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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35053137
log Bayes Factor = 12.277
Chromosome 16   position 81,590,859  (GRCh37) Explore rs35053137 on Ensembl!
Variant rs35053137 is part of Cluster X0185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I84 Haemorrhoids
0.999 0.001 0.000
K70-K77 Diseases of liver
0.992 0.008 0.000
N60-N64 Disorders of breast
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
K58 Irritable bowel syndrome
0.990 0.010 0.000
S20-S29 Injuries to the thorax
0.987 0.013 0.000
K57 Diverticular disease of intestine
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
I35 Nonrheumatic aortic valve disorders
0.984 0.016 0.000
N64 Other disorders of breast
0.982 0.018 0.000
N60 Benign mammary dysplasia
0.980 0.020 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.979 0.021 0.000
N10-N16 Renal tubulo-interstitial diseases
0.977 0.023 0.000
I84.8 Unspecified haemorrhoids with other complications
0.976 0.024 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.976 0.024 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.976 0.024 0.000
K59 Other functional intestinal disorders
0.975 0.025 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.972 0.028 0.000
N64.5 Other signs and symptoms in breast
0.972 0.028 0.000
N13 Obstructive and reflux uropathy
0.969 0.031 0.000
I35.0 Aortic (valve) stenosis
0.968 0.032 0.000
I10-I15 Hypertensive diseases
0.956 0.044 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.954 0.046 0.000
Chapter I Certain infectious and parasitic diseases
0.950 0.050 0.000
K90-K93 Other diseases of the digestive system
0.945 0.055 0.000
K76 Other diseases of liver
0.944 0.056 0.000
I10 Essential (primary) hypertension
0.943 0.057 0.000
S27 Injury of other and unspecified intrathoracic organs
0.943 0.057 0.000
I84.2 Internal haemorrhoids without complication
0.935 0.065 0.000
I84.1 Internal haemorrhoids with other complications
0.928 0.072 0.000
N62 Hypertrophy of breast
0.926 0.074 0.000
K59.0 Constipation
0.926 0.074 0.000
M40-M43 Deforming dorsopathies
0.922 0.078 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.922 0.078 0.000
I44 Atrioventricular and left bundle-branch block
0.921 0.079 0.000
I86 Varicose veins of other sites
0.920 0.080 0.000
I38 Endocarditis, valve unspecified
0.912 0.088 0.000
N60.2 Fibroadenosis of breast
0.911 0.089 0.000
N13.3 Other and unspecified hydronephrosis
0.901 0.099 0.000
N60.1 Diffuse cystic mastopathy
0.899 0.101 0.000
K92 Other diseases of digestive system
0.898 0.102 0.000
I30 Acute pericarditis
0.898 0.102 0.000
I20-I25 Ischaemic heart diseases
0.898 0.102 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.898 0.102 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.896 0.104 0.000
K55 Vascular disorders of intestine
0.896 0.104 0.000
K75 Other inflammatory liver diseases
0.894 0.106 0.000
I42 Cardiomyopathy
0.894 0.106 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
K62 Other diseases of anus and rectum
0.888 0.112 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.881 0.119 0.000
I45 Other conduction disorders
0.880 0.120 0.000
I51 Complications and ill-defined descriptions of heart disease
0.879 0.121 0.000
K92.0 Haematemesis
0.877 0.123 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.877 0.123 0.000
K76.9 Liver disease, unspecified
0.877 0.123 0.000
N13.4 Hydroureter
0.874 0.126 0.000
N60.3 Fibrosclerosis of breast
0.874 0.126 0.000
M43 Other deforming dorsopathies
0.874 0.126 0.000
I84.6 Residual haemorrhoidal skin tags
0.873 0.127 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.872 0.128 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
I50 Heart failure
0.867 0.133 0.000
C15-C26 Malignant neoplasms of digestive organs
0.867 0.133 0.000
Chapter II Neoplasms
0.866 0.134 0.000
I22 Subsequent myocardial infarction
0.864 0.136 0.000
M65-M68 Disorders of synovium and tendon
0.864 0.136 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.863 0.137 0.000
K70 Alcoholic liver disease
0.859 0.141 0.000
M50-M54 Other dorsopathies
0.855 0.145 0.000
C16 Malignant neoplasm of stomach
0.854 0.146 0.000
S20 Superficial injury of thorax
0.853 0.147 0.000
M20-M25 Other joint disorders
0.852 0.148 0.000
N13.8 Other obstructive and reflux uropathy
0.852 0.148 0.000
T66-T78 Other and unspecified effects of external causes
0.852 0.148 0.000
K62.5 Haemorrhage of anus and rectum
0.851 0.149 0.000
I84.3 External thrombosed haemorrhoids
0.851 0.149 0.000
M24 Other specific joint derangements
0.848 0.152 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.846 0.154 0.000
B95-B98 Bacterial, viral and other infectious agents
0.845 0.155 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.844 0.156 0.000
S60-S69 Injuries to the wrist and hand
0.839 0.161 0.000
M43.1 Spondylolisthesis
0.839 0.161 0.000
M24.1 Other articular cartilage disorders
0.835 0.165 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.830 0.170 0.000
K65-K67 Diseases of peritoneum
0.828 0.172 0.000
K55.2 Angiodysplasia of colon
0.827 0.173 0.000
C16.9 Stomach, unspecified
0.827 0.173 0.000
I30.9 Acute pericarditis, unspecified
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.823 0.177 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.816 0.184 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.815 0.185 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.814 0.186 0.000
N64.8 Other specified disorders of breast
0.813 0.187 0.000
K76.7 Hepatorenal syndrome
0.813 0.187 0.000
I44.2 Atrioventricular block, complete
0.812 0.188 0.000
N64.1 Fat necrosis of breast
0.811 0.189 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.810 0.190 0.000
S27.0 Traumatic pneumothorax
0.810 0.190 0.000
S27.1 Traumatic haemothorax
0.810 0.190 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.807 0.193 0.000
B35-B49 Mycoses
0.807 0.193 0.000
K72 Hepatic failure, not elsewhere classified
0.805 0.195 0.000
K75.8 Other specified inflammatory liver diseases
0.805 0.195 0.000
K63 Other diseases of intestine
0.804 0.196 0.000
I44.7 Left bundle-branch block, unspecified
0.803 0.197 0.000
K59.1 Functional diarrhoea
0.803 0.197 0.000
M91-M94 Chondropathies
0.801 0.199 0.000
K62.6 Ulcer of anus and rectum
0.800 0.200 0.000
I86.4 Gastric varices
0.799 0.201 0.000
I86.1 Scrotal varices
0.799 0.201 0.000
I50.1 Left ventricular failure
0.799 0.201 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.798 0.202 0.000
S22.4 Multiple fractures of ribs
0.795 0.204 0.000
K59.9 Functional intestinal disorder, unspecified
0.794 0.206 0.000
B25-B34 Other viral diseases
0.792 0.208 0.000
I42.2 Other hypertrophic cardiomyopathy
0.792 0.208 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.791 0.209 0.000
I80 Phlebitis and thrombophlebitis
0.790 0.210 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.788 0.212 0.000
I35.8 Other aortic valve disorders
0.788 0.212 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.784 0.216 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.784 0.216 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.783 0.217 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.783 0.217 0.000
I45.3 Trifascicular block
0.782 0.218 0.000
N10 Acute tubulo-interstitial nephritis
0.782 0.218 0.000
G90-G99 Other disorders of the nervous system
0.781 0.219 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.781 0.219 0.000
M51 Other intervertebral disk disorders
0.781 0.219 0.000
N60.0 Solitary cyst of breast
0.780 0.220 0.000
G62 Other polyneuropathies
0.780 0.220 0.000
O60-O75 Complications of labour and delivery
0.780 0.220 0.000
I51.7 Cardiomegaly
0.776 0.224 0.000
Q60-Q64 Congenital malformations of the urinary system
0.776 0.224 0.000
I20 Angina pectoris
0.774 0.226 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
I87 Other disorders of veins
0.771 0.229 0.000
I51.8 Other ill-defined heart diseases
0.771 0.229 0.000
T82.1 Mechanical complication of cardiac electronic device
0.770 0.230 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.770 0.230 0.000
K59.3 Megacolon, not elsewhere classified
0.769 0.231 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
I36 Nonrheumatic tricuspid valve disorders
0.767 0.233 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.767 0.233 0.000
S27.2 Traumatic heamopneumothorax
0.763 0.237 0.000
M60-M63 Disorders of muscles
0.762 0.238 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.762 0.238 0.000
I85 Oesophageal varices
0.761 0.239 0.000
I42.6 Alcoholic cardiomyopathy
0.761 0.239 0.000
M24.2 Disorder of ligament
0.760 0.239 0.000
N60.4 Mammary duct ectasia
0.760 0.240 0.000
I84.9 Unspecified haemorrhoids without complication
0.759 0.241 0.000
K59.4 Anal spasm
0.756 0.244 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.756 0.244 0.000
S60 Superficial injury of wrist and hand
0.755 0.245 0.000
S27.3 Other injuries of lung
0.752 0.248 0.000
K65 Peritonitis
0.751 0.249 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.749 0.251 0.000
I50.9 Heart failure, unspecified
0.746 0.254 0.000
T78 Adverse effects, not elsewhere classified
0.746 0.254 0.000
M65 Synovitis and tenosynovitis
0.745 0.255 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.744 0.256 0.000
N99-N99 Other disorders of the genitourinary system
0.743 0.257 0.000
K76.6 Portal hypertension
0.743 0.257 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.742 0.258 0.000
K62.4 Stenosis of anus and rectum
0.741 0.259 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.740 0.260 0.000
T87 Complications peculiar to reattachment and amputation
0.740 0.260 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.739 0.261 0.000
I35.9 Aortic valve disorder, unspecified
0.739 0.261 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.739 0.261 0.000
B65-B83 Helminthiases
0.739 0.261 0.000
M51.2 Other specified intervertebral disk displacement
0.737 0.263 0.000
K73 Chronic hepatitis, not elsewhere classified
0.737 0.263 0.000
K90 Intestinal malabsorption
0.736 0.264 0.000
I88 Nonspecific lymphadenitis
0.735 0.264 0.000
I82 Other venous embolism and thrombosis
0.735 0.265 0.000
O80-O84 Delivery
0.735 0.265 0.000
S22.40 Multiple fractures of ribs (closed)
0.735 0.265 0.000
I31 Other diseases of pericardium
0.734 0.266 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.732 0.268 0.000
I45.2 Bifascicular block
0.731 0.269 0.000
A65-A69 Other spirochaetal diseases
0.731 0.269 0.000
K63.5 Polyp of colon
0.730 0.270 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.730 0.270 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.729 0.271 0.000
B37 Candidiasis
0.729 0.271 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.728 0.272 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.727 0.273 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.725 0.275 0.000
I44.1 Atrioventricular block, second degree
0.724 0.276 0.000
G62.8 Other specified polyneuropathies
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.722 0.278 0.000
I20.8 Other forms of angina pectoris
0.721 0.279 0.000
B50-B64 Protozoal diseases
0.721 0.279 0.000
C21 Malignant neoplasm of anus and anal canal
0.721 0.279 0.000
S70-S79 Injuries to the hip and thigh
0.719 0.281 0.000
K76.8 Other specified diseases of liver
0.719 0.281 0.000
M41 Scoliosis
0.719 0.281 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.718 0.281 0.000
I45.4 Nonspecific intraventricular block
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Q61 Cystic kidney disease
0.716 0.284 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.715 0.285 0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.715 0.285 0.000
N11 Chronic tubulo-interstitial nephritis
0.715 0.285 0.000
I81 Portal vein thrombosis
0.714 0.285 0.000
C23 Malignant neoplasm of gallbladder
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.711 0.289 0.000
K71 Toxic liver disease
0.711 0.289 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.710 0.290 0.000
O16 Unspecified maternal hypertension
0.708 0.292 0.000
C16.0 Cardia
0.708 0.292 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.708 0.292 0.000
S26 Injury of heart
0.708 0.292 0.000
S25 Injury of blood vessels of thorax
0.708 0.292 0.000
S24 Injury of nerves and spinal cord at thorax level
0.708 0.292 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.708 0.292 0.000
S21 Open wound of thorax
0.708 0.292 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.708 0.292 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.707 0.293 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.707 0.293 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.707 0.293 0.000
K92.1 Melaena
0.706 0.294 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
S22.0 Fracture of thoracic vertebra
0.704 0.296 0.000
K62.7 Radiation proctitis
0.704 0.296 0.000
N64.3 Galactorrhoea not associated with childbirth
0.704 0.296 0.000
N64.2 Atrophy of breast
0.704 0.296 0.000
N64.0 Fissure and fistula of nipple
0.704 0.296 0.000
N13.6 Pyonephrosis
0.703 0.297 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.703 0.297 0.000
N60.9 Benign mammary dysplasia, unspecified
0.703 0.297 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
K55.1 Chronic vascular disorders of intestine
0.702 0.298 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.702 0.298 0.000
K92.8 Other specified diseases of digestive system
0.701 0.299 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
S10 Superficial injury of neck
0.700 0.300 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.700 0.300 0.000
N15 Other renal tubulo-interstitial diseases
0.700 0.300 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.700 0.300 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.700 0.300 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.700 0.300 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.700 0.300 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.699 0.300 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
C16.6 Greater curvature of stomach, unspecified
0.699 0.301 0.000
M67 Other disorders of synovium and tendon
0.699 0.301 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.699 0.301 0.000
K62.2 Anal prolapse
0.699 0.301 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.698 0.302 0.000
K75.4 Autoimmune hepatitis
0.698 0.302 0.000
S29 Other and unspecified injuries of thorax
0.696 0.304 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.696 0.304 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.694 0.305 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.693 0.307 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.691 0.309 0.000
G70-G73 Diseases of myoneural junction and muscle
0.690 0.310 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.689 0.311 0.000
M24.23 Disorder of ligament (Forearm)
0.689 0.311 0.000
C25 Malignant neoplasm of pancreas
0.688 0.312 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.686 0.314 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.686 0.314 0.000
I13 Hypertensive heart and renal disease
0.686 0.314 0.000
N25-N29 Other disorders of kidney and ureter
0.685 0.315 0.000
G62.9 Polyneuropathy, unspecified
0.684 0.316 0.000
K70.9 Alcoholic liver disease, unspecified
0.683 0.317 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.683 0.317 0.000
T79-T79 Certain early complications of trauma
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.681 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.681 0.318 0.000
A75-A79 Rickettsioses
0.681 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.681 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.681 0.318 0.000
A15-A19 Tuberculosis
0.681 0.318 0.000
K70.1 Alcoholic hepatitis
0.681 0.319 0.000
D68 Other coagulation defects
0.681 0.319 0.000
T88.5 Other complications of anaesthesia
0.681 0.319 0.000
I20.1 Angina pectoris with documented spasm
0.680 0.320 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
K62.9 Disease of anus and rectum, unspecified
0.679 0.321 0.000
I15 Secondary hypertension
0.679 0.321 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.677 0.322 0.000
K76.5 Hepatic veno-occlusive disease
0.677 0.323 0.000
K76.4 Peliosis hepatis
0.677 0.323 0.000
K76.3 Infarction of liver
0.677 0.323 0.000
K76.2 Central haemorrhagic necrosis of liver
0.677 0.323 0.000
K76.1 Chronic passive congestion of liver
0.677 0.323 0.000
M34 Systemic sclerosis
0.676 0.324 0.000
S27.9 Injury of unspecified intrathoracic organ
0.676 0.324 0.000
S27.8 Injury of other specified intrathoracic organs
0.676 0.324 0.000
S27.7 Multiple injuries of intrathoracic organs
0.676 0.324 0.000
S27.6 Injury of pleura
0.676 0.324 0.000
S27.5 Injury of thoracic trachea
0.676 0.324 0.000
S27.4 Injury of bronchus
0.676 0.324 0.000
S36 Injury of intra-abdominal organs
0.676 0.324 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
D69 Purpura and other haemorrhagic conditions
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
I84.5 External haemorrhoids without complication
0.674 0.326 0.000
O72 Postpartum haemorrhage
0.674 0.326 0.000
T88.4 Failed or difficult intubation
0.673 0.327 0.000
S90-S99 Injuries to the ankle and foot
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
K70.4 Alcoholic hepatic failure
0.671 0.329 0.000
K72.9 Hepatic failure, unspecified
0.671 0.329 0.000
C15 Malignant neoplasm of oesophagus
0.670 0.330 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.669 0.331 0.000
K92.9 Disease of digestive system, unspecified
0.667 0.333 0.000
T78.4 Allergy, unspecified
0.666 0.334 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.665 0.335 0.000
I44.6 Other and unspecified fascicular block
0.664 0.335 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.664 0.336 0.000
C17 Malignant neoplasm of small intestine
0.664 0.336 0.000
N64.4 Mastodynia
0.664 0.336 0.000
C22.9 Liver, unspecified
0.663 0.337 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.662 0.338 0.000
I45.8 Other specified conduction disorders
0.662 0.338 0.000
M42 Spinal osteochondrosis
0.661 0.339 0.000
M40 Kyphosis and lordosis
0.661 0.339 0.000
S22.1 Multiple fractures of thoracic spine
0.661 0.339 0.000
K74 Fibrosis and cirrhosis of liver
0.661 0.339 0.000
I87.1 Compression of vein
0.660 0.340 0.000
S67 Crushing injury of wrist and hand
0.660 0.340 0.000
I44.5 Left posterior fascicular block
0.660 0.340 0.000
I44.4 Left anterior fascicular block
0.660 0.340 0.000
I86.3 Vulval varices
0.659 0.340 0.000
I86.2 Pelvic varices
0.659 0.340 0.000
I86.0 Sublingual varices
0.659 0.340 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.659 0.341 0.000
I33 Acute and subacute endocarditis
0.658 0.341 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.657 0.343 0.000
O85-O92 Complications predominantly related to the puerperium
0.656 0.344 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.655 0.345 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.655 0.345 0.000
I86.8 Varicose veins of other specified sites
0.654 0.345 0.000
I34 Nonrheumatic mitral valve disorders
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.346 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.653 0.347 0.000
G90 Disorders of autonomic nervous system
0.652 0.348 0.000
I42.0 Dilated cardiomyopathy
0.652 0.348 0.000
O82 Single delivery by Caesarean section
0.652 0.348 0.000
K75.9 Inflammatory liver disease, unspecified
0.651 0.349 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.651 0.349 0.000
A80-A89 Viral infections of the central nervous system
0.650 0.349 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.650 0.349 0.000
K61 Abscess of anal and rectal regions
0.650 0.350 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.650 0.350 0.000
K65.8 Other peritonitis
0.649 0.351 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.647 0.353 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.645 0.354 0.000
S80-S89 Injuries to the knee and lower leg
0.645 0.355 0.000
C16.5 Lesser curvature of stomach, unspecified
0.645 0.355 0.000
I05-I09 Chronic rheumatic heart diseases
0.645 0.355 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.644 0.355 0.000
I30.8 Other forms of acute pericarditis
0.644 0.356 0.000
I30.1 Infective pericarditis
0.644 0.356 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.644 0.356 0.000
I23 Certain current complications following acute myocardial infarction
0.644 0.356 0.000
T88.9 Complication of surgical and medical care, unspecified
0.644 0.356 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.644 0.356 0.000
T88.2 Shock due to anaesthesia
0.644 0.356 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.644 0.356 0.000
T88.0 Infection following immunisation
0.644 0.356 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.643 0.357 0.000
I35.1 Aortic (valve) insufficiency
0.643 0.357 0.000
K70.3 Alcoholic cirrhosis of liver
0.643 0.357 0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.642 0.357 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.642 0.357 0.000
T80.6 Other serum reactions
0.642 0.357 0.000
T80.5 Anaphylactic shock due to serum
0.642 0.357 0.000
T80.4 Rh incompatibility reaction
0.642 0.357 0.000
T80.3 ABO incompatibility reaction
0.642 0.357 0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.642 0.357 0.000
K55.8 Other vascular disorders of intestine
0.642 0.358 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.642 0.358 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.641 0.359 0.000
K75.2 Nonspecific reactive hepatitis
0.641 0.359 0.000
K75.1 Phlebitis of portal vein
0.641 0.359 0.000
N61 Inflammatory disorders of breast
0.641 0.359 0.000
I42.8 Other cardiomyopathies
0.641 0.359 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.641 0.359 0.000
I42.5 Other restrictive cardiomyopathy
0.641 0.359 0.000
I42.4 Endocardial fibroelastosis
0.641 0.359 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.641 0.359 0.000
B37.9 Candidiasis, unspecified
0.641 0.359 0.000
M94 Other disorders of cartilage
0.639 0.360 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.639 0.361 0.000
M45-M49 Spondylopathies
0.639 0.361 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.638 0.362 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
M70-M79 Other soft tissue disorders
0.637 0.363 0.000
S32 Fracture of lumbar spine and pelvis
0.636 0.364 0.000
I11 Hypertensive heart disease
0.635 0.365 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.635 0.365 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.635 0.365 0.000
Q61.2 Polycystic kidney, adult type
0.634 0.366 0.000
I22.8 Subsequent myocardial infarction of other sites
0.634 0.366 0.000
Q61.3 Polycystic kidney, unspecified
0.634 0.366 0.000
B25 Cytomegaloviral disease
0.634 0.366 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.633 0.366 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.633 0.367 0.000
K65.0 Acute peritonitis
0.633 0.367 0.000
B34 Viral infection of unspecified site
0.632 0.368 0.000
S22.9 Fracture of bony thorax, part unspecified
0.631 0.369 0.000
S22.8 Fracture of other parts of bony thorax
0.631 0.369 0.000
S22.5 Flail chest
0.631 0.369 0.000
T86 Failure and rejection of transplanted organs and tissues
0.631 0.369 0.000
C22.1 Intrahepatic bile duct carcinoma
0.631 0.369 0.000
I45.0 Right fascicular block
0.631 0.369 0.000
I51.6 Cardiovascular disease, unspecified
0.630 0.370 0.000
I51.5 Myocardial degeneration
0.630 0.370 0.000
I51.4 Myocarditis, unspecified
0.630 0.370 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.630 0.370 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.630 0.370 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.630 0.370 0.000
I51.0 Cardiac septal defect, acquired
0.630 0.370 0.000
K75.0 Abscess of liver
0.630 0.370 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.630 0.370 0.000
O21 Excessive vomiting in pregnancy
0.629 0.370 0.000
G20-G26 Extrapyramidal and movement disorders
0.629 0.370 0.000
T11 Other injuries of upper limb, level unspecified
0.628 0.371 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.628 0.372 0.000
M90 Osteopathies in diseases classified elsewhere
0.628 0.372 0.000
C18 Malignant neoplasm of colon
0.628 0.372 0.000
C22.0 Liver cell carcinoma
0.626 0.373 0.000
M43.9 Deforming dorsopathy, unspecified
0.626 0.374 0.000
M43.8 Other specified deforming dorsopathies
0.626 0.374 0.000
M43.6 Torticollis
0.626 0.374 0.000
M43.5 Other recurrent vertebral subluxation
0.626 0.374 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.626 0.374 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.626 0.374 0.000
M43.2 Other fusion of spine
0.626 0.374 0.000
M35 Other systemic involvement of connective tissue
0.626 0.374 0.000
O28 Abnormal findings on antenatal screening of mother
0.626 0.374 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.626 0.374 0.000
M93 Other osteochondropathies
0.626 0.374 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.625 0.375 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.624 0.375 0.000
M43.0 Spondylolysis
0.622 0.378 0.000
O24 Diabetes mellitus in pregnancy
0.622 0.378 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.621 0.378 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.621 0.379 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.621 0.379 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.621 0.379 0.000
A30-A49 Other bacterial diseases
0.621 0.379 0.000
T81 Complications of procedures, not elsewhere classified
0.620 0.380 0.000
K63.2 Fistula of intestine
0.620 0.380 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.619 0.381 0.000
M66 Spontaneous rupture of synovium and tendon
0.619 0.381 0.000
K55.9 Vascular disorder of intestine, unspecified
0.619 0.381 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.619 0.381 0.000
K63.8 Other specified diseases of intestine
0.619 0.381 0.000
M24.0 Loose body in joint
0.618 0.382 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.617 0.383 0.000
I45.5 Other specified heart block
0.617 0.383 0.000
I44.0 Atrioventricular block, first degree
0.616 0.384 0.000
S20.2 Contusion of thorax
0.616 0.384 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.616 0.384 0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)
0.615 0.385 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.615 0.385 0.000
K56.6 Other and unspecified intestinal obstruction
0.615 0.385 0.000
C16.8 Overlapping lesion of stomach
0.612 0.387 0.000
C16.4 Pylorus
0.612 0.387 0.000
C16.3 Pyloric antrum
0.612 0.387 0.000
C16.2 Body of stomach
0.612 0.387 0.000
C16.1 Fundus of stomach
0.612 0.387 0.000
K63.3 Ulcer of intestine
0.613 0.387 0.000
S10.9 Superficial injury of neck, part unspecified
0.612 0.387 0.000
S20.7 Multiple superficial injuries of thorax
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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