.802	0.198	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.801	0.199	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.801	0.199	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.799	0.201	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.798	0.202	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.797	0.203	0.000
M54.5 Low back pain	0.797	0.203	0.000
Chapter X Diseases of the respiratory system	0.796	0.204	0.000
I05 Rheumatic mitral valve diseases	0.796	0.204	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.795	0.205	0.000
S50-S59 Injuries to the elbow and forearm	0.795	0.205	0.000
I45.6 Preexcitation syndrome	0.794	0.206	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.794	0.206	0.000
G03 Meningitis due to other and unspecified causes	0.791	0.209	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.791	0.209	0.000
M40-M43 Deforming dorsopathies	0.788	0.212	0.000
C15-C26 Malignant neoplasms of digestive organs	0.787	0.213	0.000
T79-T79 Certain early complications of trauma	0.787	0.213	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.786	0.214	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.785	0.215	0.000
M54.3 Sciatica	0.783	0.217	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.782	0.218	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.781	0.219	0.000
I49.0 Ventricular fibrillation and flutter	0.781	0.219	0.000
G95 Other diseases of spinal cord	0.780	0.220	0.000
I46.9 Cardiac arrest, unspecified	0.780	0.220	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.779	0.220	0.000
O47 False labour	0.779	0.221	0.000
C56 Malignant neoplasm of ovary	0.776	0.224	0.000
I45.9 Conduction disorder, unspecified	0.775	0.225	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.773	0.227	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.772	0.227	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.770	0.229	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.770	0.230	0.000
D80-D89 Certain disorders involving the immune mechanism	0.770	0.230	0.000
O72 Postpartum haemorrhage	0.770	0.230	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.767	0.233	0.000
J90-J94 Other diseases of pleura	0.767	0.233	0.000
I42 Cardiomyopathy	0.766	0.234	0.000
M86-M90 Other osteopathies	0.765	0.234	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.765	0.234	0.000
G30-G32 Other degenerative diseases of the nervous system	0.763	0.237	0.000
Chapter XXI Factors influencing health status and contact with health services	0.763	0.237	0.000
I51.0 Cardiac septal defect, acquired	0.761	0.239	0.000
B37.8 Candidiasis of other sites	0.760	0.240	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.759	0.241	0.000
E46 Unspecified protein-energy malnutrition	0.759	0.241	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.759	0.241	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.758	0.242	0.000
C71.1 Frontal lobe	0.758	0.242	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.756	0.244	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.755	0.245	0.000
M15-M19 Arthrosis	0.755	0.245	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.755	0.245	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.755	0.245	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.754	0.246	0.000
I25.5 Ischaemic cardiomyopathy	0.753	0.246	0.000
S20 Superficial injury of thorax	0.753	0.247	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.753	0.247	0.000
Q60-Q64 Congenital malformations of the urinary system	0.753	0.247	0.000
G91 Hydrocephalus	0.752	0.247	0.000
I61 Intracerebral haemorrhage	0.751	0.249	0.000
D55-D59 Haemolytic anaemias	0.749	0.250	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.748	0.252	0.000
I49.3 Ventricular premature depolarisation	0.747	0.252	0.000
O85-O92 Complications predominantly related to the puerperium	0.747	0.253	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.745	0.255	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.745	0.255	0.000
T86 Failure and rejection of transplanted organs and tissues	0.744	0.256	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.743	0.257	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.743	0.257	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.742	0.257	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.742	0.258	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.741	0.259	0.000
G57.6 Lesion of plantar nerve	0.741	0.259	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.740	0.260	0.000
G20-G26 Extrapyramidal and movement disorders	0.740	0.260	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.739	0.261	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.738	0.262	0.000
I35 Nonrheumatic aortic valve disorders	0.738	0.262	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.737	0.263	0.000
W20-W49 Exposure to inanimate mechanical forces	0.737	0.263	0.000
C71.9 Brain, unspecified	0.737	0.263	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.736	0.264	0.000
D46 Myelodysplastic syndromes	0.735	0.265	0.000
T90 Sequelae of injuries of head	0.734	0.266	0.000
M54.12 Radiculopathy (Cervical region)	0.731	0.269	0.000
M54.2 Cervicalgia	0.730	0.270	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.729	0.271	0.000
O43 Placental disorders	0.729	0.271	0.000
S81 Open wound of lower leg	0.728	0.272	0.000
I30 Acute pericarditis	0.727	0.273	0.000
S30.0 Contusion of lower back and pelvis	0.725	0.275	0.000
M00-M03 Infectious arthropathies	0.724	0.276	0.000
G51 Facial nerve disorders	0.722	0.278	0.000
O80 Single spontaneous delivery	0.721	0.279	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.721	0.279	0.000
I05.9 Mitral valve disease, unspecified	0.721	0.279	0.000
M54.4 Lumbago with sciatica	0.719	0.281	0.000
D63.0 Anaemia in neoplastic disease	0.717	0.283	0.000
A49 Bacterial infection of unspecified site	0.717	0.283	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.716	0.283	0.000
I48 Atrial fibrillation and flutter	0.716	0.283	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.283	0.000
I41 Myocarditis in diseases classified elsewhere	0.716	0.283	0.000
I40 Acute myocarditis	0.716	0.283	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.283	0.000
I37 Pulmonary valve disorders	0.716	0.283	0.000
I36 Nonrheumatic tricuspid valve disorders	0.716	0.283	0.000
I32 Pericarditis in diseases classified elsewhere	0.716	0.283	0.000
M54.6 Pain in thoracic spine	0.716	0.284	0.000
C71.0 Cerebrum, except lobes and ventricles	0.715	0.285	0.000
M60-M63 Disorders of muscles	0.715	0.285	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.714	0.286	0.000
O44 Placenta praevia	0.714	0.286	0.000
M54.56 Low back pain (Lumbar region)	0.714	0.286	0.000
T87 Complications peculiar to reattachment and amputation	0.713	0.287	0.000
F10.2 Dependence syndrome	0.713	0.287	0.000
M79.1 Myalgia	0.713	0.287	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.712	0.288	0.000
S30.1 Contusion of abdominal wall	0.712	0.288	0.000
T91 Sequelae of injuries of neck and trunk	0.711	0.289	0.000
M54.16 Radiculopathy (Lumbar region)	0.711	0.289	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.711	0.289	0.000
S80 Superficial injury of lower leg	0.711	0.289	0.000
S06 Intracranial injury	0.710	0.289	0.000
T88.5 Other complications of anaesthesia	0.710	0.290	0.000
G57.8 Other mononeuropathies of lower limb	0.710	0.290	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.709	0.291	0.000
B49 Unspecified mycosis	0.708	0.292	0.000
F10.3 Withdrawal state	0.707	0.293	0.000
G93 Other disorders of brain	0.707	0.293	0.000
T81.9 Unspecified complication of procedure	0.707	0.293	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.707	0.293	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.707	0.293	0.000
G96 Other disorders of central nervous system	0.706	0.293	0.000
M79.5 Residual foreign body in soft tissue	0.706	0.294	0.000
D68 Other coagulation defects	0.705	0.295	0.000
B99-B99 Other infectious diseases	0.705	0.295	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.704	0.296	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.296	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.703	0.297	0.000
M79.66 Pain in limb (Lower leg)	0.703	0.297	0.000
D70 Agranulocytosis	0.703	0.297	0.000
T98 Sequelae of other and unspecified effects of external causes	0.702	0.298	0.000
O73 Retained placenta and membranes, without haemorrhage	0.701	0.299	0.000
O26.8 Other specified pregnancy-related conditions	0.701	0.299	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.701	0.299	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.700	0.300	0.000
I45.8 Other specified conduction disorders	0.700	0.300	0.000
I45.4 Nonspecific intraventricular block	0.700	0.300	0.000
I45.3 Trifascicular block	0.700	0.300	0.000
I45.2 Bifascicular block	0.700	0.300	0.000
I45.0 Right fascicular block	0.700	0.300	0.000
O61 Failed induction of labour	0.700	0.300	0.000
C78.7 Secondary malignant neoplasm of liver	0.699	0.301	0.000
M54.8 Other dorsalgia	0.698	0.302	0.000
M54.0 Panniculitis affecting regions of neck and back	0.698	0.302	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.698	0.302	0.000
J09-J18 Influenza and pneumonia	0.698	0.302	0.000
G61 Inflammatory polyneuropathy	0.697	0.303	0.000
E00-E07 Disorders of thyroid gland	0.697	0.303	0.000
Chapter XXII Codes for special purposes	0.696	0.303	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304	0.000
M05 Seropositive rheumatoid arthritis	0.696	0.304	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.695	0.305	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.695	0.305	0.000
O42 Premature rupture of membranes	0.695	0.305	0.000
E67 Other hyperalimentation	0.693	0.306	0.000
E68 Sequelae of hyperalimentation	0.693	0.306	0.000
E65 Localised adiposity	0.693	0.306	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.693	0.307	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.691	0.309	0.000
G90 Disorders of autonomic nervous system	0.691	0.309	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.691	0.309	0.000
G92 Toxic encephalopathy	0.691	0.309	0.000
M91-M94 Chondropathies	0.691	0.309	0.000
T66-T78 Other and unspecified effects of external causes	0.689	0.310	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.689	0.311	0.000
E66.1 Drug-induced obesity	0.689	0.311	0.000
E66.0 Obesity due to excess calories	0.689	0.311	0.000
I33.0 Acute and subacute infective endocarditis	0.689	0.311	0.000
M53 Other dorsopathies, not elsewhere classified	0.689	0.311	0.000
T92 Sequelae of injuries of upper limb	0.689	0.311	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.688	0.312	0.000
O00-O08 Pregnancy with abortive outcome	0.687	0.312	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.687	0.313	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.687	0.313	0.000
Z60 Problems related to social environment	0.686	0.313	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.686	0.314	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.686	0.314	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.685	0.315	0.000
M65-M68 Disorders of synovium and tendon	0.684	0.316	0.000
G50 Disorders of trigeminal nerve	0.684	0.316	0.000
I51.6 Cardiovascular disease, unspecified	0.684	0.316	0.000
I51.5 Myocardial degeneration	0.684	0.316	0.000
I51.4 Myocarditis, unspecified	0.684	0.316	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.684	0.316	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.684	0.316	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.684	0.316	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.682	0.317	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.682	0.318	0.000
I23 Certain current complications following acute myocardial infarction	0.681	0.319	0.000
G03.9 Meningitis, unspecified	0.681	0.319	0.000
I46.1 Sudden cardiac death, so described	0.681	0.319	0.000
O48 Prolonged pregnancy	0.680	0.320	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.680	0.320	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.680	0.320	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.680	0.320	0.000
S37 Injury of urinary and pelvic organs	0.680	0.320	0.000
S36 Injury of intra-abdominal organs	0.680	0.320	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.680	0.320	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.680	0.320	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.680	0.320	0.000
S31 Open wound of abdomen, lower back and pelvis	0.680	0.320	0.000
I47.0 Reentry ventricular arrhythmia	0.679	0.320	0.000
Q80-Q89 Other congenital malformations	0.679	0.321	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.679	0.321	0.000
S29 Other and unspecified injuries of thorax	0.679	0.321	0.000
J90 Pleural effusion, not elsewhere classified	0.679	0.321	0.000
F43 Reaction to severe stress, and adjustment disorders	0.679	0.321	0.000
C91 Lymphoid leukaemia	0.678	0.321	0.000
O74 Complications of anaesthesia during labour and delivery	0.678	0.322	0.000
O71 Other obstetric trauma	0.678	0.322	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.678	0.322	0.000
O60 Preterm delivery	0.678	0.322	0.000
I20 Angina pectoris	0.678	0.322	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.677	0.323	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.677	0.323	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.677	0.323	0.000
G00 Bacterial meningitis, not elsewhere classified	0.677	0.323	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.677	0.323	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.677	0.323	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.677	0.323	0.000
D62 Acute posthaemorrhagic anaemia	0.676	0.324	0.000
M79.69 Pain in limb (Site unspecified)	0.676	0.324	0.000
F80-F89 Disorders of psychological development	0.676	0.324	0.000
M79.2 Neuralgia and neuritis, unspecified	0.676	0.324	0.000
E70-E90 Metabolic disorders	0.675	0.325	0.000
Q43 Other congenital malformations of intestine	0.675	0.325	0.000
O45 Premature separation of placenta [abruptio placentae]	0.675	0.325	0.000
O33 Maternal care for known or suspected disproportion	0.675	0.325	0.000
O31 Complications specific to multiple gestation	0.675	0.325	0.000
O40 Polyhydramnios	0.675	0.325	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.673	0.327	0.000
I24 Other acute ischaemic heart diseases	0.673	0.327	0.000
O26.9 Pregnancy-related condition, unspecified	0.673	0.327	0.000
C01 Malignant neoplasm of base of tongue	0.672	0.328	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.672	0.328	0.000
M79.8 Other specified soft tissue disorders	0.671	0.329	0.000
T51 Toxic effect of alcohol	0.670	0.329	0.000
F10.0 Acute intoxication	0.670	0.329	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.670	0.330	0.000
O62 Abnormalities of forces of labour	0.669	0.331	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.668	0.332	0.000
M79.67 Pain in limb (Ankle and foot)	0.668	0.332	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.668	0.332	0.000
O41 Other disorders of amniotic fluid and membranes	0.668	0.332	0.000
I05.0 Mitral stenosis	0.667	0.333	0.000
O32.1 Maternal care for breech presentation	0.667	0.333	0.000
M76 Enthesopathies of lower limb, excluding foot	0.666	0.334	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.666	0.334	0.000
A41 Other septicaemia	0.666	0.334	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.665	0.334	0.000
I45.5 Other specified heart block	0.665	0.335	0.000
D69.5 Secondary thrombocytopenia	0.664	0.336	0.000
M50.1 Cervical disk disorder with radiculopathy	0.664	0.336	0.000
D67 Hereditary factor IX deficiency	0.663	0.337	0.000
D66 Hereditary factor VIII deficiency	0.663	0.337	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.663	0.337	0.000
G70-G73 Diseases of myoneural junction and muscle	0.663	0.337	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.663	0.337	0.000
F70-F79 Mental retardation	0.663	0.337	0.000
M80-M85 Disorders of bone density and structure	0.659	0.338	0.003
S20.8 Superficial injuries of other and unspecified parts of thorax	0.662	0.338	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.662	0.338	0.000
S51 Open wound of forearm	0.662	0.338	0.000
I63 Cerebral infarction	0.660	0.340	0.000
D72 Other disorders of white blood cells	0.659	0.341	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.659	0.341	0.000
M79.60 Pain in limb (Multiple sites)	0.659	0.341	0.000
M70.6 Trochanteric bursitis	0.659	0.341	0.000
G62 Other polyneuropathies	0.658	0.342	0.000
C25 Malignant neoplasm of pancreas	0.658	0.342	0.000
T56 Toxic effect of metals	0.658	0.342	0.000
B15-B19 Viral hepatitis	0.658	0.342	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.658	0.342	0.000
T93 Sequelae of injuries of lower limb	0.657	0.343	0.000
Q00-Q07 Congenital malformations of the nervous system	0.656	0.344	0.000
G95.8 Other specified diseases of spinal cord	0.656	0.344	0.000
Z60.2 Living alone	0.656	0.344	0.000
I25.6 Silent myocardial ischaemia	0.655	0.345	0.000
I25.4 Coronary artery aneurysm	0.655	0.345	0.000
I25.3 Aneurysm of heart	0.655	0.345	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.655	0.345	0.000
O36 Maternal care for other known or suspected foetal problems	0.655	0.345	0.000
C79 Secondary malignant neoplasm of other sites	0.654	0.346	0.000
D43.2 Brain, unspecified	0.654	0.346	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.654	0.346	0.000
J91 Pleural effusion in conditions classified elsewhere	0.653	0.346	0.000
G51.9 Disorder of facial nerve, unspecified	0.653	0.347	0.000
S72 Fracture of femur	0.653	0.347	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.653	0.347	0.000
S30.2 Contusion of external genital organs	0.653	0.347	0.000
M75 Shoulder lesions	0.653	0.347	0.000
M51.3 Other specified intervertebral disk degeneration	0.653	0.347	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.653	0.347	0.000
M51.4 Schmorl's nodes	0.653	0.347	0.000
D61 Other aplastic anaemias	0.653	0.347	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.652	0.347	0.000
Q35-Q37 Cleft lip and cleft palate	0.652	0.347	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.652	0.347	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.652	0.347	0.000
G54 Nerve root and plexus disorders	0.652	0.347	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.652	0.348	0.000
B65-B83 Helminthiases	0.652	0.348	0.000
B50-B64 Protozoal diseases	0.652	0.348	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.652	0.348	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.652	0.348	0.000
A75-A79 Rickettsioses	0.652	0.348	0.000
A70-A74 Other diseases caused by chlamydiae	0.652	0.348	0.000
A65-A69 Other spirochaetal diseases	0.652	0.348	0.000
A20-A28 Certain zoonotic bacterial diseases	0.652	0.348	0.000
A15-A19 Tuberculosis	0.652	0.348	0.000
J60-J70 Lung diseases due to external agents	0.652	0.348	0.000
F10.1 Harmful use	0.651	0.349	0.000
S70 Superficial injury of hip and thigh	0.651	0.349	0.000
I34 Nonrheumatic mitral valve disorders	0.651	0.349	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.651	0.349	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.651	0.349	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.651	0.349	0.000
C71.2 Temporal lobe	0.651	0.349	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.650	0.350	0.000
C70 Malignant neoplasm of meninges	0.650	0.350	0.000
D73 Diseases of spleen	0.650	0.350	0.000
C10 Malignant neoplasm of oropharynx	0.649	0.351	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.648	0.352	0.000
T39.0 Salicylates	0.647	0.353	0.000
J93 Pneumothorax	0.647	0.353	0.000
S92 Fracture of foot, except ankle	0.647	0.353	0.000
S14 Injury of nerves and spinal cord at neck level	0.646	0.354	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.646	0.354	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.646	0.354	0.000
M71 Other bursopathies	0.645	0.355	0.000
M15 Polyarthrosis	0.645	0.355	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.644	0.356	0.000
M43 Other deforming dorsopathies	0.644	0.356	0.000
T95 Sequelae of burns, corrosions and frostbite	0.644	0.356	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.644	0.356	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.644	0.356	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.644	0.356	0.000
S32 Fracture of lumbar spine and pelvis	0.644	0.356	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.644	0.356	0.000
O15 Eclampsia	0.644	0.356	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.644	0.356	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.644	0.356	0.000
C21 Malignant neoplasm of anus and anal canal	0.643	0.357	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.643	0.357	0.000
C69 Malignant neoplasm of eye and adnexa	0.643	0.357	0.000
O24 Diabetes mellitus in pregnancy	0.643	0.357	0.000
M51.9 Intervertebral disk disorder, unspecified	0.643	0.357	0.000
C64-C68 Malignant neoplasms of urinary tract	0.642	0.358	0.000
D86 Sarcoidosis	0.642	0.358	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.642	0.358	0.000
I50 Heart failure	0.642	0.358	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.641	0.359	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.640	0.360	0.000
M06 Other rheumatoid arthritis	0.640	0.360	0.000
Q50-Q56 Congenital malformations of genital organs	0.640	0.360	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.639	0.361	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.638	0.362	0.000
M79.9 Soft tissue disorder, unspecified	0.637	0.363	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.637	0.363	0.000
M79.3 Panniculitis, unspecified	0.637	0.363	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.637	0.363	0.000
T88.9 Complication of surgical and medical care, unspecified	0.637	0.363	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.637	0.363	0.000
T88.2 Shock due to anaesthesia	0.637	0.363	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.637	0.363	0.000
T88.0 Infection following immunisation	0.637	0.363	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.636	0.364	0.000
C32 Malignant neoplasm of larynx	0.636	0.364	0.000
B37.0 Candidal stomatitis	0.636	0.364	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.635	0.365	0.000
O32.8 Maternal care for other malpresentation of foetus	0.635	0.365	0.000
O32.6 Maternal care for compound presentation	0.635	0.365	0.000
O32.4 Maternal care for high head at term	0.635	0.365	0.000
O32.3 Maternal care for face, brow and chin presentation	0.635	0.365	0.000
O32.2 Maternal care for transverse and oblique lie	0.635	0.365	0.000
C18 Malignant neoplasm of colon	0.634	0.366	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.634	0.366	0.000
A80-A89 Viral infections of the central nervous system	0.634	0.366	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.634	0.366	0.000
G52 Disorders of other cranial nerves	0.634	0.366	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations