TreeWAS – Variant ID: rs7190458

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.003	0.997
I20-I25 Ischaemic heart diseases	0.000	0.003	0.997
I25.1 Atherosclerotic heart disease	0.000	0.007	0.993
I21 Acute myocardial infarction	0.000	0.010	0.990
I21.9 Acute myocardial infarction, unspecified	0.000	0.012	0.988
I20 Angina pectoris	0.000	0.017	0.983
I20.9 Angina pectoris, unspecified	0.000	0.025	0.975
# Top node	0.974	0.026	0.000
Chapter II Neoplasms	0.973	0.027	0.000
Chapter V Mental and behavioural disorders	0.972	0.028	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.968	0.032	0.000
I25.2 Old myocardial infarction	0.000	0.035	0.965
C64-C68 Malignant neoplasms of urinary tract	0.965	0.035	0.000
C67 Malignant neoplasm of bladder	0.962	0.038	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.960	0.040	0.000
C15-C26 Malignant neoplasms of digestive organs	0.960	0.040	0.000
F41 Other anxiety disorders	0.959	0.041	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.952	0.048	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.946	0.054	0.000
F41.9 Anxiety disorder, unspecified	0.945	0.055	0.000
C25 Malignant neoplasm of pancreas	0.943	0.057	0.000
Chapter XI Diseases of the digestive system	0.932	0.068	0.000
C67.9 Bladder, unspecified	0.931	0.069	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.929	0.071	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.073	0.927
K81 Cholecystitis	0.918	0.082	0.000
C51-C58 Malignant neoplasms of female genital organs	0.917	0.083	0.000
L40 Psoriasis	0.915	0.085	0.000
C25.9 Pancreas, unspecified	0.914	0.086	0.000
L40-L45 Papulosquamous disorders	0.913	0.087	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.912	0.088	0.000
L40.9 Psoriasis, unspecified	0.909	0.091	0.000
F43 Reaction to severe stress, and adjustment disorders	0.906	0.094	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.906	0.094	0.000
I24 Other acute ischaemic heart diseases	0.000	0.097	0.903
K83 Other diseases of biliary tract	0.895	0.105	0.000
C18 Malignant neoplasm of colon	0.891	0.109	0.000
K81.1 Chronic cholecystitis	0.889	0.111	0.000
L40.5 Arthropathic psoriasis	0.879	0.121	0.000
F60-F69 Disorders of adult personality and behaviour	0.873	0.127	0.000
K81.9 Cholecystitis, unspecified	0.872	0.128	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.865	0.135	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.857	0.143	0.000
C67.8 Overlapping lesion of bladder	0.852	0.148	0.000
F99-F99 Unspecified mental disorder	0.851	0.149	0.000
Chapter VI Diseases of the nervous system	0.850	0.150	0.000
K83.0 Cholangitis	0.849	0.151	0.000
Chapter XX External causes of morbidity and mortality	0.847	0.153	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.846	0.154	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.846	0.154	0.000
F41.2 Mixed anxiety and depressive disorder	0.844	0.156	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.165	0.835
C53 Malignant neoplasm of cervix uteri	0.834	0.166	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.834	0.166	0.000
C18.2 Ascending colon	0.833	0.167	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.823	0.177	0.000
T92 Sequelae of injuries of upper limb	0.821	0.179	0.000
F43.9 Reaction to severe stress, unspecified	0.820	0.180	0.000
S70-S79 Injuries to the hip and thigh	0.818	0.182	0.000
C17 Malignant neoplasm of small intestine	0.817	0.182	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.817	0.183	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.184	0.816
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.816	0.184	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.815	0.185	0.000
C25.0 Head of pancreas	0.814	0.186	0.000
C54 Malignant neoplasm of corpus uteri	0.814	0.186	0.000
C67.6 Ureteric orifice	0.811	0.189	0.000
K86 Other diseases of pancreas	0.810	0.190	0.000
C18.4 Transverse colon	0.809	0.191	0.000
C67.4 Posterior wall of bladder	0.809	0.191	0.000
I20.8 Other forms of angina pectoris	0.000	0.192	0.808
K40-K46 Hernia	0.804	0.196	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.802	0.198	0.000
F60 Specific personality disorders	0.802	0.198	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.800	0.200	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.798	0.202	0.000
S00-S09 Injuries to the head	0.797	0.203	0.000
T93 Sequelae of injuries of lower limb	0.789	0.211	0.000
Q00-Q07 Congenital malformations of the nervous system	0.789	0.211	0.000
K85 Acute pancreatitis	0.788	0.212	0.000
C67.2 Lateral wall of bladder	0.783	0.217	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.777	0.223	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.776	0.224	0.000
C53.9 Cervix uteri, unspecified	0.775	0.225	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.773	0.227	0.000
F41.1 Generalised anxiety disorder	0.771	0.229	0.000
K13 Other diseases of lip and oral mucosa	0.771	0.229	0.000
S00 Superficial injury of head	0.770	0.230	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.768	0.232	0.000
C23 Malignant neoplasm of gallbladder	0.768	0.232	0.000
T92.1 Sequelae of fracture of arm	0.766	0.234	0.000
F99 Mental disorder, not otherwise specified	0.764	0.236	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.761	0.239	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.758	0.242	0.000
K35-K38 Diseases of appendix	0.758	0.242	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.757	0.243	0.000
F48 Other neurotic disorders	0.757	0.243	0.000
K83.8 Other specified diseases of biliary tract	0.757	0.243	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.755	0.245	0.000
S20-S29 Injuries to the thorax	0.749	0.250	0.000
C34 Malignant neoplasm of bronchus and lung	0.748	0.252	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.747	0.253	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.746	0.254	0.000
C18.5 Splenic flexure	0.744	0.256	0.000
F43.1 Posttraumatic stress disorder	0.743	0.257	0.000
C67.3 Anterior wall of bladder	0.742	0.258	0.000
C66 Malignant neoplasm of ureter	0.741	0.259	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.741	0.259	0.000
C54.1 Endometrium	0.740	0.260	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.740	0.260	0.000
Q60-Q64 Congenital malformations of the urinary system	0.739	0.261	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.739	0.261	0.000
F80-F89 Disorders of psychological development	0.737	0.263	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.265	0.735
L10-L14 Bullous disorders	0.733	0.267	0.000
K41 Femoral hernia	0.732	0.268	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.732	0.268	0.000
G37 Other demyelinating diseases of central nervous system	0.731	0.269	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.730	0.270	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.729	0.271	0.000
F43.2 Adjustment disorders	0.726	0.274	0.000
S70 Superficial injury of hip and thigh	0.725	0.275	0.000
S00.9 Superficial injury of head, part unspecified	0.725	0.275	0.000
S60-S69 Injuries to the wrist and hand	0.722	0.278	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.721	0.279	0.000
Y86 Sequelae of other accidents	0.721	0.279	0.000
K14 Diseases of tongue	0.721	0.279	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.720	0.280	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.281	0.719
T46 Poisoning by agents primarily affecting the cardiovascular system	0.718	0.282	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.284	0.716
I25.6 Silent myocardial ischaemia	0.000	0.285	0.715
I25.4 Coronary artery aneurysm	0.000	0.285	0.715
I25.3 Aneurysm of heart	0.000	0.285	0.715
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.285	0.715
I23 Certain current complications following acute myocardial infarction	0.000	0.285	0.715
C21 Malignant neoplasm of anus and anal canal	0.712	0.288	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.290	0.710
L43 Lichen planus	0.709	0.291	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.709	0.291	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.704	0.295	0.000
C25.2 Tail of pancreas	0.704	0.296	0.000
S00.1 Contusion of eyelid and periocular area	0.702	0.298	0.000
Q50-Q56 Congenital malformations of genital organs	0.701	0.299	0.000
Q43 Other congenital malformations of intestine	0.699	0.301	0.000
W20-W49 Exposure to inanimate mechanical forces	0.699	0.301	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.698	0.301	0.000
S50-S59 Injuries to the elbow and forearm	0.699	0.301	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.698	0.302	0.000
G40-G47 Episodic and paroxysmal disorders	0.697	0.303	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.697	0.303	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.697	0.303	0.000
F70-F79 Mental retardation	0.697	0.303	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.696	0.304	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.696	0.304	0.000
K86.8 Other specified diseases of pancreas	0.695	0.305	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.695	0.305	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.694	0.306	0.000
F44 Dissociative [conversion] disorders	0.694	0.306	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.692	0.308	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.692	0.308	0.000
O60-O75 Complications of labour and delivery	0.691	0.309	0.000
V40-V49 Car occupant injured in transport accident	0.690	0.310	0.000
C67.7 Urachus	0.689	0.311	0.000
C67.0 Trigone of bladder	0.689	0.311	0.000
T33-T35 Frostbite	0.688	0.312	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.688	0.312	0.000
T00-T07 Injuries involving multiple body regions	0.688	0.312	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.688	0.312	0.000
F41.8 Other specified anxiety disorders	0.688	0.312	0.000
F41.3 Other mixed anxiety disorders	0.688	0.312	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.688	0.312	0.000
Q80-Q89 Other congenital malformations	0.687	0.313	0.000
Q21 Congenital malformations of cardiac septa	0.686	0.314	0.000
C65 Malignant neoplasm of renal pelvis	0.683	0.317	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.317	0.683
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.682	0.318	0.000
Q35-Q37 Cleft lip and cleft palate	0.682	0.318	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.682	0.318	0.000
T42.1 Iminostilbenes	0.682	0.318	0.000
K43 Ventral hernia	0.682	0.318	0.000
K83.9 Disease of biliary tract, unspecified	0.681	0.318	0.000
F20 Schizophrenia	0.681	0.319	0.000
E11.9 Without complications	0.000	0.319	0.681
F42 Obsessive-compulsive disorder	0.681	0.319	0.000
O23 Infections of genito-urinary tract in pregnancy	0.679	0.320	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.679	0.321	0.000
C18.6 Descending colon	0.678	0.322	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.678	0.322	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.678	0.322	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.678	0.322	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.678	0.322	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.678	0.322	0.000
T36 Poisoning by systemic antibiotics	0.678	0.322	0.000
C25.8 Overlapping lesion of pancreas	0.676	0.324	0.000
C25.7 Other parts of pancreas	0.676	0.324	0.000
C25.4 Endocrine pancreas	0.676	0.324	0.000
C25.3 Pancreatic duct	0.676	0.324	0.000
C25.1 Body of pancreas	0.676	0.324	0.000
T98 Sequelae of other and unspecified effects of external causes	0.676	0.324	0.000
K85.2 Alcohol-induced acute pancreatitis	0.673	0.327	0.000
C34.9 Bronchus or lung, unspecified	0.673	0.327	0.000
C32 Malignant neoplasm of larynx	0.672	0.328	0.000
C07 Malignant neoplasm of parotid gland	0.670	0.330	0.000
F60.7 Dependent personality disorder	0.669	0.331	0.000
Q05 Spina bifida	0.668	0.332	0.000
K37 Unspecified appendicitis	0.668	0.332	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.667	0.333	0.000
X10-X19 Contact with heat and hot substances	0.667	0.333	0.000
K46 Unspecified abdominal hernia	0.666	0.334	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.666	0.334	0.000
I22 Subsequent myocardial infarction	0.000	0.335	0.665
C17.0 Duodenum	0.663	0.336	0.000
F60.9 Personality disorder, unspecified	0.662	0.338	0.000
K38 Other diseases of appendix	0.662	0.338	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.661	0.339	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.660	0.340	0.000
K10 Other diseases of jaws	0.660	0.340	0.000
F60.3 Emotionally unstable personality disorder	0.660	0.340	0.000
K81.8 Other cholecystitis	0.658	0.342	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.658	0.342	0.000
C17.2 Ileum	0.658	0.342	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.658	0.342	0.000
C58 Malignant neoplasm of placenta	0.658	0.342	0.000
C52 Malignant neoplasm of vagina	0.658	0.342	0.000
S71 Open wound of hip and thigh	0.658	0.342	0.000
S10-S19 Injuries to the neck	0.657	0.343	0.000
L40.8 Other psoriasis	0.656	0.344	0.000
L40.4 Guttate psoriasis	0.656	0.344	0.000
L40.3 Pustulosis palmaris et plantaris	0.656	0.344	0.000
L40.2 Acrodermatitis continua	0.656	0.344	0.000
L40.1 Generalised pustular psoriasis	0.656	0.344	0.000
F25 Schizoaffective disorders	0.656	0.344	0.000
C67.1 Dome of bladder	0.655	0.344	0.000
C16 Malignant neoplasm of stomach	0.655	0.345	0.000
L44 Other papulosquamous disorders	0.655	0.345	0.000
L41 Parapsoriasis	0.655	0.345	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.655	0.345	0.000
L42 Pityriasis rosea	0.655	0.345	0.000
Q28 Other congenital malformations of circulatory system	0.654	0.346	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.653	0.347	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.653	0.347	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.652	0.348	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.651	0.349	0.000
T79-T79 Certain early complications of trauma	0.651	0.349	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.650	0.350	0.000
F43.8 Other reactions to severe stress	0.650	0.350	0.000
K65-K67 Diseases of peritoneum	0.650	0.350	0.000
T95 Sequelae of burns, corrosions and frostbite	0.649	0.351	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.649	0.351	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.649	0.351	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.649	0.351	0.000
D00-D09 In situ neoplasms	0.649	0.351	0.000
I24.1 Dressler's syndrome	0.000	0.352	0.648
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.647	0.353	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.645	0.355	0.000
F30-F39 Mood [affective] disorders	0.644	0.356	0.000
T93.2 Sequelae of other fractures of lower limb	0.644	0.356	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.644	0.356	0.000
T66-T78 Other and unspecified effects of external causes	0.643	0.357	0.000
K83.5 Biliary cyst	0.641	0.359	0.000
K83.4 Spasm of sphincter of Oddi	0.641	0.359	0.000
K83.3 Fistula of bile duct	0.641	0.359	0.000
K83.2 Perforation of bile duct	0.641	0.359	0.000
K86.2 Cyst of pancreas	0.641	0.359	0.000
S20 Superficial injury of thorax	0.640	0.360	0.000
K86.9 Disease of pancreas, unspecified	0.640	0.360	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.640	0.360	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.360	0.639
C18.8 Overlapping lesion of colon	0.639	0.361	0.000
C18.1 Appendix	0.639	0.361	0.000
X60-X84 Intentional self-harm	0.639	0.361	0.000
T91 Sequelae of injuries of neck and trunk	0.636	0.364	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.635	0.365	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.366	0.634
T90 Sequelae of injuries of head	0.634	0.366	0.000
C67.5 Bladder neck	0.633	0.366	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.634	0.366	0.000
K08 Other disorders of teeth and supporting structures	0.632	0.368	0.000
G20-G26 Extrapyramidal and movement disorders	0.632	0.368	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.631	0.369	0.000
K14.0 Glossitis	0.631	0.369	0.000
C01 Malignant neoplasm of base of tongue	0.630	0.369	0.000
C18.3 Hepatic flexure	0.630	0.369	0.000
Q18 Other congenital malformations of face and neck	0.628	0.372	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.372	0.628
K05 Gingivitis and periodontal diseases	0.628	0.372	0.000
L40.0 Psoriasis vulgaris	0.627	0.373	0.000
F68 Other disorders of adult personality and behaviour	0.626	0.374	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.626	0.374	0.000
F65 Disorders of sexual preference	0.626	0.374	0.000
F64 Gender identity disorders	0.626	0.374	0.000
F63 Habit and impulse disorders	0.626	0.374	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.626	0.374	0.000
F69 Unspecified disorder of adult personality and behaviour	0.626	0.374	0.000
F61 Mixed and other personality disorders	0.626	0.374	0.000
C51 Malignant neoplasm of vulva	0.625	0.374	0.000
G70-G73 Diseases of myoneural junction and muscle	0.625	0.375	0.000
Q63 Other congenital malformations of kidney	0.624	0.376	0.000
X20-X29 Contact with venomous animals and plants	0.623	0.377	0.000
Chapter XXII Codes for special purposes	0.621	0.379	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.620	0.380	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.620	0.380	0.000
T42.3 Barbiturates	0.620	0.380	0.000
T42.2 Succinimides and oxazolidinediones	0.620	0.380	0.000
T42.0 Hydantoin derivatives	0.620	0.380	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.619	0.380	0.000
K85.9 Acute pancreatitis, unspecified	0.619	0.381	0.000
G44 Other headache syndromes	0.619	0.381	0.000
S65 Injury of blood vessels at wrist and hand level	0.618	0.382	0.000
Q39 Congenital malformations of oesophagus	0.618	0.382	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.617	0.383	0.000
K90-K93 Other diseases of the digestive system	0.617	0.383	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.617	0.383	0.000
G83 Other paralytic syndromes	0.615	0.385	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.615	0.385	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.615	0.385	0.000
C31 Malignant neoplasm of accessory sinuses	0.615	0.385	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.615	0.385	0.000
C37 Malignant neoplasm of thymus	0.615	0.385	0.000
C33 Malignant neoplasm of trachea	0.615	0.385	0.000
Q43.8 Other specified congenital malformations of intestine	0.614	0.386	0.000
T31 Burns classified according to extent of body surface involved	0.614	0.386	0.000
F45 Somatoform disorders	0.613	0.387	0.000
C50-C50 Malignant neoplasm of breast	0.613	0.387	0.000
F20.9 Schizophrenia, unspecified	0.613	0.387	0.000
V10-V19 Pedal cyclist injured in transport accident	0.612	0.388	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.612	0.388	0.000
C09 Malignant neoplasm of tonsil	0.612	0.388	0.000
F43.0 Acute stress reaction	0.612	0.388	0.000
F22 Persistent delusional disorders	0.611	0.389	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.608	0.391	0.000
F23 Acute and transient psychotic disorders	0.608	0.392	0.000
Y35-Y36 Legal intervention and operations of war	0.607	0.393	0.000
Y10-Y34 Event of undetermined intent	0.607	0.393	0.000
Y00-Y09 Assault	0.607	0.393	0.000
X85-X99 Assault	0.607	0.393	0.000
X30-X39 Exposure to forces of nature	0.607	0.393	0.000
X00-X09 Exposure to smoke, fire and flames	0.607	0.393	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.607	0.393	0.000
W75-W84 Other accidental threats to breathing	0.607	0.393	0.000
W65-W74 Accidental drowning and submersion	0.607	0.393	0.000
V98-V99 Other and unspecified transport accidents	0.607	0.393	0.000
V95-V97 Air and space transport accidents	0.607	0.393	0.000
V90-V94 Water transport accidents	0.607	0.393	0.000
V70-V79 Bus occupant injured in transport accident	0.607	0.393	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.607	0.393	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.607	0.393	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.607	0.393	0.000
V01-V09 Pedestrian injured in transport accident	0.607	0.393	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.607	0.393	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.606	0.394	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.606	0.394	0.000
T39.4 Antirheumatics, not elsewhere classified	0.606	0.394	0.000
T39.2 Pyrazolone derivatives	0.606	0.394	0.000
F48.0 Neurasthenia	0.606	0.394	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.606	0.394	0.000
L11 Other acantholytic disorders	0.605	0.395	0.000
V20-V29 Motorcycle rider injured in transport accident	0.605	0.395	0.000
K00 Disorders of tooth development and eruption	0.604	0.396	0.000
K11 Diseases of salivary glands	0.603	0.397	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.602	0.398	0.000
Q27 Other congenital malformations of peripheral vascular system	0.602	0.398	0.000
S70.1 Contusion of thigh	0.602	0.398	0.000
T18 Foreign body in alimentary tract	0.602	0.398	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.601	0.399	0.000
O23.5 Infections of the genital tract in pregnancy	0.601	0.399	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.601	0.399	0.000
W29 Contact with other powered hand tools and household machinery	0.600	0.399	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.599	0.401	0.000
C53.8 Overlapping lesion of cervix uteri	0.598	0.402	0.000
C53.1 Exocervix	0.598	0.402	0.000
C53.0 Endocervix	0.598	0.402	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.598	0.402	0.000
C13 Malignant neoplasm of hypopharynx	0.598	0.402	0.000
C11 Malignant neoplasm of nasopharynx	0.598	0.402	0.000
C10 Malignant neoplasm of oropharynx	0.598	0.402	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.598	0.402	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.598	0.402	0.000
C05 Malignant neoplasm of palate	0.598	0.402	0.000
C04 Malignant neoplasm of floor of mouth	0.598	0.402	0.000
C03 Malignant neoplasm of gum	0.598	0.402	0.000
C00 Malignant neoplasm of lip	0.598	0.402	0.000
C12 Malignant neoplasm of pyriform sinus	0.598	0.402	0.000
Chapter VII Diseases of the eye and adnexa	0.598	0.402	0.000
S90-S99 Injuries to the ankle and foot	0.597	0.402	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.597	0.402	0.000
X50-X57 Overexertion, travel and privation	0.597	0.403	0.000
K83.1 Obstruction of bile duct	0.597	0.403	0.000
K45 Other abdominal hernia	0.596	0.404	0.000
L60-L75 Disorders of skin appendages	0.596	0.404	0.000
C17.9 Small intestine, unspecified	0.595	0.405	0.000
Q24 Other congenital malformations of heart	0.595	0.405	0.000
W50-W64 Exposure to animate mechanical forces	0.595	0.405	0.000
C88 Malignant immunoproliferative diseases	0.595	0.405	0.000
O85-O92 Complications predominantly related to the puerperium	0.594	0.406	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.594	0.406	0.000
C34.1 Upper lobe, bronchus or lung	0.592	0.408	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.592	0.408	0.000
Q21.1 Atrial septal defect	0.591	0.409	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.591	0.409	0.000
T45.0 Antiallergic and antiemetic drugs	0.590	0.409	0.000
F28 Other nonorganic psychotic disorders	0.590	0.410	0.000
F24 Induced delusional disorder	0.590	0.410	0.000
F21 Schizotypal disorder	0.590	0.410	0.000
F40 Phobic anxiety disorders	0.589	0.411	0.000
O66 Other obstructed labour	0.589	0.411	0.000
T23 Burn and corrosion of wrist and hand	0.588	0.412	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.588	0.412	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.588	0.412	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.588	0.412	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.588	0.412	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.588	0.412	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.588	0.412	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.587	0.412	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.587	0.413	0.000
S78 Traumatic amputation of hip and thigh	0.586	0.414	0.000
S77 Crushing injury of hip and thigh	0.586	0.414	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.586	0.414	0.000
S75 Injury of blood vessels at hip and thigh level	0.586	0.414	0.000
S74 Injury of nerves at hip and thigh level	0.586	0.414	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.586	0.414	0.000
C17.8 Overlapping lesion of small intestine	0.586	0.414	0.000
C17.3 Meckel's diverticulum	0.586	0.414	0.000
C17.1 Jejunum	0.586	0.414	0.000
Q45 Other congenital malformations of digestive system	0.586	0.414	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.586	0.414	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.586	0.414	0.000
Q40 Other congenital malformations of upper alimentary tract	0.586	0.414	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.586	0.414	0.000
S79 Other and unspecified injuries of hip and thigh	0.585	0.414	0.000
K03 Other diseases of hard tissues of teeth	0.585	0.415	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.585	0.415	0.000
Q26 Congenital malformations of great veins	0.584	0.415	0.000
Q25 Congenital malformations of great arteries	0.584	0.415	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.584	0.415	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.584	0.415	0.000
S00.5 Superficial injury of lip and oral cavity	0.584	0.416	0.000
C54.9 Corpus uteri, unspecified	0.583	0.416	0.000
C54.8 Overlapping lesion of corpus uteri	0.583	0.416	0.000
C54.3 Fundus uteri	0.583	0.416	0.000
C54.2 Myometrium	0.583	0.416	0.000
C54.0 Isthmus uteri	0.583	0.416	0.000
C92 Myeloid leukaemia	0.583	0.417	0.000
O62 Abnormalities of forces of labour	0.583	0.417	0.000
Q05.9 Spina bifida, unspecified	0.582	0.418	0.000
V80-V89 Other land transport accidents	0.581	0.418	0.000
T20 Burn and corrosion of head and neck	0.581	0.419	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.581	0.419	0.000
C82.0 Small cleaved cell, follicular	0.580	0.420	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.578	0.422	0.000
K86.3 Pseudocyst of pancreas	0.577	0.423	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.576	0.424	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.576	0.424	0.000
T43.9 Psychotropic drug, unspecified	0.575	0.425	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.575	0.425	0.000
T43.6 Psychostimulants with abuse potential	0.575	0.425	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.575	0.425	0.000
F60.8 Other specific personality disorders	0.575	0.425	0.000
F60.6 Anxious [avoidant] personality disorder	0.575	0.425	0.000
F60.5 Anankastic personality disorder	0.575	0.425	0.000
F60.4 Histrionic personality disorder	0.575	0.425	0.000
F60.2 Dissocial personality disorder	0.575	0.425	0.000
F60.1 Schizoid personality disorder	0.575	0.425	0.000
F60.0 Paranoid personality disorder	0.575	0.425	0.000
K70-K77 Diseases of liver	0.575	0.425	0.000
T39.0 Salicylates	0.575	0.425	0.000
G03 Meningitis due to other and unspecified causes	0.575	0.425	0.000
C81 Hodgkin's disease	0.574	0.426	0.000
O42 Premature rupture of membranes	0.574	0.426	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.573	0.427	0.000
C95 Leukaemia of unspecified cell type	0.573	0.427	0.000
C94 Other leukaemias of specified cell type	0.573	0.427	0.000
C93 Monocytic leukaemia	0.573	0.427	0.000
C86 Other specified types of T/NK-cell lymphoma	0.573	0.427	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.573	0.427	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.572	0.428	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.572	0.428	0.000
Q07 Other congenital malformations of nervous system	0.572	0.428	0.000
S08 Traumatic amputation of part of head	0.572	0.428	0.000
S07 Crushing injury of head	0.572	0.428	0.000
S04 Injury of cranial nerves	0.572	0.428	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.572	0.428	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.571	0.429	0.000
K14.9 Disease of tongue, unspecified	0.567	0.433	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.567	0.433	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.567	0.433	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.566	0.434	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.566	0.434	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.566	0.434	0.000
T93.1 Sequelae of fracture of femur	0.566	0.434	0.000
T93.0 Sequelae of open wound of lower limb	0.566	0.434	0.000
Q06 Other congenital malformations of spinal cord	0.565	0.434	0.000
Q04 Other congenital malformations of brain	0.565	0.434	0.000
Q03 Congenital hydrocephalus	0.565	0.434	0.000
Q01 Encephalocele	0.565	0.434	0.000
Q00 Anencephaly and similar malformations	0.565	0.434	0.000
Q02 Microcephaly	0.565	0.434	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.565	0.435	0.000
K85.8 Other acute pancreatitis	0.565	0.435	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations