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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2229288
log Bayes Factor = 0.309738
Chromosome 16   position 72,828,304  (GRCh37) Explore rs2229288 on Ensembl!
Variant rs2229288 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.507 0.493 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.503 0.497 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.500 0.500 0.000
Chapter XIV Diseases of the genitourinary system
0.494 0.506 0.000
Chapter IX Diseases of the circulatory system
0.488 0.512 0.000
O60-O75 Complications of labour and delivery
0.485 0.515 0.000
I30-I52 Other forms of heart disease
0.479 0.521 0.000
M70-M79 Other soft tissue disorders
0.467 0.533 0.000
N20-N23 Urolithiasis
0.467 0.533 0.000
O70 Perineal laceration during delivery
0.465 0.535 0.000
M15-M19 Arthrosis
0.460 0.540 0.000
N60-N64 Disorders of breast
0.458 0.542 0.000
O70.0 First degree perineal laceration during delivery
0.448 0.552 0.000
Chapter II Neoplasms
0.445 0.555 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.441 0.559 0.000
N20 Calculus of kidney and ureter
0.435 0.565 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.435 0.565 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.432 0.568 0.000
I47 Paroxysmal tachycardia
0.426 0.574 0.000
M75 Shoulder lesions
0.422 0.578 0.000
Chapter VII Diseases of the eye and adnexa
0.421 0.579 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.418 0.582 0.000
M20-M25 Other joint disorders
0.416 0.584 0.000
C15-C26 Malignant neoplasms of digestive organs
0.414 0.586 0.000
Chapter VI Diseases of the nervous system
0.412 0.588 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.410 0.590 0.000
I84 Haemorrhoids
0.410 0.590 0.000
M45-M49 Spondylopathies
0.406 0.594 0.000
N63 Unspecified lump in breast
0.401 0.599 0.000
N40-N51 Diseases of male genital organs
0.399 0.601 0.000
M17 Gonarthrosis [arthrosis of knee]
0.397 0.603 0.000
M16 Coxarthrosis [arthrosis of hip]
0.395 0.605 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.393 0.607 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.392 0.608 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.391 0.609 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.391 0.609 0.000
I42 Cardiomyopathy
0.390 0.610 0.000
I34 Nonrheumatic mitral valve disorders
0.389 0.611 0.000
N23 Unspecified renal colic
0.388 0.612 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.388 0.612 0.000
I35 Nonrheumatic aortic valve disorders
0.388 0.612 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.388 0.612 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.387 0.613 0.000
I49 Other cardiac arrhythmias
0.386 0.614 0.000
C18 Malignant neoplasm of colon
0.382 0.618 0.000
N20.0 Calculus of kidney
0.382 0.618 0.000
N20.1 Calculus of ureter
0.382 0.618 0.000
I46 Cardiac arrest
0.375 0.625 0.000
N60 Benign mammary dysplasia
0.374 0.626 0.000
M17.9 Gonarthrosis, unspecified
0.373 0.627 0.000
S00-S09 Injuries to the head
0.370 0.630 0.000
N25-N29 Other disorders of kidney and ureter
0.369 0.631 0.000
H30-H36 Disorders of choroid and retina
0.367 0.633 0.000
M75.4 Impingement syndrome of shoulder
0.367 0.633 0.000
Chapter VIII Diseases of the ear and mastoid process
0.366 0.634 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.364 0.636 0.000
Chapter XXII Codes for special purposes
0.364 0.636 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.364 0.636 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.364 0.636 0.000
M05-M14 Inflammatory polyarthropathies
0.364 0.636 0.000
Chapter I Certain infectious and parasitic diseases
0.363 0.637 0.000
N92 Excessive, frequent and irregular menstruation
0.363 0.637 0.000
M16.1 Other primary coxarthrosis
0.363 0.637 0.000
I47.2 Ventricular tachycardia
0.363 0.637 0.000
O72 Postpartum haemorrhage
0.362 0.638 0.000
I50 Heart failure
0.361 0.639 0.000
O85-O92 Complications predominantly related to the puerperium
0.361 0.639 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.359 0.641 0.000
M91-M94 Chondropathies
0.359 0.641 0.000
M86-M90 Other osteopathies
0.359 0.641 0.000
M60-M63 Disorders of muscles
0.359 0.641 0.000
M00-M03 Infectious arthropathies
0.359 0.641 0.000
N61 Inflammatory disorders of breast
0.357 0.643 0.000
M65-M68 Disorders of synovium and tendon
0.357 0.643 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.356 0.643 0.000
N99-N99 Other disorders of the genitourinary system
0.354 0.645 0.000
O00-O08 Pregnancy with abortive outcome
0.354 0.646 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.354 0.646 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.354 0.646 0.000
D00-D09 In situ neoplasms
0.354 0.646 0.000
I47.1 Supraventricular tachycardia
0.354 0.646 0.000
N10-N16 Renal tubulo-interstitial diseases
0.352 0.648 0.000
O70.1 Second degree perineal laceration during delivery
0.352 0.648 0.000
M19 Other arthrosis
0.352 0.648 0.000
M40-M43 Deforming dorsopathies
0.351 0.648 0.000
I05-I09 Chronic rheumatic heart diseases
0.350 0.650 0.000
I00-I02 Acute rheumatic fever
0.350 0.650 0.000
M23 Internal derangement of knee
0.350 0.650 0.000
M72 Fibroblastic disorders
0.350 0.650 0.000
I31 Other diseases of pericardium
0.349 0.651 0.000
I44 Atrioventricular and left bundle-branch block
0.348 0.651 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.348 0.652 0.000
O42 Premature rupture of membranes
0.348 0.652 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.348 0.652 0.000
O74 Complications of anaesthesia during labour and delivery
0.348 0.652 0.000
O73 Retained placenta and membranes, without haemorrhage
0.348 0.652 0.000
O71 Other obstetric trauma
0.348 0.652 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.348 0.652 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.348 0.652 0.000
O66 Other obstructed labour
0.348 0.652 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.348 0.652 0.000
O62 Abnormalities of forces of labour
0.348 0.652 0.000
O61 Failed induction of labour
0.348 0.652 0.000
O60 Preterm delivery
0.348 0.652 0.000
I84.9 Unspecified haemorrhoids without complication
0.346 0.654 0.000
I45 Other conduction disorders
0.345 0.655 0.000
M75.0 Adhesive capsulitis of shoulder
0.343 0.656 0.000
I52 Other heart disorders in diseases classified elsewhere
0.343 0.656 0.000
I48 Atrial fibrillation and flutter
0.343 0.656 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.343 0.656 0.000
I41 Myocarditis in diseases classified elsewhere
0.343 0.656 0.000
I40 Acute myocarditis
0.343 0.656 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.343 0.656 0.000
I37 Pulmonary valve disorders
0.343 0.656 0.000
I36 Nonrheumatic tricuspid valve disorders
0.343 0.656 0.000
I33 Acute and subacute endocarditis
0.343 0.656 0.000
I32 Pericarditis in diseases classified elsewhere
0.343 0.656 0.000
I30 Acute pericarditis
0.343 0.656 0.000
I38 Endocarditis, valve unspecified
0.343 0.656 0.000
I84.6 Residual haemorrhoidal skin tags
0.343 0.657 0.000
N94.1 Dyspareunia
0.343 0.657 0.000
S50-S59 Injuries to the elbow and forearm
0.342 0.658 0.000
M22 Disorders of patella
0.342 0.658 0.000
N62 Hypertrophy of breast
0.340 0.660 0.000
O63 Long labour
0.338 0.661 0.000
N00-N08 Glomerular diseases
0.338 0.662 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.338 0.662 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.338 0.662 0.000
O80-O84 Delivery
0.337 0.663 0.000
C18.9 Colon, unspecified
0.337 0.663 0.000
S60-S69 Injuries to the wrist and hand
0.336 0.664 0.000
M77 Other enthesopathies
0.335 0.665 0.000
M76 Enthesopathies of lower limb, excluding foot
0.335 0.665 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.335 0.665 0.000
M71 Other bursopathies
0.335 0.665 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.335 0.665 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.335 0.665 0.000
N21 Calculus of lower urinary tract
0.335 0.665 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.335 0.665 0.000
M47 Spondylosis
0.334 0.666 0.000
O70.9 Perineal laceration during delivery, unspecified
0.333 0.666 0.000
O70.3 Fourth degree perineal laceration during delivery
0.333 0.666 0.000
O70.2 Third degree perineal laceration during delivery
0.333 0.666 0.000
C20 Malignant neoplasm of rectum
0.333 0.667 0.000
N94.6 Dysmenorrhoea, unspecified
0.331 0.669 0.000
I84.8 Unspecified haemorrhoids with other complications
0.331 0.669 0.000
M15 Polyarthrosis
0.330 0.670 0.000
I84.1 Internal haemorrhoids with other complications
0.329 0.671 0.000
H33 Retinal detachments and breaks
0.329 0.671 0.000
I35.1 Aortic (valve) insufficiency
0.329 0.671 0.000
N64 Other disorders of breast
0.328 0.672 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.327 0.673 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.327 0.673 0.000
Chapter XX External causes of morbidity and mortality
0.326 0.674 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.326 0.674 0.000
M79.6 Pain in limb
0.324 0.675 0.000
M80-M85 Disorders of bone density and structure
0.324 0.676 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.323 0.677 0.000
I73 Other peripheral vascular diseases
0.323 0.677 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.322 0.677 0.000
I60-I69 Cerebrovascular diseases
0.321 0.678 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.321 0.679 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.319 0.681 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.319 0.681 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.319 0.681 0.000
C51-C58 Malignant neoplasms of female genital organs
0.319 0.681 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.319 0.681 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.319 0.681 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.319 0.681 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.319 0.681 0.000
M50-M54 Other dorsopathies
0.318 0.681 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.318 0.682 0.000
O36 Maternal care for other known or suspected foetal problems
0.317 0.682 0.000
I51 Complications and ill-defined descriptions of heart disease
0.317 0.683 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.317 0.683 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.316 0.684 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.316 0.684 0.000
T79-T79 Certain early complications of trauma
0.316 0.684 0.000
T66-T78 Other and unspecified effects of external causes
0.316 0.684 0.000
T33-T35 Frostbite
0.316 0.684 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.316 0.684 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.316 0.684 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.316 0.684 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.316 0.684 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.316 0.684 0.000
T00-T07 Injuries involving multiple body regions
0.316 0.684 0.000
S90-S99 Injuries to the ankle and foot
0.316 0.684 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.316 0.684 0.000
S10-S19 Injuries to the neck
0.316 0.684 0.000
H43-H45 Disorders of vitreous body and globe
0.316 0.684 0.000
C18.7 Sigmoid colon
0.315 0.685 0.000
I42.9 Cardiomyopathy, unspecified
0.315 0.685 0.000
S20-S29 Injuries to the thorax
0.314 0.686 0.000
M18 Arthrosis of first carpometacarpal joint
0.314 0.686 0.000
G90-G99 Other disorders of the nervous system
0.312 0.687 0.000
S40-S49 Injuries to the shoulder and upper arm
0.312 0.687 0.000
N72 Inflammatory disease of cervix uteri
0.312 0.688 0.000
N20.9 Urinary calculus, unspecified
0.312 0.688 0.000
N20.2 Calculus of kidney with calculus of ureter
0.312 0.688 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.312 0.688 0.000
I88 Nonspecific lymphadenitis
0.312 0.688 0.000
I87 Other disorders of veins
0.312 0.688 0.000
I86 Varicose veins of other sites
0.312 0.688 0.000
I85 Oesophageal varices
0.312 0.688 0.000
I82 Other venous embolism and thrombosis
0.312 0.688 0.000
I81 Portal vein thrombosis
0.312 0.688 0.000
I34.0 Mitral (valve) insufficiency
0.312 0.688 0.000
I83 Varicose veins of lower extremities
0.312 0.688 0.000
M75.1 Rotator cuff syndrome
0.311 0.688 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.311 0.689 0.000
M23.3 Other meniscus derangements
0.311 0.689 0.000
O47 False labour
0.311 0.689 0.000
O16 Unspecified maternal hypertension
0.311 0.689 0.000
N42 Other disorders of prostate
0.311 0.689 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.311 0.689 0.000
G20-G26 Extrapyramidal and movement disorders
0.310 0.690 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.310 0.690 0.000
O45 Premature separation of placenta [abruptio placentae]
0.310 0.690 0.000
O44 Placenta praevia
0.310 0.690 0.000
O43 Placental disorders
0.310 0.690 0.000
O41 Other disorders of amniotic fluid and membranes
0.310 0.690 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.310 0.690 0.000
O33 Maternal care for known or suspected disproportion
0.310 0.690 0.000
O31 Complications specific to multiple gestation
0.310 0.690 0.000
O30 Multiple gestation
0.310 0.690 0.000
O40 Polyhydramnios
0.310 0.690 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.310 0.690 0.000
G40-G47 Episodic and paroxysmal disorders
0.309 0.691 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.309 0.691 0.000
O48 Prolonged pregnancy
0.308 0.691 0.000
H53-H54 Visual disturbances and blindness
0.308 0.692 0.000
N89 Other noninflammatory disorders of vagina
0.308 0.692 0.000
O20 Haemorrhage in early pregnancy
0.308 0.692 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.305 0.694 0.000
I47.0 Reentry ventricular arrhythmia
0.305 0.694 0.000
I84.5 External haemorrhoids without complication
0.305 0.695 0.000
M75.5 Bursitis of shoulder
0.304 0.696 0.000
M24 Other specific joint derangements
0.304 0.696 0.000
I49.8 Other specified cardiac arrhythmias
0.304 0.696 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.304 0.696 0.000
M25 Other joint disorders, not elsewhere classified
0.304 0.696 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.303 0.697 0.000
M35 Other systemic involvement of connective tissue
0.302 0.697 0.000
M75.8 Other shoulder lesions
0.302 0.697 0.000
M75.9 Shoulder lesion, unspecified
0.302 0.697 0.000
M75.3 Calcific tendinitis of shoulder
0.302 0.697 0.000
M75.2 Bicipital tendinitis
0.302 0.697 0.000
H55-H59 Other disorders of eye and adnexa
0.302 0.698 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.302 0.698 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.302 0.698 0.000
H10-H13 Disorders of conjunctiva
0.302 0.698 0.000
Chapter V Mental and behavioural disorders
0.302 0.698 0.000
I46.0 Cardiac arrest with successful resuscitation
0.301 0.699 0.000
M79.8 Other specified soft tissue disorders
0.301 0.699 0.000
C64-C68 Malignant neoplasms of urinary tract
0.300 0.700 0.000
Chapter XI Diseases of the digestive system
0.300 0.700 0.000
S80-S89 Injuries to the knee and lower leg
0.300 0.700 0.000
N98 Complications associated with artificial fertilisation
0.300 0.700 0.000
N97 Female infertility
0.300 0.700 0.000
N91 Absent, scanty and rare menstruation
0.300 0.700 0.000
N87 Dysplasia of cervix uteri
0.300 0.700 0.000
N82 Fistulae involving female genital tract
0.300 0.700 0.000
N96 Habitual aborter
0.300 0.700 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.298 0.701 0.000
M34 Systemic sclerosis
0.298 0.701 0.000
M33 Dermatopolymyositis
0.298 0.701 0.000
M32 Systemic lupus erythematosus
0.298 0.701 0.000
M31 Other necrotising vasculopathies
0.298 0.701 0.000
M30 Polyarteritis nodosa and related conditions
0.298 0.701 0.000
M21 Other acquired deformities of limbs
0.298 0.701 0.000
N86 Erosion and ectropion of cervix uteri
0.298 0.701 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.298 0.702 0.000
I34.1 Mitral (valve) prolapse
0.298 0.702 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.298 0.702 0.000
N40 Hyperplasia of prostate
0.298 0.702 0.000
I49.9 Cardiac arrhythmia, unspecified
0.297 0.702 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.297 0.703 0.000
C25 Malignant neoplasm of pancreas
0.297 0.703 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.297 0.703 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.297 0.703 0.000
C21 Malignant neoplasm of anus and anal canal
0.297 0.703 0.000
C17 Malignant neoplasm of small intestine
0.297 0.703 0.000
C16 Malignant neoplasm of stomach
0.297 0.703 0.000
C15 Malignant neoplasm of oesophagus
0.297 0.703 0.000
C23 Malignant neoplasm of gallbladder
0.297 0.703 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.297 0.703 0.000
M48 Other spondylopathies
0.296 0.703 0.000
S70-S79 Injuries to the hip and thigh
0.296 0.704 0.000
Chapter X Diseases of the respiratory system
0.296 0.704 0.000
I42.0 Dilated cardiomyopathy
0.296 0.704 0.000
N80 Endometriosis
0.295 0.704 0.000
G70-G73 Diseases of myoneural junction and muscle
0.295 0.705 0.000
G30-G32 Other degenerative diseases of the nervous system
0.295 0.705 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.295 0.705 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.295 0.705 0.000
N60.8 Other benign mammary dysplasias
0.295 0.705 0.000
C18.2 Ascending colon
0.295 0.705 0.000
N75 Diseases of Bartholin's gland
0.294 0.705 0.000
O29 Complications of anaesthesia during pregnancy
0.294 0.706 0.000
O28 Abnormal findings on antenatal screening of mother
0.294 0.706 0.000
O24 Diabetes mellitus in pregnancy
0.294 0.706 0.000
O23 Infections of genito-urinary tract in pregnancy
0.294 0.706 0.000
O22 Venous complications in pregnancy
0.294 0.706 0.000
O21 Excessive vomiting in pregnancy
0.294 0.706 0.000
O25 Malnutrition in pregnancy
0.294 0.706 0.000
N60.1 Diffuse cystic mastopathy
0.294 0.706 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.294 0.706 0.000
I84.4 External haemorrhoids with other complications
0.294 0.706 0.000
I84.3 External thrombosed haemorrhoids
0.294 0.706 0.000
I84.0 Internal thrombosed haemorrhoids
0.294 0.706 0.000
I50.0 Congestive heart failure
0.294 0.706 0.000
S00 Superficial injury of head
0.293 0.707 0.000
H25-H28 Disorders of lens
0.293 0.707 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.292 0.708 0.000
I77 Other disorders of arteries and arterioles
0.292 0.708 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.292 0.708 0.000
D45 Polycythaemia vera
0.292 0.708 0.000
M49 Spondylopathies in diseases classified elsewhere
0.291 0.709 0.000
M46 Other inflammatory spondylopathies
0.291 0.709 0.000
M45 Ankylosing spondylitis
0.291 0.709 0.000
I44.1 Atrioventricular block, second degree
0.290 0.709 0.000
N48 Other disorders of penis
0.290 0.710 0.000
N43 Hydrocele and spermatocele
0.289 0.711 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.288 0.711 0.000
D05 Carcinoma in situ of breast
0.288 0.712 0.000
B95-B98 Bacterial, viral and other infectious agents
0.288 0.712 0.000
O32.1 Maternal care for breech presentation
0.288 0.712 0.000
N88 Other noninflammatory disorders of cervix uteri
0.288 0.712 0.000
M22.4 Chondromalacia patellae
0.288 0.712 0.000
O42.9 Premature rupture of membranes, unspecified
0.288 0.712 0.000
H34 Retinal vascular occlusions
0.287 0.712 0.000
N45 Orchitis and epididymitis
0.287 0.712 0.000
I20-I25 Ischaemic heart diseases
0.287 0.713 0.000
I50.9 Heart failure, unspecified
0.286 0.714 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.286 0.714 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.286 0.714 0.000
N41 Inflammatory diseases of prostate
0.286 0.714 0.000
N46 Male infertility
0.286 0.714 0.000
N44 Torsion of testis
0.286 0.714 0.000
S06 Intracranial injury
0.285 0.714 0.000
M17.5 Other secondary gonarthrosis
0.285 0.715 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.285 0.715 0.000
M17.3 Other posttraumatic gonarthrosis
0.285 0.715 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.285 0.715 0.000
I78 Diseases of capillaries
0.283 0.717 0.000
M16.7 Other secondary coxarthrosis
0.283 0.717 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.283 0.717 0.000
M16.5 Other posttraumatic coxarthrosis
0.283 0.717 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.283 0.717 0.000
M16.3 Other dysplastic coxarthrosis
0.283 0.717 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.283 0.717 0.000
M16.0 Primary coxarthrosis, bilateral
0.283 0.717 0.000
S01 Open wound of head
0.282 0.718 0.000
M13 Other arthritis
0.282 0.718 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.282 0.718 0.000
I74 Arterial embolism and thrombosis
0.282 0.718 0.000
I72 Other aneurysm
0.282 0.718 0.000
I70 Atherosclerosis
0.282 0.718 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.282 0.718 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.281 0.719 0.000
N94.5 Secondary dysmenorrhoea
0.281 0.719 0.000
N94.4 Primary dysmenorrhoea
0.281 0.719 0.000
N94.3 Premenstrual tension syndrome
0.281 0.719 0.000
N94.2 Vaginismus
0.281 0.719 0.000
N94.0 Mittelschmerz
0.281 0.719 0.000
O26.8 Other specified pregnancy-related conditions
0.281 0.719 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.281 0.719 0.000
O15 Eclampsia
0.280 0.719 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.280 0.719 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.280 0.719 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.280 0.719 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.280 0.719 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.280 0.719 0.000
M79.9 Soft tissue disorder, unspecified
0.280 0.720 0.000
M79.7 Fibromyalgia
0.280 0.720 0.000
M79.5 Residual foreign body in soft tissue
0.280 0.720 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.280 0.720 0.000
M79.3 Panniculitis, unspecified
0.280 0.720 0.000
M79.2 Neuralgia and neuritis, unspecified
0.280 0.720 0.000
M79.1 Myalgia
0.280 0.720 0.000
H33.0 Retinal detachment with retinal break
0.280 0.720 0.000
I42.8 Other cardiomyopathies
0.280 0.720 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.280 0.720 0.000
I42.6 Alcoholic cardiomyopathy
0.280 0.720 0.000
I42.5 Other restrictive cardiomyopathy
0.280 0.720 0.000
I42.4 Endocardial fibroelastosis
0.280 0.720 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.280 0.720 0.000
I42.2 Other hypertrophic cardiomyopathy
0.280 0.720 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.280 0.720 0.000
H40-H42 Glaucoma
0.279 0.721 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.279 0.721 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.279 0.721 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.279 0.721 0.000
M79.0 Rheumatism, unspecified
0.279 0.721 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.279 0.721 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.278 0.722 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.278 0.722 0.000
N76 Other inflammation of vagina and vulva
0.278 0.722 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.278 0.722 0.000
N71 Inflammatory disease of uterus, except cervix
0.278 0.722 0.000
N70 Salpingitis and oophoritis
0.278 0.722 0.000
I35.9 Aortic valve disorder, unspecified
0.278 0.722 0.000
I35.8 Other aortic valve disorders
0.278 0.722 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.278 0.722 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.278 0.722 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.278 0.722 0.000
O64.5 Obstructed labour due to compound presentation
0.278 0.722 0.000
O64.4 Obstructed labour due to shoulder presentation
0.278 0.722 0.000
O64.3 Obstructed labour due to brow presentation
0.278 0.722 0.000
O64.2 Obstructed labour due to face presentation
0.278 0.722 0.000
O64.1 Obstructed labour due to breech presentation
0.278 0.722 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.277 0.722 0.000
O97 Death from sequelae of direct obstetric causes
0.277 0.722 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.277 0.722 0.000
O95 Obstetric death of unspecified cause
0.277 0.722 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.277 0.722 0.000
N85.0 Endometrial glandular hyperplasia
0.277 0.722 0.000
C50-C50 Malignant neoplasm of breast
0.277 0.723 0.000
I49.5 Sick sinus syndrome
0.277 0.723 0.000
I49.4 Other and unspecified premature depolarisation
0.277 0.723 0.000
I49.3 Ventricular premature depolarisation
0.277 0.723 0.000
I49.2 Junctional premature depolarisation
0.277 0.723 0.000
I49.1 Atrial premature depolarisation
0.277 0.723 0.000
I49.0 Ventricular fibrillation and flutter
0.277 0.723 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.276 0.724 0.000
I73.0 Raynaud's syndrome
0.276 0.724 0.000
C18.8 Overlapping lesion of colon
0.274 0.726 0.000
C18.6 Descending colon
0.274 0.726 0.000
C18.5 Splenic flexure
0.274 0.726 0.000
C18.4 Transverse colon
0.274 0.726 0.000
C18.3 Hepatic flexure
0.274 0.726 0.000
C18.1 Appendix
0.274 0.726 0.000
C18.0 Caecum
0.274 0.726 0.000
M19.9 Arthrosis, unspecified
0.274 0.726 0.000
O72.1 Other immediate postpartum haemorrhage
0.274 0.726 0.000
H35 Other retinal disorders
0.273 0.727 0.000
I84.2 Internal haemorrhoids without complication
0.273 0.727 0.000
H80-H83 Diseases of inner ear
0.272 0.728 0.000
I71 Aortic aneurysm and dissection
0.271 0.728 0.000
S52 Fracture of forearm
0.271 0.729 0.000
I44.2 Atrioventricular block, complete
0.271 0.729 0.000
H65-H75 Diseases of middle ear and mastoid
0.271 0.729 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.270 0.730 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.270 0.730 0.000
S09 Other and unspecified injuries of head
0.269 0.731 0.000
I46.9 Cardiac arrest, unspecified
0.269 0.731 0.000
I46.1 Sudden cardiac death, so described
0.269 0.731 0.000
N60.9 Benign mammary dysplasia, unspecified
0.268 0.732 0.000
N60.4 Mammary duct ectasia
0.268 0.732 0.000
N60.3 Fibrosclerosis of breast
0.268 0.732 0.000
N60.2 Fibroadenosis of breast
0.268 0.732 0.000
N60.0 Solitary cyst of breast
0.268 0.732 0.000
O03 Spontaneous abortion
0.268 0.732 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.267 0.732 0.000
I35.0 Aortic (valve) stenosis
0.266 0.734 0.000
G35 Multiple sclerosis
0.266 0.734 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.266 0.734 0.000
K55-K64 Other diseases of intestines
0.266 0.734 0.000
B35-B49 Mycoses
0.266 0.734 0.000
M47.8 Other spondylosis
0.266 0.734 0.000
C77.3 Axillary and upper limb lymph nodes
0.266 0.734 0.000
N50 Other disorders of male genital organs
0.266 0.734 0.000
S08 Traumatic amputation of part of head
0.266 0.734 0.000
S07 Crushing injury of head
0.266 0.734 0.000
S05 Injury of eye and orbit
0.266 0.734 0.000
S04 Injury of cranial nerves
0.266 0.734 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.266 0.734 0.000
S02 Fracture of skull and facial bones
0.266 0.734 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.265 0.735 0.000
H33.2 Serous retinal detachment
0.265 0.735 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.264 0.735 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.264 0.735 0.000
N27 Small kidney of unknown cause
0.264 0.735 0.000
N25 Disorders resulting from impaired renal tubular function
0.264 0.735 0.000
N26 Unspecified contracted kidney
0.264 0.735 0.000
A30-A49 Other bacterial diseases
0.264 0.736 0.000
M47.9 Spondylosis, unspecified
0.264 0.736 0.000
M79.67 Pain in limb (Ankle and foot)
0.264 0.736 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.263 0.737 0.000
H31 Other disorders of choroid
0.263 0.737 0.000
H30 Chorioretinal inflammation
0.263 0.737 0.000
H60-H62 Diseases of external ear
0.263 0.737 0.000
N85.2 Hypertrophy of uterus
0.262 0.738 0.000
G40 Epilepsy
0.261 0.738 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.261 0.739 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.261 0.739 0.000
D46 Myelodysplastic syndromes
0.261 0.739 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.261 0.739 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.261 0.739 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.261 0.739 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.261 0.739 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.261 0.739 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.261 0.739 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.261 0.739 0.000
P90-P96 Other disorders originating in the perinatal period
0.261 0.739 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.261 0.739 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.261 0.739 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.261 0.739 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.261 0.739 0.000
P35-P39 Infections specific to the perinatal period
0.261 0.739 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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