TreeWAS – Variant ID: rs80058714

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
I30-I52 Other forms of heart disease	0.994	0.006
Chapter XII Diseases of the skin and subcutaneous tissue	0.992	0.008
M50-M54 Other dorsopathies	0.992	0.008
E10-E14 Diabetes mellitus	0.990	0.010
M54 Dorsalgia	0.988	0.012
I25.1 Atherosclerotic heart disease	0.984	0.016
L60-L75 Disorders of skin appendages	0.983	0.017
I25.8 Other forms of chronic ischaemic heart disease	0.982	0.018
I25.9 Chronic ischaemic heart disease, unspecified	0.981	0.019
M20-M25 Other joint disorders	0.979	0.021
M54.5 Low back pain	0.978	0.022
L72 Follicular cysts of skin and subcutaneous tissue	0.976	0.024
I47 Paroxysmal tachycardia	0.974	0.026
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.968	0.032
E10 Insulin-dependent diabetes mellitus	0.964	0.036
M54.59 Low back pain (Site unspecified)	0.958	0.042
D60-D64 Aplastic and other anaemias	0.953	0.047
S90-S99 Injuries to the ankle and foot	0.951	0.049
M45-M49 Spondylopathies	0.949	0.051
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.946	0.054
I47.1 Supraventricular tachycardia	0.943	0.057
M35 Other systemic involvement of connective tissue	0.938	0.062
L20-L30 Dermatitis and eczema	0.938	0.062
Chapter VI Diseases of the nervous system	0.932	0.068
T36-T50 Poisoning by drugs, medicaments and biological substances	0.929	0.071
I50 Heart failure	0.928	0.072
M48 Other spondylopathies	0.926	0.074
L72.0 Epidermal cyst	0.923	0.077
Chapter V Mental and behavioural disorders	0.922	0.078
M70-M79 Other soft tissue disorders	0.919	0.081
M54.9 Dorsalgia, unspecified	0.914	0.086
M35.3 Polymyalgia rheumatica	0.914	0.086
M25 Other joint disorders, not elsewhere classified	0.908	0.092
D63 Anaemia in chronic diseases classified elsewhere	0.906	0.094
M48.0 Spinal stenosis	0.900	0.100
I35 Nonrheumatic aortic valve disorders	0.898	0.102
M79 Other soft tissue disorders, not elsewhere classified	0.898	0.102
I24 Other acute ischaemic heart diseases	0.896	0.104
I70-I79 Diseases of arteries, arterioles and capillaries	0.895	0.105
E20-E35 Disorders of other endocrine glands	0.894	0.106
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.891	0.109
E14 Unspecified diabetes mellitus	0.889	0.111
M86-M90 Other osteopathies	0.887	0.113
M80-M85 Disorders of bone density and structure	0.883	0.117
D64 Other anaemias	0.877	0.123
Q60-Q64 Congenital malformations of the urinary system	0.877	0.123
I21 Acute myocardial infarction	0.864	0.136
E11 Non-insulin-dependent diabetes mellitus	0.864	0.136
I50.0 Congestive heart failure	0.856	0.144
L72.1 Trichilemmal cyst	0.855	0.145
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.853	0.147
M54.56 Low back pain (Lumbar region)	0.852	0.148
I20 Angina pectoris	0.850	0.150
D63.0 Anaemia in neoplastic disease	0.849	0.151
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.848	0.152
I47.2 Ventricular tachycardia	0.847	0.153
S92 Fracture of foot, except ankle	0.846	0.154
E10.3 With ophthalmic complications	0.845	0.155
I45 Other conduction disorders	0.845	0.155
G35-G37 Demyelinating diseases of the central nervous system	0.843	0.157
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.843	0.157
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.837	0.163
M48.06 Spinal stenosis (Lumbar region)	0.834	0.166
Chapter VIII Diseases of the ear and mastoid process	0.833	0.167
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.832	0.168
E10.9 Without complications	0.831	0.169
Chapter VII Diseases of the eye and adnexa	0.829	0.171
L00-L08 Infections of the skin and subcutaneous tissue	0.828	0.172
M54.99 Dorsalgia, unspecified (Site unspecified)	0.825	0.175
D64.9 Anaemia, unspecified	0.823	0.177
E14.9 Without complications	0.823	0.177
F20 Schizophrenia	0.822	0.178
Q61 Cystic kidney disease	0.819	0.181
I35.0 Aortic (valve) stenosis	0.818	0.182
M79.0 Rheumatism, unspecified	0.816	0.184
I24.9 Acute ischaemic heart disease, unspecified	0.816	0.184
M48.09 Spinal stenosis (Site unspecified)	0.812	0.188
I73 Other peripheral vascular diseases	0.812	0.188
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.810	0.190
I35.2 Aortic (valve) stenosis with insufficiency	0.808	0.192
I25.3 Aneurysm of heart	0.807	0.192
E10.5 With peripheral circulatory complications	0.805	0.195
Chapter XX External causes of morbidity and mortality	0.804	0.196
S10-S19 Injuries to the neck	0.800	0.200
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.799	0.201
D70-D77 Other diseases of blood and blood-forming organs	0.798	0.201
M30 Polyarteritis nodosa and related conditions	0.798	0.202
M24 Other specific joint derangements	0.797	0.203
M79.7 Fibromyalgia	0.797	0.203
S60-S69 Injuries to the wrist and hand	0.796	0.204
M25.8 Other specified joint disorders	0.796	0.204
M34 Systemic sclerosis	0.794	0.206
L27 Dermatitis due to substances taken internally	0.792	0.208
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.791	0.209
I50.1 Left ventricular failure	0.789	0.211
I20.9 Angina pectoris, unspecified	0.789	0.211
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.787	0.213
L30 Other dermatitis	0.787	0.213
E11.9 Without complications	0.786	0.214
M90 Osteopathies in diseases classified elsewhere	0.785	0.214
E10.4 With neurological complications	0.785	0.214
M60-M63 Disorders of muscles	0.785	0.215
I51 Complications and ill-defined descriptions of heart disease	0.785	0.215
I44 Atrioventricular and left bundle-branch block	0.782	0.218
M54.4 Lumbago with sciatica	0.779	0.221
G35 Multiple sclerosis	0.778	0.222
I21.4 Acute subendocardial myocardial infarction	0.778	0.222
D62 Acute posthaemorrhagic anaemia	0.778	0.222
T42.4 Benzodiazepines	0.775	0.225
G30-G32 Other degenerative diseases of the nervous system	0.775	0.225
M91-M94 Chondropathies	0.772	0.227
M22 Disorders of patella	0.771	0.229
S80-S89 Injuries to the knee and lower leg	0.771	0.229
F80-F89 Disorders of psychological development	0.769	0.231
I05-I09 Chronic rheumatic heart diseases	0.768	0.232
I77 Other disorders of arteries and arterioles	0.768	0.232
M33 Dermatopolymyositis	0.767	0.233
I25.5 Ischaemic cardiomyopathy	0.766	0.234
M84 Disorders of continuity of bone	0.766	0.234
T66-T78 Other and unspecified effects of external causes	0.766	0.234
H90-H95 Other disorders of ear	0.766	0.234
M79.8 Other specified soft tissue disorders	0.765	0.235
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.765	0.235
L29 Pruritus	0.763	0.237
S96 Injury of muscle and tendon at ankle and foot level	0.763	0.237
M54.96 Dorsalgia, unspecified (Lumbar region)	0.762	0.238
E13 Other specified diabetes mellitus	0.762	0.238
F29 Unspecified nonorganic psychosis	0.761	0.239
I10-I15 Hypertensive diseases	0.760	0.240
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.759	0.241
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.759	0.241
I34 Nonrheumatic mitral valve disorders	0.758	0.242
E50-E64 Other nutritional deficiencies	0.758	0.242
M48.5 Collapsed vertebra, not elsewhere classified	0.758	0.242
D63.8 Anaemia in other chronic diseases classified elsewhere	0.757	0.243
I73.9 Peripheral vascular disease, unspecified	0.756	0.244
M25.3 Other instability of joint	0.754	0.246
L65 Other nonscarring hair loss	0.753	0.247
M25.5 Pain in joint	0.752	0.248
M25.6 Stiffness of joint, not elsewhere classified	0.751	0.249
E10.2 With renal complications	0.750	0.250
G80-G83 Cerebral palsy and other paralytic syndromes	0.749	0.251
I25.2 Old myocardial infarction	0.747	0.253
S62 Fracture at wrist and hand level	0.746	0.254
L28 Lichen simplex chronicus and prurigo	0.746	0.254
S99 Other and unspecified injuries of ankle and foot	0.745	0.254
L71 Rosacea	0.744	0.255
E28 Ovarian dysfunction	0.744	0.256
H55-H59 Other disorders of eye and adnexa	0.744	0.256
H53-H54 Visual disturbances and blindness	0.743	0.257
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.742	0.258
M49 Spondylopathies in diseases classified elsewhere	0.742	0.258
F20.9 Schizophrenia, unspecified	0.742	0.258
I21.0 Acute transmural myocardial infarction of anterior wall	0.741	0.259
S20-S29 Injuries to the thorax	0.739	0.261
G63 Polyneuropathy in diseases classified elsewhere	0.739	0.261
T88 Other complications of surgical and medical care, not elsewhere classified	0.737	0.263
E70-E90 Metabolic disorders	0.733	0.267
S91 Open wound of ankle and foot	0.730	0.270
Q80-Q89 Other congenital malformations	0.730	0.270
S70-S79 Injuries to the hip and thigh	0.729	0.271
I33 Acute and subacute endocarditis	0.729	0.271
S92.3 Fracture of metatarsal bone	0.725	0.275
I22 Subsequent myocardial infarction	0.725	0.275
M79.79 Fibromyalgia (Site unspecified)	0.725	0.275
M79.09 Rheumatism, unspecified (Site unspecified)	0.720	0.280
I70 Atherosclerosis	0.718	0.282
L08 Other local infections of skin and subcutaneous tissue	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
G90-G99 Other disorders of the nervous system	0.717	0.283
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.716	0.283
G62 Other polyneuropathies	0.715	0.285
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
M25.55 Pain in joint (Pelvic region and thigh)	0.714	0.286
E40-E46 Malnutrition	0.713	0.287
Q50-Q56 Congenital malformations of genital organs	0.713	0.287
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I37 Pulmonary valve disorders	0.713	0.287
I36 Nonrheumatic tricuspid valve disorders	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
M90.7 Fracture of bone in neoplastic disease	0.713	0.287
M54.57 Low back pain (Lumbosacral region)	0.712	0.288
L10-L14 Bullous disorders	0.711	0.288
M53 Other dorsopathies, not elsewhere classified	0.711	0.289
M82 Osteoporosis in diseases classified elsewhere	0.711	0.289
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.710	0.290
E12 Malnutrition-related diabetes mellitus	0.710	0.290
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.710	0.290
M54.8 Other dorsalgia	0.708	0.292
M54.6 Pain in thoracic spine	0.708	0.292
M54.0 Panniculitis affecting regions of neck and back	0.708	0.292
T82.1 Mechanical complication of cardiac electronic device	0.708	0.292
Q61.2 Polycystic kidney, adult type	0.707	0.293
H46-H48 Disorders of optic nerve and visual pathways	0.707	0.293
L75 Apocrine sweat disorders	0.705	0.295
L74 Eccrine sweat disorders	0.705	0.295
L70 Acne	0.705	0.295
L68 Hypertrichosis	0.705	0.295
L67 Hair colour and hair shaft abnormalities	0.705	0.295
L66 Cicatricial alopecia [scarring hair loss]	0.705	0.295
L64 Androgenic alopecia	0.705	0.295
L63 Alopecia areata	0.705	0.295
L62 Nail disorders in diseases classified elsewhere	0.705	0.295
M25.0 Haemarthrosis	0.704	0.296
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.703	0.297
L73 Other follicular disorders	0.703	0.297
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.702	0.298
M32 Systemic lupus erythematosus	0.702	0.298
M54.55 Low back pain (Thoracolumbar region)	0.701	0.299
M54.54 Low back pain-Thoracic	0.701	0.299
M54.53 Low back pain-Cervicothoracic	0.701	0.299
M54.52 Low back pain-Cervical	0.701	0.299
M54.51 Low back pain-Occipit-atl-axl	0.701	0.299
M54.50 Low back pain (Multiple sites in spine)	0.701	0.299
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.701	0.299
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.700	0.299
I24.8 Other forms of acute ischaemic heart disease	0.700	0.299
I45.1 Other and unspecified right bundle-branch block	0.700	0.300
M77 Other enthesopathies	0.700	0.300
M54.3 Sciatica	0.700	0.300
E11.0 With coma	0.700	0.300
L72.2 Steatocystoma multiplex	0.700	0.300
I47.9 Paroxysmal tachycardia, unspecified	0.699	0.301
I47.0 Reentry ventricular arrhythmia	0.699	0.301
V80-V89 Other land transport accidents	0.698	0.302
I30 Acute pericarditis	0.697	0.302
E11.4 With neurological complications	0.697	0.302
E24 Cushing's syndrome	0.697	0.303
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.697	0.303
G30 Alzheimer's disease	0.696	0.304
M25.84 Other specified joint disorders (Hand)	0.696	0.304
D55-D59 Haemolytic anaemias	0.694	0.306
T79-T79 Certain early complications of trauma	0.693	0.307
E20 Hypoparathyroidism	0.692	0.308
L40-L45 Papulosquamous disorders	0.691	0.309
E10.8 With unspecified complications	0.691	0.309
E10.7 With multiple complications	0.691	0.309
E10.6 With other specified complications	0.691	0.309
E10.0 With coma	0.691	0.309
M79.1 Myalgia	0.689	0.311
F25 Schizoaffective disorders	0.689	0.311
I44.1 Atrioventricular block, second degree	0.688	0.312
H92 Otalgia and effusion of ear	0.688	0.312
H53 Visual disturbances	0.687	0.313
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.687	0.313
M84.1 Nonunion of fracture [pseudarthrosis]	0.686	0.314
E23 Hypofunction and other disorders of pituitary gland	0.686	0.314
L29.0 Pruritus ani	0.686	0.314
F22 Persistent delusional disorders	0.686	0.314
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.685	0.315
E65-E68 Obesity and other hyperalimentation	0.685	0.315
H53.2 Diplopia	0.684	0.316
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.683	0.317
F60-F69 Disorders of adult personality and behaviour	0.682	0.318
D68 Other coagulation defects	0.682	0.318
S98 Traumatic amputation of ankle and foot	0.682	0.318
S97 Crushing injury of ankle and foot	0.682	0.318
S95 Injury of blood vessels at ankle and foot level	0.682	0.318
S94 Injury of nerves at ankle and foot level	0.682	0.318
S90 Superficial injury of ankle and foot	0.682	0.318
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.682	0.318
I44.0 Atrioventricular block, first degree	0.682	0.318
M85 Other disorders of bone density and structure	0.680	0.320
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.679	0.321
F20.0 Paranoid schizophrenia	0.679	0.321
Q61.3 Polycystic kidney, unspecified	0.678	0.322
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.678	0.322
Q35-Q37 Cleft lip and cleft palate	0.678	0.322
Q30-Q34 Congenital malformations of the respiratory system	0.678	0.322
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.678	0.322
E87 Other disorders of fluid, electrolyte and acid-base balance	0.678	0.322
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.677	0.323
Q61.0 Congenital single renal cyst	0.677	0.323
E22 Hyperfunction of pituitary gland	0.676	0.323
M48.02 Spinal stenosis (Cervical region)	0.675	0.325
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.674	0.326
M79.00 Rheumatism, unspecified (Multiple sites)	0.674	0.326
D73 Diseases of spleen	0.674	0.326
M35.9 Systemic involvement of connective tissue, unspecified	0.673	0.327
M35.8 Other specified systemic involvement of connective tissue	0.673	0.327
M35.7 Hypermobility syndrome	0.673	0.327
M35.6 Relapsing panniculitis [Weber-Christian]	0.673	0.327
M35.5 Multifocal fibrosclerosis	0.673	0.327
M35.4 Diffuse (eosinophilic) fasciitis	0.673	0.327
M35.2 Behcet's disease	0.673	0.327
M35.1 Other overlap syndromes	0.673	0.327
I49 Other cardiac arrhythmias	0.673	0.327
M86 Osteomyelitis	0.672	0.327
Q38-Q45 Other congenital malformations of the digestive system	0.672	0.327
L27.1 Localised skin eruption due to drugs and medicaments	0.672	0.327
L25 Unspecified contact dermatitis	0.672	0.328
L24 Irritant contact dermatitis	0.672	0.328
L23 Allergic contact dermatitis	0.672	0.328
L21 Seborrhoeic dermatitis	0.672	0.328
L20 Atopic dermatitis	0.672	0.328
L26 Exfoliative dermatitis	0.672	0.328
L22 Diaper [napkin] dermatitis	0.672	0.328
T93 Sequelae of injuries of lower limb	0.672	0.328
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.671	0.329
D72 Other disorders of white blood cells	0.670	0.330
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.669	0.330
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.669	0.331
M50 Cervical disk disorders	0.669	0.331
Q20-Q28 Congenital malformations of the circulatory system	0.668	0.331
S92.4 Fracture of great toe	0.668	0.332
Q63 Other congenital malformations of kidney	0.667	0.333
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.666	0.334
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.666	0.334
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.666	0.334
T46 Poisoning by agents primarily affecting the cardiovascular system	0.666	0.334
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.666	0.334
T41 Poisoning by anaesthetics and therapeutic gases	0.666	0.334
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.666	0.334
T36 Poisoning by systemic antibiotics	0.666	0.334
I21.1 Acute transmural myocardial infarction of inferior wall	0.666	0.334
L50-L54 Urticaria and erythema	0.666	0.334
L30.8 Other specified dermatitis	0.664	0.336
S62.3 Fracture of other metacarpal bone	0.664	0.336
M48.9 Spondylopathy, unspecified	0.664	0.336
M48.8 Other specified spondylopathies	0.664	0.336
M48.4 Fatigue fracture of vertebra	0.664	0.336
M48.3 Traumatic spondylopathy	0.664	0.336
M48.2 Kissing spine	0.664	0.336
M48.1 Ankylosing hyperostosis [Forestier]	0.664	0.336
M70 Soft tissue disorders related to use, overuse and pressure	0.664	0.336
H10-H13 Disorders of conjunctiva	0.663	0.337
I51.7 Cardiomegaly	0.663	0.337
L05 Pilonidal cyst	0.662	0.338
M40-M43 Deforming dorsopathies	0.662	0.338
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.661	0.339
F70-F79 Mental retardation	0.661	0.339
E10.1 With ketoacidosis	0.661	0.339
M48.00 Spinal stenosis (Multiple sites in spine)	0.661	0.339
F81 Specific developmental disorders of scholastic skills	0.659	0.341
S50-S59 Injuries to the elbow and forearm	0.659	0.341
M76 Enthesopathies of lower limb, excluding foot	0.659	0.341
M73 Soft tissue disorders in diseases classified elsewhere	0.659	0.341
M54.1 Radiculopathy	0.657	0.343
G63.2 Diabetic polyneuropathy	0.657	0.343
M79.5 Residual foreign body in soft tissue	0.656	0.344
M89 Other disorders of bone	0.656	0.344
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.655	0.344
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.655	0.344
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.655	0.344
M54.94 Dorsalgia, unspecified (Thoracic region)	0.655	0.344
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.655	0.344
M54.92 Dorsalgia, unspecified (Cervical region)	0.655	0.344
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.655	0.344
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.655	0.344
Q00-Q07 Congenital malformations of the nervous system	0.655	0.345
M71 Other bursopathies	0.655	0.345
M21 Other acquired deformities of limbs	0.655	0.345
Chapter XXII Codes for special purposes	0.654	0.346
M48.07 Spinal stenosis (Lumbosacral region)	0.654	0.346
T15-T19 Effects of foreign body entering through natural orifice	0.651	0.349
M25.9 Joint disorder, unspecified	0.651	0.349
M25.2 Flail joint	0.651	0.349
M25.1 Fistula of joint	0.651	0.349
M24.2 Disorder of ligament	0.651	0.349
I44.3 Other and unspecified atrioventricular block	0.650	0.350
D63.1 Anaemia in other chronic diseases classified elsewhere	0.650	0.350
M79.86 Other specified soft tissue disorders (Lower leg)	0.648	0.352
M87 Osteonecrosis	0.647	0.353
S92.0 Fracture of calcaneus	0.647	0.353
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.645	0.354
M48.05 Spinal stenosis (Thoracolumbar region)	0.645	0.354
M48.04 Spinal stenosis (Thoracic region)	0.645	0.354
M48.03 Spinal stenosis (Cervicothoracic region)	0.645	0.354
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.645	0.354
G00-G09 Inflammatory diseases of the central nervous system	0.645	0.355
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.645	0.355
H57 Other disorders of eye and adnexa	0.644	0.356
M54.2 Cervicalgia	0.644	0.356
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.644	0.356
M25.34 Other instability of joint (Hand)	0.644	0.356
M79.9 Soft tissue disorder, unspecified	0.644	0.356
M79.4 Hypertrophy of (infrapatellar) fat pad	0.644	0.356
M79.3 Panniculitis, unspecified	0.644	0.356
M79.2 Neuralgia and neuritis, unspecified	0.644	0.356
T31 Burns classified according to extent of body surface involved	0.644	0.356
L60 Nail disorders	0.643	0.357
M24.8 Other specific joint derangements, not elsewhere classified	0.643	0.357
I24.1 Dressler's syndrome	0.643	0.357
I45.3 Trifascicular block	0.642	0.358
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.642	0.358
E27 Other disorders of adrenal gland	0.642	0.358
F30-F39 Mood [affective] disorders	0.642	0.358
E35 Disorders of endocrine glands in diseases classified elsewhere	0.641	0.359
E34 Other endocrine disorders	0.641	0.359
E32 Diseases of thymus	0.641	0.359
E31 Polyglandular dysfunction	0.641	0.359
E30 Disorders of puberty, not elsewhere classified	0.641	0.359
E26 Hyperaldosteronism	0.641	0.359
E25 Adrenogenital disorders	0.641	0.359
G61 Inflammatory polyneuropathy	0.641	0.359
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.640	0.360
G30.9 Alzheimer's disease, unspecified	0.640	0.360
S40-S49 Injuries to the shoulder and upper arm	0.639	0.361
S92.30 Fracture of metatarsal bone (closed)	0.639	0.361
F23 Acute and transient psychotic disorders	0.638	0.361
F28 Other nonorganic psychotic disorders	0.638	0.361
F24 Induced delusional disorder	0.638	0.361
F21 Schizotypal disorder	0.638	0.361
E14.8 With unspecified complications	0.637	0.363
E14.7 With multiple complications	0.637	0.363
E14.6 With other specified complications	0.637	0.363
E14.5 With peripheral circulatory complications	0.637	0.363
E14.4 With neurological complications	0.637	0.363
E14.2 Withrenal complications	0.637	0.363
E14.1 With ketoacidosis	0.637	0.363
E14.0 With coma	0.637	0.363
T86 Failure and rejection of transplanted organs and tissues	0.637	0.363
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.637	0.363
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.636	0.364
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.636	0.364
E28.2 Polycystic ovarian syndrome	0.636	0.364
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.636	0.364
M05-M14 Inflammatory polyarthropathies	0.635	0.365
I95-I99 Other and unspecified disorders of the circulatory system	0.635	0.365
S80 Superficial injury of lower leg	0.634	0.366
S12 Fracture of neck	0.634	0.366
M34.1 CR(E)ST syndrome	0.634	0.366
M54.49 Lumbago with sciatica (Site unspecified)	0.633	0.367
M83 Adult osteomalacia	0.633	0.367
M51 Other intervertebral disk disorders	0.632	0.368
I72 Other aneurysm	0.631	0.369
H91 Other hearing loss	0.631	0.369
M62 Other disorders of muscle	0.631	0.369
D64.8 Other specified anaemias	0.629	0.371
D64.4 Congenital dyserythropoietic anaemia	0.629	0.371
D64.3 Other sideroblastic anaemias	0.629	0.371
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.629	0.371
D64.1 Secondary sideroblastic anaemia due to disease	0.629	0.371
D64.0 Hereditary sideroblastic anaemia	0.629	0.371
Q64 Other congenital malformations of urinary system	0.629	0.371
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.629	0.371
Q60 Renal agenesis and other reduction defects of kidney	0.629	0.371
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.628	0.372
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.627	0.373
E11.1 With ketoacidosis	0.627	0.373
H65-H75 Diseases of middle ear and mastoid	0.627	0.373
S62.6 Fracture of other finger	0.626	0.373
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.626	0.374
Q76 Congenital malformations of spine and bony thorax	0.625	0.374
M35.0 Sicca syndrome [Sjogren]	0.624	0.376
M88 Paget's disease of bone [osteitis deformans]	0.624	0.376
M65-M68 Disorders of synovium and tendon	0.624	0.376
E87.6 Hypokalaemia	0.624	0.376
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.624	0.376
X58-X59 Accidental exposure to other and unspecified factors	0.623	0.377
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.622	0.377
I45.5 Other specified heart block	0.622	0.378
S93.1 Dislocation of toe(s)	0.622	0.378
F99-F99 Unspecified mental disorder	0.621	0.379
M81 Osteoporosis without pathological fracture	0.621	0.379
M45 Ankylosing spondylitis	0.621	0.379
I08 Multiple valve diseases	0.621	0.379
I21.X Presumed acute myicardial infaction (unconfirmed)	0.620	0.380
I21.3 Acute transmural myocardial infarction of unspecified site	0.620	0.380
E11.8 With unspecified complications	0.619	0.381
E11.7 With multiple complications	0.619	0.381
E11.6 With other specified complications	0.619	0.381
H30-H36 Disorders of choroid and retina	0.619	0.381
D75 Other diseases of blood and blood-forming organs	0.618	0.382
I77.6 Arteritis, unspecified	0.618	0.382
M25.58 Pain in joint (Other)	0.617	0.383
G62.9 Polyneuropathy, unspecified	0.617	0.383
I51.4 Myocarditis, unspecified	0.616	0.384
M33.1 Other dermatomyositis	0.616	0.384
M46 Other inflammatory spondylopathies	0.615	0.385
I45.9 Conduction disorder, unspecified	0.614	0.386
M92 Other juvenile osteochondrosis	0.614	0.386
M79.84 Other specified soft tissue disorders (Hand)	0.614	0.386
I45.6 Preexcitation syndrome	0.614	0.386
T87 Complications peculiar to reattachment and amputation	0.613	0.387
V40-V49 Car occupant injured in transport accident	0.612	0.388
M79.6 Pain in limb	0.612	0.388
I34.1 Mitral (valve) prolapse	0.612	0.388
I12 Hypertensive renal disease	0.612	0.388

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations