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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1801177
log Bayes Factor = 13.37
Chromosome 8   position 19,805,708  (GRCh37) Explore rs1801177 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
I21 Acute myocardial infarction
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.989 0.011 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.989 0.011 0.000
I25.1 Atherosclerotic heart disease
0.986 0.014 0.000
E78.5 Hyperlipidaemia, unspecified
0.981 0.019 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
M50-M54 Other dorsopathies
0.970 0.030 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.967 0.033 0.000
M51 Other intervertebral disk disorders
0.964 0.036 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.963 0.037 0.000
I73 Other peripheral vascular diseases
0.963 0.037 0.000
I20 Angina pectoris
0.963 0.037 0.000
M51.2 Other specified intervertebral disk displacement
0.958 0.042 0.000
I20.0 Unstable angina
0.955 0.045 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.947 0.053 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.945 0.055 0.000
I73.9 Peripheral vascular disease, unspecified
0.944 0.056 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.939 0.061 0.000
I30-I52 Other forms of heart disease
0.923 0.077 0.000
Chapter V Mental and behavioural disorders
0.911 0.089 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.910 0.090 0.000
S60-S69 Injuries to the wrist and hand
0.907 0.093 0.000
Chapter XX External causes of morbidity and mortality
0.907 0.093 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.903 0.097 0.000
R00 Abnormalities of heart beat
0.893 0.107 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.890 0.110 0.000
R07 Pain in throat and chest
0.888 0.112 0.000
S00-S09 Injuries to the head
0.879 0.121 0.000
M54 Dorsalgia
0.876 0.124 0.000
E83 Disorders of mineral metabolism
0.872 0.128 0.000
I24 Other acute ischaemic heart diseases
0.870 0.130 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.866 0.134 0.000
I22 Subsequent myocardial infarction
0.866 0.134 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.864 0.136 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.860 0.140 0.000
T43.2 Other and unspecified antidepressants
0.857 0.143 0.000
R00.0 Tachycardia, unspecified
0.856 0.144 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.855 0.145 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.854 0.146 0.000
I71 Aortic aneurysm and dissection
0.853 0.147 0.000
R07.4 Chest pain, unspecified
0.851 0.149 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.850 0.150 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.848 0.152 0.000
I31 Other diseases of pericardium
0.846 0.154 0.000
I25.5 Ischaemic cardiomyopathy
0.846 0.154 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.840 0.160 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.839 0.161 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.837 0.163 0.000
I60-I69 Cerebrovascular diseases
0.836 0.164 0.000
S61 Open wound of wrist and hand
0.834 0.166 0.000
Chapter XI Diseases of the digestive system
0.831 0.169 0.000
F10.1 Harmful use
0.822 0.178 0.000
K50-K52 Noninfective enteritis and colitis
0.821 0.179 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.813 0.187 0.000
E78.0 Pure hypercholesterolaemia
0.812 0.188 0.000
Chapter VII Diseases of the eye and adnexa
0.810 0.190 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.805 0.195 0.000
I35 Nonrheumatic aortic valve disorders
0.804 0.196 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.801 0.198 0.000
K51 Ulcerative colitis
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
E20-E35 Disorders of other endocrine glands
0.797 0.203 0.000
E87.2 Acidosis
0.791 0.209 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.789 0.211 0.000
M54.3 Sciatica
0.788 0.211 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.788 0.212 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
R00.2 Palpitations
0.787 0.213 0.000
I31.9 Disease of pericardium, unspecified
0.786 0.214 0.000
I46 Cardiac arrest
0.785 0.215 0.000
S90-S99 Injuries to the ankle and foot
0.784 0.216 0.000
T79-T79 Certain early complications of trauma
0.784 0.216 0.000
M45-M49 Spondylopathies
0.783 0.217 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.780 0.220 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.778 0.222 0.000
R00.1 Bradycardia, unspecified
0.778 0.222 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.774 0.226 0.000
K70-K77 Diseases of liver
0.773 0.227 0.000
K51.9 Ulcerative colitis, unspecified
0.772 0.228 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.770 0.229 0.000
S61.0 Open wound of finger(s) without damage to nail
0.769 0.231 0.000
F10.2 Dependence syndrome
0.768 0.232 0.000
E87.5 Hyperkalaemia
0.768 0.232 0.000
K50 Crohn's disease [regional enteritis]
0.767 0.233 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.233 0.000
I74 Arterial embolism and thrombosis
0.766 0.234 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.764 0.235 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
E40-E46 Malnutrition
0.762 0.238 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.761 0.239 0.000
R94 Abnormal results of function studies
0.760 0.240 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.759 0.240 0.000
E78.8 Other disorders of lipoprotein metabolism
0.759 0.241 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.758 0.242 0.000
I25.3 Aneurysm of heart
0.758 0.242 0.000
M51.9 Intervertebral disk disorder, unspecified
0.758 0.242 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.758 0.242 0.000
I72 Other aneurysm
0.756 0.244 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
F60-F69 Disorders of adult personality and behaviour
0.753 0.247 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.752 0.248 0.000
T51 Toxic effect of alcohol
0.751 0.249 0.000
E50-E64 Other nutritional deficiencies
0.749 0.251 0.000
R07.3 Other chest pain
0.749 0.251 0.000
Chapter VIII Diseases of the ear and mastoid process
0.748 0.252 0.000
I77 Other disorders of arteries and arterioles
0.747 0.253 0.000
E83.1 Disorders of iron metabolism
0.746 0.254 0.000
I47 Paroxysmal tachycardia
0.743 0.257 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.742 0.258 0.000
R94.5 Abnormal results of liver function studies
0.740 0.260 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.731 0.268 0.000
K70 Alcoholic liver disease
0.731 0.269 0.000
S06 Intracranial injury
0.727 0.273 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.726 0.274 0.000
R07.0 Pain in throat
0.724 0.276 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.723 0.277 0.000
R27 Other lack of coordination
0.723 0.277 0.000
H53-H54 Visual disturbances and blindness
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.722 0.278 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.722 0.278 0.000
M86-M90 Other osteopathies
0.721 0.279 0.000
K90-K93 Other diseases of the digestive system
0.720 0.280 0.000
R25 Abnormal involuntary movements
0.720 0.280 0.000
E10-E14 Diabetes mellitus
0.719 0.280 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I21.9 Acute myocardial infarction, unspecified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M54.9 Dorsalgia, unspecified
0.716 0.284 0.000
E88 Other metabolic disorders
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
M54.39 Sciatica (Site unspecified)
0.712 0.287 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.711 0.288 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.711 0.288 0.000
I70 Atherosclerosis
0.711 0.289 0.000
I67 Other cerebrovascular diseases
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.709 0.291 0.000
R02 Gangrene, not elsewhere classified
0.709 0.291 0.000
E78.6 Lipoprotein deficiency
0.709 0.291 0.000
E78.4 Other hyperlipidaemia
0.709 0.291 0.000
E78.3 Hyperchylomicronaemia
0.709 0.291 0.000
E78.2 Mixed hyperlipidaemia
0.709 0.291 0.000
E78.1 Pure hyperglyceridaemia
0.709 0.291 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.708 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.708 0.292 0.000
I30 Acute pericarditis
0.704 0.295 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.702 0.298 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.700 0.300 0.000
S01 Open wound of head
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
E87.0 Hyperosmolality and hypernatraemia
0.698 0.302 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.697 0.303 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.696 0.304 0.000
S60 Superficial injury of wrist and hand
0.696 0.304 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
M51.3 Other specified intervertebral disk degeneration
0.691 0.308 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.691 0.308 0.000
M51.8 Other specified intervertebral disk disorders
0.691 0.308 0.000
M51.4 Schmorl's nodes
0.691 0.308 0.000
I73.0 Raynaud's syndrome
0.691 0.309 0.000
T43.9 Psychotropic drug, unspecified
0.691 0.309 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.691 0.309 0.000
T43.6 Psychostimulants with abuse potential
0.691 0.309 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.691 0.309 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.691 0.309 0.000
I73.8 Other specified peripheral vascular diseases
0.690 0.309 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.690 0.309 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.689 0.310 0.000
I49 Other cardiac arrhythmias
0.689 0.311 0.000
I62 Other nontraumatic intracranial haemorrhage
0.689 0.311 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.689 0.311 0.000
R07.2 Precordial pain
0.688 0.312 0.000
F99-F99 Unspecified mental disorder
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
I33 Acute and subacute endocarditis
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.684 0.316 0.000
E83.3 Disorders of phosphorus metabolism
0.683 0.317 0.000
V80-V89 Other land transport accidents
0.682 0.318 0.000
T93 Sequelae of injuries of lower limb
0.680 0.320 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.678 0.322 0.000
S62 Fracture at wrist and hand level
0.677 0.323 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.676 0.324 0.000
H80-H83 Diseases of inner ear
0.675 0.325 0.000
F10.4 Withdrawal state with delirium
0.675 0.325 0.000
E87.7 Fluid overload
0.674 0.326 0.000
H54 Blindness and low vision
0.674 0.326 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.673 0.326 0.000
E87.4 Mixed disorder of acid-base balance
0.673 0.326 0.000
E87.3 Alkalosis
0.673 0.326 0.000
Y52 Agents primarily affecting the cardiovascular system
0.674 0.326 0.000
M80-M85 Disorders of bone density and structure
0.673 0.327 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.672 0.328 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.668 0.332 0.000
K50.9 Crohn's disease, unspecified
0.668 0.332 0.000
F80-F89 Disorders of psychological development
0.668 0.332 0.000
S02 Fracture of skull and facial bones
0.666 0.333 0.000
I20.1 Angina pectoris with documented spasm
0.665 0.335 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
I46.9 Cardiac arrest, unspecified
0.662 0.338 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.662 0.338 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
I52 Other heart disorders in diseases classified elsewhere
0.662 0.338 0.000
I48 Atrial fibrillation and flutter
0.662 0.338 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.662 0.338 0.000
I41 Myocarditis in diseases classified elsewhere
0.662 0.338 0.000
I40 Acute myocarditis
0.662 0.338 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.662 0.338 0.000
I37 Pulmonary valve disorders
0.662 0.338 0.000
I36 Nonrheumatic tricuspid valve disorders
0.662 0.338 0.000
I32 Pericarditis in diseases classified elsewhere
0.662 0.338 0.000
F10.3 Withdrawal state
0.660 0.340 0.000
I24.8 Other forms of acute ischaemic heart disease
0.659 0.341 0.000
T51.9 Alcohol, unspecified
0.659 0.341 0.000
E65-E68 Obesity and other hyperalimentation
0.656 0.344 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.656 0.344 0.000
Y42.7 Androgens and anabolic congeners
0.655 0.345 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.653 0.347 0.000
F70-F79 Mental retardation
0.653 0.347 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.653 0.347 0.000
I95 Hypotension
0.652 0.348 0.000
W00-W19 Falls
0.651 0.349 0.000
S69 Other and unspecified injuries of wrist and hand
0.650 0.350 0.000
S67 Crushing injury of wrist and hand
0.650 0.350 0.000
S65 Injury of blood vessels at wrist and hand level
0.650 0.350 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.650 0.350 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.650 0.350 0.000
Y35-Y36 Legal intervention and operations of war
0.650 0.350 0.000
Y10-Y34 Event of undetermined intent
0.650 0.350 0.000
Y00-Y09 Assault
0.650 0.350 0.000
X85-X99 Assault
0.650 0.350 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.650 0.350 0.000
X50-X57 Overexertion, travel and privation
0.650 0.350 0.000
X30-X39 Exposure to forces of nature
0.650 0.350 0.000
X20-X29 Contact with venomous animals and plants
0.650 0.350 0.000
X10-X19 Contact with heat and hot substances
0.650 0.350 0.000
X00-X09 Exposure to smoke, fire and flames
0.650 0.350 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.650 0.350 0.000
W75-W84 Other accidental threats to breathing
0.650 0.350 0.000
W65-W74 Accidental drowning and submersion
0.650 0.350 0.000
W50-W64 Exposure to animate mechanical forces
0.650 0.350 0.000
V98-V99 Other and unspecified transport accidents
0.650 0.350 0.000
V95-V97 Air and space transport accidents
0.650 0.350 0.000
V90-V94 Water transport accidents
0.650 0.350 0.000
V70-V79 Bus occupant injured in transport accident
0.650 0.350 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.650 0.350 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.650 0.350 0.000
V40-V49 Car occupant injured in transport accident
0.650 0.350 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.650 0.350 0.000
V20-V29 Motorcycle rider injured in transport accident
0.650 0.350 0.000
V01-V09 Pedestrian injured in transport accident
0.650 0.350 0.000
M54.6 Pain in thoracic spine
0.650 0.350 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.648 0.352 0.000
Chapter XXI Factors influencing health status and contact with health services
0.647 0.353 0.000
S00 Superficial injury of head
0.647 0.353 0.000
I60 Subarachnoid haemorrhage
0.645 0.355 0.000
K70.9 Alcoholic liver disease, unspecified
0.645 0.355 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.643 0.357 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.642 0.358 0.000
S64 Injury of nerves at wrist and hand level
0.642 0.358 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.642 0.358 0.000
S40-S49 Injuries to the shoulder and upper arm
0.642 0.358 0.000
I35.0 Aortic (valve) stenosis
0.641 0.359 0.000
E83.4 Disorders of magnesium metabolism
0.641 0.359 0.000
R04 Haemorrhage from respiratory passages
0.640 0.359 0.000
Chapter I Certain infectious and parasitic diseases
0.640 0.360 0.000
T40.6 Other and unspecified narcotics
0.640 0.360 0.000
I61 Intracerebral haemorrhage
0.640 0.360 0.000
F60 Specific personality disorders
0.640 0.360 0.000
I65.2 Occlusion and stenosis of carotid artery
0.639 0.361 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.639 0.361 0.000
T45.0 Antiallergic and antiemetic drugs
0.638 0.362 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.637 0.363 0.000
M54.2 Cervicalgia
0.637 0.363 0.000
R07.1 Chest pain on breathing
0.636 0.364 0.000
I42 Cardiomyopathy
0.636 0.364 0.000
I05-I09 Chronic rheumatic heart diseases
0.635 0.365 0.000
R01 Cardiac murmurs and other cardiac sounds
0.633 0.366 0.000
T39.0 Salicylates
0.633 0.367 0.000
T17 Foreign body in respiratory tract
0.633 0.367 0.000
M65-M68 Disorders of synovium and tendon
0.633 0.367 0.000
E83.5 Disorders of calcium metabolism
0.632 0.367 0.000
S09 Other and unspecified injuries of head
0.632 0.368 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.631 0.369 0.000
E11 Non-insulin-dependent diabetes mellitus
0.631 0.369 0.000
S08 Traumatic amputation of part of head
0.630 0.370 0.000
S07 Crushing injury of head
0.630 0.370 0.000
S05 Injury of eye and orbit
0.630 0.370 0.000
S04 Injury of cranial nerves
0.630 0.370 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.630 0.370 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.629 0.370 0.000
S61.8 Open wound of other parts of wrist and hand
0.629 0.371 0.000
I31.3 Pericardial effusion (noninflammatory)
0.628 0.371 0.000
M54.8 Other dorsalgia
0.628 0.372 0.000
M54.0 Panniculitis affecting regions of neck and back
0.628 0.372 0.000
E34 Other endocrine disorders
0.628 0.372 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.628 0.372 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.627 0.373 0.000
S68 Traumatic amputation of wrist and hand
0.627 0.373 0.000
E87.6 Hypokalaemia
0.626 0.374 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.626 0.374 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.625 0.375 0.000
E83.8 Other disorders of mineral metabolism
0.625 0.375 0.000
E83.2 Disorders of zinc metabolism
0.625 0.375 0.000
E83.0 Disorders of copper metabolism
0.625 0.375 0.000
E27 Other disorders of adrenal gland
0.624 0.376 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.624 0.376 0.000
I24.1 Dressler's syndrome
0.624 0.376 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.624 0.376 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.623 0.377 0.000
I44 Atrioventricular and left bundle-branch block
0.622 0.378 0.000
K70.3 Alcoholic cirrhosis of liver
0.622 0.378 0.000
K50.1 Crohn's disease of large intestine
0.622 0.378 0.000
M47 Spondylosis
0.621 0.379 0.000
K51.8 Other ulcerative colitis
0.621 0.379 0.000
I22.8 Subsequent myocardial infarction of other sites
0.621 0.379 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.621 0.379 0.000
K65-K67 Diseases of peritoneum
0.620 0.379 0.000
S50-S59 Injuries to the elbow and forearm
0.620 0.380 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.620 0.380 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.619 0.381 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.619 0.381 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.619 0.381 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.619 0.381 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.619 0.381 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.619 0.381 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.619 0.381 0.000
F11 Mental and behavioural disorders due to use of opioids
0.619 0.381 0.000
I78 Diseases of capillaries
0.619 0.381 0.000
M54.4 Lumbago with sciatica
0.619 0.381 0.000
M54.1 Radiculopathy
0.618 0.382 0.000
M54.37 Sciatica (Lumbosacral region)
0.618 0.382 0.000
R29.4 Clicking hip
0.617 0.383 0.000
R29.3 Abnormal posture
0.617 0.383 0.000
R29.2 Abnormal reflex
0.617 0.383 0.000
R29.1 Meningismus
0.617 0.383 0.000
R29.0 Tetany
0.617 0.383 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.617 0.383 0.000
S20-S29 Injuries to the thorax
0.615 0.385 0.000
T42.4 Benzodiazepines
0.615 0.385 0.000
I10-I15 Hypertensive diseases
0.614 0.386 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.614 0.386 0.000
M94 Other disorders of cartilage
0.613 0.386 0.000
I67.8 Other specified cerebrovascular diseases
0.613 0.387 0.000
T86 Failure and rejection of transplanted organs and tissues
0.613 0.387 0.000
T65 Toxic effect of other and unspecified substances
0.613 0.387 0.000
T63 Toxic effect of contact with venomous animals
0.613 0.387 0.000
T62 Toxic effect of other noxious substances eaten as food
0.613 0.387 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.613 0.387 0.000
T60 Toxic effect of pesticides
0.613 0.387 0.000
T59 Toxic effect of other gases, fumes and vapours
0.613 0.387 0.000
T57 Toxic effect of other inorganic substances
0.613 0.387 0.000
T56 Toxic effect of metals
0.613 0.387 0.000
T54 Toxic effect of corrosive substances
0.613 0.387 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.613 0.387 0.000
T52 Toxic effect of organic solvents
0.613 0.387 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.613 0.387 0.000
T58 Toxic effect of carbon monoxide
0.613 0.387 0.000
T55 Toxic effect of soaps and detergents
0.613 0.387 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.613 0.387 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.613 0.387 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.613 0.387 0.000
T42.3 Barbiturates
0.613 0.387 0.000
T42.2 Succinimides and oxazolidinediones
0.613 0.387 0.000
T42.1 Iminostilbenes
0.613 0.387 0.000
T42.0 Hydantoin derivatives
0.613 0.387 0.000
K92 Other diseases of digestive system
0.612 0.388 0.000
H30-H36 Disorders of choroid and retina
0.612 0.388 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.611 0.389 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.611 0.389 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.611 0.389 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.611 0.389 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.611 0.389 0.000
I71.0 Dissection of aorta [any part]
0.611 0.389 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.611 0.389 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.611 0.389 0.000
R29.6 Tendency to fall, not elsewhere classified
0.611 0.389 0.000
R26 Abnormalities of gait and mobility
0.610 0.390 0.000
F10.9 Unspecified mental and behavioural disorder
0.609 0.391 0.000
F10.8 Other mental and behavioural disorders
0.609 0.391 0.000
F10.7 Residual and late-onset psychotic disorder
0.609 0.391 0.000
F10.6 Amnesic syndrome
0.609 0.391 0.000
F10.5 Psychotic disorder
0.609 0.391 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.608 0.392 0.000
Y59 Other and unspecified vaccines and biological substances
0.608 0.392 0.000
Y58 Bacterial vaccines
0.608 0.392 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.608 0.392 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.608 0.392 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.608 0.392 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.608 0.392 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.608 0.392 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.608 0.392 0.000
Y48 Anaesthetics and therapeutic gases
0.608 0.392 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.608 0.392 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.608 0.392 0.000
Y44 Agents primarily affecting blood constituents
0.608 0.392 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.608 0.392 0.000
E11.9 Without complications
0.608 0.392 0.000
S01.3 Open wound of ear
0.608 0.392 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.608 0.392 0.000
I31.8 Other specified diseases of pericardium
0.607 0.393 0.000
I31.2 Haemopericardium, not elsewhere classified
0.607 0.393 0.000
I31.1 Chronic constrictive pericarditis
0.607 0.393 0.000
I31.0 Chronic adhesive pericarditis
0.607 0.393 0.000
Y40 Systemic antibiotics
0.607 0.393 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.606 0.394 0.000
E28 Ovarian dysfunction
0.606 0.394 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.606 0.394 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.606 0.394 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.605 0.394 0.000
E22 Hyperfunction of pituitary gland
0.605 0.395 0.000
I46.0 Cardiac arrest with successful resuscitation
0.605 0.395 0.000
H10-H13 Disorders of conjunctiva
0.605 0.395 0.000
V10-V19 Pedal cyclist injured in transport accident
0.604 0.395 0.000
S06.5 Traumatic subdural haemorrhage
0.604 0.395 0.000
K50.0 Crohn's disease of small intestine
0.604 0.396 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.604 0.396 0.000
R27.0 Ataxia, unspecified
0.603 0.397 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.603 0.397 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.602 0.398 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.602 0.398 0.000
T39.4 Antirheumatics, not elsewhere classified
0.602 0.398 0.000
T39.2 Pyrazolone derivatives
0.602 0.398 0.000
M50 Cervical disk disorders
0.602 0.398 0.000
K51.2 Ulcerative (chronic) proctitis
0.600 0.400 0.000
I35.1 Aortic (valve) insufficiency
0.600 0.400 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.600 0.400 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.600 0.400 0.000
S72 Fracture of femur
0.599 0.401 0.000
K50.8 Other Crohn's disease
0.598 0.402 0.000
S61.7 Multiple open wounds of wrist and hand
0.598 0.402 0.000
R94.4 Abnormal results of kidney function studies
0.598 0.402 0.000
I47.1 Supraventricular tachycardia
0.597 0.403 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.596 0.404 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.595 0.405 0.000
I77.1 Stricture of artery
0.595 0.405 0.000
H81 Disorders of vestibular function
0.595 0.405 0.000
E46 Unspecified protein-energy malnutrition
0.594 0.405 0.000
Z93 Artificial opening status
0.594 0.406 0.000
M70-M79 Other soft tissue disorders
0.594 0.406 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.594 0.406 0.000
H54.7 Unspecified visual loss
0.593 0.407 0.000
S61.1 Open wound of finger(s) with damage to nail
0.592 0.407 0.000
M05-M14 Inflammatory polyarthropathies
0.592 0.408 0.000
M45 Ankylosing spondylitis
0.592 0.408 0.000
S12 Fracture of neck
0.591 0.409 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.590 0.410 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.589 0.411 0.000
I72.3 Aneurysm of iliac artery
0.589 0.411 0.000
I50 Heart failure
0.589 0.411 0.000
I67.2 Cerebral atherosclerosis
0.589 0.411 0.000
E89.0 Postprocedural hypothyroidism
0.588 0.412 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.588 0.412 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.587 0.413 0.000
H43-H45 Disorders of vitreous body and globe
0.586 0.414 0.000
S92 Fracture of foot, except ankle
0.586 0.414 0.000
R40 Somnolence, stupor and coma
0.583 0.417 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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