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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7459527
log Bayes Factor = 0.0670646
Chromosome 8   position 118,909,260  (GRCh37) Explore rs7459527 on Ensembl!
Variant rs7459527 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.136 0.864 0.000
# Top node
0.133 0.867 0.000
Chapter II Neoplasms
0.133 0.867 0.000
R50-R69 General symptoms and signs
0.131 0.869 0.000
Chapter X Diseases of the respiratory system
0.130 0.870 0.000
Chapter VI Diseases of the nervous system
0.125 0.875 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.125 0.875 0.000
D10-D36 Benign neoplasms
0.122 0.878 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.121 0.879 0.000
J30-J39 Other diseases of upper respiratory tract
0.121 0.879 0.000
Chapter I Certain infectious and parasitic diseases
0.117 0.883 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.116 0.884 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.115 0.885 0.000
R63 Symptoms and signs concerning food and fluid intake
0.113 0.887 0.000
R13 Dysphagia
0.112 0.888 0.000
R51 Headache
0.112 0.888 0.000
R00 Abnormalities of heart beat
0.112 0.888 0.000
R55 Syncope and collapse
0.111 0.889 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.109 0.891 0.000
C15-C26 Malignant neoplasms of digestive organs
0.108 0.892 0.000
R07 Pain in throat and chest
0.108 0.892 0.000
J90-J94 Other diseases of pleura
0.107 0.893 0.000
G40-G47 Episodic and paroxysmal disorders
0.107 0.893 0.000
J09-J18 Influenza and pneumonia
0.107 0.893 0.000
Chapter V Mental and behavioural disorders
0.106 0.893 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.106 0.894 0.000
C51-C58 Malignant neoplasms of female genital organs
0.106 0.894 0.000
J00-J06 Acute upper respiratory infections
0.105 0.895 0.000
R50 Fever of unknown origin
0.105 0.895 0.000
C64-C68 Malignant neoplasms of urinary tract
0.105 0.895 0.000
J34 Other disorders of nose and nasal sinuses
0.105 0.895 0.000
D00-D09 In situ neoplasms
0.104 0.896 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.104 0.896 0.000
C50-C50 Malignant neoplasm of breast
0.103 0.896 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.103 0.897 0.000
D25 Leiomyoma of uterus
0.103 0.897 0.000
A30-A49 Other bacterial diseases
0.103 0.897 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.103 0.897 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.102 0.898 0.000
R04 Haemorrhage from respiratory passages
0.102 0.898 0.000
R47-R49 Symptoms and signs involving speech and voice
0.101 0.898 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.100 0.900 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.100 0.900 0.000
G20-G26 Extrapyramidal and movement disorders
0.100 0.900 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.100 0.900 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.100 0.900 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.099 0.900 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.098 0.902 0.000
J95-J99 Other diseases of the respiratory system
0.098 0.902 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.098 0.902 0.000
J33 Nasal polyp
0.098 0.902 0.000
C60-C63 Malignant neoplasms of male genital organs
0.098 0.902 0.000
R63.4 Abnormal weight loss
0.098 0.902 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.097 0.903 0.000
D18 Haemangioma and lymphangioma, any site
0.097 0.903 0.000
R60 Oedema, not elsewhere classified
0.097 0.903 0.000
R57 Shock, not elsewhere classified
0.096 0.904 0.000
R61 Hyperhidrosis
0.096 0.904 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.096 0.904 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.096 0.904 0.000
J20-J22 Other acute lower respiratory infections
0.096 0.904 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.096 0.904 0.000
R02 Gangrene, not elsewhere classified
0.095 0.904 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.095 0.904 0.000
R54 Senility
0.095 0.905 0.000
R58 Haemorrhage, not elsewhere classified
0.095 0.905 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.095 0.905 0.000
D25.9 Leiomyoma of uterus, unspecified
0.095 0.905 0.000
B95-B98 Bacterial, viral and other infectious agents
0.095 0.905 0.000
R59 Enlarged lymph nodes
0.095 0.905 0.000
L60-L75 Disorders of skin appendages
0.095 0.905 0.000
R00.2 Palpitations
0.095 0.905 0.000
R64 Cachexia
0.095 0.905 0.000
G47 Sleep disorders
0.095 0.905 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.095 0.905 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.095 0.905 0.000
R68 Other general symptoms and signs
0.094 0.905 0.000
R62 Lack of expected normal physiological development
0.094 0.906 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.094 0.906 0.000
J60-J70 Lung diseases due to external agents
0.094 0.906 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.094 0.906 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.094 0.906 0.000
R00.1 Bradycardia, unspecified
0.094 0.906 0.000
R56 Convulsions, not elsewhere classified
0.093 0.907 0.000
R21 Rash and other nonspecific skin eruption
0.093 0.907 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.093 0.907 0.000
D36 Benign neoplasm of other and unspecified sites
0.093 0.907 0.000
S00-S09 Injuries to the head
0.093 0.907 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.093 0.907 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.093 0.907 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.092 0.907 0.000
Chapter XXII Codes for special purposes
0.092 0.907 0.000
R17 Unspecified jaundice
0.092 0.907 0.000
R18 Ascites
0.092 0.908 0.000
J39 Other diseases of upper respiratory tract
0.092 0.908 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.092 0.908 0.000
R15 Faecal incontinence
0.092 0.908 0.000
D24 Benign neoplasm of breast
0.092 0.908 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.091 0.909 0.000
J36 Peritonsillar abscess
0.091 0.909 0.000
R06 Abnormalities of breathing
0.091 0.909 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.091 0.909 0.000
J32 Chronic sinusitis
0.091 0.909 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.091 0.909 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.091 0.909 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.091 0.909 0.000
J34.2 Deviated nasal septum
0.090 0.909 0.000
D34 Benign neoplasm of thyroid gland
0.090 0.910 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.090 0.910 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.090 0.910 0.000
A41 Other septicaemia
0.090 0.910 0.000
D26 Other benign neoplasms of uterus
0.090 0.910 0.000
G90-G99 Other disorders of the nervous system
0.090 0.910 0.000
R52 Pain, not elsewhere classified
0.090 0.910 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.089 0.910 0.000
G70-G73 Diseases of myoneural junction and muscle
0.089 0.910 0.000
D12.6 Colon, unspecified
0.089 0.911 0.000
S60-S69 Injuries to the wrist and hand
0.089 0.911 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.089 0.911 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.089 0.911 0.000
R69 Unknown and unspecified causes of morbidity
0.089 0.911 0.000
D30 Benign neoplasm of urinary organs
0.089 0.911 0.000
D29 Benign neoplasm of male genital organs
0.089 0.911 0.000
D27 Benign neoplasm of ovary
0.089 0.911 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.088 0.912 0.000
D12.5 Sigmoid colon
0.088 0.912 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.088 0.912 0.000
J37 Chronic laryngitis and laryngotracheitis
0.088 0.912 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.088 0.912 0.000
D19 Benign neoplasm of mesothelial tissue
0.087 0.912 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.087 0.913 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.087 0.913 0.000
J18 Pneumonia, organism unspecified
0.087 0.913 0.000
R07.4 Chest pain, unspecified
0.087 0.913 0.000
D32 Benign neoplasm of meninges
0.087 0.913 0.000
G30-G32 Other degenerative diseases of the nervous system
0.087 0.913 0.000
D10 Benign neoplasm of mouth and pharynx
0.086 0.914 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.086 0.914 0.000
R63.0 Anorexia
0.086 0.914 0.000
R20 Disturbances of skin sensation
0.086 0.914 0.000
L40-L45 Papulosquamous disorders
0.086 0.914 0.000
D23 Other benign neoplasms of skin
0.086 0.914 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.086 0.914 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.086 0.914 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.086 0.914 0.000
R23 Other skin changes
0.085 0.914 0.000
R50.9 Fever, unspecified
0.085 0.914 0.000
A80-A89 Viral infections of the central nervous system
0.085 0.915 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.085 0.915 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.085 0.915 0.000
J30 Vasomotor and allergic rhinitis
0.085 0.915 0.000
J90 Pleural effusion, not elsewhere classified
0.085 0.915 0.000
R07.2 Precordial pain
0.085 0.915 0.000
B65-B83 Helminthiases
0.085 0.915 0.000
R00.0 Tachycardia, unspecified
0.085 0.915 0.000
B50-B64 Protozoal diseases
0.085 0.915 0.000
B99-B99 Other infectious diseases
0.085 0.915 0.000
C18 Malignant neoplasm of colon
0.085 0.915 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.084 0.916 0.000
A65-A69 Other spirochaetal diseases
0.084 0.916 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.084 0.916 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.084 0.916 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.084 0.916 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.084 0.916 0.000
A75-A79 Rickettsioses
0.084 0.916 0.000
A70-A74 Other diseases caused by chlamydiae
0.084 0.916 0.000
G47.3 Sleep apnoea
0.084 0.916 0.000
D11 Benign neoplasm of major salivary glands
0.084 0.916 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.084 0.916 0.000
R53 Malaise and fatigue
0.084 0.916 0.000
B25-B34 Other viral diseases
0.084 0.916 0.000
R12 Heartburn
0.084 0.916 0.000
D31 Benign neoplasm of eye and adnexa
0.083 0.916 0.000
B15-B19 Viral hepatitis
0.083 0.916 0.000
L20-L30 Dermatitis and eczema
0.083 0.917 0.000
L10-L14 Bullous disorders
0.083 0.917 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.083 0.917 0.000
B35-B49 Mycoses
0.083 0.917 0.000
D05 Carcinoma in situ of breast
0.083 0.917 0.000
A15-A19 Tuberculosis
0.083 0.917 0.000
R07.3 Other chest pain
0.083 0.917 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.082 0.917 0.000
R01 Cardiac murmurs and other cardiac sounds
0.082 0.917 0.000
C15 Malignant neoplasm of oesophagus
0.082 0.917 0.000
J35 Chronic diseases of tonsils and adenoids
0.082 0.917 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.082 0.917 0.000
C50 Malignant neoplasm of breast
0.082 0.917 0.000
A20-A28 Certain zoonotic bacterial diseases
0.082 0.918 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.082 0.918 0.000
C16 Malignant neoplasm of stomach
0.082 0.918 0.000
S20-S29 Injuries to the thorax
0.082 0.918 0.000
D16 Benign neoplasm of bone and articular cartilage
0.082 0.918 0.000
J92 Pleural plaque
0.082 0.918 0.000
R63.5 Abnormal weight gain
0.082 0.918 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.082 0.918 0.000
C54 Malignant neoplasm of corpus uteri
0.082 0.918 0.000
R63.3 Feeding difficulties and mismanagement
0.082 0.918 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.082 0.918 0.000
S70-S79 Injuries to the hip and thigh
0.082 0.918 0.000
R63.2 Polyphagia
0.081 0.918 0.000
Chapter XX External causes of morbidity and mortality
0.081 0.919 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.081 0.919 0.000
C67 Malignant neoplasm of bladder
0.081 0.919 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.081 0.919 0.000
D18.0 Haemangioma, any site
0.081 0.919 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.081 0.919 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.081 0.919 0.000
S50-S59 Injuries to the elbow and forearm
0.081 0.919 0.000
R07.0 Pain in throat
0.081 0.919 0.000
S90-S99 Injuries to the ankle and foot
0.081 0.919 0.000
C25 Malignant neoplasm of pancreas
0.081 0.919 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.081 0.919 0.000
R04.2 Haemoptysis
0.081 0.919 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.081 0.919 0.000
G20 Parkinson's disease
0.080 0.920 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.080 0.920 0.000
S10-S19 Injuries to the neck
0.080 0.920 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.080 0.920 0.000
C92 Myeloid leukaemia
0.080 0.920 0.000
R14 Flatulence and related conditions
0.080 0.920 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.080 0.920 0.000
D12.0 Caecum
0.080 0.920 0.000
G35 Multiple sclerosis
0.080 0.920 0.000
R63.1 Polydipsia
0.079 0.921 0.000
J03 Acute tonsillitis
0.079 0.921 0.000
L50-L54 Urticaria and erythema
0.079 0.921 0.000
J33.9 Nasal polyp, unspecified
0.079 0.921 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.079 0.921 0.000
J00 Acute nasopharyngitis [common cold]
0.079 0.921 0.000
J91 Pleural effusion in conditions classified elsewhere
0.079 0.921 0.000
J02 Acute pharyngitis
0.079 0.921 0.000
T00-T07 Injuries involving multiple body regions
0.079 0.921 0.000
J93 Pneumothorax
0.079 0.921 0.000
F60-F69 Disorders of adult personality and behaviour
0.079 0.921 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.079 0.921 0.000
T66-T78 Other and unspecified effects of external causes
0.079 0.921 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.079 0.921 0.000
T79-T79 Certain early complications of trauma
0.079 0.921 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.078 0.921 0.000
C20 Malignant neoplasm of rectum
0.078 0.921 0.000
Chapter VIII Diseases of the ear and mastoid process
0.078 0.921 0.000
R04.0 Epistaxis
0.078 0.921 0.000
C23 Malignant neoplasm of gallbladder
0.078 0.921 0.000
A41.9 Septicaemia, unspecified
0.078 0.922 0.000
C56 Malignant neoplasm of ovary
0.078 0.922 0.000
R10 Abdominal and pelvic pain
0.078 0.922 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.078 0.922 0.000
G44 Other headache syndromes
0.078 0.922 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.078 0.922 0.000
T33-T35 Frostbite
0.078 0.922 0.000
F80-F89 Disorders of psychological development
0.078 0.922 0.000
R19.4 Change in bowel habit
0.078 0.922 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.078 0.922 0.000
J10 Influenza due to identified influenza virus
0.078 0.922 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.078 0.922 0.000
G41 Status epilepticus
0.078 0.922 0.000
C53 Malignant neoplasm of cervix uteri
0.078 0.922 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.078 0.922 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.078 0.922 0.000
J17 Pneumonia in diseases classified elsewhere
0.078 0.922 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.078 0.922 0.000
J14 Pneumonia due to Haemophilus influenzae
0.078 0.922 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.078 0.922 0.000
G81 Hemiplegia
0.077 0.922 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.077 0.923 0.000
R25 Abnormal involuntary movements
0.077 0.923 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.077 0.923 0.000
Chapter IX Diseases of the circulatory system
0.077 0.923 0.000
J12 Viral pneumonia, not elsewhere classified
0.077 0.923 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.077 0.923 0.000
C88 Malignant immunoproliferative diseases
0.077 0.923 0.000
D22 Melanocytic naevi
0.077 0.923 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.077 0.923 0.000
J09 Influenza due to certain identified influenza virus
0.077 0.923 0.000
J01 Acute sinusitis
0.077 0.923 0.000
R80 Isolated proteinuria
0.077 0.923 0.000
C95 Leukaemia of unspecified cell type
0.077 0.923 0.000
C51 Malignant neoplasm of vulva
0.077 0.923 0.000
R50.8 Other specified fever
0.077 0.923 0.000
F70-F79 Mental retardation
0.077 0.923 0.000
J04 Acute laryngitis and tracheitis
0.077 0.923 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.077 0.923 0.000
C93 Monocytic leukaemia
0.077 0.923 0.000
J94 Other pleural conditions
0.077 0.923 0.000
C94 Other leukaemias of specified cell type
0.077 0.923 0.000
C86 Other specified types of T/NK-cell lymphoma
0.077 0.923 0.000
D06 Carcinoma in situ of cervix uteri
0.077 0.923 0.000
J33.0 Polyp of nasal cavity
0.077 0.923 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.076 0.923 0.000
A49 Bacterial infection of unspecified site
0.076 0.923 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.076 0.923 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.076 0.923 0.000
R82 Other abnormal findings in urine
0.076 0.923 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.076 0.923 0.000
C52 Malignant neoplasm of vagina
0.076 0.923 0.000
L03 Cellulitis
0.076 0.923 0.000
R07.1 Chest pain on breathing
0.076 0.924 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.076 0.924 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.076 0.924 0.000
R47 Speech disturbances, not elsewhere classified
0.076 0.924 0.000
R87 Abnormal findings in specimens from female genital organs
0.076 0.924 0.000
C58 Malignant neoplasm of placenta
0.076 0.924 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.076 0.924 0.000
C66 Malignant neoplasm of ureter
0.076 0.924 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.076 0.924 0.000
G43 Migraine
0.076 0.924 0.000
J34.3 Hypertrophy of nasal turbinates
0.076 0.924 0.000
R50.1 Persistent fever
0.076 0.924 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.076 0.924 0.000
R50.2 Drug-induced fever
0.076 0.924 0.000
J11 Influenza, virus not identified
0.076 0.924 0.000
F99-F99 Unspecified mental disorder
0.076 0.924 0.000
A40 Streptococcal septicaemia
0.075 0.924 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.075 0.924 0.000
C43 Malignant melanoma of skin
0.075 0.924 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.075 0.924 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.075 0.924 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.075 0.925 0.000
G40 Epilepsy
0.075 0.925 0.000
R81 Glycosuria
0.075 0.925 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.075 0.925 0.000
R50.0 Fever with chills
0.075 0.925 0.000
A46 Erysipelas
0.075 0.925 0.000
D12.1 Appendix
0.075 0.925 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.075 0.925 0.000
C17 Malignant neoplasm of small intestine
0.074 0.925 0.000
R86 Abnormal findings in specimens from male genital organs
0.074 0.925 0.000
A48 Other bacterial diseases, not elsewhere classified
0.074 0.925 0.000
S00 Superficial injury of head
0.074 0.925 0.000
R79 Other abnormal findings of blood chemistry
0.074 0.926 0.000
D09 Carcinoma in situ of other and unspecified sites
0.074 0.926 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.074 0.926 0.000
A39 Meningococcal infection
0.074 0.926 0.000
J18.1 Lobar pneumonia, unspecified
0.074 0.926 0.000
A31 Infection due to other mycobacteria
0.074 0.926 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.074 0.926 0.000
R27 Other lack of coordination
0.074 0.926 0.000
D12.3 Transverse colon
0.074 0.926 0.000
C44 Other malignant neoplasms of skin
0.074 0.926 0.000
J40-J47 Chronic lower respiratory diseases
0.074 0.926 0.000
A42 Actinomycosis
0.074 0.926 0.000
C81 Hodgkin's disease
0.074 0.926 0.000
J98 Other respiratory disorders
0.074 0.926 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.074 0.926 0.000
A44 Bartonellosis
0.074 0.926 0.000
A43 Nocardiosis
0.074 0.926 0.000
A37 Whooping cough
0.074 0.926 0.000
A36 Diphtheria
0.074 0.926 0.000
A32 Listeriosis
0.074 0.926 0.000
A30 Leprosy [Hansen's disease]
0.074 0.926 0.000
A38 Scarlet fever
0.074 0.926 0.000
A35 Other tetanus
0.074 0.926 0.000
A34 Obstetrical tetanus
0.074 0.926 0.000
A33 Tetanus neonatorum
0.074 0.926 0.000
D46 Myelodysplastic syndromes
0.074 0.926 0.000
R83 Abnormal findings in cerebrospinal fluid
0.073 0.926 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.073 0.926 0.000
G24 Dystonia
0.073 0.926 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.073 0.926 0.000
C09 Malignant neoplasm of tonsil
0.073 0.926 0.000
D03 Melanoma in situ
0.073 0.926 0.000
D25.1 Intramural leiomyoma of uterus
0.073 0.926 0.000
G37 Other demyelinating diseases of central nervous system
0.073 0.927 0.000
C01 Malignant neoplasm of base of tongue
0.073 0.927 0.000
R04.1 Haemorrhage from throat
0.073 0.927 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.073 0.927 0.000
G62 Other polyneuropathies
0.073 0.927 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.073 0.927 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.073 0.927 0.000
R76 Other abnormal immunological findings in serum
0.073 0.927 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.073 0.927 0.000
R74 Abnormal serum enzyme levels
0.073 0.927 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.073 0.927 0.000
D04 Carcinoma in situ of skin
0.073 0.927 0.000
R49 Voice disturbances
0.073 0.927 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.073 0.927 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.073 0.927 0.000
G82 Paraplegia and tetraplegia
0.073 0.927 0.000
C07 Malignant neoplasm of parotid gland
0.073 0.927 0.000
C65 Malignant neoplasm of renal pelvis
0.073 0.927 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.073 0.927 0.000
C61 Malignant neoplasm of prostate
0.073 0.927 0.000
C05 Malignant neoplasm of palate
0.072 0.927 0.000
S80-S89 Injuries to the knee and lower leg
0.072 0.927 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.072 0.927 0.000
C10 Malignant neoplasm of oropharynx
0.072 0.927 0.000
C21 Malignant neoplasm of anus and anal canal
0.072 0.927 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.072 0.927 0.000
C00 Malignant neoplasm of lip
0.072 0.927 0.000
C12 Malignant neoplasm of pyriform sinus
0.072 0.927 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.072 0.928 0.000
C11 Malignant neoplasm of nasopharynx
0.072 0.928 0.000
C03 Malignant neoplasm of gum
0.072 0.928 0.000
D12.9 Anus and anal canal
0.072 0.928 0.000
C13 Malignant neoplasm of hypopharynx
0.072 0.928 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.072 0.928 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.072 0.928 0.000
R05 Cough
0.072 0.928 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.072 0.928 0.000
C62 Malignant neoplasm of testis
0.072 0.928 0.000
R71 Abnormality of red blood cells
0.072 0.928 0.000
G47.9 Sleep disorder, unspecified
0.072 0.928 0.000
G21 Secondary Parkinsonism
0.072 0.928 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.072 0.928 0.000
G23 Other degenerative diseases of basal ganglia
0.072 0.928 0.000
C91 Lymphoid leukaemia
0.072 0.928 0.000
D17 Benign lipomatous neoplasm
0.072 0.928 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.072 0.928 0.000
G22 Parkinsonism in diseases classified elsewhere
0.072 0.928 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.072 0.928 0.000
S02 Fracture of skull and facial bones
0.072 0.928 0.000
G61 Inflammatory polyneuropathy
0.072 0.928 0.000
D12.7 Rectosigmoid junction
0.072 0.928 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.072 0.928 0.000
G80 Infantile cerebral palsy
0.072 0.928 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.072 0.928 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.072 0.928 0.000
G36 Other acute disseminated demyelination
0.071 0.928 0.000
G25 Other extrapyramidal and movement disorders
0.071 0.928 0.000
F30-F39 Mood [affective] disorders
0.072 0.928 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.071 0.928 0.000
A00-A09 Intestinal infectious diseases
0.071 0.929 0.000
S61 Open wound of wrist and hand
0.071 0.929 0.000
J69 Pneumonitis due to solids and liquids
0.071 0.929 0.000
S01 Open wound of head
0.071 0.929 0.000
D12.2 Ascending colon
0.071 0.929 0.000
C45 Mesothelioma
0.071 0.929 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.071 0.929 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.071 0.929 0.000
R60.0 Localised oedema
0.071 0.929 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.071 0.929 0.000
R61.9 Hyperhidrosis, unspecified
0.071 0.929 0.000
D25.2 Subserosal leiomyoma of uterus
0.071 0.929 0.000
J86 Pyothorax
0.071 0.929 0.000
G60 Hereditary and idiopathic neuropathy
0.071 0.929 0.000
R06.0 Dyspnoea
0.071 0.929 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.071 0.929 0.000
J33.1 Polypoid sinus degeneration
0.071 0.929 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.070 0.929 0.000
R99 Other ill-defined and unspecified causes of mortality
0.070 0.929 0.000
J96 Respiratory failure, not elsewhere classified
0.070 0.929 0.000
J22 Unspecified acute lower respiratory infection
0.071 0.929 0.000
R96 Other sudden death, cause unknown
0.070 0.929 0.000
R95 Sudden infant death syndrome
0.070 0.929 0.000
R98 Unattended death
0.070 0.929 0.000
S40-S49 Injuries to the shoulder and upper arm
0.070 0.929 0.000
C04 Malignant neoplasm of floor of mouth
0.070 0.929 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.070 0.929 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.070 0.929 0.000
R57.2 Septic shock
0.070 0.929 0.000
R77 Other abnormalities of plasma proteins
0.070 0.930 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.070 0.930 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.070 0.930 0.000
J32.9 Chronic sinusitis, unspecified
0.070 0.930 0.000
G64 Other disorders of peripheral nervous system
0.070 0.930 0.000
R60.1 Generalised oedema
0.070 0.930 0.000
R57.0 Cardiogenic shock
0.070 0.930 0.000
J20 Acute bronchitis
0.070 0.930 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.070 0.930 0.000
J39.2 Other diseases of pharynx
0.070 0.930 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.070 0.930 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.070 0.930 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.070 0.930 0.000
R06.8 Other and unspecified abnormalities of breathing
0.070 0.930 0.000
R60.9 Oedema, unspecified
0.070 0.930 0.000
R73 Elevated blood glucose level
0.070 0.930 0.000
L08 Other local infections of skin and subcutaneous tissue
0.070 0.930 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.070 0.930 0.000
S06 Intracranial injury
0.070 0.930 0.000
R61.0 Localised hyperhidrosis
0.069 0.930 0.000
R57.9 Shock, unspecified
0.069 0.930 0.000
R59.1 Generalised enlarged lymph nodes
0.069 0.930 0.000
R57.1 Hypovolaemic shock
0.069 0.930 0.000
J85 Abscess of lung and mediastinum
0.069 0.930 0.000
J21 Acute bronchiolitis
0.069 0.931 0.000
R61.1 Generalised hyperhidrosis
0.069 0.931 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.069 0.931 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.069 0.931 0.000
R57.8 Other shock
0.069 0.931 0.000
R11 Nausea and vomiting
0.069 0.931 0.000
C46 Kaposi's sarcoma
0.069 0.931 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.069 0.931 0.000
L72.0 Epidermal cyst
0.069 0.931 0.000
D80-D89 Certain disorders involving the immune mechanism
0.069 0.931 0.000
J38.7 Other diseases of larynx
0.069 0.931 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.069 0.931 0.000
D45 Polycythaemia vera
0.069 0.931 0.000
R16.1 Splenomegaly, not elsewhere classified
0.069 0.931 0.000
S05 Injury of eye and orbit
0.069 0.931 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.069 0.931 0.000
C71 Malignant neoplasm of brain
0.069 0.931 0.000
J80 Adult respiratory distress syndrome
0.069 0.931 0.000
C60 Malignant neoplasm of penis
0.069 0.931 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.069 0.931 0.000
G83 Other paralytic syndromes
0.069 0.931 0.000
P10-P15 Birth trauma
0.069 0.931 0.000
L73 Other follicular disorders
0.069 0.931 0.000
G47.8 Other sleep disorders
0.069 0.931 0.000
P90-P96 Other disorders originating in the perinatal period
0.069 0.931 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.069 0.931 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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