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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12051272
log Bayes Factor = 1.61799
Chromosome 16   position 82,663,288  (GRCh37) Explore rs12051272 on Ensembl!
Variant rs12051272 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.973 0.027 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.970 0.030 0.000
Chapter XXI Factors influencing health status and contact with health services
0.967 0.033 0.000
R50-R69 General symptoms and signs
0.963 0.037 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.960 0.040 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.949 0.051 0.000
R51 Headache
0.948 0.052 0.000
R53 Malaise and fatigue
0.937 0.063 0.000
Chapter I Certain infectious and parasitic diseases
0.924 0.076 0.000
S00-S09 Injuries to the head
0.918 0.082 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.880 0.120 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.878 0.122 0.000
B95-B98 Bacterial, viral and other infectious agents
0.874 0.126 0.000
M50-M54 Other dorsopathies
0.873 0.127 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.867 0.133 0.000
M54 Dorsalgia
0.863 0.137 0.000
Chapter X Diseases of the respiratory system
0.857 0.143 0.000
Z47 Other orthopaedic follow-up care
0.857 0.143 0.000
S09 Other and unspecified injuries of head
0.852 0.148 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
S40-S49 Injuries to the shoulder and upper arm
0.847 0.153 0.000
M54.2 Cervicalgia
0.841 0.159 0.000
Z51 Other medical care
0.833 0.167 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.828 0.172 0.000
Z50 Care involving use of rehabilitation procedures
0.827 0.173 0.000
M54.22 Cervicalgia (Cervical region)
0.826 0.174 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.824 0.176 0.000
R54 Senility
0.820 0.180 0.000
R68 Other general symptoms and signs
0.811 0.189 0.000
S70-S79 Injuries to the hip and thigh
0.807 0.192 0.000
S09.9 Unspecified injury of head
0.805 0.195 0.000
S80-S89 Injuries to the knee and lower leg
0.803 0.197 0.000
R58 Haemorrhage, not elsewhere classified
0.798 0.202 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.796 0.204 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.791 0.209 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.791 0.209 0.000
A30-A49 Other bacterial diseases
0.785 0.215 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.784 0.215 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.781 0.219 0.000
R69 Unknown and unspecified causes of morbidity
0.777 0.223 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.775 0.225 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.775 0.225 0.000
Chapter II Neoplasms
0.773 0.227 0.000
Z46 Fitting and adjustment of other devices
0.769 0.230 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
Z48 Other surgical follow-up care
0.765 0.235 0.000
Z50.1 Other physical therapy
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
J90-J94 Other diseases of pleura
0.753 0.247 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.748 0.252 0.000
M50 Cervical disk disorders
0.747 0.253 0.000
Z52 Donors of organs and tissues
0.746 0.254 0.000
R50 Fever of unknown origin
0.746 0.254 0.000
Z45 Adjustment and management of implanted device
0.746 0.254 0.000
Z29 Need for other prophylactic measures
0.741 0.259 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.740 0.260 0.000
J30-J39 Other diseases of upper respiratory tract
0.739 0.261 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.737 0.263 0.000
M54.3 Sciatica
0.735 0.265 0.000
S00 Superficial injury of head
0.733 0.267 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.730 0.270 0.000
Z22 Carrier of infectious disease
0.728 0.272 0.000
M54.5 Low back pain
0.725 0.275 0.000
R59 Enlarged lymph nodes
0.724 0.276 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.723 0.277 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.720 0.280 0.000
R52 Pain, not elsewhere classified
0.719 0.281 0.000
Z43 Attention to artificial openings
0.718 0.282 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
Z51.3 Blood transfusion without reported diagnosis
0.715 0.285 0.000
S02 Fracture of skull and facial bones
0.711 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.290 0.000
Chapter XXII Codes for special purposes
0.707 0.293 0.000
J00-J06 Acute upper respiratory infections
0.705 0.295 0.000
Z72 Problems related to lifestyle
0.704 0.296 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.703 0.297 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.703 0.297 0.000
R68.8 Other specified general symptoms and signs
0.703 0.297 0.000
H90-H95 Other disorders of ear
0.701 0.299 0.000
D50-D53 Nutritional anaemias
0.701 0.299 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.697 0.303 0.000
Z73 Problems related to life-management difficulty
0.697 0.303 0.000
Z75 Problems related to medical facilities and other health care
0.697 0.303 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
S10-S19 Injuries to the neck
0.696 0.304 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.691 0.309 0.000
S72 Fracture of femur
0.691 0.309 0.000
Z50.8 Care involving use of rehabilitation procedures
0.691 0.309 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.690 0.310 0.000
R62 Lack of expected normal physiological development
0.690 0.310 0.000
R57 Shock, not elsewhere classified
0.690 0.310 0.000
R64 Cachexia
0.690 0.310 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.689 0.311 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.689 0.311 0.000
R60 Oedema, not elsewhere classified
0.687 0.313 0.000
Z51.5 Palliative care
0.687 0.313 0.000
H65-H75 Diseases of middle ear and mastoid
0.684 0.316 0.000
R61 Hyperhidrosis
0.683 0.317 0.000
S42 Fracture of shoulder and upper arm
0.682 0.318 0.000
Z54 Convalescence
0.680 0.319 0.000
Z49 Care involving dialysis
0.680 0.319 0.000
Z44 Fitting and adjustment of external prosthetic device
0.680 0.319 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.679 0.321 0.000
S60-S69 Injuries to the wrist and hand
0.678 0.322 0.000
Z41 Procedures for purposes other than remedying health state
0.676 0.324 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.676 0.324 0.000
S50-S59 Injuries to the elbow and forearm
0.674 0.326 0.000
R47-R49 Symptoms and signs involving speech and voice
0.673 0.327 0.000
J91 Pleural effusion in conditions classified elsewhere
0.672 0.328 0.000
S06 Intracranial injury
0.671 0.329 0.000
B35-B49 Mycoses
0.669 0.331 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.668 0.332 0.000
E00-E07 Disorders of thyroid gland
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.666 0.334 0.000
T42.4 Benzodiazepines
0.665 0.335 0.000
S80 Superficial injury of lower leg
0.664 0.336 0.000
Z42 Follow-up care involving plastic surgery
0.663 0.336 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.663 0.337 0.000
B99-B99 Other infectious diseases
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.662 0.338 0.000
B65-B83 Helminthiases
0.662 0.338 0.000
B50-B64 Protozoal diseases
0.662 0.338 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.662 0.338 0.000
B15-B19 Viral hepatitis
0.662 0.338 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.662 0.338 0.000
A75-A79 Rickettsioses
0.662 0.338 0.000
A70-A74 Other diseases caused by chlamydiae
0.662 0.338 0.000
A65-A69 Other spirochaetal diseases
0.662 0.338 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.662 0.338 0.000
A20-A28 Certain zoonotic bacterial diseases
0.662 0.338 0.000
A15-A19 Tuberculosis
0.662 0.338 0.000
S08 Traumatic amputation of part of head
0.658 0.341 0.000
S07 Crushing injury of head
0.658 0.341 0.000
S05 Injury of eye and orbit
0.658 0.341 0.000
S04 Injury of cranial nerves
0.658 0.341 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.658 0.341 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.658 0.342 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.656 0.344 0.000
Z72.1 Alcohol use
0.655 0.345 0.000
E20-E35 Disorders of other endocrine glands
0.655 0.345 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.650 0.350 0.000
S01 Open wound of head
0.649 0.351 0.000
M45-M49 Spondylopathies
0.649 0.351 0.000
M05-M14 Inflammatory polyarthropathies
0.647 0.353 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.642 0.358 0.000
Z46.6 Fitting and adjustment of urinary device
0.641 0.359 0.000
Chapter XX External causes of morbidity and mortality
0.639 0.361 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.638 0.362 0.000
A49 Bacterial infection of unspecified site
0.637 0.363 0.000
A41 Other septicaemia
0.637 0.363 0.000
R63 Symptoms and signs concerning food and fluid intake
0.636 0.364 0.000
S32 Fracture of lumbar spine and pelvis
0.635 0.365 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.633 0.367 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.632 0.368 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.631 0.369 0.000
M91-M94 Chondropathies
0.631 0.369 0.000
M86-M90 Other osteopathies
0.631 0.369 0.000
M60-M63 Disorders of muscles
0.631 0.369 0.000
M00-M03 Infectious arthropathies
0.631 0.369 0.000
H60-H62 Diseases of external ear
0.631 0.369 0.000
T90 Sequelae of injuries of head
0.630 0.370 0.000
Z76 Persons encountering health services in other circumstances
0.629 0.371 0.000
Z74 Problems related to care-provider dependency
0.629 0.371 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.629 0.371 0.000
Z51.0 Radiotherapy session
0.629 0.371 0.000
M54.59 Low back pain (Site unspecified)
0.629 0.371 0.000
J20-J22 Other acute lower respiratory infections
0.628 0.372 0.000
S43.0 Dislocation of shoulder joint
0.628 0.372 0.000
Z22.3 Carrier of other specified bacterial diseases
0.627 0.372 0.000
T92 Sequelae of injuries of upper limb
0.627 0.373 0.000
Z48.0 Attention to surgical dressings and sutures
0.627 0.373 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.627 0.373 0.000
M53 Other dorsopathies, not elsewhere classified
0.626 0.374 0.000
M50.1 Cervical disk disorder with radiculopathy
0.626 0.374 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.623 0.377 0.000
Z45.8 Adjustment and management of other implanted devices
0.623 0.377 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.623 0.377 0.000
Z40 Prophylactic surgery
0.622 0.378 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.622 0.378 0.000
Z28 Immunisation not carried out
0.622 0.378 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.622 0.378 0.000
Z26 Need for immunisation against other single infectious diseases
0.622 0.378 0.000
Z25 Need for immunisation against other single viral diseases
0.622 0.378 0.000
Z24 Need for immunisation against certain single viral diseases
0.622 0.378 0.000
Z23 Need for immunisation against single bacterial diseases
0.622 0.378 0.000
Z20 Contact with and exposure to communicable diseases
0.622 0.378 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.622 0.378 0.000
Z13 Special screening examination for other diseases and disorders
0.621 0.379 0.000
M54.8 Other dorsalgia
0.619 0.381 0.000
M54.6 Pain in thoracic spine
0.619 0.381 0.000
M54.4 Lumbago with sciatica
0.619 0.381 0.000
M54.1 Radiculopathy
0.619 0.381 0.000
M54.0 Panniculitis affecting regions of neck and back
0.619 0.381 0.000
C51-C58 Malignant neoplasms of female genital organs
0.619 0.381 0.000
M51 Other intervertebral disk disorders
0.618 0.382 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.618 0.382 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.618 0.382 0.000
M54.39 Sciatica (Site unspecified)
0.617 0.383 0.000
H80-H83 Diseases of inner ear
0.617 0.383 0.000
R56 Convulsions, not elsewhere classified
0.616 0.384 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.615 0.385 0.000
E04 Other non-toxic goitre
0.615 0.385 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.614 0.386 0.000
Z47.8 Other specified orthopaedic follow-up care
0.614 0.386 0.000
Z30 Contraceptive management
0.614 0.386 0.000
Z29.1 Prophylactic immunotherapy
0.612 0.388 0.000
J09-J18 Influenza and pneumonia
0.611 0.388 0.000
S09.8 Other specified injuries of head
0.611 0.389 0.000
S09.7 Multiple injuries of head
0.611 0.389 0.000
S09.2 Traumatic rupture of ear drum
0.611 0.389 0.000
S09.1 Injury of muscle and tendon of head
0.611 0.389 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.611 0.389 0.000
S81 Open wound of lower leg
0.610 0.390 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.610 0.390 0.000
D50 Iron deficiency anaemia
0.608 0.392 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.607 0.392 0.000
S48 Traumatic amputation of shoulder and upper arm
0.607 0.392 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.607 0.392 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.607 0.392 0.000
S44 Injury of nerves at shoulder and upper arm level
0.607 0.392 0.000
S41 Open wound of shoulder and upper arm
0.607 0.392 0.000
S40 Superficial injury of shoulder and upper arm
0.607 0.392 0.000
S47 Crushing injury of shoulder and upper arm
0.607 0.392 0.000
Z02 Examination and encounter for administrative purposes
0.607 0.393 0.000
R52.2 Other chronic pain
0.605 0.395 0.000
E50-E64 Other nutritional deficiencies
0.605 0.395 0.000
M54.29 Cervicalgia-Site unspe
0.603 0.397 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.603 0.397 0.000
M54.27 Cervicalgia-Lumbosacral
0.603 0.397 0.000
M54.26 Cervicalgia-Lumbar
0.603 0.397 0.000
M54.25 Cervicalgia-Thoracolumbar
0.603 0.397 0.000
M54.24 Cervicalgia-Thoracic
0.603 0.397 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.603 0.397 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.603 0.397 0.000
M54.20 Cervicalgia-Mult site
0.603 0.397 0.000
J34 Other disorders of nose and nasal sinuses
0.601 0.399 0.000
Z52.4 Kidney donor
0.601 0.399 0.000
J93 Pneumothorax
0.600 0.400 0.000
D80-D89 Certain disorders involving the immune mechanism
0.600 0.400 0.000
T78 Adverse effects, not elsewhere classified
0.599 0.401 0.000
R50.8 Other specified fever
0.599 0.401 0.000
C15-C26 Malignant neoplasms of digestive organs
0.599 0.401 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.598 0.402 0.000
Z51.9 Medical care, unspecified
0.597 0.403 0.000
Z51.6 Desensitisation to allergens
0.597 0.403 0.000
J92 Pleural plaque
0.596 0.404 0.000
Z29.0 Isolation
0.594 0.406 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.593 0.406 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.593 0.406 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.593 0.406 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.593 0.406 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.593 0.406 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.593 0.406 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.593 0.406 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.593 0.406 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.593 0.406 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.593 0.406 0.000
T36 Poisoning by systemic antibiotics
0.593 0.406 0.000
Z50.6 Orthoptic training
0.593 0.407 0.000
Z50.5 Speech therapy
0.593 0.407 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.593 0.407 0.000
Z50.3 Drug rehabilitation
0.593 0.407 0.000
Z50.2 Alcohol rehabilitation
0.593 0.407 0.000
M50.3 Other cervical disk degeneration
0.592 0.408 0.000
J60-J70 Lung diseases due to external agents
0.591 0.409 0.000
D55-D59 Haemolytic anaemias
0.590 0.409 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.589 0.410 0.000
R59.1 Generalised enlarged lymph nodes
0.589 0.410 0.000
J00 Acute nasopharyngitis [common cold]
0.589 0.411 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.589 0.411 0.000
J30 Vasomotor and allergic rhinitis
0.588 0.412 0.000
R25 Abnormal involuntary movements
0.586 0.413 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.585 0.415 0.000
R27 Other lack of coordination
0.584 0.416 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.584 0.416 0.000
S42.2 Fracture of upper end of humerus
0.583 0.417 0.000
M54.9 Dorsalgia, unspecified
0.583 0.417 0.000
R68.3 Clubbing of fingers
0.582 0.418 0.000
R68.2 Dry mouth, unspecified
0.582 0.418 0.000
R68.1 Nonspecific symptoms peculiar to infancy
0.582 0.418 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.582 0.418 0.000
S00.1 Contusion of eyelid and periocular area
0.581 0.418 0.000
S79 Other and unspecified injuries of hip and thigh
0.579 0.421 0.000
S78 Traumatic amputation of hip and thigh
0.579 0.421 0.000
S77 Crushing injury of hip and thigh
0.579 0.421 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.579 0.421 0.000
S75 Injury of blood vessels at hip and thigh level
0.579 0.421 0.000
S74 Injury of nerves at hip and thigh level
0.579 0.421 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.579 0.421 0.000
S71 Open wound of hip and thigh
0.579 0.421 0.000
S70 Superficial injury of hip and thigh
0.579 0.421 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.578 0.422 0.000
Q60-Q64 Congenital malformations of the urinary system
0.577 0.422 0.000
S89 Other and unspecified injuries of lower leg
0.576 0.424 0.000
S88 Traumatic amputation of lower leg
0.576 0.424 0.000
S87 Crushing injury of lower leg
0.576 0.424 0.000
S86 Injury of muscle and tendon at lower leg level
0.576 0.424 0.000
S85 Injury of blood vessels at lower leg level
0.576 0.424 0.000
S84 Injury of nerves at lower leg level
0.576 0.424 0.000
R79 Other abnormal findings of blood chemistry
0.576 0.424 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.576 0.424 0.000
B25-B34 Other viral diseases
0.575 0.425 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.574 0.425 0.000
A00-A09 Intestinal infectious diseases
0.574 0.426 0.000
M54.36 Sciatica (Lumbar region)
0.573 0.427 0.000
Z13.9 Special screening examination, unspecified
0.573 0.427 0.000
M65-M68 Disorders of synovium and tendon
0.573 0.427 0.000
Z30.2 Sterilisation
0.572 0.428 0.000
J32 Chronic sinusitis
0.572 0.428 0.000
S72.1 Pertrochanteric fracture
0.572 0.428 0.000
Chapter XIV Diseases of the genitourinary system
0.571 0.429 0.000
T98 Sequelae of other and unspecified effects of external causes
0.571 0.429 0.000
T95 Sequelae of burns, corrosions and frostbite
0.571 0.429 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.571 0.429 0.000
T93 Sequelae of injuries of lower limb
0.571 0.429 0.000
T91 Sequelae of injuries of neck and trunk
0.571 0.429 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.571 0.429 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.571 0.429 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.571 0.429 0.000
J81 Pulmonary oedema
0.570 0.429 0.000
H92 Otalgia and effusion of ear
0.570 0.430 0.000
S00.8 Superficial injury of other parts of head
0.569 0.431 0.000
Z36 Antenatal screening
0.568 0.432 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.568 0.432 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.568 0.432 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.568 0.432 0.000
M80-M85 Disorders of bone density and structure
0.568 0.432 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.567 0.433 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.567 0.433 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.567 0.433 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.567 0.433 0.000
H65 Nonsuppurative otitis media
0.565 0.435 0.000
M41 Scoliosis
0.564 0.436 0.000
R50.0 Fever with chills
0.564 0.436 0.000
D00-D09 In situ neoplasms
0.563 0.437 0.000
A48 Other bacterial diseases, not elsewhere classified
0.563 0.437 0.000
A44 Bartonellosis
0.563 0.437 0.000
A43 Nocardiosis
0.563 0.437 0.000
A42 Actinomycosis
0.563 0.437 0.000
A40 Streptococcal septicaemia
0.563 0.437 0.000
A39 Meningococcal infection
0.563 0.437 0.000
A37 Whooping cough
0.563 0.437 0.000
A36 Diphtheria
0.563 0.437 0.000
A32 Listeriosis
0.563 0.437 0.000
A31 Infection due to other mycobacteria
0.563 0.437 0.000
A30 Leprosy [Hansen's disease]
0.563 0.437 0.000
A46 Erysipelas
0.563 0.437 0.000
A38 Scarlet fever
0.563 0.437 0.000
A35 Other tetanus
0.563 0.437 0.000
A34 Obstetrical tetanus
0.563 0.437 0.000
A33 Tetanus neonatorum
0.563 0.437 0.000
Z57 Occupational exposure to risk-factors
0.562 0.437 0.000
S27 Injury of other and unspecified intrathoracic organs
0.561 0.438 0.000
Z51.2 Other chemotherapy
0.561 0.439 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.561 0.439 0.000
Z71.8 Other specified counselling
0.560 0.440 0.000
J35 Chronic diseases of tonsils and adenoids
0.560 0.440 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.560 0.440 0.000
R77 Other abnormalities of plasma proteins
0.560 0.440 0.000
R76 Other abnormal immunological findings in serum
0.560 0.440 0.000
R74 Abnormal serum enzyme levels
0.560 0.440 0.000
R73 Elevated blood glucose level
0.560 0.440 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.560 0.440 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.560 0.440 0.000
R71 Abnormality of red blood cells
0.560 0.440 0.000
J02 Acute pharyngitis
0.559 0.440 0.000
M43 Other deforming dorsopathies
0.559 0.441 0.000
A87 Viral meningitis
0.558 0.441 0.000
Z48.8 Other specified surgical follow-up care
0.557 0.443 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.556 0.444 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.555 0.444 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.555 0.444 0.000
S37 Injury of urinary and pelvic organs
0.555 0.444 0.000
S36 Injury of intra-abdominal organs
0.555 0.444 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.555 0.444 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.555 0.444 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.555 0.444 0.000
S31 Open wound of abdomen, lower back and pelvis
0.555 0.444 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.555 0.444 0.000
E40-E46 Malnutrition
0.555 0.445 0.000
Chapter V Mental and behavioural disorders
0.555 0.445 0.000
N10-N16 Renal tubulo-interstitial diseases
0.555 0.445 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.554 0.446 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.554 0.446 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.554 0.446 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.554 0.446 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.554 0.446 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.554 0.446 0.000
S72.0 Fracture of neck of femur
0.554 0.446 0.000
Z50.0 Cardiac rehabilitation
0.553 0.447 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.553 0.447 0.000
Z43.3 Attention to colostomy
0.552 0.448 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.552 0.448 0.000
Z46.8 Fitting and adjustment of other specified devices
0.552 0.448 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.552 0.448 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.552 0.448 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.552 0.448 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.552 0.448 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.552 0.448 0.000
Z46.1 Fitting and adjustment of hearing aid
0.552 0.448 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.552 0.448 0.000
S29 Other and unspecified injuries of thorax
0.551 0.449 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.551 0.449 0.000
S26 Injury of heart
0.551 0.449 0.000
S25 Injury of blood vessels of thorax
0.551 0.449 0.000
S24 Injury of nerves and spinal cord at thorax level
0.551 0.449 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.551 0.449 0.000
S21 Open wound of thorax
0.551 0.449 0.000
S20 Superficial injury of thorax
0.551 0.449 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.550 0.450 0.000
D50.9 Iron deficiency anaemia, unspecified
0.550 0.450 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.549 0.451 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.548 0.451 0.000
Z48.9 Surgical follow-up care, unspecified
0.548 0.452 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.547 0.453 0.000
D69 Purpura and other haemorrhagic conditions
0.547 0.453 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.547 0.453 0.000
C80 Malignant neoplasm without specification of site
0.545 0.455 0.000
S51 Open wound of forearm
0.544 0.456 0.000
S02.6 Fracture of mandible
0.544 0.456 0.000
Z35 Supervision of high-risk pregnancy
0.543 0.457 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.543 0.457 0.000
Z33 Pregnant state, incidental
0.542 0.458 0.000
E04.9 Non-toxic goitre, unspecified
0.542 0.458 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.541 0.459 0.000
T75 Effects of other external causes
0.540 0.459 0.000
T74 Maltreatment syndromes
0.540 0.459 0.000
T73 Effects of other deprivation
0.540 0.459 0.000
T70 Effects of air pressure and water pressure
0.540 0.459 0.000
T69 Other effects of reduced temperature
0.540 0.459 0.000
T67 Effects of heat and light
0.540 0.459 0.000
T71 Asphyxiation
0.540 0.459 0.000
T68 Hypothermia
0.540 0.459 0.000
T66 Unspecified effects of radiation
0.540 0.459 0.000
J94 Other pleural conditions
0.540 0.460 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.540 0.460 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.539 0.461 0.000
A41.9 Septicaemia, unspecified
0.537 0.462 0.000
Z02.8 Other examinations for administrative purposes
0.537 0.463 0.000
N13 Obstructive and reflux uropathy
0.537 0.463 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.536 0.463 0.000
Q80-Q89 Other congenital malformations
0.536 0.463 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.536 0.463 0.000
Q50-Q56 Congenital malformations of genital organs
0.536 0.463 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.536 0.463 0.000
Q35-Q37 Cleft lip and cleft palate
0.536 0.463 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.536 0.463 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.536 0.463 0.000
Q00-Q07 Congenital malformations of the nervous system
0.536 0.463 0.000
H91 Other hearing loss
0.536 0.463 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.536 0.464 0.000
S02.2 Fracture of nasal bones
0.536 0.464 0.000
M50.9 Cervical disk disorder, unspecified
0.535 0.465 0.000
M50.8 Other cervical disk disorders
0.535 0.465 0.000
M50.0 Cervical disk disorder with myelopathy
0.535 0.465 0.000
Z52.9 Donor of unspecified organ or tissue
0.535 0.465 0.000
Z52.8 Donor of other organs and tissues
0.535 0.465 0.000
Z52.7 Heart donor
0.535 0.465 0.000
Z52.6 Liver donor
0.535 0.465 0.000
Z52.5 Cornea donor
0.535 0.465 0.000
Z52.3 Bone marrow donor
0.535 0.465 0.000
Z52.2 Bone donor
0.535 0.465 0.000
Z52.1 Skin donor
0.535 0.465 0.000
Z52.0 Blood donor
0.535 0.465 0.000
R50.2 Drug-induced fever
0.535 0.465 0.000
R50.1 Persistent fever
0.535 0.465 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.535 0.465 0.000
Z45.3 Adjustment and management of implanted hearing device
0.535 0.465 0.000
Z45.1 Adjustment and management of infusion pump
0.535 0.465 0.000
C16 Malignant neoplasm of stomach
0.534 0.466 0.000
S01.5 Open wound of lip and oral cavity
0.534 0.466 0.000
D60-D64 Aplastic and other anaemias
0.533 0.467 0.000
S82 Fracture of lower leg, including ankle
0.533 0.467 0.000
Chapter IX Diseases of the circulatory system
0.532 0.468 0.000
S62 Fracture at wrist and hand level
0.532 0.468 0.000
Z29.9 Prophylactic measure, unspecified
0.531 0.468 0.000
Z29.8 Other specified prophylactic measures
0.531 0.468 0.000
Z29.2 Other prophylactic chemotherapy
0.531 0.468 0.000
M50.2 Other cervical disk displacement
0.530 0.470 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.530 0.470 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.530 0.470 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.530 0.470 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.530 0.470 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.530 0.470 0.000
J39 Other diseases of upper respiratory tract
0.530 0.470 0.000
J37 Chronic laryngitis and laryngotracheitis
0.530 0.470 0.000
J36 Peritonsillar abscess
0.530 0.470 0.000
Z71.3 Dietary counselling and surveillance
0.529 0.471 0.000
Z39 Postpartum care and examination
0.528 0.472 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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