TreeWAS – Variant ID: rs6499270

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H26.9 Cataract, unspecified	0.000	0.000	1.000
E11.9 Without complications	0.000	0.062	0.938
M17.1 Other primary gonarthrosis	0.000	0.063	0.937
M17.9 Gonarthrosis, unspecified	0.000	0.069	0.931
M17 Gonarthrosis [arthrosis of knee]	0.000	0.072	0.928
E11 Non-insulin-dependent diabetes mellitus	0.000	0.124	0.876
E11.2 With renal complications	0.000	0.144	0.856
E11.4 With neurological complications	0.000	0.151	0.849
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.217	0.782
E11.6 With other specified complications	0.000	0.287	0.713
M17.5 Other secondary gonarthrosis	0.000	0.346	0.654
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.353	0.647
M17.3 Other posttraumatic gonarthrosis	0.000	0.353	0.647
E11.7 With multiple complications	0.000	0.372	0.628
E11.0 With coma	0.000	0.465	0.534
E11.8 With unspecified complications	0.000	0.499	0.501
E11.3 With ophthalmic complications	0.000	0.509	0.491
E11.1 With ketoacidosis	0.000	0.538	0.462
E11.5 With peripheral circulatory complications	0.000	0.665	0.335
M20.1 Hallux valgus (acquired)	0.304	0.696	0.000
M20 Acquired deformities of fingers and toes	0.293	0.707	0.000
M20.5 Other deformities of toe(s) (acquired)	0.289	0.711	0.000
M20.3 Other deformity of hallux (acquired)	0.284	0.716	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.272	0.728	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.751	0.249
E10-E14 Diabetes mellitus	0.000	0.777	0.223
E14 Unspecified diabetes mellitus	0.000	0.817	0.183
E14.9 Without complications	0.000	0.825	0.175
M20.4 Other hammer toe(s) (acquired)	0.175	0.825	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.840	0.160
E14.2 Withrenal complications	0.000	0.850	0.150
M10.99 Gout, unspecified (Site unspecified)	0.000	0.853	0.147
E13 Other specified diabetes mellitus	0.000	0.864	0.136
E14.7 With multiple complications	0.000	0.868	0.131
E14.5 With peripheral circulatory complications	0.000	0.870	0.129
E14.6 With other specified complications	0.000	0.873	0.127
E14.0 With coma	0.000	0.876	0.124
E14.1 With ketoacidosis	0.000	0.880	0.120
E14.8 With unspecified complications	0.000	0.881	0.119
E12.9 Without complications	0.000	0.885	0.115
E12.8 With unspecified complications	0.000	0.885	0.115
E12.7 With multiple complications	0.000	0.885	0.115
E12.6 With other specified complications	0.000	0.885	0.115
E12.5 With peripheral circulatory complications	0.000	0.885	0.115
E12.4 With neurological complications	0.000	0.885	0.115
E12.3 With ophthalmic complications	0.000	0.885	0.115
E12.2 With renal complications	0.000	0.885	0.115
E12.1 With ketoacidosis	0.000	0.885	0.115
E12.0 With coma	0.000	0.885	0.115
I42.0 Dilated cardiomyopathy	0.000	0.890	0.110
E14.4 With neurological complications	0.000	0.898	0.102
E13.8 With unspecified complications	0.000	0.902	0.097
E13.7 With multiple complications	0.000	0.902	0.097
E13.6 With other specified complications	0.000	0.902	0.097
E13.5 With peripheral circulatory complications	0.000	0.902	0.097
E13.4 With neurological complications	0.000	0.902	0.097
E13.2 With renal complications	0.000	0.902	0.097
E13.1 With ketoacidosis	0.000	0.902	0.097
E13.0 With coma	0.000	0.902	0.097
K80 Cholelithiasis	0.000	0.903	0.097
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.903	0.097
E14.3 With ophthalmic complications	0.000	0.903	0.097
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.909	0.091
K80.4 Calculus of bile duct with cholecystitis	0.000	0.909	0.091
E13.3 With ophthalmic complications	0.000	0.911	0.088
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.914	0.086
E13.9 Without complications	0.000	0.915	0.085
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.917	0.083
K80.3 Calculus of bile duct with cholangitis	0.000	0.930	0.070
I42 Cardiomyopathy	0.000	0.946	0.054
H26 Other cataract	0.000	0.948	0.052
E10 Insulin-dependent diabetes mellitus	0.000	0.949	0.051
K80.8 Other cholelithiasis	0.000	0.949	0.051
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.949	0.050
M20.0 Deformity of finger(s)	0.048	0.951	0.001
I50 Heart failure	0.000	0.951	0.049
I50.9 Heart failure, unspecified	0.000	0.952	0.048
I35 Nonrheumatic aortic valve disorders	0.000	0.952	0.048
I30-I52 Other forms of heart disease	0.000	0.953	0.047
I35.1 Aortic (valve) insufficiency	0.000	0.954	0.046
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.954	0.046
I44.7 Left bundle-branch block, unspecified	0.000	0.954	0.046
I50.0 Congestive heart failure	0.000	0.955	0.045
I30 Acute pericarditis	0.000	0.956	0.044
I44 Atrioventricular and left bundle-branch block	0.000	0.956	0.044
I42.6 Alcoholic cardiomyopathy	0.000	0.957	0.043
E10.8 With unspecified complications	0.000	0.958	0.042
E10.9 Without complications	0.000	0.958	0.042
I30.9 Acute pericarditis, unspecified	0.000	0.959	0.041
I42.4 Endocardial fibroelastosis	0.000	0.959	0.041
E10.0 With coma	0.000	0.960	0.040
I36 Nonrheumatic tricuspid valve disorders	0.000	0.960	0.040
E10.2 With renal complications	0.000	0.960	0.040
H26.0 Infantile, juvenile and presenile cataract	0.000	0.961	0.039
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.961	0.039
I42.5 Other restrictive cardiomyopathy	0.000	0.961	0.039
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.961	0.039
I35.8 Other aortic valve disorders	0.000	0.961	0.039
I42.9 Cardiomyopathy, unspecified	0.000	0.962	0.038
I44.2 Atrioventricular block, complete	0.000	0.962	0.038
I51 Complications and ill-defined descriptions of heart disease	0.000	0.964	0.036
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.965	0.035
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.965	0.035
H26.3 Drug-induced cataract	0.000	0.965	0.035
E10.7 With multiple complications	0.000	0.965	0.035
I30.1 Infective pericarditis	0.000	0.965	0.035
I52 Other heart disorders in diseases classified elsewhere	0.000	0.966	0.034
I48 Atrial fibrillation and flutter	0.000	0.966	0.034
I41 Myocarditis in diseases classified elsewhere	0.000	0.966	0.034
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.966	0.034
I32 Pericarditis in diseases classified elsewhere	0.000	0.966	0.034
I44.4 Left anterior fascicular block	0.000	0.966	0.034
I40 Acute myocarditis	0.000	0.968	0.032
I42.8 Other cardiomyopathies	0.000	0.968	0.032
I37 Pulmonary valve disorders	0.000	0.968	0.032
I30.8 Other forms of acute pericarditis	0.000	0.968	0.032
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.968	0.032
I44.5 Left posterior fascicular block	0.000	0.968	0.032
H26.1 Traumatic cataract	0.000	0.968	0.032
I50.1 Left ventricular failure	0.000	0.968	0.032
I46 Cardiac arrest	0.000	0.969	0.031
I44.6 Other and unspecified fascicular block	0.000	0.969	0.031
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.969	0.031
I35.9 Aortic valve disorder, unspecified	0.000	0.969	0.031
I51.6 Cardiovascular disease, unspecified	0.000	0.971	0.029
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.971	0.029
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.971	0.029
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.971	0.029
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.971	0.029
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.971	0.029
E10.1 With ketoacidosis	0.000	0.971	0.029
I51.7 Cardiomegaly	0.000	0.971	0.029
E65-E68 Obesity and other hyperalimentation	0.000	0.972	0.028
E40-E46 Malnutrition	0.000	0.972	0.028
I51.5 Myocardial degeneration	0.000	0.972	0.028
E46 Unspecified protein-energy malnutrition	0.000	0.972	0.028
T78.3 Angioneurotic oedema	0.028	0.972	0.000
E65 Localised adiposity	0.000	0.972	0.028
I33 Acute and subacute endocarditis	0.000	0.973	0.027
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.973	0.027
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.973	0.027
I51.0 Cardiac septal defect, acquired	0.000	0.974	0.026
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.974	0.026
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.974	0.026
I46.0 Cardiac arrest with successful resuscitation	0.000	0.974	0.026
K83 Other diseases of biliary tract	0.000	0.974	0.026
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.974	0.025
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.974	0.025
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.974	0.025
I44.3 Other and unspecified atrioventricular block	0.000	0.974	0.025
E10.4 With neurological complications	0.000	0.974	0.025
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.975	0.025
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.975	0.025
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.975	0.025
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.975	0.025
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.975	0.025
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.975	0.025
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.975	0.025
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.975	0.025
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.975	0.025
I48.4 Atypical atrial flutter	0.000	0.975	0.025
I48.3 Typical atrial flutter	0.000	0.975	0.025
I48.2 Chronic atrial fibrillation	0.000	0.975	0.025
I48.1 Persistent atrial fibrillation	0.000	0.975	0.025
I48.0 Paroxysmal atrial fibrillation	0.000	0.975	0.025
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.975	0.025
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.975	0.025
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.975	0.025
I40.9 Acute myocarditis, unspecified	0.000	0.975	0.025
I51.4 Myocarditis, unspecified	0.000	0.976	0.024
K83.1 Obstruction of bile duct	0.000	0.976	0.024
H26.2 Complicated cataract	0.000	0.976	0.024
I40.8 Other acute myocarditis	0.000	0.977	0.023
I40.1 Isolated myocarditis	0.000	0.977	0.023
I35.0 Aortic (valve) stenosis	0.000	0.977	0.023
I37.9 Pulmonary valve disorder, unspecified	0.000	0.977	0.023
I37.8 Other pulmonary valve disorders	0.000	0.977	0.023
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.977	0.023
I45 Other conduction disorders	0.000	0.977	0.023
K83.0 Cholangitis	0.000	0.977	0.023
I46.1 Sudden cardiac death, so described	0.000	0.977	0.023
I33.9 Acute endocarditis, unspecified	0.000	0.978	0.022
I37.1 Pulmonary valve insufficiency	0.000	0.978	0.022
E66 Obesity	0.000	0.978	0.022
I31 Other diseases of pericardium	0.000	0.978	0.022
I37.0 Pulmonary valve stenosis	0.000	0.978	0.022
K85 Acute pancreatitis	0.000	0.979	0.021
E10.6 With other specified complications	0.001	0.979	0.021
E10.5 With peripheral circulatory complications	0.000	0.979	0.021
T78 Adverse effects, not elsewhere classified	0.021	0.979	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.979	0.021
C71.9 Brain, unspecified	0.021	0.979	0.000
M20.2 Hallux rigidus	0.021	0.979	0.000
E67 Other hyperalimentation	0.000	0.979	0.020
E68 Sequelae of hyperalimentation	0.000	0.979	0.020
K83.9 Disease of biliary tract, unspecified	0.000	0.979	0.021
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.979	0.021
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.980	0.020
E45 Retarded development following protein-energy malnutrition	0.000	0.980	0.020
E43 Unspecified severe protein-energy malnutrition	0.000	0.980	0.020
E42 Marasmic kwashiorkor	0.000	0.980	0.020
E41 Nutritional marasmus	0.000	0.980	0.020
E40 Kwashiorkor	0.000	0.980	0.020
T78.1 Other adverse food reactions, not elsewhere classified	0.020	0.980	0.000
H26.8 Other specified cataract	0.000	0.980	0.020
I45.9 Conduction disorder, unspecified	0.000	0.980	0.020
C71 Malignant neoplasm of brain	0.020	0.980	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.980	0.019
K85.9 Acute pancreatitis, unspecified	0.000	0.981	0.019
I40.0 Infective myocarditis	0.000	0.981	0.019
C71.2 Temporal lobe	0.019	0.981	0.000
K83.3 Fistula of bile duct	0.000	0.981	0.019
K83.8 Other specified diseases of biliary tract	0.000	0.981	0.019
K83.2 Perforation of bile duct	0.000	0.982	0.018
I51.9 Heart disease, unspecified	0.000	0.982	0.018
I44.1 Atrioventricular block, second degree	0.000	0.982	0.018
N89.8 Other specified noninflammatory disorders of vagina	0.018	0.982	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.982	0.018
I51.8 Other ill-defined heart diseases	0.000	0.982	0.018
I45.5 Other specified heart block	0.000	0.982	0.018
K85.2 Alcohol-induced acute pancreatitis	0.000	0.982	0.018
I42.2 Other hypertrophic cardiomyopathy	0.000	0.983	0.017
K83.4 Spasm of sphincter of Oddi	0.000	0.983	0.017
I45.8 Other specified conduction disorders	0.000	0.983	0.017
T78.2 Anaphylactic shock, unspecified	0.017	0.983	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.983	0.017
K83.5 Biliary cyst	0.000	0.984	0.016
C71.0 Cerebrum, except lobes and ventricles	0.016	0.984	0.000
E66.1 Drug-induced obesity	0.000	0.984	0.016
I31.0 Chronic adhesive pericarditis	0.000	0.984	0.016
I45.4 Nonspecific intraventricular block	0.000	0.984	0.016
I31.8 Other specified diseases of pericardium	0.000	0.984	0.016
I31.2 Haemopericardium, not elsewhere classified	0.000	0.984	0.016
M48.02 Spinal stenosis (Cervical region)	0.000	0.984	0.016
E66.0 Obesity due to excess calories	0.000	0.984	0.016
I95.1 Orthostatic hypotension	0.000	0.984	0.016
C71.5 Cerebral ventricle	0.015	0.984	0.000
C71.6 Cerebellum	0.015	0.984	0.000
K85.3 Drug-induced acute pancreatitis	0.000	0.985	0.015
C71.8 Overlapping lesion of brain	0.015	0.985	0.000
I45.2 Bifascicular block	0.000	0.985	0.015
K85.0 Idiopathic acute pancreatitis	0.000	0.985	0.015
C71.4 Occipital lobe	0.015	0.985	0.000
E67.8 Other specified hyperalimentation	0.000	0.985	0.015
E67.3 Hypervitaminosis D	0.000	0.985	0.015
E67.2 Megavitamin-B6 syndrome	0.000	0.985	0.015
E67.1 Hypercarotenaemia	0.000	0.985	0.015
E67.0 Hypervitaminosis A	0.000	0.985	0.015
I45.6 Preexcitation syndrome	0.000	0.985	0.015
E44.1 Mild protein-energy malnutrition	0.000	0.985	0.015
E44.0 Moderate protein-energy malnutrition	0.000	0.985	0.015
I45.0 Right fascicular block	0.000	0.985	0.015
T78.9 Adverse effect, unspecified	0.015	0.985	0.000
E10.3 With ophthalmic complications	0.000	0.985	0.014
H26.4 After-cataract	0.000	0.985	0.015
I31.9 Disease of pericardium, unspecified	0.000	0.986	0.014
K86.9 Disease of pancreas, unspecified	0.000	0.986	0.014
T78.0 Anaphylactic shock due to adverse food reaction	0.014	0.986	0.000
C71.1 Frontal lobe	0.014	0.986	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.986	0.014
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.986	0.014
K86 Other diseases of pancreas	0.000	0.986	0.014
M15-M19 Arthrosis	0.000	0.986	0.014
K85.8 Other acute pancreatitis	0.000	0.986	0.014
C71.7 Brain stem	0.014	0.986	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.986	0.014
C71.3 Parietal lobe	0.014	0.986	0.000
E66.8 Other obesity	0.000	0.986	0.014
E15 Nondiabetic hypoglycaemic coma	0.000	0.987	0.013
I95.2 Hypotension due to drugs	0.000	0.987	0.013
E66.9 Obesity, unspecified	0.000	0.987	0.013
I44.0 Atrioventricular block, first degree	0.000	0.987	0.013
M10.9 Gout, unspecified	0.000	0.987	0.013
I95 Hypotension	0.000	0.987	0.013
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.987	0.013
K86.8 Other specified diseases of pancreas	0.000	0.987	0.013
T78.8 Other adverse effects, not elsewhere classified	0.012	0.988	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.988	0.012
I34 Nonrheumatic mitral valve disorders	0.000	0.988	0.012
T78.4 Allergy, unspecified	0.012	0.988	0.000
I45.3 Trifascicular block	0.000	0.988	0.011
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.989	0.011
D32.9 Meninges, unspecified	0.011	0.989	0.000
K81 Cholecystitis	0.000	0.989	0.011
K85.1 Biliary acute pancreatitis	0.000	0.989	0.011
T66-T78 Other and unspecified effects of external causes	0.011	0.989	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.989	0.011
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.989	0.011
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.989	0.011
E16 Other disorders of pancreatic internal secretion	0.000	0.990	0.010
M10.93 Gout, unspecified (Forearm)	0.000	0.990	0.010
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.010	0.990	0.000
M10.98 Gout, unspecified (Other)	0.000	0.990	0.009
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.990	0.009
M10.91 Gout, unspecified (Shoulder region)	0.000	0.990	0.009
T71 Asphyxiation	0.009	0.991	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.991	0.009
T68 Hypothermia	0.009	0.991	0.000
I95.0 Idiopathic hypotension	0.000	0.991	0.009
M10.94 Gout, unspecified (Hand)	0.000	0.991	0.008
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.992	0.008
T73 Effects of other deprivation	0.008	0.992	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.008	0.992	0.000
I38 Endocarditis, valve unspecified	0.000	0.992	0.008
I10-I15 Hypertensive diseases	0.000	0.992	0.008
T74 Maltreatment syndromes	0.008	0.992	0.000
T69 Other effects of reduced temperature	0.008	0.992	0.000
T67 Effects of heat and light	0.008	0.992	0.000
K56.7 Ileus, unspecified	0.000	0.992	0.008
I15 Secondary hypertension	0.000	0.992	0.008
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.992	0.008
I95.8 Other hypotension	0.000	0.992	0.008
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.992	0.008
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.992	0.008
I98.0 Cardiovascular syphilis	0.000	0.992	0.008
Chapter IX Diseases of the circulatory system	0.000	0.992	0.008
I10 Essential (primary) hypertension	0.000	0.992	0.008
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.992	0.008
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.992	0.008
I34.0 Mitral (valve) insufficiency	0.000	0.992	0.008
M10.90 Gout, unspecified (Multiple sites)	0.000	0.992	0.007
I97.1 Other functional disturbances following cardiac surgery	0.000	0.992	0.007
K81.0 Acute cholecystitis	0.000	0.992	0.008
T66 Unspecified effects of radiation	0.007	0.993	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.993	0.007
I05 Rheumatic mitral valve diseases	0.000	0.993	0.007
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.993	0.007
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.993	0.007
E16.4 Abnormal secretion of gastrin	0.000	0.993	0.007
E16.3 Increased secretion of glucagon	0.000	0.993	0.007
I05.9 Mitral valve disease, unspecified	0.000	0.993	0.007
T75 Effects of other external causes	0.007	0.993	0.000
E00-E07 Disorders of thyroid gland	0.000	0.993	0.007
C72.0 Spinal cord	0.007	0.993	0.000
K81.8 Other cholecystitis	0.000	0.993	0.007
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
K81.1 Chronic cholecystitis	0.000	0.993	0.007
I47 Paroxysmal tachycardia	0.000	0.993	0.007
M10.92 Gout, unspecified (Upper arm)	0.000	0.993	0.007
I05.1 Rheumatic mitral insufficiency	0.000	0.993	0.007
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.993	0.007
T70 Effects of air pressure and water pressure	0.007	0.993	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.993	0.007
M15 Polyarthrosis	0.000	0.993	0.007
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.993	0.007
E05.9 Thyrotoxicosis, unspecified	0.000	0.993	0.007
C69.3 Choroid	0.007	0.993	0.000
I11 Hypertensive heart disease	0.000	0.993	0.007
T73.3 Exhaustion due to excessive exertion	0.007	0.993	0.000
C70 Malignant neoplasm of meninges	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.000	0.993	0.007
E50-E64 Other nutritional deficiencies	0.000	0.993	0.007
E27.8 Other specified disorders of adrenal gland	0.000	0.993	0.007
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.993	0.006
I97.0 Postcardiotomy syndrome	0.000	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.994	0.006
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.994	0.006
E16.1 Other hypoglycaemia	0.000	0.994	0.006
K86.3 Pseudocyst of pancreas	0.000	0.994	0.006
T73.9 Effect of deprivation, unspecified	0.006	0.994	0.000
T73.8 Other effects of deprivation	0.006	0.994	0.000
T73.2 Exhaustion due to exposure	0.006	0.994	0.000
T73.1 Effects of thirst	0.006	0.994	0.000
T73.0 Effects of hunger	0.006	0.994	0.000
C72.9 Central nervous system, unspecified	0.006	0.994	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.006	0.994	0.000
C72.5 Other and unspecified cranial nerves	0.006	0.994	0.000
C72.4 Acoustic nerve	0.006	0.994	0.000
C72.3 Optic nerve	0.006	0.994	0.000
C72.2 Olfactory nerve	0.006	0.994	0.000
C72.1 Cauda equina	0.006	0.994	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.994	0.006
I05-I09 Chronic rheumatic heart diseases	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
I13 Hypertensive heart and renal disease	0.000	0.994	0.006
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.994	0.006
T67.9 Effects of heat and light, unspecified	0.006	0.994	0.000
T67.8 Other effects of heat and light	0.006	0.994	0.000
T67.7 Heat oedema	0.006	0.994	0.000
T67.6 Heat fatigue, transient	0.006	0.994	0.000
T67.5 Heat exhaustion, unspecified	0.006	0.994	0.000
T67.4 Heat exhaustion due to salt depletion	0.006	0.994	0.000
T67.3 Heat exhaustion, anhydrotic	0.006	0.994	0.000
T67.2 Heat cramp	0.006	0.994	0.000
T67.1 Heat syncope	0.006	0.994	0.000
T67.0 Heatstroke and sunstroke	0.006	0.994	0.000
T69.9 Effect of reduced temperature, unspecified	0.006	0.994	0.000
T69.8 Other specified effects of reduced temperature	0.006	0.994	0.000
T69.1 Chilblains	0.006	0.994	0.000
T69.0 Immersion hand and foot	0.006	0.994	0.000
T74.9 Maltreatment syndrome, unspecified	0.006	0.994	0.000
T74.8 Other maltreatment syndromes	0.006	0.994	0.000
T74.3 Psychological abuse	0.006	0.994	0.000
T74.2 Sexual abuse	0.006	0.994	0.000
T74.1 Physical abuse	0.006	0.994	0.000
T74.0 Neglect or abandonment	0.006	0.994	0.000
I15.8 Other secondary hypertension	0.000	0.994	0.006
I15.2 Hypertension secondary to endocrine disorders	0.000	0.994	0.006
I05.2 Mitral stenosis with insufficiency	0.000	0.994	0.006
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.994	0.006
M10.96 Gout, unspecified (Lower leg)	0.000	0.994	0.006
C69.2 Retina	0.006	0.994	0.000
I00-I02 Acute rheumatic fever	0.000	0.994	0.006
I15.0 Renovascular hypertension	0.000	0.994	0.006
T43.2 Other and unspecified antidepressants	0.000	0.994	0.006
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.994	0.006
T75.1 Drowning and nonfatal submersion	0.005	0.994	0.000
E07 Other disorders of thyroid	0.000	0.994	0.006
C69.4 Ciliary body	0.005	0.994	0.000
T75.8 Other specified effects of external causes	0.005	0.994	0.000
T75.3 Motion sickness	0.005	0.994	0.000
T75.2 Effects of vibration	0.005	0.994	0.000
T75.0 Effects of lightning	0.005	0.994	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.994	0.005
E00 Congenital iodine-deficiency syndrome	0.000	0.994	0.005
C69.8 Overlapping lesion of eye and adnexa	0.005	0.994	0.000
C69.5 Lachrymal gland and duct	0.005	0.994	0.000
C69.1 Cornea	0.005	0.994	0.000
I05.0 Mitral stenosis	0.000	0.994	0.005
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.005
I05.8 Other mitral valve diseases	0.000	0.995	0.005
I33.0 Acute and subacute infective endocarditis	0.001	0.995	0.005
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.995	0.005
E23 Hypofunction and other disorders of pituitary gland	0.000	0.995	0.005
T70.9 Effect of air pressure and water pressure, unspecified	0.005	0.995	0.000
T70.8 Other effects of air pressure and water pressure	0.005	0.995	0.000
T70.4 Effects of high-pressure fluids	0.005	0.995	0.000
T70.2 Other and unspecified effects of high altitude	0.005	0.995	0.000
T70.1 Sinus barotrauma	0.005	0.995	0.000
T70.0 Otitic barotrauma	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.995	0.005
M15.0 Primary generalised (osteo)arthrosis	0.000	0.995	0.005
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.995	0.005
M15.3 Secondary multiple arthrosis	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
K81.9 Cholecystitis, unspecified	0.000	0.995	0.005
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.995	0.005
R30.0 Dysuria	0.005	0.995	0.000
E05.8 Other thyrotoxicosis	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
M15.4 Erosive (osteo)arthrosis	0.000	0.995	0.005
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.995	0.005
E63 Other nutritional deficiencies	0.000	0.995	0.005
E50 Vitamin A deficiency	0.000	0.995	0.005
E60 Dietary zinc deficiency	0.000	0.995	0.005
E59 Dietary selenium deficiency	0.000	0.995	0.005
E54 Ascorbic acid deficiency	0.000	0.995	0.005
E52 Niacin deficiency [pellagra]	0.000	0.995	0.005
H25-H28 Disorders of lens	0.000	0.995	0.005
E07.8 Other specified disorders of thyroid	0.000	0.995	0.005
M15.9 Polyarthrosis, unspecified	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
C69.0 Conjunctiva	0.005	0.995	0.000
I47.0 Reentry ventricular arrhythmia	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.000	0.995	0.005
E05.5 Thyroid crisis or storm	0.000	0.995	0.005
E05.4 Thyrotoxicosis factitia	0.000	0.995	0.005
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.995	0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.995	0.005
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.995	0.005
E24 Cushing's syndrome	0.000	0.995	0.005
E25 Adrenogenital disorders	0.000	0.995	0.005
M15.8 Other polyarthrosis	0.000	0.995	0.004
T75.4 Effects of electric current	0.004	0.995	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.995	0.004
E56 Other vitamin deficiencies	0.000	0.995	0.004
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.995	0.004
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.995	0.004
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.995	0.004
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.995	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
I49 Other cardiac arrhythmias	0.000	0.995	0.005
I49.4 Other and unspecified premature depolarisation	0.000	0.995	0.005
C69.6 Orbit	0.004	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
E26 Hyperaldosteronism	0.000	0.995	0.004
E16.2 Hypoglycaemia, unspecified	0.000	0.995	0.005
E51 Thiamine deficiency	0.000	0.995	0.004
C70.0 Cerebral meninges	0.004	0.995	0.000
I02 Rheumatic chorea	0.000	0.996	0.004
I01 Rheumatic fever with heart involvement	0.000	0.996	0.004
E58 Dietary calcium deficiency	0.000	0.996	0.004
I00 Rheumatic fever without mention of heart involvement	0.000	0.996	0.004
I06 Rheumatic aortic valve diseases	0.000	0.996	0.004
K86.1 Other chronic pancreatitis	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations