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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75729198
log Bayes Factor = 19.6792
Chromosome 8   position 15,885,087  (GRCh37) Explore rs75729198 on Ensembl!
Variant rs75729198 is part of Cluster X0068

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.997 0.003 0.000
S50-S59 Injuries to the elbow and forearm
0.996 0.004 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
S52 Fracture of forearm
0.993 0.007 0.000
Z85 Personal history of malignant neoplasm
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
Z50 Care involving use of rehabilitation procedures
0.986 0.014 0.000
S52.5 Fracture of lower end of radius
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.984 0.016 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.984 0.016 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.977 0.023 0.000
N40-N51 Diseases of male genital organs
0.975 0.025 0.000
S52.50 Fracture of lower end of radius (closed)
0.975 0.025 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.971 0.029 0.000
R30-R39 Symptoms and signs involving the urinary system
0.970 0.030 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.970 0.030 0.000
N40 Hyperplasia of prostate
0.970 0.030 0.000
M20-M25 Other joint disorders
0.969 0.031 0.000
Z87 Personal history of other diseases and conditions
0.969 0.031 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.965 0.035 0.000
Chapter I Certain infectious and parasitic diseases
0.963 0.037 0.000
Z50.8 Care involving use of rehabilitation procedures
0.960 0.040 0.000
Z87.1 Personal history of diseases of the digestive system
0.959 0.041 0.000
Chapter II Neoplasms
0.956 0.044 0.000
Z88.0 Personal history of allergy to penicillin
0.952 0.048 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.945 0.055 0.000
M35 Other systemic involvement of connective tissue
0.942 0.058 0.000
R33 Retention of urine
0.939 0.061 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.936 0.064 0.000
E83 Disorders of mineral metabolism
0.933 0.067 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.932 0.068 0.000
Z46 Fitting and adjustment of other devices
0.932 0.068 0.000
R39 Other symptoms and signs involving the urinary system
0.929 0.071 0.000
S52.6 Fracture of lower end of both ulna and radius
0.929 0.071 0.000
Z50.1 Other physical therapy
0.928 0.072 0.000
E86 Volume depletion
0.924 0.076 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.922 0.078 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.920 0.080 0.000
M35.3 Polymyalgia rheumatica
0.919 0.081 0.000
M45-M49 Spondylopathies
0.919 0.081 0.000
S00-S09 Injuries to the head
0.916 0.084 0.000
N10-N16 Renal tubulo-interstitial diseases
0.916 0.084 0.000
N60-N64 Disorders of breast
0.904 0.096 0.000
Z90.7 Acquired absence of genital organ(s)
0.904 0.096 0.000
M50-M54 Other dorsopathies
0.904 0.096 0.000
A30-A49 Other bacterial diseases
0.902 0.098 0.000
M25 Other joint disorders, not elsewhere classified
0.894 0.106 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.891 0.109 0.000
Z93 Artificial opening status
0.889 0.111 0.000
Chapter X Diseases of the respiratory system
0.889 0.111 0.000
Chapter XX External causes of morbidity and mortality
0.888 0.112 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.883 0.117 0.000
M05-M14 Inflammatory polyarthropathies
0.878 0.122 0.000
R30 Pain associated with micturition
0.873 0.127 0.000
Z42 Follow-up care involving plastic surgery
0.871 0.129 0.000
E83.5 Disorders of calcium metabolism
0.871 0.129 0.000
Z04 Examination and observation for other reasons
0.868 0.132 0.000
C50-C50 Malignant neoplasm of breast
0.868 0.132 0.000
R39.1 Other difficulties with micturition
0.868 0.132 0.000
N17-N19 Renal failure
0.868 0.132 0.000
Z53.9 Procedure not carried out, unspecified reason
0.867 0.133 0.000
M48 Other spondylopathies
0.867 0.133 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.862 0.138 0.000
Z46.6 Fitting and adjustment of urinary device
0.859 0.141 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.858 0.142 0.000
Z29 Need for other prophylactic measures
0.856 0.144 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.854 0.146 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.849 0.151 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.847 0.153 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.844 0.156 0.000
Z88.2 Personal history of allergy to sulphonamides
0.844 0.156 0.000
R50-R69 General symptoms and signs
0.843 0.157 0.000
Chapter XI Diseases of the digestive system
0.842 0.158 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.842 0.158 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.837 0.163 0.000
S70-S79 Injuries to the hip and thigh
0.836 0.164 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.834 0.165 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.832 0.168 0.000
S52.51 Fracture of lower end of radius (open)
0.832 0.168 0.000
K50-K52 Noninfective enteritis and colitis
0.832 0.168 0.000
Z94 Transplanted organ and tissue status
0.830 0.170 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.830 0.170 0.000
M48.0 Spinal stenosis
0.829 0.171 0.000
M40-M43 Deforming dorsopathies
0.829 0.171 0.000
A41 Other septicaemia
0.829 0.171 0.000
E50-E64 Other nutritional deficiencies
0.827 0.173 0.000
M54 Dorsalgia
0.826 0.174 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.824 0.176 0.000
Z80 Family history of malignant neoplasm
0.824 0.176 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.821 0.179 0.000
C64-C68 Malignant neoplasms of urinary tract
0.821 0.179 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.821 0.179 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.816 0.184 0.000
R31 Unspecified haematuria
0.815 0.185 0.000
S40-S49 Injuries to the shoulder and upper arm
0.814 0.186 0.000
N19 Unspecified renal failure
0.814 0.186 0.000
R63 Symptoms and signs concerning food and fluid intake
0.810 0.190 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.810 0.190 0.000
S01 Open wound of head
0.808 0.192 0.000
E20-E35 Disorders of other endocrine glands
0.808 0.192 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.806 0.194 0.000
N62 Hypertrophy of breast
0.806 0.194 0.000
C50 Malignant neoplasm of breast
0.805 0.195 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.805 0.195 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.804 0.196 0.000
E83.4 Disorders of magnesium metabolism
0.804 0.196 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.800 0.200 0.000
M48.06 Spinal stenosis (Lumbar region)
0.800 0.200 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.797 0.203 0.000
N42 Other disorders of prostate
0.794 0.206 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.794 0.206 0.000
K52 Other non-infective gastro-enteritis and colitis
0.793 0.207 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.792 0.208 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.792 0.208 0.000
Z93.6 Other artificial openings of urinary tract status
0.791 0.209 0.000
J30-J39 Other diseases of upper respiratory tract
0.791 0.209 0.000
K50 Crohn's disease [regional enteritis]
0.790 0.210 0.000
C44 Other malignant neoplasms of skin
0.789 0.211 0.000
Z93.5 Cystostomy status
0.789 0.211 0.000
M25.5 Pain in joint
0.789 0.211 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.787 0.212 0.000
E88 Other metabolic disorders
0.787 0.213 0.000
E85 Amyloidosis
0.787 0.213 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.785 0.215 0.000
Z22 Carrier of infectious disease
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.782 0.218 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.781 0.218 0.000
J09-J18 Influenza and pneumonia
0.781 0.219 0.000
S80-S89 Injuries to the knee and lower leg
0.780 0.220 0.000
S60-S69 Injuries to the wrist and hand
0.777 0.223 0.000
B25-B34 Other viral diseases
0.777 0.223 0.000
Z83 Family history of other specific disorders
0.776 0.224 0.000
Z54 Convalescence
0.775 0.225 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.775 0.225 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.774 0.226 0.000
J95-J99 Other diseases of the respiratory system
0.774 0.226 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.771 0.229 0.000
C67 Malignant neoplasm of bladder
0.771 0.229 0.000
B95-B98 Bacterial, viral and other infectious agents
0.771 0.229 0.000
D10-D36 Benign neoplasms
0.767 0.233 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.767 0.233 0.000
N99-N99 Other disorders of the genitourinary system
0.767 0.233 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.766 0.234 0.000
Z97 Presence of other devices
0.765 0.235 0.000
N43 Hydrocele and spermatocele
0.765 0.235 0.000
R30.0 Dysuria
0.764 0.236 0.000
T42.4 Benzodiazepines
0.762 0.238 0.000
R60 Oedema, not elsewhere classified
0.762 0.238 0.000
S00 Superficial injury of head
0.762 0.238 0.000
C51-C58 Malignant neoplasms of female genital organs
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
K50.9 Crohn's disease, unspecified
0.754 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.754 0.246 0.000
A00-A09 Intestinal infectious diseases
0.754 0.246 0.000
M80-M85 Disorders of bone density and structure
0.753 0.247 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.753 0.247 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.752 0.248 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.751 0.249 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.750 0.249 0.000
M91-M94 Chondropathies
0.750 0.250 0.000
M25.7 Osteophyte
0.748 0.252 0.000
M34 Systemic sclerosis
0.747 0.253 0.000
M21 Other acquired deformities of limbs
0.746 0.254 0.000
M06 Other rheumatoid arthritis
0.745 0.255 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.745 0.255 0.000
R53 Malaise and fatigue
0.744 0.256 0.000
Z49 Care involving dialysis
0.744 0.256 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.744 0.256 0.000
B15-B19 Viral hepatitis
0.744 0.256 0.000
Z29.2 Other prophylactic chemotherapy
0.741 0.259 0.000
Z90.8 Acquired absence of other organs
0.741 0.259 0.000
C50.2 Upper-inner quadrant of breast
0.741 0.259 0.000
M00-M03 Infectious arthropathies
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
N25-N29 Other disorders of kidney and ureter
0.739 0.261 0.000
R63.4 Abnormal weight loss
0.738 0.262 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.738 0.262 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.737 0.262 0.000
Z90.2 Acquired absence of lung [part of]
0.735 0.265 0.000
Z29.1 Prophylactic immunotherapy
0.735 0.265 0.000
Z74 Problems related to care-provider dependency
0.735 0.265 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.735 0.265 0.000
Z88.6 Personal history of allergy to analgesic agent
0.735 0.265 0.000
M54.9 Dorsalgia, unspecified
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.734 0.266 0.000
B35-B49 Mycoses
0.732 0.268 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.732 0.268 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.729 0.271 0.000
Z02 Examination and encounter for administrative purposes
0.729 0.271 0.000
S09 Other and unspecified injuries of head
0.728 0.272 0.000
Chapter VIII Diseases of the ear and mastoid process
0.727 0.273 0.000
M54.5 Low back pain
0.727 0.273 0.000
Z50.2 Alcohol rehabilitation
0.726 0.273 0.000
C44.3 Skin of other and unspecified parts of face
0.726 0.274 0.000
M31 Other necrotising vasculopathies
0.724 0.275 0.000
Z50.5 Speech therapy
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.724 0.276 0.000
S52.1 Fracture of upper end of radius
0.723 0.277 0.000
N63 Unspecified lump in breast
0.721 0.279 0.000
R32 Unspecified urinary incontinence
0.720 0.280 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.719 0.281 0.000
Z46.8 Fitting and adjustment of other specified devices
0.719 0.281 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z10 Routine general health check-up of defined subpopulation
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
Z12 Special screening examination for neoplasms
0.716 0.284 0.000
R30.9 Painful micturition, unspecified
0.715 0.285 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.715 0.285 0.000
A46 Erysipelas
0.714 0.286 0.000
S59 Other and unspecified injuries of forearm
0.714 0.286 0.000
S58 Traumatic amputation of forearm
0.714 0.286 0.000
S57 Crushing injury of forearm
0.714 0.286 0.000
S56 Injury of muscle and tendon at forearm level
0.714 0.286 0.000
S55 Injury of blood vessels at forearm level
0.714 0.286 0.000
S54 Injury of nerves at forearm level
0.714 0.286 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.714 0.286 0.000
S51 Open wound of forearm
0.714 0.286 0.000
S50 Superficial injury of forearm
0.714 0.286 0.000
Z75 Problems related to medical facilities and other health care
0.714 0.286 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.713 0.287 0.000
M35.0 Sicca syndrome [Sjogren]
0.713 0.287 0.000
Z52 Donors of organs and tissues
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
S52.9 Fracture of forearm, part unspecified
0.712 0.288 0.000
S52.8 Fracture of other parts of forearm
0.712 0.288 0.000
S52.7 Multiple fractures of forearm
0.712 0.288 0.000
S52.4 Fracture of shafts of both ulna and radius
0.712 0.288 0.000
S52.3 Fracture of shaft of radius
0.712 0.288 0.000
S52.2 Fracture of shaft of ulna
0.712 0.288 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.711 0.289 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.710 0.290 0.000
R47-R49 Symptoms and signs involving speech and voice
0.709 0.291 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.708 0.292 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.708 0.292 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.708 0.292 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.707 0.292 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
Z50.6 Orthoptic training
0.707 0.293 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.707 0.293 0.000
Z50.3 Drug rehabilitation
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.706 0.294 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.706 0.294 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.705 0.295 0.000
E84 Cystic fibrosis
0.705 0.295 0.000
E79 Disorders of purine and pyrimidine metabolism
0.705 0.295 0.000
E77 Disorders of glycoprotein metabolism
0.705 0.295 0.000
E76 Disorders of glycosaminoglycan metabolism
0.705 0.295 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.705 0.295 0.000
E74 Other disorders of carbohydrate metabolism
0.705 0.295 0.000
E73 Lactose intolerance
0.705 0.295 0.000
E72 Other disorders of amino-acid metabolism
0.705 0.295 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.705 0.295 0.000
E70 Disorders of aromatic amino-acid metabolism
0.705 0.295 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.705 0.295 0.000
M25.56 Pain in joint (Lower leg)
0.704 0.296 0.000
J18 Pneumonia, organism unspecified
0.704 0.296 0.000
W00-W19 Falls
0.701 0.299 0.000
Z96 Presence of other functional implants
0.701 0.299 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.699 0.301 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.699 0.301 0.000
N46 Male infertility
0.699 0.301 0.000
N44 Torsion of testis
0.699 0.301 0.000
Z04.1 Examination and observation following transport accident
0.699 0.301 0.000
K55-K64 Other diseases of intestines
0.699 0.301 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.698 0.302 0.000
T45.0 Antiallergic and antiemetic drugs
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
M43 Other deforming dorsopathies
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.697 0.303 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.697 0.303 0.000
M51 Other intervertebral disk disorders
0.696 0.304 0.000
R36 Urethral discharge
0.695 0.305 0.000
R34 Anuria and oliguria
0.695 0.305 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.695 0.305 0.000
R63.0 Anorexia
0.695 0.305 0.000
Z04.3 Examination and observation following other accident
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.305 0.000
M33 Dermatopolymyositis
0.695 0.305 0.000
M32 Systemic lupus erythematosus
0.695 0.305 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.305 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.694 0.305 0.000
M70-M79 Other soft tissue disorders
0.694 0.306 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.693 0.307 0.000
A49 Bacterial infection of unspecified site
0.693 0.307 0.000
J33 Nasal polyp
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.692 0.308 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
T36 Poisoning by systemic antibiotics
0.692 0.308 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.692 0.308 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.692 0.308 0.000
Z03.3 Observation for suspected nervous system disorder
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.309 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.691 0.309 0.000
B99-B99 Other infectious diseases
0.690 0.309 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.690 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.309 0.000
B65-B83 Helminthiases
0.690 0.309 0.000
B50-B64 Protozoal diseases
0.690 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.690 0.309 0.000
A75-A79 Rickettsioses
0.690 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.309 0.000
A65-A69 Other spirochaetal diseases
0.690 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.309 0.000
A15-A19 Tuberculosis
0.690 0.309 0.000
M10 Gout
0.691 0.309 0.000
A41.9 Septicaemia, unspecified
0.690 0.310 0.000
Z94.8 Other transplanted organ and tissue status
0.690 0.310 0.000
C44.4 Skin of scalp and neck
0.689 0.311 0.000
C71 Malignant neoplasm of brain
0.689 0.311 0.000
Z87.8 Personal history of other specified conditions
0.688 0.312 0.000
Z03.1 Observation for suspected malignant neoplasm
0.687 0.313 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.687 0.313 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.687 0.313 0.000
J32 Chronic sinusitis
0.686 0.314 0.000
R35 Polyuria
0.686 0.314 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.685 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.685 0.314 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.685 0.314 0.000
D27 Benign neoplasm of ovary
0.685 0.315 0.000
K58 Irritable bowel syndrome
0.685 0.315 0.000
N60 Benign mammary dysplasia
0.683 0.317 0.000
N61 Inflammatory disorders of breast
0.683 0.317 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.682 0.318 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.680 0.319 0.000
Z90.0 Acquired absence of part of head and neck
0.680 0.320 0.000
N13 Obstructive and reflux uropathy
0.680 0.320 0.000
S72 Fracture of femur
0.679 0.321 0.000
E89.2 Postprocedural hypoparathyroidism
0.679 0.321 0.000
W20-W49 Exposure to inanimate mechanical forces
0.678 0.322 0.000
Chapter VI Diseases of the nervous system
0.678 0.322 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.678 0.322 0.000
Z04.8 Examination and observation for other specified reasons
0.677 0.323 0.000
R54 Senility
0.677 0.323 0.000
T40.2 Other opioids
0.677 0.323 0.000
E16 Other disorders of pancreatic internal secretion
0.677 0.323 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.675 0.325 0.000
M35.8 Other specified systemic involvement of connective tissue
0.675 0.325 0.000
M35.7 Hypermobility syndrome
0.675 0.325 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.675 0.325 0.000
M35.5 Multifocal fibrosclerosis
0.675 0.325 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.675 0.325 0.000
M35.2 Behcet's disease
0.675 0.325 0.000
M35.1 Other overlap syndromes
0.675 0.325 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.675 0.325 0.000
E53 Deficiency of other B group vitamins
0.675 0.325 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.674 0.326 0.000
M24 Other specific joint derangements
0.673 0.327 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.673 0.327 0.000
R68 Other general symptoms and signs
0.673 0.327 0.000
M25.4 Effusion of joint
0.672 0.328 0.000
K70-K77 Diseases of liver
0.672 0.328 0.000
M46 Other inflammatory spondylopathies
0.672 0.328 0.000
Z28 Immunisation not carried out
0.671 0.329 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.671 0.329 0.000
Z26 Need for immunisation against other single infectious diseases
0.671 0.329 0.000
Z25 Need for immunisation against other single viral diseases
0.671 0.329 0.000
Z24 Need for immunisation against certain single viral diseases
0.671 0.329 0.000
Z23 Need for immunisation against single bacterial diseases
0.671 0.329 0.000
Z20 Contact with and exposure to communicable diseases
0.671 0.329 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.671 0.329 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
D17 Benign lipomatous neoplasm
0.670 0.330 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.669 0.331 0.000
E83.8 Other disorders of mineral metabolism
0.669 0.331 0.000
E83.3 Disorders of phosphorus metabolism
0.669 0.331 0.000
E83.2 Disorders of zinc metabolism
0.669 0.331 0.000
E83.0 Disorders of copper metabolism
0.669 0.331 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.668 0.332 0.000
C44.5 Skin of trunk
0.668 0.332 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.668 0.332 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.668 0.332 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.668 0.332 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.668 0.332 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.668 0.332 0.000
Z46.1 Fitting and adjustment of hearing aid
0.668 0.332 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.668 0.332 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.668 0.332 0.000
R39.2 Extrarenal uraemia
0.666 0.334 0.000
R39.0 Extravasation of urine
0.666 0.334 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.666 0.334 0.000
Z90.3 Acquired absence of part of stomach
0.665 0.335 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.665 0.335 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
S42 Fracture of shoulder and upper arm
0.665 0.335 0.000
M45 Ankylosing spondylitis
0.664 0.336 0.000
M48.09 Spinal stenosis (Site unspecified)
0.663 0.337 0.000
E87.5 Hyperkalaemia
0.662 0.338 0.000
R63.1 Polydipsia
0.662 0.338 0.000
Z93.0 Tracheostomy status
0.662 0.338 0.000
T87 Complications peculiar to reattachment and amputation
0.661 0.339 0.000
T86 Failure and rejection of transplanted organs and tissues
0.661 0.339 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.661 0.339 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.659 0.341 0.000
M49 Spondylopathies in diseases classified elsewhere
0.659 0.341 0.000
Z85.6 Personal history of leukaemia
0.658 0.341 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.658 0.342 0.000
Z22.5 Carrier of viral hepatitis
0.658 0.342 0.000
M53 Other dorsopathies, not elsewhere classified
0.658 0.342 0.000
N42.9 Disorder of prostate, unspecified
0.658 0.342 0.000
M05 Seropositive rheumatoid arthritis
0.658 0.342 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.657 0.343 0.000
E87.7 Fluid overload
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
S08 Traumatic amputation of part of head
0.657 0.343 0.000
S07 Crushing injury of head
0.657 0.343 0.000
S05 Injury of eye and orbit
0.657 0.343 0.000
S04 Injury of cranial nerves
0.657 0.343 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.657 0.343 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.657 0.343 0.000
N15 Other renal tubulo-interstitial diseases
0.657 0.343 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.657 0.343 0.000
N11 Chronic tubulo-interstitial nephritis
0.657 0.343 0.000
N10 Acute tubulo-interstitial nephritis
0.657 0.343 0.000
N45 Orchitis and epididymitis
0.656 0.344 0.000
R57 Shock, not elsewhere classified
0.656 0.344 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.656 0.344 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.656 0.344 0.000
C56 Malignant neoplasm of ovary
0.655 0.345 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.655 0.345 0.000
M13 Other arthritis
0.655 0.345 0.000
M22 Disorders of patella
0.655 0.345 0.000
S70 Superficial injury of hip and thigh
0.655 0.345 0.000
C50.3 Lower-inner quadrant of breast
0.654 0.346 0.000
K65-K67 Diseases of peritoneum
0.654 0.346 0.000
Z74.0 Reduced mobility
0.654 0.346 0.000
S00.8 Superficial injury of other parts of head
0.653 0.347 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.652 0.348 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.651 0.349 0.000
R60.0 Localised oedema
0.651 0.349 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.650 0.350 0.000
R60.9 Oedema, unspecified
0.650 0.350 0.000
E55 Vitamin D deficiency
0.650 0.350 0.000
C67.6 Ureteric orifice
0.649 0.351 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.649 0.351 0.000
Z93.2 Ileostomy status
0.648 0.352 0.000
K50.0 Crohn's disease of small intestine
0.648 0.352 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.647 0.353 0.000
A48 Other bacterial diseases, not elsewhere classified
0.646 0.353 0.000
A44 Bartonellosis
0.646 0.353 0.000
A43 Nocardiosis
0.646 0.353 0.000
A42 Actinomycosis
0.646 0.353 0.000
A40 Streptococcal septicaemia
0.646 0.353 0.000
A39 Meningococcal infection
0.646 0.353 0.000
A37 Whooping cough
0.646 0.353 0.000
A36 Diphtheria
0.646 0.353 0.000
A32 Listeriosis
0.646 0.353 0.000
A31 Infection due to other mycobacteria
0.646 0.353 0.000
A30 Leprosy [Hansen's disease]
0.646 0.353 0.000
A38 Scarlet fever
0.646 0.353 0.000
A35 Other tetanus
0.646 0.353 0.000
A34 Obstetrical tetanus
0.646 0.353 0.000
A33 Tetanus neonatorum
0.646 0.353 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.646 0.354 0.000
E85.4 Organ-limited amyloidosis
0.646 0.354 0.000
N18 Chronic renal failure
0.644 0.356 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.644 0.356 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
B34 Viral infection of unspecified site
0.643 0.357 0.000
S01.0 Open wound of scalp
0.643 0.357 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.643 0.357 0.000
S01.7 Multiple open wounds of head
0.643 0.357 0.000
Z40 Prophylactic surgery
0.642 0.358 0.000
Z48 Other surgical follow-up care
0.642 0.358 0.000
Z03.8 Observation for other suspected diseases and conditions
0.642 0.358 0.000
M54.59 Low back pain (Site unspecified)
0.642 0.358 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.641 0.359 0.000
M25.9 Joint disorder, unspecified
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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