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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79395151
log Bayes Factor = 12.3279
Chromosome 16   position 22,272,027  (GRCh37) Explore rs79395151 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.995 0.005 0.000
W00-W19 Falls
0.994 0.006 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
W19 Unspecified fall
0.977 0.023 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.974 0.026 0.000
H53-H54 Visual disturbances and blindness
0.972 0.028 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
G90-G99 Other disorders of the nervous system
0.968 0.032 0.000
E87.5 Hyperkalaemia
0.956 0.044 0.000
Chapter I Certain infectious and parasitic diseases
0.952 0.048 0.000
S60-S69 Injuries to the wrist and hand
0.948 0.052 0.000
F10.2 Dependence syndrome
0.947 0.053 0.000
M45-M49 Spondylopathies
0.945 0.055 0.000
B95-B98 Bacterial, viral and other infectious agents
0.944 0.056 0.000
E20-E35 Disorders of other endocrine glands
0.944 0.056 0.000
M50-M54 Other dorsopathies
0.941 0.059 0.000
M05-M14 Inflammatory polyarthropathies
0.940 0.060 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.934 0.066 0.000
F10.0 Acute intoxication
0.928 0.072 0.000
M06 Other rheumatoid arthritis
0.926 0.074 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.922 0.078 0.000
M40-M43 Deforming dorsopathies
0.916 0.084 0.000
H54 Blindness and low vision
0.916 0.084 0.000
M06.9 Rheumatoid arthritis, unspecified
0.913 0.087 0.000
M51 Other intervertebral disk disorders
0.910 0.090 0.000
W19.9 Unspecified place
0.909 0.091 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.908 0.092 0.000
E23 Hypofunction and other disorders of pituitary gland
0.907 0.093 0.000
Chapter IX Diseases of the circulatory system
0.906 0.094 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.902 0.098 0.000
M84 Disorders of continuity of bone
0.901 0.099 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.900 0.100 0.000
M80 Osteoporosis with pathological fracture
0.900 0.100 0.000
G91 Hydrocephalus
0.898 0.102 0.000
E83 Disorders of mineral metabolism
0.893 0.107 0.000
E87.2 Acidosis
0.892 0.108 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.889 0.110 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.888 0.112 0.000
S70-S79 Injuries to the hip and thigh
0.888 0.112 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.887 0.113 0.000
M47 Spondylosis
0.884 0.116 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.883 0.117 0.000
F10.1 Harmful use
0.880 0.120 0.000
H53 Visual disturbances
0.880 0.120 0.000
W19.2 School, other institution and public administrative area
0.878 0.122 0.000
Chapter X Diseases of the respiratory system
0.873 0.127 0.000
E23.0 Hypopituitarism
0.872 0.128 0.000
S62 Fracture at wrist and hand level
0.868 0.132 0.000
Chapter II Neoplasms
0.868 0.132 0.000
E83.4 Disorders of magnesium metabolism
0.867 0.133 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.866 0.134 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
J40-J47 Chronic lower respiratory diseases
0.864 0.136 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.862 0.138 0.000
M47.9 Spondylosis, unspecified
0.860 0.140 0.000
E86 Volume depletion
0.860 0.140 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.860 0.140 0.000
H50 Other strabismus
0.859 0.141 0.000
M43 Other deforming dorsopathies
0.856 0.144 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.856 0.144 0.000
D00-D09 In situ neoplasms
0.855 0.145 0.000
W17 Other fall from one level to another
0.851 0.149 0.000
F41 Other anxiety disorders
0.851 0.149 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.851 0.149 0.000
F30-F39 Mood [affective] disorders
0.851 0.149 0.000
J44 Other chronic obstructive pulmonary disease
0.850 0.150 0.000
G40-G47 Episodic and paroxysmal disorders
0.849 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.847 0.153 0.000
H30-H36 Disorders of choroid and retina
0.846 0.154 0.000
I60-I69 Cerebrovascular diseases
0.845 0.155 0.000
H04 Disorders of lachrymal system
0.843 0.157 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.840 0.159 0.000
W18 Other fall on same level
0.831 0.169 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.829 0.171 0.000
G30-G32 Other degenerative diseases of the nervous system
0.829 0.171 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.829 0.171 0.000
W19.4 Street and highway
0.828 0.171 0.000
H10-H13 Disorders of conjunctiva
0.828 0.172 0.000
E85 Amyloidosis
0.828 0.172 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.827 0.173 0.000
M81 Osteoporosis without pathological fracture
0.825 0.175 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.823 0.177 0.000
M51.2 Other specified intervertebral disk displacement
0.821 0.179 0.000
S60 Superficial injury of wrist and hand
0.819 0.181 0.000
X50-X57 Overexertion, travel and privation
0.819 0.181 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.817 0.183 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.816 0.184 0.000
M60-M63 Disorders of muscles
0.814 0.186 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.807 0.193 0.000
W10 Fall on and from stairs and steps
0.807 0.193 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.807 0.193 0.000
F10.3 Withdrawal state
0.807 0.193 0.000
D05 Carcinoma in situ of breast
0.806 0.194 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.806 0.194 0.000
B35-B49 Mycoses
0.806 0.194 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.803 0.197 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.803 0.197 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.802 0.198 0.000
H54.4 Blindness, one eye
0.802 0.198 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.800 0.200 0.000
G91.9 Hydrocephalus, unspecified
0.799 0.201 0.000
S80-S89 Injuries to the knee and lower leg
0.799 0.201 0.000
I95 Hypotension
0.797 0.203 0.000
G20-G26 Extrapyramidal and movement disorders
0.797 0.203 0.000
M43.1 Spondylolisthesis
0.797 0.203 0.000
Chapter VIII Diseases of the ear and mastoid process
0.797 0.203 0.000
E73 Lactose intolerance
0.796 0.204 0.000
H53.0 Amblyopia ex anopsia
0.794 0.206 0.000
S10-S19 Injuries to the neck
0.790 0.210 0.000
W06 Fall involving bed
0.790 0.210 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.788 0.212 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.787 0.213 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.786 0.214 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.785 0.214 0.000
F41.9 Anxiety disorder, unspecified
0.784 0.216 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.782 0.217 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.782 0.218 0.000
M51.8 Other specified intervertebral disk disorders
0.782 0.218 0.000
D04 Carcinoma in situ of skin
0.782 0.218 0.000
F33 Recurrent depressive disorder
0.782 0.218 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.780 0.220 0.000
H49 Paralytic strabismus
0.779 0.221 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
I60 Subarachnoid haemorrhage
0.779 0.221 0.000
W50-W64 Exposure to animate mechanical forces
0.778 0.222 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.778 0.222 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.777 0.223 0.000
S79 Other and unspecified injuries of hip and thigh
0.777 0.223 0.000
D05.1 Intraductal carcinoma in situ
0.777 0.223 0.000
S00-S09 Injuries to the head
0.776 0.224 0.000
G47 Sleep disorders
0.776 0.224 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.775 0.225 0.000
J46 Status asthmaticus
0.771 0.229 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.770 0.230 0.000
W07 Fall involving chair
0.769 0.231 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.768 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.768 0.232 0.000
H18 Other disorders of cornea
0.768 0.232 0.000
M48 Other spondylopathies
0.768 0.232 0.000
I61 Intracerebral haemorrhage
0.767 0.233 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.766 0.234 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.766 0.234 0.000
I95.9 Hypotension, unspecified
0.766 0.234 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
M82 Osteoporosis in diseases classified elsewhere
0.764 0.236 0.000
M85 Other disorders of bone density and structure
0.763 0.237 0.000
I80 Phlebitis and thrombophlebitis
0.762 0.238 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.762 0.238 0.000
H54.9 Unspecified visual impairment (binocular)
0.762 0.238 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.762 0.238 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.757 0.243 0.000
G90 Disorders of autonomic nervous system
0.756 0.244 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.756 0.244 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.755 0.245 0.000
H54.7 Unspecified visual loss
0.754 0.246 0.000
I26 Pulmonary embolism
0.754 0.246 0.000
C45 Mesothelioma
0.754 0.246 0.000
T43.6 Psychostimulants with abuse potential
0.751 0.249 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.751 0.249 0.000
H21 Other disorders of iris and ciliary body
0.748 0.251 0.000
Y44 Agents primarily affecting blood constituents
0.747 0.253 0.000
E87.6 Hypokalaemia
0.747 0.253 0.000
S50-S59 Injuries to the elbow and forearm
0.746 0.254 0.000
H04.2 Epiphora
0.745 0.255 0.000
J42 Unspecified chronic bronchitis
0.744 0.256 0.000
S62.6 Fracture of other finger
0.743 0.257 0.000
M46 Other inflammatory spondylopathies
0.743 0.257 0.000
S09 Other and unspecified injuries of head
0.742 0.258 0.000
F43 Reaction to severe stress, and adjustment disorders
0.742 0.258 0.000
M06.4 Inflammatory polyarthropathy
0.742 0.258 0.000
H90-H95 Other disorders of ear
0.742 0.258 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.741 0.259 0.000
S65 Injury of blood vessels at wrist and hand level
0.740 0.260 0.000
V10-V19 Pedal cyclist injured in transport accident
0.739 0.261 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.739 0.261 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.739 0.261 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.739 0.261 0.000
B44 Aspergillosis
0.738 0.262 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.737 0.263 0.000
F11 Mental and behavioural disorders due to use of opioids
0.736 0.264 0.000
G95 Other diseases of spinal cord
0.736 0.264 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.736 0.264 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.736 0.264 0.000
G40 Epilepsy
0.733 0.267 0.000
I62 Other nontraumatic intracranial haemorrhage
0.733 0.267 0.000
F33.9 Recurrent depressive disorder, unspecified
0.733 0.267 0.000
V80-V89 Other land transport accidents
0.733 0.267 0.000
M91-M94 Chondropathies
0.732 0.268 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.730 0.270 0.000
G91.1 Obstructive hydrocephalus
0.730 0.270 0.000
C71 Malignant neoplasm of brain
0.730 0.270 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.729 0.271 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.729 0.271 0.000
M05 Seropositive rheumatoid arthritis
0.729 0.271 0.000
E26 Hyperaldosteronism
0.729 0.271 0.000
T43.2 Other and unspecified antidepressants
0.727 0.273 0.000
T58 Toxic effect of carbon monoxide
0.726 0.274 0.000
Y52 Agents primarily affecting the cardiovascular system
0.726 0.274 0.000
G03 Meningitis due to other and unspecified causes
0.725 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.275 0.000
Q80-Q89 Other congenital malformations
0.725 0.275 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.724 0.276 0.000
W17.2 School, other institution and public administrative area
0.723 0.277 0.000
E22 Hyperfunction of pituitary gland
0.722 0.278 0.000
W19.3 Sports and athletics area
0.722 0.278 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.722 0.278 0.000
F60-F69 Disorders of adult personality and behaviour
0.721 0.279 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.721 0.279 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.719 0.281 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.718 0.281 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.718 0.282 0.000
J09-J18 Influenza and pneumonia
0.718 0.282 0.000
S09.9 Unspecified injury of head
0.718 0.282 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.718 0.282 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
S62.3 Fracture of other metacarpal bone
0.715 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
H50.9 Strabismus, unspecified
0.714 0.286 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.714 0.286 0.000
E87.4 Mixed disorder of acid-base balance
0.713 0.286 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.713 0.287 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.713 0.287 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.713 0.287 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.713 0.287 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.713 0.287 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.713 0.287 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.712 0.288 0.000
W15 Fall from cliff
0.712 0.288 0.000
W14 Fall from tree
0.712 0.288 0.000
W12 Fall on and from scaffolding
0.712 0.288 0.000
W11 Fall on and from ladder
0.712 0.288 0.000
W09 Fall involving playground equipment
0.712 0.288 0.000
W05 Fall involving wheelchair
0.712 0.288 0.000
W04 Fall while being carried or supported by other persons
0.712 0.288 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.712 0.288 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.712 0.288 0.000
W00 Fall on same level involving ice and snow
0.712 0.288 0.000
G47.3 Sleep apnoea
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.712 0.288 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.711 0.289 0.000
H34 Retinal vascular occlusions
0.711 0.289 0.000
F39 Unspecified mood [affective] disorder
0.711 0.289 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.711 0.289 0.000
F10.9 Unspecified mental and behavioural disorder
0.710 0.290 0.000
F10.8 Other mental and behavioural disorders
0.710 0.290 0.000
F10.7 Residual and late-onset psychotic disorder
0.710 0.290 0.000
F10.6 Amnesic syndrome
0.710 0.290 0.000
F10.5 Psychotic disorder
0.710 0.290 0.000
E23.2 Diabetes insipidus
0.710 0.290 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.710 0.290 0.000
M54 Dorsalgia
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.709 0.291 0.000
H50.0 Convergent concomitant strabismus
0.708 0.292 0.000
S61 Open wound of wrist and hand
0.708 0.292 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.708 0.292 0.000
M83 Adult osteomalacia
0.707 0.293 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.707 0.293 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.707 0.293 0.000
Y57 Other and unspecified drugs and medicaments
0.707 0.293 0.000
F03 Unspecified dementia
0.706 0.294 0.000
G91.2 Normal-pressure hydrocephalus
0.705 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
M81.9 Osteoporosis, unspecified
0.704 0.296 0.000
S67 Crushing injury of wrist and hand
0.704 0.296 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
E34 Other endocrine disorders
0.702 0.298 0.000
F41.2 Mixed anxiety and depressive disorder
0.702 0.298 0.000
G96 Other disorders of central nervous system
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.700 0.299 0.000
W19.8 Other specified place
0.700 0.300 0.000
W19.5 Trade and service area
0.700 0.300 0.000
W19.0 Home
0.700 0.300 0.000
W19.7 Farm
0.700 0.300 0.000
W19.6 Industrial and construction area
0.700 0.300 0.000
W19.1 Residential institution
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
G93 Other disorders of brain
0.700 0.300 0.000
H55-H59 Other disorders of eye and adnexa
0.700 0.300 0.000
S62.5 Fracture of thumb
0.699 0.300 0.000
F17.1 Harmful use
0.699 0.301 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
S79.9 Unspecified injury of hip and thigh
0.698 0.302 0.000
H10 Conjunctivitis
0.698 0.302 0.000
S60.0 Contusion of finger(s) without damage to nail
0.697 0.303 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.697 0.303 0.000
M43.6 Torticollis
0.697 0.303 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
H43-H45 Disorders of vitreous body and globe
0.694 0.306 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.694 0.306 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.694 0.306 0.000
G92 Toxic encephalopathy
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.693 0.306 0.000
D03 Melanoma in situ
0.693 0.307 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.692 0.308 0.000
H50.2 Vertical strabismus
0.692 0.308 0.000
W18.3 Sports and athletics area
0.692 0.308 0.000
M51.9 Intervertebral disk disorder, unspecified
0.691 0.308 0.000
X51 Travel and motion
0.691 0.309 0.000
M20-M25 Other joint disorders
0.689 0.311 0.000
E29 Testicular dysfunction
0.689 0.311 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.688 0.312 0.000
S72 Fracture of femur
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.686 0.314 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.685 0.314 0.000
H53.2 Diplopia
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.684 0.316 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.684 0.316 0.000
H17 Corneal scars and opacities
0.683 0.317 0.000
B65-B83 Helminthiases
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
A15-A19 Tuberculosis
0.683 0.317 0.000
E24 Cushing's syndrome
0.682 0.318 0.000
C45.0 Mesothelioma of pleura
0.682 0.318 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.682 0.318 0.000
I63 Cerebral infarction
0.682 0.318 0.000
M62 Other disorders of muscle
0.681 0.319 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.681 0.319 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.319 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.680 0.319 0.000
E88 Other metabolic disorders
0.680 0.320 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.680 0.320 0.000
D04.5 Skin of trunk
0.680 0.320 0.000
H50.1 Divergent concomitant strabismus
0.679 0.321 0.000
C69 Malignant neoplasm of eye and adnexa
0.678 0.322 0.000
M49 Spondylopathies in diseases classified elsewhere
0.678 0.322 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.677 0.323 0.000
E32 Diseases of thymus
0.677 0.323 0.000
E31 Polyglandular dysfunction
0.677 0.323 0.000
E30 Disorders of puberty, not elsewhere classified
0.677 0.323 0.000
E25 Adrenogenital disorders
0.677 0.323 0.000
E20 Hypoparathyroidism
0.677 0.323 0.000
E50-E64 Other nutritional deficiencies
0.676 0.324 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.676 0.324 0.000
S20-S29 Injuries to the thorax
0.675 0.324 0.000
E28 Ovarian dysfunction
0.675 0.325 0.000
E83.5 Disorders of calcium metabolism
0.675 0.325 0.000
S62.2 Fracture of first metacarpal bone
0.675 0.325 0.000
E85.9 Amyloidosis, unspecified
0.674 0.325 0.000
W13 Fall from, out of or through building or structure
0.674 0.326 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
M12 Other specific arthropathies
0.674 0.326 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.674 0.326 0.000
M08 Juvenile arthritis
0.674 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.673 0.327 0.000
S70 Superficial injury of hip and thigh
0.672 0.328 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.670 0.330 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.669 0.331 0.000
T43.9 Psychotropic drug, unspecified
0.669 0.331 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.669 0.331 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.669 0.331 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.669 0.331 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.668 0.332 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.668 0.332 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.667 0.333 0.000
H53.1 Subjective visual disturbances
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.667 0.333 0.000
H54.0 Blindness, both eyes
0.666 0.334 0.000
F41.1 Generalised anxiety disorder
0.666 0.334 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.665 0.335 0.000
H53.8 Other visual disturbances
0.665 0.335 0.000
M06.8 Other specified rheumatoid arthritis
0.664 0.336 0.000
M06.2 Rheumatoid bursitis
0.664 0.336 0.000
M06.1 Adult-onset Still's disease
0.664 0.336 0.000
M06.0 Seronegative rheumatoid arthritis
0.664 0.336 0.000
G31.8 Other specified degenerative diseases of nervous system
0.664 0.336 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.663 0.337 0.000
H35 Other retinal disorders
0.663 0.337 0.000
H53.4 Visual field defects
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.662 0.338 0.000
W08 Fall involving other furniture
0.662 0.338 0.000
H51 Other disorders of binocular movement
0.661 0.339 0.000
Y43 Primarily systemic agents
0.661 0.339 0.000
W17.4 Street and highway
0.660 0.339 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.659 0.341 0.000
I81 Portal vein thrombosis
0.658 0.342 0.000
M41 Scoliosis
0.657 0.343 0.000
M42 Spinal osteochondrosis
0.657 0.343 0.000
M40 Kyphosis and lordosis
0.657 0.343 0.000
W10.4 Street and highway
0.657 0.343 0.000
H18.5 Hereditary corneal dystrophies
0.657 0.343 0.000
H54.6 Unqualified visual loss, one eye
0.656 0.343 0.000
H54.5 Low vision, one eye
0.656 0.343 0.000
H54.3 Unqualified visual loss, both eyes
0.656 0.343 0.000
H54.2 Low vision, both eyes
0.656 0.343 0.000
H54.1 Blindness, one eye, low vision, other eye
0.656 0.343 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.655 0.345 0.000
T90 Sequelae of injuries of head
0.655 0.345 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.655 0.345 0.000
S64 Injury of nerves at wrist and hand level
0.654 0.345 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.654 0.346 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.654 0.346 0.000
G25 Other extrapyramidal and movement disorders
0.654 0.346 0.000
M06.3 Rheumatoid nodule
0.654 0.346 0.000
C64-C68 Malignant neoplasms of urinary tract
0.653 0.347 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.653 0.347 0.000
S60.8 Other superficial injuries of wrist and hand
0.653 0.347 0.000
M51.3 Other specified intervertebral disk degeneration
0.652 0.347 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.652 0.347 0.000
M51.4 Schmorl's nodes
0.652 0.347 0.000
M65-M68 Disorders of synovium and tendon
0.653 0.347 0.000
H05 Disorders of orbit
0.652 0.348 0.000
E73.9 Lactose intolerance, unspecified
0.651 0.349 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.651 0.349 0.000
I89.0 Lymphoedema, not elsewhere classified
0.650 0.350 0.000
E23.7 Disorder of pituitary gland, unspecified
0.650 0.350 0.000
E23.6 Other disorders of pituitary gland
0.650 0.350 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.650 0.350 0.000
E23.1 Drug-induced hypopituitarism
0.650 0.350 0.000
Y44.2 Anticoagulants
0.650 0.350 0.000
E87.0 Hyperosmolality and hypernatraemia
0.650 0.350 0.000
I00-I02 Acute rheumatic fever
0.650 0.350 0.000
C45.9 Mesothelioma, unspecified
0.649 0.351 0.000
H04.8 Other disorders of lachrymal system
0.648 0.352 0.000
H49.2 Sixth [abducent] nerve palsy
0.647 0.353 0.000
H33 Retinal detachments and breaks
0.647 0.353 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.646 0.354 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.646 0.354 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.646 0.354 0.000
M84.9 Disorder of continuity of bone, unspecified
0.646 0.354 0.000
M84.8 Other disorders of continuity of bone
0.646 0.354 0.000
M84.4 Pathological fracture, not elsewhere classified
0.646 0.354 0.000
M84.3 Stress fracture, not elsewhere classified
0.646 0.354 0.000
M84.2 Delayed union of fracture
0.646 0.354 0.000
F48 Other neurotic disorders
0.645 0.355 0.000
F44 Dissociative [conversion] disorders
0.645 0.355 0.000
M80.8 Other osteoporosis with pathological fracture
0.645 0.355 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.645 0.355 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.645 0.355 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.645 0.355 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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