TreeWAS – Variant ID: rs16902048

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
C61 Malignant neoplasm of prostate	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
C60-C63 Malignant neoplasms of male genital organs	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	0.999	0.001
M45-M49 Spondylopathies	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
M47 Spondylosis	0.990	0.010
Chapter VIII Diseases of the ear and mastoid process	0.986	0.014
M47.8 Other spondylosis	0.983	0.017
R50-R69 General symptoms and signs	0.981	0.019
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.981	0.019
S40-S49 Injuries to the shoulder and upper arm	0.970	0.030
Chapter XIV Diseases of the genitourinary system	0.969	0.031
R04 Haemorrhage from respiratory passages	0.966	0.034
H65-H75 Diseases of middle ear and mastoid	0.963	0.037
R04.0 Epistaxis	0.962	0.038
M20-M25 Other joint disorders	0.961	0.039
N20-N23 Urolithiasis	0.961	0.039
M50-M54 Other dorsopathies	0.957	0.043
N20 Calculus of kidney and ureter	0.950	0.050
Chapter IV Endocrine, nutritional and metabolic diseases	0.948	0.052
S42 Fracture of shoulder and upper arm	0.940	0.060
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.937	0.063
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.934	0.066
M47.82 Other spondylosis (Cervical region)	0.930	0.070
M50 Cervical disk disorders	0.927	0.073
C15-C26 Malignant neoplasms of digestive organs	0.926	0.074
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.923	0.077
N20.1 Calculus of ureter	0.923	0.077
S42.2 Fracture of upper end of humerus	0.913	0.087
N17-N19 Renal failure	0.910	0.090
M48 Other spondylopathies	0.909	0.091
R59 Enlarged lymph nodes	0.908	0.092
M50.1 Cervical disk disorder with radiculopathy	0.903	0.097
R53 Malaise and fatigue	0.899	0.101
S42.20 Fracture of upper end of humerus (closed)	0.895	0.105
Chapter X Diseases of the respiratory system	0.889	0.111
R60 Oedema, not elsewhere classified	0.885	0.115
N18 Chronic renal failure	0.884	0.116
H60-H62 Diseases of external ear	0.884	0.116
Chapter IX Diseases of the circulatory system	0.879	0.121
M47.80 Other spondylosis (Multiple sites in spine)	0.876	0.124
H66 Suppurative and unspecified otitis media	0.874	0.126
M47.87 Other spondylosis (Lumbosacral region)	0.869	0.131
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.867	0.133
E20-E35 Disorders of other endocrine glands	0.865	0.135
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.861	0.139
M23 Internal derangement of knee	0.860	0.140
R44 Other symptoms and signs involving general sensations and perceptions	0.859	0.141
M86-M90 Other osteopathies	0.852	0.148
Chapter XX External causes of morbidity and mortality	0.851	0.149
E70-E90 Metabolic disorders	0.851	0.149
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.847	0.153
M48.0 Spinal stenosis	0.847	0.153
H72 Perforation of tympanic membrane	0.847	0.153
N18.3 Chronic kidney disease, stage 3	0.845	0.155
C15 Malignant neoplasm of oesophagus	0.839	0.161
S20-S29 Injuries to the thorax	0.835	0.165
T93 Sequelae of injuries of lower limb	0.834	0.166
M24 Other specific joint derangements	0.833	0.167
R42 Dizziness and giddiness	0.831	0.169
E10-E14 Diabetes mellitus	0.829	0.171
N00-N08 Glomerular diseases	0.827	0.173
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.826	0.174
R51 Headache	0.824	0.176
I70-I79 Diseases of arteries, arterioles and capillaries	0.822	0.178
D37-D48 Neoplasms of uncertain or unknown behaviour	0.821	0.179
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.818	0.182
N20.0 Calculus of kidney	0.815	0.185
R63 Symptoms and signs concerning food and fluid intake	0.813	0.187
Chapter VI Diseases of the nervous system	0.811	0.189
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.811	0.189
H61 Other disorders of external ear	0.810	0.190
R56 Convulsions, not elsewhere classified	0.810	0.190
E83 Disorders of mineral metabolism	0.807	0.193
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.806	0.194
R59.0 Localised enlarged lymph nodes	0.806	0.194
R94 Abnormal results of function studies	0.806	0.194
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.806	0.194
M21 Other acquired deformities of limbs	0.805	0.195
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.804	0.196
J80-J84 Other respiratory diseases principally affecting the interstitium	0.804	0.196
M22 Disorders of patella	0.798	0.202
R58 Haemorrhage, not elsewhere classified	0.797	0.202
N20.2 Calculus of kidney with calculus of ureter	0.797	0.203
S10-S19 Injuries to the neck	0.795	0.205
C79 Secondary malignant neoplasm of other sites	0.794	0.206
M47.9 Spondylosis, unspecified	0.794	0.206
I60-I69 Cerebrovascular diseases	0.794	0.206
R45 Symptoms and signs involving emotional state	0.791	0.209
T92 Sequelae of injuries of upper limb	0.789	0.211
E27 Other disorders of adrenal gland	0.787	0.213
H65 Nonsuppurative otitis media	0.785	0.215
N23 Unspecified renal colic	0.784	0.216
R02 Gangrene, not elsewhere classified	0.783	0.217
C18 Malignant neoplasm of colon	0.782	0.218
M47.89 Other spondylosis (Site unspecified)	0.782	0.218
S46 Injury of muscle and tendon at shoulder and upper arm level	0.779	0.221
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.777	0.223
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.776	0.224
R93 Abnormal findings on diagnostic imaging of other body structures	0.775	0.225
H66.9 Otitis media, unspecified	0.773	0.227
S00-S09 Injuries to the head	0.773	0.227
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.773	0.227
Chapter XXII Codes for special purposes	0.773	0.227
M48.06 Spinal stenosis (Lumbar region)	0.770	0.230
R07 Pain in throat and chest	0.767	0.233
M47.86 Other spondylosis (Lumbar region)	0.765	0.235
R60.9 Oedema, unspecified	0.763	0.237
M47.1 Other spondylosis with myelopathy	0.763	0.237
I61 Intracerebral haemorrhage	0.762	0.238
H72.9 Perforation of tympanic membrane, unspecified	0.762	0.238
R44.1 Visual hallucinations	0.761	0.239
T90 Sequelae of injuries of head	0.759	0.241
R59.9 Enlarged lymph nodes, unspecified	0.757	0.243
M23.8 Other internal derangements of knee	0.757	0.243
R54 Senility	0.756	0.244
T66-T78 Other and unspecified effects of external causes	0.756	0.244
S42.0 Fracture of clavicle	0.751	0.249
C15.9 Oesophagus, unspecified	0.750	0.250
N21 Calculus of lower urinary tract	0.745	0.255
E11 Non-insulin-dependent diabetes mellitus	0.745	0.255
M31 Other necrotising vasculopathies	0.744	0.256
R60.0 Localised oedema	0.744	0.256
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.743	0.257
G90-G99 Other disorders of the nervous system	0.742	0.258
C16 Malignant neoplasm of stomach	0.739	0.261
M40-M43 Deforming dorsopathies	0.738	0.261
J20-J22 Other acute lower respiratory infections	0.738	0.262
M87 Osteonecrosis	0.737	0.263
M05-M14 Inflammatory polyarthropathies	0.737	0.263
E29 Testicular dysfunction	0.736	0.264
S70-S79 Injuries to the hip and thigh	0.736	0.264
H71 Cholesteatoma of middle ear	0.735	0.265
J30-J39 Other diseases of upper respiratory tract	0.734	0.266
M00-M03 Infectious arthropathies	0.734	0.266
H69 Other disorders of Eustachian tube	0.734	0.266
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.734	0.266
R91 Abnormal findings on diagnostic imaging of lung	0.734	0.266
I77 Other disorders of arteries and arterioles	0.732	0.268
I10-I15 Hypertensive diseases	0.732	0.268
E83.4 Disorders of magnesium metabolism	0.731	0.269
R47-R49 Symptoms and signs involving speech and voice	0.731	0.269
R09.1 Pleurisy	0.730	0.270
R68 Other general symptoms and signs	0.730	0.270
N99-N99 Other disorders of the genitourinary system	0.726	0.274
H61.0 Perichondritis of external ear	0.726	0.274
C26 Malignant neoplasm of other and ill-defined digestive organs	0.725	0.275
J09-J18 Influenza and pneumonia	0.725	0.275
S22 Fracture of rib(s), sternum and thoracic spine	0.720	0.280
N25-N29 Other disorders of kidney and ureter	0.719	0.281
M24.8 Other specific joint derangements, not elsewhere classified	0.719	0.281
N18.9 Chronic renal failure, unspecified	0.719	0.281
H74 Other disorders of middle ear and mastoid	0.718	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
C63 Malignant neoplasm of other and unspecified male genital organs	0.717	0.283
C60 Malignant neoplasm of penis	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
H66.3 Other chronic suppurative otitis media	0.716	0.284
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.716	0.284
M49 Spondylopathies in diseases classified elsewhere	0.714	0.286
J95-J99 Other diseases of the respiratory system	0.713	0.287
D45 Polycythaemia vera	0.713	0.287
E40-E46 Malnutrition	0.712	0.288
S49 Other and unspecified injuries of shoulder and upper arm	0.711	0.289
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
M47.0 Anterior spinal and vertebral artery compression syndromes	0.710	0.290
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.709	0.291
S90-S99 Injuries to the ankle and foot	0.709	0.291
N10-N16 Renal tubulo-interstitial diseases	0.709	0.291
I78 Diseases of capillaries	0.708	0.292
R44.3 Hallucinations, unspecified	0.707	0.293
J35 Chronic diseases of tonsils and adenoids	0.706	0.294
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.706	0.294
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.705	0.295
M47.85 Other spondylosis (Thoracolumbar region)	0.705	0.295
M47.84 Other spondylosis (Thoracic region)	0.705	0.295
M47.83 Other spondylosis (Cervicothoracic region)	0.705	0.295
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.705	0.295
M34 Systemic sclerosis	0.704	0.296
M91-M94 Chondropathies	0.704	0.296
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.703	0.296
R62 Lack of expected normal physiological development	0.703	0.296
R57 Shock, not elsewhere classified	0.703	0.296
R64 Cachexia	0.703	0.296
E83.1 Disorders of iron metabolism	0.703	0.297
H80-H83 Diseases of inner ear	0.702	0.298
R94.5 Abnormal results of liver function studies	0.701	0.299
E16 Other disorders of pancreatic internal secretion	0.701	0.299
N18.5 Chronic kidney disease, stage 5	0.699	0.300
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.699	0.301
M45 Ankylosing spondylitis	0.698	0.302
S42.1 Fracture of scapula	0.696	0.304
S48 Traumatic amputation of shoulder and upper arm	0.695	0.305
S45 Injury of blood vessels at shoulder and upper arm level	0.695	0.305
S44 Injury of nerves at shoulder and upper arm level	0.695	0.305
S41 Open wound of shoulder and upper arm	0.695	0.305
S47 Crushing injury of shoulder and upper arm	0.695	0.305
J81 Pulmonary oedema	0.694	0.306
M35 Other systemic involvement of connective tissue	0.694	0.306
T36-T50 Poisoning by drugs, medicaments and biological substances	0.693	0.307
R04.9 Haemorrhage from respiratory passages, unspecified	0.693	0.307
R04.8 Haemorrhage from other sites in respiratory passages	0.693	0.307
R04.1 Haemorrhage from throat	0.693	0.307
E23 Hypofunction and other disorders of pituitary gland	0.692	0.308
M48.02 Spinal stenosis (Cervical region)	0.692	0.308
I61.5 Intracerebral haemorrhage, intraventricular	0.691	0.309
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.691	0.309
H70 Mastoiditis and related conditions	0.691	0.309
H68 Eustachian salpingitis and obstruction	0.691	0.309
H67 Otitis media in diseases classified elsewhere	0.691	0.309
M54 Dorsalgia	0.690	0.310
R23 Other skin changes	0.690	0.310
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.689	0.311
M33 Dermatopolymyositis	0.689	0.311
M32 Systemic lupus erythematosus	0.689	0.311
M30 Polyarteritis nodosa and related conditions	0.689	0.311
N22 Calculus of urinary tract in diseases classified elsewhere	0.689	0.311
C79.7 Secondary malignant neoplasm of adrenal gland	0.688	0.312
R56.8 Other and unspecified convulsions	0.687	0.313
M53 Other dorsopathies, not elsewhere classified	0.686	0.313
J84 Other interstitial pulmonary diseases	0.685	0.315
R03 Abnormal blood-pressure reading, without diagnosis	0.684	0.316
M80-M85 Disorders of bone density and structure	0.684	0.316
M48.09 Spinal stenosis (Site unspecified)	0.684	0.316
H73 Other disorders of tympanic membrane	0.684	0.316
M51 Other intervertebral disk disorders	0.684	0.316
R73 Elevated blood glucose level	0.683	0.317
R59.1 Generalised enlarged lymph nodes	0.682	0.318
N20.9 Urinary calculus, unspecified	0.681	0.319
M47.99 Spondylosis, unspecified (Site unspecified)	0.681	0.319
C79.8 Secondary malignant neoplasm of other specified sites	0.680	0.320
N05 Unspecified nephritic syndrome	0.680	0.320
J35.1 Hypertrophy of tonsils	0.680	0.320
M50.3 Other cervical disk degeneration	0.680	0.320
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.680	0.320
R45.1 Restlessness and agitation	0.679	0.321
M23.2 Derangement of meniscus due to old tear or injury	0.679	0.321
V80-V89 Other land transport accidents	0.678	0.322
M50.0 Cervical disk disorder with myelopathy	0.678	0.322
R63.0 Anorexia	0.678	0.322
C22.0 Liver cell carcinoma	0.677	0.323
G93 Other disorders of brain	0.677	0.323
R63.8 Other symptoms and signs concerning food and fluid intake	0.677	0.323
C18.9 Colon, unspecified	0.676	0.324
E27.4 Other and unspecified adrenocortical insufficiency	0.676	0.324
R09.3 Abnormal sputum	0.676	0.324
C15.5 Lower third of oesophagus	0.674	0.326
T15-T19 Effects of foreign body entering through natural orifice	0.674	0.326
E87 Other disorders of fluid, electrolyte and acid-base balance	0.674	0.326
S42.9 Fracture of shoulder girdle, part unspecified	0.674	0.326
S42.8 Fracture of other parts of shoulder and upper arm	0.674	0.326
S42.7 Multiple fractures of clavicle, scapula and humerus	0.674	0.326
E83.3 Disorders of phosphorus metabolism	0.674	0.326
M23.5 Chronic instability of knee	0.674	0.326
C62 Malignant neoplasm of testis	0.673	0.327
N18.4 Chronic kidney disease, stage 4	0.673	0.327
S50-S59 Injuries to the elbow and forearm	0.672	0.328
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.672	0.328
W50-W64 Exposure to animate mechanical forces	0.672	0.328
T98 Sequelae of other and unspecified effects of external causes	0.672	0.328
T95 Sequelae of burns, corrosions and frostbite	0.672	0.328
T94 Sequelae of injuries involving multiple and unspecified body regions	0.672	0.328
T91 Sequelae of injuries of neck and trunk	0.672	0.328
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.672	0.328
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.672	0.328
M20 Acquired deformities of fingers and toes	0.672	0.328
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.671	0.329
Chapter I Certain infectious and parasitic diseases	0.671	0.329
M46 Other inflammatory spondylopathies	0.671	0.329
N18.0 End-stage renal disease	0.671	0.329
Q50-Q56 Congenital malformations of genital organs	0.669	0.330
R46 Symptoms and signs involving appearance and behaviour	0.669	0.330
R43 Disturbances of smell and taste	0.669	0.330
N19 Unspecified renal failure	0.669	0.331
I20-I25 Ischaemic heart diseases	0.668	0.332
C09 Malignant neoplasm of tonsil	0.667	0.333
M50.9 Cervical disk disorder, unspecified	0.665	0.335
M50.8 Other cervical disk disorders	0.665	0.335
R07.4 Chest pain, unspecified	0.664	0.336
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.664	0.336
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.664	0.336
C21 Malignant neoplasm of anus and anal canal	0.664	0.336
C17 Malignant neoplasm of small intestine	0.664	0.336
C23 Malignant neoplasm of gallbladder	0.664	0.336
M50.2 Other cervical disk displacement	0.663	0.337
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.663	0.337
R92 Abnormal findings on diagnostic imaging of breast	0.662	0.338
J30 Vasomotor and allergic rhinitis	0.660	0.340
R21 Rash and other nonspecific skin eruption	0.660	0.340
E88 Other metabolic disorders	0.660	0.340
Q20-Q28 Congenital malformations of the circulatory system	0.659	0.341
R52 Pain, not elsewhere classified	0.659	0.341
T79-T79 Certain early complications of trauma	0.659	0.341
M21.3 Wrist or foot drop (acquired)	0.658	0.342
S40 Superficial injury of shoulder and upper arm	0.658	0.342
I72 Other aneurysm	0.658	0.342
R30-R39 Symptoms and signs involving the urinary system	0.658	0.342
H90-H95 Other disorders of ear	0.657	0.343
M86 Osteomyelitis	0.657	0.343
M23.6 Other spontaneous disruption of ligament(s) of knee	0.655	0.344
N02 Recurrent and persistent haematuria	0.655	0.345
S42.21 Fracture of upper end of humerus (open)	0.655	0.345
R32 Unspecified urinary incontinence	0.654	0.346
M47.2 Other spondylosis with radiculopathy	0.652	0.347
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.652	0.348
M48.9 Spondylopathy, unspecified	0.652	0.348
M48.8 Other specified spondylopathies	0.652	0.348
M48.5 Collapsed vertebra, not elsewhere classified	0.652	0.348
M48.4 Fatigue fracture of vertebra	0.652	0.348
M48.3 Traumatic spondylopathy	0.652	0.348
M48.2 Kissing spine	0.652	0.348
M48.1 Ankylosing hyperostosis [Forestier]	0.652	0.348
S32 Fracture of lumbar spine and pelvis	0.652	0.348
S30 Superficial injury of abdomen, lower back and pelvis	0.650	0.350
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.650	0.350
T93.9 Sequelae of unspecified injury of lower limb	0.649	0.350
X40-X49 Accidental poisoning by and exposure to noxious substances	0.648	0.352
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.647	0.353
C71 Malignant neoplasm of brain	0.647	0.353
X60-X84 Intentional self-harm	0.647	0.353
W00-W19 Falls	0.646	0.354
R44.0 Auditory hallucinations	0.646	0.354
R09.2 Respiratory arrest	0.646	0.354
S42.3 Fracture of shaft of humerus	0.645	0.354
R63.5 Abnormal weight gain	0.645	0.355
S42.4 Fracture of lower end of humerus	0.644	0.355
M10 Gout	0.644	0.356
M47.92 Spondylosis, unspecified (Cervical region)	0.643	0.357
E13 Other specified diabetes mellitus	0.643	0.357
E29.1 Testicular hypofunction	0.643	0.357
S46.0 Injury of tendon of the rotator cuff of shoulder	0.643	0.357
E27.2 Addisonian crisis	0.642	0.358
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.642	0.358
E11.4 With neurological complications	0.640	0.360
R05 Cough	0.640	0.360
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.640	0.360
S43.0 Dislocation of shoulder joint	0.639	0.361
G70-G73 Diseases of myoneural junction and muscle	0.637	0.362
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.637	0.363
N08 Glomerular disorders in diseases classified elsewhere	0.636	0.364
H60 Otitis externa	0.636	0.364
M22.4 Chondromalacia patellae	0.636	0.364
E11.2 With renal complications	0.635	0.365
R60.1 Generalised oedema	0.635	0.365
N18.8 Other chronic renal failure	0.634	0.366
N18.1 Chronic kidney disease, stage 1	0.634	0.366
H62 Disorders of external ear in diseases classified elsewhere	0.634	0.366
M22.8 Other disorders of patella	0.634	0.366
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.634	0.366
M24.2 Disorder of ligament	0.633	0.367
Q80-Q89 Other congenital malformations	0.632	0.368
M21.2 Flexion deformity	0.632	0.368
H61.3 Acquired stenosis of external ear canal	0.632	0.368
N40-N51 Diseases of male genital organs	0.632	0.368
I71 Aortic aneurysm and dissection	0.631	0.369
H65.2 Chronic serous otitis media	0.631	0.369
J22 Unspecified acute lower respiratory infection	0.630	0.370
I00-I02 Acute rheumatic fever	0.630	0.370
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.629	0.371
M87.9 Osteonecrosis, unspecified	0.629	0.371
R63.1 Polydipsia	0.629	0.371
M65-M68 Disorders of synovium and tendon	0.629	0.371
D00-D09 In situ neoplasms	0.628	0.372
E16.2 Hypoglycaemia, unspecified	0.627	0.373
R07.0 Pain in throat	0.627	0.373
H66.4 Suppurative otitis media, unspecified	0.626	0.373
H66.2 Chronic atticoantral suppurative otitis media	0.626	0.373
H66.1 Chronic tubotympanic suppurative otitis media	0.626	0.373
H66.0 Acute suppurative otitis media	0.626	0.373
I78.1 Naevus, nonneoplastic	0.627	0.373
C19 Malignant neoplasm of rectosigmoid junction	0.626	0.374
J15 Bacterial pneumonia, not elsewhere classified	0.626	0.374
S80-S89 Injuries to the knee and lower leg	0.626	0.374
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.626	0.374
S02 Fracture of skull and facial bones	0.626	0.374
Q00-Q07 Congenital malformations of the nervous system	0.625	0.374
H61.2 Impacted cerumen	0.625	0.375
R07.2 Precordial pain	0.625	0.375
T90.2 Sequelae of fracture of skull and facial bones	0.625	0.375
J13 Pneumonia due to Streptococcus pneumoniae	0.624	0.375
H65.9 Nonsuppurative otitis media, unspecified	0.624	0.376
R94.3 Abnormal results of cardiovascular function studies	0.624	0.376
R90 Abnormal findings on diagnostic imaging of central nervous system	0.623	0.377
I70 Atherosclerosis	0.623	0.377
C76 Malignant neoplasm of other and ill-defined sites	0.622	0.378
R00 Abnormalities of heart beat	0.622	0.378
T92.1 Sequelae of fracture of arm	0.621	0.379
G80-G83 Cerebral palsy and other paralytic syndromes	0.620	0.380
E35 Disorders of endocrine glands in diseases classified elsewhere	0.620	0.380
E34 Other endocrine disorders	0.620	0.380
E32 Diseases of thymus	0.620	0.380
E31 Polyglandular dysfunction	0.620	0.380
E30 Disorders of puberty, not elsewhere classified	0.620	0.380
E26 Hyperaldosteronism	0.620	0.380
E25 Adrenogenital disorders	0.620	0.380
E24 Cushing's syndrome	0.620	0.380
E22 Hyperfunction of pituitary gland	0.620	0.380
E20 Hypoparathyroidism	0.620	0.380
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.620	0.380
J84.1 Other interstitial pulmonary diseases with fibrosis	0.619	0.381
S19 Other and unspecified injuries of neck	0.618	0.382
E50-E64 Other nutritional deficiencies	0.617	0.383
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.617	0.383
M23.9 Internal derangement of knee, unspecified	0.616	0.383
M23.1 Discoid meniscus (congenital)	0.616	0.383
M23.0 Cystic meniscus	0.616	0.383
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.616	0.384
E27.1 Primary adrenocortical insufficiency	0.616	0.384
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.616	0.384
R44.2 Other hallucinations	0.616	0.384
R61 Hyperhidrosis	0.616	0.384
S42.00 Fracture of clavicle (closed)	0.616	0.384
S12 Fracture of neck	0.616	0.384
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.615	0.385
C18.4 Transverse colon	0.615	0.385
E80 Disorders of porphyrin and bilirubin metabolism	0.613	0.386
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.612	0.387
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.612	0.388
G00-G09 Inflammatory diseases of the central nervous system	0.612	0.388
I77.1 Stricture of artery	0.611	0.389
M90 Osteopathies in diseases classified elsewhere	0.611	0.389
H72.0 Central perforation of tympanic membrane	0.610	0.390
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.610	0.390
Y35-Y36 Legal intervention and operations of war	0.610	0.390
Y10-Y34 Event of undetermined intent	0.610	0.390
Y00-Y09 Assault	0.610	0.390
X85-X99 Assault	0.610	0.390
X58-X59 Accidental exposure to other and unspecified factors	0.610	0.390
X50-X57 Overexertion, travel and privation	0.610	0.390
X30-X39 Exposure to forces of nature	0.610	0.390
X20-X29 Contact with venomous animals and plants	0.610	0.390
X10-X19 Contact with heat and hot substances	0.610	0.390
X00-X09 Exposure to smoke, fire and flames	0.610	0.390
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.610	0.390
W75-W84 Other accidental threats to breathing	0.610	0.390
W65-W74 Accidental drowning and submersion	0.610	0.390
V98-V99 Other and unspecified transport accidents	0.610	0.390
V95-V97 Air and space transport accidents	0.610	0.390
V90-V94 Water transport accidents	0.610	0.390
V70-V79 Bus occupant injured in transport accident	0.610	0.390
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.610	0.390
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.610	0.390
V40-V49 Car occupant injured in transport accident	0.610	0.390
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.610	0.390
V01-V09 Pedestrian injured in transport accident	0.610	0.390
M24.1 Other articular cartilage disorders	0.610	0.390
E85 Amyloidosis	0.610	0.390
E84 Cystic fibrosis	0.610	0.390
E79 Disorders of purine and pyrimidine metabolism	0.610	0.390
E77 Disorders of glycoprotein metabolism	0.610	0.390
E76 Disorders of glycosaminoglycan metabolism	0.610	0.390
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.610	0.390
E74 Other disorders of carbohydrate metabolism	0.610	0.390
E73 Lactose intolerance	0.610	0.390
E72 Other disorders of amino-acid metabolism	0.610	0.390
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.610	0.390
E70 Disorders of aromatic amino-acid metabolism	0.610	0.390
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.610	0.390
C18.0 Caecum	0.610	0.390
S09 Other and unspecified injuries of head	0.609	0.391
I95-I99 Other and unspecified disorders of the circulatory system	0.609	0.391
R50 Fever of unknown origin	0.609	0.391
C78.2 Secondary malignant neoplasm of pleura	0.609	0.391
S20 Superficial injury of thorax	0.608	0.392
C69 Malignant neoplasm of eye and adnexa	0.608	0.392
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.607	0.392
Q35-Q37 Cleft lip and cleft palate	0.607	0.392
Q30-Q34 Congenital malformations of the respiratory system	0.607	0.392
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.607	0.392
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.607	0.393
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.607	0.393
M48.05 Spinal stenosis (Thoracolumbar region)	0.607	0.393
M48.04 Spinal stenosis (Thoracic region)	0.607	0.393
M48.03 Spinal stenosis (Cervicothoracic region)	0.607	0.393
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.607	0.393
M48.00 Spinal stenosis (Multiple sites in spine)	0.607	0.393
H72.8 Other perforations of tympanic membrane	0.607	0.393
H72.2 Other marginal perforations of tympanic membrane	0.607	0.393
H72.1 Attic perforation of tympanic membrane	0.607	0.393
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.606	0.394
E11.0 With coma	0.606	0.394
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.606	0.394
I61.9 Intracerebral haemorrhage, unspecified	0.605	0.395
C51-C58 Malignant neoplasms of female genital organs	0.605	0.395
I69 Sequelae of cerebrovascular disease	0.605	0.395
M88 Paget's disease of bone [osteitis deformans]	0.604	0.396
S06 Intracranial injury	0.604	0.396
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.604	0.396
R09.0 Asphyxia	0.603	0.397
J98 Other respiratory disorders	0.603	0.397

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations