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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77822622
log Bayes Factor = 16.7219
Chromosome 8   position 57,929,662  (GRCh37) Explore rs77822622 on Ensembl!
Variant rs77822622 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter II Neoplasms
0.994 0.006 0.000
I20 Angina pectoris
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
K70-K77 Diseases of liver
0.991 0.009 0.000
I10-I15 Hypertensive diseases
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
I20.0 Unstable angina
0.985 0.015 0.000
I10 Essential (primary) hypertension
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.973 0.027 0.000
N17-N19 Renal failure
0.971 0.029 0.000
N10-N16 Renal tubulo-interstitial diseases
0.970 0.030 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.970 0.030 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.967 0.033 0.000
E10-E14 Diabetes mellitus
0.965 0.035 0.000
I21 Acute myocardial infarction
0.963 0.037 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.960 0.040 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.955 0.045 0.000
Chapter VIII Diseases of the ear and mastoid process
0.953 0.047 0.000
K74 Fibrosis and cirrhosis of liver
0.953 0.047 0.000
R50-R69 General symptoms and signs
0.951 0.049 0.000
N13 Obstructive and reflux uropathy
0.949 0.051 0.000
K70 Alcoholic liver disease
0.948 0.052 0.000
G90-G99 Other disorders of the nervous system
0.947 0.053 0.000
R94 Abnormal results of function studies
0.947 0.053 0.000
I22 Subsequent myocardial infarction
0.946 0.054 0.000
R94.5 Abnormal results of liver function studies
0.940 0.060 0.000
I60-I69 Cerebrovascular diseases
0.937 0.063 0.000
H90-H95 Other disorders of ear
0.937 0.063 0.000
I95 Hypotension
0.935 0.065 0.000
C77.2 Intra-abdominal lymph nodes
0.935 0.065 0.000
N19 Unspecified renal failure
0.927 0.073 0.000
K74.6 Other and unspecified cirrhosis of liver
0.926 0.074 0.000
I34 Nonrheumatic mitral valve disorders
0.921 0.079 0.000
R51 Headache
0.918 0.082 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.917 0.083 0.000
Chapter I Certain infectious and parasitic diseases
0.916 0.084 0.000
E10 Insulin-dependent diabetes mellitus
0.916 0.084 0.000
R50 Fever of unknown origin
0.914 0.086 0.000
E20-E35 Disorders of other endocrine glands
0.912 0.088 0.000
I44 Atrioventricular and left bundle-branch block
0.910 0.090 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.908 0.092 0.000
H91 Other hearing loss
0.907 0.093 0.000
K70.3 Alcoholic cirrhosis of liver
0.906 0.094 0.000
Chapter XX External causes of morbidity and mortality
0.904 0.096 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.900 0.100 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.892 0.108 0.000
I25 Chronic ischaemic heart disease
0.890 0.110 0.000
K75 Other inflammatory liver diseases
0.887 0.113 0.000
I35 Nonrheumatic aortic valve disorders
0.886 0.114 0.000
H91.9 Hearing loss, unspecified
0.886 0.114 0.000
I34.0 Mitral (valve) insufficiency
0.886 0.114 0.000
C15-C26 Malignant neoplasms of digestive organs
0.885 0.115 0.000
I69 Sequelae of cerebrovascular disease
0.880 0.120 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.879 0.121 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.870 0.130 0.000
I95.9 Hypotension, unspecified
0.869 0.131 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.867 0.133 0.000
N13.3 Other and unspecified hydronephrosis
0.863 0.137 0.000
C77.0 Lymph nodes of head, face and neck
0.863 0.137 0.000
R63 Symptoms and signs concerning food and fluid intake
0.863 0.137 0.000
E10.9 Without complications
0.862 0.138 0.000
G95 Other diseases of spinal cord
0.862 0.138 0.000
A00-A09 Intestinal infectious diseases
0.856 0.144 0.000
N18 Chronic renal failure
0.855 0.145 0.000
R50.9 Fever, unspecified
0.854 0.146 0.000
K90-K93 Other diseases of the digestive system
0.854 0.146 0.000
E11 Non-insulin-dependent diabetes mellitus
0.851 0.149 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.850 0.150 0.000
Chapter XXI Factors influencing health status and contact with health services
0.848 0.152 0.000
G93 Other disorders of brain
0.848 0.152 0.000
I71 Aortic aneurysm and dissection
0.844 0.156 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.844 0.156 0.000
I73 Other peripheral vascular diseases
0.843 0.157 0.000
C51-C58 Malignant neoplasms of female genital organs
0.841 0.159 0.000
K50-K52 Noninfective enteritis and colitis
0.841 0.159 0.000
K76 Other diseases of liver
0.840 0.160 0.000
I21.9 Acute myocardial infarction, unspecified
0.840 0.160 0.000
Chapter VII Diseases of the eye and adnexa
0.839 0.161 0.000
R60 Oedema, not elsewhere classified
0.839 0.161 0.000
I61 Intracerebral haemorrhage
0.839 0.161 0.000
E65-E68 Obesity and other hyperalimentation
0.838 0.162 0.000
N20-N23 Urolithiasis
0.835 0.165 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.834 0.166 0.000
I44.1 Atrioventricular block, second degree
0.833 0.167 0.000
N00-N08 Glomerular diseases
0.832 0.168 0.000
I25.1 Atherosclerotic heart disease
0.831 0.169 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.831 0.169 0.000
I31 Other diseases of pericardium
0.829 0.171 0.000
I95.1 Orthostatic hypotension
0.827 0.173 0.000
I35.0 Aortic (valve) stenosis
0.823 0.177 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.822 0.178 0.000
C60-C63 Malignant neoplasms of male genital organs
0.822 0.178 0.000
I72 Other aneurysm
0.821 0.179 0.000
I24 Other acute ischaemic heart diseases
0.820 0.180 0.000
G40-G47 Episodic and paroxysmal disorders
0.820 0.180 0.000
A30-A49 Other bacterial diseases
0.820 0.180 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.819 0.181 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.819 0.181 0.000
K72 Hepatic failure, not elsewhere classified
0.818 0.182 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.817 0.183 0.000
I74 Arterial embolism and thrombosis
0.815 0.185 0.000
M20-M25 Other joint disorders
0.811 0.189 0.000
A04 Other bacterial intestinal infections
0.809 0.191 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.806 0.194 0.000
N17 Acute renal failure
0.805 0.195 0.000
C77.5 Intrapelvic lymph nodes
0.804 0.196 0.000
I63 Cerebral infarction
0.804 0.196 0.000
N18.9 Chronic renal failure, unspecified
0.798 0.202 0.000
I05-I09 Chronic rheumatic heart diseases
0.797 0.203 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.794 0.205 0.000
I20.8 Other forms of angina pectoris
0.794 0.206 0.000
N10 Acute tubulo-interstitial nephritis
0.792 0.208 0.000
N20 Calculus of kidney and ureter
0.791 0.209 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.788 0.212 0.000
G95.2 Cord compression, unspecified
0.788 0.212 0.000
R50.0 Fever with chills
0.788 0.212 0.000
K65-K67 Diseases of peritoneum
0.787 0.213 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.786 0.214 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.785 0.215 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.784 0.216 0.000
G30-G32 Other degenerative diseases of the nervous system
0.784 0.216 0.000
C15 Malignant neoplasm of oesophagus
0.781 0.219 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.780 0.219 0.000
K73 Chronic hepatitis, not elsewhere classified
0.780 0.220 0.000
C77.9 Lymph node, unspecified
0.779 0.221 0.000
E11.9 Without complications
0.778 0.222 0.000
I44.7 Left bundle-branch block, unspecified
0.778 0.222 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.773 0.227 0.000
B35-B49 Mycoses
0.773 0.227 0.000
F30-F39 Mood [affective] disorders
0.771 0.229 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.769 0.231 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.769 0.231 0.000
H90 Conductive and sensorineural hearing loss
0.768 0.232 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.768 0.232 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.767 0.232 0.000
I77 Other disorders of arteries and arterioles
0.766 0.234 0.000
N25-N29 Other disorders of kidney and ureter
0.766 0.234 0.000
E27 Other disorders of adrenal gland
0.765 0.234 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.764 0.236 0.000
K35-K38 Diseases of appendix
0.762 0.238 0.000
C90.0 Multiple myeloma
0.761 0.239 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.761 0.239 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.760 0.240 0.000
I25.2 Old myocardial infarction
0.760 0.240 0.000
I50 Heart failure
0.758 0.242 0.000
N20.1 Calculus of ureter
0.758 0.242 0.000
H92 Otalgia and effusion of ear
0.757 0.243 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.757 0.243 0.000
G40 Epilepsy
0.757 0.243 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.754 0.246 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.754 0.246 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.752 0.248 0.000
D69 Purpura and other haemorrhagic conditions
0.751 0.249 0.000
R60.0 Localised oedema
0.751 0.249 0.000
K76.6 Portal hypertension
0.748 0.252 0.000
D68 Other coagulation defects
0.747 0.253 0.000
R79 Other abnormal findings of blood chemistry
0.747 0.253 0.000
K75.9 Inflammatory liver disease, unspecified
0.747 0.253 0.000
C54 Malignant neoplasm of corpus uteri
0.747 0.253 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.745 0.255 0.000
F99-F99 Unspecified mental disorder
0.745 0.255 0.000
I20.9 Angina pectoris, unspecified
0.745 0.255 0.000
N11 Chronic tubulo-interstitial nephritis
0.745 0.255 0.000
G62 Other polyneuropathies
0.745 0.255 0.000
M35 Other systemic involvement of connective tissue
0.744 0.256 0.000
N03 Chronic nephritic syndrome
0.743 0.257 0.000
K70.4 Alcoholic hepatic failure
0.742 0.258 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.742 0.258 0.000
G90 Disorders of autonomic nervous system
0.742 0.258 0.000
A04.5 Campylobacter enteritis
0.740 0.260 0.000
C79 Secondary malignant neoplasm of other sites
0.738 0.262 0.000
I44.2 Atrioventricular block, complete
0.738 0.262 0.000
K51 Ulcerative colitis
0.738 0.262 0.000
R63.4 Abnormal weight loss
0.734 0.266 0.000
E13 Other specified diabetes mellitus
0.733 0.267 0.000
A41 Other septicaemia
0.733 0.267 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.733 0.267 0.000
G93.3 Postviral fatigue syndrome
0.732 0.268 0.000
E50-E64 Other nutritional deficiencies
0.730 0.270 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
E66 Obesity
0.730 0.270 0.000
E40-E46 Malnutrition
0.729 0.271 0.000
F60-F69 Disorders of adult personality and behaviour
0.728 0.272 0.000
I70 Atherosclerosis
0.728 0.272 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.728 0.272 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.727 0.273 0.000
K75.8 Other specified inflammatory liver diseases
0.726 0.274 0.000
R53 Malaise and fatigue
0.726 0.274 0.000
R63.1 Polydipsia
0.726 0.274 0.000
R63.5 Abnormal weight gain
0.725 0.275 0.000
K92 Other diseases of digestive system
0.724 0.276 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.723 0.277 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.722 0.278 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.722 0.278 0.000
G40.9 Epilepsy, unspecified
0.721 0.279 0.000
C80 Malignant neoplasm without specification of site
0.720 0.280 0.000
R94.3 Abnormal results of cardiovascular function studies
0.719 0.281 0.000
M23 Internal derangement of knee
0.719 0.281 0.000
E24 Cushing's syndrome
0.719 0.281 0.000
C16 Malignant neoplasm of stomach
0.718 0.282 0.000
I78 Diseases of capillaries
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.716 0.284 0.000
E14 Unspecified diabetes mellitus
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
D45 Polycythaemia vera
0.713 0.287 0.000
F10.0 Acute intoxication
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
I20.1 Angina pectoris with documented spasm
0.712 0.288 0.000
K77 Liver disorders in diseases classified elsewhere
0.711 0.289 0.000
K71 Toxic liver disease
0.711 0.289 0.000
I15 Secondary hypertension
0.710 0.290 0.000
I13 Hypertensive heart and renal disease
0.710 0.290 0.000
I11 Hypertensive heart disease
0.710 0.290 0.000
I24.8 Other forms of acute ischaemic heart disease
0.710 0.290 0.000
E10.3 With ophthalmic complications
0.709 0.291 0.000
I12 Hypertensive renal disease
0.709 0.291 0.000
R74 Abnormal serum enzyme levels
0.708 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.708 0.292 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.708 0.292 0.000
E29 Testicular dysfunction
0.707 0.293 0.000
H30-H36 Disorders of choroid and retina
0.706 0.294 0.000
M80-M85 Disorders of bone density and structure
0.706 0.294 0.000
K90 Intestinal malabsorption
0.706 0.294 0.000
I49 Other cardiac arrhythmias
0.705 0.294 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.704 0.296 0.000
I73.0 Raynaud's syndrome
0.703 0.297 0.000
I95.2 Hypotension due to drugs
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.702 0.298 0.000
W20-W49 Exposure to inanimate mechanical forces
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I30 Acute pericarditis
0.702 0.298 0.000
C09 Malignant neoplasm of tonsil
0.699 0.301 0.000
E10.4 With neurological complications
0.699 0.301 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.698 0.302 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.698 0.302 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.697 0.302 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.696 0.304 0.000
N15 Other renal tubulo-interstitial diseases
0.696 0.304 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.696 0.304 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.695 0.304 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.694 0.305 0.000
I99 Other and unspecified disorders of circulatory system
0.694 0.305 0.000
H93 Other disorders of ear, not elsewhere classified
0.694 0.306 0.000
K70.9 Alcoholic liver disease, unspecified
0.694 0.306 0.000
K72.9 Hepatic failure, unspecified
0.694 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.693 0.306 0.000
F70-F79 Mental retardation
0.693 0.306 0.000
C50-C50 Malignant neoplasm of breast
0.692 0.308 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.692 0.308 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.692 0.308 0.000
E12 Malnutrition-related diabetes mellitus
0.692 0.308 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.692 0.308 0.000
M22 Disorders of patella
0.692 0.308 0.000
R61 Hyperhidrosis
0.691 0.309 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.691 0.309 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.691 0.309 0.000
C21 Malignant neoplasm of anus and anal canal
0.690 0.310 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.690 0.310 0.000
M21 Other acquired deformities of limbs
0.689 0.311 0.000
C77.8 Lymph nodes of multiple regions
0.688 0.312 0.000
C77.4 Inguinal and lower limb lymph nodes
0.688 0.312 0.000
F10.3 Withdrawal state
0.687 0.313 0.000
K92.0 Haematemesis
0.686 0.314 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.686 0.314 0.000
N99-N99 Other disorders of the genitourinary system
0.686 0.314 0.000
N17.9 Acute renal failure, unspecified
0.686 0.314 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.685 0.315 0.000
Z45 Adjustment and management of implanted device
0.683 0.316 0.000
K74.5 Biliary cirrhosis, unspecified
0.683 0.317 0.000
K74.4 Secondary biliary cirrhosis
0.683 0.317 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.683 0.317 0.000
K74.1 Hepatic sclerosis
0.683 0.317 0.000
K74.0 Hepatic fibrosis
0.683 0.317 0.000
I33 Acute and subacute endocarditis
0.683 0.317 0.000
R50.8 Other specified fever
0.682 0.318 0.000
R68 Other general symptoms and signs
0.682 0.318 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.682 0.318 0.000
R62 Lack of expected normal physiological development
0.682 0.318 0.000
R57 Shock, not elsewhere classified
0.682 0.318 0.000
R64 Cachexia
0.682 0.318 0.000
R58 Haemorrhage, not elsewhere classified
0.682 0.318 0.000
C92 Myeloid leukaemia
0.681 0.319 0.000
N13.8 Other obstructive and reflux uropathy
0.680 0.320 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.680 0.320 0.000
N13.6 Pyonephrosis
0.680 0.320 0.000
N13.4 Hydroureter
0.680 0.320 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.680 0.320 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.680 0.320 0.000
K70.1 Alcoholic hepatitis
0.680 0.320 0.000
K70.0 Alcoholic fatty liver
0.680 0.320 0.000
N03.9 Unspecified
0.680 0.320 0.000
C54.1 Endometrium
0.679 0.321 0.000
W00-W19 Falls
0.679 0.321 0.000
G96 Other disorders of central nervous system
0.679 0.321 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.679 0.321 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.679 0.321 0.000
G92 Toxic encephalopathy
0.679 0.321 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.679 0.321 0.000
R94.7 Abnormal results of other endocrine function studies
0.679 0.321 0.000
R94.6 Abnormal results of thyroid function studies
0.679 0.321 0.000
R94.4 Abnormal results of kidney function studies
0.679 0.321 0.000
R94.2 Abnormal results of pulmonary function studies
0.679 0.321 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.679 0.321 0.000
R94.0 Abnormal results of function studies of central nervous system
0.679 0.321 0.000
I22.8 Subsequent myocardial infarction of other sites
0.678 0.322 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.678 0.322 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.678 0.322 0.000
I73.9 Peripheral vascular disease, unspecified
0.677 0.323 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.677 0.323 0.000
Chapter XXII Codes for special purposes
0.677 0.323 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.677 0.323 0.000
K75.4 Autoimmune hepatitis
0.677 0.323 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.676 0.324 0.000
F10.1 Harmful use
0.675 0.325 0.000
I50.1 Left ventricular failure
0.675 0.325 0.000
I31.3 Pericardial effusion (noninflammatory)
0.674 0.326 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.674 0.326 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.673 0.327 0.000
K74.3 Primary biliary cirrhosis
0.673 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.672 0.328 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.672 0.328 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.672 0.328 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.672 0.328 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.671 0.329 0.000
I72.3 Aneurysm of iliac artery
0.671 0.329 0.000
I95.8 Other hypotension
0.671 0.329 0.000
I95.0 Idiopathic hypotension
0.671 0.329 0.000
B37 Candidiasis
0.670 0.330 0.000
C61 Malignant neoplasm of prostate
0.670 0.330 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000
H60-H62 Diseases of external ear
0.667 0.333 0.000
I25.5 Ischaemic cardiomyopathy
0.667 0.333 0.000
I31.9 Disease of pericardium, unspecified
0.666 0.333 0.000
C81 Hodgkin's disease
0.666 0.334 0.000
G93.0 Cerebral cysts
0.665 0.335 0.000
G62.9 Polyneuropathy, unspecified
0.665 0.335 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.664 0.336 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.664 0.336 0.000
A41.9 Septicaemia, unspecified
0.664 0.336 0.000
I21.4 Acute subendocardial myocardial infarction
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
D60-D64 Aplastic and other anaemias
0.662 0.338 0.000
I45 Other conduction disorders
0.662 0.338 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.662 0.338 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.660 0.340 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.660 0.340 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.660 0.340 0.000
G95.9 Disease of spinal cord, unspecified
0.660 0.340 0.000
D80-D89 Certain disorders involving the immune mechanism
0.659 0.341 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.658 0.342 0.000
R54 Senility
0.658 0.342 0.000
F10.2 Dependence syndrome
0.657 0.342 0.000
B99-B99 Other infectious diseases
0.657 0.343 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.657 0.343 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.657 0.343 0.000
B65-B83 Helminthiases
0.657 0.343 0.000
B50-B64 Protozoal diseases
0.657 0.343 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.657 0.343 0.000
B15-B19 Viral hepatitis
0.657 0.343 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.657 0.343 0.000
A80-A89 Viral infections of the central nervous system
0.657 0.343 0.000
A75-A79 Rickettsioses
0.657 0.343 0.000
A70-A74 Other diseases caused by chlamydiae
0.657 0.343 0.000
A65-A69 Other spirochaetal diseases
0.657 0.343 0.000
A20-A28 Certain zoonotic bacterial diseases
0.657 0.343 0.000
A15-A19 Tuberculosis
0.657 0.343 0.000
I47 Paroxysmal tachycardia
0.657 0.343 0.000
M35.3 Polymyalgia rheumatica
0.657 0.343 0.000
E10.8 With unspecified complications
0.656 0.343 0.000
E10.7 With multiple complications
0.656 0.343 0.000
E10.6 With other specified complications
0.656 0.343 0.000
E10.5 With peripheral circulatory complications
0.656 0.343 0.000
E10.2 With renal complications
0.656 0.343 0.000
E10.1 With ketoacidosis
0.656 0.343 0.000
E10.0 With coma
0.656 0.343 0.000
C15.9 Oesophagus, unspecified
0.657 0.343 0.000
C51 Malignant neoplasm of vulva
0.656 0.344 0.000
R50.2 Drug-induced fever
0.655 0.345 0.000
R50.1 Persistent fever
0.655 0.345 0.000
C77.1 Intrathoracic lymph nodes
0.655 0.345 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.655 0.345 0.000
G93.8 Other specified disorders of brain
0.654 0.346 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.654 0.346 0.000
E34 Other endocrine disorders
0.654 0.346 0.000
E32 Diseases of thymus
0.654 0.346 0.000
E31 Polyglandular dysfunction
0.654 0.346 0.000
E30 Disorders of puberty, not elsewhere classified
0.654 0.346 0.000
E26 Hyperaldosteronism
0.654 0.346 0.000
E25 Adrenogenital disorders
0.654 0.346 0.000
E22 Hyperfunction of pituitary gland
0.654 0.346 0.000
E20 Hypoparathyroidism
0.654 0.346 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.654 0.346 0.000
F43 Reaction to severe stress, and adjustment disorders
0.653 0.346 0.000
N18.2 Chronic kidney disease, stage 2
0.653 0.347 0.000
I44.6 Other and unspecified fascicular block
0.652 0.348 0.000
I44.5 Left posterior fascicular block
0.652 0.348 0.000
I44.4 Left anterior fascicular block
0.652 0.348 0.000
I44.3 Other and unspecified atrioventricular block
0.652 0.348 0.000
E28 Ovarian dysfunction
0.651 0.349 0.000
D55-D59 Haemolytic anaemias
0.651 0.349 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.651 0.349 0.000
K52 Other non-infective gastro-enteritis and colitis
0.651 0.349 0.000
H91.8 Other specified hearing loss
0.650 0.349 0.000
H91.3 Deaf mutism, not elsewhere classified
0.650 0.349 0.000
H91.2 Sudden idiopathic hearing loss
0.650 0.349 0.000
H91.1 Presbycusis
0.650 0.349 0.000
H91.0 Ototoxic hearing loss
0.650 0.349 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.650 0.350 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.650 0.350 0.000
C15.5 Lower third of oesophagus
0.649 0.351 0.000
R23 Other skin changes
0.649 0.351 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.648 0.352 0.000
Y35-Y36 Legal intervention and operations of war
0.648 0.352 0.000
Y10-Y34 Event of undetermined intent
0.648 0.352 0.000
Y00-Y09 Assault
0.648 0.352 0.000
X85-X99 Assault
0.648 0.352 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.648 0.352 0.000
X50-X57 Overexertion, travel and privation
0.648 0.352 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.648 0.352 0.000
X30-X39 Exposure to forces of nature
0.648 0.352 0.000
X20-X29 Contact with venomous animals and plants
0.648 0.352 0.000
X10-X19 Contact with heat and hot substances
0.648 0.352 0.000
X00-X09 Exposure to smoke, fire and flames
0.648 0.352 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.648 0.352 0.000
W75-W84 Other accidental threats to breathing
0.648 0.352 0.000
W65-W74 Accidental drowning and submersion
0.648 0.352 0.000
W50-W64 Exposure to animate mechanical forces
0.648 0.352 0.000
V98-V99 Other and unspecified transport accidents
0.648 0.352 0.000
V95-V97 Air and space transport accidents
0.648 0.352 0.000
V90-V94 Water transport accidents
0.648 0.352 0.000
V80-V89 Other land transport accidents
0.648 0.352 0.000
V70-V79 Bus occupant injured in transport accident
0.648 0.352 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.648 0.352 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.648 0.352 0.000
V40-V49 Car occupant injured in transport accident
0.648 0.352 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.648 0.352 0.000
V20-V29 Motorcycle rider injured in transport accident
0.648 0.352 0.000
V01-V09 Pedestrian injured in transport accident
0.648 0.352 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.648 0.352 0.000
Z48 Other surgical follow-up care
0.647 0.353 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.647 0.353 0.000
K76.9 Liver disease, unspecified
0.646 0.354 0.000
G20-G26 Extrapyramidal and movement disorders
0.646 0.354 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.645 0.355 0.000
C95 Leukaemia of unspecified cell type
0.645 0.355 0.000
C94 Other leukaemias of specified cell type
0.645 0.355 0.000
C93 Monocytic leukaemia
0.645 0.355 0.000
C88 Malignant immunoproliferative diseases
0.645 0.355 0.000
C86 Other specified types of T/NK-cell lymphoma
0.645 0.355 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.645 0.355 0.000
A08 Viral and other specified intestinal infections
0.645 0.355 0.000
I35.1 Aortic (valve) insufficiency
0.645 0.355 0.000
I72.4 Aneurysm of artery of lower extremity
0.645 0.355 0.000
Y83.3 Surgical operation with formation of external stoma
0.645 0.355 0.000
E66.8 Other obesity
0.645 0.355 0.000
R76 Other abnormal immunological findings in serum
0.643 0.357 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.643 0.357 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.643 0.357 0.000
I62 Other nontraumatic intracranial haemorrhage
0.642 0.357 0.000
D69.6 Thrombocytopenia, unspecified
0.641 0.359 0.000
E11.3 With ophthalmic complications
0.640 0.360 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.639 0.360 0.000
N18.5 Chronic kidney disease, stage 5
0.639 0.361 0.000
G12 Spinal muscular atrophy and related syndromes
0.638 0.361 0.000
I25.6 Silent myocardial ischaemia
0.638 0.362 0.000
I25.4 Coronary artery aneurysm
0.638 0.362 0.000
I25.3 Aneurysm of heart
0.638 0.362 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.638 0.362 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.637 0.363 0.000
A49 Bacterial infection of unspecified site
0.636 0.364 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.636 0.364 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.636 0.364 0.000
K75.2 Nonspecific reactive hepatitis
0.636 0.364 0.000
K75.1 Phlebitis of portal vein
0.636 0.364 0.000
K75.0 Abscess of liver
0.636 0.364 0.000
I35.9 Aortic valve disorder, unspecified
0.635 0.364 0.000
I35.8 Other aortic valve disorders
0.635 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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