TreeWAS – Variant ID: rs73660508

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
Chapter X Diseases of the respiratory system	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.997	0.003
J09-J18 Influenza and pneumonia	0.995	0.005
M20-M25 Other joint disorders	0.989	0.011
M05-M14 Inflammatory polyarthropathies	0.986	0.014
H60-H62 Diseases of external ear	0.983	0.017
M80-M85 Disorders of bone density and structure	0.983	0.017
M06 Other rheumatoid arthritis	0.971	0.029
J18 Pneumonia, organism unspecified	0.970	0.030
H60 Otitis externa	0.969	0.031
M24 Other specific joint derangements	0.967	0.033
M86-M90 Other osteopathies	0.967	0.033
M80 Osteoporosis with pathological fracture	0.962	0.038
M06.9 Rheumatoid arthritis, unspecified	0.959	0.041
J95-J99 Other diseases of the respiratory system	0.947	0.053
H72 Perforation of tympanic membrane	0.943	0.057
M40-M43 Deforming dorsopathies	0.938	0.062
H60.9 Otitis externa, unspecified	0.937	0.063
M80.9 Unspecified osteoporosis with pathological fracture	0.936	0.064
J18.9 Pneumonia, unspecified	0.936	0.064
Chapter I Certain infectious and parasitic diseases	0.934	0.066
M21 Other acquired deformities of limbs	0.929	0.071
H73 Other disorders of tympanic membrane	0.925	0.075
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.924	0.076
Chapter IV Endocrine, nutritional and metabolic diseases	0.924	0.076
J10 Influenza due to identified influenza virus	0.917	0.083
J80-J84 Other respiratory diseases principally affecting the interstitium	0.916	0.084
M87 Osteonecrosis	0.913	0.087
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.909	0.091
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.908	0.092
H72.9 Perforation of tympanic membrane, unspecified	0.903	0.097
M60-M63 Disorders of muscles	0.903	0.097
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.900	0.100
E65-E68 Obesity and other hyperalimentation	0.900	0.100
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.897	0.103
M24.2 Disorder of ligament	0.897	0.103
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.889	0.111
M41 Scoliosis	0.886	0.114
R25 Abnormal involuntary movements	0.885	0.115
E66 Obesity	0.882	0.118
Chapter XX External causes of morbidity and mortality	0.879	0.121
M22 Disorders of patella	0.879	0.121
M24.0 Loose body in joint	0.878	0.122
M87.9 Osteonecrosis, unspecified	0.877	0.123
Chapter IX Diseases of the circulatory system	0.869	0.131
H73.8 Other specified disorders of tympanic membrane	0.865	0.135
M10 Gout	0.861	0.139
M91-M94 Chondropathies	0.859	0.140
J15 Bacterial pneumonia, not elsewhere classified	0.859	0.141
E66.8 Other obesity	0.859	0.141
A30-A49 Other bacterial diseases	0.852	0.148
B95-B98 Bacterial, viral and other infectious agents	0.851	0.149
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.851	0.149
H66 Suppurative and unspecified otitis media	0.850	0.150
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.848	0.152
M70-M79 Other soft tissue disorders	0.848	0.152
M41.9 Scoliosis, unspecified	0.845	0.155
J18.8 Other pneumonia, organism unspecified	0.844	0.156
E20-E35 Disorders of other endocrine glands	0.843	0.157
H74 Other disorders of middle ear and mastoid	0.838	0.162
J95 Postprocedural respiratory disorders, not elsewhere classified	0.838	0.162
S90-S99 Injuries to the ankle and foot	0.837	0.163
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.836	0.164
H60.3 Other infective otitis externa	0.835	0.165
M62 Other disorders of muscle	0.833	0.167
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.831	0.169
J20-J22 Other acute lower respiratory infections	0.828	0.172
J98 Other respiratory disorders	0.828	0.172
M86 Osteomyelitis	0.826	0.174
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.825	0.175
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.825	0.175
R29.6 Tendency to fall, not elsewhere classified	0.824	0.176
M21.3 Wrist or foot drop (acquired)	0.824	0.176
H65 Nonsuppurative otitis media	0.820	0.180
M81 Osteoporosis without pathological fracture	0.819	0.181
M80.8 Other osteoporosis with pathological fracture	0.817	0.183
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.817	0.183
J10.0 Influenza with pneumonia, influenza virus identified	0.815	0.185
A41 Other septicaemia	0.815	0.185
Chapter XXI Factors influencing health status and contact with health services	0.813	0.187
M31 Other necrotising vasculopathies	0.812	0.188
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.812	0.188
H69 Other disorders of Eustachian tube	0.811	0.189
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.805	0.195
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.804	0.196
M21.6 Other acquired deformities of ankle and foot	0.804	0.196
E50-E64 Other nutritional deficiencies	0.799	0.201
H60.1 Cellulitis of external ear	0.799	0.201
I27 Other pulmonary heart diseases	0.798	0.202
I95-I99 Other and unspecified disorders of the circulatory system	0.797	0.203
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.797	0.203
M22.8 Other disorders of patella	0.794	0.206
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.794	0.206
J80 Adult respiratory distress syndrome	0.793	0.207
R25.1 Tremor, unspecified	0.793	0.207
A41.5 Septicaemia due to other Gram-negative organisms	0.788	0.212
M24.5 Contracture of joint	0.786	0.214
J17 Pneumonia in diseases classified elsewhere	0.785	0.215
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.785	0.215
M62.8 Other specified disorders of muscle	0.783	0.217
I05-I09 Chronic rheumatic heart diseases	0.783	0.217
R76 Other abnormal immunological findings in serum	0.781	0.219
R25.8 Other and unspecified abnormal involuntary movements	0.779	0.221
M07 Psoriatic and enteropathic arthropathies	0.778	0.221
T36-T50 Poisoning by drugs, medicaments and biological substances	0.778	0.222
M24.01 Loose body in joint (Shoulder region)	0.777	0.223
R47-R49 Symptoms and signs involving speech and voice	0.777	0.223
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.777	0.223
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.775	0.225
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.775	0.225
M65-M68 Disorders of synovium and tendon	0.775	0.225
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.774	0.226
M24.27 Disorder of ligament (Ankle and foot)	0.772	0.228
M41.99 Scoliosis, unspecified (Site unspecified)	0.772	0.228
M10.9 Gout, unspecified	0.770	0.230
H66.9 Otitis media, unspecified	0.769	0.231
J84 Other interstitial pulmonary diseases	0.767	0.233
M06.3 Rheumatoid nodule	0.766	0.234
Z36 Antenatal screening	0.765	0.235
S10-S19 Injuries to the neck	0.764	0.236
R76.8 Other specified abnormal immunological findings in serum	0.761	0.239
B90-B94 Sequelae of infectious and parasitic diseases	0.760	0.240
J13 Pneumonia due to Streptococcus pneumoniae	0.759	0.240
Y95 Nosocomial condition	0.758	0.242
R26 Abnormalities of gait and mobility	0.758	0.242
Z57 Occupational exposure to risk-factors	0.757	0.243
M33 Dermatopolymyositis	0.757	0.243
M85 Other disorders of bone density and structure	0.756	0.244
H72.8 Other perforations of tympanic membrane	0.755	0.245
X40-X49 Accidental poisoning by and exposure to noxious substances	0.755	0.245
I30-I52 Other forms of heart disease	0.755	0.245
T79-T79 Certain early complications of trauma	0.753	0.247
R82 Other abnormal findings in urine	0.753	0.247
M05 Seropositive rheumatoid arthritis	0.751	0.249
T20-T25 Burns and corrosions of external body surface, specified by site	0.751	0.249
B35-B49 Mycoses	0.751	0.249
J98.0 Diseases of bronchus, not elsewhere classified	0.750	0.250
H61 Other disorders of external ear	0.750	0.250
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.749	0.251
A41.0 Septicaemia due to Staphylococcus aureus	0.749	0.251
E28 Ovarian dysfunction	0.747	0.253
M35 Other systemic involvement of connective tissue	0.747	0.253
R25.2 Cramp and spasm	0.746	0.253
M72 Fibroblastic disorders	0.746	0.254
S20-S29 Injuries to the thorax	0.744	0.256
H72.2 Other marginal perforations of tympanic membrane	0.744	0.256
J99 Respiratory disorders in diseases classified elsewhere	0.744	0.256
H71 Cholesteatoma of middle ear	0.742	0.258
B25-B34 Other viral diseases	0.740	0.260
E55 Vitamin D deficiency	0.740	0.260
J14 Pneumonia due to Haemophilus influenzae	0.739	0.261
R49 Voice disturbances	0.739	0.261
J95.8 Other postprocedural respiratory disorders	0.738	0.262
H65.9 Nonsuppurative otitis media, unspecified	0.735	0.265
M82 Osteoporosis in diseases classified elsewhere	0.734	0.266
M21.1 Varus deformity, not elsewhere classified	0.733	0.267
J15.4 Pneumonia due to other streptococci	0.733	0.267
M00-M03 Infectious arthropathies	0.731	0.268
S00-S09 Injuries to the head	0.730	0.270
Z33 Pregnant state, incidental	0.730	0.270
I27.0 Primary pulmonary hypertension	0.730	0.270
S00 Superficial injury of head	0.729	0.271
S92 Fracture of foot, except ankle	0.727	0.273
W50-W64 Exposure to animate mechanical forces	0.727	0.273
M88 Paget's disease of bone [osteitis deformans]	0.725	0.275
M06.0 Seronegative rheumatoid arthritis	0.725	0.275
H74.3 Other acquired abnormalities of ear ossicles	0.724	0.276
B15-B19 Viral hepatitis	0.723	0.277
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.720	0.280
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.720	0.280
M94 Other disorders of cartilage	0.719	0.281
X60-X84 Intentional self-harm	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M62.86 Other specified disorders of muscle (Lower leg)	0.717	0.283
M24.28 Disorder of ligament (Other)	0.716	0.284
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.715	0.285
H68 Eustachian salpingitis and obstruction	0.715	0.285
H67 Otitis media in diseases classified elsewhere	0.715	0.285
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.714	0.286
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.714	0.286
M80.88 Other osteoporosis with pathological fracture (Other)	0.714	0.286
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.713	0.287
J12 Viral pneumonia, not elsewhere classified	0.713	0.287
J09 Influenza due to certain identified influenza virus	0.713	0.287
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.712	0.288
M40 Kyphosis and lordosis	0.712	0.288
M89 Other disorders of bone	0.712	0.288
B65-B83 Helminthiases	0.711	0.288
I46 Cardiac arrest	0.710	0.290
J30-J39 Other diseases of upper respiratory tract	0.709	0.291
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291
M32 Systemic lupus erythematosus	0.709	0.291
M30 Polyarteritis nodosa and related conditions	0.709	0.291
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.709	0.291
S00.8 Superficial injury of other parts of head	0.708	0.292
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.708	0.292
M80.5 Idiopathic osteoporosis with pathological fracture	0.708	0.292
M12 Other specific arthropathies	0.707	0.293
M09 Juvenile arthritis in diseases classified elsewhere	0.707	0.293
M08 Juvenile arthritis	0.707	0.293
M81.4 Drug-induced osteoporosis	0.707	0.293
M24.4 Recurrent dislocation and subluxation of joint	0.706	0.294
H62 Disorders of external ear in diseases classified elsewhere	0.705	0.295
M83 Adult osteomalacia	0.705	0.295
T15-T19 Effects of foreign body entering through natural orifice	0.705	0.295
J18.0 Bronchopneumonia, unspecified	0.704	0.296
J98.1 Pulmonary collapse	0.704	0.296
M24.23 Disorder of ligament (Forearm)	0.703	0.297
Z57.2 Occupational exposure to dust	0.702	0.298
M77 Other enthesopathies	0.701	0.299
H73.9 Disorder of tympanic membrane, unspecified	0.699	0.301
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.699	0.301
M71 Other bursopathies	0.698	0.302
E55.9 Vitamin D deficiency, unspecified	0.697	0.303
M24.07 Loose body in joint (Ankle and foot)	0.697	0.303
Z30 Contraceptive management	0.697	0.303
I45 Other conduction disorders	0.697	0.303
M06.8 Other specified rheumatoid arthritis	0.696	0.304
M06.2 Rheumatoid bursitis	0.696	0.304
M06.1 Adult-onset Still's disease	0.696	0.304
S90 Superficial injury of ankle and foot	0.696	0.304
J18.2 Hypostatic pneumonia, unspecified	0.695	0.304
H60.8 Other otitis externa	0.695	0.305
H60.5 Acute otitis externa, non-infective	0.695	0.305
H60.4 Cholesteatoma of external ear	0.695	0.305
H60.2 Malignant otitis externa	0.695	0.305
H60.0 Abscess of external ear	0.695	0.305
X20-X29 Contact with venomous animals and plants	0.694	0.306
M24.9 Joint derangement, unspecified	0.693	0.306
M24.7 Protrusio acetabuli	0.693	0.306
M24.6 Ankylosis of joint	0.693	0.306
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.693	0.306
H70 Mastoiditis and related conditions	0.693	0.307
T00-T07 Injuries involving multiple body regions	0.693	0.307
M21.2 Flexion deformity	0.693	0.307
S32 Fracture of lumbar spine and pelvis	0.693	0.307
M24.24 Disorder of ligament (Hand)	0.692	0.308
A49 Bacterial infection of unspecified site	0.691	0.309
M80.4 Drug-induced osteoporosis with pathological fracture	0.689	0.310
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.689	0.310
M80.2 Osteoporosis of disuse with pathological fracture	0.689	0.310
M24.8 Other specific joint derangements, not elsewhere classified	0.689	0.311
B50-B64 Protozoal diseases	0.689	0.311
E66.2 Extreme obesity with alveolar hypoventilation	0.688	0.312
M06.98 Rheumatoid arthritis, unspecified (Other)	0.688	0.312
V70-V79 Bus occupant injured in transport accident	0.688	0.312
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.688	0.312
Z57.5 Occupational exposure to toxic agents in other industries	0.687	0.313
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.685	0.315
M93 Other osteochondropathies	0.685	0.315
X10-X19 Contact with heat and hot substances	0.684	0.316
J20 Acute bronchitis	0.684	0.316
T46 Poisoning by agents primarily affecting the cardiovascular system	0.684	0.316
M86.9 Osteomyelitis, unspecified	0.683	0.317
M90 Osteopathies in diseases classified elsewhere	0.683	0.317
M14 Arthropathies in other diseases classified elsewhere	0.682	0.317
I08 Multiple valve diseases	0.682	0.318
R25.3 Fasciculation	0.682	0.318
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.682	0.318
I46.0 Cardiac arrest with successful resuscitation	0.682	0.318
J15.2 Pneumonia due to staphylococcus	0.680	0.320
J81 Pulmonary oedema	0.680	0.320
E66.9 Obesity, unspecified	0.680	0.320
E22 Hyperfunction of pituitary gland	0.680	0.320
M20 Acquired deformities of fingers and toes	0.679	0.321
J96 Respiratory failure, not elsewhere classified	0.679	0.321
M24.1 Other articular cartilage disorders	0.679	0.321
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.678	0.322
M43 Other deforming dorsopathies	0.678	0.322
I38 Endocarditis, valve unspecified	0.678	0.322
J82 Pulmonary eosinophilia, not elsewhere classified	0.677	0.323
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.677	0.323
H72.1 Attic perforation of tympanic membrane	0.676	0.324
E66.0 Obesity due to excess calories	0.676	0.324
J30 Vasomotor and allergic rhinitis	0.674	0.326
M42 Spinal osteochondrosis	0.673	0.327
J40-J47 Chronic lower respiratory diseases	0.673	0.327
R49.0 Dysphonia	0.672	0.328
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.671	0.329
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.671	0.329
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.671	0.329
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.671	0.329
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.671	0.329
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.671	0.329
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.671	0.329
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.671	0.329
M34 Systemic sclerosis	0.670	0.329
B85-B89 Pediculosis, acariasis and other infestations	0.670	0.330
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.670	0.330
A75-A79 Rickettsioses	0.670	0.330
A70-A74 Other diseases caused by chlamydiae	0.670	0.330
A65-A69 Other spirochaetal diseases	0.670	0.330
A20-A28 Certain zoonotic bacterial diseases	0.670	0.330
A15-A19 Tuberculosis	0.670	0.330
V01-V09 Pedestrian injured in transport accident	0.670	0.330
H69.9 Eustachian tube disorder, unspecified	0.670	0.330
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.670	0.330
I27.2 Other secondary pulmonary hypertension	0.669	0.331
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.669	0.331
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.668	0.332
M70 Soft tissue disorders related to use, overuse and pressure	0.668	0.332
E28.2 Polycystic ovarian syndrome	0.668	0.332
I27.9 Pulmonary heart disease, unspecified	0.667	0.332
I31 Other diseases of pericardium	0.667	0.333
R82.8 Abnormal findings on cytological and histological examination of urine	0.667	0.333
R26.2 Difficulty in walking, not elsewhere classified	0.666	0.334
M21.9 Acquired deformity of limb, unspecified	0.666	0.334
M21.8 Other specified acquired deformities of limbs	0.666	0.334
M21.7 Unequal limb length (acquired)	0.666	0.334
A50-A64 Infections with a predominantly sexual mode of transmission	0.666	0.334
E40-E46 Malnutrition	0.665	0.335
W20-W49 Exposure to inanimate mechanical forces	0.664	0.335
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.663	0.336
H73.1 Chronic myringitis	0.663	0.337
H73.0 Acute myringitis	0.663	0.337
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.663	0.337
H74.0 Tympanosclerosis	0.662	0.338
M11 Other crystal arthropathies	0.662	0.338
M10.96 Gout, unspecified (Lower leg)	0.662	0.338
M41.94 Scoliosis, unspecified (Thoracic region)	0.661	0.338
M24.26 Disorder of ligament (Lower leg)	0.661	0.338
M86.6 Other chronic osteomyelitis	0.661	0.339
M21.4 Flat foot [pes planus] (acquired)	0.661	0.339
M67 Other disorders of synovium and tendon	0.661	0.339
R82.9 Other and unspecified abnormal finding in urine	0.659	0.341
M62.89 Other specified disorders of muscle (Site unspecified)	0.659	0.341
M24.02 Loose body in joint (Upper arm)	0.659	0.341
J10.8 Influenza with other manifestations, influenza virus identified	0.657	0.342
Z36.8 Other antenatal screening	0.657	0.343
S00.1 Contusion of eyelid and periocular area	0.656	0.344
J18.1 Lobar pneumonia, unspecified	0.656	0.344
M41.96 Scoliosis, unspecified (Lumbar region)	0.655	0.345
M87.8 Other osteonecrosis	0.654	0.346
M87.3 Other secondary osteonecrosis	0.654	0.346
M87.1 Osteonecrosis due to drugs	0.654	0.346
M87.0 Idiopathic aseptic necrosis of bone	0.654	0.346
M22.4 Chondromalacia patellae	0.654	0.346
M62.80 Other specified disorders of muscle (Multiple sites)	0.654	0.346
M31.9 Necrotising vasculopathy, unspecified	0.653	0.347
B44 Aspergillosis	0.653	0.347
M41.8 Other forms of scoliosis	0.652	0.347
M10.92 Gout, unspecified (Upper arm)	0.652	0.347
J95.0 Tracheostomy malfunction	0.652	0.348
R27 Other lack of coordination	0.652	0.348
Y00-Y09 Assault	0.652	0.348
R95-R99 Ill-defined and unknown causes of mortality	0.651	0.349
T79 Certain early complications of trauma, not elsewhere classified	0.651	0.349
S60-S69 Injuries to the wrist and hand	0.649	0.351
E34 Other endocrine disorders	0.649	0.351
M31.3 Wegener's granulomatosis	0.648	0.352
M63 Disorders of muscle in diseases classified elsewhere	0.647	0.353
M61 Calcification and ossification of muscle	0.647	0.353
M60 Myositis	0.647	0.353
J15.1 Pneumonia due to Pseudomonas	0.647	0.353
J84.1 Other interstitial pulmonary diseases with fibrosis	0.645	0.355
V10-V19 Pedal cyclist injured in transport accident	0.645	0.355
E67 Other hyperalimentation	0.645	0.355
E68 Sequelae of hyperalimentation	0.645	0.355
J30.1 Allergic rhinitis due to pollen	0.645	0.355
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.644	0.356
M80.0 Postmenopausal osteoporosis with pathological fracture	0.643	0.357
I28 Other diseases of pulmonary vessels	0.643	0.357
T33-T35 Frostbite	0.643	0.357
T26-T28 Burns and corrosions confined to eye and internal organs	0.643	0.357
M24.29 Disorder of ligament (Site unspecified)	0.643	0.357
M24.25 Disorder of ligament (Pelvic region and thigh)	0.643	0.357
M24.22 Disorder of ligament (Upper arm)	0.643	0.357
M24.21 Disorder of ligament (Shoulder region)	0.643	0.357
M24.20 Disorder of ligament (Multiple sites)	0.643	0.357
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.642	0.358
M22.2 Patellofemoral disorders	0.642	0.358
E65 Localised adiposity	0.642	0.358
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.641	0.359
S91 Open wound of ankle and foot	0.640	0.360
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.639	0.361
A39 Meningococcal infection	0.639	0.361
J36 Peritonsillar abscess	0.639	0.361
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.638	0.362
Y91 Evidence of alcohol involvement determined by level of intoxication	0.638	0.362
R29.4 Clicking hip	0.637	0.363
R29.3 Abnormal posture	0.637	0.363
R29.2 Abnormal reflex	0.637	0.363
R29.1 Meningismus	0.637	0.363
R29.0 Tetany	0.637	0.363
S10 Superficial injury of neck	0.636	0.364
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.636	0.364
B91 Sequelae of poliomyelitis	0.636	0.364
J17.2 Pneumonia in mycoses	0.635	0.364
M41.5 Other secondary scoliosis	0.635	0.365
M41.4 Neuromuscular scoliosis	0.635	0.365
M41.3 Thoracogenic scoliosis	0.635	0.365
M41.2 Other idiopathic scoliosis	0.635	0.365
M41.1 Juvenile idiopathic scoliosis	0.635	0.365
M41.0 Infantile idiopathic scoliosis	0.635	0.365
I08.0 Disorders of both mitral and aortic valves	0.635	0.365
R25.0 Abnormal head movements	0.634	0.365
M87.2 Osteonecrosis due to previous trauma	0.634	0.366
I97.2 Postmastectomy lymphoedema syndrome	0.633	0.367
E66.1 Drug-induced obesity	0.633	0.367
E20 Hypoparathyroidism	0.632	0.368
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.632	0.368
M06.37 Rheumatoid nodule (Ankle and foot)	0.632	0.368
I45.1 Other and unspecified right bundle-branch block	0.632	0.368
M35.7 Hypermobility syndrome	0.632	0.368
Z36.0 Antenatal screening for chromosomal anomalies	0.631	0.369
R26.3 Immobility	0.631	0.369
Y35-Y36 Legal intervention and operations of war	0.630	0.370
Y10-Y34 Event of undetermined intent	0.630	0.370
X85-X99 Assault	0.630	0.370
X30-X39 Exposure to forces of nature	0.630	0.370
X00-X09 Exposure to smoke, fire and flames	0.630	0.370
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.630	0.370
W75-W84 Other accidental threats to breathing	0.630	0.370
W65-W74 Accidental drowning and submersion	0.630	0.370
V98-V99 Other and unspecified transport accidents	0.630	0.370
V95-V97 Air and space transport accidents	0.630	0.370
V90-V94 Water transport accidents	0.630	0.370
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.630	0.370
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.630	0.370
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.630	0.370
M22.1 Recurrent subluxation of patella	0.630	0.370
M22.9 Disorder of patella, unspecified	0.630	0.370
M22.0 Recurrent dislocation of patella	0.630	0.370
M81.0 Postmenopausal osteoporosis	0.630	0.370
I07 Rheumatic tricuspid valve diseases	0.630	0.370
M07.3 Other psoriatic arthropathies	0.629	0.371
M24.09 Loose body in joint (Site unspecified)	0.629	0.371
M24.08 Loose body in joint (Other)	0.629	0.371
M24.06 Loose body in joint-Lower leg	0.629	0.371
M24.05 Loose body in joint (Pelvic region and thigh)	0.629	0.371
M24.04 Loose body in joint (Hand)	0.629	0.371
M24.03 Loose body in joint (Forearm)	0.629	0.371
M24.00 Loose body in joint (Multiple sites)	0.629	0.371
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.629	0.371
M87.98 Osteonecrosis, unspecified (Other)	0.629	0.371
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.629	0.371
M87.96 Osteonecrosis, unspecified (Lower leg)	0.629	0.371
M87.94 Osteonecrosis, unspecified (Hand)	0.629	0.371
M87.93 Osteonecrosis, unspecified (Forearm)	0.629	0.371
M87.92 Osteonecrosis, unspecified (Upper arm)	0.629	0.371
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.629	0.371
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.629	0.371
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.628	0.372
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.628	0.372
J46 Status asthmaticus	0.627	0.373
M81.40 Drug-induced osteoporosis (Multiple sites)	0.627	0.373
M85.8 Other specified disorders of bone density and structure	0.626	0.374
S99 Other and unspecified injuries of ankle and foot	0.626	0.374
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.626	0.374
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.624	0.376
E24 Cushing's syndrome	0.624	0.376
I00-I02 Acute rheumatic fever	0.623	0.377
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.623	0.377
M10.94 Gout, unspecified (Hand)	0.623	0.377
M84 Disorders of continuity of bone	0.622	0.378
H74.4 Polyp of middle ear	0.622	0.378
I98 Other disorders of circulatory system in diseases classified elsewhere	0.622	0.378
R49.8 Other and unspecified voice disturbances	0.621	0.379
S00.9 Superficial injury of head, part unspecified	0.621	0.379
M24.51 Contracture of joint (Shoulder region)	0.621	0.379
I34 Nonrheumatic mitral valve disorders	0.621	0.379
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.620	0.380
V80-V89 Other land transport accidents	0.619	0.381
S32.0 Fracture of lumbar vertebra	0.618	0.382
M10.4 Other secondary gout	0.617	0.383
M10.3 Gout due to impairment of renal function	0.617	0.383
M10.2 Drug-induced gout	0.617	0.383
M10.1 Lead-induced gout	0.617	0.383
M10.0 Idiopathic gout	0.617	0.383
M96.0 Pseudarthrosis after fusion or arthrodesis	0.617	0.383
X58-X59 Accidental exposure to other and unspecified factors	0.616	0.384
M92 Other juvenile osteochondrosis	0.616	0.384
M91 Juvenile osteochondrosis of hip and pelvis	0.616	0.384
J15.9 Bacterial pneumonia, unspecified	0.616	0.384
J15.8 Other bacterial pneumonia	0.616	0.384
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.616	0.384
J15.5 Pneumonia due to Escherichia coli	0.616	0.384
J15.3 Pneumonia due to streptococcus, group B	0.616	0.384
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.615	0.385
J22 Unspecified acute lower respiratory infection	0.615	0.385
S27 Injury of other and unspecified intrathoracic organs	0.615	0.385
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.614	0.386
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.613	0.387
Z58 Problems related to physical environment	0.613	0.387
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.613	0.387
H65.3 Chronic mucoid otitis media	0.613	0.387
E21.3 Hyperparathyroidism, unspecified	0.612	0.388
M22.3 Other derangements of patella	0.612	0.388
M24.54 Contracture of joint (Hand)	0.611	0.388
A44 Bartonellosis	0.611	0.389
A43 Nocardiosis	0.611	0.389
A42 Actinomycosis	0.611	0.389
A37 Whooping cough	0.611	0.389
A36 Diphtheria	0.611	0.389
A32 Listeriosis	0.611	0.389
A31 Infection due to other mycobacteria	0.611	0.389
A30 Leprosy [Hansen's disease]	0.611	0.389

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations