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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72655627
log Bayes Factor = 15.4721
Chromosome 8   position 55,287,974  (GRCh37) Explore rs72655627 on Ensembl!
Variant rs72655627 is part of Cluster X0197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
S50-S59 Injuries to the elbow and forearm
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.996 0.004 0.000
S52 Fracture of forearm
0.994 0.006 0.000
S52.5 Fracture of lower end of radius
0.993 0.007 0.000
S52.50 Fracture of lower end of radius (closed)
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
C25 Malignant neoplasm of pancreas
0.982 0.018 0.000
B95-B98 Bacterial, viral and other infectious agents
0.979 0.021 0.000
C18 Malignant neoplasm of colon
0.975 0.025 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.974 0.026 0.000
A30-A49 Other bacterial diseases
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
S40-S49 Injuries to the shoulder and upper arm
0.962 0.038 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.961 0.039 0.000
B25-B34 Other viral diseases
0.958 0.042 0.000
D50-D53 Nutritional anaemias
0.956 0.044 0.000
J00-J06 Acute upper respiratory infections
0.950 0.050 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.948 0.052 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.946 0.054 0.000
C25.0 Head of pancreas
0.942 0.058 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.936 0.064 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.936 0.064 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.935 0.065 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.932 0.068 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.930 0.070 0.000
D50 Iron deficiency anaemia
0.927 0.073 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.924 0.076 0.000
R07 Pain in throat and chest
0.924 0.076 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.924 0.076 0.000
C18.9 Colon, unspecified
0.923 0.077 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.923 0.077 0.000
B34 Viral infection of unspecified site
0.922 0.078 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.922 0.078 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.921 0.079 0.000
R10.1 Pain localised to upper abdomen
0.919 0.081 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.916 0.084 0.000
R10 Abdominal and pelvic pain
0.916 0.084 0.000
J90-J94 Other diseases of pleura
0.910 0.090 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.910 0.090 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.910 0.090 0.000
S80-S89 Injuries to the knee and lower leg
0.909 0.091 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.909 0.091 0.000
C25.9 Pancreas, unspecified
0.908 0.092 0.000
D50.8 Other iron deficiency anaemias
0.903 0.097 0.000
A41 Other septicaemia
0.902 0.098 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.897 0.103 0.000
D60-D64 Aplastic and other anaemias
0.892 0.108 0.000
S43.0 Dislocation of shoulder joint
0.890 0.110 0.000
B34.9 Viral infection, unspecified
0.889 0.111 0.000
R94 Abnormal results of function studies
0.888 0.112 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.885 0.115 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.884 0.116 0.000
J06.9 Acute upper respiratory infection, unspecified
0.881 0.119 0.000
R05 Cough
0.877 0.123 0.000
F20 Schizophrenia
0.877 0.123 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.875 0.125 0.000
J09-J18 Influenza and pneumonia
0.872 0.128 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.871 0.129 0.000
C91 Lymphoid leukaemia
0.870 0.130 0.000
Chapter VII Diseases of the eye and adnexa
0.864 0.136 0.000
R06 Abnormalities of breathing
0.860 0.140 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.858 0.142 0.000
S10-S19 Injuries to the neck
0.858 0.142 0.000
R94.5 Abnormal results of liver function studies
0.858 0.142 0.000
T66-T78 Other and unspecified effects of external causes
0.857 0.143 0.000
S00-S09 Injuries to the head
0.855 0.145 0.000
R25 Abnormal involuntary movements
0.854 0.146 0.000
T51 Toxic effect of alcohol
0.854 0.146 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.853 0.147 0.000
Y57 Other and unspecified drugs and medicaments
0.853 0.147 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.852 0.148 0.000
Chapter VI Diseases of the nervous system
0.850 0.150 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.849 0.151 0.000
R17 Unspecified jaundice
0.847 0.153 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.846 0.154 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.844 0.156 0.000
J90 Pleural effusion, not elsewhere classified
0.842 0.158 0.000
G35 Multiple sclerosis
0.841 0.159 0.000
C77.2 Intra-abdominal lymph nodes
0.840 0.160 0.000
C92 Myeloid leukaemia
0.838 0.162 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.835 0.164 0.000
Chapter XXII Codes for special purposes
0.835 0.165 0.000
Y44 Agents primarily affecting blood constituents
0.834 0.166 0.000
T79-T79 Certain early complications of trauma
0.834 0.166 0.000
A49 Bacterial infection of unspecified site
0.830 0.170 0.000
J00 Acute nasopharyngitis [common cold]
0.828 0.172 0.000
R07.3 Other chest pain
0.827 0.173 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.827 0.173 0.000
C90.0 Multiple myeloma
0.826 0.174 0.000
W50-W64 Exposure to animate mechanical forces
0.825 0.175 0.000
R07.2 Precordial pain
0.823 0.177 0.000
H55-H59 Other disorders of eye and adnexa
0.821 0.178 0.000
R06.0 Dyspnoea
0.820 0.180 0.000
R00 Abnormalities of heart beat
0.818 0.182 0.000
X50-X57 Overexertion, travel and privation
0.816 0.184 0.000
M20-M25 Other joint disorders
0.816 0.184 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.814 0.186 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.810 0.189 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.806 0.194 0.000
J11 Influenza, virus not identified
0.805 0.195 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.805 0.195 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.804 0.196 0.000
C18.6 Descending colon
0.803 0.197 0.000
S53.3 Traumatic rupture of ulnar collateral ligament
0.803 0.197 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.802 0.198 0.000
J93 Pneumothorax
0.801 0.199 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.800 0.200 0.000
D68 Other coagulation defects
0.800 0.200 0.000
R25.2 Cramp and spasm
0.799 0.201 0.000
C18.4 Transverse colon
0.798 0.202 0.000
S80 Superficial injury of lower leg
0.797 0.203 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.796 0.204 0.000
C77.3 Axillary and upper limb lymph nodes
0.796 0.204 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.796 0.204 0.000
T51.0 Ethanol
0.795 0.205 0.000
Q80-Q89 Other congenital malformations
0.793 0.207 0.000
A41.9 Septicaemia, unspecified
0.793 0.207 0.000
Chapter IX Diseases of the circulatory system
0.792 0.208 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.792 0.208 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.791 0.209 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.791 0.209 0.000
D61 Other aplastic anaemias
0.790 0.210 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.790 0.210 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.789 0.211 0.000
S40 Superficial injury of shoulder and upper arm
0.789 0.211 0.000
C85.1 B-cell lymphoma, unspecified
0.787 0.213 0.000
D50.9 Iron deficiency anaemia, unspecified
0.786 0.214 0.000
F20.0 Paranoid schizophrenia
0.785 0.215 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.784 0.216 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.784 0.216 0.000
T91 Sequelae of injuries of neck and trunk
0.781 0.219 0.000
C16 Malignant neoplasm of stomach
0.781 0.219 0.000
C18.7 Sigmoid colon
0.781 0.219 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.780 0.220 0.000
R07.4 Chest pain, unspecified
0.779 0.221 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.778 0.222 0.000
Y40 Systemic antibiotics
0.775 0.225 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.774 0.226 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.774 0.226 0.000
Y43 Primarily systemic agents
0.773 0.227 0.000
J20-J22 Other acute lower respiratory infections
0.772 0.228 0.000
C88 Malignant immunoproliferative diseases
0.771 0.229 0.000
M23 Internal derangement of knee
0.771 0.229 0.000
R18 Ascites
0.770 0.230 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.768 0.232 0.000
C91.1 Chronic lymphocytic leukaemia
0.767 0.233 0.000
C17 Malignant neoplasm of small intestine
0.767 0.233 0.000
C18.0 Caecum
0.766 0.233 0.000
R10.2 Pelvic and perineal pain
0.764 0.236 0.000
B65-B83 Helminthiases
0.764 0.236 0.000
F20.9 Schizophrenia, unspecified
0.762 0.238 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.762 0.238 0.000
T90 Sequelae of injuries of head
0.762 0.238 0.000
L20-L30 Dermatitis and eczema
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
F99-F99 Unspecified mental disorder
0.760 0.240 0.000
A46 Erysipelas
0.759 0.241 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.757 0.243 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.757 0.243 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.757 0.243 0.000
R47-R49 Symptoms and signs involving speech and voice
0.756 0.244 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.755 0.245 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.755 0.245 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
D52 Folate deficiency anaemia
0.754 0.246 0.000
C64-C68 Malignant neoplasms of urinary tract
0.754 0.246 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.753 0.247 0.000
F29 Unspecified nonorganic psychosis
0.753 0.247 0.000
I27 Other pulmonary heart diseases
0.752 0.248 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.752 0.248 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.752 0.248 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
C77.1 Intrathoracic lymph nodes
0.751 0.249 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.751 0.249 0.000
M23.3 Other meniscus derangements
0.751 0.249 0.000
T93 Sequelae of injuries of lower limb
0.751 0.249 0.000
T68 Hypothermia
0.749 0.251 0.000
D68.9 Coagulation defect, unspecified
0.749 0.251 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.749 0.251 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.747 0.253 0.000
D55-D59 Haemolytic anaemias
0.747 0.253 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.747 0.253 0.000
C18.5 Splenic flexure
0.747 0.253 0.000
H57 Other disorders of eye and adnexa
0.746 0.254 0.000
B25 Cytomegaloviral disease
0.742 0.258 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.742 0.258 0.000
R01 Cardiac murmurs and other cardiac sounds
0.742 0.258 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.741 0.259 0.000
Y57.9 Drug or medicament, unspecified
0.741 0.259 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.741 0.259 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.740 0.260 0.000
M70-M79 Other soft tissue disorders
0.740 0.260 0.000
Y44.2 Anticoagulants
0.739 0.261 0.000
T86 Failure and rejection of transplanted organs and tissues
0.738 0.262 0.000
S70-S79 Injuries to the hip and thigh
0.738 0.262 0.000
J93.9 Pneumothorax, unspecified
0.737 0.263 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.737 0.263 0.000
A40 Streptococcal septicaemia
0.736 0.264 0.000
D62 Acute posthaemorrhagic anaemia
0.736 0.264 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.734 0.265 0.000
T16 Foreign body in ear
0.734 0.266 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.733 0.267 0.000
T59 Toxic effect of other gases, fumes and vapours
0.733 0.267 0.000
F10.1 Harmful use
0.733 0.267 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.268 0.000
S51 Open wound of forearm
0.731 0.268 0.000
H40-H42 Glaucoma
0.732 0.268 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.731 0.269 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.731 0.269 0.000
R06.4 Hyperventilation
0.728 0.272 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.728 0.272 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.727 0.273 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.726 0.273 0.000
F23 Acute and transient psychotic disorders
0.726 0.274 0.000
C92.0 Acute myeloid leukaemia
0.726 0.274 0.000
R94.4 Abnormal results of kidney function studies
0.725 0.274 0.000
C77.8 Lymph nodes of multiple regions
0.725 0.275 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.725 0.275 0.000
M75 Shoulder lesions
0.725 0.275 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.724 0.276 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.724 0.276 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.721 0.279 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.279 0.000
S81 Open wound of lower leg
0.720 0.279 0.000
S43.1 Dislocation of acromioclavicular joint
0.718 0.282 0.000
Q50-Q56 Congenital malformations of genital organs
0.718 0.282 0.000
D61.9 Aplastic anaemia, unspecified
0.717 0.282 0.000
C90.2 Plasmacytoma, extramedullary
0.717 0.283 0.000
I27.0 Primary pulmonary hypertension
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
S59 Other and unspecified injuries of forearm
0.715 0.285 0.000
S58 Traumatic amputation of forearm
0.715 0.285 0.000
S57 Crushing injury of forearm
0.715 0.285 0.000
S56 Injury of muscle and tendon at forearm level
0.715 0.285 0.000
S55 Injury of blood vessels at forearm level
0.715 0.285 0.000
S54 Injury of nerves at forearm level
0.715 0.285 0.000
S06 Intracranial injury
0.715 0.285 0.000
C23 Malignant neoplasm of gallbladder
0.715 0.285 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
C95 Leukaemia of unspecified cell type
0.714 0.286 0.000
C94 Other leukaemias of specified cell type
0.714 0.286 0.000
C93 Monocytic leukaemia
0.714 0.286 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.286 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.714 0.286 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.714 0.286 0.000
F10.3 Withdrawal state
0.714 0.286 0.000
J03 Acute tonsillitis
0.714 0.286 0.000
B34.8 Other viral infections of unspecified site
0.713 0.287 0.000
S52.9 Fracture of forearm, part unspecified
0.713 0.287 0.000
S52.7 Multiple fractures of forearm
0.713 0.287 0.000
S52.4 Fracture of shafts of both ulna and radius
0.713 0.287 0.000
S52.3 Fracture of shaft of radius
0.713 0.287 0.000
S52.2 Fracture of shaft of ulna
0.713 0.287 0.000
S52.51 Fracture of lower end of radius (open)
0.712 0.288 0.000
F10.0 Acute intoxication
0.710 0.290 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.710 0.290 0.000
I26 Pulmonary embolism
0.710 0.290 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.290 0.000
A49.0 Staphylococcal infection, unspecified
0.709 0.291 0.000
C81 Hodgkin's disease
0.709 0.291 0.000
C21 Malignant neoplasm of anus and anal canal
0.709 0.291 0.000
T58 Toxic effect of carbon monoxide
0.709 0.291 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.709 0.291 0.000
G37 Other demyelinating diseases of central nervous system
0.708 0.292 0.000
S52.8 Fracture of other parts of forearm
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.704 0.295 0.000
C25.8 Overlapping lesion of pancreas
0.704 0.296 0.000
C25.7 Other parts of pancreas
0.704 0.296 0.000
C25.4 Endocrine pancreas
0.704 0.296 0.000
C25.3 Pancreatic duct
0.704 0.296 0.000
C25.2 Tail of pancreas
0.704 0.296 0.000
C25.1 Body of pancreas
0.704 0.296 0.000
S10 Superficial injury of neck
0.704 0.296 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
C50-C50 Malignant neoplasm of breast
0.704 0.296 0.000
S80.9 Superficial injury of lower leg, unspecified
0.703 0.297 0.000
S50 Superficial injury of forearm
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.702 0.298 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.702 0.298 0.000
S89 Other and unspecified injuries of lower leg
0.702 0.298 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.700 0.300 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.700 0.300 0.000
C18.8 Overlapping lesion of colon
0.699 0.301 0.000
C18.3 Hepatic flexure
0.699 0.301 0.000
C18.1 Appendix
0.699 0.301 0.000
S05 Injury of eye and orbit
0.699 0.301 0.000
M24 Other specific joint derangements
0.699 0.301 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.698 0.302 0.000
S52.0 Fracture of upper end of ulna
0.698 0.302 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.697 0.303 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.697 0.303 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.697 0.303 0.000
C77.5 Intrapelvic lymph nodes
0.697 0.303 0.000
X50 Overexertion and strenuous or repetitive movements
0.695 0.305 0.000
Y52 Agents primarily affecting the cardiovascular system
0.694 0.305 0.000
A48 Other bacterial diseases, not elsewhere classified
0.694 0.306 0.000
A44 Bartonellosis
0.694 0.306 0.000
A43 Nocardiosis
0.694 0.306 0.000
A42 Actinomycosis
0.694 0.306 0.000
A39 Meningococcal infection
0.694 0.306 0.000
A37 Whooping cough
0.694 0.306 0.000
A36 Diphtheria
0.694 0.306 0.000
A32 Listeriosis
0.694 0.306 0.000
A31 Infection due to other mycobacteria
0.694 0.306 0.000
A30 Leprosy [Hansen's disease]
0.694 0.306 0.000
A38 Scarlet fever
0.694 0.306 0.000
A35 Other tetanus
0.694 0.306 0.000
A34 Obstetrical tetanus
0.694 0.306 0.000
A33 Tetanus neonatorum
0.694 0.306 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.693 0.307 0.000
C16.9 Stomach, unspecified
0.690 0.310 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.690 0.310 0.000
R00.2 Palpitations
0.690 0.310 0.000
S48 Traumatic amputation of shoulder and upper arm
0.689 0.310 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.689 0.310 0.000
S44 Injury of nerves at shoulder and upper arm level
0.689 0.310 0.000
S41 Open wound of shoulder and upper arm
0.689 0.310 0.000
S47 Crushing injury of shoulder and upper arm
0.689 0.310 0.000
B35-B49 Mycoses
0.689 0.311 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.689 0.311 0.000
I05 Rheumatic mitral valve diseases
0.688 0.312 0.000
M40-M43 Deforming dorsopathies
0.687 0.313 0.000
B33 Other viral diseases, not elsewhere classified
0.687 0.313 0.000
B30 Viral conjunctivitis
0.687 0.313 0.000
B27 Infectious mononucleosis
0.687 0.313 0.000
B26 Mumps
0.687 0.313 0.000
H57.1 Ocular pain
0.686 0.313 0.000
D53 Other nutritional anaemias
0.686 0.314 0.000
T91.1 Sequelae of fracture of spine
0.685 0.315 0.000
M86-M90 Other osteopathies
0.684 0.316 0.000
M75.5 Bursitis of shoulder
0.684 0.316 0.000
F10.4 Withdrawal state with delirium
0.684 0.316 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.683 0.317 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.683 0.317 0.000
S09 Other and unspecified injuries of head
0.682 0.318 0.000
J17 Pneumonia in diseases classified elsewhere
0.682 0.318 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.681 0.319 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.681 0.319 0.000
T85.2 Mechanical complication of intraocular lens
0.680 0.320 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.680 0.320 0.000
C85.0 Lymphosarcoma
0.680 0.320 0.000
S90 Superficial injury of ankle and foot
0.679 0.321 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.679 0.321 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.678 0.322 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.677 0.323 0.000
M20 Acquired deformities of fingers and toes
0.676 0.324 0.000
T92 Sequelae of injuries of upper limb
0.676 0.324 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.675 0.325 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.675 0.325 0.000
T87 Complications peculiar to reattachment and amputation
0.674 0.326 0.000
M75.0 Adhesive capsulitis of shoulder
0.674 0.326 0.000
J60-J70 Lung diseases due to external agents
0.672 0.328 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.672 0.328 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.671 0.328 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.671 0.328 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.671 0.328 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.671 0.328 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.671 0.328 0.000
F11 Mental and behavioural disorders due to use of opioids
0.671 0.328 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.328 0.000
F25 Schizoaffective disorders
0.671 0.329 0.000
F28 Other nonorganic psychotic disorders
0.671 0.329 0.000
F24 Induced delusional disorder
0.671 0.329 0.000
F21 Schizotypal disorder
0.671 0.329 0.000
E20-E35 Disorders of other endocrine glands
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T36 Poisoning by systemic antibiotics
0.670 0.330 0.000
S83.2 Tear of meniscus, current
0.670 0.330 0.000
M91-M94 Chondropathies
0.669 0.331 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.669 0.331 0.000
A80-A89 Viral infections of the central nervous system
0.669 0.331 0.000
R26 Abnormalities of gait and mobility
0.668 0.332 0.000
Y57.8 Other drugs and medicaments
0.668 0.332 0.000
L60-L75 Disorders of skin appendages
0.668 0.332 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.667 0.333 0.000
F60-F69 Disorders of adult personality and behaviour
0.667 0.333 0.000
T65 Toxic effect of other and unspecified substances
0.667 0.333 0.000
T62 Toxic effect of other noxious substances eaten as food
0.667 0.333 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.667 0.333 0.000
T60 Toxic effect of pesticides
0.667 0.333 0.000
T57 Toxic effect of other inorganic substances
0.667 0.333 0.000
T56 Toxic effect of metals
0.667 0.333 0.000
T54 Toxic effect of corrosive substances
0.667 0.333 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.667 0.333 0.000
T52 Toxic effect of organic solvents
0.667 0.333 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.667 0.333 0.000
T55 Toxic effect of soaps and detergents
0.667 0.333 0.000
T42.4 Benzodiazepines
0.666 0.334 0.000
D50.1 Sideropenic dysphagia
0.664 0.335 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.664 0.336 0.000
R49 Voice disturbances
0.664 0.336 0.000
D51 Vitamin B12 deficiency anaemia
0.664 0.336 0.000
E65-E68 Obesity and other hyperalimentation
0.664 0.336 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.663 0.337 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.663 0.337 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.663 0.337 0.000
S43.4 Sprain and strain of shoulder joint
0.663 0.337 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.663 0.337 0.000
S43.2 Dislocation of sternoclavicular joint
0.663 0.337 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.663 0.337 0.000
J94 Other pleural conditions
0.662 0.338 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.662 0.338 0.000
Q35-Q37 Cleft lip and cleft palate
0.662 0.338 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.662 0.338 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.338 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.338 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.338 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.338 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.338 0.000
T43.2 Other and unspecified antidepressants
0.662 0.338 0.000
B34.4 Papovirus infection, unspecified
0.661 0.339 0.000
B34.3 Parvovirus infection, unspecified
0.661 0.339 0.000
B34.2 Coronavirus infection, unspecified
0.661 0.339 0.000
B34.1 Enterovirus infection, unspecified
0.661 0.339 0.000
B34.0 Adenovirus infection, unspecified
0.661 0.339 0.000
C77.9 Lymph node, unspecified
0.661 0.339 0.000
M65-M68 Disorders of synovium and tendon
0.661 0.339 0.000
A49.8 Other bacterial infections of unspecified site
0.661 0.339 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.660 0.339 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.660 0.340 0.000
R00.0 Tachycardia, unspecified
0.660 0.340 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.660 0.340 0.000
J01 Acute sinusitis
0.659 0.340 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.659 0.341 0.000
D63.0 Anaemia in neoplastic disease
0.659 0.341 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
Y43.3 Other antineoplastic drugs
0.658 0.342 0.000
F80-F89 Disorders of psychological development
0.658 0.342 0.000
I30-I52 Other forms of heart disease
0.658 0.342 0.000
T17 Foreign body in respiratory tract
0.658 0.342 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.657 0.343 0.000
M21 Other acquired deformities of limbs
0.656 0.344 0.000
T88.4 Failed or difficult intubation
0.655 0.344 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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