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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Diagnostic term associations

Hospitalization Episode Statistics (HES)

I06.1
Rheumatic aortic insufficiency
Parent term
I06 Rheumatic aortic valve diseases
What are diagnostic terms?
Variant effects

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
rs75397367 lBF = 8.07931   Chr16 : 84,041,217
0.510 0.490 0.000
rs11864146 lBF = 7.6214   Chr16 : 84,046,715
0.508 0.492 0.000
rs75957893 lBF = 8.17006   Chr16 : 75,381,816
0.505 0.495 0.000
rs80213544 lBF = 10.5045   Chr16 : 75,116,252
0.501 0.499 0.000
rs73598796 lBF = 12.129   Chr16 : 82,025,794
0.499 0.501 0.000
rs8044050 lBF = 16.7322   Chr16 : 74,922,857
0.494 0.506 0.000
rs76475900 lBF = 15.2634   Chr16 : 59,672,738
0.490 0.509 0.000
rs117453948 lBF = 17.5477   Chr16 : 77,965,459
0.482 0.518 0.000
rs72781450 lBF = 8.96513   Chr16 : 13,988,334
0.481 0.519 0.000
rs77859761 lBF = 18.8632   Chr16 : 81,993,215
0.474 0.525 0.000
rs117582629 lBF = 8.51744   Chr16 : 12,456,402
0.472 0.528 0.000
rs117097463 lBF = 17.5524   Chr16 : 48,610,292
0.469 0.530 0.000
rs117268490 lBF = 14.8328   Chr16 : 81,830,515
0.469 0.531 0.000
rs8062326 lBF = 10.0922   Chr16 : 19,156,016
0.465 0.535 0.000
rs113797007 lBF = 25.0423   Chr16 : 12,649,840
0.457 0.542 0.000
rs61744392 lBF = 12.8838   Chr16 : 67,037,035
0.456 0.544 0.000
rs282232 lBF = 13.7114   Chr16 : 56,597,350
0.455 0.545 0.000
rs113920704 lBF = 31.1936   Chr16 : 7,472,397
0.453 0.547 0.000
rs80167425 lBF = 13.1983   Chr16 : 55,715,542
0.451 0.549 0.000
rs666636 lBF = 12.3872   Chr16 : 56,601,720
0.444 0.556 0.000
rs17232120 lBF = 9.61677   Chr16 : 89,880,844
0.441 0.559 0.000
rs4783278 lBF = 8.34675   Chr16 : 82,829,767
0.440 0.560 0.000
rs75781922 lBF = 11.3472   Chr16 : 88,149,539
0.440 0.560 0.000
rs6420398 lBF = 18.8598   Chr16 : 76,991,593
0.439 0.561 0.000
rs76114334 lBF = 19.0254   Chr16 : 83,093,295
0.437 0.562 0.000
rs118183808 lBF = 15.0414   Chr16 : 71,438,393
0.434 0.566 0.000
rs74013184 lBF = 7.38165   Chr16 : 24,363,769
0.429 0.570 0.000
rs78873708 lBF = 28.1642   Chr16 : 7,408,842
0.428 0.572 0.000
rs16970670 lBF = 6.69072   Chr16 : 72,225,187
0.427 0.573 0.000
rs112247854 lBF = 14.4224   Chr16 : 7,291,344
0.426 0.573 0.000
rs77172747 lBF = 11.7522   Chr16 : 67,605,125
0.420 0.579 0.000
rs75896014 lBF = 10.709   Chr16 : 24,531,387
0.419 0.581 0.000
rs11150606 lBF = 14.614   Chr16 : 31,099,011
0.418 0.582 0.000
rs117019691 lBF = 21.5576   Chr16 : 57,505,625
0.418 0.582 0.000
rs11867071 lBF = 14.7556   Chr16 : 68,760,442
0.412 0.587 0.000
rs111696352 lBF = 17.5381   Chr16 : 81,790,491
0.412 0.588 0.000
rs72799290 lBF = 21.6918   Chr16 : 84,121,289
0.411 0.588 0.000
rs76246633 lBF = 27.2748   Chr16 : 74,924,716
0.408 0.592 0.000
rs79656987 lBF = 12.8741   Chr16 : 67,357,900
0.403 0.597 0.000
rs76681713 lBF = 24.4335   Chr16 : 72,333,346
0.402 0.598 0.000
rs117312671 lBF = 24.8436   Chr16 : 67,936,863
0.399 0.601 0.000
rs117664943 lBF = 16.2944   Chr16 : 52,408,480
0.398 0.602 0.000
rs34641959 lBF = 19.1716   Chr16 : 85,568,804
0.396 0.603 0.000
rs112572951 lBF = 28.6867   Chr16 : 7,462,090
0.396 0.603 0.000
rs75193761 lBF = 11.2566   Chr16 : 67,233,243
0.396 0.604 0.000
rs9935937 lBF = 0.946034   Chr16 : 74,986,485
0.395 0.605 0.000
rs112817022 lBF = 21.0666   Chr16 : 22,274,136
0.394 0.606 0.000
rs201918052 lBF = 21.0846   Chr16 : 30,772,988
0.391 0.609 0.000
rs61733768 lBF = 11.6573   Chr16 : 67,213,950
0.391 0.609 0.000
rs79274317 lBF = 9.38319   Chr16 : 7,354,883
0.389 0.611 0.000
rs116183707 lBF = 14.8739   Chr16 : 7,142,287
0.382 0.618 0.000
rs710079 lBF = 14.6065   Chr16 : 129,223
0.380 0.620 0.000
rs113501257 lBF = 17.3074   Chr16 : 21,722,406
0.379 0.621 0.000
rs75885813 lBF = 12.9219   Chr16 : 7,141,263
0.378 0.622 0.000
rs12925413 lBF = 8.50475   Chr16 : 7,241,628
0.371 0.629 0.000
rs12149070 lBF = 10.9184   Chr16 : 70,913,984
0.368 0.632 0.000
rs17674099 lBF = 12.945   Chr16 : 81,506,593
0.367 0.633 0.000
rs138450362 lBF = 1.99354   Chr16 : 22,950,613
0.367 0.633 0.000
rs12691052 lBF = 4.46234   Chr16 : 57,007,512
0.365 0.635 0.000
rs138436123 lBF = 5.39195   Chr16 : 2,978,068
0.363 0.637 0.000
rs9924009 lBF = 6.18168   Chr16 : 11,782,049
0.360 0.639 0.000
rs72791114 lBF = 8.04324   Chr16 : 72,205,671
0.360 0.640 0.000
rs74347133 lBF = 17.4128   Chr16 : 13,216,365
0.358 0.642 0.000
rs56276220 lBF = 14.6281   Chr16 : 28,330,317
0.357 0.643 0.000
rs58563355 lBF = 20.9719   Chr16 : 1,199,938
0.354 0.646 0.000
rs193031333 lBF = 7.91451   Chr16 : 79,189,810
0.353 0.647 0.000
rs12443701 lBF = 16.477   Chr16 : 77,302,444
0.353 0.647 0.000
rs149740259 lBF = 3.65077   Chr16 : 83,783,828
0.353 0.647 0.000
rs55723035 lBF = 12.5757   Chr16 : 75,490,145
0.347 0.653 0.000
rs3751845 lBF = 2.9765   Chr16 : 3,778,337
0.345 0.654 0.000
rs76861960 lBF = 13.3651   Chr16 : 77,599,439
0.344 0.655 0.000
rs9652781 lBF = 17.8088   Chr16 : 195,391
0.344 0.655 0.000
rs117535546 lBF = 19.5942   Chr16 : 65,916,225
0.344 0.656 0.000
rs79272333 lBF = 13.5184   Chr16 : 65,995,651
0.343 0.657 0.000
rs61502801 lBF = 11.9032   Chr16 : 12,248,879
0.342 0.657 0.000
rs181167431 lBF = 11.0835   Chr16 : 74,079,026
0.341 0.659 0.000
rs117254288 lBF = 12.3689   Chr16 : 32,379,046
0.000 0.659 0.340
rs77061563 lBF = 6.51949   Chr16 : 11,452,542
0.338 0.662 0.000
rs1641895 lBF = 14.1003   Chr16 : 12,641,115
0.334 0.666 0.000
rs139338093 lBF = 17.683   Chr16 : 84,778,766
0.332 0.668 0.000
rs35053137 lBF = 12.277   Chr16 : 81,590,859
0.332 0.668 0.000
rs75638798 lBF = 1.42101   Chr16 : 6,504,024
0.329 0.670 0.000
rs117167356 lBF = 12.9266   Chr16 : 50,029,488
0.327 0.673 0.000
rs117073822 lBF = 14.7798   Chr16 : 21,337,217
0.321 0.679 0.000
rs2288017 lBF = 12.487   Chr16 : 84,793,749
0.320 0.679 0.000
rs61744716 lBF = 12.8365   Chr16 : 30,569,349
0.319 0.681 0.000
rs75495766 lBF = 31.5977   Chr16 : 72,693,940
0.318 0.682 0.000
rs9936351 lBF = 16.9967   Chr16 : 6,141,379
0.314 0.685 0.000
rs117096873 lBF = 11.0059   Chr16 : 11,386,960
0.309 0.691 0.000
rs117285773 lBF = 14.3986   Chr16 : 5,628,412
0.307 0.693 0.000
rs1982955 lBF = 7.12195   Chr16 : 76,969,598
0.303 0.697 0.000
rs74934799 lBF = 13.1374   Chr16 : 75,468,490
0.302 0.697 0.000
rs118175001 lBF = 26.7437   Chr16 : 72,724,630
0.301 0.699 0.000
rs4782160 lBF = 13.3659   Chr16 : 14,650,645
0.298 0.702 0.000
rs72805156 lBF = 15.3888   Chr16 : 85,887,242
0.294 0.705 0.000
rs79395151 lBF = 12.3279   Chr16 : 22,272,027
0.271 0.729 0.000
rs76309893 lBF = 21.1949   Chr16 : 13,228,713
0.270 0.729 0.000
rs189013090 lBF = 15.7644   Chr16 : 22,826,046
0.266 0.733 0.000
rs118099348 lBF = 2.12723   Chr16 : 19,435,029
0.264 0.736 0.000
rs77682898 lBF = 24.1144   Chr16 : 26,717,490
0.226 0.773 0.000
rs12051272 lBF = 1.61799   Chr16 : 82,663,288
0.219 0.780 0.000
rs186112291 lBF = 3.93539   Chr16 : 31,213,181
0.208 0.791 0.000
rs1364063 lBF = 14.9508   Chr16 : 69,588,572
0.000 0.797 0.203
rs62043710 lBF = 11.5928   Chr16 : 79,979,067
0.186 0.814 0.000
rs2229288 lBF = 0.309738   Chr16 : 72,828,304
0.180 0.819 0.000
rs9926335 lBF = 6.67192   Chr16 : 56,583,726
0.176 0.823 0.000
rs138642423 lBF = 3.85062   Chr16 : 84,310,399
0.174 0.826 0.000
rs16967753 lBF = 2.08166   Chr16 : 64,635,403
0.158 0.842 0.000
rs75005694 lBF = 15.5513   Chr16 : 28,320,382
0.151 0.849 0.000
rs149808359 lBF = 0.884594   Chr16 : 31,384,127
0.131 0.869 0.000
rs7190458 lBF = 4.70261   Chr16 : 75,263,661
0.001 0.871 0.128
rs7187223 lBF = 13.0009   Chr16 : 82,457,733
0.127 0.873 0.000
rs117530360 lBF = 16.4491   Chr16 : 1,952,972
0.123 0.877 0.000
rs12925700 lBF = 7.5831   Chr16 : 69,793,463
0.000 0.882 0.117
rs770764 lBF = 17.7903   Chr16 : 60,303,723
0.110 0.889 0.000
rs58144239 lBF = 0.2532   Chr16 : 12,759,509
0.105 0.895 0.000
rs145996888 lBF = 5.16769   Chr16 : 31,525,628
0.105 0.895 0.000
rs7202877 lBF = 3.24546   Chr16 : 75,247,245
0.000 0.903 0.097
rs75116029 lBF = 15.377   Chr16 : 13,489,294
0.097 0.903 0.000
rs6500818 lBF = 0.29881   Chr16 : 6,817,375
0.090 0.910 0.000
rs7190199 lBF = 9.04801   Chr16 : 57,101,340
0.085 0.915 0.000
rs62057608 lBF = 5.08013   Chr16 : 34,682,193
0.084 0.916 0.000
rs118022586 lBF = 15.2786   Chr16 : 89,001,840
0.080 0.919 0.000
rs140556148 lBF = 6.77472   Chr16 : 71,346,949
0.078 0.921 0.000
rs17774983 lBF = 12.6669   Chr16 : 89,493,234
0.073 0.926 0.000
rs11641700 lBF = 7.55882   Chr16 : 57,780,381
0.071 0.929 0.000
rs74249525 lBF = 0.18106   Chr16 : 83,447,271
0.064 0.936 0.000
rs889398 lBF = 13.1651   Chr16 : 69,556,715
0.000 0.937 0.062
rs7185320 lBF = 8.98742   Chr16 : 57,101,373
0.061 0.938 0.000
rs139875745 lBF = 0.419107   Chr16 : 31,396,892
0.060 0.940 0.000
rs189794920 lBF = 0.0931077   Chr16 : 2,658,385
0.057 0.942 0.000
rs117602470 lBF = 13.2546   Chr16 : 32,585,912
0.056 0.943 0.000
rs58296637 lBF = 0.139588   Chr16 : 76,463,936
0.050 0.949 0.000
rs11864332 lBF = 0.085269   Chr16 : 12,977,062
0.050 0.950 0.000
rs118155048 lBF = 12.4591   Chr16 : 55,189,457
0.045 0.954 0.000
rs9934540 lBF = 0.137432   Chr16 : 77,876,763
0.041 0.958 0.000
rs75522355 lBF = 12.1753   Chr16 : 6,640,457
0.035 0.965 0.000
rs41321249 lBF = 14.692   Chr16 : 31,341,424
0.034 0.966 0.000
rs77576048 lBF = 9.88924   Chr16 : 90,078,724
0.028 0.971 0.000
rs7205511 lBF = 0.148372   Chr16 : 24,094,703
0.026 0.974 0.000
rs17713676 lBF = 1.1768   Chr16 : 79,073,421
0.024 0.976 0.000
rs2865531 lBF = 5.22883   Chr16 : 75,390,316
0.023 0.976 0.000
rs12929627 lBF = 0.124398   Chr16 : 24,094,977
0.023 0.977 0.000
rs8057849 lBF = 6.81393   Chr16 : 75,443,816
0.000 0.977 0.023
rs6497718 lBF = 0.200184   Chr16 : 24,091,838
0.023 0.977 0.000
rs117458000 lBF = 12.1666   Chr16 : 79,776,544
0.023 0.977 0.000
rs4887818 lBF = 5.72802   Chr16 : 75,361,995
0.000 0.978 0.021
rs11538871 lBF = 14.2251   Chr16 : 89,977,745
0.021 0.979 0.000
rs35420030 lBF = 5.6979   Chr16 : 53,935,407
0.021 0.979 0.000
rs4078023 lBF = 0.103761   Chr16 : 20,320,087
0.020 0.980 0.000
rs11644694 lBF = 7.27682   Chr16 : 58,557,342
0.018 0.981 0.000
rs34289708 lBF = 0.0906836   Chr16 : 24,095,374
0.018 0.982 0.000
rs79358781 lBF = 0.0343247   Chr16 : 80,298,550
0.017 0.982 0.000
rs1303874 lBF = 20.4674   Chr16 : 76,434,865
0.017 0.982 0.000
rs2066847 lBF = 5.18245   Chr16 : 50,763,778
0.017 0.983 0.000
rs150196149 lBF = 8.52422   Chr16 : 90,126,993
0.015 0.984 0.000
rs4150167 lBF = 0.122519   Chr16 : 84,213,684
0.015 0.984 0.000
rs141218390 lBF = 8.40175   Chr16 : 88,501,386
0.015 0.985 0.000
rs35526040 lBF = 0.0915799   Chr16 : 24,093,337
0.015 0.985 0.000
rs190542424 lBF = 2.80667   Chr16 : 34,377,824
0.015 0.985 0.000
rs74635150 lBF = 14.3707   Chr16 : 54,673,627
0.013 0.986 0.000
rs1549306 lBF = 6.97066   Chr16 : 75,415,341
0.000 0.987 0.013
rs11860231 lBF = 5.10285   Chr16 : 75,385,159
0.000 0.987 0.013
rs10782001 lBF = 0.547891   Chr16 : 30,942,625
0.000 0.987 0.013
rs4888383 lBF = 5.39799   Chr16 : 75,386,349
0.000 0.987 0.012
rs11645236 lBF = 19.5773   Chr16 : 54,713,198
0.011 0.988 0.000
rs72802342 lBF = 3.92692   Chr16 : 75,234,872
0.000 0.989 0.011
rs4888372 lBF = 5.09511   Chr16 : 75,313,485
0.000 0.989 0.010
rs11554764 lBF = 7.38931   Chr16 : 72,130,125
0.000 0.990 0.010
rs35942151 lBF = 5.50895   Chr16 : 6,949,523
0.010 0.990 0.000
rs164748 lBF = 2.78549   Chr16 : 89,708,292
0.000 0.990 0.009
rs11642961 lBF = 5.1645   Chr16 : 7,139,435
0.009 0.991 0.000
rs154657 lBF = 2.72053   Chr16 : 89,708,096
0.000 0.991 0.009
rs8050940 lBF = 0.0737519   Chr16 : 62,100,211
0.008 0.992 0.000
rs76653830 lBF = 9.27013   Chr16 : 84,836,091
0.008 0.992 0.000
rs117153386 lBF = 8.12893   Chr16 : 69,634,727
0.008 0.992 0.000
rs71384569 lBF = 6.74754   Chr16 : 50,593,084
0.008 0.992 0.000
rs4389167 lBF = 5.82795   Chr16 : 74,592,132
0.008 0.992 0.000
rs8050059 lBF = 5.00877   Chr16 : 75,388,731
0.000 0.992 0.007
rs79523270 lBF = 9.90193   Chr16 : 88,443,748
0.007 0.993 0.000
rs145049847 lBF = 0.00753444   Chr16 : 22,202,002
0.006 0.994 0.000
rs42471 lBF = 8.92286   Chr16 : 75,480,608
0.006 0.994 0.000
rs7192981 lBF = 9.18729   Chr16 : 75,339,131
0.006 0.994 0.000
rs11248850 lBF = 0.279278   Chr16 : 163,598
0.006 0.994 0.000
rs1121980 lBF = 51.6781   Chr16 : 53,809,247
0.006 0.994 0.000
rs117604355 lBF = 8.1344   Chr16 : 82,276,031
0.006 0.994 0.000
rs12921419 lBF = 0.0356997   Chr16 : 24,089,771
0.005 0.994 0.000
rs37603 lBF = 9.49661   Chr16 : 75,505,567
0.005 0.994 0.000
rs34735233 lBF = 8.29735   Chr16 : 3,993,318
0.005 0.995 0.000
rs154663 lBF = 0.192986   Chr16 : 89,726,035
0.000 0.995 0.005
rs113716969 lBF = 0.0125255   Chr16 : 76,846,266
0.005 0.995 0.000
rs8060598 lBF = 0.44141   Chr16 : 50,781,802
0.004 0.995 0.000
rs9940128 lBF = 50.6204   Chr16 : 53,800,754
0.004 0.996 0.000
rs6624 lBF = 6.43307   Chr16 : 75,327,916
0.000 0.996 0.004
rs8045590 lBF = 6.79603   Chr16 : 6,114,071
0.004 0.996 0.000
rs6499270 lBF = 6.21665   Chr16 : 69,917,740
0.000 0.996 0.003
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0.003 0.997 0.000
rs13708 lBF = 0.663477   Chr16 : 31,000,809
0.000 0.997 0.003
rs4527026 lBF = 0.00365789   Chr16 : 19,960,320
0.002 0.997 0.000
rs2541522 lBF = -0.00790646   Chr16 : 10,750,548
0.003 0.997 0.000
rs11864909 lBF = 14.7652   Chr16 : 20,400,839
0.000 0.997 0.002
rs2301601 lBF = 7.06119   Chr16 : 23,366,528
0.002 0.998 0.000
rs62036855 lBF = 15.9862   Chr16 : 26,232,045
0.002 0.998 0.000
rs34952337 lBF = 5.6582   Chr16 : 66,470,822
0.002 0.998 0.000
rs12445568 lBF = 0.111174   Chr16 : 31,004,812
0.002 0.998 0.000
rs111460975 lBF = 38.1193   Chr16 : 89,434,541
0.000 0.998 0.002
rs9923770 lBF = -0.0160247   Chr16 : 86,139,685
0.002 0.998 0.000
rs192917960 lBF = 0.00220954   Chr16 : 5,919,655
0.002 0.998 0.000
rs1477196 lBF = 7.90626   Chr16 : 53,808,258
0.002 0.998 0.000
rs1805008 lBF = 12.0964   Chr16 : 89,986,144
0.002 0.998 0.000
rs9941349 lBF = 46.4333   Chr16 : 53,825,488
0.002 0.998 0.000
rs5743292 lBF = 9.66373   Chr16 : 50,759,731
0.002 0.998 0.000
rs12926788 lBF = 0.00831407   Chr16 : 24,879,963
0.002 0.998 0.000
rs2080454 lBF = -0.0203477   Chr16 : 49,062,590
0.000 0.998 0.002
rs433598 lBF = -0.0788765   Chr16 : 20,680,206
0.002 0.998 0.000
rs12924903 lBF = 0.447489   Chr16 : 30,928,970
0.000 0.998 0.002
rs5880 lBF = 0.190648   Chr16 : 57,015,091
0.002 0.998 0.000
rs11649653 lBF = 0.70393   Chr16 : 30,918,487
0.000 0.998 0.001
rs1558902 lBF = 52.4011   Chr16 : 53,803,574
0.001 0.998 0.000
rs6500745 lBF = 6.23499   Chr16 : 6,113,694
0.001 0.998 0.000
rs139419280 lBF = 0.00146626   Chr16 : 82,664,833
0.001 0.998 0.000
rs4081947 lBF = -0.057193   Chr16 : 87,579,870
0.000 0.998 0.001
rs117331002 lBF = 5.16067   Chr16 : 34,374,522
0.001 0.998 0.000
rs1421085 lBF = 51.7214   Chr16 : 53,800,954
0.001 0.998 0.000
rs75728418 lBF = 0.00082855   Chr16 : 7,932,578
0.001 0.998 0.000
rs12598815 lBF = 0.013489   Chr16 : 82,848,208
0.001 0.998 0.000
rs17177078 lBF = 0.83584   Chr16 : 24,810,681
0.000 0.999 0.001
rs11865038 lBF = 0.213016   Chr16 : 31,095,171
0.001 0.999 0.000
rs189178161 lBF = 0.00095489   Chr16 : 12,718,853
0.001 0.999 0.000
rs77894924 lBF = 0.00094423   Chr16 : 83,555,020
0.001 0.999 0.000
rs11645002 lBF = -0.0449779   Chr16 : 20,617,841
0.001 0.999 0.000
rs77870048 lBF = 25.4086   Chr16 : 69,965,021
0.000 0.999 0.001
rs16951021 lBF = 0.00072306   Chr16 : 52,321,976
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rs8050136 lBF = 48.0125   Chr16 : 53,816,275
0.000 0.999 0.000
rs17817964 lBF = 47.4145   Chr16 : 53,828,066
0.000 0.999 0.000
Affx-13428745 lBF = 15.6415   Chr16 : 88,783,521
0.000 0.999 0.000
rs9708611 lBF = 11.5019   Chr16 : 52,612,665
0.000 0.999 0.000
rs10048146 lBF = 2.55428   Chr16 : 86,710,660
0.000 0.999 0.000
rs71390846 lBF = 2.1335   Chr16 : 86,714,715
0.000 0.999 0.000
rs10852344 lBF = 0.613469   Chr16 : 12,016,919
0.000 0.999 0.000
rs1967309 lBF = 0.483005   Chr16 : 4,065,583
0.000 0.999 0.000
rs16966142 lBF = 0.410374   Chr16 : 89,851,033
0.000 0.999 0.000
rs8050896 lBF = 0.275154   Chr16 : 66,158,736
0.000 0.999 0.000
rs2925979 lBF = 0.181182   Chr16 : 81,534,790
0.000 0.999 0.000
rs2244613 lBF = 0.167206   Chr16 : 55,844,609
0.000 0.999 0.000
rs1895518 lBF = 0.0972942   Chr16 : 64,904,722
0.000 0.999 0.000
rs16945612 lBF = 0.0662084   Chr16 : 77,428,972
0.000 0.999 0.000
rs117468730 lBF = 0.0194902   Chr16 : 10,205,467
0.000 0.999 0.000
rs11150078 lBF = 0.0169832   Chr16 : 78,466,704
0.000 0.999 0.000
rs17688076 lBF = 0.0139568   Chr16 : 68,286,427
0.000 0.999 0.000
rs79900961 lBF = 0.00797861   Chr16 : 9,297,812
0.000 0.999 0.000
rs4561483 lBF = 0.00633995   Chr16 : 11,920,037
0.000 0.999 0.000
rs77221366 lBF = 0.00438569   Chr16 : 13,111,995
0.000 0.999 0.000
rs117372389 lBF = -0.00759632   Chr16 : 50,668,077
0.000 0.999 0.000
rs7184362 lBF = -0.0147603   Chr16 : 55,879,620
0.000 0.999 0.000
rs17706989 lBF = -0.0157863   Chr16 : 78,569,957
0.000 0.999 0.000
rs12711490 lBF = -0.0313861   Chr16 : 85,973,028
0.000 0.999 0.000
rs1991867 lBF = -0.041253   Chr16 : 82,519,228
0.000 0.999 0.000
rs17291845 lBF = -0.0436244   Chr16 : 55,245,037
0.000 0.999 0.000
rs10083777 lBF = -0.0441441   Chr16 : 81,065,282
0.000 0.999 0.000
rs8056650 lBF = -0.044881   Chr16 : 59,890,698
0.000 0.999 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Cluster X0112
log Bayes Factor = 98.8923
contains 7 variants
0.4262
Cluster X0335
log Bayes Factor = 12.3689
contains 1 variants
0.3403
Cluster X0186
log Bayes Factor = 35.9761
contains 2 variants
0.1776
Cluster X0338
log Bayes Factor = 26.5485
contains 1 variants
0.0650
Variant clusters with highest risk effect

(posterior probability > 0.05)

Cluster X0060
log Bayes Factor = 242.413
contains 5 variants
0.7912
Cluster X0209
log Bayes Factor = 214.798
contains 8 variants
0.6865
Cluster X0321
log Bayes Factor = 162.562
contains 1 variants
0.6054
Cluster X0100
log Bayes Factor = 730.252
contains 26 variants
0.5951
Cluster X0083
log Bayes Factor = 351.917
contains 13 variants
0.5806
Cluster X0123
log Bayes Factor = 382.779
contains 14 variants
0.5785
Cluster X0084
log Bayes Factor = 433.078
contains 21 variants
0.5715
Cluster X0079
log Bayes Factor = 413.803
contains 22 variants
0.5668
Cluster X0326
log Bayes Factor = 112.92
contains 5 variants
0.5520
Cluster X0080
log Bayes Factor = 455.123
contains 21 variants
0.5518
Cluster X0250
log Bayes Factor = 43.399
contains 4 variants
0.5517
Cluster X0064
log Bayes Factor = 166.06
contains 10 variants
0.5488
Cluster X0141
log Bayes Factor = 742.063
contains 30 variants
0.5243
Cluster X0261
log Bayes Factor = 420.614
contains 20 variants
0.5140
Cluster X0277
log Bayes Factor = 726.213
contains 23 variants
0.5140
Cluster X0086
log Bayes Factor = 131.002
contains 8 variants
0.5140
Cluster X0087
log Bayes Factor = 894.58
contains 26 variants
0.5140
Cluster X0024
log Bayes Factor = 309.44
contains 13 variants
0.5140
Cluster X0057
log Bayes Factor = 439.35
contains 16 variants
0.5140
Cluster X0171
log Bayes Factor = 291.293
contains 14 variants
0.5140
Cluster X0140
log Bayes Factor = 164.536
contains 8 variants
0.5140
Cluster X0188
log Bayes Factor = 222.629
contains 14 variants
0.5140
Cluster X0271
log Bayes Factor = 256.743
contains 10 variants
0.5140
Cluster X0146
log Bayes Factor = 686.343
contains 22 variants
0.5140
Cluster X0072
log Bayes Factor = 1189.98
contains 37 variants
0.5140
Cluster X0170
log Bayes Factor = 264.081
contains 11 variants
0.5140
Cluster X0222
log Bayes Factor = 431.582
contains 17 variants
0.5140
Cluster X0122
log Bayes Factor = 219.114
contains 9 variants
0.5139
Cluster X0094
log Bayes Factor = 562.956
contains 18 variants
0.5139
Cluster X0177
log Bayes Factor = 254.872
contains 10 variants
0.5139
Cluster X0044
log Bayes Factor = 1165.44
contains 34 variants
0.5139
Cluster X0091
log Bayes Factor = 303.64
contains 12 variants
0.5139
Cluster X0032
log Bayes Factor = 255.737
contains 12 variants
0.5139
Cluster X0049
log Bayes Factor = 597.061
contains 18 variants
0.5138
Cluster X0075
log Bayes Factor = 431.344
contains 16 variants
0.5138
Cluster X0280
log Bayes Factor = 86.0876
contains 1 variants
0.5138
Cluster X0085
log Bayes Factor = 138.902
contains 6 variants
0.5138
Cluster X0232
log Bayes Factor = 695.273
contains 23 variants
0.5138
Cluster X0257
log Bayes Factor = 281.184
contains 10 variants
0.5138
Cluster X0073
log Bayes Factor = 785.614
contains 25 variants
0.5137
Cluster X0045
log Bayes Factor = 446.264
contains 16 variants
0.5137
Cluster X0055
log Bayes Factor = 274.911
contains 10 variants
0.5137
Cluster X0043
log Bayes Factor = 517.108
contains 20 variants
0.5137
Cluster X0020
log Bayes Factor = 557.721
contains 18 variants
0.5136
Cluster X0093
log Bayes Factor = 289.878
contains 10 variants
0.5136
Cluster X0109
log Bayes Factor = 257.685
contains 11 variants
0.5135
Cluster X0224
log Bayes Factor = 278.692
contains 11 variants
0.5135
Cluster X0197
log Bayes Factor = 158.582
contains 8 variants
0.5134
Cluster X0051
log Bayes Factor = 376.793
contains 14 variants
0.5134
Cluster X0145
log Bayes Factor = 274.587
contains 11 variants
0.5134
Cluster X0258
log Bayes Factor = 104.851
contains 6 variants
0.5133
Cluster X0205
log Bayes Factor = 674.183
contains 18 variants
0.5132
Cluster X0098
log Bayes Factor = 246.226
contains 8 variants
0.5131
Cluster X0227
log Bayes Factor = 249.287
contains 11 variants
0.5131
Cluster X0007
log Bayes Factor = 107.567
contains 7 variants
0.5130
Cluster X0150
log Bayes Factor = 861.091
contains 26 variants
0.5128
Cluster X0166
log Bayes Factor = 230.746
contains 8 variants
0.5128
Cluster X0039
log Bayes Factor = 463.231
contains 17 variants
0.5127
Cluster X0246
log Bayes Factor = 121.08
contains 5 variants
0.5127
Cluster X0124
log Bayes Factor = 336.468
contains 13 variants
0.5126
Cluster X0153
log Bayes Factor = 328.394
contains 11 variants
0.5126
Cluster X0192
log Bayes Factor = 402.511
contains 14 variants
0.5126
Cluster X0203
log Bayes Factor = 363.522
contains 11 variants
0.5126
Cluster X0042
log Bayes Factor = 307.243
contains 12 variants
0.5125
Cluster X0164
log Bayes Factor = 463.793
contains 16 variants
0.5124
Cluster X0174
log Bayes Factor = 214.209
contains 8 variants
0.5123
Cluster X0003
log Bayes Factor = 195.6
contains 8 variants
0.5122
Cluster X0028
log Bayes Factor = 120.445
contains 7 variants
0.5119
Cluster X0059
log Bayes Factor = 922.497
contains 26 variants
0.5119
Cluster X0161
log Bayes Factor = 609.219
contains 20 variants
0.5115
Cluster X0220
log Bayes Factor = 142.284
contains 7 variants
0.5112
Cluster X0143
log Bayes Factor = 179.808
contains 8 variants
0.5109
Cluster X0249
log Bayes Factor = 244.457
contains 11 variants
0.5102
Cluster X0284
log Bayes Factor = 192.532
contains 9 variants
0.5100
Cluster X0155
log Bayes Factor = 348.568
contains 12 variants
0.5096
Cluster X0078
log Bayes Factor = 203.49
contains 11 variants
0.5095
Cluster X0240
log Bayes Factor = 104.862
contains 6 variants
0.5088
Cluster X0026
log Bayes Factor = 232.119
contains 9 variants
0.5088
Cluster X0077
log Bayes Factor = 571.533
contains 17 variants
0.5086
Cluster X0053
log Bayes Factor = 218.825
contains 12 variants
0.5081
Cluster X0182
log Bayes Factor = 91.4459
contains 4 variants
0.5080
Cluster X0005
log Bayes Factor = 282.915
contains 11 variants
0.5070
Cluster X0139
log Bayes Factor = 304.555
contains 10 variants
0.5064
Cluster X0069
log Bayes Factor = 519.392
contains 20 variants
0.5055
Cluster X0181
log Bayes Factor = 141.396
contains 6 variants
0.5054
Cluster X0201
log Bayes Factor = 368.049
contains 13 variants
0.5054
Cluster X0074
log Bayes Factor = 353.38
contains 15 variants
0.5054
Cluster X0106
log Bayes Factor = 980.916
contains 30 variants
0.5052
Cluster X0129
log Bayes Factor = 195.809
contains 7 variants
0.5052
Cluster X0253
log Bayes Factor = 331.491
contains 13 variants
0.5042
Cluster X0221
log Bayes Factor = 149.378
contains 10 variants
0.5040
Cluster X0088
log Bayes Factor = 243.609
contains 9 variants
0.5035
Cluster X0256
log Bayes Factor = 211.588
contains 9 variants
0.5032
Cluster X0111
log Bayes Factor = 403.183
contains 18 variants
0.5032
Cluster X0052
log Bayes Factor = 654.387
contains 25 variants
0.5028
Cluster X0165
log Bayes Factor = 303.727
contains 12 variants
0.5018
Cluster X0210
log Bayes Factor = 426.159
contains 17 variants
0.5003
Cluster X0290
log Bayes Factor = 333.908
contains 13 variants
0.4982
Cluster X0110
log Bayes Factor = 721.325
contains 13 variants
0.4963
Cluster X0243
log Bayes Factor = 104.974
contains 6 variants
0.4958
Cluster X0037
log Bayes Factor = 171.712
contains 6 variants
0.4950
Cluster X0237
log Bayes Factor = 123.902
contains 6 variants
0.4947
Cluster X0082
log Bayes Factor = 496.905
contains 17 variants
0.4945
Cluster X0189
log Bayes Factor = 149.681
contains 5 variants
0.4942
Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants
0.4939
Cluster X0142
log Bayes Factor = 295.63
contains 12 variants
0.4937
Cluster X0180
log Bayes Factor = 410.88
contains 15 variants
0.4932
Cluster X0176
log Bayes Factor = 407.797
contains 14 variants
0.4930
Cluster X0156
log Bayes Factor = 226.954
contains 9 variants
0.4908
Cluster X0012
log Bayes Factor = 112.432
contains 5 variants
0.4900
Cluster X0212
log Bayes Factor = 300.777
contains 10 variants
0.4898
Cluster X0040
log Bayes Factor = 542.747
contains 16 variants
0.4891
Cluster X0226
log Bayes Factor = 145.726
contains 8 variants
0.4890
Cluster X0021
log Bayes Factor = 338.631
contains 13 variants
0.4883
Cluster X0167
log Bayes Factor = 136.48
contains 6 variants
0.4878
Cluster X0248
log Bayes Factor = 254.854
contains 10 variants
0.4868
Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants
0.4848
Cluster X0071
log Bayes Factor = 131.269
contains 6 variants
0.4844
Cluster X0214
log Bayes Factor = 186.582
contains 8 variants
0.4840
Cluster X0019
log Bayes Factor = 372.36
contains 16 variants
0.4838
Cluster X0231
log Bayes Factor = 82.3185
contains 5 variants
0.4829
Cluster X0293
log Bayes Factor = 169.051
contains 7 variants
0.4822
Cluster X0041
log Bayes Factor = 306.192
contains 14 variants
0.4773
Cluster X0275
log Bayes Factor = 219.726
contains 10 variants
0.4763
Cluster X0238
log Bayes Factor = 97.9307
contains 4 variants
0.4761
Cluster X0046
log Bayes Factor = 387.972
contains 16 variants
0.4759
Cluster X0081
log Bayes Factor = 278.568
contains 10 variants
0.4751
Cluster X0178
log Bayes Factor = 225.6
contains 9 variants
0.4750
Cluster X0070
log Bayes Factor = 421.182
contains 15 variants
0.4748
Cluster X0274
log Bayes Factor = 454.783
contains 18 variants
0.4744
Cluster X0119
log Bayes Factor = 114.358
contains 6 variants
0.4712
Cluster X0089
log Bayes Factor = 308.747
contains 13 variants
0.4710
Cluster X0213
log Bayes Factor = 405.918
contains 15 variants
0.4681
Cluster X0133
log Bayes Factor = 224.204
contains 11 variants
0.4668
Cluster X0327
log Bayes Factor = 118.248
contains 3 variants
0.4663
Cluster X0058
log Bayes Factor = 183.199
contains 8 variants
0.4654
Cluster X0194
log Bayes Factor = 189.9
contains 5 variants
0.4644
Cluster X0297
log Bayes Factor = 63.8292
contains 4 variants
0.4613
Cluster X0218
log Bayes Factor = 425.579
contains 18 variants
0.4503
Cluster X0157
log Bayes Factor = 172.957
contains 8 variants
0.4494
Cluster X0029
log Bayes Factor = 709.102
contains 23 variants
0.4492
Cluster X0134
log Bayes Factor = 151.731
contains 8 variants
0.4322
Cluster X0050
log Bayes Factor = 397.79
contains 16 variants
0.4316
Cluster X0038
log Bayes Factor = 31.1234
contains 2 variants
0.4238
Cluster X0337
log Bayes Factor = 84.9395
contains 2 variants
0.4226
Cluster X0339
log Bayes Factor = 56.078
contains 2 variants
0.4225
Cluster X0268
log Bayes Factor = 213.591
contains 8 variants
0.4220
Cluster X0118
log Bayes Factor = 91.1908
contains 5 variants
0.4187
Cluster X0033
log Bayes Factor = 379.444
contains 13 variants
0.4071
Cluster X0163
log Bayes Factor = 122.554
contains 6 variants
0.4071
Cluster X0014
log Bayes Factor = 131.677
contains 6 variants
0.4068
Cluster X0047
log Bayes Factor = 378.621
contains 14 variants
0.4045
Cluster X0294
log Bayes Factor = 25.2869
contains 2 variants
0.4045
Cluster X0076
log Bayes Factor = 310.928
contains 15 variants
0.4027
Cluster X0001
log Bayes Factor = 167.541
contains 7 variants
0.3962
Cluster X0137
log Bayes Factor = 120.748
contains 4 variants
0.3932
Cluster X0229
log Bayes Factor = 347.165
contains 13 variants
0.3829
Cluster X0054
log Bayes Factor = 197.338
contains 9 variants
0.3796
Cluster X0015
log Bayes Factor = 356.23
contains 15 variants
0.3787
Cluster X0067
log Bayes Factor = 179.381
contains 8 variants
0.3695
Cluster X0132
log Bayes Factor = 267.393
contains 11 variants
0.3673
Cluster X0126
log Bayes Factor = 384.432
contains 15 variants
0.3657
Cluster X0259
log Bayes Factor = 246.237
contains 11 variants
0.3603
Cluster X0107
log Bayes Factor = 151.016
contains 1 variants
0.3581
Cluster X0191
log Bayes Factor = 163.555
contains 8 variants
0.3561
Cluster X0330
log Bayes Factor = 183.455
contains 2 variants
0.3492
Cluster X0287
log Bayes Factor = 33.3095
contains 4 variants
0.3485
Cluster X0263
log Bayes Factor = 240.36
contains 13 variants
0.3428
Cluster X0264
log Bayes Factor = 205.833
contains 10 variants
0.3374
Cluster X0307
log Bayes Factor = 826.86
contains 2 variants
0.3344
Cluster X0148
log Bayes Factor = 315.237
contains 11 variants
0.3254
Cluster X0204
log Bayes Factor = 169.796
contains 8 variants
0.3165
Cluster X0030
log Bayes Factor = 216.364
contains 9 variants
0.3157
Cluster X0184
log Bayes Factor = 188.416
contains 8 variants
0.3133
Cluster X0152
log Bayes Factor = 331.156
contains 10 variants
0.3126
Cluster X0063
log Bayes Factor = 107.557
contains 5 variants
0.3043
Cluster X0018
log Bayes Factor = 430.611
contains 18 variants
0.3025
Cluster X0236
log Bayes Factor = 83.9265
contains 3 variants
0.3012
Cluster X0154
log Bayes Factor = 282.084
contains 12 variants
0.2986
Cluster X0048
log Bayes Factor = 358.819
contains 19 variants
0.2834
Cluster X0320
log Bayes Factor = 110.964
contains 6 variants
0.2829
Cluster X0159
log Bayes Factor = 152.327
contains 7 variants
0.2788
Cluster X0283
log Bayes Factor = 162.98
contains 9 variants
0.2696
Cluster X0138
log Bayes Factor = 43.7891
contains 4 variants
0.2638
Cluster X0162
log Bayes Factor = 144.479
contains 9 variants
0.2619
Cluster X0068
log Bayes Factor = 127.774
contains 6 variants
0.2608
Cluster X0322
log Bayes Factor = 70.0115
contains 3 variants
0.2545
Cluster X0117
log Bayes Factor = 453.246
contains 21 variants
0.2483
Cluster X0276
log Bayes Factor = 187.108
contains 9 variants
0.2472
Cluster X0095
log Bayes Factor = 179.348
contains 8 variants
0.2339
Cluster X0120
log Bayes Factor = 79.6695
contains 4 variants
0.2176
Cluster X0061
log Bayes Factor = 293.105
contains 15 variants
0.2175
Cluster X0332
log Bayes Factor = 65.2374
contains 3 variants
0.2126
Cluster X0324
log Bayes Factor = 32.1341
contains 1 variants
0.1990
Cluster X0121
log Bayes Factor = 131.08
contains 9 variants
0.1933
Cluster X0131
log Bayes Factor = 143.942
contains 8 variants
0.1913
Cluster X0185
log Bayes Factor = 84.7127
contains 6 variants
0.1715
Cluster X0013
log Bayes Factor = 548.265
contains 23 variants
0.1488
Cluster X0169
log Bayes Factor = 331.98
contains 16 variants
0.1050
Cluster X0114
log Bayes Factor = 510.917
contains 25 variants
0.0703
Cluster X0262
log Bayes Factor = 269.713
contains 9 variants
0.0532
 
 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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