TreeWAS – Variant ID: rs7192981

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter II Neoplasms	1.000	0.000
E66.9 Obesity, unspecified	1.000	0.000
E65-E68 Obesity and other hyperalimentation	1.000	0.000
E66 Obesity	0.999	0.001
C15-C26 Malignant neoplasms of digestive organs	0.997	0.003
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.990	0.010
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.978	0.022
C18 Malignant neoplasm of colon	0.975	0.025
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.975	0.025
E70-E90 Metabolic disorders	0.973	0.027
Chapter VIII Diseases of the ear and mastoid process	0.971	0.029
D37-D48 Neoplasms of uncertain or unknown behaviour	0.966	0.034
M70-M79 Other soft tissue disorders	0.964	0.036
C18.7 Sigmoid colon	0.961	0.039
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.958	0.042
D69 Purpura and other haemorrhagic conditions	0.949	0.051
H65-H75 Diseases of middle ear and mastoid	0.949	0.051
S20-S29 Injuries to the thorax	0.946	0.054
E87 Other disorders of fluid, electrolyte and acid-base balance	0.940	0.060
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.940	0.060
S90-S99 Injuries to the ankle and foot	0.932	0.068
C20 Malignant neoplasm of rectum	0.932	0.068
M72 Fibroblastic disorders	0.930	0.070
T90 Sequelae of injuries of head	0.930	0.070
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.928	0.072
T93 Sequelae of injuries of lower limb	0.924	0.076
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.915	0.085
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.911	0.088
D69.6 Thrombocytopenia, unspecified	0.909	0.091
Chapter XII Diseases of the skin and subcutaneous tissue	0.899	0.101
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.898	0.102
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.895	0.105
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.894	0.106
E20-E35 Disorders of other endocrine glands	0.889	0.111
L00-L08 Infections of the skin and subcutaneous tissue	0.886	0.114
L02 Cutaneous abscess, furuncle and carbuncle	0.884	0.116
E78.5 Hyperlipidaemia, unspecified	0.883	0.117
M75 Shoulder lesions	0.881	0.119
H60-H62 Diseases of external ear	0.880	0.120
D00-D09 In situ neoplasms	0.879	0.121
H74 Other disorders of middle ear and mastoid	0.877	0.123
D50-D53 Nutritional anaemias	0.877	0.123
T91 Sequelae of injuries of neck and trunk	0.874	0.126
T79-T79 Certain early complications of trauma	0.873	0.127
T93.2 Sequelae of other fractures of lower limb	0.872	0.128
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.869	0.131
Chapter V Mental and behavioural disorders	0.867	0.133
T92 Sequelae of injuries of upper limb	0.864	0.136
E87.2 Acidosis	0.860	0.140
E50-E64 Other nutritional deficiencies	0.857	0.142
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.857	0.143
S22 Fracture of rib(s), sternum and thoracic spine	0.856	0.144
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.855	0.145
E00-E07 Disorders of thyroid gland	0.854	0.146
H71 Cholesteatoma of middle ear	0.854	0.146
E87.1 Hypo-osmolality and hyponatraemia	0.852	0.148
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.852	0.148
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.852	0.148
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.850	0.150
C18.0 Caecum	0.848	0.152
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.847	0.153
C16 Malignant neoplasm of stomach	0.844	0.156
C25 Malignant neoplasm of pancreas	0.837	0.163
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.837	0.163
S91 Open wound of ankle and foot	0.835	0.165
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.835	0.165
M75.0 Adhesive capsulitis of shoulder	0.834	0.166
D68 Other coagulation defects	0.833	0.167
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.832	0.168
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.826	0.174
H73 Other disorders of tympanic membrane	0.824	0.176
M91-M94 Chondropathies	0.819	0.181
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.817	0.183
D80-D89 Certain disorders involving the immune mechanism	0.816	0.184
H61 Other disorders of external ear	0.814	0.186
S10-S19 Injuries to the neck	0.814	0.186
S00-S09 Injuries to the head	0.809	0.191
M45-M49 Spondylopathies	0.805	0.195
T90.2 Sequelae of fracture of skull and facial bones	0.803	0.197
H74.3 Other acquired abnormalities of ear ossicles	0.802	0.198
M75.1 Rotator cuff syndrome	0.802	0.198
C83 Diffuse non-Hodgkin's lymphoma	0.799	0.201
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.799	0.201
C51-C58 Malignant neoplasms of female genital organs	0.798	0.202
S21 Open wound of thorax	0.797	0.203
E87.0 Hyperosmolality and hypernatraemia	0.795	0.205
D69.5 Secondary thrombocytopenia	0.795	0.205
D46 Myelodysplastic syndromes	0.791	0.209
D41.4 Bladder	0.790	0.210
C90 Multiple myeloma and malignant plasma cell neoplasms	0.789	0.211
T90.9 Sequelae of unspecified injury of head	0.788	0.212
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.786	0.214
E04 Other non-toxic goitre	0.785	0.215
E89.0 Postprocedural hypothyroidism	0.784	0.216
T79 Certain early complications of trauma, not elsewhere classified	0.783	0.217
F00-F09 Organic, including symptomatic, mental disorders	0.782	0.218
E23 Hypofunction and other disorders of pituitary gland	0.780	0.220
C92 Myeloid leukaemia	0.771	0.229
M65-M68 Disorders of synovium and tendon	0.771	0.229
H69 Other disorders of Eustachian tube	0.771	0.229
E66.0 Obesity due to excess calories	0.770	0.230
M00-M03 Infectious arthropathies	0.766	0.234
D50 Iron deficiency anaemia	0.763	0.237
T88 Other complications of surgical and medical care, not elsewhere classified	0.763	0.237
T98 Sequelae of other and unspecified effects of external causes	0.762	0.238
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.761	0.239
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.759	0.241
H61.8 Other specified disorders of external ear	0.757	0.243
H70 Mastoiditis and related conditions	0.755	0.245
D45 Polycythaemia vera	0.754	0.246
S70-S79 Injuries to the hip and thigh	0.753	0.247
E04.1 Non-toxic single thyroid nodule	0.752	0.248
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.752	0.248
D48.1 Connective and other soft tissue	0.751	0.249
E87.6 Hypokalaemia	0.750	0.250
T91.8 Sequelae of other specified injuries of neck and trunk	0.749	0.251
M60-M63 Disorders of muscles	0.748	0.251
T20-T25 Burns and corrosions of external body surface, specified by site	0.747	0.253
D66 Hereditary factor VIII deficiency	0.744	0.256
E80 Disorders of porphyrin and bilirubin metabolism	0.744	0.256
S91.3 Open wound of other parts of foot	0.744	0.256
M70 Soft tissue disorders related to use, overuse and pressure	0.742	0.257
C73 Malignant neoplasm of thyroid gland	0.742	0.258
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.741	0.259
S27 Injury of other and unspecified intrathoracic organs	0.740	0.260
T86 Failure and rejection of transplanted organs and tissues	0.740	0.260
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.739	0.261
Chapter I Certain infectious and parasitic diseases	0.738	0.262
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.737	0.263
C23 Malignant neoplasm of gallbladder	0.736	0.264
D69.3 Idiopathic thrombocytopenic purpura	0.735	0.265
H73.8 Other specified disorders of tympanic membrane	0.734	0.266
D04 Carcinoma in situ of skin	0.734	0.266
T90.8 Sequelae of other specified injuries of head	0.732	0.268
M76 Enthesopathies of lower limb, excluding foot	0.731	0.269
C32 Malignant neoplasm of larynx	0.730	0.270
T87 Complications peculiar to reattachment and amputation	0.722	0.278
S22.4 Multiple fractures of ribs	0.721	0.279
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.721	0.279
D68.5 Primary Thrombophilia	0.718	0.282
S90 Superficial injury of ankle and foot	0.718	0.282
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.717	0.283
D70-D77 Other diseases of blood and blood-forming organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
E67 Other hyperalimentation	0.717	0.283
E68 Sequelae of hyperalimentation	0.717	0.283
E65 Localised adiposity	0.717	0.283
C18.9 Colon, unspecified	0.717	0.283
E66.2 Extreme obesity with alveolar hypoventilation	0.716	0.283
E66.1 Drug-induced obesity	0.716	0.283
E40-E46 Malnutrition	0.716	0.284
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.715	0.285
E24 Cushing's syndrome	0.715	0.285
E78.1 Pure hyperglyceridaemia	0.715	0.285
C21 Malignant neoplasm of anus and anal canal	0.715	0.285
C17 Malignant neoplasm of small intestine	0.715	0.285
S40-S49 Injuries to the shoulder and upper arm	0.715	0.285
D09 Carcinoma in situ of other and unspecified sites	0.714	0.286
T95 Sequelae of burns, corrosions and frostbite	0.714	0.286
T94 Sequelae of injuries involving multiple and unspecified body regions	0.714	0.286
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.714	0.286
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.714	0.286
T92.2 Sequelae of fracture at wrist and hand level	0.712	0.288
Chapter XXII Codes for special purposes	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.288
S80-S89 Injuries to the knee and lower leg	0.711	0.289
S99 Other and unspecified injuries of ankle and foot	0.710	0.289
M86-M90 Other osteopathies	0.710	0.290
C16.9 Stomach, unspecified	0.710	0.290
H66 Suppurative and unspecified otitis media	0.710	0.290
D51 Vitamin B12 deficiency anaemia	0.710	0.290
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.707	0.293
S92 Fracture of foot, except ankle	0.705	0.295
E55 Vitamin D deficiency	0.704	0.296
C54 Malignant neoplasm of corpus uteri	0.704	0.296
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.703	0.296
T58 Toxic effect of carbon monoxide	0.703	0.297
C18.1 Appendix	0.703	0.297
D50.9 Iron deficiency anaemia, unspecified	0.701	0.299
C25.9 Pancreas, unspecified	0.700	0.300
C82.1 Mixed small cleaved and large cell, follicular	0.700	0.300
C71 Malignant neoplasm of brain	0.700	0.300
C69 Malignant neoplasm of eye and adnexa	0.699	0.301
C18.8 Overlapping lesion of colon	0.699	0.301
D67 Hereditary factor IX deficiency	0.699	0.301
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.699	0.301
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.698	0.302
E85 Amyloidosis	0.698	0.302
E84 Cystic fibrosis	0.698	0.302
E79 Disorders of purine and pyrimidine metabolism	0.698	0.302
E77 Disorders of glycoprotein metabolism	0.698	0.302
E76 Disorders of glycosaminoglycan metabolism	0.698	0.302
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.698	0.302
E74 Other disorders of carbohydrate metabolism	0.698	0.302
E73 Lactose intolerance	0.698	0.302
E72 Other disorders of amino-acid metabolism	0.698	0.302
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.698	0.302
E70 Disorders of aromatic amino-acid metabolism	0.698	0.302
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.698	0.302
Chapter XXI Factors influencing health status and contact with health services	0.698	0.302
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.694	0.306
T90.5 Sequelae of intracranial injury	0.693	0.307
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.693	0.307
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.693	0.307
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.693	0.307
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.692	0.308
S29 Other and unspecified injuries of thorax	0.691	0.309
M73 Soft tissue disorders in diseases classified elsewhere	0.691	0.309
D55-D59 Haemolytic anaemias	0.691	0.309
M80-M85 Disorders of bone density and structure	0.691	0.309
T92.1 Sequelae of fracture of arm	0.691	0.309
S21.1 Open wound of front wall of thorax	0.690	0.310
Q20-Q28 Congenital malformations of the circulatory system	0.690	0.310
F30-F39 Mood [affective] disorders	0.689	0.311
E05 Thyrotoxicosis [hyperthyroidism]	0.689	0.311
M79 Other soft tissue disorders, not elsewhere classified	0.689	0.311
D03 Melanoma in situ	0.688	0.312
T80 Complications following infusion, transfusion and therapeutic injection	0.688	0.312
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.687	0.313
C95 Leukaemia of unspecified cell type	0.687	0.313
C94 Other leukaemias of specified cell type	0.687	0.313
C93 Monocytic leukaemia	0.687	0.313
C88 Malignant immunoproliferative diseases	0.687	0.313
C86 Other specified types of T/NK-cell lymphoma	0.687	0.313
C84 Peripheral and cutaneous T-cell lymphomas	0.687	0.313
S30 Superficial injury of abdomen, lower back and pelvis	0.687	0.313
H74.4 Polyp of middle ear	0.686	0.314
T79.7 Traumatic subcutaneous emphysema	0.686	0.314
C83.3 Large cell (diffuse)	0.685	0.315
D86 Sarcoidosis	0.685	0.315
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.684	0.316
D68.6 Other Thrombophilia	0.684	0.316
C24.1 Ampulla of Vater	0.683	0.317
T82.3 Mechanical complication of other vascular grafts	0.682	0.318
C26 Malignant neoplasm of other and ill-defined digestive organs	0.681	0.319
D69.9 Haemorrhagic condition, unspecified	0.680	0.319
D69.8 Other specified haemorrhagic conditions	0.680	0.319
D69.4 Other primary thrombocytopenia	0.680	0.319
D69.2 Other nonthrombocytopenic purpura	0.680	0.319
D69.1 Qualitative platelet defects	0.680	0.319
D69.0 Allergic purpura	0.680	0.319
T91.9 Sequelae of unspecified injury of neck and trunk	0.680	0.320
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.680	0.320
H68 Eustachian salpingitis and obstruction	0.680	0.320
H67 Otitis media in diseases classified elsewhere	0.680	0.320
E78.4 Other hyperlipidaemia	0.680	0.320
E23.0 Hypopituitarism	0.680	0.320
M48 Other spondylopathies	0.679	0.321
E10-E14 Diabetes mellitus	0.679	0.321
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.678	0.322
S26 Injury of heart	0.678	0.322
S25 Injury of blood vessels of thorax	0.678	0.322
S24 Injury of nerves and spinal cord at thorax level	0.678	0.322
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.678	0.322
T93.9 Sequelae of unspecified injury of lower limb	0.676	0.323
E53 Deficiency of other B group vitamins	0.676	0.324
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.675	0.325
E87.4 Mixed disorder of acid-base balance	0.674	0.326
C18.3 Hepatic flexure	0.674	0.326
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.671	0.329
L05 Pilonidal cyst	0.668	0.332
S98 Traumatic amputation of ankle and foot	0.668	0.332
S97 Crushing injury of ankle and foot	0.668	0.332
S96 Injury of muscle and tendon at ankle and foot level	0.668	0.332
S95 Injury of blood vessels at ankle and foot level	0.668	0.332
S94 Injury of nerves at ankle and foot level	0.668	0.332
M72.9 Fibroblastic disorder, unspecified	0.667	0.333
M72.8 Other fibroblastic disorders	0.667	0.333
M72.6 Necrotizing fasciitis	0.667	0.333
M72.5 Fasciitis, not elsewhere classified	0.667	0.333
M72.4 Pseudosarcomatous fibromatosis	0.667	0.333
M72.3 Nodular fasciitis	0.667	0.333
M72.1 Knuckle pads	0.667	0.333
T90.4 Sequelae of injury of eye and orbit	0.667	0.333
T90.3 Sequelae of injury of cranial nerves	0.667	0.333
T90.1 Sequelae of open wound of head	0.667	0.333
T90.0 Sequelae of superficial injury of head	0.667	0.333
T88.4 Failed or difficult intubation	0.667	0.333
S20 Superficial injury of thorax	0.665	0.335
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.665	0.335
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.665	0.335
T82.4 Mechanical complication of vascular dialysis catheter	0.665	0.335
T82.0 Mechanical complication of heart valve prosthesis	0.665	0.335
D46.9 Myelodysplastic syndrome, unspecified	0.665	0.335
D68.2 Hereditary deficiency of other clotting factors	0.664	0.335
M93 Other osteochondropathies	0.663	0.336
H74.0 Tympanosclerosis	0.663	0.337
T93.8 Sequelae of other specified injuries of lower limb	0.662	0.337
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.662	0.337
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.662	0.337
T93.4 Sequelae of injury of nerve of lower limb	0.662	0.337
T93.1 Sequelae of fracture of femur	0.662	0.337
T93.0 Sequelae of open wound of lower limb	0.662	0.337
B95-B98 Bacterial, viral and other infectious agents	0.661	0.339
F05 Delirium, not induced by alcohol and other psychoactive substances	0.659	0.341
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.659	0.341
S22.5 Flail chest	0.658	0.342
S22.2 Fracture of sternum	0.658	0.342
C18.6 Descending colon	0.657	0.343
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.657	0.343
Q38-Q45 Other congenital malformations of the digestive system	0.657	0.343
S91.0 Open wound of ankle	0.656	0.344
E78.8 Other disorders of lipoprotein metabolism	0.656	0.344
E89.2 Postprocedural hypoparathyroidism	0.656	0.344
C51 Malignant neoplasm of vulva	0.656	0.344
C32.1 Supraglottis	0.655	0.345
F20 Schizophrenia	0.654	0.346
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.653	0.346
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.653	0.346
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.653	0.346
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.653	0.346
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.653	0.346
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.653	0.346
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.653	0.346
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.653	0.346
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.653	0.346
F80-F89 Disorders of psychological development	0.654	0.346
C24.0 Extrahepatic bile duct	0.653	0.346
M65 Synovitis and tenosynovitis	0.653	0.347
S22.0 Fracture of thoracic vertebra	0.653	0.347
T82.1 Mechanical complication of cardiac electronic device	0.652	0.348
Q60-Q64 Congenital malformations of the urinary system	0.651	0.349
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.651	0.349
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.651	0.349
M71 Other bursopathies	0.651	0.349
C92.0 Acute myeloid leukaemia	0.651	0.349
E87.5 Hyperkalaemia	0.650	0.350
T92.0 Sequelae of open wound of upper limb	0.650	0.350
M94 Other disorders of cartilage	0.650	0.350
C18.4 Transverse colon	0.649	0.350
S22.3 Fracture of rib	0.649	0.351
D47.3 Essential (haemorrhagic) thrombocythaemia	0.648	0.352
C16.0 Cardia	0.648	0.352
D05 Carcinoma in situ of breast	0.648	0.352
T91.3 Sequelae of injury of spinal cord	0.647	0.353
S01 Open wound of head	0.647	0.353
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.646	0.354
M50-M54 Other dorsopathies	0.646	0.354
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.645	0.355
S05 Injury of eye and orbit	0.644	0.355
L10-L14 Bullous disorders	0.644	0.356
F03 Unspecified dementia	0.644	0.356
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.644	0.356
H69.9 Eustachian tube disorder, unspecified	0.644	0.356
E04.0 Non-toxic diffuse goitre	0.644	0.356
Q80-Q89 Other congenital malformations	0.643	0.357
L50-L54 Urticaria and erythema	0.642	0.358
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.642	0.358
C82.6 Cutaneous follicle centre lymphoma	0.642	0.358
C82.5 Diffuse follicle centre lymphoma	0.642	0.358
C82.4 Follicular lymphoma grade IIIb	0.642	0.358
C82.3 Follicular lymphoma grade IIIa	0.642	0.358
C82.2 Large cell, follicular	0.642	0.358
C82.0 Small cleaved cell, follicular	0.642	0.358
E61 Deficiency of other nutrient elements	0.641	0.359
E78.6 Lipoprotein deficiency	0.641	0.359
E78.3 Hyperchylomicronaemia	0.641	0.359
M46 Other inflammatory spondylopathies	0.640	0.360
E28 Ovarian dysfunction	0.639	0.361
E34 Other endocrine disorders	0.639	0.361
C25.0 Head of pancreas	0.638	0.362
D48.6 Breast	0.638	0.362
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.637	0.362
E35 Disorders of endocrine glands in diseases classified elsewhere	0.637	0.363
E32 Diseases of thymus	0.637	0.363
E31 Polyglandular dysfunction	0.637	0.363
E30 Disorders of puberty, not elsewhere classified	0.637	0.363
E26 Hyperaldosteronism	0.637	0.363
E25 Adrenogenital disorders	0.637	0.363
E20 Hypoparathyroidism	0.637	0.363
C54.1 Endometrium	0.636	0.364
C18.5 Splenic flexure	0.636	0.364
Z70-Z76 Persons encountering health services in other circumstances	0.636	0.364
C15 Malignant neoplasm of oesophagus	0.635	0.365
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.635	0.365
L04 Acute lymphadenitis	0.635	0.365
L01 Impetigo	0.635	0.365
L00 Staphylococcal scalded skin syndrome	0.635	0.365
H60 Otitis externa	0.634	0.366
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.634	0.366
C90.2 Plasmacytoma, extramedullary	0.633	0.366
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.633	0.367
D07 Carcinoma in situ of other and unspecified genital organs	0.633	0.367
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.633	0.367
T91.1 Sequelae of fracture of spine	0.633	0.367
M75.8 Other shoulder lesions	0.632	0.368
S32 Fracture of lumbar spine and pelvis	0.631	0.369
H62 Disorders of external ear in diseases classified elsewhere	0.631	0.369
D02 Carcinoma in situ of middle ear and respiratory system	0.630	0.370
D01 Carcinoma in situ of other and unspecified digestive organs	0.630	0.370
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.630	0.370
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.630	0.370
D04.4 Skin of scalp and neck	0.630	0.370
H74.9 Disorder of middle ear and mastoid, unspecified	0.629	0.371
H74.2 Discontinuity and dislocation of ear ossicles	0.629	0.371
H74.1 Adhesive middle ear disease	0.629	0.371
D53 Other nutritional anaemias	0.628	0.371
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.627	0.373
T91.4 Sequelae of injury of intrathoracic organs	0.627	0.373
T91.2 Sequelae of other fracture of thorax and pelvis	0.627	0.373
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.627	0.373
E29 Testicular dysfunction	0.626	0.374
C02 Malignant neoplasm of other and unspecified parts of tongue	0.625	0.374
S70 Superficial injury of hip and thigh	0.625	0.375
S22.40 Multiple fractures of ribs (closed)	0.625	0.375
C10 Malignant neoplasm of oropharynx	0.624	0.376
M75.2 Bicipital tendinitis	0.623	0.377
S10 Superficial injury of neck	0.623	0.377
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.623	0.377
E89.8 Other postprocedural endocrine and metabolic disorders	0.623	0.377
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.623	0.377
E89.5 Postprocedural testicular hypofunction	0.623	0.377
E89.4 Postprocedural ovarian failure	0.623	0.377
E89.1 Postprocedural hypoinsulinaemia	0.623	0.377
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.623	0.377
S12 Fracture of neck	0.623	0.377
E27 Other disorders of adrenal gland	0.622	0.378
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.622	0.378
F70-F79 Mental retardation	0.622	0.378
H74.8 Other specified disorders of middle ear and mastoid	0.621	0.379
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.620	0.380
S06 Intracranial injury	0.620	0.380
L20-L30 Dermatitis and eczema	0.620	0.380
T92.9 Sequelae of unspecified injury of upper limb	0.620	0.380
T92.8 Sequelae of other specified injuries of upper limb	0.620	0.380
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.620	0.380
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.620	0.380
T92.4 Sequelae of injury of nerve of upper limb	0.620	0.380
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.620	0.380
M45 Ankylosing spondylitis	0.620	0.380
T86.1 Kidney transplant failure and rejection	0.619	0.381
E89.3 Postprocedural hypopituitarism	0.618	0.382
S81 Open wound of lower leg	0.618	0.382
E06 Thyroiditis	0.617	0.383
F33 Recurrent depressive disorder	0.617	0.383
M77 Other enthesopathies	0.616	0.384
H61.3 Acquired stenosis of external ear canal	0.616	0.384
H70.9 Mastoiditis, unspecified	0.616	0.384
D48.0 Bone and articular cartilage	0.615	0.384
C90.0 Multiple myeloma	0.615	0.385
E64 Sequelae of malnutrition and other nutritional deficiencies	0.615	0.385
E63 Other nutritional deficiencies	0.615	0.385
E56 Other vitamin deficiencies	0.615	0.385
E51 Thiamine deficiency	0.615	0.385
E50 Vitamin A deficiency	0.615	0.385
E60 Dietary zinc deficiency	0.615	0.385
E59 Dietary selenium deficiency	0.615	0.385
E58 Dietary calcium deficiency	0.615	0.385
E54 Ascorbic acid deficiency	0.615	0.385
E52 Niacin deficiency [pellagra]	0.615	0.385
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.614	0.385
C70 Malignant neoplasm of meninges	0.614	0.385
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.614	0.385
T79.3 Post-traumatic wound infection, not elsewhere classified	0.614	0.386
S22.9 Fracture of bony thorax, part unspecified	0.614	0.386
S22.8 Fracture of other parts of bony thorax	0.614	0.386
S22.1 Multiple fractures of thoracic spine	0.614	0.386
M00 Pyogenic arthritis	0.613	0.387
D52 Folate deficiency anaemia	0.613	0.387
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.612	0.387
E00 Congenital iodine-deficiency syndrome	0.612	0.387
E02 Subclinical iodine-deficiency hypothyroidism	0.612	0.387
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.612	0.387
D75 Other diseases of blood and blood-forming organs	0.612	0.388
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.611	0.389
Q35-Q37 Cleft lip and cleft palate	0.611	0.389
Q30-Q34 Congenital malformations of the respiratory system	0.611	0.389
M40-M43 Deforming dorsopathies	0.611	0.389
D41.9 Urinary organ, unspecified	0.611	0.389
D41.7 Other urinary organs	0.611	0.389
D41.3 Urethra	0.611	0.389
D41.2 Ureter	0.611	0.389
D41.1 Renal pelvis	0.611	0.389
M75.9 Shoulder lesion, unspecified	0.610	0.390
C75 Malignant neoplasm of other endocrine glands and related structures	0.609	0.391
C74 Malignant neoplasm of adrenal gland	0.609	0.391
E05.0 Thyrotoxicosis with diffuse goitre	0.608	0.392
E23.2 Diabetes insipidus	0.608	0.392
T85 Complications of other internal prosthetic devices, implants and grafts	0.608	0.392
H80-H83 Diseases of inner ear	0.607	0.393
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.607	0.393
D48.7 Other specified sites	0.607	0.393
D48.4 Peritoneum	0.607	0.393
D48.3 Retroperitoneum	0.607	0.393
D48.2 Peripheral nerves and autonomic nervous system	0.607	0.393
D68.9 Coagulation defect, unspecified	0.607	0.393
H61.1 Non-infective disorders of pinna	0.607	0.393
C81 Hodgkin's disease	0.607	0.393
C43-C44 Melanoma and other malignant neoplasms of skin	0.607	0.393
Z33 Pregnant state, incidental	0.607	0.393
C32.9 Larynx, unspecified	0.606	0.394
C16.8 Overlapping lesion of stomach	0.605	0.395

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations