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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11248850
log Bayes Factor = 0.279278
Chromosome 16   position 163,598  (GRCh37) Explore rs11248850 on Ensembl!
Variant rs11248850 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D68 Other coagulation defects
0.449 0.551 0.000
D69.6 Thrombocytopenia, unspecified
0.448 0.552 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.440 0.560 0.000
D69 Purpura and other haemorrhagic conditions
0.440 0.560 0.000
D68.8 Other specified coagulation defects
0.428 0.572 0.000
D68.0 Von Willebrand's disease
0.426 0.574 0.000
D68.5 Primary Thrombophilia
0.383 0.617 0.000
D68.6 Other Thrombophilia
0.375 0.625 0.000
D68.2 Hereditary deficiency of other clotting factors
0.371 0.629 0.000
D66 Hereditary factor VIII deficiency
0.355 0.645 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.350 0.650 0.000
D69.1 Qualitative platelet defects
0.337 0.663 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.331 0.669 0.000
D68.4 Acquired coagulation factor deficiency
0.330 0.670 0.000
D68.9 Coagulation defect, unspecified
0.327 0.673 0.000
D69.0 Allergic purpura
0.325 0.675 0.000
D67 Hereditary factor IX deficiency
0.325 0.675 0.000
D69.4 Other primary thrombocytopenia
0.318 0.682 0.000
D68.1 Hereditary factor XI deficiency
0.315 0.685 0.000
D69.8 Other specified haemorrhagic conditions
0.315 0.685 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.272 0.728 0.000
D69.2 Other nonthrombocytopenic purpura
0.270 0.730 0.000
D69.9 Haemorrhagic condition, unspecified
0.250 0.750 0.000
D69.5 Secondary thrombocytopenia
0.229 0.771 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.917 0.083
H72 Perforation of tympanic membrane
0.000 0.936 0.064
H72.0 Central perforation of tympanic membrane
0.000 0.940 0.060
G91.9 Hydrocephalus, unspecified
0.054 0.946 0.000
G93 Other disorders of brain
0.053 0.947 0.000
G91 Hydrocephalus
0.053 0.947 0.000
G93.2 Benign intracranial hypertension
0.053 0.947 0.000
G90-G99 Other disorders of the nervous system
0.053 0.947 0.000
G93.4 Encephalopathy, unspecified
0.050 0.950 0.000
G95 Other diseases of spinal cord
0.048 0.952 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.047 0.953 0.000
G96 Other disorders of central nervous system
0.046 0.954 0.000
G93.9 Disorder of brain, unspecified
0.046 0.954 0.000
H72.1 Attic perforation of tympanic membrane
0.000 0.954 0.045
G93.5 Compression of brain
0.045 0.955 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.045 0.955 0.000
G95.2 Cord compression, unspecified
0.045 0.955 0.000
H72.8 Other perforations of tympanic membrane
0.000 0.955 0.045
G95.0 Syringomyelia and syringobulbia
0.045 0.955 0.000
G90 Disorders of autonomic nervous system
0.044 0.956 0.000
H72.2 Other marginal perforations of tympanic membrane
0.000 0.958 0.042
G91.8 Other hydrocephalus
0.040 0.960 0.000
G90.2 Horner's syndrome
0.040 0.960 0.000
G91.2 Normal-pressure hydrocephalus
0.040 0.960 0.000
G96.8 Other specified disorders of central nervous system
0.039 0.961 0.000
G93.7 Reye's syndrome
0.038 0.961 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.038 0.962 0.000
G92 Toxic encephalopathy
0.038 0.962 0.000
G91.0 Communicating hydrocephalus
0.037 0.963 0.000
G93.3 Postviral fatigue syndrome
0.037 0.963 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.037 0.963 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.037 0.963 0.000
G91.1 Obstructive hydrocephalus
0.035 0.965 0.000
G96.0 Cerebrospinal fluid leak
0.035 0.965 0.000
G96.9 Disorder of central nervous system, unspecified
0.033 0.967 0.000
G90.8 Other disorders of autonomic nervous system
0.032 0.967 0.000
G90.4 Autonomic dysreflexia
0.032 0.968 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.032 0.968 0.000
I05.9 Mitral valve disease, unspecified
0.030 0.970 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.029 0.971 0.000
G95.8 Other specified diseases of spinal cord
0.028 0.972 0.000
G90.3 Multisystem degeneration
0.028 0.972 0.000
G95.1 Vascular myelopathies
0.028 0.972 0.000
G93.0 Cerebral cysts
0.028 0.972 0.000
H65-H75 Diseases of middle ear and mastoid
0.000 0.972 0.028
I05 Rheumatic mitral valve diseases
0.027 0.973 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.974 0.026
G99 Other disorders of nervous system in diseases classified elsewhere
0.026 0.974 0.000
H66 Suppurative and unspecified otitis media
0.000 0.974 0.026
I05.0 Mitral stenosis
0.025 0.975 0.000
I05.2 Mitral stenosis with insufficiency
0.024 0.976 0.000
H70 Mastoiditis and related conditions
0.000 0.977 0.023
H69 Other disorders of Eustachian tube
0.000 0.977 0.023
G95.9 Disease of spinal cord, unspecified
0.022 0.978 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.978 0.021
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.021 0.979 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.021 0.979 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.000 0.979 0.021
K11.6 Mucocele of salivary gland
0.021 0.979 0.000
I05.8 Other mitral valve diseases
0.021 0.979 0.000
K11.8 Other diseases of salivary glands
0.021 0.979 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.020 0.979 0.000
H66.4 Suppurative otitis media, unspecified
0.000 0.979 0.020
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.980 0.020
H67 Otitis media in diseases classified elsewhere
0.000 0.980 0.020
K11 Diseases of salivary glands
0.020 0.980 0.000
H68 Eustachian salpingitis and obstruction
0.000 0.980 0.020
I44.7 Left bundle-branch block, unspecified
0.020 0.980 0.000
H93 Other disorders of ear, not elsewhere classified
0.000 0.981 0.019
H70.1 Chronic mastoiditis
0.000 0.981 0.019
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.019 0.981 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.019 0.981 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.019 0.981 0.000
H69.9 Eustachian tube disorder, unspecified
0.000 0.981 0.019
Y45.0 Opioids and related analgesics
0.019 0.981 0.000
K11.5 Sialolithiasis
0.019 0.981 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.018 0.982 0.000
I44.0 Atrioventricular block, first degree
0.018 0.982 0.000
H93.8 Other specified disorders of ear
0.000 0.982 0.018
Chapter VIII Diseases of the ear and mastoid process
0.000 0.982 0.018
H90-H95 Other disorders of ear
0.000 0.982 0.018
G90.9 Disorder of autonomic nervous system, unspecified
0.017 0.982 0.000
H70.8 Other mastoiditis and related conditions
0.000 0.982 0.018
I05.1 Rheumatic mitral insufficiency
0.018 0.982 0.000
H93.9 Disorder of ear, unspecified
0.000 0.982 0.018
H93.1 Tinnitus
0.000 0.982 0.018
H70.0 Acute mastoiditis
0.000 0.983 0.017
H70.9 Mastoiditis, unspecified
0.000 0.983 0.017
H69.8 Other specified disorders of Eustachian tube
0.000 0.983 0.017
H73 Other disorders of tympanic membrane
0.000 0.983 0.017
H70.2 Petrositis
0.000 0.983 0.017
G93.8 Other specified disorders of brain
0.016 0.983 0.000
H69.0 Patulous Eustachian tube
0.000 0.983 0.016
H66.3 Other chronic suppurative otitis media
0.000 0.984 0.016
K11.2 Sialoadenitis
0.016 0.984 0.000
K11.1 Hypertrophy of salivary gland
0.016 0.984 0.000
H91.1 Presbycusis
0.000 0.985 0.015
I44 Atrioventricular and left bundle-branch block
0.015 0.985 0.000
H66.0 Acute suppurative otitis media
0.000 0.985 0.015
H93.2 Other abnormal auditory perceptions
0.000 0.985 0.015
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.985 0.014
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.985 0.014
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.985 0.014
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.985 0.014
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.985 0.014
K11.4 Fistula of salivary gland
0.014 0.985 0.000
K11.0 Atrophy of salivary gland
0.014 0.985 0.000
H68.0 Eustachian salpingitis
0.000 0.986 0.014
H91 Other hearing loss
0.000 0.986 0.014
H93.0 Degenerative and vascular disorders of ear
0.000 0.986 0.014
H90 Conductive and sensorineural hearing loss
0.000 0.986 0.014
H68.1 Obstruction of Eustachian tube
0.000 0.986 0.014
G94.1 Hydrocephalus in neoplastic disease
0.013 0.986 0.001
D12.2 Ascending colon
0.000 0.986 0.014
H93.3 Disorders of acoustic nerve
0.000 0.986 0.013
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.986 0.013
K11.7 Disturbances of salivary secretion
0.013 0.987 0.000
H66.9 Otitis media, unspecified
0.000 0.987 0.013
G97.9 Postprocedural disorder of nervous system, unspecified
0.013 0.987 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.013 0.987 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.013 0.987 0.000
K11.3 Abscess of salivary gland
0.013 0.987 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.987 0.013
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.987 0.013
H73.0 Acute myringitis
0.000 0.987 0.013
G97.1 Other reaction to spinal and lumbar puncture
0.012 0.988 0.000
I44.4 Left anterior fascicular block
0.012 0.988 0.000
H60-H62 Diseases of external ear
0.000 0.988 0.012
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.988 0.012
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.988 0.012
H73.1 Chronic myringitis
0.000 0.988 0.012
I44.3 Other and unspecified atrioventricular block
0.012 0.988 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.989 0.011
I44.5 Left posterior fascicular block
0.011 0.989 0.000
H71 Cholesteatoma of middle ear
0.000 0.989 0.011
H90.3 Sensorineural hearing loss, bilateral
0.000 0.989 0.011
H90.0 Conductive hearing loss, bilateral
0.000 0.989 0.011
H91.0 Ototoxic hearing loss
0.000 0.990 0.010
K11.9 Disease of salivary gland, unspecified
0.010 0.990 0.000
H91.2 Sudden idiopathic hearing loss
0.000 0.990 0.010
S52.10 Fracture of upper end of radius (closed)
0.010 0.990 0.000
I44.6 Other and unspecified fascicular block
0.010 0.990 0.000
I05-I09 Chronic rheumatic heart diseases
0.010 0.990 0.000
G93.6 Cerebral oedema
0.008 0.990 0.002
H91.8 Other specified hearing loss
0.000 0.990 0.010
H61 Other disorders of external ear
0.000 0.990 0.010
H94.8 Other specified disorders of ear in diseases classified elsewhere
0.000 0.990 0.009
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere
0.000 0.990 0.009
G97.0 Cerebrospinal fluid leak from spinal puncture
0.009 0.991 0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.991 0.009
H80-H83 Diseases of inner ear
0.000 0.991 0.009
G25.8 Other specified extrapyramidal and movement disorders
0.009 0.991 0.000
I06 Rheumatic aortic valve diseases
0.009 0.991 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.991 0.008
H61.0 Perichondritis of external ear
0.000 0.991 0.009
I07 Rheumatic tricuspid valve diseases
0.008 0.991 0.000
H91.3 Deaf mutism, not elsewhere classified
0.000 0.992 0.008
H90.5 Sensorineural hearing loss, unspecified
0.000 0.992 0.008
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.000 0.992 0.008
H95.8 Other postprocedural disorders of ear and mastoid process
0.000 0.992 0.008
H73.8 Other specified disorders of tympanic membrane
0.000 0.992 0.008
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.000 0.992 0.008
I69.3 Sequelae of cerebral infarction
0.008 0.992 0.000
H61.9 Disorder of external ear, unspecified
0.000 0.992 0.008
I06.0 Rheumatic aortic stenosis
0.008 0.992 0.000
S22.40 Multiple fractures of ribs (closed)
0.000 0.992 0.008
H74 Other disorders of middle ear and mastoid
0.000 0.992 0.008
G20 Parkinson's disease
0.000 0.992 0.008
I07.1 Tricuspid insufficiency
0.008 0.992 0.000
H90.2 Conductive hearing loss, unspecified
0.000 0.993 0.007
H92 Otalgia and effusion of ear
0.000 0.993 0.007
I44.2 Atrioventricular block, complete
0.007 0.993 0.000
G97.8 Other postprocedural disorders of nervous system
0.006 0.993 0.001
I69 Sequelae of cerebrovascular disease
0.007 0.993 0.000
H61.3 Acquired stenosis of external ear canal
0.000 0.993 0.007
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.007 0.993 0.000
H61.2 Impacted cerumen
0.000 0.993 0.007
I09 Other rheumatic heart diseases
0.007 0.993 0.000
Z50.2 Alcohol rehabilitation
0.007 0.993 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.007 0.993 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.007 0.993 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.993 0.007
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.993 0.006
H61.8 Other specified disorders of external ear
0.000 0.993 0.007
G24.9 Dystonia, unspecified
0.000 0.993 0.007
I06.8 Other rheumatic aortic valve diseases
0.006 0.993 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.006 0.993 0.000
H81 Disorders of vestibular function
0.000 0.993 0.007
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.994 0.006
H62.8 Other disorders of external ear in diseases classified elsewhere
0.000 0.994 0.006
H62.4 Otitis externa in other diseases classified elsewhere
0.000 0.994 0.006
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
H62.2 Otitis externa in mycoses
0.000 0.994 0.006
H62.1 Otitis externa in viral diseases classified elsewhere
0.000 0.994 0.006
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.994 0.006
I07.9 Tricuspid valve disease, unspecified
0.006 0.994 0.000
I07.8 Other tricuspid valve diseases
0.006 0.994 0.000
I07.2 Tricuspid stenosis with insufficiency
0.006 0.994 0.000
I07.0 Tricuspid stenosis
0.006 0.994 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.006 0.994 0.000
G24 Dystonia
0.000 0.994 0.006
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.006 0.994 0.000
G20-G26 Extrapyramidal and movement disorders
0.001 0.994 0.006
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.006 0.994 0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere
0.000 0.994 0.006
H60 Otitis externa
0.000 0.994 0.006
I06.1 Rheumatic aortic insufficiency
0.006 0.994 0.000
H74.1 Adhesive middle ear disease
0.000 0.994 0.006
H61.1 Non-infective disorders of pinna
0.000 0.994 0.006
Z43.2 Attention to ileostomy
0.000 0.994 0.006
H95.1 Other disorders following mastoidectomy
0.000 0.994 0.006
I61 Intracerebral haemorrhage
0.006 0.994 0.000
G24.8 Other dystonia
0.000 0.994 0.006
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.994 0.006
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.006 0.994 0.000
Z63.4 Disappearance and death of family member
0.006 0.994 0.000
I60-I69 Cerebrovascular diseases
0.006 0.994 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.006 0.994 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.006 0.994 0.000
I60 Subarachnoid haemorrhage
0.005 0.995 0.000
I62 Other nontraumatic intracranial haemorrhage
0.005 0.995 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.005 0.995 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.005 0.995 0.000
H81.2 Vestibular neuronitis
0.000 0.995 0.005
H65 Nonsuppurative otitis media
0.000 0.995 0.005
H81.8 Other disorders of vestibular function
0.000 0.995 0.005
H60.5 Acute otitis externa, non-infective
0.000 0.995 0.005
H81.1 Benign paroxysmal vertigo
0.000 0.995 0.005
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.005 0.995 0.000
I09.8 Other specified rheumatic heart diseases
0.005 0.995 0.000
I09.2 Chronic rheumatic pericarditis
0.005 0.995 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.005 0.995 0.000
I09.0 Rheumatic myocarditis
0.005 0.995 0.000
H92.2 Otorrhagia
0.000 0.995 0.005
D62 Acute posthaemorrhagic anaemia
0.005 0.995 0.000
Z63 Other problems related to primary support group, including family circumstances
0.005 0.995 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.005 0.995 0.000
H74.0 Tympanosclerosis
0.000 0.995 0.005
H80 Otosclerosis
0.000 0.995 0.005
H81.3 Other peripheral vertigo
0.000 0.995 0.005
H83 Other diseases of inner ear
0.000 0.995 0.005
Z61 Problems related to negative life events in childhood
0.005 0.995 0.000
G23 Other degenerative diseases of basal ganglia
0.000 0.995 0.005
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group
0.005 0.995 0.000
H60.2 Malignant otitis externa
0.000 0.995 0.005
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.005 0.995 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.005 0.995 0.000
S52.1 Fracture of upper end of radius
0.005 0.995 0.000
G25 Other extrapyramidal and movement disorders
0.001 0.995 0.004
G24.3 Spasmodic torticollis
0.000 0.995 0.005
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.005 0.995 0.000
H81.9 Disorder of vestibular function, unspecified
0.000 0.995 0.005
G24.4 Idiopathic orofacial dystonia
0.000 0.995 0.004
G24.2 Idiopathic nonfamilial dystonia
0.000 0.995 0.004
G24.0 Drug-induced dystonia
0.000 0.995 0.004
H60.3 Other infective otitis externa
0.000 0.995 0.005
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.001 0.995 0.004
G22 Parkinsonism in diseases classified elsewhere
0.001 0.995 0.004
Z59 Problems related to housing and economic circumstances
0.005 0.995 0.000
G24.1 Idiopathic familial dystonia
0.000 0.995 0.004
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.005 0.995 0.000
Z61.6 Problems related to alleged physical abuse of child
0.005 0.995 0.000
H81.4 Vertigo of central origin
0.000 0.995 0.005
Z56.0 Unemployment, unspecified
0.005 0.995 0.000
Z56 Problems related to employment and unemployment
0.005 0.995 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.005 0.995 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.995 0.004
I69.1 Sequelae of intracerebral haemorrhage
0.005 0.995 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.005 0.995 0.000
I09.9 Rheumatic heart disease, unspecified
0.004 0.995 0.000
H83.9 Disease of inner ear, unspecified
0.000 0.995 0.004
I60.8 Other subarachnoid haemorrhage
0.004 0.995 0.000
H60.0 Abscess of external ear
0.000 0.995 0.004
I65.1 Occlusion and stenosis of basilar artery
0.004 0.996 0.000
Z56.6 Other physical and mental strain related to work
0.004 0.996 0.000
D60-D64 Aplastic and other anaemias
0.004 0.996 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.004 0.996 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.004 0.996 0.000
G21 Secondary Parkinsonism
0.001 0.996 0.004
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.004 0.996 0.000
H60.4 Cholesteatoma of external ear
0.000 0.996 0.004
I66.3 Occlusion and stenosis of cerebellar arteries
0.004 0.996 0.000
Z63.5 Disruption of family by separation and divorce
0.004 0.996 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.004 0.996 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.004 0.996 0.000
H60.9 Otitis externa, unspecified
0.000 0.996 0.004
I61.6 Intracerebral haemorrhage, multiple localised
0.004 0.996 0.000
I61.8 Other intracerebral haemorrhage
0.004 0.996 0.000
H65.0 Acute serous otitis media
0.000 0.996 0.004
R22.4 Localised swelling, mass and lump, lower limb
0.000 0.996 0.004
Z59.9 Problem relating to housing and economic circumstances, unspecified
0.004 0.996 0.000
S22.4 Multiple fractures of ribs
0.000 0.996 0.004
I60.5 Subarachnoid haemorrhage from vertebral artery
0.004 0.996 0.000
H92.1 Otorrhoea
0.000 0.996 0.004
Z90.0 Acquired absence of part of head and neck
0.000 0.996 0.004
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.996 0.004
Z59.0 Homelessness
0.004 0.996 0.000
Z63.8 Other specified problems related to primary support group
0.004 0.996 0.000
Z95.0 Presence of cardiac pacemaker
0.004 0.996 0.000
I46.9 Cardiac arrest, unspecified
0.004 0.996 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.004 0.996 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.004 0.996 0.000
Z59.8 Other problems relating to housing and economic circumstances
0.004 0.996 0.000
Z59.4 Lack of adequate food
0.004 0.996 0.000
G25.5 Other chorea
0.001 0.996 0.003
N13.3 Other and unspecified hydronephrosis
0.000 0.996 0.004
I44.1 Atrioventricular block, second degree
0.004 0.996 0.000
Z61.8 Other negative life events in childhood
0.004 0.996 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.004 0.996 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.004 0.996 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.004 0.996 0.000
Y45.2 Propionic acid derivatives
0.004 0.996 0.000
Z63.6 Dependent relative needing care at home
0.004 0.996 0.000
Z63.9 Problem related to primary support group, unspecified
0.004 0.996 0.000
Z63.3 Absence of family member
0.004 0.996 0.000
Z63.2 Inadequate family support
0.004 0.996 0.000
Z63.1 Problems in relationship with parents and in-laws
0.004 0.996 0.000
G25.2 Other specified forms of tremor
0.001 0.996 0.003
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.996 0.003
H80.8 Other otosclerosis
0.000 0.996 0.004
H80.2 Cochlear otosclerosis
0.000 0.996 0.004
H80.1 Otosclerosis involving oval window, obliterative
0.000 0.996 0.004
I68.0 Cerebral amyloid angiopathy
0.004 0.996 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.004 0.996 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.996 0.003
G23.3 Multiple system atrophy, cerebellar type
0.000 0.996 0.003
G23.2 Striatonigral degeneration
0.000 0.996 0.003
G23.0 Hallervorden-Spatz disease
0.000 0.996 0.003
H83.2 Labyrinthine dysfunction
0.000 0.996 0.004
H83.1 Labyrinthine fistula
0.000 0.996 0.004
Z61.9 Negative life events in childhood, unspecified
0.004 0.996 0.000
Z61.7 Personal frightening experience in childhood
0.004 0.996 0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group
0.004 0.996 0.000
Z61.3 Events resulting in loss of self-esteem in childhood
0.004 0.996 0.000
Z61.2 Altered pattern of family relationships in childhood
0.004 0.996 0.000
Z61.1 Removal from home in childhood
0.004 0.996 0.000
Z61.0 Loss of love relationship in childhood
0.004 0.996 0.000
S52.11 Fracture of upper end of radius (open)
0.004 0.996 0.000
I65.2 Occlusion and stenosis of carotid artery
0.004 0.996 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.004 0.996 0.000
H80.0 Otosclerosis involving oval window, nonobliterative
0.000 0.996 0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.004 0.996 0.000
Z63.0 Problems in relationship with spouse or partner
0.004 0.996 0.000
H83.8 Other specified diseases of inner ear
0.000 0.996 0.004
I62.1 Nontraumatic extradural haemorrhage
0.004 0.996 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.001 0.996 0.003
G25.4 Drug-induced chorea
0.001 0.996 0.003
Z59.2 Discord with neighbours, lodgers and landlord
0.004 0.996 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.996 0.003
H83.3 Noise effects on inner ear
0.000 0.996 0.004
Y45.4 Antirheumatics
0.004 0.996 0.000
G25.1 Drug-induced tremor
0.001 0.996 0.003
G25.0 Essential tremor
0.000 0.996 0.003
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.000 0.996 0.004
H60.8 Other otitis externa
0.000 0.996 0.004
Y45.8 Other analgesics and antipyretics
0.004 0.996 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.996 0.004
Z59.7 Insufficient social insurance and welfare support
0.004 0.996 0.000
Z59.6 Low income
0.004 0.996 0.000
Z59.5 Extreme poverty
0.004 0.996 0.000
Z59.3 Problems related to living in residential institution
0.004 0.996 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.004 0.996 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.001 0.996 0.003
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.003 0.996 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.004 0.996 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.004 0.996 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.000 0.996 0.004
H65.1 Other acute nonsuppurative otitis media
0.000 0.996 0.003
H65.2 Chronic serous otitis media
0.000 0.996 0.004
Z56.7 Other and unspecified problems related to employment
0.003 0.996 0.000
Z56.5 Uncongenial work
0.003 0.996 0.000
Z56.4 Discord with boss and workmates
0.003 0.996 0.000
Z56.2 Threat of job loss
0.003 0.996 0.000
Z56.1 Change of job
0.003 0.996 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.003 0.996 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.003 0.996 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.003 0.996 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.003 0.996 0.000
Z64 Problems related to certain psychosocial circumstances
0.003 0.996 0.000
H92.0 Otalgia
0.000 0.996 0.003
G21.8 Other secondary Parkinsonism
0.001 0.997 0.003
G21.3 Postencephalitic Parkinsonism
0.001 0.997 0.003
G21.2 Secondary Parkinsonism due to other external agents
0.001 0.997 0.003
G21.0 Malignant neuroleptic syndrome
0.001 0.997 0.003
Z62 Other problems related to upbringing
0.003 0.997 0.000
Z55 Problems related to education and literacy
0.003 0.997 0.000
Z43.3 Attention to colostomy
0.000 0.997 0.003
Z59.1 Inadequate housing
0.003 0.997 0.000
H81.0 Meniere's disease
0.000 0.997 0.003
S41.1 Open wound of upper arm
0.000 0.997 0.003
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.003 0.997 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.003 0.997 0.000
G21.9 Secondary Parkinsonism, unspecified
0.001 0.997 0.003
G21.1 Other drug-induced secondary Parkinsonism
0.001 0.997 0.003
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.003 0.997 0.000
Z63.7 Other stressful life events affecting family and household
0.003 0.997 0.000
G25.3 Myoclonus
0.001 0.997 0.003
H60.1 Cellulitis of external ear
0.000 0.997 0.003
S22.41 Multiple fractures of ribs (open)
0.000 0.997 0.003
G21.4 Vascular parkinsonism
0.001 0.997 0.003
Y45.5 4-Aminophenol derivatives
0.003 0.997 0.000
Z65 Problems related to other psychosocial circumstances
0.003 0.997 0.000
Z90.5 Acquired absence of kidney
0.000 0.997 0.003
M77.91 Enthesopathy, unspecified (Shoulder region)
0.000 0.997 0.003
I60.4 Subarachnoid haemorrhage from basilar artery
0.003 0.997 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.003 0.997 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.003 0.997 0.000
Z58 Problems related to physical environment
0.003 0.997 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.003 0.997 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.003 0.997 0.000
D55-D59 Haemolytic anaemias
0.003 0.997 0.000
Z56.3 Stressful work schedule
0.003 0.997 0.000
G50.0 Trigeminal neuralgia
0.003 0.997 0.000
A49.1 Streptococcal infection, unspecified
0.000 0.997 0.003
Z64.0 Problems related to unwanted pregnancy
0.003 0.997 0.000
Z64.4 Discord with counsellors
0.003 0.997 0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful
0.003 0.997 0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful
0.003 0.997 0.000
Z64.1 Problems related to multiparity
0.003 0.997 0.000
G24.5 Blepharospasm
0.001 0.997 0.002
A49.8 Other bacterial infections of unspecified site
0.000 0.997 0.003
Z55.9 Problems relating to education and literacy, unspecified
0.003 0.997 0.000
Z55.8 Other problems relating to education and literacy
0.003 0.997 0.000
Z55.4 Educational maladjustment and discord with teachers and classmates
0.003 0.997 0.000
Z55.3 Underachievement in school
0.003 0.997 0.000
Z55.2 Failed examinations
0.003 0.997 0.000
Z55.1 Schooling unavailable and unattainable
0.003 0.997 0.000
Z55.0 Illiteracy and low-level literacy
0.003 0.997 0.000
Z62.9 Problem related to upbringing, unspecified
0.003 0.997 0.000
Z62.8 Other specified problems related to upbringing
0.003 0.997 0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing
0.003 0.997 0.000
Z62.5 Other problems related to neglect in upbringing
0.003 0.997 0.000
Z62.4 Emotional neglect of child
0.003 0.997 0.000
Z62.3 Hostility towards and scapegoating of child
0.003 0.997 0.000
Z62.2 Institutional upbringing
0.003 0.997 0.000
Z62.1 Parental overprotection
0.003 0.997 0.000
Z62.0 Inadequate parental supervision and control
0.003 0.997 0.000
D60.8 Other acquired pure red cell aplasias
0.003 0.997 0.000
D60.1 Transient acquired pure red cell aplasia
0.003 0.997 0.000
D60.0 Chronic acquired pure red cell aplasia
0.003 0.997 0.000
Z43.5 Attention to cyctostomy
0.000 0.997 0.003
Z43 Attention to artificial openings
0.000 0.997 0.003
K01.1 Impacted teeth
0.003 0.997 0.000
R44.3 Hallucinations, unspecified
0.003 0.997 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.002 0.997 0.000
M77.9 Enthesopathy, unspecified
0.000 0.997 0.003
Z65.9 Problem related to unspecified psychosocial circumstances
0.002 0.997 0.000
Z65.5 Exposure to disaster, war and other hostilities
0.002 0.997 0.000
Z65.4 Victim of crime and terrorism
0.002 0.997 0.000
Z65.2 Problems related to release from prison
0.002 0.997 0.000
Z65.1 Imprisonment and other incarceration
0.002 0.997 0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment
0.002 0.997 0.000
M85.8 Other specified disorders of bone density and structure
0.003 0.997 0.000
Z58.5 Exposure to other pollution
0.002 0.997 0.000
M77.92 Enthesopathy, unspecified (Upper arm)
0.000 0.997 0.003
Z65.8 Other specified problems related to psychosocial circumstances
0.002 0.997 0.000
H74.4 Polyp of middle ear
0.001 0.997 0.002
Z65.3 Problems related to other legal circumstances
0.002 0.997 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.002 0.997 0.000
S41.0 Open wound of shoulder
0.000 0.997 0.002
D64 Other anaemias
0.003 0.997 0.000
G82.2 Paraplegia, unspecified
0.002 0.997 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.002 0.997 0.000
Z58.9 Problem related to physical environment, unspecified
0.002 0.998 0.000
Z58.6 Inadequate drinking-water supply
0.002 0.998 0.000
Z58.4 Exposure to radiation
0.002 0.998 0.000
Z58.3 Exposure to soil pollution
0.002 0.998 0.000
Z58.2 Exposure to water pollution
0.002 0.998 0.000
Z58.0 Exposure to noise
0.002 0.998 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.002 0.998 0.000
D57 Sickle-cell disorders
0.002 0.998 0.000
D55 Anaemia due to enzyme disorders
0.002 0.998 0.000
D61 Other aplastic anaemias
0.002 0.998 0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)
0.000 0.998 0.002
G50 Disorders of trigeminal nerve
0.002 0.998 0.000
D31.3 Choroid
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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