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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72668436
log Bayes Factor = 5.13152
Chromosome 8   position 99,917,181  (GRCh37) Explore rs72668436 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
M47 Spondylosis
0.995 0.005 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
I20-I25 Ischaemic heart diseases
0.991 0.009 0.000
E11 Non-insulin-dependent diabetes mellitus
0.988 0.012 0.000
M47.8 Other spondylosis
0.988 0.012 0.000
S20-S29 Injuries to the thorax
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
I25 Chronic ischaemic heart disease
0.977 0.023 0.000
I49 Other cardiac arrhythmias
0.975 0.025 0.000
I34 Nonrheumatic mitral valve disorders
0.975 0.025 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
E11.9 Without complications
0.971 0.029 0.000
M80-M85 Disorders of bone density and structure
0.970 0.030 0.000
I20 Angina pectoris
0.966 0.034 0.000
M47.82 Other spondylosis (Cervical region)
0.962 0.038 0.000
I51 Complications and ill-defined descriptions of heart disease
0.951 0.049 0.000
I20.0 Unstable angina
0.950 0.050 0.000
E86 Volume depletion
0.949 0.051 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.944 0.056 0.000
I51.7 Cardiomegaly
0.934 0.066 0.000
I44 Atrioventricular and left bundle-branch block
0.933 0.067 0.000
I25.1 Atherosclerotic heart disease
0.925 0.075 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.924 0.076 0.000
I34.1 Mitral (valve) prolapse
0.923 0.077 0.000
I50 Heart failure
0.921 0.079 0.000
M50-M54 Other dorsopathies
0.920 0.080 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.917 0.083 0.000
S00-S09 Injuries to the head
0.916 0.084 0.000
I49.9 Cardiac arrhythmia, unspecified
0.912 0.088 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.912 0.088 0.000
S21 Open wound of thorax
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
E11.3 With ophthalmic complications
0.902 0.098 0.000
S22.4 Multiple fractures of ribs
0.902 0.098 0.000
M84 Disorders of continuity of bone
0.901 0.099 0.000
W20-W49 Exposure to inanimate mechanical forces
0.899 0.101 0.000
M65-M68 Disorders of synovium and tendon
0.894 0.106 0.000
M54 Dorsalgia
0.891 0.109 0.000
M46 Other inflammatory spondylopathies
0.891 0.109 0.000
I50.9 Heart failure, unspecified
0.885 0.115 0.000
T79-T79 Certain early complications of trauma
0.884 0.116 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.883 0.117 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.881 0.119 0.000
S22.40 Multiple fractures of ribs (closed)
0.872 0.128 0.000
M47.89 Other spondylosis (Site unspecified)
0.867 0.133 0.000
I20.9 Angina pectoris, unspecified
0.865 0.135 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.858 0.142 0.000
I34.0 Mitral (valve) insufficiency
0.853 0.147 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.852 0.148 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.850 0.150 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.845 0.155 0.000
M47.1 Other spondylosis with myelopathy
0.839 0.161 0.000
E65-E68 Obesity and other hyperalimentation
0.839 0.161 0.000
I30 Acute pericarditis
0.835 0.165 0.000
I49.0 Ventricular fibrillation and flutter
0.831 0.169 0.000
S27 Injury of other and unspecified intrathoracic organs
0.826 0.174 0.000
E11.2 With renal complications
0.823 0.177 0.000
V10-V19 Pedal cyclist injured in transport accident
0.823 0.177 0.000
T66-T78 Other and unspecified effects of external causes
0.822 0.178 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.822 0.178 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.821 0.179 0.000
M47.2 Other spondylosis with radiculopathy
0.818 0.182 0.000
I25.5 Ischaemic cardiomyopathy
0.816 0.184 0.000
E80.4 Gilbert's syndrome
0.816 0.184 0.000
I42 Cardiomyopathy
0.814 0.186 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.813 0.187 0.000
S02 Fracture of skull and facial bones
0.810 0.190 0.000
M85 Other disorders of bone density and structure
0.809 0.191 0.000
M54.2 Cervicalgia
0.807 0.193 0.000
E88 Other metabolic disorders
0.806 0.194 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.806 0.194 0.000
S21.2 Open wound of back wall of thorax
0.806 0.194 0.000
I49.3 Ventricular premature depolarisation
0.805 0.195 0.000
M54.5 Low back pain
0.805 0.195 0.000
I44.0 Atrioventricular block, first degree
0.803 0.197 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.802 0.198 0.000
I44.7 Left bundle-branch block, unspecified
0.802 0.198 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.801 0.199 0.000
E85 Amyloidosis
0.800 0.200 0.000
I37 Pulmonary valve disorders
0.797 0.202 0.000
M45 Ankylosing spondylitis
0.796 0.204 0.000
I33 Acute and subacute endocarditis
0.793 0.207 0.000
I25.3 Aneurysm of heart
0.792 0.208 0.000
Y57 Other and unspecified drugs and medicaments
0.790 0.210 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.790 0.210 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.790 0.210 0.000
S00 Superficial injury of head
0.788 0.212 0.000
M80 Osteoporosis with pathological fracture
0.787 0.212 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.785 0.215 0.000
X50-X57 Overexertion, travel and privation
0.785 0.215 0.000
S32 Fracture of lumbar spine and pelvis
0.784 0.216 0.000
S10-S19 Injuries to the neck
0.781 0.219 0.000
I44.6 Other and unspecified fascicular block
0.779 0.221 0.000
S21.1 Open wound of front wall of thorax
0.777 0.223 0.000
E11.1 With ketoacidosis
0.776 0.224 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.776 0.224 0.000
I44.2 Atrioventricular block, complete
0.775 0.225 0.000
I49.1 Atrial premature depolarisation
0.774 0.226 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.774 0.226 0.000
M47.9 Spondylosis, unspecified
0.772 0.228 0.000
W75-W84 Other accidental threats to breathing
0.772 0.228 0.000
I49.5 Sick sinus syndrome
0.770 0.230 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.769 0.231 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.769 0.231 0.000
M54.56 Low back pain (Lumbar region)
0.767 0.233 0.000
T86 Failure and rejection of transplanted organs and tissues
0.767 0.233 0.000
E14 Unspecified diabetes mellitus
0.767 0.233 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.767 0.233 0.000
S22.3 Fracture of rib
0.765 0.235 0.000
E11.0 With coma
0.764 0.236 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.763 0.237 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.762 0.238 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.761 0.239 0.000
W00-W19 Falls
0.759 0.241 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.758 0.241 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.756 0.244 0.000
S31 Open wound of abdomen, lower back and pelvis
0.756 0.244 0.000
E13 Other specified diabetes mellitus
0.756 0.244 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.756 0.244 0.000
M82 Osteoporosis in diseases classified elsewhere
0.755 0.245 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
Chapter VI Diseases of the nervous system
0.754 0.246 0.000
V20-V29 Motorcycle rider injured in transport accident
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.752 0.248 0.000
M67 Other disorders of synovium and tendon
0.752 0.248 0.000
M47.86 Other spondylosis (Lumbar region)
0.748 0.252 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.748 0.252 0.000
M54.22 Cervicalgia (Cervical region)
0.747 0.253 0.000
E16 Other disorders of pancreatic internal secretion
0.747 0.253 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.746 0.254 0.000
W25 Contact with sharp glass
0.744 0.256 0.000
Q60-Q64 Congenital malformations of the urinary system
0.744 0.256 0.000
Y00-Y09 Assault
0.743 0.257 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.736 0.264 0.000
W20 Struck by thrown, projected or falling object
0.736 0.264 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.734 0.266 0.000
T00-T07 Injuries involving multiple body regions
0.733 0.266 0.000
M65 Synovitis and tenosynovitis
0.732 0.268 0.000
W44 Foreign body entering into or through eye or natural orifice
0.730 0.269 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.730 0.270 0.000
I36 Nonrheumatic tricuspid valve disorders
0.730 0.270 0.000
M48 Other spondylopathies
0.730 0.270 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.727 0.273 0.000
E66 Obesity
0.725 0.275 0.000
S22.1 Multiple fractures of thoracic spine
0.724 0.276 0.000
T78 Adverse effects, not elsewhere classified
0.721 0.279 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.721 0.279 0.000
S27.0 Traumatic pneumothorax
0.721 0.279 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.721 0.279 0.000
S36 Injury of intra-abdominal organs
0.720 0.280 0.000
S20 Superficial injury of thorax
0.720 0.280 0.000
Y40 Systemic antibiotics
0.719 0.281 0.000
I22 Subsequent myocardial infarction
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
I30.9 Acute pericarditis, unspecified
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
E11.5 With peripheral circulatory complications
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
I23 Certain current complications following acute myocardial infarction
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.710 0.290 0.000
E11.8 With unspecified complications
0.708 0.292 0.000
E11.7 With multiple complications
0.708 0.292 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.708 0.292 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.708 0.292 0.000
M47.84 Other spondylosis (Thoracic region)
0.708 0.292 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.708 0.292 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.708 0.292 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.708 0.292 0.000
S26 Injury of heart
0.708 0.292 0.000
S25 Injury of blood vessels of thorax
0.708 0.292 0.000
S24 Injury of nerves and spinal cord at thorax level
0.708 0.292 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
Chapter II Neoplasms
0.707 0.293 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.706 0.294 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
I25.6 Silent myocardial ischaemia
0.700 0.300 0.000
I25.4 Coronary artery aneurysm
0.700 0.300 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.700 0.300 0.000
S80-S89 Injuries to the knee and lower leg
0.700 0.300 0.000
I49.2 Junctional premature depolarisation
0.699 0.301 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.699 0.301 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.699 0.301 0.000
S22.5 Flail chest
0.699 0.301 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
M83 Adult osteomalacia
0.695 0.305 0.000
S02.1 Fracture of base of skull
0.694 0.305 0.000
M54.9 Dorsalgia, unspecified
0.694 0.306 0.000
I50.0 Congestive heart failure
0.694 0.306 0.000
Y57.5 X-ray contrast media
0.693 0.307 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.692 0.308 0.000
C15-C26 Malignant neoplasms of digestive organs
0.691 0.309 0.000
Y52 Agents primarily affecting the cardiovascular system
0.691 0.309 0.000
M81 Osteoporosis without pathological fracture
0.691 0.309 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.690 0.310 0.000
S01 Open wound of head
0.690 0.310 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.690 0.310 0.000
M54.3 Sciatica
0.689 0.311 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.688 0.312 0.000
M85.8 Other specified disorders of bone density and structure
0.687 0.313 0.000
S05 Injury of eye and orbit
0.687 0.313 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.685 0.315 0.000
S22.0 Fracture of thoracic vertebra
0.685 0.315 0.000
D72 Other disorders of white blood cells
0.684 0.316 0.000
I51.6 Cardiovascular disease, unspecified
0.682 0.318 0.000
I51.5 Myocardial degeneration
0.682 0.318 0.000
I51.4 Myocarditis, unspecified
0.682 0.318 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.682 0.318 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.682 0.318 0.000
I51.0 Cardiac septal defect, acquired
0.682 0.318 0.000
M66 Spontaneous rupture of synovium and tendon
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.682 0.318 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
D73 Diseases of spleen
0.680 0.320 0.000
S02.8 Fractures of other skull and facial bones
0.679 0.320 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.677 0.323 0.000
S22.9 Fracture of bony thorax, part unspecified
0.677 0.323 0.000
S22.8 Fracture of other parts of bony thorax
0.677 0.323 0.000
E85.4 Organ-limited amyloidosis
0.677 0.323 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.676 0.324 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.674 0.326 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.674 0.326 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.673 0.327 0.000
T79.7 Traumatic subcutaneous emphysema
0.672 0.328 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.672 0.328 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.672 0.328 0.000
I44.5 Left posterior fascicular block
0.669 0.331 0.000
I44.4 Left anterior fascicular block
0.669 0.331 0.000
Q50-Q56 Congenital malformations of genital organs
0.669 0.331 0.000
M67.8 Other specified disorders of synovium and tendon
0.668 0.332 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.333 0.000
M91-M94 Chondropathies
0.667 0.333 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.666 0.334 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.666 0.334 0.000
S06 Intracranial injury
0.665 0.335 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.663 0.337 0.000
S37 Injury of urinary and pelvic organs
0.663 0.337 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.663 0.337 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.663 0.337 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.663 0.337 0.000
E11.4 With neurological complications
0.662 0.337 0.000
I42.2 Other hypertrophic cardiomyopathy
0.661 0.339 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
M54.1 Radiculopathy
0.659 0.341 0.000
E16.2 Hypoglycaemia, unspecified
0.659 0.341 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.658 0.342 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.657 0.343 0.000
M40-M43 Deforming dorsopathies
0.657 0.343 0.000
S08 Traumatic amputation of part of head
0.656 0.343 0.000
S07 Crushing injury of head
0.656 0.343 0.000
S04 Injury of cranial nerves
0.656 0.343 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.656 0.343 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.656 0.344 0.000
I49.4 Other and unspecified premature depolarisation
0.656 0.344 0.000
C20 Malignant neoplasm of rectum
0.656 0.344 0.000
C01 Malignant neoplasm of base of tongue
0.656 0.344 0.000
I38 Endocarditis, valve unspecified
0.655 0.345 0.000
I74 Arterial embolism and thrombosis
0.655 0.345 0.000
M84.0 Malunion of fracture
0.655 0.345 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Y58 Bacterial vaccines
0.654 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.654 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.654 0.346 0.000
S21.9 Open wound of thorax, part unspecified
0.653 0.347 0.000
S21.8 Open wound of other parts of thorax
0.653 0.347 0.000
S21.7 Multiple open wounds of thoracic wall
0.653 0.347 0.000
S21.0 Open wound of breast
0.653 0.347 0.000
I37.1 Pulmonary valve insufficiency
0.653 0.347 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.652 0.348 0.000
S01.5 Open wound of lip and oral cavity
0.651 0.349 0.000
Y65 Other misadventures during surgical and medical care
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
E11.6 With other specified complications
0.650 0.349 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.650 0.350 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
M54.50 Low back pain (Multiple sites in spine)
0.647 0.353 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.647 0.353 0.000
S22.41 Multiple fractures of ribs (open)
0.647 0.353 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.646 0.354 0.000
M84.9 Disorder of continuity of bone, unspecified
0.646 0.354 0.000
M84.8 Other disorders of continuity of bone
0.646 0.354 0.000
M84.4 Pathological fracture, not elsewhere classified
0.646 0.354 0.000
M84.3 Stress fracture, not elsewhere classified
0.646 0.354 0.000
M84.2 Delayed union of fracture
0.646 0.354 0.000
X51 Travel and motion
0.645 0.355 0.000
I33.0 Acute and subacute infective endocarditis
0.645 0.355 0.000
S00.9 Superficial injury of head, part unspecified
0.645 0.355 0.000
W46 Contact with hypodermic needle
0.645 0.355 0.000
W45 Foreign body or object entering through skin
0.645 0.355 0.000
W43 Exposure to vibration
0.645 0.355 0.000
W42 Exposure to noise
0.645 0.355 0.000
W41 Exposure to high-pressure jet
0.645 0.355 0.000
W40 Explosion of other materials
0.645 0.355 0.000
W39 Discharge of firework
0.645 0.355 0.000
W38 Explosion and rupture of other specified pressurised devices
0.645 0.355 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.645 0.355 0.000
W36 Explosion and rupture of gas cylinder
0.645 0.355 0.000
W35 Explosion and rupture of boiler
0.645 0.355 0.000
W34 Discharge from other and unspecified firearms
0.645 0.355 0.000
W33 Rifle, shotgun and larger firearm discharge
0.645 0.355 0.000
W32 Handgun discharge
0.645 0.355 0.000
W31 Contact with other and unspecified machinery
0.645 0.355 0.000
W30 Contact with agricultural machinery
0.645 0.355 0.000
W28 Contact with powered lawn mower
0.645 0.355 0.000
W27 Contact with nonpowered hand tool
0.645 0.355 0.000
W26 Contact with knife, sword or dagger
0.645 0.355 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.645 0.355 0.000
W21 Striking against or struck by sports equipment
0.645 0.355 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.644 0.356 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.643 0.356 0.000
T18 Foreign body in alimentary tract
0.641 0.359 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.641 0.359 0.000
M54.8 Other dorsalgia
0.639 0.361 0.000
M54.0 Panniculitis affecting regions of neck and back
0.639 0.361 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.639 0.361 0.000
M46.8 Other specified inflammatory spondylopathies
0.638 0.361 0.000
M46.5 Other infective spondylopathies
0.638 0.361 0.000
M46.4 Discitis, unspecified
0.638 0.361 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.638 0.361 0.000
M46.2 Osteomyelitis of vertebra
0.638 0.361 0.000
M46.0 Spinal enthesopathy
0.638 0.361 0.000
S00.0 Superficial injury of scalp
0.638 0.362 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.638 0.362 0.000
I42.6 Alcoholic cardiomyopathy
0.638 0.362 0.000
Q00-Q07 Congenital malformations of the nervous system
0.637 0.362 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.636 0.364 0.000
S22.30 Fracture of rib (closed)
0.636 0.364 0.000
Q76 Congenital malformations of spine and bony thorax
0.636 0.364 0.000
E87.3 Alkalosis
0.636 0.364 0.000
T17 Foreign body in respiratory tract
0.635 0.365 0.000
T58 Toxic effect of carbon monoxide
0.635 0.365 0.000
G57 Mononeuropathies of lower limb
0.635 0.365 0.000
S32.5 Fracture of pubis
0.634 0.366 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.633 0.367 0.000
W25.9 Unspecified place
0.633 0.367 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.633 0.367 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.633 0.367 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.632 0.367 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.632 0.368 0.000
E80.6 Other disorders of bilirubin metabolism
0.632 0.368 0.000
E80.5 Crigler-Najjar syndrome
0.632 0.368 0.000
E80.3 Defects of catalase and peroxydase
0.632 0.368 0.000
E80.2 Other porphyria
0.632 0.368 0.000
E80.1 Porphyria cutanea tarda
0.632 0.368 0.000
E80.0 Hereditary erythropoietic porphyria
0.632 0.368 0.000
S02.4 Fracture of malar and maxillary bones
0.631 0.369 0.000
S12 Fracture of neck
0.631 0.369 0.000
W22 Striking against or struck by other objects
0.630 0.370 0.000
T86.0 Bone-marrow transplant rejection
0.630 0.370 0.000
T79.6 Traumatic ischaemia of muscle
0.629 0.371 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.628 0.372 0.000
D55-D59 Haemolytic anaemias
0.628 0.372 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.627 0.372 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.627 0.373 0.000
D73.0 Hyposplenism
0.626 0.374 0.000
S90-S99 Injuries to the ankle and foot
0.625 0.375 0.000
T78.3 Angioneurotic oedema
0.625 0.375 0.000
T87 Complications peculiar to reattachment and amputation
0.625 0.375 0.000
D72.8 Other specified disorders of white blood cells
0.625 0.375 0.000
W84 Unspecified threat to breathing
0.624 0.376 0.000
M54.4 Lumbago with sciatica
0.624 0.376 0.000
S00.1 Contusion of eyelid and periocular area
0.623 0.377 0.000
S89 Other and unspecified injuries of lower leg
0.622 0.378 0.000
M51 Other intervertebral disk disorders
0.622 0.378 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.621 0.379 0.000
S00.5 Superficial injury of lip and oral cavity
0.620 0.380 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.620 0.380 0.000
S32.3 Fracture of ilium
0.620 0.380 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.619 0.380 0.000
W20.0 Home
0.619 0.381 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.618 0.381 0.000
T43.2 Other and unspecified antidepressants
0.617 0.383 0.000
I42.8 Other cardiomyopathies
0.616 0.384 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.615 0.385 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.615 0.385 0.000
S02.7 Multiple fractures involving skull and facial bones
0.614 0.386 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.613 0.387 0.000
C10 Malignant neoplasm of oropharynx
0.612 0.388 0.000
M89 Other disorders of bone
0.612 0.388 0.000
S02.10 Fracture of base of skull (closed)
0.612 0.388 0.000
M53 Other dorsopathies, not elsewhere classified
0.611 0.389 0.000
D66 Hereditary factor VIII deficiency
0.611 0.389 0.000
E15 Nondiabetic hypoglycaemic coma
0.611 0.389 0.000
W44.0 Home
0.610 0.390 0.000
T36 Poisoning by systemic antibiotics
0.609 0.391 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.609 0.391 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.609 0.391 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.609 0.391 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.609 0.391 0.000
T82.1 Mechanical complication of cardiac electronic device
0.609 0.391 0.000
G58 Other mononeuropathies
0.609 0.391 0.000
I51.8 Other ill-defined heart diseases
0.608 0.392 0.000
S02.5 Fracture of tooth
0.607 0.392 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.607 0.393 0.000
E66.9 Obesity, unspecified
0.607 0.393 0.000
S27.3 Other injuries of lung
0.606 0.394 0.000
Chapter VIII Diseases of the ear and mastoid process
0.606 0.394 0.000
I25.2 Old myocardial infarction
0.605 0.395 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.605 0.395 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.604 0.396 0.000
E14.9 Without complications
0.604 0.396 0.000
W05 Fall involving wheelchair
0.602 0.398 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.602 0.398 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.602 0.398 0.000
W18 Other fall on same level
0.602 0.398 0.000
M82.1 Osteoporosis in endocrine disorders
0.602 0.398 0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.602 0.398 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.602 0.398 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.602 0.398 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.602 0.398 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.602 0.398 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.602 0.398 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.602 0.398 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.602 0.398 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.602 0.398 0.000
E67 Other hyperalimentation
0.601 0.398 0.000
E68 Sequelae of hyperalimentation
0.601 0.398 0.000
E65 Localised adiposity
0.601 0.398 0.000
D80-D89 Certain disorders involving the immune mechanism
0.601 0.399 0.000
S70 Superficial injury of hip and thigh
0.601 0.399 0.000
S31.8 Open wound of other and unspecified parts of abdomen
0.600 0.400 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.599 0.401 0.000
I30.8 Other forms of acute pericarditis
0.598 0.401 0.000
I30.1 Infective pericarditis
0.598 0.401 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.598 0.401 0.000
W13 Fall from, out of or through building or structure
0.598 0.401 0.000
S02.0 Fracture of vault of skull
0.598 0.402 0.000
M54.6 Pain in thoracic spine
0.597 0.403 0.000
I20.1 Angina pectoris with documented spasm
0.596 0.403 0.000
S11 Open wound of neck
0.596 0.404 0.000
G54 Nerve root and plexus disorders
0.596 0.404 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.596 0.404 0.000
M54.57 Low back pain (Lumbosacral region)
0.596 0.404 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.596 0.404 0.000
S32.4 Fracture of acetabulum
0.595 0.404 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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