TreeWAS – Variant ID: rs2229288

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.507	0.493
Chapter XV Pregnancy, childbirth and the puerperium	0.503	0.497
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.500	0.500
Chapter XIV Diseases of the genitourinary system	0.494	0.506
Chapter IX Diseases of the circulatory system	0.488	0.512
O60-O75 Complications of labour and delivery	0.485	0.515
I30-I52 Other forms of heart disease	0.479	0.521
M70-M79 Other soft tissue disorders	0.467	0.533
N20-N23 Urolithiasis	0.467	0.533
O70 Perineal laceration during delivery	0.465	0.535
M15-M19 Arthrosis	0.460	0.540
N60-N64 Disorders of breast	0.458	0.542
O70.0 First degree perineal laceration during delivery	0.448	0.552
Chapter II Neoplasms	0.445	0.555
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.441	0.559
N20 Calculus of kidney and ureter	0.435	0.565
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.435	0.565
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.432	0.568
I47 Paroxysmal tachycardia	0.426	0.574
M75 Shoulder lesions	0.422	0.578
Chapter VII Diseases of the eye and adnexa	0.421	0.579
N80-N98 Noninflammatory disorders of female genital tract	0.418	0.582
M20-M25 Other joint disorders	0.416	0.584
C15-C26 Malignant neoplasms of digestive organs	0.414	0.586
Chapter VI Diseases of the nervous system	0.412	0.588
O20-O29 Other maternal disorders predominantly related to pregnancy	0.410	0.590
I84 Haemorrhoids	0.410	0.590
M45-M49 Spondylopathies	0.406	0.594
N63 Unspecified lump in breast	0.401	0.599
N40-N51 Diseases of male genital organs	0.399	0.601
M17 Gonarthrosis [arthrosis of knee]	0.397	0.603
M16 Coxarthrosis [arthrosis of hip]	0.395	0.605
I70-I79 Diseases of arteries, arterioles and capillaries	0.393	0.607
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.392	0.608
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.391	0.609
M79 Other soft tissue disorders, not elsewhere classified	0.391	0.609
I42 Cardiomyopathy	0.390	0.610
I34 Nonrheumatic mitral valve disorders	0.389	0.611
N23 Unspecified renal colic	0.388	0.612
N70-N77 Inflammatory diseases of female pelvic organs	0.388	0.612
I35 Nonrheumatic aortic valve disorders	0.388	0.612
O64 Obstructed labour due to malposition and malpresentation of foetus	0.388	0.612
O94-O99 Other obstetric conditions, not elsewhere classified	0.387	0.613
I49 Other cardiac arrhythmias	0.386	0.614
C18 Malignant neoplasm of colon	0.382	0.618
N20.0 Calculus of kidney	0.382	0.618
N20.1 Calculus of ureter	0.382	0.618
I46 Cardiac arrest	0.375	0.625
N60 Benign mammary dysplasia	0.374	0.626
M17.9 Gonarthrosis, unspecified	0.373	0.627
S00-S09 Injuries to the head	0.370	0.630
N25-N29 Other disorders of kidney and ureter	0.369	0.631
H30-H36 Disorders of choroid and retina	0.367	0.633
M75.4 Impingement syndrome of shoulder	0.367	0.633
Chapter VIII Diseases of the ear and mastoid process	0.366	0.634
D37-D48 Neoplasms of uncertain or unknown behaviour	0.364	0.636
Chapter XXII Codes for special purposes	0.364	0.636
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.364	0.636
Chapter XVI Certain conditions originating in the perinatal period	0.364	0.636
M05-M14 Inflammatory polyarthropathies	0.364	0.636
Chapter I Certain infectious and parasitic diseases	0.363	0.637
N92 Excessive, frequent and irregular menstruation	0.363	0.637
M16.1 Other primary coxarthrosis	0.363	0.637
I47.2 Ventricular tachycardia	0.363	0.637
O72 Postpartum haemorrhage	0.362	0.638
I50 Heart failure	0.361	0.639
O85-O92 Complications predominantly related to the puerperium	0.361	0.639
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.359	0.641
M91-M94 Chondropathies	0.359	0.641
M86-M90 Other osteopathies	0.359	0.641
M60-M63 Disorders of muscles	0.359	0.641
M00-M03 Infectious arthropathies	0.359	0.641
N61 Inflammatory disorders of breast	0.357	0.643
M65-M68 Disorders of synovium and tendon	0.357	0.643
O68 Labour and delivery complicated by foetal stress [distress]	0.356	0.643
N99-N99 Other disorders of the genitourinary system	0.354	0.645
O00-O08 Pregnancy with abortive outcome	0.354	0.646
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.354	0.646
N85 Other noninflammatory disorders of uterus, except cervix	0.354	0.646
D00-D09 In situ neoplasms	0.354	0.646
I47.1 Supraventricular tachycardia	0.354	0.646
N10-N16 Renal tubulo-interstitial diseases	0.352	0.648
O70.1 Second degree perineal laceration during delivery	0.352	0.648
M19 Other arthrosis	0.352	0.648
M40-M43 Deforming dorsopathies	0.351	0.648
I05-I09 Chronic rheumatic heart diseases	0.350	0.650
I00-I02 Acute rheumatic fever	0.350	0.650
M23 Internal derangement of knee	0.350	0.650
M72 Fibroblastic disorders	0.350	0.650
I31 Other diseases of pericardium	0.349	0.651
I44 Atrioventricular and left bundle-branch block	0.348	0.651
O32 Maternal care for known or suspected malpresentation of foetus	0.348	0.652
O42 Premature rupture of membranes	0.348	0.652
O75 Other complications of labour and delivery, not elsewhere classified	0.348	0.652
O74 Complications of anaesthesia during labour and delivery	0.348	0.652
O73 Retained placenta and membranes, without haemorrhage	0.348	0.652
O71 Other obstetric trauma	0.348	0.652
O69 Labour and delivery complicated by umbilical cord complications	0.348	0.652
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.348	0.652
O66 Other obstructed labour	0.348	0.652
O65 Obstructed labour due to maternal pelvic abnormality	0.348	0.652
O62 Abnormalities of forces of labour	0.348	0.652
O61 Failed induction of labour	0.348	0.652
O60 Preterm delivery	0.348	0.652
I84.9 Unspecified haemorrhoids without complication	0.346	0.654
I45 Other conduction disorders	0.345	0.655
M75.0 Adhesive capsulitis of shoulder	0.343	0.656
I52 Other heart disorders in diseases classified elsewhere	0.343	0.656
I48 Atrial fibrillation and flutter	0.343	0.656
I43 Cardiomyopathy in diseases classified elsewhere	0.343	0.656
I41 Myocarditis in diseases classified elsewhere	0.343	0.656
I40 Acute myocarditis	0.343	0.656
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.343	0.656
I37 Pulmonary valve disorders	0.343	0.656
I36 Nonrheumatic tricuspid valve disorders	0.343	0.656
I33 Acute and subacute endocarditis	0.343	0.656
I32 Pericarditis in diseases classified elsewhere	0.343	0.656
I30 Acute pericarditis	0.343	0.656
I38 Endocarditis, valve unspecified	0.343	0.656
I84.6 Residual haemorrhoidal skin tags	0.343	0.657
N94.1 Dyspareunia	0.343	0.657
S50-S59 Injuries to the elbow and forearm	0.342	0.658
M22 Disorders of patella	0.342	0.658
N62 Hypertrophy of breast	0.340	0.660
O63 Long labour	0.338	0.661
N00-N08 Glomerular diseases	0.338	0.662
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.338	0.662
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.338	0.662
O80-O84 Delivery	0.337	0.663
C18.9 Colon, unspecified	0.337	0.663
S60-S69 Injuries to the wrist and hand	0.336	0.664
M77 Other enthesopathies	0.335	0.665
M76 Enthesopathies of lower limb, excluding foot	0.335	0.665
M73 Soft tissue disorders in diseases classified elsewhere	0.335	0.665
M71 Other bursopathies	0.335	0.665
M70 Soft tissue disorders related to use, overuse and pressure	0.335	0.665
N22 Calculus of urinary tract in diseases classified elsewhere	0.335	0.665
N21 Calculus of lower urinary tract	0.335	0.665
O26 Maternal care for other conditions predominantly related to pregnancy	0.335	0.665
M47 Spondylosis	0.334	0.666
O70.9 Perineal laceration during delivery, unspecified	0.333	0.666
O70.3 Fourth degree perineal laceration during delivery	0.333	0.666
O70.2 Third degree perineal laceration during delivery	0.333	0.666
C20 Malignant neoplasm of rectum	0.333	0.667
N94.6 Dysmenorrhoea, unspecified	0.331	0.669
I84.8 Unspecified haemorrhoids with other complications	0.331	0.669
M15 Polyarthrosis	0.330	0.670
I84.1 Internal haemorrhoids with other complications	0.329	0.671
H33 Retinal detachments and breaks	0.329	0.671
I35.1 Aortic (valve) insufficiency	0.329	0.671
N64 Other disorders of breast	0.328	0.672
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.327	0.673
G35-G37 Demyelinating diseases of the central nervous system	0.327	0.673
Chapter XX External causes of morbidity and mortality	0.326	0.674
O46 Antepartum haemorrhage, not elsewhere classified	0.326	0.674
M79.6 Pain in limb	0.324	0.675
M80-M85 Disorders of bone density and structure	0.324	0.676
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.323	0.677
I73 Other peripheral vascular diseases	0.323	0.677
I95-I99 Other and unspecified disorders of the circulatory system	0.322	0.677
I60-I69 Cerebrovascular diseases	0.321	0.678
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.321	0.679
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.319	0.681
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.319	0.681
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.319	0.681
C51-C58 Malignant neoplasms of female genital organs	0.319	0.681
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.319	0.681
C40-C41 Malignant neoplasms of bone and articular cartilage	0.319	0.681
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.319	0.681
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.319	0.681
M50-M54 Other dorsopathies	0.318	0.681
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.318	0.682
O36 Maternal care for other known or suspected foetal problems	0.317	0.682
I51 Complications and ill-defined descriptions of heart disease	0.317	0.683
N90 Other noninflammatory disorders of vulva and perineum	0.317	0.683
T36-T50 Poisoning by drugs, medicaments and biological substances	0.316	0.684
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.316	0.684
T79-T79 Certain early complications of trauma	0.316	0.684
T66-T78 Other and unspecified effects of external causes	0.316	0.684
T33-T35 Frostbite	0.316	0.684
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.316	0.684
T26-T28 Burns and corrosions confined to eye and internal organs	0.316	0.684
T20-T25 Burns and corrosions of external body surface, specified by site	0.316	0.684
T15-T19 Effects of foreign body entering through natural orifice	0.316	0.684
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.316	0.684
T00-T07 Injuries involving multiple body regions	0.316	0.684
S90-S99 Injuries to the ankle and foot	0.316	0.684
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.316	0.684
S10-S19 Injuries to the neck	0.316	0.684
H43-H45 Disorders of vitreous body and globe	0.316	0.684
C18.7 Sigmoid colon	0.315	0.685
I42.9 Cardiomyopathy, unspecified	0.315	0.685
S20-S29 Injuries to the thorax	0.314	0.686
M18 Arthrosis of first carpometacarpal joint	0.314	0.686
G90-G99 Other disorders of the nervous system	0.312	0.687
S40-S49 Injuries to the shoulder and upper arm	0.312	0.687
N72 Inflammatory disease of cervix uteri	0.312	0.688
N20.9 Urinary calculus, unspecified	0.312	0.688
N20.2 Calculus of kidney with calculus of ureter	0.312	0.688
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.312	0.688
I88 Nonspecific lymphadenitis	0.312	0.688
I87 Other disorders of veins	0.312	0.688
I86 Varicose veins of other sites	0.312	0.688
I85 Oesophageal varices	0.312	0.688
I82 Other venous embolism and thrombosis	0.312	0.688
I81 Portal vein thrombosis	0.312	0.688
I34.0 Mitral (valve) insufficiency	0.312	0.688
I83 Varicose veins of lower extremities	0.312	0.688
M75.1 Rotator cuff syndrome	0.311	0.688
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.311	0.689
M23.3 Other meniscus derangements	0.311	0.689
O47 False labour	0.311	0.689
O16 Unspecified maternal hypertension	0.311	0.689
N42 Other disorders of prostate	0.311	0.689
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.311	0.689
G20-G26 Extrapyramidal and movement disorders	0.310	0.690
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.310	0.690
O45 Premature separation of placenta [abruptio placentae]	0.310	0.690
O44 Placenta praevia	0.310	0.690
O43 Placental disorders	0.310	0.690
O41 Other disorders of amniotic fluid and membranes	0.310	0.690
O35 Maternal care for known or suspected foetal abnormality and damage	0.310	0.690
O33 Maternal care for known or suspected disproportion	0.310	0.690
O31 Complications specific to multiple gestation	0.310	0.690
O30 Multiple gestation	0.310	0.690
O40 Polyhydramnios	0.310	0.690
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.310	0.690
G40-G47 Episodic and paroxysmal disorders	0.309	0.691
N47 Redundant prepuce, phimosis and paraphimosis	0.309	0.691
O48 Prolonged pregnancy	0.308	0.691
H53-H54 Visual disturbances and blindness	0.308	0.692
N89 Other noninflammatory disorders of vagina	0.308	0.692
O20 Haemorrhage in early pregnancy	0.308	0.692
I47.9 Paroxysmal tachycardia, unspecified	0.305	0.694
I47.0 Reentry ventricular arrhythmia	0.305	0.694
I84.5 External haemorrhoids without complication	0.305	0.695
M75.5 Bursitis of shoulder	0.304	0.696
M24 Other specific joint derangements	0.304	0.696
I49.8 Other specified cardiac arrhythmias	0.304	0.696
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.304	0.696
M25 Other joint disorders, not elsewhere classified	0.304	0.696
N92.1 Excessive and frequent menstruation with irregular cycle	0.303	0.697
M35 Other systemic involvement of connective tissue	0.302	0.697
M75.8 Other shoulder lesions	0.302	0.697
M75.9 Shoulder lesion, unspecified	0.302	0.697
M75.3 Calcific tendinitis of shoulder	0.302	0.697
M75.2 Bicipital tendinitis	0.302	0.697
H55-H59 Other disorders of eye and adnexa	0.302	0.698
H46-H48 Disorders of optic nerve and visual pathways	0.302	0.698
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.302	0.698
H10-H13 Disorders of conjunctiva	0.302	0.698
Chapter V Mental and behavioural disorders	0.302	0.698
I46.0 Cardiac arrest with successful resuscitation	0.301	0.699
M79.8 Other specified soft tissue disorders	0.301	0.699
C64-C68 Malignant neoplasms of urinary tract	0.300	0.700
Chapter XI Diseases of the digestive system	0.300	0.700
S80-S89 Injuries to the knee and lower leg	0.300	0.700
N98 Complications associated with artificial fertilisation	0.300	0.700
N97 Female infertility	0.300	0.700
N91 Absent, scanty and rare menstruation	0.300	0.700
N87 Dysplasia of cervix uteri	0.300	0.700
N82 Fistulae involving female genital tract	0.300	0.700
N96 Habitual aborter	0.300	0.700
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.298	0.701
M34 Systemic sclerosis	0.298	0.701
M33 Dermatopolymyositis	0.298	0.701
M32 Systemic lupus erythematosus	0.298	0.701
M31 Other necrotising vasculopathies	0.298	0.701
M30 Polyarteritis nodosa and related conditions	0.298	0.701
M21 Other acquired deformities of limbs	0.298	0.701
N86 Erosion and ectropion of cervix uteri	0.298	0.701
O34 Maternal care for known or suspected abnormality of pelvic organs	0.298	0.702
I34.1 Mitral (valve) prolapse	0.298	0.702
N92.0 Excessive and frequent menstruation with regular cycle	0.298	0.702
N40 Hyperplasia of prostate	0.298	0.702
I49.9 Cardiac arrhythmia, unspecified	0.297	0.702
C26 Malignant neoplasm of other and ill-defined digestive organs	0.297	0.703
C25 Malignant neoplasm of pancreas	0.297	0.703
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.297	0.703
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.297	0.703
C21 Malignant neoplasm of anus and anal canal	0.297	0.703
C17 Malignant neoplasm of small intestine	0.297	0.703
C16 Malignant neoplasm of stomach	0.297	0.703
C15 Malignant neoplasm of oesophagus	0.297	0.703
C23 Malignant neoplasm of gallbladder	0.297	0.703
C19 Malignant neoplasm of rectosigmoid junction	0.297	0.703
M48 Other spondylopathies	0.296	0.703
S70-S79 Injuries to the hip and thigh	0.296	0.704
Chapter X Diseases of the respiratory system	0.296	0.704
I42.0 Dilated cardiomyopathy	0.296	0.704
N80 Endometriosis	0.295	0.704
G70-G73 Diseases of myoneural junction and muscle	0.295	0.705
G30-G32 Other degenerative diseases of the nervous system	0.295	0.705
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.295	0.705
G00-G09 Inflammatory diseases of the central nervous system	0.295	0.705
N60.8 Other benign mammary dysplasias	0.295	0.705
C18.2 Ascending colon	0.295	0.705
N75 Diseases of Bartholin's gland	0.294	0.705
O29 Complications of anaesthesia during pregnancy	0.294	0.706
O28 Abnormal findings on antenatal screening of mother	0.294	0.706
O24 Diabetes mellitus in pregnancy	0.294	0.706
O23 Infections of genito-urinary tract in pregnancy	0.294	0.706
O22 Venous complications in pregnancy	0.294	0.706
O21 Excessive vomiting in pregnancy	0.294	0.706
O25 Malnutrition in pregnancy	0.294	0.706
N60.1 Diffuse cystic mastopathy	0.294	0.706
I84.7 Unspecified thrombosed haemorrhoids	0.294	0.706
I84.4 External haemorrhoids with other complications	0.294	0.706
I84.3 External thrombosed haemorrhoids	0.294	0.706
I84.0 Internal thrombosed haemorrhoids	0.294	0.706
I50.0 Congestive heart failure	0.294	0.706
S00 Superficial injury of head	0.293	0.707
H25-H28 Disorders of lens	0.293	0.707
C43-C44 Melanoma and other malignant neoplasms of skin	0.292	0.708
I77 Other disorders of arteries and arterioles	0.292	0.708
N85.8 Other specified noninflammatory disorders of uterus	0.292	0.708
D45 Polycythaemia vera	0.292	0.708
M49 Spondylopathies in diseases classified elsewhere	0.291	0.709
M46 Other inflammatory spondylopathies	0.291	0.709
M45 Ankylosing spondylitis	0.291	0.709
I44.1 Atrioventricular block, second degree	0.290	0.709
N48 Other disorders of penis	0.290	0.710
N43 Hydrocele and spermatocele	0.289	0.711
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.288	0.711
D05 Carcinoma in situ of breast	0.288	0.712
B95-B98 Bacterial, viral and other infectious agents	0.288	0.712
O32.1 Maternal care for breech presentation	0.288	0.712
N88 Other noninflammatory disorders of cervix uteri	0.288	0.712
M22.4 Chondromalacia patellae	0.288	0.712
O42.9 Premature rupture of membranes, unspecified	0.288	0.712
H34 Retinal vascular occlusions	0.287	0.712
N45 Orchitis and epididymitis	0.287	0.712
I20-I25 Ischaemic heart diseases	0.287	0.713
I50.9 Heart failure, unspecified	0.286	0.714
N51 Disorders of male genital organs in diseases classified elsewhere	0.286	0.714
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.286	0.714
N41 Inflammatory diseases of prostate	0.286	0.714
N46 Male infertility	0.286	0.714
N44 Torsion of testis	0.286	0.714
S06 Intracranial injury	0.285	0.714
M17.5 Other secondary gonarthrosis	0.285	0.715
M17.4 Other secondary gonarthrosis, bilateral	0.285	0.715
M17.3 Other posttraumatic gonarthrosis	0.285	0.715
M17.2 Posttraumatic gonarthrosis, bilateral	0.285	0.715
I78 Diseases of capillaries	0.283	0.717
M16.7 Other secondary coxarthrosis	0.283	0.717
M16.6 Other secondary coxarthrosis, bilateral	0.283	0.717
M16.5 Other posttraumatic coxarthrosis	0.283	0.717
M16.4 Posttraumatic coxarthrosis, bilateral	0.283	0.717
M16.3 Other dysplastic coxarthrosis	0.283	0.717
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.283	0.717
M16.0 Primary coxarthrosis, bilateral	0.283	0.717
S01 Open wound of head	0.282	0.718
M13 Other arthritis	0.282	0.718
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.282	0.718
I74 Arterial embolism and thrombosis	0.282	0.718
I72 Other aneurysm	0.282	0.718
I70 Atherosclerosis	0.282	0.718
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.282	0.718
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.281	0.719
N94.5 Secondary dysmenorrhoea	0.281	0.719
N94.4 Primary dysmenorrhoea	0.281	0.719
N94.3 Premenstrual tension syndrome	0.281	0.719
N94.2 Vaginismus	0.281	0.719
N94.0 Mittelschmerz	0.281	0.719
O26.8 Other specified pregnancy-related conditions	0.281	0.719
G80-G83 Cerebral palsy and other paralytic syndromes	0.281	0.719
O15 Eclampsia	0.280	0.719
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.280	0.719
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.280	0.719
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.280	0.719
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.280	0.719
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.280	0.719
M79.9 Soft tissue disorder, unspecified	0.280	0.720
M79.7 Fibromyalgia	0.280	0.720
M79.5 Residual foreign body in soft tissue	0.280	0.720
M79.4 Hypertrophy of (infrapatellar) fat pad	0.280	0.720
M79.3 Panniculitis, unspecified	0.280	0.720
M79.2 Neuralgia and neuritis, unspecified	0.280	0.720
M79.1 Myalgia	0.280	0.720
H33.0 Retinal detachment with retinal break	0.280	0.720
I42.8 Other cardiomyopathies	0.280	0.720
I42.7 Cardiomyopathy due to drugs and other external agents	0.280	0.720
I42.6 Alcoholic cardiomyopathy	0.280	0.720
I42.5 Other restrictive cardiomyopathy	0.280	0.720
I42.4 Endocardial fibroelastosis	0.280	0.720
I42.3 Endomyocardial (eosinophilic) disease	0.280	0.720
I42.2 Other hypertrophic cardiomyopathy	0.280	0.720
I42.1 Obstructive hypertrophic cardiomyopathy	0.280	0.720
H40-H42 Glaucoma	0.279	0.721
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.279	0.721
I34.8 Other nonrheumatic mitral valve disorders	0.279	0.721
I34.2 Nonrheumatic mitral (valve) stenosis	0.279	0.721
M79.0 Rheumatism, unspecified	0.279	0.721
N28 Other disorders of kidney and ureter, not elsewhere classified	0.279	0.721
Chapter XII Diseases of the skin and subcutaneous tissue	0.278	0.722
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.278	0.722
N76 Other inflammation of vagina and vulva	0.278	0.722
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.278	0.722
N71 Inflammatory disease of uterus, except cervix	0.278	0.722
N70 Salpingitis and oophoritis	0.278	0.722
I35.9 Aortic valve disorder, unspecified	0.278	0.722
I35.8 Other aortic valve disorders	0.278	0.722
I35.2 Aortic (valve) stenosis with insufficiency	0.278	0.722
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.278	0.722
O64.8 Obstructed labour due to other malposition and malpresentation	0.278	0.722
O64.5 Obstructed labour due to compound presentation	0.278	0.722
O64.4 Obstructed labour due to shoulder presentation	0.278	0.722
O64.3 Obstructed labour due to brow presentation	0.278	0.722
O64.2 Obstructed labour due to face presentation	0.278	0.722
O64.1 Obstructed labour due to breech presentation	0.278	0.722
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.277	0.722
O97 Death from sequelae of direct obstetric causes	0.277	0.722
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.277	0.722
O95 Obstetric death of unspecified cause	0.277	0.722
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.277	0.722
N85.0 Endometrial glandular hyperplasia	0.277	0.722
C50-C50 Malignant neoplasm of breast	0.277	0.723
I49.5 Sick sinus syndrome	0.277	0.723
I49.4 Other and unspecified premature depolarisation	0.277	0.723
I49.3 Ventricular premature depolarisation	0.277	0.723
I49.2 Junctional premature depolarisation	0.277	0.723
I49.1 Atrial premature depolarisation	0.277	0.723
I49.0 Ventricular fibrillation and flutter	0.277	0.723
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.276	0.724
I73.0 Raynaud's syndrome	0.276	0.724
C18.8 Overlapping lesion of colon	0.274	0.726
C18.6 Descending colon	0.274	0.726
C18.5 Splenic flexure	0.274	0.726
C18.4 Transverse colon	0.274	0.726
C18.3 Hepatic flexure	0.274	0.726
C18.1 Appendix	0.274	0.726
C18.0 Caecum	0.274	0.726
M19.9 Arthrosis, unspecified	0.274	0.726
O72.1 Other immediate postpartum haemorrhage	0.274	0.726
H35 Other retinal disorders	0.273	0.727
I84.2 Internal haemorrhoids without complication	0.273	0.727
H80-H83 Diseases of inner ear	0.272	0.728
I71 Aortic aneurysm and dissection	0.271	0.728
S52 Fracture of forearm	0.271	0.729
I44.2 Atrioventricular block, complete	0.271	0.729
H65-H75 Diseases of middle ear and mastoid	0.271	0.729
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.270	0.730
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.270	0.730
S09 Other and unspecified injuries of head	0.269	0.731
I46.9 Cardiac arrest, unspecified	0.269	0.731
I46.1 Sudden cardiac death, so described	0.269	0.731
N60.9 Benign mammary dysplasia, unspecified	0.268	0.732
N60.4 Mammary duct ectasia	0.268	0.732
N60.3 Fibrosclerosis of breast	0.268	0.732
N60.2 Fibroadenosis of breast	0.268	0.732
N60.0 Solitary cyst of breast	0.268	0.732
O03 Spontaneous abortion	0.268	0.732
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.267	0.732
I35.0 Aortic (valve) stenosis	0.266	0.734
G35 Multiple sclerosis	0.266	0.734
T85 Complications of other internal prosthetic devices, implants and grafts	0.266	0.734
K55-K64 Other diseases of intestines	0.266	0.734
B35-B49 Mycoses	0.266	0.734
M47.8 Other spondylosis	0.266	0.734
C77.3 Axillary and upper limb lymph nodes	0.266	0.734
N50 Other disorders of male genital organs	0.266	0.734
S08 Traumatic amputation of part of head	0.266	0.734
S07 Crushing injury of head	0.266	0.734
S05 Injury of eye and orbit	0.266	0.734
S04 Injury of cranial nerves	0.266	0.734
S03 Dislocation, sprain and strain of joints and ligaments of head	0.266	0.734
S02 Fracture of skull and facial bones	0.266	0.734
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.265	0.735
H33.2 Serous retinal detachment	0.265	0.735
G50-G59 Nerve, nerve root and plexus disorders	0.264	0.735
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.264	0.735
N27 Small kidney of unknown cause	0.264	0.735
N25 Disorders resulting from impaired renal tubular function	0.264	0.735
N26 Unspecified contracted kidney	0.264	0.735
A30-A49 Other bacterial diseases	0.264	0.736
M47.9 Spondylosis, unspecified	0.264	0.736
M79.67 Pain in limb (Ankle and foot)	0.264	0.736
H32 Chorioretinal disorders in diseases classified elsewhere	0.263	0.737
H31 Other disorders of choroid	0.263	0.737
H30 Chorioretinal inflammation	0.263	0.737
H60-H62 Diseases of external ear	0.263	0.737
N85.2 Hypertrophy of uterus	0.262	0.738
G40 Epilepsy	0.261	0.738
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.261	0.739
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.261	0.739
D46 Myelodysplastic syndromes	0.261	0.739
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.261	0.739
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.261	0.739
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.261	0.739
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.261	0.739
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.261	0.739
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.261	0.739
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.261	0.739
P90-P96 Other disorders originating in the perinatal period	0.261	0.739
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.261	0.739
P75-P78 Digestive system disorders of fetus and newborn	0.261	0.739
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.261	0.739
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.261	0.739
P35-P39 Infections specific to the perinatal period	0.261	0.739

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations