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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118183808
log Bayes Factor = 15.0414
Chromosome 16   position 71,438,393  (GRCh37) Explore rs118183808 on Ensembl!
Variant rs118183808 is part of Cluster X0152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.015 0.000
E70-E90 Metabolic disorders
0.979 0.021 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.978 0.022 0.000
M15-M19 Arthrosis
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.974 0.026 0.000
E78.5 Hyperlipidaemia, unspecified
0.973 0.027 0.000
N20-N23 Urolithiasis
0.969 0.031 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.966 0.034 0.000
S80-S89 Injuries to the knee and lower leg
0.964 0.036 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.961 0.039 0.000
Chapter VIII Diseases of the ear and mastoid process
0.959 0.041 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.958 0.042 0.000
D10-D36 Benign neoplasms
0.958 0.042 0.000
I95 Hypotension
0.957 0.043 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.955 0.045 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.952 0.048 0.000
Chapter I Certain infectious and parasitic diseases
0.952 0.048 0.000
C79 Secondary malignant neoplasm of other sites
0.945 0.055 0.000
I95.9 Hypotension, unspecified
0.942 0.058 0.000
N73 Other female pelvic inflammatory diseases
0.941 0.059 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.938 0.062 0.000
C60-C63 Malignant neoplasms of male genital organs
0.935 0.065 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.931 0.069 0.000
I84 Haemorrhoids
0.929 0.071 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.927 0.073 0.000
C15-C26 Malignant neoplasms of digestive organs
0.926 0.074 0.000
Chapter V Mental and behavioural disorders
0.925 0.075 0.000
N73.6 Female pelvic peritoneal adhesions
0.925 0.075 0.000
N23 Unspecified renal colic
0.920 0.080 0.000
E78.0 Pure hypercholesterolaemia
0.920 0.080 0.000
B95-B98 Bacterial, viral and other infectious agents
0.915 0.085 0.000
C18 Malignant neoplasm of colon
0.908 0.092 0.000
D12.3 Transverse colon
0.905 0.095 0.000
M80-M85 Disorders of bone density and structure
0.904 0.096 0.000
I84.1 Internal haemorrhoids with other complications
0.904 0.096 0.000
M70-M79 Other soft tissue disorders
0.894 0.106 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.892 0.108 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.889 0.111 0.000
C61 Malignant neoplasm of prostate
0.888 0.112 0.000
M16 Coxarthrosis [arthrosis of hip]
0.886 0.114 0.000
M17 Gonarthrosis [arthrosis of knee]
0.885 0.115 0.000
N20 Calculus of kidney and ureter
0.883 0.117 0.000
Z45 Adjustment and management of implanted device
0.882 0.118 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.880 0.120 0.000
S60-S69 Injuries to the wrist and hand
0.873 0.127 0.000
Z47 Other orthopaedic follow-up care
0.871 0.129 0.000
I30-I52 Other forms of heart disease
0.870 0.130 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.867 0.133 0.000
C77.2 Intra-abdominal lymph nodes
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.862 0.138 0.000
Y83.6 Removal of other organ (partial) (total)
0.860 0.140 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.860 0.140 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.860 0.140 0.000
T66-T78 Other and unspecified effects of external causes
0.859 0.141 0.000
M45-M49 Spondylopathies
0.859 0.141 0.000
S82 Fracture of lower leg, including ankle
0.859 0.141 0.000
Z43 Attention to artificial openings
0.858 0.142 0.000
C78.7 Secondary malignant neoplasm of liver
0.853 0.147 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.852 0.148 0.000
Z50 Care involving use of rehabilitation procedures
0.850 0.150 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.847 0.153 0.000
C77.9 Lymph node, unspecified
0.847 0.153 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.844 0.156 0.000
M16.1 Other primary coxarthrosis
0.843 0.157 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.840 0.160 0.000
H65-H75 Diseases of middle ear and mastoid
0.839 0.161 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.837 0.163 0.000
G20-G26 Extrapyramidal and movement disorders
0.836 0.164 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.834 0.166 0.000
G90-G99 Other disorders of the nervous system
0.830 0.170 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.829 0.171 0.000
D12.2 Ascending colon
0.828 0.172 0.000
E10-E14 Diabetes mellitus
0.826 0.174 0.000
N99-N99 Other disorders of the genitourinary system
0.824 0.176 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.822 0.178 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.821 0.179 0.000
S20-S29 Injuries to the thorax
0.817 0.183 0.000
H60-H62 Diseases of external ear
0.815 0.185 0.000
D12.6 Colon, unspecified
0.815 0.185 0.000
M19 Other arthrosis
0.815 0.185 0.000
D12.5 Sigmoid colon
0.815 0.185 0.000
C18.2 Ascending colon
0.814 0.186 0.000
T81 Complications of procedures, not elsewhere classified
0.808 0.192 0.000
S00-S09 Injuries to the head
0.808 0.192 0.000
N10-N16 Renal tubulo-interstitial diseases
0.806 0.194 0.000
N20.1 Calculus of ureter
0.805 0.195 0.000
S83.2 Tear of meniscus, current
0.805 0.195 0.000
M17.1 Other primary gonarthrosis
0.804 0.196 0.000
C79.6 Secondary malignant neoplasm of ovary
0.804 0.196 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.802 0.198 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.801 0.199 0.000
S70-S79 Injuries to the hip and thigh
0.800 0.200 0.000
H90-H95 Other disorders of ear
0.799 0.201 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.798 0.202 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.798 0.202 0.000
G70-G73 Diseases of myoneural junction and muscle
0.797 0.203 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.794 0.206 0.000
C80 Malignant neoplasm without specification of site
0.793 0.207 0.000
D12.0 Caecum
0.792 0.208 0.000
M81 Osteoporosis without pathological fracture
0.790 0.210 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.790 0.210 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.789 0.211 0.000
N30-N39 Other diseases of urinary system
0.788 0.212 0.000
X50-X57 Overexertion, travel and privation
0.788 0.212 0.000
I83 Varicose veins of lower extremities
0.788 0.212 0.000
E10 Insulin-dependent diabetes mellitus
0.788 0.212 0.000
N71 Inflammatory disease of uterus, except cervix
0.783 0.216 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.783 0.217 0.000
N21 Calculus of lower urinary tract
0.780 0.220 0.000
N76 Other inflammation of vagina and vulva
0.779 0.220 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
D22 Melanocytic naevi
0.777 0.223 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.777 0.223 0.000
D23 Other benign neoplasms of skin
0.775 0.225 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.775 0.225 0.000
D12.7 Rectosigmoid junction
0.771 0.229 0.000
W00-W19 Falls
0.769 0.231 0.000
Z43.2 Attention to ileostomy
0.769 0.231 0.000
G56 Mononeuropathies of upper limb
0.766 0.234 0.000
C18.1 Appendix
0.765 0.235 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.764 0.236 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.764 0.236 0.000
Z45.2 Adjustment and management of vascular access device
0.763 0.237 0.000
I84.2 Internal haemorrhoids without complication
0.762 0.238 0.000
B35-B49 Mycoses
0.760 0.240 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.759 0.241 0.000
T78 Adverse effects, not elsewhere classified
0.758 0.241 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.757 0.243 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
I84.9 Unspecified haemorrhoids without complication
0.750 0.250 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.748 0.252 0.000
G25 Other extrapyramidal and movement disorders
0.748 0.252 0.000
C18.3 Hepatic flexure
0.747 0.253 0.000
G50 Disorders of trigeminal nerve
0.746 0.254 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.745 0.255 0.000
H80-H83 Diseases of inner ear
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.744 0.256 0.000
N39 Other disorders of urinary system
0.743 0.257 0.000
E10.9 Without complications
0.741 0.259 0.000
E20-E35 Disorders of other endocrine glands
0.741 0.259 0.000
Z45.8 Adjustment and management of other implanted devices
0.740 0.260 0.000
I95.1 Orthostatic hypotension
0.740 0.260 0.000
T93 Sequelae of injuries of lower limb
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.737 0.263 0.000
M47 Spondylosis
0.737 0.263 0.000
I49 Other cardiac arrhythmias
0.736 0.264 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.735 0.265 0.000
M18 Arthrosis of first carpometacarpal joint
0.735 0.265 0.000
A30-A49 Other bacterial diseases
0.735 0.265 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.735 0.265 0.000
C18.9 Colon, unspecified
0.734 0.266 0.000
Z53.9 Procedure not carried out, unspecified reason
0.734 0.266 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.733 0.267 0.000
I82 Other venous embolism and thrombosis
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.730 0.270 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.271 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.728 0.272 0.000
S80 Superficial injury of lower leg
0.727 0.273 0.000
C77.1 Intrathoracic lymph nodes
0.726 0.274 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.725 0.275 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.725 0.275 0.000
F40 Phobic anxiety disorders
0.724 0.276 0.000
H71 Cholesteatoma of middle ear
0.723 0.277 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.722 0.278 0.000
I47 Paroxysmal tachycardia
0.722 0.278 0.000
I08 Multiple valve diseases
0.722 0.278 0.000
I60-I69 Cerebrovascular diseases
0.721 0.279 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.721 0.279 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.720 0.280 0.000
I34 Nonrheumatic mitral valve disorders
0.720 0.280 0.000
C25 Malignant neoplasm of pancreas
0.720 0.280 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.719 0.281 0.000
S82.4 Fracture of fibula alone
0.719 0.281 0.000
Z36 Antenatal screening
0.718 0.282 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.718 0.282 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Y83.3 Surgical operation with formation of external stoma
0.717 0.283 0.000
M79.8 Other specified soft tissue disorders
0.717 0.283 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
M79.6 Pain in limb
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
I84.5 External haemorrhoids without complication
0.714 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
M05-M14 Inflammatory polyarthropathies
0.714 0.286 0.000
Z34 Supervision of normal pregnancy
0.713 0.287 0.000
C91 Lymphoid leukaemia
0.712 0.288 0.000
O60-O75 Complications of labour and delivery
0.711 0.289 0.000
S89 Other and unspecified injuries of lower leg
0.711 0.289 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.710 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.710 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.709 0.291 0.000
M81.9 Osteoporosis, unspecified
0.709 0.291 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.708 0.292 0.000
H60 Otitis externa
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.708 0.292 0.000
C18.0 Caecum
0.707 0.293 0.000
E40-E46 Malnutrition
0.706 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
M72 Fibroblastic disorders
0.706 0.294 0.000
I46 Cardiac arrest
0.706 0.294 0.000
M79.2 Neuralgia and neuritis, unspecified
0.705 0.295 0.000
N20.9 Urinary calculus, unspecified
0.705 0.295 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.705 0.295 0.000
C77.5 Intrapelvic lymph nodes
0.703 0.297 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.703 0.297 0.000
N39.3 Stress incontinence
0.703 0.297 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.703 0.297 0.000
E88 Other metabolic disorders
0.702 0.298 0.000
E85 Amyloidosis
0.702 0.298 0.000
E84 Cystic fibrosis
0.702 0.298 0.000
E79 Disorders of purine and pyrimidine metabolism
0.702 0.298 0.000
E77 Disorders of glycoprotein metabolism
0.702 0.298 0.000
E76 Disorders of glycosaminoglycan metabolism
0.702 0.298 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.702 0.298 0.000
E74 Other disorders of carbohydrate metabolism
0.702 0.298 0.000
E73 Lactose intolerance
0.702 0.298 0.000
E72 Other disorders of amino-acid metabolism
0.702 0.298 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.702 0.298 0.000
E70 Disorders of aromatic amino-acid metabolism
0.702 0.298 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.702 0.298 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.701 0.299 0.000
W20-W49 Exposure to inanimate mechanical forces
0.701 0.299 0.000
E78.8 Other disorders of lipoprotein metabolism
0.701 0.299 0.000
E78.6 Lipoprotein deficiency
0.701 0.299 0.000
E78.4 Other hyperlipidaemia
0.701 0.299 0.000
E78.3 Hyperchylomicronaemia
0.701 0.299 0.000
E78.2 Mixed hyperlipidaemia
0.701 0.299 0.000
E78.1 Pure hyperglyceridaemia
0.701 0.299 0.000
D24 Benign neoplasm of breast
0.701 0.299 0.000
M15 Polyarthrosis
0.700 0.300 0.000
E50-E64 Other nutritional deficiencies
0.700 0.300 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.700 0.300 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.699 0.300 0.000
M80 Osteoporosis with pathological fracture
0.699 0.301 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.301 0.000
D23.7 Skin of lower limb, including hip
0.699 0.301 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.699 0.301 0.000
C18.6 Descending colon
0.699 0.301 0.000
I42 Cardiomyopathy
0.699 0.301 0.000
Z96 Presence of other functional implants
0.698 0.302 0.000
E86 Volume depletion
0.698 0.302 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.698 0.302 0.000
I99 Other and unspecified disorders of circulatory system
0.698 0.302 0.000
I31 Other diseases of pericardium
0.698 0.302 0.000
M79.7 Fibromyalgia
0.698 0.302 0.000
S81 Open wound of lower leg
0.698 0.302 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.698 0.302 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.698 0.302 0.000
Y83.4 Other reconstructive surgery
0.698 0.302 0.000
Z39 Postpartum care and examination
0.696 0.304 0.000
D11 Benign neoplasm of major salivary glands
0.696 0.304 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.696 0.304 0.000
S69 Other and unspecified injuries of wrist and hand
0.695 0.305 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.695 0.305 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.694 0.306 0.000
G56.0 Carpal tunnel syndrome
0.693 0.307 0.000
Z54 Convalescence
0.693 0.307 0.000
Z52 Donors of organs and tissues
0.693 0.307 0.000
Z49 Care involving dialysis
0.693 0.307 0.000
Z44 Fitting and adjustment of external prosthetic device
0.693 0.307 0.000
Z45.1 Adjustment and management of infusion pump
0.693 0.307 0.000
C18.4 Transverse colon
0.692 0.308 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.692 0.308 0.000
S88 Traumatic amputation of lower leg
0.691 0.309 0.000
S87 Crushing injury of lower leg
0.691 0.309 0.000
S86 Injury of muscle and tendon at lower leg level
0.691 0.309 0.000
S85 Injury of blood vessels at lower leg level
0.691 0.309 0.000
S84 Injury of nerves at lower leg level
0.691 0.309 0.000
Z96.6 Presence of orthopaedic joint implants
0.691 0.309 0.000
Z53.0 Procedure not carried out because of contraindication
0.691 0.309 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.691 0.309 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.690 0.310 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.689 0.311 0.000
G54 Nerve root and plexus disorders
0.689 0.311 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.689 0.311 0.000
M19.9 Arthrosis, unspecified
0.688 0.312 0.000
S61 Open wound of wrist and hand
0.687 0.313 0.000
S51 Open wound of forearm
0.687 0.313 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.687 0.313 0.000
I88 Nonspecific lymphadenitis
0.687 0.313 0.000
I87 Other disorders of veins
0.687 0.313 0.000
I86 Varicose veins of other sites
0.687 0.313 0.000
I81 Portal vein thrombosis
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.687 0.313 0.000
D31 Benign neoplasm of eye and adnexa
0.686 0.313 0.000
D30 Benign neoplasm of urinary organs
0.686 0.313 0.000
D29 Benign neoplasm of male genital organs
0.686 0.313 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.686 0.313 0.000
D26 Other benign neoplasms of uterus
0.686 0.313 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.686 0.313 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.686 0.313 0.000
D19 Benign neoplasm of mesothelial tissue
0.686 0.313 0.000
D16 Benign neoplasm of bone and articular cartilage
0.686 0.313 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.686 0.313 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.686 0.313 0.000
D10 Benign neoplasm of mouth and pharynx
0.686 0.313 0.000
I35 Nonrheumatic aortic valve disorders
0.687 0.313 0.000
N13 Obstructive and reflux uropathy
0.686 0.314 0.000
I95.8 Other hypotension
0.686 0.314 0.000
I95.2 Hypotension due to drugs
0.686 0.314 0.000
I95.0 Idiopathic hypotension
0.686 0.314 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
M85 Other disorders of bone density and structure
0.685 0.315 0.000
M50-M54 Other dorsopathies
0.684 0.316 0.000
D34 Benign neoplasm of thyroid gland
0.684 0.316 0.000
N70 Salpingitis and oophoritis
0.684 0.316 0.000
H66 Suppurative and unspecified otitis media
0.683 0.317 0.000
D12.9 Anus and anal canal
0.682 0.318 0.000
D12.1 Appendix
0.682 0.318 0.000
B99-B99 Other infectious diseases
0.682 0.318 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.682 0.318 0.000
B65-B83 Helminthiases
0.682 0.318 0.000
B50-B64 Protozoal diseases
0.682 0.318 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.682 0.318 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.318 0.000
A75-A79 Rickettsioses
0.682 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.682 0.318 0.000
A65-A69 Other spirochaetal diseases
0.682 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.682 0.318 0.000
A15-A19 Tuberculosis
0.682 0.318 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
M84 Disorders of continuity of bone
0.681 0.318 0.000
D36 Benign neoplasm of other and unspecified sites
0.681 0.319 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.681 0.319 0.000
N60-N64 Disorders of breast
0.681 0.319 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.680 0.320 0.000
M17.0 Primary gonarthrosis, bilateral
0.680 0.320 0.000
S82.0 Fracture of patella
0.680 0.320 0.000
C16 Malignant neoplasm of stomach
0.679 0.321 0.000
D37.5 Rectum
0.678 0.322 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.677 0.323 0.000
C79.2 Secondary malignant neoplasm of skin
0.677 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.677 0.323 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.677 0.323 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.677 0.323 0.000
S64 Injury of nerves at wrist and hand level
0.676 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.676 0.324 0.000
Z41 Procedures for purposes other than remedying health state
0.675 0.325 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.675 0.325 0.000
T78.4 Allergy, unspecified
0.675 0.325 0.000
Z50.2 Alcohol rehabilitation
0.675 0.325 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.675 0.325 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.675 0.325 0.000
N73.5 Female pelvic peritonitis, unspecified
0.675 0.325 0.000
N73.4 Female chronic pelvic peritonitis
0.675 0.325 0.000
N73.3 Female acute pelvic peritonitis
0.675 0.325 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.675 0.325 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.675 0.325 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.675 0.325 0.000
Z48 Other surgical follow-up care
0.674 0.326 0.000
D50-D53 Nutritional anaemias
0.673 0.327 0.000
C77.8 Lymph nodes of multiple regions
0.672 0.327 0.000
C77.4 Inguinal and lower limb lymph nodes
0.672 0.327 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.672 0.328 0.000
C51-C58 Malignant neoplasms of female genital organs
0.672 0.328 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.672 0.328 0.000
D37.2 Small intestine
0.671 0.329 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.670 0.330 0.000
C62 Malignant neoplasm of testis
0.670 0.330 0.000
C60 Malignant neoplasm of penis
0.670 0.330 0.000
G70 Myasthenia gravis and other myoneural disorders
0.670 0.330 0.000
S01 Open wound of head
0.668 0.332 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.668 0.332 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.668 0.332 0.000
Y83.9 Surgical procedure, unspecified
0.667 0.333 0.000
Y83.5 Amputation of limb(s)
0.667 0.333 0.000
Y83.0 Surgical operation with transplant of whole organ
0.667 0.333 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.666 0.334 0.000
I84.3 External thrombosed haemorrhoids
0.666 0.334 0.000
I84.0 Internal thrombosed haemorrhoids
0.666 0.334 0.000
M48 Other spondylopathies
0.665 0.335 0.000
T87 Complications peculiar to reattachment and amputation
0.664 0.335 0.000
T86 Failure and rejection of transplanted organs and tissues
0.664 0.335 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.664 0.335 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.664 0.336 0.000
H90 Conductive and sensorineural hearing loss
0.664 0.336 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.664 0.336 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.664 0.336 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.664 0.336 0.000
C21 Malignant neoplasm of anus and anal canal
0.664 0.336 0.000
C17 Malignant neoplasm of small intestine
0.664 0.336 0.000
C23 Malignant neoplasm of gallbladder
0.664 0.336 0.000
Z47.8 Other specified orthopaedic follow-up care
0.664 0.336 0.000
M47.9 Spondylosis, unspecified
0.664 0.336 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.664 0.336 0.000
D37.0 Lip, oral cavity and pharynx
0.664 0.336 0.000
Z40 Prophylactic surgery
0.663 0.336 0.000
F99-F99 Unspecified mental disorder
0.663 0.337 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.663 0.337 0.000
F80-F89 Disorders of psychological development
0.663 0.337 0.000
F70-F79 Mental retardation
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.663 0.337 0.000
H92 Otalgia and effusion of ear
0.663 0.337 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.663 0.337 0.000
Z42 Follow-up care involving plastic surgery
0.662 0.338 0.000
D32 Benign neoplasm of meninges
0.660 0.340 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.660 0.340 0.000
S82.3 Fracture of lower end of tibia
0.659 0.341 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.658 0.342 0.000
F45 Somatoform disorders
0.658 0.342 0.000
G95 Other diseases of spinal cord
0.657 0.342 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.656 0.344 0.000
I84.4 External haemorrhoids with other complications
0.656 0.344 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.656 0.344 0.000
I27 Other pulmonary heart diseases
0.655 0.345 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.654 0.346 0.000
G25.3 Myoclonus
0.654 0.346 0.000
F40.2 Specific (isolated) phobias
0.653 0.347 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.653 0.347 0.000
H65 Nonsuppurative otitis media
0.653 0.347 0.000
Z12 Special screening examination for neoplasms
0.652 0.348 0.000
N00-N08 Glomerular diseases
0.651 0.348 0.000
C18.8 Overlapping lesion of colon
0.651 0.349 0.000
C18.5 Splenic flexure
0.651 0.349 0.000
Z43.1 Attention to gastrostomy
0.651 0.349 0.000
S79 Other and unspecified injuries of hip and thigh
0.650 0.349 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.650 0.350 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.650 0.350 0.000
S32 Fracture of lumbar spine and pelvis
0.648 0.352 0.000
M83 Adult osteomalacia
0.648 0.352 0.000
M82 Osteoporosis in diseases classified elsewhere
0.648 0.352 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.647 0.353 0.000
I26 Pulmonary embolism
0.645 0.355 0.000
X51 Travel and motion
0.645 0.355 0.000
N21.0 Calculus in bladder
0.645 0.355 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.644 0.356 0.000
M77 Other enthesopathies
0.643 0.357 0.000
Z50.1 Other physical therapy
0.643 0.357 0.000
G50.0 Trigeminal neuralgia
0.642 0.358 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.642 0.358 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.641 0.358 0.000
S52 Fracture of forearm
0.641 0.359 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.641 0.359 0.000
M76 Enthesopathies of lower limb, excluding foot
0.641 0.359 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.641 0.359 0.000
M71 Other bursopathies
0.641 0.359 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.641 0.359 0.000
M17.9 Gonarthrosis, unspecified
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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