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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78873708
log Bayes Factor = 28.1642
Chromosome 16   position 7,408,842  (GRCh37) Explore rs78873708 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
D64 Other anaemias
0.998 0.002 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
D64.9 Anaemia, unspecified
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
I60-I69 Cerebrovascular diseases
0.994 0.006 0.000
I73 Other peripheral vascular diseases
0.993 0.007 0.000
A30-A49 Other bacterial diseases
0.992 0.008 0.000
Z51 Other medical care
0.991 0.009 0.000
Z92 Personal history of medical treatment
0.990 0.010 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.987 0.013 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
I77 Other disorders of arteries and arterioles
0.984 0.016 0.000
E10-E14 Diabetes mellitus
0.983 0.017 0.000
Chapter X Diseases of the respiratory system
0.982 0.018 0.000
Z50 Care involving use of rehabilitation procedures
0.980 0.020 0.000
Z42 Follow-up care involving plastic surgery
0.979 0.021 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
A41 Other septicaemia
0.976 0.024 0.000
Z51.3 Blood transfusion without reported diagnosis
0.975 0.025 0.000
I20-I25 Ischaemic heart diseases
0.972 0.028 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
M75 Shoulder lesions
0.970 0.030 0.000
Chapter II Neoplasms
0.966 0.034 0.000
I51 Complications and ill-defined descriptions of heart disease
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.965 0.035 0.000
E70-E90 Metabolic disorders
0.964 0.036 0.000
J09-J18 Influenza and pneumonia
0.963 0.037 0.000
I25 Chronic ischaemic heart disease
0.963 0.037 0.000
J40-J47 Chronic lower respiratory diseases
0.957 0.043 0.000
D70 Agranulocytosis
0.956 0.044 0.000
I73.9 Peripheral vascular disease, unspecified
0.956 0.044 0.000
Z51.1 Chemotherapy session for neoplasm
0.953 0.047 0.000
M75.5 Bursitis of shoulder
0.953 0.047 0.000
K40-K46 Hernia
0.953 0.047 0.000
I73.0 Raynaud's syndrome
0.952 0.048 0.000
I67 Other cerebrovascular diseases
0.951 0.049 0.000
J18 Pneumonia, organism unspecified
0.947 0.053 0.000
K42 Umbilical hernia
0.947 0.053 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.946 0.054 0.000
Z94 Transplanted organ and tissue status
0.945 0.055 0.000
I77.1 Stricture of artery
0.945 0.055 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.944 0.056 0.000
I51.7 Cardiomegaly
0.943 0.057 0.000
Z87 Personal history of other diseases and conditions
0.942 0.058 0.000
E14 Unspecified diabetes mellitus
0.941 0.059 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.937 0.063 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.936 0.064 0.000
I44 Atrioventricular and left bundle-branch block
0.936 0.064 0.000
B25-B34 Other viral diseases
0.936 0.064 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.936 0.064 0.000
J18.1 Lobar pneumonia, unspecified
0.934 0.066 0.000
I69 Sequelae of cerebrovascular disease
0.933 0.067 0.000
Z49 Care involving dialysis
0.930 0.070 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.930 0.070 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.930 0.070 0.000
Z95.2 Presence of prosthetic heart valve
0.924 0.076 0.000
J43 Emphysema
0.924 0.076 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.920 0.080 0.000
Z53.9 Procedure not carried out, unspecified reason
0.920 0.080 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.919 0.081 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.915 0.085 0.000
M05-M14 Inflammatory polyarthropathies
0.913 0.087 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.912 0.088 0.000
C51-C58 Malignant neoplasms of female genital organs
0.911 0.089 0.000
Z87.1 Personal history of diseases of the digestive system
0.907 0.093 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.904 0.096 0.000
Z87.0 Personal history of diseases of the respiratory system
0.901 0.099 0.000
J43.9 Emphysema, unspecified
0.900 0.100 0.000
E86 Volume depletion
0.898 0.102 0.000
I71 Aortic aneurysm and dissection
0.897 0.103 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.897 0.103 0.000
I67.8 Other specified cerebrovascular diseases
0.893 0.107 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.891 0.109 0.000
Z95.4 Presence of other heart-valve replacement
0.888 0.112 0.000
E14.9 Without complications
0.888 0.112 0.000
K50-K52 Noninfective enteritis and colitis
0.885 0.115 0.000
I74 Arterial embolism and thrombosis
0.884 0.116 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.884 0.116 0.000
Z50.5 Speech therapy
0.882 0.117 0.000
C56 Malignant neoplasm of ovary
0.882 0.118 0.000
Z94.0 Kidney transplant status
0.880 0.120 0.000
M10 Gout
0.880 0.120 0.000
E20-E35 Disorders of other endocrine glands
0.880 0.120 0.000
I25.1 Atherosclerotic heart disease
0.877 0.123 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.875 0.125 0.000
Chapter XXII Codes for special purposes
0.874 0.126 0.000
I50 Heart failure
0.873 0.127 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.872 0.128 0.000
Z50.0 Cardiac rehabilitation
0.870 0.130 0.000
E83 Disorders of mineral metabolism
0.868 0.132 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.868 0.132 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.865 0.135 0.000
I38 Endocarditis, valve unspecified
0.865 0.135 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.864 0.136 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.863 0.137 0.000
Y43 Primarily systemic agents
0.861 0.139 0.000
I25.2 Old myocardial infarction
0.860 0.140 0.000
I67.1 Cerebral aneurysm, nonruptured
0.858 0.142 0.000
A41.9 Septicaemia, unspecified
0.858 0.142 0.000
M10.9 Gout, unspecified
0.857 0.143 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
K65-K67 Diseases of peritoneum
0.856 0.144 0.000
C92 Myeloid leukaemia
0.855 0.145 0.000
B99-B99 Other infectious diseases
0.854 0.146 0.000
I44.7 Left bundle-branch block, unspecified
0.853 0.147 0.000
E11 Non-insulin-dependent diabetes mellitus
0.851 0.149 0.000
K08 Other disorders of teeth and supporting structures
0.850 0.150 0.000
B34 Viral infection of unspecified site
0.850 0.150 0.000
E65-E68 Obesity and other hyperalimentation
0.848 0.152 0.000
S00-S09 Injuries to the head
0.848 0.152 0.000
R05 Cough
0.845 0.155 0.000
I60 Subarachnoid haemorrhage
0.844 0.156 0.000
Z95.0 Presence of cardiac pacemaker
0.841 0.159 0.000
I51.9 Heart disease, unspecified
0.840 0.160 0.000
A40 Streptococcal septicaemia
0.840 0.160 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.838 0.162 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.838 0.162 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.836 0.164 0.000
Z49.1 Extracorporeal dialysis
0.836 0.164 0.000
H40-H42 Glaucoma
0.834 0.166 0.000
B35-B49 Mycoses
0.834 0.166 0.000
M77 Other enthesopathies
0.834 0.166 0.000
B95-B98 Bacterial, viral and other infectious agents
0.833 0.167 0.000
H53-H54 Visual disturbances and blindness
0.833 0.167 0.000
I05-I09 Chronic rheumatic heart diseases
0.833 0.167 0.000
K43 Ventral hernia
0.832 0.168 0.000
C64-C68 Malignant neoplasms of urinary tract
0.830 0.170 0.000
I50.9 Heart failure, unspecified
0.829 0.171 0.000
I44.2 Atrioventricular block, complete
0.829 0.171 0.000
M10.99 Gout, unspecified (Site unspecified)
0.829 0.171 0.000
W00-W19 Falls
0.826 0.174 0.000
D69 Purpura and other haemorrhagic conditions
0.824 0.176 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.824 0.176 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.822 0.178 0.000
H55-H59 Other disorders of eye and adnexa
0.821 0.179 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.821 0.179 0.000
M75.4 Impingement syndrome of shoulder
0.818 0.182 0.000
D62 Acute posthaemorrhagic anaemia
0.818 0.182 0.000
M40-M43 Deforming dorsopathies
0.817 0.183 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.817 0.183 0.000
E83.5 Disorders of calcium metabolism
0.817 0.183 0.000
I34 Nonrheumatic mitral valve disorders
0.815 0.185 0.000
I69.3 Sequelae of cerebral infarction
0.814 0.186 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.813 0.187 0.000
Z45 Adjustment and management of implanted device
0.812 0.188 0.000
E50-E64 Other nutritional deficiencies
0.812 0.188 0.000
J18.9 Pneumonia, unspecified
0.807 0.193 0.000
J45 Asthma
0.806 0.194 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.805 0.195 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.803 0.197 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.803 0.197 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.802 0.198 0.000
M20-M25 Other joint disorders
0.802 0.198 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.801 0.199 0.000
Z51.8 Other specified medical care
0.801 0.199 0.000
B25 Cytomegaloviral disease
0.797 0.203 0.000
D80-D89 Certain disorders involving the immune mechanism
0.797 0.203 0.000
I77.8 Other specified disorders of arteries and arterioles
0.796 0.204 0.000
M86-M90 Other osteopathies
0.794 0.206 0.000
K90-K93 Other diseases of the digestive system
0.793 0.207 0.000
Z49.0 Preparatory care for dialysis
0.792 0.208 0.000
Y40 Systemic antibiotics
0.791 0.208 0.000
E14.3 With ophthalmic complications
0.791 0.209 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.791 0.209 0.000
R04 Haemorrhage from respiratory passages
0.791 0.209 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.791 0.209 0.000
E13 Other specified diabetes mellitus
0.789 0.211 0.000
Z89 Acquired absence of limb
0.789 0.211 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
M91-M94 Chondropathies
0.788 0.212 0.000
M75.9 Shoulder lesion, unspecified
0.788 0.212 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.785 0.215 0.000
I77.6 Arteritis, unspecified
0.785 0.215 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.784 0.216 0.000
A46 Erysipelas
0.784 0.216 0.000
Y43.3 Other antineoplastic drugs
0.783 0.217 0.000
D72 Other disorders of white blood cells
0.782 0.218 0.000
D50-D53 Nutritional anaemias
0.781 0.219 0.000
V40-V49 Car occupant injured in transport accident
0.781 0.219 0.000
Z29 Need for other prophylactic measures
0.780 0.220 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.779 0.221 0.000
A49 Bacterial infection of unspecified site
0.778 0.222 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.776 0.224 0.000
I70 Atherosclerosis
0.776 0.224 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.776 0.224 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.774 0.226 0.000
I24 Other acute ischaemic heart diseases
0.772 0.228 0.000
B65-B83 Helminthiases
0.772 0.228 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.772 0.228 0.000
Z99.2 Dependence on renal dialysis
0.771 0.229 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.770 0.230 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.770 0.230 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.769 0.231 0.000
K50 Crohn's disease [regional enteritis]
0.769 0.231 0.000
E85 Amyloidosis
0.768 0.232 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.768 0.232 0.000
M72 Fibroblastic disorders
0.767 0.233 0.000
Z80 Family history of malignant neoplasm
0.767 0.233 0.000
B34.9 Viral infection, unspecified
0.767 0.233 0.000
I42 Cardiomyopathy
0.765 0.235 0.000
R79 Other abnormal findings of blood chemistry
0.763 0.237 0.000
H30-H36 Disorders of choroid and retina
0.763 0.237 0.000
Z22 Carrier of infectious disease
0.762 0.238 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.239 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.761 0.239 0.000
S01 Open wound of head
0.759 0.241 0.000
J11 Influenza, virus not identified
0.759 0.241 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.758 0.242 0.000
J46 Status asthmaticus
0.757 0.243 0.000
K66 Other disorders of peritoneum
0.756 0.244 0.000
C92.1 Chronic myeloid leukaemia
0.756 0.244 0.000
I74.5 Embolism and thrombosis of iliac artery
0.754 0.246 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.754 0.246 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.754 0.246 0.000
Chapter VI Diseases of the nervous system
0.754 0.246 0.000
I63 Cerebral infarction
0.753 0.247 0.000
Z92.0 Personal history of contraception
0.752 0.248 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.751 0.249 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.750 0.250 0.000
B99 Other and unspecified infectious diseases
0.749 0.251 0.000
Z92.8 Personal history of other medical treatment
0.749 0.251 0.000
S00 Superficial injury of head
0.749 0.251 0.000
R04.0 Epistaxis
0.749 0.251 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.747 0.253 0.000
I78 Diseases of capillaries
0.747 0.253 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.747 0.253 0.000
E10 Insulin-dependent diabetes mellitus
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.746 0.254 0.000
Z94.8 Other transplanted organ and tissue status
0.744 0.256 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.744 0.256 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.743 0.257 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.741 0.259 0.000
H40 Glaucoma
0.741 0.259 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.741 0.259 0.000
J45.9 Asthma, unspecified
0.741 0.259 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.740 0.260 0.000
E66 Obesity
0.740 0.260 0.000
K51 Ulcerative colitis
0.738 0.262 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.738 0.262 0.000
I35 Nonrheumatic aortic valve disorders
0.738 0.262 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.736 0.264 0.000
A80-A89 Viral infections of the central nervous system
0.735 0.264 0.000
E87.6 Hypokalaemia
0.734 0.266 0.000
I30 Acute pericarditis
0.733 0.267 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.733 0.267 0.000
C67 Malignant neoplasm of bladder
0.732 0.268 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.732 0.268 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.732 0.268 0.000
D55-D59 Haemolytic anaemias
0.732 0.268 0.000
Z51.2 Other chemotherapy
0.731 0.269 0.000
K92 Other diseases of digestive system
0.730 0.270 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.730 0.270 0.000
K50.9 Crohn's disease, unspecified
0.730 0.270 0.000
C32 Malignant neoplasm of larynx
0.729 0.271 0.000
K10 Other diseases of jaws
0.728 0.272 0.000
Z94.4 Liver transplant status
0.728 0.272 0.000
R26 Abnormalities of gait and mobility
0.727 0.273 0.000
Z51.9 Medical care, unspecified
0.727 0.273 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.727 0.273 0.000
H53 Visual disturbances
0.726 0.274 0.000
D68 Other coagulation defects
0.725 0.275 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.724 0.275 0.000
M00-M03 Infectious arthropathies
0.724 0.276 0.000
C92.0 Acute myeloid leukaemia
0.724 0.276 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.723 0.277 0.000
K08.3 Retained dental root
0.723 0.277 0.000
J95-J99 Other diseases of the respiratory system
0.721 0.279 0.000
I44.3 Other and unspecified atrioventricular block
0.721 0.279 0.000
I25.5 Ischaemic cardiomyopathy
0.720 0.280 0.000
M75.1 Rotator cuff syndrome
0.720 0.280 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.720 0.280 0.000
I95 Hypotension
0.719 0.281 0.000
K92.1 Melaena
0.719 0.281 0.000
I07 Rheumatic tricuspid valve diseases
0.718 0.282 0.000
M71 Other bursopathies
0.718 0.282 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.718 0.282 0.000
D69.6 Thrombocytopenia, unspecified
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I67.2 Cerebral atherosclerosis
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
D64.8 Other specified anaemias
0.716 0.284 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.284 0.000
D64.3 Other sideroblastic anaemias
0.716 0.284 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.284 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.284 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.284 0.000
M10.96 Gout, unspecified (Lower leg)
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
Z95.3 Presence of xenogenic heart valve
0.714 0.286 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.713 0.287 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.713 0.287 0.000
E27 Other disorders of adrenal gland
0.713 0.287 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.712 0.288 0.000
I73.8 Other specified peripheral vascular diseases
0.712 0.288 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.712 0.288 0.000
A48 Other bacterial diseases, not elsewhere classified
0.711 0.288 0.000
A44 Bartonellosis
0.711 0.288 0.000
A43 Nocardiosis
0.711 0.288 0.000
A42 Actinomycosis
0.711 0.288 0.000
A39 Meningococcal infection
0.711 0.288 0.000
A37 Whooping cough
0.711 0.288 0.000
A36 Diphtheria
0.711 0.288 0.000
A32 Listeriosis
0.711 0.288 0.000
A31 Infection due to other mycobacteria
0.711 0.288 0.000
A30 Leprosy [Hansen's disease]
0.711 0.288 0.000
A38 Scarlet fever
0.711 0.288 0.000
A35 Other tetanus
0.711 0.288 0.000
A34 Obstetrical tetanus
0.711 0.288 0.000
A33 Tetanus neonatorum
0.711 0.288 0.000
D51 Vitamin B12 deficiency anaemia
0.711 0.289 0.000
Z51.6 Desensitisation to allergens
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.289 0.000
J60-J70 Lung diseases due to external agents
0.711 0.289 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.710 0.290 0.000
Z92.9 Personal history of medical treatment, unspecified
0.710 0.290 0.000
Z92.5 Personal history of rehabilitation measures
0.710 0.290 0.000
S02 Fracture of skull and facial bones
0.710 0.290 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.710 0.290 0.000
E11.5 With peripheral circulatory complications
0.708 0.292 0.000
J42 Unspecified chronic bronchitis
0.708 0.292 0.000
M06 Other rheumatoid arthritis
0.707 0.293 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
I44.1 Atrioventricular block, second degree
0.706 0.294 0.000
I77.5 Necrosis of artery
0.706 0.294 0.000
I77.4 Coeliac artery compression syndrome
0.706 0.294 0.000
I77.3 Arterial fibromuscular dysplasia
0.706 0.294 0.000
I77.2 Rupture of artery
0.706 0.294 0.000
I77.0 Arteriovenous fistula, acquired
0.706 0.294 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.295 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.705 0.295 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.705 0.295 0.000
H40.1 Primary open-angle glaucoma
0.705 0.295 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.295 0.000
K00 Disorders of tooth development and eruption
0.704 0.296 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.704 0.296 0.000
R29.6 Tendency to fall, not elsewhere classified
0.704 0.296 0.000
E11.9 Without complications
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.296 0.000
I34.0 Mitral (valve) insufficiency
0.703 0.297 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.703 0.297 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.703 0.297 0.000
R01 Cardiac murmurs and other cardiac sounds
0.703 0.297 0.000
Z50.6 Orthoptic training
0.703 0.297 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.703 0.297 0.000
Z50.3 Drug rehabilitation
0.703 0.297 0.000
I62 Other nontraumatic intracranial haemorrhage
0.702 0.298 0.000
I72 Other aneurysm
0.702 0.298 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.702 0.298 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.702 0.298 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.702 0.298 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.702 0.298 0.000
I45 Other conduction disorders
0.702 0.298 0.000
E87.0 Hyperosmolality and hypernatraemia
0.702 0.298 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.298 0.000
M11 Other crystal arthropathies
0.701 0.299 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.701 0.299 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.700 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.700 0.300 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.700 0.300 0.000
D74 Methaemoglobinaemia
0.700 0.300 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.700 0.300 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.700 0.300 0.000
U80 Agent resistant to penicillin and related antibiotics
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.300 0.000
Y10-Y34 Event of undetermined intent
0.699 0.300 0.000
Y00-Y09 Assault
0.699 0.300 0.000
X85-X99 Assault
0.699 0.300 0.000
X50-X57 Overexertion, travel and privation
0.699 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.699 0.300 0.000
X30-X39 Exposure to forces of nature
0.699 0.300 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.300 0.000
X10-X19 Contact with heat and hot substances
0.699 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.300 0.000
W75-W84 Other accidental threats to breathing
0.699 0.300 0.000
W65-W74 Accidental drowning and submersion
0.699 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.300 0.000
V95-V97 Air and space transport accidents
0.699 0.300 0.000
V90-V94 Water transport accidents
0.699 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.300 0.000
H57 Other disorders of eye and adnexa
0.699 0.300 0.000
A41.4 Septicaemia due to anaerobes
0.699 0.300 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.699 0.300 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.699 0.300 0.000
B25.9 Cytomegaloviral disease, unspecified
0.698 0.302 0.000
I23 Certain current complications following acute myocardial infarction
0.697 0.303 0.000
E29 Testicular dysfunction
0.697 0.303 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.696 0.304 0.000
M75.8 Other shoulder lesions
0.695 0.304 0.000
M77.1 Lateral epicondylitis
0.695 0.305 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.695 0.305 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
I51.6 Cardiovascular disease, unspecified
0.692 0.308 0.000
I51.5 Myocardial degeneration
0.692 0.308 0.000
I51.4 Myocarditis, unspecified
0.692 0.308 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.692 0.308 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.692 0.308 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.692 0.308 0.000
I51.0 Cardiac septal defect, acquired
0.692 0.308 0.000
Z50.1 Other physical therapy
0.692 0.308 0.000
B15-B19 Viral hepatitis
0.691 0.308 0.000
J40 Bronchitis, not specified as acute or chronic
0.691 0.308 0.000
J44 Other chronic obstructive pulmonary disease
0.691 0.309 0.000
A41.8 Other specified septicaemia
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
Z95.1 Presence of aortocoronary bypass graft
0.691 0.309 0.000
J17 Pneumonia in diseases classified elsewhere
0.690 0.309 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.690 0.309 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.690 0.309 0.000
J12 Viral pneumonia, not elsewhere classified
0.690 0.309 0.000
J10 Influenza due to identified influenza virus
0.690 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.690 0.309 0.000
J09 Influenza due to certain identified influenza virus
0.690 0.309 0.000
I25.6 Silent myocardial ischaemia
0.690 0.309 0.000
I25.4 Coronary artery aneurysm
0.690 0.309 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.690 0.309 0.000
Z54 Convalescence
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
K41 Femoral hernia
0.690 0.310 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
Y43.0 Antiallergic and antiemetic drugs
0.689 0.311 0.000
J84 Other interstitial pulmonary diseases
0.689 0.311 0.000
Z52 Donors of organs and tissues
0.688 0.311 0.000
Z46 Fitting and adjustment of other devices
0.688 0.311 0.000
E87.2 Acidosis
0.687 0.313 0.000
A40.0 Septicaemia due to streptococcus, group A
0.687 0.313 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.686 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.314 0.000
J41 Simple and mucopurulent chronic bronchitis
0.686 0.314 0.000
H43-H45 Disorders of vitreous body and globe
0.686 0.314 0.000
S06 Intracranial injury
0.685 0.315 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.685 0.315 0.000
K66.0 Peritoneal adhesions
0.685 0.315 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.684 0.315 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
I25.3 Aneurysm of heart
0.684 0.316 0.000
W07 Fall involving chair
0.683 0.317 0.000
K45 Other abdominal hernia
0.683 0.317 0.000
V10-V19 Pedal cyclist injured in transport accident
0.683 0.317 0.000
R07 Pain in throat and chest
0.683 0.317 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.682 0.318 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.682 0.318 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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