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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75522355
log Bayes Factor = 12.1753
Chromosome 16   position 6,640,457  (GRCh37) Explore rs75522355 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.991 0.009 0.000
O60-O75 Complications of labour and delivery
0.989 0.011 0.000
A00-A09 Intestinal infectious diseases
0.989 0.011 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.983 0.017 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.980 0.020 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.976 0.024 0.000
J95-J99 Other diseases of the respiratory system
0.973 0.027 0.000
A30-A49 Other bacterial diseases
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.970 0.030 0.000
J20-J22 Other acute lower respiratory infections
0.952 0.048 0.000
L03 Cellulitis
0.952 0.048 0.000
J98 Other respiratory disorders
0.944 0.056 0.000
A41 Other septicaemia
0.944 0.056 0.000
Chapter VIII Diseases of the ear and mastoid process
0.944 0.056 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.940 0.060 0.000
Chapter XX External causes of morbidity and mortality
0.931 0.069 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.931 0.069 0.000
Chapter II Neoplasms
0.930 0.070 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.922 0.078 0.000
J22 Unspecified acute lower respiratory infection
0.922 0.078 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.921 0.079 0.000
J98.1 Pulmonary collapse
0.921 0.079 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.919 0.081 0.000
A41.9 Septicaemia, unspecified
0.916 0.084 0.000
O70 Perineal laceration during delivery
0.912 0.088 0.000
Chapter V Mental and behavioural disorders
0.911 0.089 0.000
O48 Prolonged pregnancy
0.911 0.089 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.897 0.103 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.897 0.103 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.896 0.104 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.892 0.108 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.889 0.111 0.000
H80-H83 Diseases of inner ear
0.887 0.113 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.885 0.115 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.882 0.118 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.878 0.122 0.000
T81 Complications of procedures, not elsewhere classified
0.878 0.122 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.876 0.124 0.000
J90-J94 Other diseases of pleura
0.876 0.124 0.000
S10-S19 Injuries to the neck
0.866 0.134 0.000
O80-O84 Delivery
0.865 0.135 0.000
L08 Other local infections of skin and subcutaneous tissue
0.859 0.141 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.858 0.142 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
O62 Abnormalities of forces of labour
0.854 0.146 0.000
H90-H95 Other disorders of ear
0.854 0.146 0.000
S50-S59 Injuries to the elbow and forearm
0.853 0.147 0.000
J40-J47 Chronic lower respiratory diseases
0.850 0.150 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.849 0.150 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.849 0.151 0.000
O47 False labour
0.849 0.151 0.000
H81 Disorders of vestibular function
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.847 0.153 0.000
R94 Abnormal results of function studies
0.845 0.155 0.000
C34 Malignant neoplasm of bronchus and lung
0.841 0.159 0.000
L03.0 Cellulitis of finger and toe
0.838 0.162 0.000
O70.1 Second degree perineal laceration during delivery
0.836 0.164 0.000
C15-C26 Malignant neoplasms of digestive organs
0.835 0.165 0.000
O00-O08 Pregnancy with abortive outcome
0.832 0.168 0.000
D68 Other coagulation defects
0.828 0.172 0.000
S40-S49 Injuries to the shoulder and upper arm
0.827 0.173 0.000
D00-D09 In situ neoplasms
0.824 0.176 0.000
D73 Diseases of spleen
0.823 0.177 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.821 0.179 0.000
L50-L54 Urticaria and erythema
0.821 0.179 0.000
Chapter VI Diseases of the nervous system
0.816 0.184 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.815 0.185 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.815 0.185 0.000
L03.1 Cellulitis of other parts of limb
0.814 0.186 0.000
R94.5 Abnormal results of liver function studies
0.814 0.186 0.000
O40 Polyhydramnios
0.813 0.187 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.812 0.188 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.812 0.188 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.811 0.189 0.000
Chapter XXII Codes for special purposes
0.810 0.190 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.809 0.191 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.804 0.196 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.800 0.200 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.799 0.201 0.000
C16 Malignant neoplasm of stomach
0.796 0.204 0.000
S60-S69 Injuries to the wrist and hand
0.793 0.207 0.000
J43 Emphysema
0.792 0.208 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.790 0.210 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.790 0.210 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
C34.9 Bronchus or lung, unspecified
0.790 0.210 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.788 0.212 0.000
F20 Schizophrenia
0.788 0.212 0.000
H81.1 Benign paroxysmal vertigo
0.785 0.215 0.000
L03.3 Cellulitis of trunk
0.785 0.215 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.778 0.222 0.000
O63 Long labour
0.772 0.228 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.770 0.229 0.000
B15-B19 Viral hepatitis
0.770 0.230 0.000
J98.8 Other specified respiratory disorders
0.769 0.231 0.000
J98.6 Disorders of diaphragm
0.768 0.232 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.767 0.233 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.766 0.233 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.766 0.234 0.000
L03.2 Cellulitis of face
0.765 0.235 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.763 0.237 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.763 0.237 0.000
T00-T07 Injuries involving multiple body regions
0.762 0.238 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.761 0.239 0.000
S00-S09 Injuries to the head
0.761 0.239 0.000
S90-S99 Injuries to the ankle and foot
0.761 0.239 0.000
O44 Placenta praevia
0.760 0.240 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.760 0.240 0.000
T79-T79 Certain early complications of trauma
0.759 0.240 0.000
O20 Haemorrhage in early pregnancy
0.758 0.242 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.758 0.242 0.000
J92 Pleural plaque
0.757 0.243 0.000
F60-F69 Disorders of adult personality and behaviour
0.757 0.243 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.757 0.243 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.756 0.244 0.000
O85-O92 Complications predominantly related to the puerperium
0.755 0.245 0.000
A46 Erysipelas
0.754 0.245 0.000
R47-R49 Symptoms and signs involving speech and voice
0.754 0.246 0.000
H90 Conductive and sensorineural hearing loss
0.753 0.247 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.752 0.247 0.000
D73.0 Hyposplenism
0.752 0.248 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.752 0.248 0.000
O43 Placental disorders
0.752 0.248 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.752 0.248 0.000
B95-B98 Bacterial, viral and other infectious agents
0.751 0.249 0.000
D75 Other diseases of blood and blood-forming organs
0.750 0.250 0.000
O82 Single delivery by Caesarean section
0.749 0.251 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.748 0.252 0.000
S70-S79 Injuries to the hip and thigh
0.748 0.252 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.748 0.252 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.747 0.253 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.747 0.253 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.746 0.254 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.745 0.255 0.000
M45-M49 Spondylopathies
0.744 0.256 0.000
Chapter XIV Diseases of the genitourinary system
0.743 0.257 0.000
H81.0 Meniere's disease
0.742 0.258 0.000
D70 Agranulocytosis
0.740 0.260 0.000
N17-N19 Renal failure
0.739 0.261 0.000
L57.0 Actinic keratosis
0.739 0.261 0.000
D80-D89 Certain disorders involving the immune mechanism
0.738 0.262 0.000
L03.8 Cellulitis of other sites
0.736 0.264 0.000
D04 Carcinoma in situ of skin
0.734 0.266 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.734 0.266 0.000
R25 Abnormal involuntary movements
0.734 0.266 0.000
J43.9 Emphysema, unspecified
0.734 0.266 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.733 0.267 0.000
T86 Failure and rejection of transplanted organs and tissues
0.731 0.268 0.000
O66 Other obstructed labour
0.731 0.269 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.731 0.269 0.000
O62.2 Other uterine inertia
0.729 0.271 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.728 0.272 0.000
C16.9 Stomach, unspecified
0.727 0.273 0.000
D72 Other disorders of white blood cells
0.727 0.273 0.000
R29.6 Tendency to fall, not elsewhere classified
0.727 0.273 0.000
O70.0 First degree perineal laceration during delivery
0.726 0.273 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.725 0.275 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
O41 Other disorders of amniotic fluid and membranes
0.724 0.276 0.000
H91 Other hearing loss
0.721 0.279 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.721 0.279 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.721 0.279 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O34.1 Maternal care for tumour of corpus uteri
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
Q60-Q64 Congenital malformations of the urinary system
0.716 0.284 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.715 0.285 0.000
L03.9 Cellulitis, unspecified
0.714 0.286 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.714 0.286 0.000
J44 Other chronic obstructive pulmonary disease
0.714 0.286 0.000
C15 Malignant neoplasm of oesophagus
0.713 0.287 0.000
O45 Premature separation of placenta [abruptio placentae]
0.712 0.287 0.000
O33 Maternal care for known or suspected disproportion
0.712 0.287 0.000
O31 Complications specific to multiple gestation
0.712 0.287 0.000
O04 Medical abortion
0.712 0.288 0.000
S51 Open wound of forearm
0.712 0.288 0.000
O70.9 Perineal laceration during delivery, unspecified
0.711 0.289 0.000
L10-L14 Bullous disorders
0.711 0.289 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.711 0.289 0.000
O74 Complications of anaesthesia during labour and delivery
0.709 0.291 0.000
O71 Other obstetric trauma
0.709 0.291 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.709 0.291 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.709 0.291 0.000
O61 Failed induction of labour
0.709 0.291 0.000
O60 Preterm delivery
0.709 0.291 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.709 0.291 0.000
A07 Other protozoal intestinal diseases
0.709 0.291 0.000
A06 Amoebiasis
0.709 0.291 0.000
A05 Other bacterial foodborne intoxications
0.709 0.291 0.000
A03 Shigellosis
0.709 0.291 0.000
A02 Other Salmonella infections
0.709 0.291 0.000
A01 Typhoid and paratyphoid fevers
0.709 0.291 0.000
A00 Cholera
0.709 0.291 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.708 0.292 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.706 0.294 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.705 0.295 0.000
T92 Sequelae of injuries of upper limb
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
C16.0 Cardia
0.705 0.295 0.000
O47.0 False labour before 37 completed weeks of gestation
0.705 0.295 0.000
Y86 Sequelae of other accidents
0.703 0.297 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.701 0.299 0.000
N19 Unspecified renal failure
0.701 0.299 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
H83 Other diseases of inner ear
0.700 0.300 0.000
O26.9 Pregnancy-related condition, unspecified
0.700 0.300 0.000
L04 Acute lymphadenitis
0.700 0.300 0.000
L01 Impetigo
0.700 0.300 0.000
L00 Staphylococcal scalded skin syndrome
0.700 0.300 0.000
M47 Spondylosis
0.699 0.301 0.000
R19.4 Change in bowel habit
0.698 0.302 0.000
J96 Respiratory failure, not elsewhere classified
0.697 0.303 0.000
O14.9 Preeclampsia, unspecified
0.696 0.304 0.000
A48 Other bacterial diseases, not elsewhere classified
0.695 0.305 0.000
A44 Bartonellosis
0.695 0.305 0.000
A43 Nocardiosis
0.695 0.305 0.000
A42 Actinomycosis
0.695 0.305 0.000
A40 Streptococcal septicaemia
0.695 0.305 0.000
A39 Meningococcal infection
0.695 0.305 0.000
A37 Whooping cough
0.695 0.305 0.000
A36 Diphtheria
0.695 0.305 0.000
A32 Listeriosis
0.695 0.305 0.000
A31 Infection due to other mycobacteria
0.695 0.305 0.000
A30 Leprosy [Hansen's disease]
0.695 0.305 0.000
A38 Scarlet fever
0.695 0.305 0.000
A35 Other tetanus
0.695 0.305 0.000
A34 Obstetrical tetanus
0.695 0.305 0.000
A33 Tetanus neonatorum
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.695 0.305 0.000
D68.9 Coagulation defect, unspecified
0.694 0.306 0.000
T93 Sequelae of injuries of lower limb
0.694 0.306 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.694 0.306 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
F22 Persistent delusional disorders
0.691 0.309 0.000
A49 Bacterial infection of unspecified site
0.690 0.309 0.000
Q80-Q89 Other congenital malformations
0.690 0.310 0.000
T42.4 Benzodiazepines
0.690 0.310 0.000
L53 Other erythematous conditions
0.689 0.310 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.689 0.311 0.000
J94 Other pleural conditions
0.687 0.312 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
F20.0 Paranoid schizophrenia
0.686 0.314 0.000
A08 Viral and other specified intestinal infections
0.686 0.314 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.684 0.316 0.000
O30 Multiple gestation
0.683 0.316 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.683 0.317 0.000
J21 Acute bronchiolitis
0.682 0.317 0.000
J20 Acute bronchitis
0.682 0.317 0.000
N17 Acute renal failure
0.682 0.318 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.682 0.318 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.681 0.319 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.680 0.319 0.000
C34.1 Upper lobe, bronchus or lung
0.681 0.319 0.000
F20.9 Schizophrenia, unspecified
0.678 0.322 0.000
B25-B34 Other viral diseases
0.678 0.322 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.322 0.000
S80-S89 Injuries to the knee and lower leg
0.678 0.322 0.000
J98.9 Respiratory disorder, unspecified
0.677 0.323 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.677 0.323 0.000
J98.3 Compensatory emphysema
0.677 0.323 0.000
J98.2 Interstitial emphysema
0.677 0.323 0.000
A41.4 Septicaemia due to anaerobes
0.677 0.323 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.677 0.323 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.677 0.323 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.675 0.325 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.674 0.326 0.000
H92 Otalgia and effusion of ear
0.674 0.326 0.000
S52 Fracture of forearm
0.674 0.326 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.672 0.327 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.671 0.329 0.000
L20-L30 Dermatitis and eczema
0.671 0.329 0.000
D68.2 Hereditary deficiency of other clotting factors
0.670 0.330 0.000
A04 Other bacterial intestinal infections
0.670 0.330 0.000
S12 Fracture of neck
0.669 0.331 0.000
L57.4 Cutis laxa senilis
0.669 0.331 0.000
O73 Retained placenta and membranes, without haemorrhage
0.669 0.331 0.000
Q50-Q56 Congenital malformations of genital organs
0.668 0.332 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.668 0.332 0.000
O62.3 Precipitate labour
0.668 0.332 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.668 0.332 0.000
Y35-Y36 Legal intervention and operations of war
0.668 0.332 0.000
Y10-Y34 Event of undetermined intent
0.668 0.332 0.000
Y00-Y09 Assault
0.668 0.332 0.000
X85-X99 Assault
0.668 0.332 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.668 0.332 0.000
X50-X57 Overexertion, travel and privation
0.668 0.332 0.000
X30-X39 Exposure to forces of nature
0.668 0.332 0.000
X20-X29 Contact with venomous animals and plants
0.668 0.332 0.000
X10-X19 Contact with heat and hot substances
0.668 0.332 0.000
X00-X09 Exposure to smoke, fire and flames
0.668 0.332 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.668 0.332 0.000
W75-W84 Other accidental threats to breathing
0.668 0.332 0.000
W65-W74 Accidental drowning and submersion
0.668 0.332 0.000
W50-W64 Exposure to animate mechanical forces
0.668 0.332 0.000
V98-V99 Other and unspecified transport accidents
0.668 0.332 0.000
V95-V97 Air and space transport accidents
0.668 0.332 0.000
V90-V94 Water transport accidents
0.668 0.332 0.000
V70-V79 Bus occupant injured in transport accident
0.668 0.332 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.668 0.332 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.668 0.332 0.000
V40-V49 Car occupant injured in transport accident
0.668 0.332 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.668 0.332 0.000
V01-V09 Pedestrian injured in transport accident
0.668 0.332 0.000
M47.8 Other spondylosis
0.668 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
Y44 Agents primarily affecting blood constituents
0.667 0.333 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.667 0.333 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.667 0.333 0.000
J91 Pleural effusion in conditions classified elsewhere
0.666 0.334 0.000
J00-J06 Acute upper respiratory infections
0.664 0.336 0.000
A41.8 Other specified septicaemia
0.664 0.336 0.000
S13.4 Sprain and strain of cervical spine
0.664 0.336 0.000
G90-G99 Other disorders of the nervous system
0.664 0.336 0.000
R19.5 Other fecal abnormalities
0.662 0.338 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.662 0.338 0.000
N18 Chronic renal failure
0.661 0.339 0.000
R87 Abnormal findings in specimens from female genital organs
0.661 0.339 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.661 0.339 0.000
D74 Methaemoglobinaemia
0.661 0.339 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.661 0.339 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.661 0.339 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.660 0.339 0.000
O15 Eclampsia
0.660 0.340 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.660 0.340 0.000
O80 Single spontaneous delivery
0.660 0.340 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.659 0.341 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.659 0.341 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.659 0.341 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.659 0.341 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.659 0.341 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.659 0.341 0.000
O34.6 Maternal care for abnormality of vagina
0.659 0.341 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.659 0.341 0.000
O34.4 Maternal care for other abnormalities of cervix
0.659 0.341 0.000
O34.3 Maternal care for cervical incompetence
0.659 0.341 0.000
O34.0 Maternal care for congenital malformation of uterus
0.659 0.341 0.000
M20-M25 Other joint disorders
0.659 0.341 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.658 0.342 0.000
L05 Pilonidal cyst
0.657 0.343 0.000
M40-M43 Deforming dorsopathies
0.657 0.343 0.000
T66-T78 Other and unspecified effects of external causes
0.656 0.344 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.655 0.345 0.000
O82.1 Delivery by emergency Caesarean section
0.655 0.345 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.655 0.345 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
O70.3 Fourth degree perineal laceration during delivery
0.654 0.346 0.000
S00 Superficial injury of head
0.654 0.346 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.653 0.347 0.000
F70-F79 Mental retardation
0.653 0.347 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.653 0.347 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.652 0.348 0.000
O16 Unspecified maternal hypertension
0.652 0.348 0.000
F25 Schizoaffective disorders
0.651 0.349 0.000
R10 Abdominal and pelvic pain
0.651 0.349 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.650 0.350 0.000
O36 Maternal care for other known or suspected foetal problems
0.650 0.350 0.000
C21 Malignant neoplasm of anus and anal canal
0.648 0.351 0.000
D69 Purpura and other haemorrhagic conditions
0.648 0.352 0.000
D68.8 Other specified coagulation defects
0.647 0.353 0.000
O21 Excessive vomiting in pregnancy
0.647 0.353 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.647 0.353 0.000
J93 Pneumothorax
0.647 0.353 0.000
F60 Specific personality disorders
0.646 0.354 0.000
O20.0 Threatened abortion
0.646 0.354 0.000
X60-X84 Intentional self-harm
0.646 0.354 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.645 0.354 0.000
B07 Viral warts
0.645 0.355 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.644 0.355 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.644 0.356 0.000
O29 Complications of anaesthesia during pregnancy
0.643 0.357 0.000
O28 Abnormal findings on antenatal screening of mother
0.643 0.357 0.000
O23 Infections of genito-urinary tract in pregnancy
0.643 0.357 0.000
O22 Venous complications in pregnancy
0.643 0.357 0.000
O25 Malnutrition in pregnancy
0.643 0.357 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.643 0.357 0.000
N99-N99 Other disorders of the genitourinary system
0.643 0.357 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.642 0.358 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.642 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.642 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.642 0.358 0.000
Q00-Q07 Congenital malformations of the nervous system
0.642 0.358 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.642 0.358 0.000
O32.2 Maternal care for transverse and oblique lie
0.642 0.358 0.000
R10.1 Pain localised to upper abdomen
0.641 0.359 0.000
C20 Malignant neoplasm of rectum
0.641 0.359 0.000
N17.9 Acute renal failure, unspecified
0.641 0.359 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.640 0.360 0.000
C34.0 Main bronchus
0.640 0.360 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.639 0.361 0.000
R47 Speech disturbances, not elsewhere classified
0.639 0.361 0.000
O24 Diabetes mellitus in pregnancy
0.639 0.361 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.639 0.361 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.638 0.362 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.638 0.362 0.000
F29 Unspecified nonorganic psychosis
0.638 0.362 0.000
D67 Hereditary factor IX deficiency
0.637 0.363 0.000
D66 Hereditary factor VIII deficiency
0.637 0.363 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.637 0.363 0.000
J92.0 Pleural plaque with presence of asbestos
0.637 0.363 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.637 0.363 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.636 0.364 0.000
O03 Spontaneous abortion
0.635 0.365 0.000
J43.2 Centrilobular emphysema
0.635 0.365 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.634 0.365 0.000
L58 Radiodermatitis
0.634 0.365 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.634 0.365 0.000
L55 Sunburn
0.634 0.365 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.634 0.366 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.634 0.366 0.000
J42 Unspecified chronic bronchitis
0.634 0.366 0.000
F80-F89 Disorders of psychological development
0.634 0.366 0.000
L91 Hypertrophic disorders of skin
0.633 0.367 0.000
J80 Adult respiratory distress syndrome
0.633 0.367 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.633 0.367 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.633 0.367 0.000
D05 Carcinoma in situ of breast
0.633 0.367 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.632 0.368 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.632 0.368 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.632 0.368 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.632 0.368 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.632 0.368 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.632 0.368 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.632 0.368 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.632 0.368 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.632 0.368 0.000
T36 Poisoning by systemic antibiotics
0.632 0.368 0.000
D06 Carcinoma in situ of cervix uteri
0.632 0.368 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.631 0.368 0.000
R06 Abnormalities of breathing
0.630 0.370 0.000
F40 Phobic anxiety disorders
0.630 0.370 0.000
M91-M94 Chondropathies
0.630 0.370 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.630 0.370 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.630 0.370 0.000
C32 Malignant neoplasm of larynx
0.630 0.370 0.000
C31 Malignant neoplasm of accessory sinuses
0.630 0.370 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.630 0.370 0.000
C37 Malignant neoplasm of thymus
0.630 0.370 0.000
C33 Malignant neoplasm of trachea
0.630 0.370 0.000
T81.9 Unspecified complication of procedure
0.629 0.371 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.629 0.371 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.629 0.371 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.628 0.372 0.000
Y88 Sequelae of surgical and medical care as external cause
0.628 0.372 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.628 0.372 0.000
S65 Injury of blood vessels at wrist and hand level
0.628 0.372 0.000
S69 Other and unspecified injuries of wrist and hand
0.627 0.373 0.000
C01 Malignant neoplasm of base of tongue
0.627 0.373 0.000
B02 Zoster [herpes zoster]
0.626 0.374 0.000
D68.0 Von Willebrand's disease
0.626 0.374 0.000
O72 Postpartum haemorrhage
0.626 0.374 0.000
O04.9 Complete or unspecified, without complication
0.626 0.374 0.000
D04.3 Skin of other and unspecified parts of face
0.625 0.375 0.000
V10-V19 Pedal cyclist injured in transport accident
0.625 0.375 0.000
J60-J70 Lung diseases due to external agents
0.625 0.375 0.000
G57 Mononeuropathies of lower limb
0.625 0.375 0.000
C07 Malignant neoplasm of parotid gland
0.624 0.376 0.000
C34.3 Lower lobe, bronchus or lung
0.623 0.377 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.622 0.378 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.622 0.378 0.000
R27 Other lack of coordination
0.622 0.378 0.000
O32.0 Maternal care for unstable lie
0.622 0.378 0.000
S62 Fracture at wrist and hand level
0.622 0.378 0.000
T17 Foreign body in respiratory tract
0.622 0.378 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.622 0.378 0.000
S19 Other and unspecified injuries of neck
0.621 0.379 0.000
S17 Crushing injury of neck
0.621 0.379 0.000
S15 Injury of blood vessels at neck level
0.621 0.379 0.000
S14 Injury of nerves and spinal cord at neck level
0.621 0.379 0.000
S11 Open wound of neck
0.621 0.379 0.000
S10 Superficial injury of neck
0.621 0.379 0.000
S18 Traumatic amputation at neck level
0.621 0.379 0.000
S16 Injury of muscle and tendon at neck level
0.621 0.379 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.621 0.379 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.620 0.379 0.000
O84 Multiple delivery
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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