TreeWAS – Variant ID: rs56276220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
R50-R69 General symptoms and signs	0.997	0.003
Chapter II Neoplasms	0.994	0.006
M05-M14 Inflammatory polyarthropathies	0.993	0.007
M70-M79 Other soft tissue disorders	0.989	0.011
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.980	0.020
M79 Other soft tissue disorders, not elsewhere classified	0.976	0.024
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.970	0.030
Chapter XII Diseases of the skin and subcutaneous tissue	0.968	0.032
K20-K31 Diseases of oesophagus, stomach and duodenum	0.967	0.033
M20-M25 Other joint disorders	0.966	0.034
K70-K77 Diseases of liver	0.962	0.038
T36-T50 Poisoning by drugs, medicaments and biological substances	0.962	0.038
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.960	0.040
K65-K67 Diseases of peritoneum	0.959	0.041
L00-L08 Infections of the skin and subcutaneous tissue	0.956	0.044
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.954	0.046
M79.8 Other specified soft tissue disorders	0.942	0.058
L03 Cellulitis	0.939	0.061
M15-M19 Arthrosis	0.936	0.064
S60-S69 Injuries to the wrist and hand	0.935	0.065
R93 Abnormal findings on diagnostic imaging of other body structures	0.931	0.069
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.930	0.070
M23 Internal derangement of knee	0.926	0.074
R63 Symptoms and signs concerning food and fluid intake	0.925	0.075
M06 Other rheumatoid arthritis	0.925	0.075
K30 Dyspepsia	0.924	0.076
Chapter IX Diseases of the circulatory system	0.924	0.076
R26 Abnormalities of gait and mobility	0.922	0.078
L03.1 Cellulitis of other parts of limb	0.921	0.079
K66 Other disorders of peritoneum	0.917	0.083
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.914	0.086
Chapter XX External causes of morbidity and mortality	0.909	0.091
S80-S89 Injuries to the knee and lower leg	0.909	0.091
K21 Gastro-oesophageal reflux disease	0.909	0.091
M13 Other arthritis	0.906	0.094
M17 Gonarthrosis [arthrosis of knee]	0.905	0.095
R51 Headache	0.902	0.098
I60-I69 Cerebrovascular diseases	0.901	0.099
M10 Gout	0.897	0.103
M25 Other joint disorders, not elsewhere classified	0.895	0.105
R59 Enlarged lymph nodes	0.892	0.108
M79.86 Other specified soft tissue disorders (Lower leg)	0.892	0.108
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.892	0.108
R26.8 Other and unspecified abnormalities of gait and mobility	0.889	0.111
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.884	0.116
K83 Other diseases of biliary tract	0.883	0.117
C50-C50 Malignant neoplasm of breast	0.880	0.120
M17.1 Other primary gonarthrosis	0.878	0.122
C51-C58 Malignant neoplasms of female genital organs	0.878	0.122
K66.0 Peritoneal adhesions	0.877	0.123
C78.7 Secondary malignant neoplasm of liver	0.874	0.126
K20 Oesophagitis	0.873	0.127
Chapter I Certain infectious and parasitic diseases	0.873	0.127
Chapter IV Endocrine, nutritional and metabolic diseases	0.873	0.127
C15-C26 Malignant neoplasms of digestive organs	0.871	0.129
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.870	0.130
R52 Pain, not elsewhere classified	0.866	0.134
M06.9 Rheumatoid arthritis, unspecified	0.861	0.139
K35-K38 Diseases of appendix	0.861	0.139
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.857	0.143
D37-D48 Neoplasms of uncertain or unknown behaviour	0.855	0.145
M72 Fibroblastic disorders	0.852	0.148
R91 Abnormal findings on diagnostic imaging of lung	0.851	0.149
M79.6 Pain in limb	0.850	0.150
S82 Fracture of lower leg, including ankle	0.849	0.151
R63.4 Abnormal weight loss	0.848	0.152
K80 Cholelithiasis	0.848	0.152
M13.9 Arthritis, unspecified	0.844	0.156
C64-C68 Malignant neoplasms of urinary tract	0.844	0.156
K72 Hepatic failure, not elsewhere classified	0.843	0.157
C79 Secondary malignant neoplasm of other sites	0.843	0.157
M65-M68 Disorders of synovium and tendon	0.840	0.160
Chapter XXII Codes for special purposes	0.839	0.161
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.837	0.163
M23.8 Other internal derangements of knee	0.837	0.163
M25.5 Pain in joint	0.837	0.163
B95-B98 Bacterial, viral and other infectious agents	0.834	0.166
L05 Pilonidal cyst	0.831	0.169
S00-S09 Injuries to the head	0.831	0.169
K83.8 Other specified diseases of biliary tract	0.831	0.169
R47-R49 Symptoms and signs involving speech and voice	0.830	0.170
T40.2 Other opioids	0.829	0.171
M10.9 Gout, unspecified	0.829	0.171
R55 Syncope and collapse	0.827	0.173
K90-K93 Other diseases of the digestive system	0.824	0.176
R56 Convulsions, not elsewhere classified	0.822	0.178
Chapter X Diseases of the respiratory system	0.820	0.180
I80 Phlebitis and thrombophlebitis	0.819	0.181
D70-D77 Other diseases of blood and blood-forming organs	0.818	0.182
K76 Other diseases of liver	0.818	0.182
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.812	0.188
R90 Abnormal findings on diagnostic imaging of central nervous system	0.810	0.190
E70-E90 Metabolic disorders	0.810	0.190
M79.7 Fibromyalgia	0.803	0.197
I64 Stroke, not specified as haemorrhage or infarction	0.803	0.197
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.803	0.197
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.803	0.197
R50 Fever of unknown origin	0.802	0.198
Chapter V Mental and behavioural disorders	0.801	0.199
C50 Malignant neoplasm of breast	0.799	0.201
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.799	0.201
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.797	0.203
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.797	0.203
M21 Other acquired deformities of limbs	0.796	0.204
M91-M94 Chondropathies	0.795	0.205
M25.55 Pain in joint (Pelvic region and thigh)	0.793	0.207
L40-L45 Papulosquamous disorders	0.792	0.208
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.790	0.210
R59.1 Generalised enlarged lymph nodes	0.788	0.212
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.788	0.212
S90-S99 Injuries to the ankle and foot	0.787	0.213
M79.84 Other specified soft tissue disorders (Hand)	0.785	0.215
M45-M49 Spondylopathies	0.784	0.216
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.782	0.218
M07 Psoriatic and enteropathic arthropathies	0.780	0.220
K75 Other inflammatory liver diseases	0.776	0.224
M70 Soft tissue disorders related to use, overuse and pressure	0.776	0.224
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.775	0.225
M10.99 Gout, unspecified (Site unspecified)	0.774	0.226
R53 Malaise and fatigue	0.773	0.227
C19 Malignant neoplasm of rectosigmoid junction	0.772	0.228
D80-D89 Certain disorders involving the immune mechanism	0.772	0.228
K65 Peritonitis	0.770	0.230
I63 Cerebral infarction	0.769	0.231
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.766	0.234
M23.3 Other meniscus derangements	0.765	0.234
M80-M85 Disorders of bone density and structure	0.765	0.235
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.765	0.235
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.764	0.235
Chapter VIII Diseases of the ear and mastoid process	0.761	0.239
L50-L54 Urticaria and erythema	0.760	0.240
C78.0 Secondary malignant neoplasm of lung	0.759	0.241
S70-S79 Injuries to the hip and thigh	0.759	0.241
K72.9 Hepatic failure, unspecified	0.758	0.242
M23.0 Cystic meniscus	0.758	0.242
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.757	0.243
K74 Fibrosis and cirrhosis of liver	0.756	0.244
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.756	0.244
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.756	0.244
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.755	0.245
S82.3 Fracture of lower end of tibia	0.754	0.246
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.754	0.246
S10-S19 Injuries to the neck	0.751	0.249
R63.0 Anorexia	0.750	0.250
L03.9 Cellulitis, unspecified	0.750	0.250
C50.9 Breast, unspecified	0.749	0.251
R61 Hyperhidrosis	0.749	0.251
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.749	0.251
D00-D09 In situ neoplasms	0.749	0.251
S62 Fracture at wrist and hand level	0.748	0.252
K27 Peptic ulcer, site unspecified	0.748	0.252
T66-T78 Other and unspecified effects of external causes	0.747	0.253
R26.0 Ataxic gait	0.747	0.253
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.744	0.256
M79.5 Residual foreign body in soft tissue	0.744	0.256
R27 Other lack of coordination	0.744	0.256
J90-J94 Other diseases of pleura	0.744	0.256
D60-D64 Aplastic and other anaemias	0.744	0.256
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.743	0.256
I86 Varicose veins of other sites	0.743	0.257
J95-J99 Other diseases of the respiratory system	0.742	0.258
T39.1 4-Aminophenol derivatives	0.742	0.258
K70 Alcoholic liver disease	0.742	0.258
C80 Malignant neoplasm without specification of site	0.741	0.259
M11 Other crystal arthropathies	0.741	0.259
S68 Traumatic amputation of wrist and hand	0.740	0.260
R68 Other general symptoms and signs	0.739	0.261
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.739	0.261
L03.8 Cellulitis of other sites	0.739	0.261
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.739	0.261
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.738	0.262
E86 Volume depletion	0.738	0.262
R52.0 Acute pain	0.738	0.262
M65 Synovitis and tenosynovitis	0.737	0.263
M79.65 Pain in limb (Pelvic region and thigh)	0.735	0.265
M19 Other arthrosis	0.734	0.266
K80.0 Calculus of gallbladder with acute cholecystitis	0.734	0.266
L05.9 Pilonidal cyst without abscess	0.732	0.268
S82.6 Fracture of lateral malleolus	0.732	0.268
S50-S59 Injuries to the elbow and forearm	0.732	0.268
W20-W49 Exposure to inanimate mechanical forces	0.732	0.268
C18 Malignant neoplasm of colon	0.731	0.269
M13.99 Arthritis, unspecified (Site unspecified)	0.730	0.270
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.730	0.270
E50-E64 Other nutritional deficiencies	0.729	0.271
M23.4 Loose body in knee	0.729	0.271
I69 Sequelae of cerebrovascular disease	0.729	0.271
S61 Open wound of wrist and hand	0.728	0.272
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.728	0.272
K35 Acute appendicitis	0.728	0.272
E65-E68 Obesity and other hyperalimentation	0.727	0.273
K66.8 Other specified disorders of peritoneum	0.727	0.273
M06.0 Seronegative rheumatoid arthritis	0.727	0.273
R49 Voice disturbances	0.725	0.275
M40-M43 Deforming dorsopathies	0.725	0.275
K81 Cholecystitis	0.722	0.278
I67 Other cerebrovascular diseases	0.722	0.278
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.720	0.280
E87 Other disorders of fluid, electrolyte and acid-base balance	0.719	0.281
M79.89 Other specified soft tissue disorders (Site unspecified)	0.719	0.281
M86-M90 Other osteopathies	0.718	0.282
K50-K52 Noninfective enteritis and colitis	0.717	0.282
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
S60 Superficial injury of wrist and hand	0.717	0.283
T79-T79 Certain early complications of trauma	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
M25.51 Pain in joint (Shoulder region)	0.716	0.284
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.284
M05 Seropositive rheumatoid arthritis	0.715	0.285
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.715	0.285
R62 Lack of expected normal physiological development	0.715	0.285
R57 Shock, not elsewhere classified	0.715	0.285
R64 Cachexia	0.715	0.285
R58 Haemorrhage, not elsewhere classified	0.715	0.285
M13.90 Arthritis, unspecified (Multiple sites)	0.713	0.287
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.713	0.287
K86 Other diseases of pancreas	0.713	0.287
M14 Arthropathies in other diseases classified elsewhere	0.712	0.288
M12 Other specific arthropathies	0.712	0.288
M09 Juvenile arthritis in diseases classified elsewhere	0.712	0.288
M08 Juvenile arthritis	0.712	0.288
C54 Malignant neoplasm of corpus uteri	0.712	0.288
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.711	0.289
S40-S49 Injuries to the shoulder and upper arm	0.710	0.290
M22 Disorders of patella	0.709	0.291
M77 Other enthesopathies	0.709	0.291
M76 Enthesopathies of lower limb, excluding foot	0.709	0.291
M73 Soft tissue disorders in diseases classified elsewhere	0.709	0.291
M71 Other bursopathies	0.709	0.291
C79.8 Secondary malignant neoplasm of other specified sites	0.709	0.291
K85 Acute pancreatitis	0.708	0.292
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.708	0.292
S64 Injury of nerves at wrist and hand level	0.707	0.293
D70 Agranulocytosis	0.706	0.294
K80.2 Calculus of gallbladder without cholecystitis	0.706	0.294
M17.0 Primary gonarthrosis, bilateral	0.705	0.295
C64 Malignant neoplasm of kidney, except renal pelvis	0.704	0.296
I85 Oesophageal varices	0.704	0.296
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.703	0.296
R92 Abnormal findings on diagnostic imaging of breast	0.702	0.297
X60-X84 Intentional self-harm	0.702	0.298
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.701	0.299
M79.9 Soft tissue disorder, unspecified	0.700	0.300
M79.4 Hypertrophy of (infrapatellar) fat pad	0.700	0.300
M79.3 Panniculitis, unspecified	0.700	0.300
M79.2 Neuralgia and neuritis, unspecified	0.700	0.300
M79.1 Myalgia	0.700	0.300
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.700	0.300
C51 Malignant neoplasm of vulva	0.699	0.301
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.699	0.301
L03.0 Cellulitis of finger and toe	0.698	0.302
R54 Senility	0.698	0.302
R59.9 Enlarged lymph nodes, unspecified	0.696	0.304
R56.8 Other and unspecified convulsions	0.696	0.304
C76 Malignant neoplasm of other and ill-defined sites	0.695	0.305
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.695	0.305
R60 Oedema, not elsewhere classified	0.695	0.305
I05-I09 Chronic rheumatic heart diseases	0.694	0.306
L10-L14 Bullous disorders	0.694	0.306
M79.64 Pain in limb (Hand)	0.694	0.306
V80-V89 Other land transport accidents	0.693	0.307
K28 Gastrojejunal ulcer	0.693	0.307
K23 Disorders of oesophagus in diseases classified elsewhere	0.693	0.307
R52.1 Chronic intractable pain	0.693	0.307
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.693	0.307
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.693	0.307
M34 Systemic sclerosis	0.693	0.307
M33 Dermatopolymyositis	0.693	0.307
M32 Systemic lupus erythematosus	0.693	0.307
M30 Polyarteritis nodosa and related conditions	0.693	0.307
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.692	0.307
R94 Abnormal results of function studies	0.692	0.308
R41 Other symptoms and signs involving cognitive functions and awareness	0.691	0.309
L02 Cutaneous abscess, furuncle and carbuncle	0.690	0.309
K77 Liver disorders in diseases classified elsewhere	0.690	0.310
K73 Chronic hepatitis, not elsewhere classified	0.690	0.310
K71 Toxic liver disease	0.690	0.310
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.690	0.310
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.690	0.310
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.690	0.310
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.690	0.310
T46 Poisoning by agents primarily affecting the cardiovascular system	0.690	0.310
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.690	0.310
T41 Poisoning by anaesthetics and therapeutic gases	0.690	0.310
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.690	0.310
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.690	0.310
T36 Poisoning by systemic antibiotics	0.690	0.310
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.689	0.311
C56 Malignant neoplasm of ovary	0.689	0.311
Y43 Primarily systemic agents	0.689	0.311
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.688	0.312
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.688	0.312
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.688	0.312
V10-V19 Pedal cyclist injured in transport accident	0.688	0.312
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.687	0.313
J98 Other respiratory disorders	0.686	0.314
S82.30 Fracture of lower end of tibia (closed)	0.686	0.314
L04 Acute lymphadenitis	0.686	0.314
L01 Impetigo	0.686	0.314
L00 Staphylococcal scalded skin syndrome	0.686	0.314
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.684	0.316
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.684	0.316
S01 Open wound of head	0.683	0.317
M18 Arthrosis of first carpometacarpal joint	0.682	0.318
R03 Abnormal blood-pressure reading, without diagnosis	0.682	0.318
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.682	0.318
D72 Other disorders of white blood cells	0.680	0.320
R18 Ascites	0.680	0.320
M79.79 Fibromyalgia (Site unspecified)	0.680	0.320
D62 Acute posthaemorrhagic anaemia	0.679	0.321
K37 Unspecified appendicitis	0.678	0.322
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.678	0.322
T92 Sequelae of injuries of upper limb	0.677	0.323
M79.88 Other specified soft tissue disorders (Other)	0.676	0.324
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.676	0.324
M79.83 Other specified soft tissue disorders (Forearm)	0.676	0.324
M79.82 Other specified soft tissue disorders (Upper arm)	0.676	0.324
M79.81 Other specified soft tissue disorders (Shoulder region)	0.676	0.324
M79.80 Other specified soft tissue disorders (Multiple sites)	0.676	0.324
I87 Other disorders of veins	0.675	0.325
R14 Flatulence and related conditions	0.675	0.325
S20-S29 Injuries to the thorax	0.675	0.325
K92 Other diseases of digestive system	0.675	0.325
M21.3 Wrist or foot drop (acquired)	0.674	0.326
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.672	0.328
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.671	0.329
R52.9 Pain, unspecified	0.671	0.329
M15 Polyarthrosis	0.671	0.329
S69 Other and unspecified injuries of wrist and hand	0.671	0.329
S67 Crushing injury of wrist and hand	0.671	0.329
S65 Injury of blood vessels at wrist and hand level	0.671	0.329
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.671	0.329
L08 Other local infections of skin and subcutaneous tissue	0.670	0.330
M13.97 Arthritis, unspecified (Ankle and foot)	0.669	0.331
I81 Portal vein thrombosis	0.669	0.331
R25 Abnormal involuntary movements	0.669	0.331
V20-V29 Motorcycle rider injured in transport accident	0.668	0.332
T39.0 Salicylates	0.668	0.332
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.668	0.332
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.667	0.333
R93.6 Abnormal findings on diagnostic imaging of limbs	0.667	0.333
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.667	0.333
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.667	0.333
D55-D59 Haemolytic anaemias	0.666	0.333
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.666	0.334
C71 Malignant neoplasm of brain	0.666	0.334
K76.8 Other specified diseases of liver	0.666	0.334
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.666	0.334
T93 Sequelae of injuries of lower limb	0.665	0.334
R11 Nausea and vomiting	0.665	0.335
A50-A64 Infections with a predominantly sexual mode of transmission	0.665	0.335
M79.0 Rheumatism, unspecified	0.664	0.336
K80.1 Calculus of gallbladder with other cholecystitis	0.664	0.336
D86 Sarcoidosis	0.664	0.336
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.664	0.336
M23.9 Internal derangement of knee, unspecified	0.664	0.336
M23.6 Other spontaneous disruption of ligament(s) of knee	0.664	0.336
M23.5 Chronic instability of knee	0.664	0.336
M23.1 Discoid meniscus (congenital)	0.664	0.336
R63.8 Other symptoms and signs concerning food and fluid intake	0.663	0.336
R63.6 Insufficient intake of food and water due to self neglect	0.663	0.336
R63.5 Abnormal weight gain	0.663	0.336
R63.3 Feeding difficulties and mismanagement	0.663	0.336
R63.2 Polyphagia	0.663	0.336
R63.1 Polydipsia	0.663	0.336
S66 Injury of muscle and tendon at wrist and hand level	0.663	0.336
M06.8 Other specified rheumatoid arthritis	0.663	0.337
M06.4 Inflammatory polyarthropathy	0.663	0.337
M06.3 Rheumatoid nodule	0.663	0.337
M06.2 Rheumatoid bursitis	0.663	0.337
M06.1 Adult-onset Still's disease	0.663	0.337
I00-I02 Acute rheumatic fever	0.662	0.338
M25.7 Osteophyte	0.662	0.338
M25.54 Pain in joint (Hand)	0.662	0.338
R26.3 Immobility	0.661	0.339
R26.2 Difficulty in walking, not elsewhere classified	0.661	0.339
R26.1 Paralytic gait	0.661	0.339
C50.3 Lower-inner quadrant of breast	0.661	0.339
C67 Malignant neoplasm of bladder	0.660	0.340
R09.1 Pleurisy	0.659	0.341
D45 Polycythaemia vera	0.659	0.341
M48 Other spondylopathies	0.659	0.341
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.659	0.341
R59.0 Localised enlarged lymph nodes	0.658	0.342
K66.9 Disorder of peritoneum, unspecified	0.658	0.342
K66.1 Haemoperitoneum	0.658	0.342
L43 Lichen planus	0.658	0.342
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.656	0.344
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.655	0.345
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.655	0.345
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.655	0.345
C78.4 Secondary malignant neoplasm of small intestine	0.655	0.345
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.655	0.345
C78.1 Secondary malignant neoplasm of mediastinum	0.655	0.345
I80.8 Phlebitis and thrombophlebitis of other sites	0.655	0.345
C53 Malignant neoplasm of cervix uteri	0.654	0.346
E83 Disorders of mineral metabolism	0.654	0.346
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.652	0.348
Y35-Y36 Legal intervention and operations of war	0.652	0.348
Y10-Y34 Event of undetermined intent	0.652	0.348
Y00-Y09 Assault	0.652	0.348
X85-X99 Assault	0.652	0.348
X58-X59 Accidental exposure to other and unspecified factors	0.652	0.348
X50-X57 Overexertion, travel and privation	0.652	0.348
X40-X49 Accidental poisoning by and exposure to noxious substances	0.652	0.348
X30-X39 Exposure to forces of nature	0.652	0.348
X20-X29 Contact with venomous animals and plants	0.652	0.348
X10-X19 Contact with heat and hot substances	0.652	0.348
X00-X09 Exposure to smoke, fire and flames	0.652	0.348
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.652	0.348
W75-W84 Other accidental threats to breathing	0.652	0.348
W65-W74 Accidental drowning and submersion	0.652	0.348
W50-W64 Exposure to animate mechanical forces	0.652	0.348
V98-V99 Other and unspecified transport accidents	0.652	0.348
V95-V97 Air and space transport accidents	0.652	0.348
V90-V94 Water transport accidents	0.652	0.348
V70-V79 Bus occupant injured in transport accident	0.652	0.348
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.652	0.348
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.652	0.348
V40-V49 Car occupant injured in transport accident	0.652	0.348
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.652	0.348
V01-V09 Pedestrian injured in transport accident	0.652	0.348
M13.98 Arthritis, unspecified (Other)	0.652	0.348
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.652	0.348
M25.4 Effusion of joint	0.652	0.348
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.651	0.348
S89 Other and unspecified injuries of lower leg	0.651	0.348
S88 Traumatic amputation of lower leg	0.651	0.348
S87 Crushing injury of lower leg	0.651	0.348
S86 Injury of muscle and tendon at lower leg level	0.651	0.348
S85 Injury of blood vessels at lower leg level	0.651	0.348
S84 Injury of nerves at lower leg level	0.651	0.348
S81 Open wound of lower leg	0.651	0.348
Chapter XXI Factors influencing health status and contact with health services	0.651	0.349
I62 Other nontraumatic intracranial haemorrhage	0.651	0.349
R49.0 Dysphonia	0.651	0.349
S82.8 Fractures of other parts of lower leg	0.651	0.349
J40-J47 Chronic lower respiratory diseases	0.650	0.350
M13.8 Other specified arthritis	0.650	0.350
M13.1 Monoarthritis, not elsewhere classified	0.650	0.350
M13.0 Polyarthritis, unspecified	0.650	0.350
M65.9 Synovitis and tenosynovitis, unspecified	0.650	0.350
M17.5 Other secondary gonarthrosis	0.649	0.351
M17.4 Other secondary gonarthrosis, bilateral	0.649	0.351
M17.3 Other posttraumatic gonarthrosis	0.649	0.351
M17.2 Posttraumatic gonarthrosis, bilateral	0.649	0.351
S82.60 Fracture of lateral malleolus (closed)	0.649	0.351
S02 Fracture of skull and facial bones	0.648	0.352
K83.0 Cholangitis	0.648	0.352
M94 Other disorders of cartilage	0.648	0.352
I68 Cerebrovascular disorders in diseases classified elsewhere	0.646	0.354
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.646	0.354
I60 Subarachnoid haemorrhage	0.646	0.354
I70-I79 Diseases of arteries, arterioles and capillaries	0.646	0.354
C77.3 Axillary and upper limb lymph nodes	0.646	0.354
K29 Gastritis and duodenitis	0.644	0.356
M10.4 Other secondary gout	0.643	0.357
M10.3 Gout due to impairment of renal function	0.643	0.357
M10.2 Drug-induced gout	0.643	0.357
M10.1 Lead-induced gout	0.643	0.357
M10.0 Idiopathic gout	0.643	0.357
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.643	0.357
L20-L30 Dermatitis and eczema	0.643	0.357
K76.9 Liver disease, unspecified	0.643	0.357
K75.9 Inflammatory liver disease, unspecified	0.642	0.358
M25.9 Joint disorder, unspecified	0.641	0.358
M25.8 Other specified joint disorders	0.641	0.358
M25.6 Stiffness of joint, not elsewhere classified	0.641	0.358
M25.3 Other instability of joint	0.641	0.358
M25.2 Flail joint	0.641	0.358
M25.1 Fistula of joint	0.641	0.358
M25.0 Haemarthrosis	0.641	0.358
R40 Somnolence, stupor and coma	0.641	0.359
M23.2 Derangement of meniscus due to old tear or injury	0.641	0.359
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.640	0.360
J92 Pleural plaque	0.640	0.360
M79.67 Pain in limb (Ankle and foot)	0.638	0.362
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.637	0.363
C79.7 Secondary malignant neoplasm of adrenal gland	0.637	0.363
S80 Superficial injury of lower leg	0.637	0.363
M13.94 Arthritis, unspecified (Hand)	0.636	0.364
R04 Haemorrhage from respiratory passages	0.636	0.364
S92 Fracture of foot, except ankle	0.634	0.366
Y60-Y69 Misadventures to patients during surgical and medical care	0.634	0.366

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations