TreeWAS – Variant ID: rs117331002

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
H53-H54 Visual disturbances and blindness	0.999	0.001
H53 Visual disturbances	0.999	0.001
H53.2 Diplopia	0.996	0.004
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.995	0.005
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.994	0.006
R26 Abnormalities of gait and mobility	0.992	0.008
Chapter XI Diseases of the digestive system	0.986	0.014
Chapter X Diseases of the respiratory system	0.985	0.015
G90-G99 Other disorders of the nervous system	0.985	0.015
K60.2 Anal fissure, unspecified	0.985	0.015
K55-K64 Other diseases of intestines	0.984	0.016
K60 Fissure and fistula of anal and rectal regions	0.984	0.016
R26.8 Other and unspecified abnormalities of gait and mobility	0.983	0.017
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.980	0.020
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.975	0.025
G80-G83 Cerebral palsy and other paralytic syndromes	0.960	0.040
H53.9 Visual disturbance, unspecified	0.959	0.041
R25 Abnormal involuntary movements	0.958	0.042
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.954	0.046
R50-R69 General symptoms and signs	0.951	0.049
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.950	0.050
J60-J70 Lung diseases due to external agents	0.948	0.052
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.947	0.053
K63 Other diseases of intestine	0.945	0.055
G93 Other disorders of brain	0.935	0.065
J00-J06 Acute upper respiratory infections	0.932	0.068
S00-S09 Injuries to the head	0.932	0.068
Chapter XX External causes of morbidity and mortality	0.928	0.072
T79-T79 Certain early complications of trauma	0.926	0.074
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.921	0.079
Chapter V Mental and behavioural disorders	0.917	0.083
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.913	0.087
H49 Paralytic strabismus	0.912	0.088
J80-J84 Other respiratory diseases principally affecting the interstitium	0.911	0.089
G00-G09 Inflammatory diseases of the central nervous system	0.907	0.093
R26.3 Immobility	0.903	0.097
H53.0 Amblyopia ex anopsia	0.902	0.098
R52 Pain, not elsewhere classified	0.901	0.099
H50 Other strabismus	0.893	0.107
J02 Acute pharyngitis	0.892	0.108
H55-H59 Other disorders of eye and adnexa	0.890	0.110
R25.2 Cramp and spasm	0.890	0.110
G82 Paraplegia and tetraplegia	0.888	0.112
T79 Certain early complications of trauma, not elsewhere classified	0.887	0.113
T66-T78 Other and unspecified effects of external causes	0.887	0.113
H43-H45 Disorders of vitreous body and globe	0.879	0.121
R30-R39 Symptoms and signs involving the urinary system	0.878	0.122
Y88 Sequelae of surgical and medical care as external cause	0.872	0.128
T91 Sequelae of injuries of neck and trunk	0.872	0.128
R39 Other symptoms and signs involving the urinary system	0.871	0.129
G95 Other diseases of spinal cord	0.870	0.130
J84 Other interstitial pulmonary diseases	0.869	0.131
G83 Other paralytic syndromes	0.867	0.133
S02 Fracture of skull and facial bones	0.866	0.134
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.866	0.134
R25.8 Other and unspecified abnormal involuntary movements	0.864	0.136
J02.9 Acute pharyngitis, unspecified	0.862	0.138
R52.1 Chronic intractable pain	0.862	0.138
R53 Malaise and fatigue	0.862	0.138
G12 Spinal muscular atrophy and related syndromes	0.861	0.139
R39.1 Other difficulties with micturition	0.860	0.140
K50-K52 Noninfective enteritis and colitis	0.859	0.141
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.857	0.143
R51 Headache	0.857	0.143
R42 Dizziness and giddiness	0.855	0.145
K63.3 Ulcer of intestine	0.855	0.145
K01 Embedded and impacted teeth	0.854	0.146
G93.1 Anoxic brain damage, not elsewhere classified	0.848	0.152
H55 Nystagmus and other irregular eye movements	0.847	0.153
G70-G73 Diseases of myoneural junction and muscle	0.844	0.156
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.843	0.157
F30-F39 Mood [affective] disorders	0.837	0.163
Y86 Sequelae of other accidents	0.834	0.166
G30-G32 Other degenerative diseases of the nervous system	0.834	0.166
T90 Sequelae of injuries of head	0.834	0.166
K63.5 Polyp of colon	0.834	0.166
H53.8 Other visual disturbances	0.834	0.166
G93.3 Postviral fatigue syndrome	0.833	0.167
K05 Gingivitis and periodontal diseases	0.828	0.172
H49.0 Third [oculomotor] nerve palsy	0.825	0.175
K13 Other diseases of lip and oral mucosa	0.824	0.176
S01 Open wound of head	0.822	0.178
T20-T25 Burns and corrosions of external body surface, specified by site	0.821	0.179
G12.2 Motor neuron disease	0.818	0.181
K02 Dental caries	0.818	0.182
F33 Recurrent depressive disorder	0.814	0.186
T79.3 Post-traumatic wound infection, not elsewhere classified	0.813	0.187
G90 Disorders of autonomic nervous system	0.812	0.188
J69 Pneumonitis due to solids and liquids	0.811	0.188
S70-S79 Injuries to the hip and thigh	0.811	0.189
R41 Other symptoms and signs involving cognitive functions and awareness	0.811	0.189
K60.4 Rectal fistula	0.810	0.190
H50.1 Divergent concomitant strabismus	0.804	0.196
K01.1 Impacted teeth	0.804	0.196
G20-G26 Extrapyramidal and movement disorders	0.804	0.196
F33.9 Recurrent depressive disorder, unspecified	0.798	0.202
S06 Intracranial injury	0.797	0.203
H43 Disorders of vitreous body	0.797	0.203
F40-F48 Neurotic, stress-related and somatoform disorders	0.795	0.205
R44 Other symptoms and signs involving general sensations and perceptions	0.791	0.209
H10-H13 Disorders of conjunctiva	0.789	0.211
T78 Adverse effects, not elsewhere classified	0.786	0.214
T91.3 Sequelae of injury of spinal cord	0.783	0.217
K52 Other non-infective gastro-enteritis and colitis	0.783	0.217
G83.8 Other specified paralytic syndromes	0.780	0.220
J84.1 Other interstitial pulmonary diseases with fibrosis	0.779	0.221
S01.8 Open wound of other parts of head	0.779	0.221
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.778	0.221
G91 Hydrocephalus	0.777	0.223
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.775	0.225
Y60-Y69 Misadventures to patients during surgical and medical care	0.775	0.225
K10 Other diseases of jaws	0.774	0.226
J95-J99 Other diseases of the respiratory system	0.774	0.226
S02.6 Fracture of mandible	0.774	0.226
G04 Encephalitis, myelitis and encephalomyelitis	0.773	0.227
R54 Senility	0.771	0.229
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.769	0.231
G93.0 Cerebral cysts	0.769	0.231
T79.6 Traumatic ischaemia of muscle	0.764	0.236
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.763	0.237
G82.5 Tetraplegia, unspecified	0.763	0.237
K09 Cysts of oral region, not elsewhere classified	0.763	0.237
R26.2 Difficulty in walking, not elsewhere classified	0.762	0.238
J84.9 Interstitial pulmonary disease, unspecified	0.762	0.238
K03 Other diseases of hard tissues of teeth	0.760	0.240
T94 Sequelae of injuries involving multiple and unspecified body regions	0.760	0.240
G82.4 Spastic tetraplegia	0.758	0.242
K59 Other functional intestinal disorders	0.757	0.243
R26.0 Ataxic gait	0.756	0.244
J01 Acute sinusitis	0.754	0.246
K62 Other diseases of anus and rectum	0.753	0.247
K13.0 Diseases of lips	0.753	0.247
J70 Respiratory conditions due to other external agents	0.753	0.247
G94 Other disorders of brain in diseases classified elsewhere	0.751	0.249
H49.2 Sixth [abducent] nerve palsy	0.750	0.250
G96 Other disorders of central nervous system	0.749	0.251
R68 Other general symptoms and signs	0.749	0.251
S10-S19 Injuries to the neck	0.748	0.252
S05 Injury of eye and orbit	0.746	0.254
H53.1 Subjective visual disturbances	0.744	0.256
G80 Infantile cerebral palsy	0.743	0.257
R25.3 Fasciculation	0.738	0.262
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.737	0.263
R52.0 Acute pain	0.736	0.264
K63.4 Enteroptosis	0.735	0.265
K07 Dentofacial anomalies [including malocclusion]	0.734	0.266
T98 Sequelae of other and unspecified effects of external causes	0.733	0.267
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.732	0.268
S02.8 Fractures of other skull and facial bones	0.732	0.268
W50-W64 Exposure to animate mechanical forces	0.731	0.269
R64 Cachexia	0.728	0.272
S79 Other and unspecified injuries of hip and thigh	0.727	0.273
S20-S29 Injuries to the thorax	0.727	0.273
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.726	0.274
T15-T19 Effects of foreign body entering through natural orifice	0.725	0.275
G25 Other extrapyramidal and movement disorders	0.723	0.277
V80-V89 Other land transport accidents	0.723	0.277
S60-S69 Injuries to the wrist and hand	0.721	0.279
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.720	0.280
K63.8 Other specified diseases of intestine	0.720	0.280
H46-H48 Disorders of optic nerve and visual pathways	0.719	0.281
G01 Meningitis in bacterial diseases classified elsewhere	0.718	0.282
J09-J18 Influenza and pneumonia	0.718	0.282
K02.9 Dental caries, unspecified	0.718	0.282
S50-S59 Injuries to the elbow and forearm	0.718	0.282
J03 Acute tonsillitis	0.718	0.282
R58 Haemorrhage, not elsewhere classified	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
G95.9 Disease of spinal cord, unspecified	0.717	0.283
Q80-Q89 Other congenital malformations	0.717	0.283
H53.6 Night blindness	0.716	0.283
H53.5 Colour vision deficiencies	0.716	0.283
H53.3 Other disorders of binocular vision	0.716	0.283
R56 Convulsions, not elsewhere classified	0.716	0.284
R46 Symptoms and signs involving appearance and behaviour	0.714	0.286
J69.0 Pneumonitis due to food and vomit	0.714	0.286
J67 Hypersensitivity pneumonitis due to organic dust	0.714	0.286
R95-R99 Ill-defined and unknown causes of mortality	0.713	0.286
R45 Symptoms and signs involving emotional state	0.713	0.287
V20-V29 Motorcycle rider injured in transport accident	0.712	0.288
G00 Bacterial meningitis, not elsewhere classified	0.711	0.289
R26.1 Paralytic gait	0.711	0.289
R34 Anuria and oliguria	0.709	0.291
H52 Disorders of refraction and accommodation	0.708	0.292
K63.1 Perforation of intestine (nontraumatic)	0.708	0.292
S02.60 Fracture of mandible (closed)	0.707	0.293
T91.8 Sequelae of other specified injuries of neck and trunk	0.706	0.294
G98 Other disorders of nervous system, not elsewhere classified	0.706	0.294
G92 Toxic encephalopathy	0.706	0.294
K64 Haemorrhoids and perianal venous thrombosis	0.706	0.294
T90.4 Sequelae of injury of eye and orbit	0.705	0.295
K90-K93 Other diseases of the digestive system	0.704	0.296
K62.5 Haemorrhage of anus and rectum	0.704	0.296
K05.3 Chronic periodontitis	0.703	0.297
T33-T35 Frostbite	0.703	0.297
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297
T00-T07 Injuries involving multiple body regions	0.703	0.297
G93.8 Other specified disorders of brain	0.702	0.298
H49.1 Fourth [trochlear] nerve palsy	0.702	0.298
R43 Disturbances of smell and taste	0.701	0.298
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.701	0.299
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.700	0.300
H50.9 Strabismus, unspecified	0.700	0.300
H54 Blindness and low vision	0.699	0.301
H51 Other disorders of binocular movement	0.699	0.301
F99-F99 Unspecified mental disorder	0.697	0.303
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.697	0.303
H43.1 Vitreous haemorrhage	0.697	0.303
Y89 Sequelae of other external causes	0.697	0.303
K12 Stomatitis and related lesions	0.697	0.303
R44.3 Hallucinations, unspecified	0.696	0.304
S02.4 Fracture of malar and maxillary bones	0.696	0.304
K00 Disorders of tooth development and eruption	0.695	0.305
H50.5 Heterophoria	0.694	0.306
T79.7 Traumatic subcutaneous emphysema	0.693	0.307
T90.5 Sequelae of intracranial injury	0.692	0.308
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.692	0.308
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.690	0.310
G30 Alzheimer's disease	0.690	0.310
K51 Ulcerative colitis	0.689	0.311
T20 Burn and corrosion of head and neck	0.689	0.311
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.689	0.311
K56 Paralytic ileus and intestinal obstruction without hernia	0.688	0.312
R55 Syncope and collapse	0.688	0.312
G35-G37 Demyelinating diseases of the central nervous system	0.688	0.312
K65-K67 Diseases of peritoneum	0.687	0.313
G82.2 Paraplegia, unspecified	0.687	0.313
R25.0 Abnormal head movements	0.687	0.313
J82 Pulmonary eosinophilia, not elsewhere classified	0.686	0.314
G83.2 Monoplegia of upper limb	0.686	0.314
T78.4 Allergy, unspecified	0.685	0.315
X20-X29 Contact with venomous animals and plants	0.684	0.316
G70 Myasthenia gravis and other myoneural disorders	0.683	0.317
T68 Hypothermia	0.683	0.317
H43.3 Other vitreous opacities	0.682	0.318
T90.2 Sequelae of fracture of skull and facial bones	0.682	0.318
K63.0 Abscess of intestine	0.682	0.318
X58-X59 Accidental exposure to other and unspecified factors	0.682	0.318
G95.0 Syringomyelia and syringobulbia	0.682	0.318
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.682	0.318
R62 Lack of expected normal physiological development	0.682	0.318
G71 Primary disorders of muscles	0.682	0.318
G93.2 Benign intracranial hypertension	0.681	0.319
T70 Effects of air pressure and water pressure	0.680	0.320
G95.8 Other specified diseases of spinal cord	0.680	0.320
K62.6 Ulcer of anus and rectum	0.680	0.320
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.680	0.320
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.680	0.320
J66 Airway disease due to specific organic dust	0.680	0.320
J63 Pneumoconiosis due to other inorganic dusts	0.680	0.320
J62 Pneumoconiosis due to dust containing silica	0.680	0.320
J65 Pneumoconiosis associated with tuberculosis	0.680	0.320
J64 Unspecified pneumoconiosis	0.680	0.320
J60 Coalworker's pneumoconiosis	0.680	0.320
J84.8 Other specified interstitial pulmonary diseases	0.679	0.321
G09 Sequelae of inflammatory diseases of central nervous system	0.679	0.321
T95 Sequelae of burns, corrosions and frostbite	0.679	0.321
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.679	0.321
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.679	0.321
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.679	0.321
S01.5 Open wound of lip and oral cavity	0.678	0.322
R41.3 Other amnesia	0.678	0.322
F60-F69 Disorders of adult personality and behaviour	0.677	0.322
G83.9 Paralytic syndrome, unspecified	0.677	0.323
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.677	0.323
K04 Diseases of pulp and periapical tissues	0.674	0.326
G11 Hereditary ataxia	0.673	0.327
V10-V19 Pedal cyclist injured in transport accident	0.673	0.327
K13.6 Irritative hyperplasia of oral mucosa	0.672	0.328
G93.7 Reye's syndrome	0.671	0.329
G93.5 Compression of brain	0.671	0.329
X10-X19 Contact with heat and hot substances	0.671	0.329
K05.1 Chronic gingivitis	0.670	0.329
S06.2 Diffuse brain injury	0.669	0.331
S08 Traumatic amputation of part of head	0.668	0.331
S07 Crushing injury of head	0.668	0.331
S04 Injury of cranial nerves	0.668	0.331
S03 Dislocation, sprain and strain of joints and ligaments of head	0.668	0.331
S79.9 Unspecified injury of hip and thigh	0.667	0.333
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.666	0.334
Y35-Y36 Legal intervention and operations of war	0.665	0.335
Y10-Y34 Event of undetermined intent	0.665	0.335
X85-X99 Assault	0.665	0.335
X30-X39 Exposure to forces of nature	0.665	0.335
X00-X09 Exposure to smoke, fire and flames	0.665	0.335
W75-W84 Other accidental threats to breathing	0.665	0.335
W65-W74 Accidental drowning and submersion	0.665	0.335
V98-V99 Other and unspecified transport accidents	0.665	0.335
V95-V97 Air and space transport accidents	0.665	0.335
V90-V94 Water transport accidents	0.665	0.335
V70-V79 Bus occupant injured in transport accident	0.665	0.335
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.665	0.335
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.665	0.335
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.665	0.335
V01-V09 Pedestrian injured in transport accident	0.665	0.335
H11 Other disorders of conjunctiva	0.665	0.335
K09.0 Developmental odontogenic cysts	0.665	0.335
G62 Other polyneuropathies	0.664	0.336
K60.3 Anal fistula	0.663	0.337
F43 Reaction to severe stress, and adjustment disorders	0.662	0.338
K52.8 Other specified non-infective gastro-enteritis and colitis	0.662	0.338
S02.5 Fracture of tooth	0.661	0.339
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.660	0.340
G14 Postpolio syndrome	0.660	0.340
G10 Huntington's disease	0.660	0.340
K63.9 Disease of intestine, unspecified	0.660	0.340
H21 Other disorders of iris and ciliary body	0.660	0.340
R57 Shock, not elsewhere classified	0.658	0.341
G93.4 Encephalopathy, unspecified	0.658	0.342
J04 Acute laryngitis and tracheitis	0.657	0.342
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.657	0.343
F70-F79 Mental retardation	0.657	0.343
T92 Sequelae of injuries of upper limb	0.656	0.343
G91.8 Other hydrocephalus	0.656	0.344
R63 Symptoms and signs concerning food and fluid intake	0.656	0.344
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.655	0.345
K90 Intestinal malabsorption	0.655	0.345
Y00-Y09 Assault	0.654	0.345
R27 Other lack of coordination	0.654	0.346
H49.9 Paralytic strabismus, unspecified	0.654	0.346
H49.8 Other paralytic strabismus	0.654	0.346
H49.4 Progressive external ophthalmoplegia	0.654	0.346
H49.3 Total (external) ophthalmoplegia	0.654	0.346
K60.0 Acute anal fissure	0.653	0.347
G90.2 Horner's syndrome	0.651	0.349
S02.0 Fracture of vault of skull	0.650	0.349
T91.1 Sequelae of fracture of spine	0.650	0.350
G06 Intracranial and intraspinal abscess and granuloma	0.650	0.350
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.650	0.350
G03 Meningitis due to other and unspecified causes	0.650	0.350
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.650	0.350
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.650	0.350
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.650	0.350
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.648	0.352
K04.5 Chronic apical periodontitis	0.648	0.352
X50-X57 Overexertion, travel and privation	0.647	0.353
G95.1 Vascular myelopathies	0.647	0.353
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.647	0.353
G24 Dystonia	0.645	0.355
S76 Injury of muscle and tendon at hip and thigh level	0.645	0.355
F41 Other anxiety disorders	0.645	0.355
F40 Phobic anxiety disorders	0.643	0.357
K60.5 Anorectal fistula	0.643	0.357
Q50-Q56 Congenital malformations of genital organs	0.642	0.357
R30 Pain associated with micturition	0.642	0.358
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.640	0.360
H50.8 Other specified strabismus	0.640	0.360
H50.6 Mechanical strabismus	0.640	0.360
H50.4 Other and unspecified heterotropia	0.640	0.360
H50.3 Intermittent heterotropia	0.640	0.360
H50.2 Vertical strabismus	0.640	0.360
J02.8 Acute pharyngitis due to other specified organisms	0.639	0.361
J02.0 Streptococcal pharyngitis	0.639	0.361
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.638	0.361
K90.0 Coeliac disease	0.638	0.362
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.637	0.363
G82.3 Flaccid tetraplegia	0.637	0.363
G82.1 Spastic paraplegia	0.637	0.363
G82.0 Flaccid paraplegia	0.637	0.363
F39 Unspecified mood [affective] disorder	0.636	0.364
T79.9 Unspecified early complication of trauma	0.636	0.364
T79.8 Other early complications of trauma	0.636	0.364
T79.5 Traumatic anuria	0.636	0.364
T79.4 Traumatic shock	0.636	0.364
T79.2 Traumatic secondary and recurrent haemorrhage	0.636	0.364
T79.1 Fat embolism (traumatic)	0.636	0.364
T79.0 Air embolism (traumatic)	0.636	0.364
S02.80 Fractures of other skull and facial bones (closed)	0.636	0.364
T75 Effects of other external causes	0.636	0.364
T74 Maltreatment syndromes	0.636	0.364
T73 Effects of other deprivation	0.636	0.364
T69 Other effects of reduced temperature	0.636	0.364
T67 Effects of heat and light	0.636	0.364
T71 Asphyxiation	0.636	0.364
T66 Unspecified effects of radiation	0.636	0.364
G90.3 Multisystem degeneration	0.634	0.366
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.634	0.366
K10.8 Other specified diseases of jaws	0.633	0.367
F33.0 Recurrent depressive disorder, current episode mild	0.633	0.367
J20-J22 Other acute lower respiratory infections	0.633	0.367
K55 Vascular disorders of intestine	0.631	0.368
J15 Bacterial pneumonia, not elsewhere classified	0.630	0.370
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.630	0.370
G25.8 Other specified extrapyramidal and movement disorders	0.630	0.370
R36 Urethral discharge	0.629	0.371
K59.0 Constipation	0.628	0.372
V40-V49 Car occupant injured in transport accident	0.628	0.372
K59.3 Megacolon, not elsewhere classified	0.627	0.373
J01.9 Acute sinusitis, unspecified	0.627	0.373
F80-F89 Disorders of psychological development	0.626	0.374
T94.1 Sequelae of injuries, not specified by body region	0.626	0.374
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.626	0.374
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.625	0.374
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.625	0.374
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.625	0.374
T91.9 Sequelae of unspecified injury of neck and trunk	0.625	0.375
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.625	0.375
T91.4 Sequelae of injury of intrathoracic organs	0.625	0.375
T91.2 Sequelae of other fracture of thorax and pelvis	0.625	0.375
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.625	0.375
K03.3 Pathological resorption of teeth	0.625	0.375
R39.2 Extrarenal uraemia	0.625	0.375
R39.0 Extravasation of urine	0.625	0.375
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.624	0.376
F34 Persistent mood [affective] disorders	0.624	0.376
S02.1 Fracture of base of skull	0.623	0.377
J84.0 Alveolar and parietoalveolar conditions	0.623	0.377
S62 Fracture at wrist and hand level	0.622	0.378
T23 Burn and corrosion of wrist and hand	0.622	0.378
G95.2 Cord compression, unspecified	0.622	0.378
G83.5 Locked-in syndrome	0.622	0.378
G83.3 Monoplegia, unspecified	0.622	0.378
G83.1 Monoplegia of lower limb	0.622	0.378
G83.0 Diplegia of upper limbs	0.622	0.378
T78.0 Anaphylactic shock due to adverse food reaction	0.622	0.378
S01.7 Multiple open wounds of head	0.622	0.378
R59 Enlarged lymph nodes	0.621	0.379
S02.9 Fracture of skull and facial bones, part unspecified	0.621	0.379
S02.7 Multiple fractures involving skull and facial bones	0.621	0.379
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.621	0.379
Q20-Q28 Congenital malformations of the circulatory system	0.620	0.380
J98 Other respiratory disorders	0.620	0.380
G61 Inflammatory polyneuropathy	0.618	0.382
H44 Disorders of globe	0.618	0.382
G12.9 Spinal muscular atrophy, unspecified	0.617	0.382
G12.8 Other spinal muscular atrophies and related syndromes	0.617	0.382
G12.1 Other inherited spinal muscular atrophy	0.617	0.382
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.617	0.382
K63.2 Fistula of intestine	0.617	0.383
S02.3 Fracture of orbital floor	0.617	0.383
T93 Sequelae of injuries of lower limb	0.617	0.383
F00-F09 Organic, including symptomatic, mental disorders	0.616	0.384
S06.3 Focal brain injury	0.616	0.384
J86 Pyothorax	0.615	0.385
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.615	0.385
Q35-Q37 Cleft lip and cleft palate	0.615	0.385
Q30-Q34 Congenital malformations of the respiratory system	0.615	0.385
H50.0 Convergent concomitant strabismus	0.614	0.386
J70.1 Chronic and other pulmonary manifestations due to radiation	0.613	0.387
R41.0 Disorientation, unspecified	0.611	0.389
T78.2 Anaphylactic shock, unspecified	0.610	0.390
S01.3 Open wound of ear	0.609	0.391
J81 Pulmonary oedema	0.608	0.391
K40-K46 Hernia	0.608	0.392
R40 Somnolence, stupor and coma	0.606	0.394
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.605	0.394
H11.0 Pterygium	0.605	0.395
Q60-Q64 Congenital malformations of the urinary system	0.605	0.395
G93.6 Cerebral oedema	0.604	0.396
S06.9 Intracranial injury, unspecified	0.603	0.397
H52.2 Astigmatism	0.603	0.397
G72 Other myopathies	0.603	0.397
H47 Other disorders of optic [2nd] nerve and visual pathways	0.602	0.398
H43.9 Disorder of vitreous body, unspecified	0.602	0.398
R52.9 Pain, unspecified	0.601	0.399
J00 Acute nasopharyngitis [common cold]	0.601	0.399
S12 Fracture of neck	0.601	0.399
K02.8 Other dental caries	0.600	0.399
F38 Other mood [affective] disorders	0.600	0.400
F30 Manic episode	0.600	0.400
K62.3 Rectal prolapse	0.600	0.400
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.598	0.402
R52.2 Other chronic pain	0.598	0.402
T90.8 Sequelae of other specified injuries of head	0.598	0.402
T90.3 Sequelae of injury of cranial nerves	0.598	0.402
T90.1 Sequelae of open wound of head	0.598	0.402
T90.0 Sequelae of superficial injury of head	0.598	0.402
J95 Postprocedural respiratory disorders, not elsewhere classified	0.598	0.402
R45.1 Restlessness and agitation	0.597	0.403
R68.8 Other specified general symptoms and signs	0.597	0.403
G96.0 Cerebrospinal fluid leak	0.596	0.404
J17 Pneumonia in diseases classified elsewhere	0.596	0.404
K05.2 Acute periodontitis	0.594	0.406
K05.5 Other periodontal diseases	0.594	0.406
K05.4 Periodontosis	0.594	0.406
K05.0 Acute gingivitis	0.594	0.406
T20.1 Burn of first degree of head and neck	0.594	0.406
D60-D64 Aplastic and other anaemias	0.594	0.406
F25 Schizoaffective disorders	0.592	0.408
Y87.1 Sequelae of assault	0.592	0.408
R25.1 Tremor, unspecified	0.592	0.408
J80 Adult respiratory distress syndrome	0.591	0.409
S64 Injury of nerves at wrist and hand level	0.591	0.409
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.590	0.409
K13.5 Oral submucous fibrosis	0.590	0.409
K13.3 Hairy leukoplakia	0.590	0.409
K13.1 Cheek and lip biting	0.590	0.409
S01.2 Open wound of nose	0.589	0.411
T25 Burn and corrosion of ankle and foot	0.589	0.411
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.589	0.411
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.589	0.411
T21 Burn and corrosion of trunk	0.589	0.411
R61 Hyperhidrosis	0.588	0.412
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.588	0.412
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.588	0.412
S06.4 Epidural haemorrhage	0.587	0.413
S51 Open wound of forearm	0.587	0.413

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations