TreeWAS – Variant ID: rs12443701

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
M15-M19 Arthrosis	1.000	0.000
M16 Coxarthrosis [arthrosis of hip]	0.999	0.001
J95-J99 Other diseases of the respiratory system	0.997	0.003
Chapter V Mental and behavioural disorders	0.997	0.003
E70-E90 Metabolic disorders	0.996	0.004
J98 Other respiratory disorders	0.996	0.004
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.995	0.005
M16.1 Other primary coxarthrosis	0.994	0.006
M20-M25 Other joint disorders	0.993	0.007
Chapter II Neoplasms	0.993	0.007
M16.9 Coxarthrosis, unspecified	0.988	0.012
Chapter XXI Factors influencing health status and contact with health services	0.985	0.015
E87 Other disorders of fluid, electrolyte and acid-base balance	0.984	0.016
F10 Mental and behavioural disorders due to use of alcohol	0.984	0.016
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.977	0.023
J98.1 Pulmonary collapse	0.976	0.024
C43-C44 Melanoma and other malignant neoplasms of skin	0.972	0.028
Chapter XV Pregnancy, childbirth and the puerperium	0.972	0.028
C34 Malignant neoplasm of bronchus and lung	0.966	0.034
Z40-Z54 Persons encountering health services for specific procedures and health care	0.961	0.039
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.957	0.043
M20 Acquired deformities of fingers and toes	0.956	0.044
Z46 Fitting and adjustment of other devices	0.954	0.046
J09-J18 Influenza and pneumonia	0.954	0.046
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.952	0.048
Z46.6 Fitting and adjustment of urinary device	0.950	0.050
Chapter XIV Diseases of the genitourinary system	0.945	0.055
F17 Mental and behavioural disorders due to use of tobacco	0.940	0.060
N10-N16 Renal tubulo-interstitial diseases	0.936	0.064
J98.4 Other disorders of lung	0.928	0.072
C34.9 Bronchus or lung, unspecified	0.927	0.073
D60-D64 Aplastic and other anaemias	0.927	0.073
S00-S09 Injuries to the head	0.925	0.075
C44 Other malignant neoplasms of skin	0.923	0.077
E20-E35 Disorders of other endocrine glands	0.922	0.078
J20-J22 Other acute lower respiratory infections	0.917	0.083
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.915	0.085
Chapter VIII Diseases of the ear and mastoid process	0.914	0.086
F10.1 Harmful use	0.914	0.086
N13 Obstructive and reflux uropathy	0.909	0.091
F17.1 Harmful use	0.908	0.092
E87.6 Hypokalaemia	0.905	0.095
J18 Pneumonia, organism unspecified	0.904	0.096
M05-M14 Inflammatory polyarthropathies	0.903	0.097
J98.0 Diseases of bronchus, not elsewhere classified	0.900	0.100
E87.5 Hyperkalaemia	0.900	0.100
M45-M49 Spondylopathies	0.898	0.102
M86-M90 Other osteopathies	0.897	0.103
M25 Other joint disorders, not elsewhere classified	0.896	0.104
C64-C68 Malignant neoplasms of urinary tract	0.890	0.110
M23 Internal derangement of knee	0.890	0.110
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.887	0.113
C43 Malignant melanoma of skin	0.886	0.114
S00 Superficial injury of head	0.878	0.122
E83 Disorders of mineral metabolism	0.872	0.128
C34.3 Lower lobe, bronchus or lung	0.870	0.130
N17-N19 Renal failure	0.870	0.130
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.870	0.130
C44.7 Skin of lower limb, including hip	0.869	0.131
F10.2 Dependence syndrome	0.866	0.134
Chapter IX Diseases of the circulatory system	0.865	0.135
F10.3 Withdrawal state	0.864	0.136
M65-M68 Disorders of synovium and tendon	0.861	0.139
J18.9 Pneumonia, unspecified	0.860	0.140
J22 Unspecified acute lower respiratory infection	0.857	0.143
M19 Other arthrosis	0.856	0.143
I30-I52 Other forms of heart disease	0.855	0.145
M13 Other arthritis	0.849	0.151
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.846	0.154
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.846	0.154
Chapter XXII Codes for special purposes	0.842	0.158
E50-E64 Other nutritional deficiencies	0.841	0.159
Chapter XX External causes of morbidity and mortality	0.836	0.164
D63 Anaemia in chronic diseases classified elsewhere	0.836	0.164
D64 Other anaemias	0.834	0.166
N20-N23 Urolithiasis	0.832	0.168
C43.5 Malignant melanoma of trunk	0.831	0.169
H65-H75 Diseases of middle ear and mastoid	0.830	0.170
C44.3 Skin of other and unspecified parts of face	0.829	0.171
E65-E68 Obesity and other hyperalimentation	0.829	0.171
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.827	0.173
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.825	0.175
M20.4 Other hammer toe(s) (acquired)	0.823	0.177
F10.0 Acute intoxication	0.821	0.179
I35 Nonrheumatic aortic valve disorders	0.821	0.179
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.819	0.181
O60-O75 Complications of labour and delivery	0.818	0.182
E89.0 Postprocedural hypothyroidism	0.818	0.182
C64 Malignant neoplasm of kidney, except renal pelvis	0.817	0.183
C15-C26 Malignant neoplasms of digestive organs	0.815	0.185
M13.9 Arthritis, unspecified	0.811	0.189
Z00-Z13 Persons encountering health services for examination and investigation	0.810	0.190
T66-T78 Other and unspecified effects of external causes	0.808	0.192
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.807	0.193
M16.3 Other dysplastic coxarthrosis	0.806	0.194
I45 Other conduction disorders	0.805	0.195
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.802	0.198
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.800	0.200
O94-O99 Other obstetric conditions, not elsewhere classified	0.798	0.202
C34.1 Upper lobe, bronchus or lung	0.798	0.202
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.797	0.203
N13.5 Kinking and stricture of ureter without hydronephrosis	0.796	0.204
Chapter I Certain infectious and parasitic diseases	0.796	0.204
Z12 Special screening examination for neoplasms	0.794	0.206
M46 Other inflammatory spondylopathies	0.792	0.208
E10-E14 Diabetes mellitus	0.790	0.210
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.789	0.211
M20.1 Hallux valgus (acquired)	0.789	0.211
I35.0 Aortic (valve) stenosis	0.788	0.212
N18 Chronic renal failure	0.788	0.212
M45 Ankylosing spondylitis	0.788	0.212
O00-O08 Pregnancy with abortive outcome	0.788	0.212
E22 Hyperfunction of pituitary gland	0.786	0.214
M25.4 Effusion of joint	0.786	0.214
M80-M85 Disorders of bone density and structure	0.784	0.216
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.784	0.216
M20.3 Other deformity of hallux (acquired)	0.782	0.218
M20.5 Other deformities of toe(s) (acquired)	0.781	0.219
E87.7 Fluid overload	0.780	0.220
J95 Postprocedural respiratory disorders, not elsewhere classified	0.780	0.220
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.779	0.221
J14 Pneumonia due to Haemophilus influenzae	0.779	0.221
M20.6 Acquired deformity of toe(s), unspecified	0.778	0.222
E86 Volume depletion	0.775	0.225
E87.0 Hyperosmolality and hypernatraemia	0.774	0.226
F99-F99 Unspecified mental disorder	0.774	0.226
M00-M03 Infectious arthropathies	0.773	0.227
Z12.1 Special screening examination for neoplasm of intestinal tract	0.771	0.229
E83.1 Disorders of iron metabolism	0.770	0.230
Q20-Q28 Congenital malformations of the circulatory system	0.768	0.231
S09 Other and unspecified injuries of head	0.767	0.233
D64.9 Anaemia, unspecified	0.767	0.233
M19.9 Arthrosis, unspecified	0.764	0.236
O85-O92 Complications predominantly related to the puerperium	0.762	0.238
Z43 Attention to artificial openings	0.761	0.239
C44.9 Malignant neoplasm of skin, unspecified	0.760	0.240
E89.3 Postprocedural hypopituitarism	0.760	0.240
M24 Other specific joint derangements	0.759	0.241
Z40 Prophylactic surgery	0.758	0.242
Z41 Procedures for purposes other than remedying health state	0.757	0.243
D80-D89 Certain disorders involving the immune mechanism	0.756	0.244
N13.8 Other obstructive and reflux uropathy	0.755	0.245
N17 Acute renal failure	0.751	0.249
M22 Disorders of patella	0.751	0.249
M16.0 Primary coxarthrosis, bilateral	0.750	0.250
O80-O84 Delivery	0.749	0.251
S00.9 Superficial injury of head, part unspecified	0.748	0.252
J98.8 Other specified respiratory disorders	0.748	0.252
M21 Other acquired deformities of limbs	0.746	0.254
Z52 Donors of organs and tissues	0.745	0.255
I51 Complications and ill-defined descriptions of heart disease	0.744	0.256
T79-T79 Certain early complications of trauma	0.744	0.256
O69 Labour and delivery complicated by umbilical cord complications	0.742	0.258
Z82.3 Family history of stroke	0.741	0.259
C51-C58 Malignant neoplasms of female genital organs	0.739	0.261
M25.7 Osteophyte	0.738	0.262
D63.8 Anaemia in other chronic diseases classified elsewhere	0.737	0.263
S90-S99 Injuries to the ankle and foot	0.736	0.263
H90-H95 Other disorders of ear	0.735	0.265
M67 Other disorders of synovium and tendon	0.735	0.265
Z89 Acquired absence of limb	0.735	0.265
D61 Other aplastic anaemias	0.735	0.265
O36 Maternal care for other known or suspected foetal problems	0.733	0.267
I45.6 Preexcitation syndrome	0.732	0.268
S00.8 Superficial injury of other parts of head	0.730	0.270
I44 Atrioventricular and left bundle-branch block	0.729	0.271
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.727	0.273
D62 Acute posthaemorrhagic anaemia	0.727	0.273
Z49 Care involving dialysis	0.727	0.273
E83.3 Disorders of phosphorus metabolism	0.726	0.274
C44.6 Skin of upper limb, including shoulder	0.725	0.275
Z93 Artificial opening status	0.725	0.275
E80 Disorders of porphyrin and bilirubin metabolism	0.724	0.276
E87.1 Hypo-osmolality and hyponatraemia	0.723	0.277
M89 Other disorders of bone	0.723	0.277
Z42 Follow-up care involving plastic surgery	0.722	0.278
O20-O29 Other maternal disorders predominantly related to pregnancy	0.722	0.278
D50-D53 Nutritional anaemias	0.720	0.280
Z95 Presence of cardiac and vascular implants and grafts	0.720	0.280
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.719	0.281
Z50 Care involving use of rehabilitation procedures	0.719	0.281
M23.2 Derangement of meniscus due to old tear or injury	0.719	0.281
N18.3 Chronic kidney disease, stage 3	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
M15 Polyarthrosis	0.717	0.283
Z54 Convalescence	0.717	0.283
M16.7 Other secondary coxarthrosis	0.717	0.283
M16.6 Other secondary coxarthrosis, bilateral	0.717	0.283
M16.5 Other posttraumatic coxarthrosis	0.717	0.283
M16.4 Posttraumatic coxarthrosis, bilateral	0.717	0.283
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.717	0.283
M86 Osteomyelitis	0.716	0.283
Z92 Personal history of medical treatment	0.716	0.284
M46.9 Inflammatory spondylopathy, unspecified	0.716	0.284
J99 Respiratory disorders in diseases classified elsewhere	0.715	0.285
J96 Respiratory failure, not elsewhere classified	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F80-F89 Disorders of psychological development	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
F60-F69 Disorders of adult personality and behaviour	0.715	0.285
E88 Other metabolic disorders	0.714	0.286
E85 Amyloidosis	0.714	0.286
E84 Cystic fibrosis	0.714	0.286
E79 Disorders of purine and pyrimidine metabolism	0.714	0.286
E77 Disorders of glycoprotein metabolism	0.714	0.286
E76 Disorders of glycosaminoglycan metabolism	0.714	0.286
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.714	0.286
E74 Other disorders of carbohydrate metabolism	0.714	0.286
E73 Lactose intolerance	0.714	0.286
E72 Other disorders of amino-acid metabolism	0.714	0.286
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.714	0.286
E70 Disorders of aromatic amino-acid metabolism	0.714	0.286
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.714	0.286
M13.90 Arthritis, unspecified (Multiple sites)	0.714	0.286
J98.9 Respiratory disorder, unspecified	0.714	0.286
J98.6 Disorders of diaphragm	0.714	0.286
J98.5 Diseases of mediastinum, not elsewhere classified	0.714	0.286
J98.3 Compensatory emphysema	0.714	0.286
J98.2 Interstitial emphysema	0.714	0.286
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.713	0.287
F18 Mental and behavioural disorders due to use of volatile solvents	0.713	0.287
F16 Mental and behavioural disorders due to use of hallucinogens	0.713	0.287
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.713	0.287
F14 Mental and behavioural disorders due to use of cocaine	0.713	0.287
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.713	0.287
F12 Mental and behavioural disorders due to use of cannabinoids	0.713	0.287
F11 Mental and behavioural disorders due to use of opioids	0.713	0.287
M23.3 Other meniscus derangements	0.713	0.287
S06 Intracranial injury	0.712	0.288
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.288
M34 Systemic sclerosis	0.712	0.288
M33 Dermatopolymyositis	0.712	0.288
M32 Systemic lupus erythematosus	0.712	0.288
M30 Polyarteritis nodosa and related conditions	0.712	0.288
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.712	0.288
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.712	0.288
C40-C41 Malignant neoplasms of bone and articular cartilage	0.712	0.288
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.712	0.288
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.711	0.289
E55 Vitamin D deficiency	0.710	0.290
M88 Paget's disease of bone [osteitis deformans]	0.710	0.290
M45.X9 Ankylosing spondylitis (Site unspecified)	0.709	0.291
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.708	0.292
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
W00-W19 Falls	0.707	0.293
M25.46 Effusion of joint (Lower leg)	0.707	0.293
E66 Obesity	0.707	0.293
E87.4 Mixed disorder of acid-base balance	0.706	0.294
E87.3 Alkalosis	0.706	0.294
F10.9 Unspecified mental and behavioural disorder	0.706	0.294
F10.8 Other mental and behavioural disorders	0.706	0.294
F10.7 Residual and late-onset psychotic disorder	0.706	0.294
F10.6 Amnesic syndrome	0.706	0.294
F10.5 Psychotic disorder	0.706	0.294
F10.4 Withdrawal state with delirium	0.706	0.294
M11 Other crystal arthropathies	0.705	0.295
N23 Unspecified renal colic	0.705	0.295
Z45 Adjustment and management of implanted device	0.703	0.297
E87.2 Acidosis	0.703	0.297
M13.97 Arthritis, unspecified (Ankle and foot)	0.702	0.297
N10 Acute tubulo-interstitial nephritis	0.702	0.298
Z22 Carrier of infectious disease	0.701	0.299
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.700	0.299
C38 Malignant neoplasm of heart, mediastinum and pleura	0.700	0.299
C32 Malignant neoplasm of larynx	0.700	0.299
C31 Malignant neoplasm of accessory sinuses	0.700	0.299
C30 Malignant neoplasm of nasal cavity and middle ear	0.700	0.299
C37 Malignant neoplasm of thymus	0.700	0.299
C33 Malignant neoplasm of trachea	0.700	0.299
T78 Adverse effects, not elsewhere classified	0.700	0.300
H72 Perforation of tympanic membrane	0.700	0.300
E16 Other disorders of pancreatic internal secretion	0.699	0.301
F20 Schizophrenia	0.698	0.301
J80-J84 Other respiratory diseases principally affecting the interstitium	0.697	0.303
S01 Open wound of head	0.697	0.303
S50-S59 Injuries to the elbow and forearm	0.697	0.303
D37-D48 Neoplasms of uncertain or unknown behaviour	0.697	0.303
S40-S49 Injuries to the shoulder and upper arm	0.696	0.304
H80-H83 Diseases of inner ear	0.696	0.304
S00.2 Other superficial injuries of eyelid and periocular area	0.695	0.305
J18.1 Lobar pneumonia, unspecified	0.695	0.305
M87 Osteonecrosis	0.694	0.306
E28 Ovarian dysfunction	0.693	0.307
C34.8 Overlapping lesion of bronchus and lung	0.692	0.308
C34.2 Middle lobe, bronchus or lung	0.692	0.308
C34.0 Main bronchus	0.692	0.308
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.692	0.308
C43.9 Malignant melanoma of skin, unspecified	0.692	0.308
S00.0 Superficial injury of scalp	0.691	0.308
J60-J70 Lung diseases due to external agents	0.691	0.309
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.690	0.309
M13.96 Arthritis, unspecified (Lower leg)	0.690	0.310
Z44 Fitting and adjustment of external prosthetic device	0.689	0.311
M23.6 Other spontaneous disruption of ligament(s) of knee	0.689	0.311
M48 Other spondylopathies	0.689	0.311
C43.3 Malignant melanoma of other and unspecified parts of face	0.688	0.312
I95-I99 Other and unspecified disorders of the circulatory system	0.687	0.313
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.687	0.313
I05-I09 Chronic rheumatic heart diseases	0.687	0.313
T33-T35 Frostbite	0.686	0.313
T26-T28 Burns and corrosions confined to eye and internal organs	0.686	0.313
T20-T25 Burns and corrosions of external body surface, specified by site	0.686	0.313
T15-T19 Effects of foreign body entering through natural orifice	0.686	0.313
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.686	0.313
T00-T07 Injuries involving multiple body regions	0.686	0.313
S10-S19 Injuries to the neck	0.686	0.313
N13.3 Other and unspecified hydronephrosis	0.686	0.314
Q38-Q45 Other congenital malformations of the digestive system	0.685	0.315
Z47 Other orthopaedic follow-up care	0.684	0.316
Z46.9 Fitting and adjustment of other unspecified device	0.684	0.316
Z46.8 Fitting and adjustment of other specified devices	0.684	0.316
Z46.7 Fitting and adjustment of orthopaedic device	0.684	0.316
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.684	0.316
Z46.4 Fitting and adjustment of orthodontic device	0.684	0.316
Z46.3 Fitting and adjustment of dental prosthetic device	0.684	0.316
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.684	0.316
Z46.1 Fitting and adjustment of hearing aid	0.684	0.316
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.684	0.316
J17 Pneumonia in diseases classified elsewhere	0.684	0.316
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.684	0.316
J15 Bacterial pneumonia, not elsewhere classified	0.684	0.316
J12 Viral pneumonia, not elsewhere classified	0.684	0.316
J11 Influenza, virus not identified	0.684	0.316
J10 Influenza due to identified influenza virus	0.684	0.316
J13 Pneumonia due to Streptococcus pneumoniae	0.684	0.316
J09 Influenza due to certain identified influenza virus	0.684	0.316
S70-S79 Injuries to the hip and thigh	0.684	0.316
Q21 Congenital malformations of cardiac septa	0.683	0.317
D55-D59 Haemolytic anaemias	0.683	0.317
S00.1 Contusion of eyelid and periocular area	0.682	0.317
D63.0 Anaemia in neoplastic disease	0.681	0.319
Z95.0 Presence of cardiac pacemaker	0.681	0.319
O02 Other abnormal products of conception	0.680	0.320
M23.4 Loose body in knee	0.679	0.321
C18 Malignant neoplasm of colon	0.678	0.322
J40-J47 Chronic lower respiratory diseases	0.675	0.325
O62 Abnormalities of forces of labour	0.674	0.325
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.674	0.326
F17.9 Unspecified mental and behavioural disorder	0.674	0.326
F17.8 Other mental and behavioural disorders	0.674	0.326
F17.7 Residual and late-onset psychotic disorder	0.674	0.326
F17.6 Amnesic syndrome	0.674	0.326
F17.5 Psychotic disorder	0.674	0.326
F17.4 Withdrawal state with delirium	0.674	0.326
F17.3 Withdrawal state	0.674	0.326
F17.0 Acute intoxication	0.674	0.326
Q00-Q07 Congenital malformations of the nervous system	0.674	0.326
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.673	0.327
H65 Nonsuppurative otitis media	0.673	0.327
J90-J94 Other diseases of pleura	0.673	0.327
O34 Maternal care for known or suspected abnormality of pelvic organs	0.672	0.328
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.671	0.329
N15 Other renal tubulo-interstitial diseases	0.671	0.329
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.671	0.329
N11 Chronic tubulo-interstitial nephritis	0.671	0.329
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.670	0.330
M65 Synovitis and tenosynovitis	0.670	0.330
M20.0 Deformity of finger(s)	0.669	0.331
M25.8 Other specified joint disorders	0.668	0.331
V40-V49 Car occupant injured in transport accident	0.668	0.332
N00-N08 Glomerular diseases	0.668	0.332
S80-S89 Injuries to the knee and lower leg	0.667	0.333
O43 Placental disorders	0.666	0.334
E21.3 Hyperparathyroidism, unspecified	0.666	0.334
N17.9 Acute renal failure, unspecified	0.666	0.334
M35 Other systemic involvement of connective tissue	0.666	0.334
E22.0 Acromegaly and pituitary gigantism	0.665	0.335
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.665	0.335
S08 Traumatic amputation of part of head	0.663	0.336
S07 Crushing injury of head	0.663	0.336
S05 Injury of eye and orbit	0.663	0.336
S04 Injury of cranial nerves	0.663	0.336
S03 Dislocation, sprain and strain of joints and ligaments of head	0.663	0.336
E00-E07 Disorders of thyroid gland	0.663	0.337
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.663	0.337
C44.8 Overlapping lesion of skin	0.662	0.338
F30-F39 Mood [affective] disorders	0.661	0.338
S60-S69 Injuries to the wrist and hand	0.661	0.338
Z89.4 Acquired absence of foot and ankle	0.661	0.339
E35 Disorders of endocrine glands in diseases classified elsewhere	0.661	0.339
E34 Other endocrine disorders	0.661	0.339
E32 Diseases of thymus	0.661	0.339
E31 Polyglandular dysfunction	0.661	0.339
E30 Disorders of puberty, not elsewhere classified	0.661	0.339
E29 Testicular dysfunction	0.661	0.339
E27 Other disorders of adrenal gland	0.661	0.339
E26 Hyperaldosteronism	0.661	0.339
E25 Adrenogenital disorders	0.661	0.339
E24 Cushing's syndrome	0.661	0.339
E20 Hypoparathyroidism	0.661	0.339
O69.2 Labour and delivery complicated by other cord entanglement	0.660	0.340
N70-N77 Inflammatory diseases of female pelvic organs	0.660	0.340
Z92.1 Personal history of long-term (current) use of anticoagulants	0.659	0.341
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.659	0.341
F29 Unspecified nonorganic psychosis	0.659	0.341
I35.9 Aortic valve disorder, unspecified	0.659	0.341
H71 Cholesteatoma of middle ear	0.658	0.342
M13.93 Arthritis, unspecified (Forearm)	0.658	0.342
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.658	0.342
E21.0 Primary hyperparathyroidism	0.658	0.342
O36.6 Maternal care for excessive foetal growth	0.657	0.343
J21 Acute bronchiolitis	0.657	0.343
J20 Acute bronchitis	0.657	0.343
J86 Pyothorax	0.657	0.343
N18.4 Chronic kidney disease, stage 4	0.657	0.343
N20 Calculus of kidney and ureter	0.656	0.344
M40-M43 Deforming dorsopathies	0.656	0.344
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.656	0.344
E89.8 Other postprocedural endocrine and metabolic disorders	0.656	0.344
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.656	0.344
E89.5 Postprocedural testicular hypofunction	0.656	0.344
E89.4 Postprocedural ovarian failure	0.656	0.344
E89.2 Postprocedural hypoparathyroidism	0.656	0.344
E89.1 Postprocedural hypoinsulinaemia	0.656	0.344
E23 Hypofunction and other disorders of pituitary gland	0.655	0.344
M23.8 Other internal derangements of knee	0.655	0.345
M19.90 Arthrosis, unspecified (Multiple sites)	0.654	0.346
S09.9 Unspecified injury of head	0.654	0.346
M20.2 Hallux rigidus	0.654	0.346
V80-V89 Other land transport accidents	0.654	0.346
Z12.0 Special screening examination for neoplasm of stomach	0.653	0.347
N13.9 Obstructive and reflux uropathy, unspecified	0.652	0.348
N13.7 Vesicoureteral-reflux-associated uropathy	0.652	0.348
N13.6 Pyonephrosis	0.652	0.348
N13.4 Hydroureter	0.652	0.348
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.652	0.348
O42 Premature rupture of membranes	0.651	0.349
I45.1 Other and unspecified right bundle-branch block	0.650	0.350
C60-C63 Malignant neoplasms of male genital organs	0.650	0.350
C44.0 Skin of lip	0.649	0.351
J00-J06 Acute upper respiratory infections	0.649	0.351
J18.8 Other pneumonia, organism unspecified	0.648	0.352
J18.2 Hypostatic pneumonia, unspecified	0.648	0.352
J18.0 Bronchopneumonia, unspecified	0.648	0.352
E61 Deficiency of other nutrient elements	0.648	0.352
M14 Arthropathies in other diseases classified elsewhere	0.648	0.352
M12 Other specific arthropathies	0.648	0.352
M09 Juvenile arthritis in diseases classified elsewhere	0.648	0.352
M08 Juvenile arthritis	0.648	0.352
F00-F09 Organic, including symptomatic, mental disorders	0.647	0.353
M05 Seropositive rheumatoid arthritis	0.646	0.354
M67.8 Other specified disorders of synovium and tendon	0.645	0.355
E10 Insulin-dependent diabetes mellitus	0.645	0.355
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.644	0.356
M49 Spondylopathies in diseases classified elsewhere	0.643	0.356
M90 Osteopathies in diseases classified elsewhere	0.643	0.357
M25.9 Joint disorder, unspecified	0.643	0.357
M25.6 Stiffness of joint, not elsewhere classified	0.643	0.357
M25.3 Other instability of joint	0.643	0.357
M25.2 Flail joint	0.643	0.357
M25.1 Fistula of joint	0.643	0.357
M25.0 Haemarthrosis	0.643	0.357
I51.8 Other ill-defined heart diseases	0.642	0.358
Z93.2 Ileostomy status	0.641	0.359
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.641	0.359
A80-A89 Viral infections of the central nervous system	0.641	0.359
F52 Sexual dysfunction, not caused by organic disorder or disease	0.640	0.360
H73 Other disorders of tympanic membrane	0.640	0.360
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.639	0.360
Z43.2 Attention to ileostomy	0.639	0.361
Q60-Q64 Congenital malformations of the urinary system	0.639	0.361
I33 Acute and subacute endocarditis	0.639	0.361
I42 Cardiomyopathy	0.639	0.361
I44.2 Atrioventricular block, complete	0.639	0.361
C68 Malignant neoplasm of other and unspecified urinary organs	0.638	0.362
C66 Malignant neoplasm of ureter	0.638	0.362
C65 Malignant neoplasm of renal pelvis	0.638	0.362
I45.9 Conduction disorder, unspecified	0.638	0.362
M23.9 Internal derangement of knee, unspecified	0.638	0.362
M23.5 Chronic instability of knee	0.638	0.362
M23.1 Discoid meniscus (congenital)	0.638	0.362
M23.0 Cystic meniscus	0.638	0.362
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.636	0.364
Q80-Q89 Other congenital malformations	0.636	0.364
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.636	0.364
Q50-Q56 Congenital malformations of genital organs	0.636	0.364
Q35-Q37 Cleft lip and cleft palate	0.636	0.364
Q30-Q34 Congenital malformations of the respiratory system	0.636	0.364
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.636	0.364
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.636	0.364
B35-B49 Mycoses	0.636	0.364
C67 Malignant neoplasm of bladder	0.635	0.364
C43.8 Overlapping malignant melanoma of skin	0.635	0.365
C43.4 Malignant melanoma of scalp and neck	0.635	0.365
C43.2 Malignant melanoma of ear and external auricular canal	0.635	0.365
C43.1 Malignant melanoma of eyelid, including canthus	0.635	0.365
C43.0 Malignant melanoma of lip	0.635	0.365
S20-S29 Injuries to the thorax	0.634	0.366
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.634	0.366
O47 False labour	0.634	0.366
M19.94 Arthrosis, unspecified (Hand)	0.632	0.368
I31 Other diseases of pericardium	0.631	0.369
Z45.0 Adjustment and management of cardiac pacemaker	0.631	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations