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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28493987
log Bayes Factor = 0.00029576
Chromosome 8   position 75,341,097  (GRCh37) Explore rs28493987 on Ensembl!
Variant rs28493987 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.000 0.999 0.001
Chapter XXI Factors influencing health status and contact with health services
0.000 0.999 0.001
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.000 0.999 0.001
Z00-Z13 Persons encountering health services for examination and investigation
0.000 0.999 0.001
Chapter XX External causes of morbidity and mortality
0.000 0.999 0.001
Chapter XIV Diseases of the genitourinary system
0.000 0.999 0.001
Chapter VII Diseases of the eye and adnexa
0.000 0.999 0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.999 0.001
Chapter VIII Diseases of the ear and mastoid process
0.000 0.999 0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.999 0.001
Chapter II Neoplasms
0.000 0.999 0.001
Z87 Personal history of other diseases and conditions
0.000 0.999 0.001
Z40-Z54 Persons encountering health services for specific procedures and health care
0.000 0.999 0.001
Chapter XXII Codes for special purposes
0.000 0.999 0.001
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.999 0.001
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.999 0.001
Chapter XV Pregnancy, childbirth and the puerperium
0.000 0.999 0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.000 0.999 0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.999 0.001
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.999 0.001
Chapter X Diseases of the respiratory system
0.000 0.999 0.001
Chapter IX Diseases of the circulatory system
0.000 0.999 0.001
Chapter I Certain infectious and parasitic diseases
0.000 0.999 0.001
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.000 0.999 0.001
Z08 Follow-up examination after treatment for malignant neoplasm
0.000 0.999 0.001
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.999 0.001
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.000 0.999 0.001
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.000 0.999 0.001
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.000 0.999 0.001
Chapter VI Diseases of the nervous system
0.000 0.999 0.001
Chapter V Mental and behavioural disorders
0.000 0.999 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.999 0.001
Z87.4 Personal history of diseases of the genito-urinary system
0.000 0.999 0.001
Z86 Personal history of certain other diseases
0.000 0.999 0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.000 0.999 0.001
Chapter XI Diseases of the digestive system
0.000 0.999 0.001
Z51 Other medical care
0.000 0.999 0.001
Z85 Personal history of malignant neoplasm
0.000 0.999 0.001
H53-H54 Visual disturbances and blindness
0.000 0.999 0.001
H90-H95 Other disorders of ear
0.000 0.999 0.001
N99-N99 Other disorders of the genitourinary system
0.000 0.999 0.001
N80-N98 Noninflammatory disorders of female genital tract
0.000 0.999 0.001
Z87.1 Personal history of diseases of the digestive system
0.000 0.999 0.001
Z13 Special screening examination for other diseases and disorders
0.000 0.999 0.001
Z12 Special screening examination for neoplasms
0.000 0.999 0.001
Z11 Special screening examination for infectious and parasitic diseases
0.000 0.999 0.001
Z10 Routine general health check-up of defined subpopulation
0.000 0.999 0.001
Z04 Examination and observation for other reasons
0.000 0.999 0.001
Z03 Medical observation and evaluation for suspected diseases and conditions
0.000 0.999 0.001
Z02 Examination and encounter for administrative purposes
0.000 0.999 0.001
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.000 0.999 0.001
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.000 0.999 0.001
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.999 0.001
Z98 Other postsurgical states
0.000 0.999 0.001
Z97 Presence of other devices
0.000 0.999 0.001
Z96 Presence of other functional implants
0.000 0.999 0.001
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.999 0.001
Z94 Transplanted organ and tissue status
0.000 0.999 0.001
Z93 Artificial opening status
0.000 0.999 0.001
Z92 Personal history of medical treatment
0.000 0.999 0.001
Z91 Personal history of risk-factors, not elsewhere classified
0.000 0.999 0.001
Z90 Acquired absence of organs, not elsewhere classified
0.000 0.999 0.001
Z89 Acquired absence of limb
0.000 0.999 0.001
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.000 0.999 0.001
Z84 Family history of other conditions
0.000 0.999 0.001
Z83 Family history of other specific disorders
0.000 0.999 0.001
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.999 0.001
Z81 Family history of mental and behavioural disorders
0.000 0.999 0.001
Z80 Family history of malignant neoplasm
0.000 0.999 0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.999 0.001
C64-C68 Malignant neoplasms of urinary tract
0.000 0.999 0.001
C60-C63 Malignant neoplasms of male genital organs
0.000 0.999 0.001
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.999 0.001
H25-H28 Disorders of lens
0.000 0.999 0.001
N70-N77 Inflammatory diseases of female pelvic organs
0.000 0.999 0.001
N60-N64 Disorders of breast
0.000 0.999 0.001
N30-N39 Other diseases of urinary system
0.000 0.999 0.001
N25-N29 Other disorders of kidney and ureter
0.000 0.999 0.001
N20-N23 Urolithiasis
0.000 0.999 0.001
N17-N19 Renal failure
0.000 0.999 0.001
N10-N16 Renal tubulo-interstitial diseases
0.000 0.999 0.001
N00-N08 Glomerular diseases
0.000 0.999 0.001
R50-R69 General symptoms and signs
0.000 0.999 0.001
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.000 0.999 0.001
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.000 0.999 0.001
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.000 0.999 0.001
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.000 0.999 0.001
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.000 0.999 0.001
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.000 0.999 0.001
Y60-Y69 Misadventures to patients during surgical and medical care
0.000 0.999 0.001
Y35-Y36 Legal intervention and operations of war
0.000 0.999 0.001
Y10-Y34 Event of undetermined intent
0.000 0.999 0.001
Y00-Y09 Assault
0.000 0.999 0.001
X85-X99 Assault
0.000 0.999 0.001
X60-X84 Intentional self-harm
0.000 0.999 0.001
X58-X59 Accidental exposure to other and unspecified factors
0.000 0.999 0.001
X50-X57 Overexertion, travel and privation
0.000 0.999 0.001
X40-X49 Accidental poisoning by and exposure to noxious substances
0.000 0.999 0.001
X30-X39 Exposure to forces of nature
0.000 0.999 0.001
X20-X29 Contact with venomous animals and plants
0.000 0.999 0.001
X10-X19 Contact with heat and hot substances
0.000 0.999 0.001
X00-X09 Exposure to smoke, fire and flames
0.000 0.999 0.001
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.000 0.999 0.001
W75-W84 Other accidental threats to breathing
0.000 0.999 0.001
W65-W74 Accidental drowning and submersion
0.000 0.999 0.001
W50-W64 Exposure to animate mechanical forces
0.000 0.999 0.001
W20-W49 Exposure to inanimate mechanical forces
0.000 0.999 0.001
W00-W19 Falls
0.000 0.999 0.001
V98-V99 Other and unspecified transport accidents
0.000 0.999 0.001
V95-V97 Air and space transport accidents
0.000 0.999 0.001
V90-V94 Water transport accidents
0.000 0.999 0.001
V80-V89 Other land transport accidents
0.000 0.999 0.001
V70-V79 Bus occupant injured in transport accident
0.000 0.999 0.001
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.000 0.999 0.001
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.000 0.999 0.001
V40-V49 Car occupant injured in transport accident
0.000 0.999 0.001
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.000 0.999 0.001
V20-V29 Motorcycle rider injured in transport accident
0.000 0.999 0.001
V10-V19 Pedal cyclist injured in transport accident
0.000 0.999 0.001
V01-V09 Pedestrian injured in transport accident
0.000 0.999 0.001
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.000 0.999 0.001
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.000 0.999 0.001
Z09.2 Follow-up examination after chemotherapy for other conditions
0.000 0.999 0.001
Z09.0 Follow-up examination after surgery for other conditions
0.000 0.999 0.001
Z51.1 Chemotherapy session for neoplasm
0.000 0.999 0.001
Y43 Primarily systemic agents
0.000 0.999 0.001
Z44 Fitting and adjustment of external prosthetic device
0.000 0.999 0.001
A30-A49 Other bacterial diseases
0.000 0.999 0.001
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.999 0.001
D00-D09 In situ neoplasms
0.000 0.999 0.001
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.999 0.001
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.999 0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.999 0.001
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.999 0.001
C51-C58 Malignant neoplasms of female genital organs
0.000 0.999 0.001
C50-C50 Malignant neoplasm of breast
0.000 0.999 0.001
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.999 0.001
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.999 0.001
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.999 0.001
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.999 0.001
C15-C26 Malignant neoplasms of digestive organs
0.000 0.999 0.001
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.999 0.001
D80-D89 Certain disorders involving the immune mechanism
0.000 0.999 0.001
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.999 0.001
D55-D59 Haemolytic anaemias
0.000 0.999 0.001
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.999 0.001
H55-H59 Other disorders of eye and adnexa
0.000 0.999 0.001
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.999 0.001
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.999 0.001
H43-H45 Disorders of vitreous body and globe
0.000 0.999 0.001
H40-H42 Glaucoma
0.000 0.999 0.001
H30-H36 Disorders of choroid and retina
0.000 0.999 0.001
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.999 0.001
H10-H13 Disorders of conjunctiva
0.000 0.999 0.001
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.999 0.001
H80-H83 Diseases of inner ear
0.000 0.999 0.001
H65-H75 Diseases of middle ear and mastoid
0.000 0.999 0.001
H60-H62 Diseases of external ear
0.000 0.999 0.001
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.999 0.001
M70-M79 Other soft tissue disorders
0.000 0.999 0.001
N40-N51 Diseases of male genital organs
0.000 0.999 0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.000 0.999 0.001
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.999 0.001
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.000 0.999 0.001
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.999 0.001
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.000 0.999 0.001
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.000 0.999 0.001
R47-R49 Symptoms and signs involving speech and voice
0.000 0.999 0.001
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.999 0.001
R30-R39 Symptoms and signs involving the urinary system
0.000 0.999 0.001
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.999 0.001
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.000 0.999 0.001
Z86.4 Personal history of psychoactive substance abuse
0.000 0.999 0.001
Z86.0 Personal history of other neoplasms
0.000 0.999 0.001
Z87.8 Personal history of other specified conditions
0.000 0.999 0.001
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.999 0.001
Z87.6 Personal history of certain conditions arising in the perinatal period
0.000 0.999 0.001
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.000 0.999 0.001
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.000 0.999 0.001
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.000 0.999 0.001
Z87.0 Personal history of diseases of the respiratory system
0.000 0.999 0.001
H54 Blindness and low vision
0.000 0.999 0.001
N81 Female genital prolapse
0.000 0.999 0.001
Z29 Need for other prophylactic measures
0.000 0.999 0.001
Z28 Immunisation not carried out
0.000 0.999 0.001
Z27 Need for immunisation against combinations of infectious diseases
0.000 0.999 0.001
Z26 Need for immunisation against other single infectious diseases
0.000 0.999 0.001
Z25 Need for immunisation against other single viral diseases
0.000 0.999 0.001
Z24 Need for immunisation against certain single viral diseases
0.000 0.999 0.001
Z23 Need for immunisation against single bacterial diseases
0.000 0.999 0.001
Z22 Carrier of infectious disease
0.000 0.999 0.001
Z20 Contact with and exposure to communicable diseases
0.000 0.999 0.001
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.000 0.999 0.001
Z54 Convalescence
0.000 0.999 0.001
Z53 Persons encountering health services for specifie procedures, not carried out
0.000 0.999 0.001
Z52 Donors of organs and tissues
0.000 0.999 0.001
Z50 Care involving use of rehabilitation procedures
0.000 0.999 0.001
Z49 Care involving dialysis
0.000 0.999 0.001
Z48 Other surgical follow-up care
0.000 0.999 0.001
Z47 Other orthopaedic follow-up care
0.000 0.999 0.001
Z46 Fitting and adjustment of other devices
0.000 0.999 0.001
Z45 Adjustment and management of implanted device
0.000 0.999 0.001
Z43 Attention to artificial openings
0.000 0.999 0.001
Z42 Follow-up care involving plastic surgery
0.000 0.999 0.001
Z41 Procedures for purposes other than remedying health state
0.000 0.999 0.001
Z40 Prophylactic surgery
0.000 0.999 0.001
Z65 Problems related to other psychosocial circumstances
0.000 0.999 0.001
Z64 Problems related to certain psychosocial circumstances
0.000 0.999 0.001
Z63 Other problems related to primary support group, including family circumstances
0.000 0.999 0.001
Z62 Other problems related to upbringing
0.000 0.999 0.001
Z61 Problems related to negative life events in childhood
0.000 0.999 0.001
Z59 Problems related to housing and economic circumstances
0.000 0.999 0.001
Z58 Problems related to physical environment
0.000 0.999 0.001
Z57 Occupational exposure to risk-factors
0.000 0.999 0.001
Z56 Problems related to employment and unemployment
0.000 0.999 0.001
Z55 Problems related to education and literacy
0.000 0.999 0.001
B99-B99 Other infectious diseases
0.000 0.999 0.001
B95-B98 Bacterial, viral and other infectious agents
0.000 0.999 0.001
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.999 0.001
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.999 0.001
B65-B83 Helminthiases
0.000 0.999 0.001
B50-B64 Protozoal diseases
0.000 0.999 0.001
B35-B49 Mycoses
0.000 0.999 0.001
B25-B34 Other viral diseases
0.000 0.999 0.001
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.999 0.001
B15-B19 Viral hepatitis
0.000 0.999 0.001
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.999 0.001
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.999 0.001
A80-A89 Viral infections of the central nervous system
0.000 0.999 0.001
A75-A79 Rickettsioses
0.000 0.999 0.001
A70-A74 Other diseases caused by chlamydiae
0.000 0.999 0.001
A65-A69 Other spirochaetal diseases
0.000 0.999 0.001
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.999 0.001
A20-A28 Certain zoonotic bacterial diseases
0.000 0.999 0.001
A15-A19 Tuberculosis
0.000 0.999 0.001
A00-A09 Intestinal infectious diseases
0.000 0.999 0.001
D10-D36 Benign neoplasms
0.000 0.999 0.001
D60-D64 Aplastic and other anaemias
0.000 0.999 0.001
D50-D53 Nutritional anaemias
0.000 0.999 0.001
E70-E90 Metabolic disorders
0.000 0.999 0.001
E65-E68 Obesity and other hyperalimentation
0.000 0.999 0.001
E50-E64 Other nutritional deficiencies
0.000 0.999 0.001
E40-E46 Malnutrition
0.000 0.999 0.001
E20-E35 Disorders of other endocrine glands
0.000 0.999 0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.999 0.001
E10-E14 Diabetes mellitus
0.000 0.999 0.001
E00-E07 Disorders of thyroid gland
0.000 0.999 0.001
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.999 0.001
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.999 0.001
I60-I69 Cerebrovascular diseases
0.000 0.999 0.001
I30-I52 Other forms of heart disease
0.000 0.999 0.001
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.999 0.001
I20-I25 Ischaemic heart diseases
0.000 0.999 0.001
I10-I15 Hypertensive diseases
0.000 0.999 0.001
I05-I09 Chronic rheumatic heart diseases
0.000 0.999 0.001
I00-I02 Acute rheumatic fever
0.000 0.999 0.001
F99-F99 Unspecified mental disorder
0.000 0.999 0.001
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.999 0.001
F80-F89 Disorders of psychological development
0.000 0.999 0.001
F70-F79 Mental retardation
0.000 0.999 0.001
F60-F69 Disorders of adult personality and behaviour
0.000 0.999 0.001
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.999 0.001
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.999 0.001
F30-F39 Mood [affective] disorders
0.000 0.999 0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.999 0.001
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.999 0.001
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.999 0.001
G90-G99 Other disorders of the nervous system
0.000 0.999 0.001
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.999 0.001
G70-G73 Diseases of myoneural junction and muscle
0.000 0.999 0.001
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.999 0.001
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.999 0.001
G40-G47 Episodic and paroxysmal disorders
0.000 0.999 0.001
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.999 0.001
G30-G32 Other degenerative diseases of the nervous system
0.000 0.999 0.001
G20-G26 Extrapyramidal and movement disorders
0.000 0.999 0.001
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.999 0.001
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.999 0.001
J95-J99 Other diseases of the respiratory system
0.000 0.999 0.001
J90-J94 Other diseases of pleura
0.000 0.999 0.001
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.999 0.001
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.999 0.001
J60-J70 Lung diseases due to external agents
0.000 0.999 0.001
J40-J47 Chronic lower respiratory diseases
0.000 0.999 0.001
J30-J39 Other diseases of upper respiratory tract
0.000 0.999 0.001
J20-J22 Other acute lower respiratory infections
0.000 0.999 0.001
J09-J18 Influenza and pneumonia
0.000 0.999 0.001
J00-J06 Acute upper respiratory infections
0.000 0.999 0.001
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.999 0.001
L60-L75 Disorders of skin appendages
0.000 0.999 0.001
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.999 0.001
L50-L54 Urticaria and erythema
0.000 0.999 0.001
L40-L45 Papulosquamous disorders
0.000 0.999 0.001
L20-L30 Dermatitis and eczema
0.000 0.999 0.001
L10-L14 Bullous disorders
0.000 0.999 0.001
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.999 0.001
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.999 0.001
M91-M94 Chondropathies
0.000 0.999 0.001
M86-M90 Other osteopathies
0.000 0.999 0.001
M80-M85 Disorders of bone density and structure
0.000 0.999 0.001
M65-M68 Disorders of synovium and tendon
0.000 0.999 0.001
M60-M63 Disorders of muscles
0.000 0.999 0.001
M50-M54 Other dorsopathies
0.000 0.999 0.001
M45-M49 Spondylopathies
0.000 0.999 0.001
M40-M43 Deforming dorsopathies
0.000 0.999 0.001
M20-M25 Other joint disorders
0.000 0.999 0.001
M05-M14 Inflammatory polyarthropathies
0.000 0.999 0.001
M00-M03 Infectious arthropathies
0.000 0.999 0.001
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.000 0.999 0.001
T79-T79 Certain early complications of trauma
0.000 0.999 0.001
T66-T78 Other and unspecified effects of external causes
0.000 0.999 0.001
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.000 0.999 0.001
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.999 0.001
T33-T35 Frostbite
0.000 0.999 0.001
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.000 0.999 0.001
T26-T28 Burns and corrosions confined to eye and internal organs
0.000 0.999 0.001
T20-T25 Burns and corrosions of external body surface, specified by site
0.000 0.999 0.001
T15-T19 Effects of foreign body entering through natural orifice
0.000 0.999 0.001
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.000 0.999 0.001
T00-T07 Injuries involving multiple body regions
0.000 0.999 0.001
S90-S99 Injuries to the ankle and foot
0.000 0.999 0.001
S80-S89 Injuries to the knee and lower leg
0.000 0.999 0.001
S70-S79 Injuries to the hip and thigh
0.000 0.999 0.001
S60-S69 Injuries to the wrist and hand
0.000 0.999 0.001
S50-S59 Injuries to the elbow and forearm
0.000 0.999 0.001
S40-S49 Injuries to the shoulder and upper arm
0.000 0.999 0.001
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.000 0.999 0.001
S20-S29 Injuries to the thorax
0.000 0.999 0.001
S10-S19 Injuries to the neck
0.000 0.999 0.001
S00-S09 Injuries to the head
0.000 0.999 0.001
O94-O99 Other obstetric conditions, not elsewhere classified
0.000 0.999 0.001
O85-O92 Complications predominantly related to the puerperium
0.000 0.999 0.001
O80-O84 Delivery
0.000 0.999 0.001
O60-O75 Complications of labour and delivery
0.000 0.999 0.001
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.000 0.999 0.001
O20-O29 Other maternal disorders predominantly related to pregnancy
0.000 0.999 0.001
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.000 0.999 0.001
O00-O08 Pregnancy with abortive outcome
0.000 0.999 0.001
P90-P96 Other disorders originating in the perinatal period
0.000 0.999 0.001
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.999 0.001
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.999 0.001
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.999 0.001
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.999 0.001
P35-P39 Infections specific to the perinatal period
0.000 0.999 0.001
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.999 0.001
P10-P15 Birth trauma
0.000 0.999 0.001
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.999 0.001
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.999 0.001
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.999 0.001
Q80-Q89 Other congenital malformations
0.000 0.999 0.001
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.000 0.999 0.001
Q60-Q64 Congenital malformations of the urinary system
0.000 0.999 0.001
Q50-Q56 Congenital malformations of genital organs
0.000 0.999 0.001
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.999 0.001
Q35-Q37 Cleft lip and cleft palate
0.000 0.999 0.001
Q30-Q34 Congenital malformations of the respiratory system
0.000 0.999 0.001
Q20-Q28 Congenital malformations of the circulatory system
0.000 0.999 0.001
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.000 0.999 0.001
Q00-Q07 Congenital malformations of the nervous system
0.000 0.999 0.001
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.999 0.001
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.999 0.001
Y43.3 Other antineoplastic drugs
0.000 0.999 0.001
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.000 0.999 0.001
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.000 0.999 0.001
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.000 0.999 0.001
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.000 0.999 0.001
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.000 0.999 0.001
Z09.8 Follow-up examination after other treatment for other conditions
0.000 0.999 0.001
Z09.7 Follow-up examination after combined treatment for other conditions
0.000 0.999 0.001
Z09.4 Follow-up examination after treatment of fracture
0.000 0.999 0.001
Z09.3 Follow-up examination after psychotherapy
0.000 0.999 0.001
Z09.1 Follow-up examination after radiotherapy for other conditions
0.000 0.999 0.001
Z85.5 Personal history of malignant neoplasm of urinary tract
0.000 0.999 0.001
Z86.6 Personal history of diseases of the nervous system and sense organs
0.000 0.999 0.001
Z86.5 Personal history of other mental and behavioural disorders
0.000 0.999 0.001
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.999 0.001
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.999 0.001
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.999 0.001
C61 Malignant neoplasm of prostate
0.000 0.999 0.001
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.999 0.001
H91 Other hearing loss
0.000 0.999 0.001
N85 Other noninflammatory disorders of uterus, except cervix
0.000 0.999 0.001
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.000 0.999 0.001
Y59 Other and unspecified vaccines and biological substances
0.000 0.999 0.001
Y58 Bacterial vaccines
0.000 0.999 0.001
Y57 Other and unspecified drugs and medicaments
0.000 0.999 0.001
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.000 0.999 0.001
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.999 0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.000 0.999 0.001
Y53 Agents primarily affecting the gastro-intestinal system
0.000 0.999 0.001
Y52 Agents primarily affecting the cardiovascular system
0.000 0.999 0.001
Y51 Drugs primarily affecting the autonomic nervous system
0.000 0.999 0.001
Y50 Central nervous system stimulants, not elsewhere classified
0.000 0.999 0.001
Y49 Psychotropic drugs, not elsewhere classified
0.000 0.999 0.001
Y48 Anaesthetics and therapeutic gases
0.000 0.999 0.001
Y47 Sedatives, hypnotics and antianxiety drugs
0.000 0.999 0.001
Y46 Antiepileptics and anti-Parkinsonism drugs
0.000 0.999 0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.000 0.999 0.001
Y44 Agents primarily affecting blood constituents
0.000 0.999 0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.999 0.001
Y41 Other systemic anti-infectives and antiparasitics
0.000 0.999 0.001
Y40 Systemic antibiotics
0.000 0.999 0.001
Z39 Postpartum care and examination
0.000 0.999 0.001
Z38 Liveborn infants according to place of birth
0.000 0.999 0.001
Z37 Outcome of delivery
0.000 0.999 0.001
Z36 Antenatal screening
0.000 0.999 0.001
Z35 Supervision of high-risk pregnancy
0.000 0.999 0.001
Z34 Supervision of normal pregnancy
0.000 0.999 0.001
Z32 Pregnancy examination and test
0.000 0.999 0.001
Z31 Procreative management
0.000 0.999 0.001
Z30 Contraceptive management
0.000 0.999 0.001
Z33 Pregnant state, incidental
0.000 0.999 0.001
Z60 Problems related to social environment
0.000 0.999 0.001
Z76 Persons encountering health services in other circumstances
0.000 0.999 0.001
Z75 Problems related to medical facilities and other health care
0.000 0.999 0.001
Z74 Problems related to care-provider dependency
0.000 0.999 0.001
Z73 Problems related to life-management difficulty
0.000 0.999 0.001
Z72 Problems related to lifestyle
0.000 0.999 0.001
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.000 0.999 0.001
Z70 Counselling related to sexual attitude, behaviour and orientation
0.000 0.999 0.001
K90-K93 Other diseases of the digestive system
0.000 0.999 0.001
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.999 0.001
K70-K77 Diseases of liver
0.000 0.999 0.001
K65-K67 Diseases of peritoneum
0.000 0.999 0.001
K50-K52 Noninfective enteritis and colitis
0.000 0.999 0.001
K40-K46 Hernia
0.000 0.999 0.001
K35-K38 Diseases of appendix
0.000 0.999 0.001
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.000 0.999 0.001
M15-M19 Arthrosis
0.000 0.999 0.001
Z00.8 Other general examinations
0.000 0.999 0.001
Z00.6 Examination for normal comparison and control in clinical research programme
0.000 0.999 0.001
Z00.5 Examination of potential donor of organ and tissue
0.000 0.999 0.001
Z00.4 General psychiatric examination, not elsewhere classified
0.000 0.999 0.001
Z00.3 Examination for adolescent development state
0.000 0.999 0.001
Z00.2 Examination for period of rapid growth in childhood
0.000 0.999 0.001
Z00.1 Routine child health examination
0.000 0.999 0.001
Z00.0 General medical examination
0.000 0.999 0.001
Z01.9 Special examination, unspecified
0.000 0.999 0.001
Z01.8 Other specified special examinations
0.000 0.999 0.001
Z01.7 Laboratory examination
0.000 0.999 0.001
Z01.6 Radiological examination, not elsewhere classified
0.000 0.999 0.001
Z01.5 Diagnostic skin and sensitisation tests
0.000 0.999 0.001
Z01.4 Gynaecological examination (general)(routine)
0.000 0.999 0.001
Z01.3 Examination of blood pressure
0.000 0.999 0.001
Z01.2 Dental examination
0.000 0.999 0.001
Z01.1 Examination of ears and hearing
0.000 0.999 0.001
Z01.0 Examination of eyes and vision
0.000 0.999 0.001
Z02.9 Examination for administrative purposes, unspecified
0.000 0.999 0.001
Z02.8 Other examinations for administrative purposes
0.000 0.999 0.001
Z02.7 Issue of medical certificate
0.000 0.999 0.001
Z02.6 Examination for insurance purposes
0.000 0.999 0.001
Z02.5 Examination for participation in sport
0.000 0.999 0.001
Z02.4 Examination for driving licence
0.000 0.999 0.001
Z02.3 Examination for recruitment to armed forces
0.000 0.999 0.001
Z02.2 Examination for admission to residential institution
0.000 0.999 0.001
Z02.1 Pre-employment examination
0.000 0.999 0.001
Z02.0 Examination for admission to educational institution
0.000 0.999 0.001
Z03.9 Observation for suspected disease or condition, unspecified
0.000 0.999 0.001
Z03.6 Observation for suspected toxic effect from ingested substance
0.000 0.999 0.001
Z03.5 Observation for other suspected cardiovascular diseases
0.000 0.999 0.001
Z03.4 Observation for suspected myocardial infarction
0.000 0.999 0.001
Z03.3 Observation for suspected nervous system disorder
0.000 0.999 0.001
Z03.2 Observation for suspected mental and behavioural disorders
0.000 0.999 0.001
Z03.1 Observation for suspected malignant neoplasm
0.000 0.999 0.001
Z03.0 Observation for suspected tuberculosis
0.000 0.999 0.001
Z04.9 Examination and observation for unspecified reason
0.000 0.999 0.001
Z04.8 Examination and observation for other specified reasons
0.000 0.999 0.001
Z04.6 General psychiatric examination, requested by authority
0.000 0.999 0.001
Z04.5 Examination and observation following other inflicted injury
0.000 0.999 0.001
Z04.4 Examination and observation following alleged rape and seduction
0.000 0.999 0.001
Z04.3 Examination and observation following other accident
0.000 0.999 0.001
Z04.2 Examination and observation following work accident
0.000 0.999 0.001
Z04.1 Examination and observation following transport accident
0.000 0.999 0.001
Z04.0 Blood-alcohol and blood-drug test
0.000 0.999 0.001
Z10.8 Routine general health check-up of other defined subpopulations
0.000 0.999 0.001
Z10.3 Routine general health check-up of sports teams
0.000 0.999 0.001
Z10.2 Routine general health check-up of armed forces
0.000 0.999 0.001
Z10.1 Routine general health check-up of inhabitants of institutions
0.000 0.999 0.001
Z10.0 Occupational health examination
0.000 0.999 0.001
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified
0.000 0.999 0.001
Z11.8 Special screening examination for other infectious and parasitic diseases
0.000 0.999 0.001
Z11.6 Special screening examination for other protozoal diseases and helminthiases
0.000 0.999 0.001
Z11.5 Special screening examination for other viral diseases
0.000 0.999 0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.000 0.999 0.001
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission
0.000 0.999 0.001
Z11.2 Special screening examination for other bacterial diseases
0.000 0.999 0.001
Z11.1 Special screening examination for respiratory tuberculosis
0.000 0.999 0.001
Z11.0 Special screening examination for intestinal infectious diseases
0.000 0.999 0.001
Z12.9 Special screening examination for neoplasm, unspecified
0.000 0.999 0.001
Z12.8 Special screening examination for neoplasm of other sites
0.000 0.999 0.001
Z12.6 Special screening examination for neoplasm of bladder
0.000 0.999 0.001
Z12.5 Special screening examination for neoplasm of prostate
0.000 0.999 0.001
Z12.4 Special screening examination for neoplasm of cervix
0.000 0.999 0.001
Z12.3 Special screening examination for neoplasm of breast
0.000 0.999 0.001
Z12.2 Special screening examination for neoplasm of respiratory organs
0.000 0.999 0.001
Z12.1 Special screening examination for neoplasm of intestinal tract
0.000 0.999 0.001
Z12.0 Special screening examination for neoplasm of stomach
0.000 0.999 0.001
Z13.8 Special screening examination for other specified diseases and disorders
0.000 0.999 0.001
Z13.9 Special screening examination, unspecified
0.000 0.999 0.001
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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