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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3751845
log Bayes Factor = 2.9765
Chromosome 16   position 3,778,337  (GRCh37) Explore rs3751845 on Ensembl!
Variant rs3751845 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.989 0.011 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
D60-D64 Aplastic and other anaemias
0.968 0.032 0.000
D64 Other anaemias
0.957 0.043 0.000
D64.9 Anaemia, unspecified
0.950 0.050 0.000
E00-E07 Disorders of thyroid gland
0.944 0.056 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.941 0.059 0.000
Chapter IX Diseases of the circulatory system
0.937 0.063 0.000
E70-E90 Metabolic disorders
0.932 0.068 0.000
E03 Other hypothyroidism
0.909 0.091 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.908 0.092 0.000
K90-K93 Other diseases of the digestive system
0.894 0.106 0.000
E03.9 Hypothyroidism, unspecified
0.885 0.115 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.875 0.125 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.875 0.125 0.000
K70-K77 Diseases of liver
0.873 0.127 0.000
Chapter XXI Factors influencing health status and contact with health services
0.869 0.131 0.000
K55-K64 Other diseases of intestines
0.866 0.134 0.000
K31 Other diseases of stomach and duodenum
0.837 0.163 0.000
Chapter V Mental and behavioural disorders
0.831 0.169 0.000
R11 Nausea and vomiting
0.830 0.170 0.000
I30-I52 Other forms of heart disease
0.829 0.171 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.828 0.172 0.000
E78.0 Pure hypercholesterolaemia
0.825 0.175 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.811 0.189 0.000
K92 Other diseases of digestive system
0.801 0.199 0.000
K59 Other functional intestinal disorders
0.792 0.208 0.000
K20 Oesophagitis
0.783 0.217 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.780 0.220 0.000
Chapter VII Diseases of the eye and adnexa
0.777 0.223 0.000
Chapter I Certain infectious and parasitic diseases
0.774 0.226 0.000
D50-D53 Nutritional anaemias
0.770 0.230 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.770 0.230 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.770 0.230 0.000
K29 Gastritis and duodenitis
0.768 0.232 0.000
E10-E14 Diabetes mellitus
0.765 0.235 0.000
K31.8 Other specified diseases of stomach and duodenum
0.764 0.236 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.754 0.246 0.000
K76 Other diseases of liver
0.751 0.249 0.000
K59.0 Constipation
0.740 0.260 0.000
Chapter XX External causes of morbidity and mortality
0.739 0.261 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.734 0.266 0.000
R10 Abdominal and pelvic pain
0.734 0.266 0.000
Chapter VIII Diseases of the ear and mastoid process
0.731 0.268 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.731 0.269 0.000
K22 Other diseases of oesophagus
0.730 0.269 0.000
Chapter X Diseases of the respiratory system
0.730 0.270 0.000
E65-E68 Obesity and other hyperalimentation
0.724 0.276 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.722 0.278 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
K40-K46 Hernia
0.714 0.286 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.713 0.286 0.000
K35-K38 Diseases of appendix
0.711 0.289 0.000
Z13 Special screening examination for other diseases and disorders
0.710 0.290 0.000
E50-E64 Other nutritional deficiencies
0.709 0.291 0.000
E40-E46 Malnutrition
0.709 0.291 0.000
E20-E35 Disorders of other endocrine glands
0.709 0.291 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.709 0.291 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.707 0.293 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.705 0.295 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.703 0.297 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.703 0.297 0.000
K30 Dyspepsia
0.703 0.297 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.702 0.298 0.000
K74 Fibrosis and cirrhosis of liver
0.702 0.298 0.000
K25 Gastric ulcer
0.702 0.298 0.000
R18 Ascites
0.701 0.299 0.000
E86 Volume depletion
0.699 0.301 0.000
Chapter II Neoplasms
0.696 0.304 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.694 0.306 0.000
D61 Other aplastic anaemias
0.694 0.306 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.694 0.306 0.000
D62 Acute posthaemorrhagic anaemia
0.694 0.306 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.692 0.308 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.688 0.312 0.000
D64.8 Other specified anaemias
0.686 0.313 0.000
D64.4 Congenital dyserythropoietic anaemia
0.686 0.313 0.000
D64.3 Other sideroblastic anaemias
0.686 0.313 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.686 0.313 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.686 0.313 0.000
D64.0 Hereditary sideroblastic anaemia
0.686 0.313 0.000
I44 Atrioventricular and left bundle-branch block
0.683 0.316 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.683 0.317 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.680 0.320 0.000
I60-I69 Cerebrovascular diseases
0.679 0.320 0.000
K92.1 Melaena
0.679 0.321 0.000
E07 Other disorders of thyroid
0.676 0.323 0.000
E06 Thyroiditis
0.676 0.323 0.000
E04 Other non-toxic goitre
0.676 0.323 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.676 0.323 0.000
E00 Congenital iodine-deficiency syndrome
0.676 0.323 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.676 0.323 0.000
R15 Faecal incontinence
0.676 0.324 0.000
K28 Gastrojejunal ulcer
0.675 0.325 0.000
K27 Peptic ulcer, site unspecified
0.675 0.325 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.675 0.325 0.000
Chapter XIV Diseases of the genitourinary system
0.674 0.326 0.000
I84 Haemorrhoids
0.673 0.327 0.000
K65-K67 Diseases of peritoneum
0.672 0.328 0.000
I05-I09 Chronic rheumatic heart diseases
0.672 0.328 0.000
I00-I02 Acute rheumatic fever
0.672 0.328 0.000
E78.5 Hyperlipidaemia, unspecified
0.670 0.330 0.000
K26 Duodenal ulcer
0.669 0.331 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.668 0.332 0.000
E88 Other metabolic disorders
0.668 0.332 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E83 Disorders of mineral metabolism
0.668 0.332 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E74 Other disorders of carbohydrate metabolism
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.667 0.333 0.000
I45 Other conduction disorders
0.666 0.334 0.000
R07 Pain in throat and chest
0.665 0.335 0.000
I83 Varicose veins of lower extremities
0.662 0.338 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.659 0.341 0.000
K29.7 Gastritis, unspecified
0.657 0.343 0.000
K60 Fissure and fistula of anal and rectal regions
0.657 0.343 0.000
R10.4 Other and unspecified abdominal pain
0.655 0.345 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.652 0.348 0.000
E03.8 Other specified hypothyroidism
0.652 0.348 0.000
E03.5 Myxoedema coma
0.652 0.348 0.000
E03.4 Atrophy of thyroid (acquired)
0.652 0.348 0.000
E03.3 Postinfectious hypothyroidism
0.652 0.348 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.652 0.348 0.000
E03.1 Congenital hypothyroidism without goitre
0.652 0.348 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.652 0.348 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.651 0.349 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.651 0.349 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.651 0.349 0.000
R47-R49 Symptoms and signs involving speech and voice
0.651 0.349 0.000
I47 Paroxysmal tachycardia
0.647 0.353 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.641 0.359 0.000
K90 Intestinal malabsorption
0.641 0.359 0.000
K63 Other diseases of intestine
0.640 0.360 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.639 0.361 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.638 0.362 0.000
Z12 Special screening examination for neoplasms
0.636 0.363 0.000
K50-K52 Noninfective enteritis and colitis
0.636 0.364 0.000
I20-I25 Ischaemic heart diseases
0.632 0.368 0.000
K62 Other diseases of anus and rectum
0.628 0.372 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.627 0.373 0.000
R17 Unspecified jaundice
0.627 0.373 0.000
R14 Flatulence and related conditions
0.627 0.373 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.627 0.373 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.627 0.373 0.000
E78.8 Other disorders of lipoprotein metabolism
0.627 0.373 0.000
E78.6 Lipoprotein deficiency
0.627 0.373 0.000
E78.4 Other hyperlipidaemia
0.627 0.373 0.000
E78.3 Hyperchylomicronaemia
0.627 0.373 0.000
E78.2 Mixed hyperlipidaemia
0.627 0.373 0.000
E78.1 Pure hyperglyceridaemia
0.627 0.373 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.627 0.373 0.000
K77 Liver disorders in diseases classified elsewhere
0.626 0.374 0.000
K75 Other inflammatory liver diseases
0.626 0.374 0.000
K73 Chronic hepatitis, not elsewhere classified
0.626 0.374 0.000
K72 Hepatic failure, not elsewhere classified
0.626 0.374 0.000
K71 Toxic liver disease
0.626 0.374 0.000
K70 Alcoholic liver disease
0.626 0.374 0.000
J09-J18 Influenza and pneumonia
0.625 0.375 0.000
Chapter VI Diseases of the nervous system
0.624 0.376 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.623 0.377 0.000
R10.1 Pain localised to upper abdomen
0.623 0.377 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.623 0.377 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.621 0.379 0.000
K61 Abscess of anal and rectal regions
0.621 0.379 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.621 0.379 0.000
K55 Vascular disorders of intestine
0.621 0.379 0.000
D50 Iron deficiency anaemia
0.618 0.382 0.000
K76.6 Portal hypertension
0.618 0.382 0.000
I50 Heart failure
0.618 0.382 0.000
I35 Nonrheumatic aortic valve disorders
0.617 0.383 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.617 0.383 0.000
I10-I15 Hypertensive diseases
0.616 0.384 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.614 0.386 0.000
I78 Diseases of capillaries
0.614 0.386 0.000
E11 Non-insulin-dependent diabetes mellitus
0.612 0.388 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.611 0.389 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.611 0.389 0.000
H30-H36 Disorders of choroid and retina
0.609 0.391 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.608 0.392 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.607 0.392 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.606 0.394 0.000
I73 Other peripheral vascular diseases
0.602 0.398 0.000
F30-F39 Mood [affective] disorders
0.602 0.398 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.602 0.398 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.601 0.398 0.000
K13 Other diseases of lip and oral mucosa
0.600 0.400 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.600 0.400 0.000
K31.6 Fistula of stomach and duodenum
0.600 0.400 0.000
K31.5 Obstruction of duodenum
0.600 0.400 0.000
K31.4 Gastric diverticulum
0.600 0.400 0.000
K31.3 Pylorospasm, not elsewhere classified
0.600 0.400 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.600 0.400 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.600 0.400 0.000
K31.0 Acute dilatation of stomach
0.600 0.400 0.000
A00-A09 Intestinal infectious diseases
0.598 0.402 0.000
F99-F99 Unspecified mental disorder
0.596 0.404 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.596 0.404 0.000
F80-F89 Disorders of psychological development
0.596 0.404 0.000
F70-F79 Mental retardation
0.596 0.404 0.000
F60-F69 Disorders of adult personality and behaviour
0.596 0.404 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.596 0.404 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.596 0.404 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.596 0.404 0.000
K76.8 Other specified diseases of liver
0.594 0.405 0.000
I52 Other heart disorders in diseases classified elsewhere
0.594 0.406 0.000
I49 Other cardiac arrhythmias
0.594 0.406 0.000
I48 Atrial fibrillation and flutter
0.594 0.406 0.000
I46 Cardiac arrest
0.594 0.406 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.594 0.406 0.000
I42 Cardiomyopathy
0.594 0.406 0.000
I41 Myocarditis in diseases classified elsewhere
0.594 0.406 0.000
I40 Acute myocarditis
0.594 0.406 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.594 0.406 0.000
I37 Pulmonary valve disorders
0.594 0.406 0.000
I36 Nonrheumatic tricuspid valve disorders
0.594 0.406 0.000
I33 Acute and subacute endocarditis
0.594 0.406 0.000
I32 Pericarditis in diseases classified elsewhere
0.594 0.406 0.000
I31 Other diseases of pericardium
0.594 0.406 0.000
I30 Acute pericarditis
0.594 0.406 0.000
I38 Endocarditis, valve unspecified
0.594 0.406 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.594 0.406 0.000
Z10 Routine general health check-up of defined subpopulation
0.594 0.406 0.000
Z04 Examination and observation for other reasons
0.594 0.406 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.594 0.406 0.000
K31.7 Polyp of stomach and duodenum
0.593 0.407 0.000
K57 Diverticular disease of intestine
0.592 0.408 0.000
B95-B98 Bacterial, viral and other infectious agents
0.592 0.408 0.000
H40-H42 Glaucoma
0.588 0.412 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.585 0.415 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.585 0.415 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.583 0.416 0.000
R12 Heartburn
0.583 0.417 0.000
M70-M79 Other soft tissue disorders
0.582 0.418 0.000
K22.1 Ulcer of oesophagus
0.582 0.418 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.581 0.419 0.000
I88 Nonspecific lymphadenitis
0.581 0.419 0.000
I87 Other disorders of veins
0.581 0.419 0.000
I86 Varicose veins of other sites
0.581 0.419 0.000
I85 Oesophageal varices
0.581 0.419 0.000
I82 Other venous embolism and thrombosis
0.581 0.419 0.000
I81 Portal vein thrombosis
0.581 0.419 0.000
I44.7 Left bundle-branch block, unspecified
0.579 0.421 0.000
I51 Complications and ill-defined descriptions of heart disease
0.579 0.421 0.000
K74.6 Other and unspecified cirrhosis of liver
0.579 0.421 0.000
K21 Gastro-oesophageal reflux disease
0.578 0.422 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.577 0.423 0.000
I80 Phlebitis and thrombophlebitis
0.577 0.423 0.000
O80-O84 Delivery
0.575 0.425 0.000
K92.9 Disease of digestive system, unspecified
0.574 0.425 0.000
K92.8 Other specified diseases of digestive system
0.574 0.425 0.000
K29.5 Chronic gastritis, unspecified
0.574 0.426 0.000
Z02 Examination and encounter for administrative purposes
0.572 0.428 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.571 0.429 0.000
K92.0 Haematemesis
0.571 0.429 0.000
K02 Dental caries
0.568 0.432 0.000
K59.9 Functional intestinal disorder, unspecified
0.568 0.432 0.000
K59.8 Other specified functional intestinal disorders
0.568 0.432 0.000
K59.4 Anal spasm
0.568 0.432 0.000
K59.3 Megacolon, not elsewhere classified
0.568 0.432 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.568 0.432 0.000
K59.1 Functional diarrhoea
0.568 0.432 0.000
R07.3 Other chest pain
0.568 0.432 0.000
B25-B34 Other viral diseases
0.566 0.434 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.565 0.434 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.565 0.435 0.000
E87.5 Hyperkalaemia
0.562 0.438 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.561 0.439 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.560 0.440 0.000
R50-R69 General symptoms and signs
0.560 0.440 0.000
I34 Nonrheumatic mitral valve disorders
0.559 0.440 0.000
L50-L54 Urticaria and erythema
0.559 0.441 0.000
L40-L45 Papulosquamous disorders
0.559 0.441 0.000
L20-L30 Dermatitis and eczema
0.559 0.441 0.000
L10-L14 Bullous disorders
0.559 0.441 0.000
H55-H59 Other disorders of eye and adnexa
0.557 0.442 0.000
H53-H54 Visual disturbances and blindness
0.557 0.442 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.557 0.442 0.000
H43-H45 Disorders of vitreous body and globe
0.557 0.442 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.557 0.442 0.000
H10-H13 Disorders of conjunctiva
0.557 0.442 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.555 0.445 0.000
B99-B99 Other infectious diseases
0.555 0.445 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.555 0.445 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.555 0.445 0.000
B65-B83 Helminthiases
0.555 0.445 0.000
B50-B64 Protozoal diseases
0.555 0.445 0.000
B35-B49 Mycoses
0.555 0.445 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.555 0.445 0.000
B15-B19 Viral hepatitis
0.555 0.445 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.555 0.445 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.555 0.445 0.000
A80-A89 Viral infections of the central nervous system
0.555 0.445 0.000
A75-A79 Rickettsioses
0.555 0.445 0.000
A70-A74 Other diseases caused by chlamydiae
0.555 0.445 0.000
A65-A69 Other spirochaetal diseases
0.555 0.445 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.555 0.445 0.000
A20-A28 Certain zoonotic bacterial diseases
0.555 0.445 0.000
A15-A19 Tuberculosis
0.555 0.445 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.553 0.447 0.000
R07.2 Precordial pain
0.552 0.447 0.000
M50-M54 Other dorsopathies
0.552 0.447 0.000
D53 Other nutritional anaemias
0.552 0.448 0.000
D52 Folate deficiency anaemia
0.552 0.448 0.000
D51 Vitamin B12 deficiency anaemia
0.552 0.448 0.000
K14 Diseases of tongue
0.552 0.448 0.000
K12 Stomatitis and related lesions
0.552 0.448 0.000
K11 Diseases of salivary glands
0.552 0.448 0.000
K10 Other diseases of jaws
0.552 0.448 0.000
K09 Cysts of oral region, not elsewhere classified
0.552 0.448 0.000
K07 Dentofacial anomalies [including malocclusion]
0.552 0.448 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.552 0.448 0.000
K05 Gingivitis and periodontal diseases
0.552 0.448 0.000
K04 Diseases of pulp and periapical tissues
0.552 0.448 0.000
K03 Other diseases of hard tissues of teeth
0.552 0.448 0.000
K01 Embedded and impacted teeth
0.552 0.448 0.000
K00 Disorders of tooth development and eruption
0.552 0.448 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.552 0.448 0.000
I77 Other disorders of arteries and arterioles
0.552 0.448 0.000
I74 Arterial embolism and thrombosis
0.552 0.448 0.000
I72 Other aneurysm
0.552 0.448 0.000
I71 Aortic aneurysm and dissection
0.552 0.448 0.000
I70 Atherosclerosis
0.552 0.448 0.000
K29.9 Gastroduodenitis, unspecified
0.551 0.449 0.000
K29.4 Chronic atrophic gastritis
0.551 0.449 0.000
K29.3 Chronic superficial gastritis
0.551 0.449 0.000
K29.2 Alcoholic gastritis
0.551 0.449 0.000
K29.1 Other acute gastritis
0.551 0.449 0.000
K29.0 Acute haemorrhagic gastritis
0.551 0.449 0.000
E14 Unspecified diabetes mellitus
0.550 0.449 0.000
J18 Pneumonia, organism unspecified
0.550 0.450 0.000
K44 Diaphragmatic hernia
0.550 0.450 0.000
I45.1 Other and unspecified right bundle-branch block
0.550 0.450 0.000
K29.6 Other gastritis
0.550 0.450 0.000
K08 Other disorders of teeth and supporting structures
0.550 0.450 0.000
E13 Other specified diabetes mellitus
0.548 0.452 0.000
E12 Malnutrition-related diabetes mellitus
0.548 0.452 0.000
K40 Inguinal hernia
0.548 0.452 0.000
R21 Rash and other nonspecific skin eruption
0.547 0.453 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.546 0.453 0.000
O60-O75 Complications of labour and delivery
0.545 0.455 0.000
I84.6 Residual haemorrhoidal skin tags
0.543 0.457 0.000
I84.8 Unspecified haemorrhoids with other complications
0.541 0.459 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.541 0.459 0.000
O85-O92 Complications predominantly related to the puerperium
0.541 0.459 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.541 0.459 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.541 0.459 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.541 0.459 0.000
O00-O08 Pregnancy with abortive outcome
0.541 0.459 0.000
C60-C63 Malignant neoplasms of male genital organs
0.540 0.460 0.000
N60-N64 Disorders of breast
0.540 0.460 0.000
H90-H95 Other disorders of ear
0.540 0.460 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.540 0.460 0.000
K76.9 Liver disease, unspecified
0.538 0.462 0.000
K76.7 Hepatorenal syndrome
0.538 0.462 0.000
K76.5 Hepatic veno-occlusive disease
0.538 0.462 0.000
K76.4 Peliosis hepatis
0.538 0.462 0.000
K76.3 Infarction of liver
0.538 0.462 0.000
K76.2 Central haemorrhagic necrosis of liver
0.538 0.462 0.000
K76.1 Chronic passive congestion of liver
0.538 0.462 0.000
M15-M19 Arthrosis
0.538 0.462 0.000
E10 Insulin-dependent diabetes mellitus
0.535 0.465 0.000
C64-C68 Malignant neoplasms of urinary tract
0.535 0.465 0.000
E66 Obesity
0.534 0.466 0.000
R07.4 Chest pain, unspecified
0.533 0.467 0.000
Z03.8 Observation for other suspected diseases and conditions
0.531 0.469 0.000
L60-L75 Disorders of skin appendages
0.530 0.470 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.530 0.470 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.530 0.470 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.530 0.470 0.000
Y35-Y36 Legal intervention and operations of war
0.530 0.470 0.000
Y10-Y34 Event of undetermined intent
0.530 0.470 0.000
Y00-Y09 Assault
0.530 0.470 0.000
X85-X99 Assault
0.530 0.470 0.000
X60-X84 Intentional self-harm
0.530 0.470 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.530 0.470 0.000
X50-X57 Overexertion, travel and privation
0.530 0.470 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.530 0.470 0.000
X30-X39 Exposure to forces of nature
0.530 0.470 0.000
X20-X29 Contact with venomous animals and plants
0.530 0.470 0.000
X10-X19 Contact with heat and hot substances
0.530 0.470 0.000
X00-X09 Exposure to smoke, fire and flames
0.530 0.470 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.530 0.470 0.000
W75-W84 Other accidental threats to breathing
0.530 0.470 0.000
W65-W74 Accidental drowning and submersion
0.530 0.470 0.000
W50-W64 Exposure to animate mechanical forces
0.530 0.470 0.000
W20-W49 Exposure to inanimate mechanical forces
0.530 0.470 0.000
V98-V99 Other and unspecified transport accidents
0.530 0.470 0.000
V95-V97 Air and space transport accidents
0.530 0.470 0.000
V90-V94 Water transport accidents
0.530 0.470 0.000
V80-V89 Other land transport accidents
0.530 0.470 0.000
V70-V79 Bus occupant injured in transport accident
0.530 0.470 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.530 0.470 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.530 0.470 0.000
V40-V49 Car occupant injured in transport accident
0.530 0.470 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.530 0.470 0.000
V20-V29 Motorcycle rider injured in transport accident
0.530 0.470 0.000
V10-V19 Pedal cyclist injured in transport accident
0.530 0.470 0.000
V01-V09 Pedestrian injured in transport accident
0.530 0.470 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.530 0.470 0.000
J30-J39 Other diseases of upper respiratory tract
0.530 0.470 0.000
F10.1 Harmful use
0.530 0.470 0.000
S80-S89 Injuries to the knee and lower leg
0.529 0.471 0.000
N25-N29 Other disorders of kidney and ureter
0.529 0.471 0.000
E87.6 Hypokalaemia
0.529 0.471 0.000
J95-J99 Other diseases of the respiratory system
0.528 0.472 0.000
W00-W19 Falls
0.528 0.472 0.000
D00-D09 In situ neoplasms
0.527 0.472 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.526 0.474 0.000
M91-M94 Chondropathies
0.526 0.474 0.000
M86-M90 Other osteopathies
0.526 0.474 0.000
M65-M68 Disorders of synovium and tendon
0.526 0.474 0.000
M60-M63 Disorders of muscles
0.526 0.474 0.000
M40-M43 Deforming dorsopathies
0.526 0.474 0.000
M00-M03 Infectious arthropathies
0.526 0.474 0.000
R10.2 Pelvic and perineal pain
0.526 0.474 0.000
R10.0 Acute abdomen
0.526 0.474 0.000
H80-H83 Diseases of inner ear
0.524 0.475 0.000
H65-H75 Diseases of middle ear and mastoid
0.524 0.475 0.000
H60-H62 Diseases of external ear
0.524 0.475 0.000
M80-M85 Disorders of bone density and structure
0.524 0.475 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.524 0.476 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.524 0.476 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.524 0.476 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.524 0.476 0.000
Z13.9 Special screening examination, unspecified
0.524 0.476 0.000
K22.9 Disease of oesophagus, unspecified
0.524 0.476 0.000
K22.8 Other specified diseases of oesophagus
0.524 0.476 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.524 0.476 0.000
K22.5 Diverticulum of oesophagus, acquired
0.524 0.476 0.000
K22.4 Dyskinesia of oesophagus
0.524 0.476 0.000
K22.3 Perforation of oesophagus
0.524 0.476 0.000
K22.2 Oesophageal obstruction
0.524 0.476 0.000
K22.0 Achalasia of cardia
0.524 0.476 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.524 0.476 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.524 0.476 0.000
J60-J70 Lung diseases due to external agents
0.524 0.476 0.000
J00-J06 Acute upper respiratory infections
0.524 0.476 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.523 0.477 0.000
S60-S69 Injuries to the wrist and hand
0.523 0.477 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.522 0.478 0.000
K22.7 Barrett's oesophagus
0.521 0.479 0.000
E67 Other hyperalimentation
0.519 0.481 0.000
E68 Sequelae of hyperalimentation
0.519 0.481 0.000
E65 Localised adiposity
0.519 0.481 0.000
I84.9 Unspecified haemorrhoids without complication
0.518 0.482 0.000
A30-A49 Other bacterial diseases
0.518 0.482 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.517 0.482 0.000
R01 Cardiac murmurs and other cardiac sounds
0.517 0.482 0.000
R02 Gangrene, not elsewhere classified
0.517 0.482 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.517 0.482 0.000
E87.7 Fluid overload
0.517 0.482 0.000
E87.4 Mixed disorder of acid-base balance
0.517 0.482 0.000
E87.3 Alkalosis
0.517 0.482 0.000
E87.2 Acidosis
0.517 0.482 0.000
E87.0 Hyperosmolality and hypernatraemia
0.517 0.482 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.517 0.483 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.517 0.483 0.000
F10.2 Dependence syndrome
0.516 0.483 0.000
I47.1 Supraventricular tachycardia
0.516 0.483 0.000
R20 Disturbances of skin sensation
0.516 0.484 0.000
P90-P96 Other disorders originating in the perinatal period
0.513 0.486 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.513 0.486 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.513 0.486 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.513 0.486 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.513 0.486 0.000
P35-P39 Infections specific to the perinatal period
0.513 0.486 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.513 0.486 0.000
P10-P15 Birth trauma
0.513 0.486 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.513 0.486 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.513 0.486 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.513 0.486 0.000
Q80-Q89 Other congenital malformations
0.513 0.486 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.513 0.486 0.000
Q60-Q64 Congenital malformations of the urinary system
0.513 0.486 0.000
Q50-Q56 Congenital malformations of genital organs
0.513 0.486 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.513 0.486 0.000
Q35-Q37 Cleft lip and cleft palate
0.513 0.486 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.513 0.486 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.513 0.486 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.513 0.486 0.000
Q00-Q07 Congenital malformations of the nervous system
0.513 0.486 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.513 0.486 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.513 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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