TreeWAS – Variant ID: rs13281609

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35 Nonrheumatic aortic valve disorders	0.081	0.919	0.000
I35.0 Aortic (valve) stenosis	0.078	0.922	0.000
I34 Nonrheumatic mitral valve disorders	0.077	0.923	0.000
I31 Other diseases of pericardium	0.075	0.925	0.000
I31.3 Pericardial effusion (noninflammatory)	0.075	0.925	0.000
I34.1 Mitral (valve) prolapse	0.074	0.926	0.000
I30-I52 Other forms of heart disease	0.074	0.926	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.074	0.926	0.000
I35.1 Aortic (valve) insufficiency	0.072	0.928	0.000
I49 Other cardiac arrhythmias	0.072	0.928	0.000
I34.0 Mitral (valve) insufficiency	0.071	0.929	0.000
I49.3 Ventricular premature depolarisation	0.070	0.930	0.000
I47 Paroxysmal tachycardia	0.067	0.933	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.065	0.935	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.064	0.936	0.000
I49.5 Sick sinus syndrome	0.063	0.937	0.000
I51 Complications and ill-defined descriptions of heart disease	0.062	0.938	0.000
I51.8 Other ill-defined heart diseases	0.062	0.938	0.000
I31.9 Disease of pericardium, unspecified	0.062	0.938	0.000
I49.4 Other and unspecified premature depolarisation	0.061	0.939	0.000
I35.9 Aortic valve disorder, unspecified	0.061	0.939	0.000
I35.8 Other aortic valve disorders	0.058	0.941	0.000
I33 Acute and subacute endocarditis	0.058	0.942	0.000
I31.0 Chronic adhesive pericarditis	0.058	0.942	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.056	0.944	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.056	0.944	0.000
I31.8 Other specified diseases of pericardium	0.054	0.946	0.000
I31.2 Haemopericardium, not elsewhere classified	0.054	0.946	0.000
I31.1 Chronic constrictive pericarditis	0.054	0.946	0.000
I52 Other heart disorders in diseases classified elsewhere	0.054	0.946	0.000
I48 Atrial fibrillation and flutter	0.054	0.946	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.054	0.946	0.000
I41 Myocarditis in diseases classified elsewhere	0.054	0.946	0.000
I40 Acute myocarditis	0.054	0.946	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.054	0.946	0.000
I32 Pericarditis in diseases classified elsewhere	0.054	0.946	0.000
I49.2 Junctional premature depolarisation	0.052	0.948	0.000
I49.1 Atrial premature depolarisation	0.051	0.949	0.000
I51.4 Myocarditis, unspecified	0.050	0.950	0.000
I47.1 Supraventricular tachycardia	0.049	0.951	0.000
I38 Endocarditis, valve unspecified	0.049	0.951	0.000
I37 Pulmonary valve disorders	0.048	0.952	0.000
I51.6 Cardiovascular disease, unspecified	0.048	0.952	0.000
I47.0 Reentry ventricular arrhythmia	0.047	0.953	0.000
I49.0 Ventricular fibrillation and flutter	0.047	0.953	0.000
I30 Acute pericarditis	0.046	0.954	0.000
I33.0 Acute and subacute infective endocarditis	0.046	0.954	0.000
I51.5 Myocardial degeneration	0.045	0.955	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.045	0.955	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.044	0.956	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.044	0.956	0.000
I49.9 Cardiac arrhythmia, unspecified	0.043	0.957	0.000
I33.9 Acute endocarditis, unspecified	0.041	0.958	0.000
I36 Nonrheumatic tricuspid valve disorders	0.041	0.959	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.038	0.961	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.038	0.961	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.038	0.961	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.038	0.961	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.038	0.961	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.038	0.961	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.038	0.961	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.038	0.961	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.038	0.961	0.000
I40.9 Acute myocarditis, unspecified	0.038	0.961	0.000
I40.8 Other acute myocarditis	0.038	0.961	0.000
I40.1 Isolated myocarditis	0.038	0.961	0.000
I40.0 Infective myocarditis	0.038	0.961	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.038	0.961	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.038	0.961	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.038	0.961	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.038	0.961	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.038	0.961	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.038	0.961	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.038	0.961	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.038	0.961	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.038	0.961	0.000
I48.4 Atypical atrial flutter	0.038	0.961	0.000
I48.3 Typical atrial flutter	0.038	0.961	0.000
I48.2 Chronic atrial fibrillation	0.038	0.961	0.000
I48.1 Persistent atrial fibrillation	0.038	0.961	0.000
I48.0 Paroxysmal atrial fibrillation	0.038	0.961	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.038	0.961	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.038	0.961	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.038	0.961	0.000
I49.8 Other specified cardiac arrhythmias	0.038	0.962	0.000
I51.0 Cardiac septal defect, acquired	0.035	0.964	0.000
I37.9 Pulmonary valve disorder, unspecified	0.035	0.965	0.000
I37.8 Other pulmonary valve disorders	0.035	0.965	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.035	0.965	0.000
I37.0 Pulmonary valve stenosis	0.035	0.965	0.000
I51.9 Heart disease, unspecified	0.035	0.965	0.000
I30.8 Other forms of acute pericarditis	0.033	0.967	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.033	0.967	0.000
I30.9 Acute pericarditis, unspecified	0.030	0.970	0.000
I37.1 Pulmonary valve insufficiency	0.030	0.970	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.029	0.970	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.029	0.970	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.029	0.970	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.029	0.970	0.000
S02.20 Fracture of nasal bones (closed)	0.029	0.971	0.000
I30.1 Infective pericarditis	0.029	0.971	0.000
I47.2 Ventricular tachycardia	0.027	0.973	0.000
I46 Cardiac arrest	0.025	0.974	0.000
Z95.4 Presence of other heart-valve replacement	0.022	0.978	0.000
I50 Heart failure	0.019	0.981	0.000
I46.1 Sudden cardiac death, so described	0.018	0.981	0.000
I42 Cardiomyopathy	0.017	0.983	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.016	0.983	0.001
I42.8 Other cardiomyopathies	0.014	0.986	0.000
S02.2 Fracture of nasal bones	0.014	0.986	0.000
I50.9 Heart failure, unspecified	0.014	0.986	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.013	0.987	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.987	0.000
I42.5 Other restrictive cardiomyopathy	0.012	0.987	0.000
I42.4 Endocardial fibroelastosis	0.012	0.987	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.012	0.987	0.000
I46.9 Cardiac arrest, unspecified	0.012	0.988	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.010	0.990	0.000
S02.21 Fracture of nasal bones (open)	0.010	0.990	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.010	0.990	0.000
I42.6 Alcoholic cardiomyopathy	0.010	0.990	0.000
I51.7 Cardiomegaly	0.010	0.990	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.010	0.990	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.009	0.991	0.000
I44 Atrioventricular and left bundle-branch block	0.009	0.991	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.008	0.992	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.008	0.992	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.008	0.992	0.000
T88.9 Complication of surgical and medical care, unspecified	0.008	0.992	0.000
I42.9 Cardiomyopathy, unspecified	0.007	0.992	0.000
T88.5 Other complications of anaesthesia	0.007	0.993	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.007	0.993	0.000
I42.2 Other hypertrophic cardiomyopathy	0.006	0.993	0.001
I46.0 Cardiac arrest with successful resuscitation	0.006	0.993	0.000
T88.4 Failed or difficult intubation	0.007	0.993	0.000
I42.0 Dilated cardiomyopathy	0.007	0.993	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.007	0.993	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.006	0.993	0.000
I44.5 Left posterior fascicular block	0.006	0.994	0.000
I44.4 Left anterior fascicular block	0.006	0.994	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.006	0.994	0.000
I50.1 Left ventricular failure	0.006	0.994	0.000
T82.3 Mechanical complication of other vascular grafts	0.006	0.994	0.000
Z95.2 Presence of prosthetic heart valve	0.006	0.994	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.006	0.994	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.006	0.994	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.006	0.994	0.000
T88.2 Shock due to anaesthesia	0.006	0.994	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.006	0.994	0.000
T88.0 Infection following immunisation	0.006	0.994	0.000
J81 Pulmonary oedema	0.000	0.994	0.006
I44.3 Other and unspecified atrioventricular block	0.005	0.994	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.005	0.994	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.005	0.995	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.005	0.995	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.995	0.005
I44.6 Other and unspecified fascicular block	0.005	0.995	0.000
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
I44.0 Atrioventricular block, first degree	0.005	0.995	0.000
I44.1 Atrioventricular block, second degree	0.005	0.995	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.005	0.995	0.000
I85.9 Oesophageal varices without bleeding	0.005	0.995	0.000
I45 Other conduction disorders	0.004	0.995	0.001
Z95 Presence of cardiac and vascular implants and grafts	0.005	0.995	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
D23.6 Skin of upper limb, including shoulder	0.005	0.995	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.995	0.004
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.004	0.995	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T80.6 Other serum reactions	0.004	0.996	0.000
T80.5 Anaphylactic shock due to serum	0.004	0.996	0.000
T80.4 Rh incompatibility reaction	0.004	0.996	0.000
T80.3 ABO incompatibility reaction	0.004	0.996	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.004	0.996	0.000
C44.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
T86.0 Bone-marrow transplant rejection	0.004	0.996	0.000
T86 Failure and rejection of transplanted organs and tissues	0.004	0.996	0.000
L40.9 Psoriasis, unspecified	0.000	0.996	0.004
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.004	0.996	0.000
L40.5 Arthropathic psoriasis	0.000	0.996	0.004
I70.2 Atherosclerosis of arteries of the extremities	0.004	0.996	0.000
I45.0 Right fascicular block	0.003	0.996	0.001
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.996	0.004
I45.8 Other specified conduction disorders	0.003	0.996	0.000
Z95.3 Presence of xenogenic heart valve	0.004	0.996	0.000
I45.4 Nonspecific intraventricular block	0.003	0.996	0.000
I74.5 Embolism and thrombosis of iliac artery	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
I70 Atherosclerosis	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
I74 Arterial embolism and thrombosis	0.003	0.997	0.000
L40 Psoriasis	0.000	0.997	0.003
I98.2 Oesophageal varices in diseases classified elsewhere	0.003	0.997	0.000
I70.0 Atherosclerosis of aorta	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.003	0.997	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
I45.2 Bifascicular block	0.003	0.997	0.001
K31.8 Other specified diseases of stomach and duodenum	0.003	0.997	0.000
I45.3 Trifascicular block	0.003	0.997	0.001
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.000	0.997	0.003
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.003	0.997	0.000
T86.3 Heart-lung transplant failure and rejection	0.003	0.997	0.000
T86.2 Heart transplant failure and rejection	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.003	0.997	0.000
L40.0 Psoriasis vulgaris	0.000	0.997	0.003
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
I45.5 Other specified heart block	0.002	0.997	0.001
I74.8 Embolism and thrombosis of other arteries	0.003	0.997	0.000
I22 Subsequent myocardial infarction	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
T87 Complications peculiar to reattachment and amputation	0.003	0.997	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.997	0.003
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
Z95.0 Presence of cardiac pacemaker	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
B34.9 Viral infection, unspecified	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.001	0.997	0.002
I70.9 Generalised and unspecified atherosclerosis	0.003	0.997	0.000
I70.8 Atherosclerosis of other arteries	0.003	0.997	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.997	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.003	0.997	0.000
L40.8 Other psoriasis	0.000	0.997	0.003
L40.4 Guttate psoriasis	0.000	0.997	0.003
L40.3 Pustulosis palmaris et plantaris	0.000	0.997	0.003
L40.2 Acrodermatitis continua	0.000	0.997	0.003
L40.1 Generalised pustular psoriasis	0.000	0.997	0.003
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.003	0.997	0.000
Q07.0 Arnold-Chiari syndrome	0.003	0.997	0.000
I08 Multiple valve diseases	0.003	0.997	0.000
J80 Adult respiratory distress syndrome	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.002	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.997	0.000
Q44.4 Choledochal cyst	0.002	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.997	0.000
Q44.2 Atresia of bile ducts	0.002	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.997	0.000
Q04 Other congenital malformations of brain	0.002	0.997	0.000
Q01 Encephalocele	0.002	0.997	0.000
Q00 Anencephaly and similar malformations	0.002	0.997	0.000
Q02 Microcephaly	0.002	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.997	0.000
Q14.1 Congenital malformation of retina	0.002	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.997	0.000
C15.9 Oesophagus, unspecified	0.000	0.997	0.003
Chapter IX Diseases of the circulatory system	0.003	0.997	0.000
Q35 Cleft palate	0.002	0.997	0.000
Q45 Other congenital malformations of digestive system	0.002	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.997	0.000
I85 Oesophageal varices	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
Q39.4 Oesophageal web	0.002	0.998	0.000
I45.9 Conduction disorder, unspecified	0.001	0.998	0.001
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.001
S02.0 Fracture of vault of skull	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q35.9 Cleft palate, unspecified	0.002	0.998	0.000
Q12 Congenital lens malformations	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I98.0 Cardiovascular syphilis	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
T87.5 Necrosis of amputation stump	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.002	0.998	0.000
T87.1 Complications of reattached (part of) lower extremity	0.002	0.998	0.000
T87.0 Complications of reattached (part of) upper extremity	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.000	0.998	0.002
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
H50 Other strabismus	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.002	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.002	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
T87.4 Infection of amputation stump	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
I21.4 Acute subendocardial myocardial infarction	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.001	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.998	0.002
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.002	0.998	0.000
Q35.7 Cleft uvula	0.002	0.998	0.000
Q35.6 Cleft palate, medial	0.002	0.998	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.002	0.998	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.3 Cleft soft palate	0.002	0.998	0.000
Q35.2 (Cleft soft palate, bilateral)	0.002	0.998	0.000
Q35.1 Cleft hard palate	0.002	0.998	0.000
Q35.0 (Cleft hard palate, bilateral)	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations