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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs889398
log Bayes Factor = 13.1651
Chromosome 16   position 69,556,715  (GRCh37) Explore rs889398 on Ensembl!
Variant rs889398 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80 Cholelithiasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.004 0.996
E11.4 With neurological complications
0.000 0.004 0.996
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.004 0.996
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.010 0.990
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.017 0.983
E11.2 With renal complications
0.000 0.018 0.982
K80.4 Calculus of bile duct with cholecystitis
0.000 0.031 0.969
M10.99 Gout, unspecified (Site unspecified)
0.000 0.032 0.968
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.041 0.959
K83 Other diseases of biliary tract
0.000 0.043 0.957
K83.1 Obstruction of bile duct
0.000 0.061 0.939
H26.9 Cataract, unspecified
0.000 0.088 0.912
K83.8 Other specified diseases of biliary tract
0.000 0.094 0.906
M17.1 Other primary gonarthrosis
0.000 0.126 0.874
K83.9 Disease of biliary tract, unspecified
0.000 0.135 0.865
M17.9 Gonarthrosis, unspecified
0.000 0.156 0.844
M17 Gonarthrosis [arthrosis of knee]
0.000 0.156 0.844
E11.6 With other specified complications
0.000 0.183 0.817
K83.4 Spasm of sphincter of Oddi
0.000 0.262 0.738
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E11.0 With coma
0.000 0.293 0.707
K86 Other diseases of pancreas
0.000 0.308 0.692
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.313 0.687
M17.4 Other secondary gonarthrosis, bilateral
0.000 0.315 0.685
K85 Acute pancreatitis
0.000 0.316 0.684
K83.3 Fistula of bile duct
0.000 0.324 0.675
K83.5 Biliary cyst
0.000 0.325 0.675
K86.8 Other specified diseases of pancreas
0.000 0.335 0.665
K83.0 Cholangitis
0.000 0.344 0.656
M17.3 Other posttraumatic gonarthrosis
0.000 0.350 0.650
K86.9 Disease of pancreas, unspecified
0.000 0.356 0.644
E11.3 With ophthalmic complications
0.000 0.359 0.641
E11.8 With unspecified complications
0.000 0.372 0.628
K83.2 Perforation of bile duct
0.000 0.391 0.608
E11.5 With peripheral circulatory complications
0.000 0.405 0.595
M17.2 Posttraumatic gonarthrosis, bilateral
0.000 0.418 0.582
K85.2 Alcohol-induced acute pancreatitis
0.000 0.424 0.576
K80.8 Other cholelithiasis
0.000 0.446 0.554
M17.5 Other secondary gonarthrosis
0.000 0.463 0.537
K81 Cholecystitis
0.000 0.465 0.535
I50 Heart failure
0.000 0.466 0.534
I50.0 Congestive heart failure
0.000 0.471 0.529
E11.1 With ketoacidosis
0.000 0.475 0.525
I42.0 Dilated cardiomyopathy
0.000 0.481 0.519
I30-I52 Other forms of heart disease
0.000 0.484 0.516
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
I42 Cardiomyopathy
0.000 0.490 0.510
I35 Nonrheumatic aortic valve disorders
0.000 0.494 0.506
I50.9 Heart failure, unspecified
0.000 0.495 0.505
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.507 0.493
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.507 0.493
K85.3 Drug-induced acute pancreatitis
0.000 0.510 0.490
K85.0 Idiopathic acute pancreatitis
0.000 0.510 0.490
K85.8 Other acute pancreatitis
0.000 0.511 0.489
K85.9 Acute pancreatitis, unspecified
0.000 0.517 0.483
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.518 0.482
I50.1 Left ventricular failure
0.000 0.527 0.473
I30 Acute pericarditis
0.000 0.529 0.471
I35.8 Other aortic valve disorders
0.000 0.544 0.456
I36 Nonrheumatic tricuspid valve disorders
0.000 0.546 0.454
I30.9 Acute pericarditis, unspecified
0.000 0.557 0.443
K81.0 Acute cholecystitis
0.000 0.565 0.435
I42.9 Cardiomyopathy, unspecified
0.000 0.576 0.424
I44 Atrioventricular and left bundle-branch block
0.000 0.585 0.415
I44.7 Left bundle-branch block, unspecified
0.000 0.588 0.412
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.591 0.409
I51 Complications and ill-defined descriptions of heart disease
0.000 0.593 0.407
I35.1 Aortic (valve) insufficiency
0.000 0.602 0.398
I10 Essential (primary) hypertension
0.000 0.608 0.392
I35.0 Aortic (valve) stenosis
0.000 0.608 0.392
I46 Cardiac arrest
0.000 0.612 0.388
I10-I15 Hypertensive diseases
0.000 0.614 0.386
K81.1 Chronic cholecystitis
0.000 0.614 0.386
I45 Other conduction disorders
0.000 0.616 0.384
I95 Hypotension
0.000 0.617 0.383
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.618 0.382
Chapter IX Diseases of the circulatory system
0.000 0.619 0.381
I95.2 Hypotension due to drugs
0.000 0.620 0.380
I42.6 Alcoholic cardiomyopathy
0.000 0.628 0.372
I95.1 Orthostatic hypotension
0.000 0.628 0.372
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.629 0.371
I52 Other heart disorders in diseases classified elsewhere
0.000 0.630 0.370
I48 Atrial fibrillation and flutter
0.000 0.630 0.370
I41 Myocarditis in diseases classified elsewhere
0.000 0.630 0.370
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.630 0.370
I32 Pericarditis in diseases classified elsewhere
0.000 0.630 0.370
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.635 0.365
I42.4 Endocardial fibroelastosis
0.000 0.635 0.365
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.635 0.365
K81.8 Other cholecystitis
0.000 0.637 0.363
I42.5 Other restrictive cardiomyopathy
0.000 0.645 0.355
I51.6 Cardiovascular disease, unspecified
0.000 0.648 0.352
I44.2 Atrioventricular block, complete
0.000 0.651 0.349
K85.1 Biliary acute pancreatitis
0.000 0.654 0.345
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.658 0.342
I51.0 Cardiac septal defect, acquired
0.000 0.658 0.342
I15 Secondary hypertension
0.000 0.658 0.342
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.661 0.339
I30.8 Other forms of acute pericarditis
0.000 0.662 0.338
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.662 0.338
I42.8 Other cardiomyopathies
0.000 0.667 0.333
I46.0 Cardiac arrest with successful resuscitation
0.000 0.667 0.333
I40 Acute myocarditis
0.000 0.668 0.331
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.670 0.330
I37 Pulmonary valve disorders
0.000 0.671 0.328
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.674 0.326
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.674 0.326
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.674 0.326
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.674 0.326
K86.1 Other chronic pancreatitis
0.000 0.676 0.324
M10.9 Gout, unspecified
0.000 0.683 0.317
I30.1 Infective pericarditis
0.000 0.683 0.317
I97.1 Other functional disturbances following cardiac surgery
0.000 0.686 0.314
I51.4 Myocarditis, unspecified
0.000 0.690 0.310
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.695 0.305
I15.9 Seconday hypertension, unspecified
0.000 0.697 0.303
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.699 0.301
I45.9 Conduction disorder, unspecified
0.000 0.700 0.300
I45.4 Nonspecific intraventricular block
0.000 0.701 0.299
I45.5 Other specified heart block
0.000 0.701 0.299
K82 Other diseases of gallbladder
0.000 0.701 0.299
I44.5 Left posterior fascicular block
0.000 0.702 0.298
I45.2 Bifascicular block
0.000 0.704 0.296
I51.5 Myocardial degeneration
0.000 0.708 0.292
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.708 0.292
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.709 0.290
I11 Hypertensive heart disease
0.000 0.709 0.290
E10-E14 Diabetes mellitus
0.000 0.711 0.289
I33 Acute and subacute endocarditis
0.000 0.716 0.284
I95.0 Idiopathic hypotension
0.000 0.721 0.279
I46.1 Sudden cardiac death, so described
0.000 0.721 0.278
I35.9 Aortic valve disorder, unspecified
0.000 0.722 0.278
I44.4 Left anterior fascicular block
0.000 0.722 0.277
I13 Hypertensive heart and renal disease
0.000 0.723 0.277
I45.1 Other and unspecified right bundle-branch block
0.000 0.724 0.276
I15.1 Hypertension secondary to other renal disorders
0.000 0.731 0.269
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.732 0.267
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.733 0.266
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.733 0.266
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.733 0.266
I45.8 Other specified conduction disorders
0.000 0.734 0.266
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.734 0.266
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.734 0.266
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.734 0.266
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.734 0.266
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.734 0.266
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.734 0.266
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.734 0.266
I48.4 Atypical atrial flutter
0.000 0.734 0.266
I48.3 Typical atrial flutter
0.000 0.734 0.266
I48.2 Chronic atrial fibrillation
0.000 0.734 0.266
I48.1 Persistent atrial fibrillation
0.000 0.734 0.266
I48.0 Paroxysmal atrial fibrillation
0.000 0.734 0.266
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.734 0.266
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.734 0.266
K82.0 Obstruction of gallbladder
0.000 0.739 0.261
I44.3 Other and unspecified atrioventricular block
0.000 0.739 0.261
M10.93 Gout, unspecified (Forearm)
0.000 0.745 0.255
I00-I02 Acute rheumatic fever
0.000 0.746 0.254
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.747 0.252
I45.6 Preexcitation syndrome
0.000 0.748 0.252
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.754 0.246
I15.8 Other secondary hypertension
0.000 0.755 0.245
I15.2 Hypertension secondary to endocrine disorders
0.000 0.755 0.245
I45.3 Trifascicular block
0.000 0.757 0.243
I95.8 Other hypotension
0.000 0.758 0.242
I45.0 Right fascicular block
0.000 0.758 0.242
I97.0 Postcardiotomy syndrome
0.000 0.761 0.239
I40.9 Acute myocarditis, unspecified
0.000 0.762 0.238
I40.8 Other acute myocarditis
0.000 0.762 0.238
I40.1 Isolated myocarditis
0.000 0.762 0.238
I15.0 Renovascular hypertension
0.000 0.764 0.236
I37.9 Pulmonary valve disorder, unspecified
0.000 0.764 0.236
I37.8 Other pulmonary valve disorders
0.000 0.764 0.236
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.764 0.236
M10.94 Gout, unspecified (Hand)
0.000 0.765 0.235
I51.8 Other ill-defined heart diseases
0.000 0.769 0.231
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.772 0.228
E14 Unspecified diabetes mellitus
0.000 0.772 0.228
M10.98 Gout, unspecified (Other)
0.000 0.773 0.227
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.773 0.227
M10.91 Gout, unspecified (Shoulder region)
0.000 0.773 0.227
K82.1 Hydrops of gallbladder
0.000 0.778 0.222
I33.9 Acute endocarditis, unspecified
0.000 0.778 0.222
I37.1 Pulmonary valve insufficiency
0.000 0.778 0.222
E14.9 Without complications
0.000 0.778 0.222
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.779 0.221
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.784 0.216
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.784 0.216
I98.0 Cardiovascular syphilis
0.000 0.784 0.216
I51.7 Cardiomegaly
0.000 0.784 0.216
I44.6 Other and unspecified fascicular block
0.000 0.786 0.214
I37.0 Pulmonary valve stenosis
0.000 0.789 0.211
M10.90 Gout, unspecified (Multiple sites)
0.000 0.789 0.211
K82.3 Fistula of gallbladder
0.000 0.790 0.210
E12 Malnutrition-related diabetes mellitus
0.000 0.793 0.207
I46.9 Cardiac arrest, unspecified
0.000 0.795 0.205
M10.92 Gout, unspecified (Upper arm)
0.000 0.796 0.204
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.800 0.200
I40.0 Infective myocarditis
0.000 0.801 0.199
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.801 0.199
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.801 0.199
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.801 0.199
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.801 0.199
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.802 0.198
I02 Rheumatic chorea
0.000 0.817 0.182
I01 Rheumatic fever with heart involvement
0.000 0.817 0.182
I51.9 Heart disease, unspecified
0.000 0.818 0.182
E13 Other specified diabetes mellitus
0.000 0.818 0.182
E14.2 Withrenal complications
0.000 0.826 0.173
K82.8 Other specified diseases of gallbladder
0.000 0.829 0.171
E14.4 With neurological complications
0.000 0.834 0.166
K86.3 Pseudocyst of pancreas
0.001 0.835 0.165
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.836 0.164
I00 Rheumatic fever without mention of heart involvement
0.000 0.836 0.164
K82.2 Perforation of gallbladder
0.000 0.836 0.164
E14.7 With multiple complications
0.000 0.836 0.163
E14.0 With coma
0.000 0.836 0.163
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.838 0.162
I12 Hypertensive renal disease
0.000 0.839 0.161
I34 Nonrheumatic mitral valve disorders
0.000 0.840 0.160
I31 Other diseases of pericardium
0.000 0.841 0.159
I05-I09 Chronic rheumatic heart diseases
0.000 0.841 0.159
E14.5 With peripheral circulatory complications
0.000 0.848 0.151
E12.9 Without complications
0.000 0.851 0.149
E12.8 With unspecified complications
0.000 0.851 0.149
E12.7 With multiple complications
0.000 0.851 0.149
E12.6 With other specified complications
0.000 0.851 0.149
E12.5 With peripheral circulatory complications
0.000 0.851 0.149
E12.4 With neurological complications
0.000 0.851 0.149
E12.3 With ophthalmic complications
0.000 0.851 0.149
E12.2 With renal complications
0.000 0.851 0.149
E12.1 With ketoacidosis
0.000 0.851 0.149
E12.0 With coma
0.000 0.851 0.149
E14.1 With ketoacidosis
0.000 0.854 0.146
E14.6 With other specified complications
0.000 0.858 0.142
I99 Other and unspecified disorders of circulatory system
0.000 0.861 0.139
E14.8 With unspecified complications
0.000 0.862 0.138
I05 Rheumatic mitral valve diseases
0.000 0.862 0.138
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.869 0.131
I01.8 Other acute rheumatic heart disease
0.000 0.869 0.131
I01.2 Acute rheumatic myocarditis
0.000 0.869 0.131
I01.1 Acute rheumatic endocarditis
0.000 0.869 0.131
I01.0 Acute rheumatic pericarditis
0.000 0.869 0.131
I02.9 Rheumatic chorea without heart involvement
0.000 0.869 0.131
I02.0 Rheumatic chorea with heart involvement
0.000 0.869 0.131
E13.8 With unspecified complications
0.000 0.869 0.131
E13.7 With multiple complications
0.000 0.869 0.131
E13.6 With other specified complications
0.000 0.869 0.131
E13.5 With peripheral circulatory complications
0.000 0.869 0.131
E13.4 With neurological complications
0.000 0.869 0.131
E13.2 With renal complications
0.000 0.869 0.131
E13.1 With ketoacidosis
0.000 0.869 0.131
E13.0 With coma
0.000 0.869 0.131
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.876 0.124
E13.9 Without complications
0.000 0.878 0.121
K81.9 Cholecystitis, unspecified
0.000 0.880 0.120
I05.1 Rheumatic mitral insufficiency
0.000 0.881 0.119
M10.96 Gout, unspecified (Lower leg)
0.000 0.881 0.119
I31.0 Chronic adhesive pericarditis
0.000 0.882 0.118
E13.3 With ophthalmic complications
0.000 0.883 0.117
K82.9 Disease of gallbladder, unspecified
0.000 0.883 0.117
I31.1 Chronic constrictive pericarditis
0.000 0.884 0.116
I28 Other diseases of pulmonary vessels
0.000 0.884 0.116
I05.9 Mitral valve disease, unspecified
0.000 0.884 0.116
I42.2 Other hypertrophic cardiomyopathy
0.001 0.885 0.114
I31.8 Other specified diseases of pericardium
0.000 0.885 0.114
I31.2 Haemopericardium, not elsewhere classified
0.000 0.885 0.114
K86.2 Cyst of pancreas
0.001 0.888 0.111
I34.0 Mitral (valve) insufficiency
0.000 0.889 0.111
I44.1 Atrioventricular block, second degree
0.000 0.891 0.109
M10 Gout
0.000 0.892 0.108
I05.2 Mitral stenosis with insufficiency
0.000 0.894 0.106
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.894 0.105
I47 Paroxysmal tachycardia
0.000 0.899 0.101
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.901 0.099
I05.8 Other mitral valve diseases
0.000 0.901 0.099
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.903 0.097
I09 Other rheumatic heart diseases
0.000 0.904 0.096
E65-E68 Obesity and other hyperalimentation
0.000 0.905 0.095
I49 Other cardiac arrhythmias
0.000 0.910 0.090
I06 Rheumatic aortic valve diseases
0.000 0.911 0.089
E40-E46 Malnutrition
0.000 0.911 0.089
K82.4 Cholesterolosis of gallbladder
0.000 0.912 0.088
E66 Obesity
0.000 0.912 0.088
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.913 0.087
M17.0 Primary gonarthrosis, bilateral
0.000 0.913 0.087
I12.0 Hypertensive renal disease with renal failure
0.000 0.915 0.085
E65 Localised adiposity
0.000 0.915 0.085
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.916 0.084
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.916 0.083
I28.1 Aneurysm of pulmonary artery
0.000 0.916 0.083
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.916 0.083
I28.8 Other specified diseases of pulmonary vessels
0.000 0.917 0.083
I38 Endocarditis, valve unspecified
0.000 0.917 0.083
E46 Unspecified protein-energy malnutrition
0.000 0.917 0.083
I07 Rheumatic tricuspid valve diseases
0.000 0.920 0.080
I49.4 Other and unspecified premature depolarisation
0.000 0.920 0.080
E66.9 Obesity, unspecified
0.000 0.921 0.079
I27 Other pulmonary heart diseases
0.000 0.921 0.079
M10.4 Other secondary gout
0.000 0.922 0.077
M10.3 Gout due to impairment of renal function
0.000 0.922 0.077
M10.2 Drug-induced gout
0.000 0.922 0.077
M10.1 Lead-induced gout
0.000 0.922 0.077
I49.9 Cardiac arrhythmia, unspecified
0.000 0.923 0.077
I26 Pulmonary embolism
0.000 0.923 0.077
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.924 0.076
I05.0 Mitral stenosis
0.000 0.928 0.072
I47.0 Reentry ventricular arrhythmia
0.000 0.930 0.070
I08 Multiple valve diseases
0.000 0.930 0.070
I09.8 Other specified rheumatic heart diseases
0.000 0.931 0.069
I09.2 Chronic rheumatic pericarditis
0.000 0.931 0.069
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.931 0.069
I09.0 Rheumatic myocarditis
0.000 0.931 0.069
I33.0 Acute and subacute infective endocarditis
0.001 0.931 0.069
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.931 0.069
E67 Other hyperalimentation
0.000 0.932 0.068
E68 Sequelae of hyperalimentation
0.000 0.932 0.068
E10 Insulin-dependent diabetes mellitus
0.000 0.933 0.067
M10.0 Idiopathic gout
0.000 0.935 0.065
I12.9 Hypertensive renal disease without renal failure
0.000 0.935 0.065
I49.2 Junctional premature depolarisation
0.000 0.935 0.064
I06.8 Other rheumatic aortic valve diseases
0.000 0.936 0.064
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.936 0.064
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.936 0.064
E45 Retarded development following protein-energy malnutrition
0.000 0.936 0.064
E43 Unspecified severe protein-energy malnutrition
0.000 0.936 0.064
E42 Marasmic kwashiorkor
0.000 0.936 0.064
E41 Nutritional marasmus
0.000 0.936 0.064
E40 Kwashiorkor
0.000 0.936 0.064
E66.1 Drug-induced obesity
0.000 0.936 0.063
E10.9 Without complications
0.000 0.937 0.063
I06.1 Rheumatic aortic insufficiency
0.000 0.937 0.062
E14.3 With ophthalmic complications
0.000 0.938 0.062
E16 Other disorders of pancreatic internal secretion
0.000 0.939 0.061
I31.9 Disease of pericardium, unspecified
0.000 0.939 0.061
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.941 0.058
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.942 0.058
I95.9 Hypotension, unspecified
0.000 0.942 0.058
I27.2 Other secondary pulmonary hypertension
0.000 0.942 0.058
I07.9 Tricuspid valve disease, unspecified
0.000 0.942 0.057
I07.8 Other tricuspid valve diseases
0.000 0.942 0.057
I07.2 Tricuspid stenosis with insufficiency
0.000 0.942 0.057
I07.0 Tricuspid stenosis
0.000 0.942 0.057
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.943 0.056
I27.1 Kyphoscoliotic heart disease
0.000 0.943 0.056
E50-E64 Other nutritional deficiencies
0.000 0.944 0.056
I27.8 Other specified pulmonary heart diseases
0.000 0.944 0.056
M10.19 Lead-induced gout (Site unspecified)
0.000 0.944 0.056
M10.18 Lead-induced gout (Other)
0.000 0.944 0.056
M10.17 Lead-induced gout (Ankle and foot)
0.000 0.944 0.056
M10.16 Lead-induced gout (Lower leg)
0.000 0.944 0.056
M10.15 Lead-induced gout (Pelvic region and thigh)
0.000 0.944 0.056
M10.14 Lead-induced gout (Hand)
0.000 0.944 0.056
M10.13 Lead-induced gout (Forearm)
0.000 0.944 0.056
M10.12 Lead-induced gout (Upper arm)
0.000 0.944 0.056
M10.11 Lead-induced gout (Shoulder region)
0.000 0.944 0.056
M10.10 Lead-induced gout (Multiple sites)
0.000 0.944 0.056
M10.29 Drug-induced gout (Site unspecified)
0.000 0.944 0.056
M10.28 Drug-induced gout (Other)
0.000 0.944 0.056
M10.27 Drug-induced gout (Ankle and foot)
0.000 0.944 0.056
M10.26 Drug-induced gout (Lower leg)
0.000 0.944 0.056
M10.25 Drug-induced gout (Pelvic region and thigh)
0.000 0.944 0.056
M10.24 Drug-induced gout (Hand)
0.000 0.944 0.056
M10.23 Drug-induced gout (Forearm)
0.000 0.944 0.056
M10.22 Drug-induced gout (Upper arm)
0.000 0.944 0.056
M10.21 Drug-induced gout (Shoulder region)
0.000 0.944 0.056
M10.20 Drug-induced gout (Multiple sites)
0.000 0.944 0.056
M10.39 Gout due to impairment of renal function (Site unspecified)
0.000 0.944 0.056
M10.38 Gout due to impairment of renal function (Other)
0.000 0.944 0.056
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.000 0.944 0.056
M10.36 Gout due to impairment of renal function (Lower leg)
0.000 0.944 0.056
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.000 0.944 0.056
M10.34 Gout due to impairment of renal function (Hand)
0.000 0.944 0.056
M10.33 Gout due to impairment of renal function (Forearm)
0.000 0.944 0.056
M10.32 Gout due to impairment of renal function (Upper arm)
0.000 0.944 0.056
M10.31 Gout due to impairment of renal function (Shoulder region)
0.000 0.944 0.056
M10.30 Gout due to impairment of renal function (Multiple sites)
0.000 0.944 0.056
M10.49 Other secondary gout (Site unspecified)
0.000 0.944 0.056
M10.48 Other secondary gout (Other)
0.000 0.944 0.056
M10.47 Other secondary gout (Ankle and foot)
0.000 0.944 0.056
M10.46 Other secondary gout (Lower leg)
0.000 0.944 0.056
M10.45 Other secondary gout (Pelvic region and thigh)
0.000 0.944 0.056
M10.44 Other secondary gout (Hand)
0.000 0.944 0.056
M10.43 Other secondary gout (Forearm)
0.000 0.944 0.056
M10.42 Other secondary gout (Upper arm)
0.000 0.944 0.056
M10.41 Other secondary gout (Shoulder region)
0.000 0.944 0.056
M10.40 Other secondary gout (Multiple sites)
0.000 0.944 0.056
E10.8 With unspecified complications
0.000 0.945 0.055
E15 Nondiabetic hypoglycaemic coma
0.000 0.945 0.055
E66.0 Obesity due to excess calories
0.000 0.945 0.055
I06.0 Rheumatic aortic stenosis
0.000 0.948 0.052
I49.1 Atrial premature depolarisation
0.000 0.948 0.052
I09.9 Rheumatic heart disease, unspecified
0.000 0.948 0.051
I08.9 Multiple valve disease, unspecified
0.000 0.949 0.050
E16.2 Hypoglycaemia, unspecified
0.000 0.950 0.050
E53 Deficiency of other B group vitamins
0.000 0.950 0.050
I08.8 Other multiple valve diseases
0.000 0.950 0.050
E67.8 Other specified hyperalimentation
0.000 0.951 0.049
E67.3 Hypervitaminosis D
0.000 0.951 0.049
E67.2 Megavitamin-B6 syndrome
0.000 0.951 0.049
E67.1 Hypercarotenaemia
0.000 0.951 0.049
E67.0 Hypervitaminosis A
0.000 0.951 0.049
M10.04 Idiopathic gout (Hand)
0.000 0.951 0.048
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.952 0.048
I27.9 Pulmonary heart disease, unspecified
0.000 0.952 0.047
M10.08 Idiopathic gout (Other)
0.000 0.953 0.047
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.953 0.047
M10.03 Idiopathic gout (Forearm)
0.000 0.953 0.047
M10.01 Idiopathic gout (Shoulder region)
0.000 0.953 0.047
M10.00 Idiopathic gout (Multiple sites)
0.000 0.953 0.047
M10.09 Idiopathic gout (Site unspecified)
0.000 0.954 0.046
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.954 0.046
E44.1 Mild protein-energy malnutrition
0.000 0.954 0.046
E44.0 Moderate protein-energy malnutrition
0.000 0.954 0.046
E10.0 With coma
0.000 0.954 0.046
E10.7 With multiple complications
0.000 0.955 0.045
E53.8 Deficiency of other specified B group vitamins
0.000 0.955 0.045
I49.3 Ventricular premature depolarisation
0.000 0.956 0.044
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.956 0.044
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.956 0.044
E16.4 Abnormal secretion of gastrin
0.000 0.956 0.044
E16.3 Increased secretion of glucagon
0.000 0.956 0.044
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.956 0.044
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.956 0.044
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.956 0.044
M10.06 Idiopathic gout (Lower leg)
0.000 0.956 0.043
E10.2 With renal complications
0.000 0.957 0.043
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.959 0.040
E63 Other nutritional deficiencies
0.000 0.959 0.040
E50 Vitamin A deficiency
0.000 0.959 0.040
E60 Dietary zinc deficiency
0.000 0.959 0.040
E59 Dietary selenium deficiency
0.000 0.959 0.040
E54 Ascorbic acid deficiency
0.000 0.959 0.040
E52 Niacin deficiency [pellagra]
0.000 0.959 0.040
E66.8 Other obesity
0.000 0.960 0.040
E16.1 Other hypoglycaemia
0.000 0.960 0.040
E10.4 With neurological complications
0.000 0.960 0.040
I78 Diseases of capillaries
0.000 0.961 0.039
M10.02 Idiopathic gout (Upper arm)
0.000 0.963 0.037
E58 Dietary calcium deficiency
0.000 0.963 0.037
E51 Thiamine deficiency
0.000 0.963 0.037
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.963 0.037
H26 Other cataract
0.000 0.963 0.037
E53.9 Vitamin B deficiency, unspecified
0.000 0.964 0.036
E56 Other vitamin deficiencies
0.000 0.964 0.036
E53.1 Pyridoxine deficiency
0.000 0.964 0.036
E53.0 Riboflavin deficiency
0.000 0.964 0.036
I70 Atherosclerosis
0.000 0.965 0.035
E61 Deficiency of other nutrient elements
0.000 0.965 0.035
I44.0 Atrioventricular block, first degree
0.000 0.966 0.034
I27.0 Primary pulmonary hypertension
0.000 0.967 0.033
I71 Aortic aneurysm and dissection
0.000 0.967 0.033
E10.1 With ketoacidosis
0.000 0.968 0.032
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.969 0.031
E55 Vitamin D deficiency
0.000 0.969 0.031
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.970 0.030
I78.8 Other diseases of capillaries
0.000 0.970 0.030
E50.9 Vitamin A deficiency, unspecified
0.000 0.971 0.029
E50.8 Other manifestations of vitamin A deficiency
0.000 0.971 0.029
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.971 0.029
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.971 0.029
E50.5 Vitamin A deficiency with night blindness
0.000 0.971 0.029
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.971 0.029
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.971 0.029
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.971 0.029
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.971 0.029
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.971 0.029
E63.9 Nutritional deficiency, unspecified
0.000 0.971 0.029
E63.8 Other specified nutritional deficiencies
0.000 0.971 0.029
E63.1 Imbalance of constituents of food intake
0.000 0.971 0.029
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.971 0.029
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.971 0.029
E64.8 Sequelae of other nutritional deficiencies
0.000 0.971 0.029
E64.3 Sequelae of rickets
0.000 0.971 0.029
E64.2 Sequelae of vitamin C deficiency
0.000 0.971 0.029
E64.1 Sequelae of vitamin A deficiency
0.000 0.971 0.029
E64.0 Sequelae of protein-energy malnutrition
0.000 0.971 0.029
I47.2 Ventricular tachycardia
0.000 0.971 0.029
I31.3 Pericardial effusion (noninflammatory)
0.000 0.972 0.028
I78.9 Disease of capillaries, unspecified
0.000 0.972 0.028
H26.0 Infantile, juvenile and presenile cataract
0.000 0.972 0.028
E61.2 Magnesium deficiency
0.000 0.973 0.027
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.973 0.027
E51.9 Thiamine deficiency, unspecified
0.000 0.973 0.026
E51.8 Other manifestations of thiamine deficiency
0.000 0.973 0.026
E51.1 Beriberi
0.000 0.973 0.026
I70.9 Generalised and unspecified atherosclerosis
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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