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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77173849
log Bayes Factor = 16.2623
Chromosome 8   position 47,021,723  (GRCh37) Explore rs77173849 on Ensembl!
Variant rs77173849 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
E70-E90 Metabolic disorders
0.984 0.016 0.000
E11 Non-insulin-dependent diabetes mellitus
0.983 0.017 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.983 0.017 0.000
C60-C63 Malignant neoplasms of male genital organs
0.981 0.019 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.980 0.020 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.979 0.021 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
I60-I69 Cerebrovascular diseases
0.975 0.025 0.000
J90-J94 Other diseases of pleura
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.972 0.028 0.000
C61 Malignant neoplasm of prostate
0.970 0.030 0.000
B35-B49 Mycoses
0.969 0.031 0.000
Z51 Other medical care
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
Z51.5 Palliative care
0.960 0.040 0.000
B37 Candidiasis
0.957 0.043 0.000
I26 Pulmonary embolism
0.955 0.045 0.000
E11.9 Without complications
0.955 0.045 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.948 0.052 0.000
J90 Pleural effusion, not elsewhere classified
0.938 0.062 0.000
D10-D36 Benign neoplasms
0.937 0.063 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.937 0.063 0.000
J40-J47 Chronic lower respiratory diseases
0.933 0.067 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.931 0.069 0.000
R30-R39 Symptoms and signs involving the urinary system
0.930 0.070 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.929 0.071 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.925 0.075 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.923 0.077 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.923 0.077 0.000
M45-M49 Spondylopathies
0.919 0.081 0.000
D22 Melanocytic naevi
0.918 0.082 0.000
B37.0 Candidal stomatitis
0.918 0.082 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.917 0.083 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.917 0.083 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.911 0.089 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.910 0.090 0.000
R39 Other symptoms and signs involving the urinary system
0.909 0.091 0.000
I10-I15 Hypertensive diseases
0.907 0.093 0.000
Z51.8 Other specified medical care
0.906 0.094 0.000
J44 Other chronic obstructive pulmonary disease
0.906 0.094 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.902 0.098 0.000
M05-M14 Inflammatory polyarthropathies
0.901 0.099 0.000
A30-A49 Other bacterial diseases
0.901 0.099 0.000
Z22 Carrier of infectious disease
0.899 0.101 0.000
Z50 Care involving use of rehabilitation procedures
0.895 0.105 0.000
O60-O75 Complications of labour and delivery
0.895 0.105 0.000
M20-M25 Other joint disorders
0.894 0.106 0.000
C79 Secondary malignant neoplasm of other sites
0.891 0.109 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.886 0.114 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.885 0.115 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.885 0.115 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.880 0.120 0.000
R13 Dysphagia
0.879 0.121 0.000
E83 Disorders of mineral metabolism
0.879 0.121 0.000
B37.3 Candidiasis of vulva and vagina
0.879 0.121 0.000
Z22.3 Carrier of other specified bacterial diseases
0.878 0.122 0.000
J95-J99 Other diseases of the respiratory system
0.876 0.124 0.000
D12.8 Rectum
0.875 0.125 0.000
D12.6 Colon, unspecified
0.875 0.125 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.872 0.128 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.871 0.129 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.870 0.130 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.869 0.131 0.000
I12 Hypertensive renal disease
0.869 0.131 0.000
E65-E68 Obesity and other hyperalimentation
0.868 0.132 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.868 0.132 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.866 0.134 0.000
E11.3 With ophthalmic complications
0.862 0.138 0.000
C64-C68 Malignant neoplasms of urinary tract
0.861 0.139 0.000
M50-M54 Other dorsopathies
0.857 0.143 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.853 0.147 0.000
M20 Acquired deformities of fingers and toes
0.851 0.149 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.850 0.150 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.845 0.155 0.000
M48 Other spondylopathies
0.844 0.156 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.844 0.156 0.000
I12.0 Hypertensive renal disease with renal failure
0.842 0.158 0.000
R12 Heartburn
0.835 0.165 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.833 0.167 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.831 0.169 0.000
E11.4 With neurological complications
0.831 0.169 0.000
I30-I52 Other forms of heart disease
0.830 0.170 0.000
I27 Other pulmonary heart diseases
0.829 0.171 0.000
O20 Haemorrhage in early pregnancy
0.829 0.171 0.000
T66-T78 Other and unspecified effects of external causes
0.828 0.172 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.825 0.174 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.823 0.177 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.822 0.178 0.000
D68 Other coagulation defects
0.821 0.179 0.000
J94 Other pleural conditions
0.817 0.183 0.000
J60-J70 Lung diseases due to external agents
0.817 0.183 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.812 0.188 0.000
M20.4 Other hammer toe(s) (acquired)
0.812 0.188 0.000
C67 Malignant neoplasm of bladder
0.812 0.188 0.000
I63 Cerebral infarction
0.809 0.191 0.000
R14 Flatulence and related conditions
0.809 0.191 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.809 0.191 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.808 0.192 0.000
L60-L75 Disorders of skin appendages
0.808 0.192 0.000
A49 Bacterial infection of unspecified site
0.808 0.192 0.000
E83.5 Disorders of calcium metabolism
0.807 0.193 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.804 0.196 0.000
E16 Other disorders of pancreatic internal secretion
0.803 0.197 0.000
M06 Other rheumatoid arthritis
0.803 0.197 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
E87.3 Alkalosis
0.801 0.199 0.000
L82 Seborrhoeic keratosis
0.798 0.202 0.000
J91 Pleural effusion in conditions classified elsewhere
0.798 0.202 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.798 0.202 0.000
D22.4 Melanocytic naevi of scalp and neck
0.795 0.205 0.000
Z50.1 Other physical therapy
0.795 0.205 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.793 0.207 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.792 0.208 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.792 0.208 0.000
M48.0 Spinal stenosis
0.791 0.209 0.000
J20-J22 Other acute lower respiratory infections
0.790 0.210 0.000
L84 Corns and callosities
0.788 0.212 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.787 0.213 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.786 0.214 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.785 0.215 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
M20.5 Other deformities of toe(s) (acquired)
0.784 0.216 0.000
Z51.2 Other chemotherapy
0.783 0.217 0.000
D12.4 Descending colon
0.782 0.218 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.782 0.218 0.000
F10.1 Harmful use
0.782 0.218 0.000
J09-J18 Influenza and pneumonia
0.781 0.219 0.000
F60-F69 Disorders of adult personality and behaviour
0.780 0.220 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.780 0.220 0.000
J98 Other respiratory disorders
0.779 0.221 0.000
E50-E64 Other nutritional deficiencies
0.778 0.222 0.000
M70-M79 Other soft tissue disorders
0.776 0.224 0.000
E20-E35 Disorders of other endocrine glands
0.774 0.226 0.000
Z49 Care involving dialysis
0.774 0.226 0.000
E66 Obesity
0.773 0.227 0.000
J46 Status asthmaticus
0.772 0.228 0.000
C77.0 Lymph nodes of head, face and neck
0.772 0.228 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.771 0.229 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.771 0.229 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.768 0.232 0.000
L50-L54 Urticaria and erythema
0.767 0.233 0.000
O20.0 Threatened abortion
0.767 0.233 0.000
M13 Other arthritis
0.764 0.236 0.000
Z40 Prophylactic surgery
0.763 0.237 0.000
Z44 Fitting and adjustment of external prosthetic device
0.763 0.237 0.000
E11.5 With peripheral circulatory complications
0.761 0.239 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.761 0.239 0.000
E86 Volume depletion
0.760 0.240 0.000
Z52 Donors of organs and tissues
0.759 0.241 0.000
S70-S79 Injuries to the hip and thigh
0.758 0.242 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.758 0.242 0.000
E10 Insulin-dependent diabetes mellitus
0.757 0.243 0.000
Chapter XX External causes of morbidity and mortality
0.757 0.243 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.756 0.244 0.000
I60 Subarachnoid haemorrhage
0.756 0.244 0.000
E40-E46 Malnutrition
0.755 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
D22.0 Melanocytic naevi of lip
0.755 0.245 0.000
L89 Decubitus ulcer
0.755 0.245 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.754 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.753 0.247 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.752 0.248 0.000
M65-M68 Disorders of synovium and tendon
0.752 0.248 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.752 0.248 0.000
M40-M43 Deforming dorsopathies
0.751 0.249 0.000
A80-A89 Viral infections of the central nervous system
0.751 0.249 0.000
E87.7 Fluid overload
0.750 0.249 0.000
L90 Atrophic disorders of skin
0.747 0.253 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.747 0.253 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.747 0.253 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.746 0.254 0.000
C01 Malignant neoplasm of base of tongue
0.746 0.254 0.000
E16.2 Hypoglycaemia, unspecified
0.745 0.255 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.742 0.258 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.742 0.258 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.742 0.258 0.000
C77.5 Intrapelvic lymph nodes
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.258 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.741 0.259 0.000
F30-F39 Mood [affective] disorders
0.739 0.261 0.000
B44 Aspergillosis
0.739 0.261 0.000
E87.6 Hypokalaemia
0.738 0.262 0.000
B37.8 Candidiasis of other sites
0.737 0.263 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.737 0.263 0.000
I69 Sequelae of cerebrovascular disease
0.736 0.264 0.000
S60-S69 Injuries to the wrist and hand
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.264 0.000
A41 Other septicaemia
0.735 0.265 0.000
D10 Benign neoplasm of mouth and pharynx
0.735 0.265 0.000
F10.3 Withdrawal state
0.733 0.267 0.000
M06.9 Rheumatoid arthritis, unspecified
0.732 0.268 0.000
E87.5 Hyperkalaemia
0.731 0.268 0.000
E78.5 Hyperlipidaemia, unspecified
0.731 0.269 0.000
I15 Secondary hypertension
0.728 0.272 0.000
R80 Isolated proteinuria
0.728 0.272 0.000
B15-B19 Viral hepatitis
0.728 0.272 0.000
I77 Other disorders of arteries and arterioles
0.728 0.272 0.000
D47.1 Chronic myeloproliferative disease
0.727 0.273 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.727 0.273 0.000
M51 Other intervertebral disk disorders
0.725 0.275 0.000
M45 Ankylosing spondylitis
0.725 0.275 0.000
E83.4 Disorders of magnesium metabolism
0.724 0.276 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.723 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
D46 Myelodysplastic syndromes
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.722 0.278 0.000
I46 Cardiac arrest
0.721 0.278 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.721 0.279 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
M30 Polyarteritis nodosa and related conditions
0.720 0.280 0.000
E66.8 Other obesity
0.720 0.280 0.000
I67 Other cerebrovascular diseases
0.720 0.280 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.719 0.281 0.000
Z45 Adjustment and management of implanted device
0.718 0.281 0.000
C67.9 Bladder, unspecified
0.718 0.282 0.000
F80-F89 Disorders of psychological development
0.718 0.282 0.000
Z50.8 Care involving use of rehabilitation procedures
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
R81 Glycosuria
0.716 0.284 0.000
R31 Unspecified haematuria
0.715 0.285 0.000
D45 Polycythaemia vera
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
E11.2 With renal complications
0.712 0.288 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.711 0.289 0.000
E13 Other specified diabetes mellitus
0.710 0.289 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.289 0.000
R41.0 Disorientation, unspecified
0.710 0.290 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.709 0.291 0.000
E87.2 Acidosis
0.709 0.291 0.000
R25 Abnormal involuntary movements
0.708 0.291 0.000
A49.8 Other bacterial infections of unspecified site
0.708 0.292 0.000
M47 Spondylosis
0.707 0.293 0.000
D12.2 Ascending colon
0.707 0.293 0.000
C77.1 Intrathoracic lymph nodes
0.707 0.293 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
E14 Unspecified diabetes mellitus
0.706 0.294 0.000
E85 Amyloidosis
0.706 0.294 0.000
E84 Cystic fibrosis
0.706 0.294 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.294 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.294 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E73 Lactose intolerance
0.706 0.294 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.294 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.294 0.000
J94.8 Other specified pleural conditions
0.705 0.294 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.705 0.295 0.000
E11.8 With unspecified complications
0.705 0.295 0.000
E11.7 With multiple complications
0.705 0.295 0.000
E11.6 With other specified complications
0.705 0.295 0.000
E11.1 With ketoacidosis
0.705 0.295 0.000
E11.0 With coma
0.705 0.295 0.000
M48.06 Spinal stenosis (Lumbar region)
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.705 0.295 0.000
I05-I09 Chronic rheumatic heart diseases
0.705 0.295 0.000
D68.8 Other specified coagulation defects
0.705 0.295 0.000
I62 Other nontraumatic intracranial haemorrhage
0.704 0.296 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.704 0.296 0.000
C60 Malignant neoplasm of penis
0.704 0.296 0.000
I28 Other diseases of pulmonary vessels
0.703 0.297 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
T33-T35 Frostbite
0.702 0.298 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.702 0.298 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.702 0.298 0.000
T00-T07 Injuries involving multiple body regions
0.702 0.298 0.000
S10-S19 Injuries to the neck
0.702 0.298 0.000
J93 Pneumothorax
0.701 0.298 0.000
L93 Lupus erythematosus
0.701 0.299 0.000
F99-F99 Unspecified mental disorder
0.700 0.300 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.700 0.300 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.699 0.300 0.000
R42 Dizziness and giddiness
0.699 0.301 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.301 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.301 0.000
D55-D59 Haemolytic anaemias
0.697 0.303 0.000
Z54 Convalescence
0.697 0.303 0.000
Z42 Follow-up care involving plastic surgery
0.696 0.304 0.000
T68 Hypothermia
0.696 0.304 0.000
C77.2 Intra-abdominal lymph nodes
0.695 0.305 0.000
B48 Other mycoses, not elsewhere classified
0.695 0.305 0.000
B47 Mycetoma
0.695 0.305 0.000
B46 Zygomycosis
0.695 0.305 0.000
B45 Cryptococcosis
0.695 0.305 0.000
B43 Chromomycosis and phaeomycotic abscess
0.695 0.305 0.000
B42 Sporotrichosis
0.695 0.305 0.000
B41 Paracoccidioidomycosis
0.695 0.305 0.000
B40 Blastomycosis
0.695 0.305 0.000
B39 Histoplasmosis
0.695 0.305 0.000
B38 Coccidioidomycosis
0.695 0.305 0.000
B36 Other superficial mycoses
0.695 0.305 0.000
B35 Dermatophytosis
0.695 0.305 0.000
B49 Unspecified mycosis
0.695 0.305 0.000
Z51.9 Medical care, unspecified
0.695 0.305 0.000
Z51.6 Desensitisation to allergens
0.695 0.305 0.000
S40-S49 Injuries to the shoulder and upper arm
0.695 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.695 0.305 0.000
F70-F79 Mental retardation
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
D69 Purpura and other haemorrhagic conditions
0.694 0.306 0.000
J00-J06 Acute upper respiratory infections
0.693 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.693 0.307 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.692 0.308 0.000
D80-D89 Certain disorders involving the immune mechanism
0.690 0.310 0.000
O73 Retained placenta and membranes, without haemorrhage
0.690 0.310 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
M80-M85 Disorders of bone density and structure
0.689 0.311 0.000
I63.9 Cerebral infarction, unspecified
0.687 0.313 0.000
B37.9 Candidiasis, unspecified
0.687 0.313 0.000
B37.7 Candidal septicaemia
0.686 0.314 0.000
B37.6 Candidal endocarditis
0.686 0.314 0.000
B37.5 Candidal meningitis
0.686 0.314 0.000
B37.4 Candidiasis of other urogenital sites
0.686 0.314 0.000
B37.2 Candidiasis of skin and nail
0.686 0.314 0.000
B37.1 Pulmonary candidiasis
0.686 0.314 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.686 0.314 0.000
I27.2 Other secondary pulmonary hypertension
0.685 0.315 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.685 0.315 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.684 0.316 0.000
C77.4 Inguinal and lower limb lymph nodes
0.684 0.316 0.000
C67.2 Lateral wall of bladder
0.684 0.316 0.000
M22 Disorders of patella
0.684 0.316 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.684 0.316 0.000
M48.09 Spinal stenosis (Site unspecified)
0.684 0.316 0.000
E87.0 Hyperosmolality and hypernatraemia
0.683 0.317 0.000
M07 Psoriatic and enteropathic arthropathies
0.682 0.318 0.000
J40 Bronchitis, not specified as acute or chronic
0.680 0.320 0.000
E78.2 Mixed hyperlipidaemia
0.680 0.320 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.680 0.320 0.000
I50 Heart failure
0.679 0.321 0.000
R79 Other abnormal findings of blood chemistry
0.678 0.322 0.000
I47 Paroxysmal tachycardia
0.678 0.322 0.000
O21 Excessive vomiting in pregnancy
0.678 0.322 0.000
O26.8 Other specified pregnancy-related conditions
0.678 0.322 0.000
Z60 Problems related to social environment
0.677 0.323 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.676 0.323 0.000
D22.5 Melanocytic naevi of trunk
0.675 0.325 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.675 0.325 0.000
C92 Myeloid leukaemia
0.675 0.325 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.674 0.326 0.000
I72 Other aneurysm
0.674 0.326 0.000
D68.6 Other Thrombophilia
0.674 0.326 0.000
D31 Benign neoplasm of eye and adnexa
0.672 0.328 0.000
D30 Benign neoplasm of urinary organs
0.672 0.328 0.000
D29 Benign neoplasm of male genital organs
0.672 0.328 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.672 0.328 0.000
D26 Other benign neoplasms of uterus
0.672 0.328 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.672 0.328 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.672 0.328 0.000
D19 Benign neoplasm of mesothelial tissue
0.672 0.328 0.000
D16 Benign neoplasm of bone and articular cartilage
0.672 0.328 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.672 0.328 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.672 0.328 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.672 0.328 0.000
L73 Other follicular disorders
0.670 0.330 0.000
L85 Other epidermal thickening
0.670 0.330 0.000
J41 Simple and mucopurulent chronic bronchitis
0.669 0.331 0.000
M34 Systemic sclerosis
0.668 0.332 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.668 0.332 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.668 0.332 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.668 0.332 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.668 0.332 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.668 0.332 0.000
F20 Schizophrenia
0.667 0.333 0.000
Z41 Procedures for purposes other than remedying health state
0.667 0.333 0.000
R36 Urethral discharge
0.667 0.333 0.000
R34 Anuria and oliguria
0.667 0.333 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.667 0.333 0.000
D68.9 Coagulation defect, unspecified
0.667 0.333 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.666 0.334 0.000
Z28 Immunisation not carried out
0.666 0.334 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.666 0.334 0.000
Z26 Need for immunisation against other single infectious diseases
0.666 0.334 0.000
Z25 Need for immunisation against other single viral diseases
0.666 0.334 0.000
Z24 Need for immunisation against certain single viral diseases
0.666 0.334 0.000
Z23 Need for immunisation against single bacterial diseases
0.666 0.334 0.000
Z20 Contact with and exposure to communicable diseases
0.666 0.334 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
M13.9 Arthritis, unspecified
0.665 0.335 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.665 0.335 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.664 0.335 0.000
R47-R49 Symptoms and signs involving speech and voice
0.664 0.336 0.000
R16.1 Splenomegaly, not elsewhere classified
0.664 0.336 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.663 0.337 0.000
E87.4 Mixed disorder of acid-base balance
0.663 0.337 0.000
D12.9 Anus and anal canal
0.662 0.338 0.000
D12.1 Appendix
0.662 0.338 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.661 0.339 0.000
D68.2 Hereditary deficiency of other clotting factors
0.660 0.340 0.000
I78 Diseases of capillaries
0.660 0.340 0.000
M49 Spondylopathies in diseases classified elsewhere
0.659 0.341 0.000
R15 Faecal incontinence
0.658 0.341 0.000
D22.9 Melanocytic naevi, unspecified
0.658 0.342 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.658 0.342 0.000
C62 Malignant neoplasm of testis
0.658 0.342 0.000
J47 Bronchiectasis
0.658 0.342 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.658 0.342 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.657 0.342 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.657 0.342 0.000
L94 Other localised connective tissue disorders
0.657 0.342 0.000
L87 Transepidermal elimination disorders
0.657 0.342 0.000
L88 Pyoderma gangrenosum
0.657 0.342 0.000
L86 Keratoderma in diseases classified elsewhere
0.657 0.342 0.000
L83 Acanthosis nigricans
0.657 0.342 0.000
L80 Vitiligo
0.657 0.342 0.000
I61 Intracerebral haemorrhage
0.657 0.342 0.000
O66 Other obstructed labour
0.656 0.344 0.000
A49.0 Staphylococcal infection, unspecified
0.656 0.344 0.000
L90.5 Scar conditions and fibrosis of skin
0.656 0.344 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.655 0.345 0.000
I74 Arterial embolism and thrombosis
0.655 0.345 0.000
D12.7 Rectosigmoid junction
0.655 0.345 0.000
M54 Dorsalgia
0.654 0.346 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.654 0.346 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.654 0.346 0.000
F10.2 Dependence syndrome
0.653 0.347 0.000
I70 Atherosclerosis
0.653 0.347 0.000
O29 Complications of anaesthesia during pregnancy
0.653 0.347 0.000
O28 Abnormal findings on antenatal screening of mother
0.653 0.347 0.000
O24 Diabetes mellitus in pregnancy
0.653 0.347 0.000
O23 Infections of genito-urinary tract in pregnancy
0.653 0.347 0.000
O22 Venous complications in pregnancy
0.653 0.347 0.000
O25 Malnutrition in pregnancy
0.653 0.347 0.000
I27.0 Primary pulmonary hypertension
0.652 0.348 0.000
R39.2 Extrarenal uraemia
0.652 0.348 0.000
R39.0 Extravasation of urine
0.652 0.348 0.000
C79.2 Secondary malignant neoplasm of skin
0.652 0.348 0.000
T82.1 Mechanical complication of cardiac electronic device
0.652 0.348 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.651 0.349 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.651 0.349 0.000
I13 Hypertensive heart and renal disease
0.650 0.349 0.000
I11 Hypertensive heart disease
0.650 0.349 0.000
J98.4 Other disorders of lung
0.650 0.350 0.000
C09 Malignant neoplasm of tonsil
0.649 0.351 0.000
R74 Abnormal serum enzyme levels
0.648 0.351 0.000
M25 Other joint disorders, not elsewhere classified
0.648 0.352 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.648 0.352 0.000
D32 Benign neoplasm of meninges
0.647 0.353 0.000
M14 Arthropathies in other diseases classified elsewhere
0.646 0.354 0.000
M12 Other specific arthropathies
0.646 0.354 0.000
M11 Other crystal arthropathies
0.646 0.354 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.646 0.354 0.000
M08 Juvenile arthritis
0.646 0.354 0.000
D12.0 Caecum
0.646 0.354 0.000
A48 Other bacterial diseases, not elsewhere classified
0.646 0.354 0.000
A44 Bartonellosis
0.646 0.354 0.000
A43 Nocardiosis
0.646 0.354 0.000
A42 Actinomycosis
0.646 0.354 0.000
A40 Streptococcal septicaemia
0.646 0.354 0.000
A39 Meningococcal infection
0.646 0.354 0.000
A37 Whooping cough
0.646 0.354 0.000
A36 Diphtheria
0.646 0.354 0.000
A32 Listeriosis
0.646 0.354 0.000
A31 Infection due to other mycobacteria
0.646 0.354 0.000
A30 Leprosy [Hansen's disease]
0.646 0.354 0.000
A46 Erysipelas
0.646 0.354 0.000
A38 Scarlet fever
0.646 0.354 0.000
A35 Other tetanus
0.646 0.354 0.000
A34 Obstetrical tetanus
0.646 0.354 0.000
A33 Tetanus neonatorum
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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