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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112817022
log Bayes Factor = 21.0666
Chromosome 16   position 22,274,136  (GRCh37) Explore rs112817022 on Ensembl!
Variant rs112817022 is part of Cluster X0201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter II Neoplasms
0.993 0.007 0.000
M45-M49 Spondylopathies
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.987 0.013 0.000
G40-G47 Episodic and paroxysmal disorders
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
B95-B98 Bacterial, viral and other infectious agents
0.981 0.019 0.000
D00-D09 In situ neoplasms
0.980 0.020 0.000
I20-I25 Ischaemic heart diseases
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.978 0.022 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.975 0.025 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.974 0.026 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.974 0.026 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.974 0.026 0.000
Z85 Personal history of malignant neoplasm
0.973 0.027 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.965 0.035 0.000
Chapter VIII Diseases of the ear and mastoid process
0.964 0.036 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.964 0.036 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.962 0.038 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.962 0.038 0.000
M47 Spondylosis
0.960 0.040 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.960 0.040 0.000
I25 Chronic ischaemic heart disease
0.958 0.042 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.958 0.042 0.000
I95 Hypotension
0.953 0.047 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.950 0.050 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.950 0.050 0.000
E87.5 Hyperkalaemia
0.949 0.051 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.947 0.053 0.000
W00-W19 Falls
0.947 0.053 0.000
M48 Other spondylopathies
0.946 0.054 0.000
M47.9 Spondylosis, unspecified
0.945 0.055 0.000
H53-H54 Visual disturbances and blindness
0.944 0.056 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.944 0.056 0.000
G40 Epilepsy
0.943 0.057 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.942 0.058 0.000
I95.9 Hypotension, unspecified
0.941 0.059 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.941 0.059 0.000
I60-I69 Cerebrovascular diseases
0.940 0.060 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.939 0.061 0.000
M40-M43 Deforming dorsopathies
0.936 0.064 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.936 0.064 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.936 0.064 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.931 0.069 0.000
H90-H95 Other disorders of ear
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.922 0.078 0.000
C50-C50 Malignant neoplasm of breast
0.920 0.080 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.919 0.081 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.915 0.085 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.915 0.085 0.000
I44 Atrioventricular and left bundle-branch block
0.914 0.086 0.000
H04 Disorders of lachrymal system
0.914 0.086 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.912 0.088 0.000
M80-M85 Disorders of bone density and structure
0.909 0.091 0.000
M48.0 Spinal stenosis
0.907 0.093 0.000
H65-H75 Diseases of middle ear and mastoid
0.904 0.096 0.000
J09-J18 Influenza and pneumonia
0.903 0.097 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.902 0.098 0.000
G47 Sleep disorders
0.901 0.099 0.000
I26 Pulmonary embolism
0.901 0.099 0.000
D04 Carcinoma in situ of skin
0.897 0.103 0.000
E83 Disorders of mineral metabolism
0.897 0.103 0.000
Z92 Personal history of medical treatment
0.896 0.104 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.895 0.105 0.000
J30-J39 Other diseases of upper respiratory tract
0.892 0.108 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.891 0.109 0.000
E87.2 Acidosis
0.890 0.110 0.000
M43 Other deforming dorsopathies
0.890 0.110 0.000
Z42 Follow-up care involving plastic surgery
0.889 0.111 0.000
D05 Carcinoma in situ of breast
0.888 0.112 0.000
J40-J47 Chronic lower respiratory diseases
0.887 0.113 0.000
W19 Unspecified fall
0.884 0.116 0.000
I50 Heart failure
0.884 0.116 0.000
C71 Malignant neoplasm of brain
0.883 0.117 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.881 0.119 0.000
H30-H36 Disorders of choroid and retina
0.876 0.124 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.871 0.129 0.000
C50 Malignant neoplasm of breast
0.869 0.131 0.000
I61 Intracerebral haemorrhage
0.868 0.132 0.000
S70-S79 Injuries to the hip and thigh
0.867 0.133 0.000
J00-J06 Acute upper respiratory infections
0.867 0.133 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.865 0.135 0.000
Z49 Care involving dialysis
0.864 0.136 0.000
C50.9 Breast, unspecified
0.863 0.137 0.000
Y43 Primarily systemic agents
0.863 0.137 0.000
I21 Acute myocardial infarction
0.862 0.138 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.862 0.138 0.000
I46 Cardiac arrest
0.862 0.138 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.858 0.142 0.000
E83.4 Disorders of magnesium metabolism
0.856 0.144 0.000
H72 Perforation of tympanic membrane
0.855 0.145 0.000
H54 Blindness and low vision
0.855 0.145 0.000
T90 Sequelae of injuries of head
0.854 0.146 0.000
D03 Melanoma in situ
0.853 0.147 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.851 0.149 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.851 0.149 0.000
Z50 Care involving use of rehabilitation procedures
0.850 0.150 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.850 0.150 0.000
Z45 Adjustment and management of implanted device
0.850 0.150 0.000
I89.0 Lymphoedema, not elsewhere classified
0.850 0.150 0.000
Z96 Presence of other functional implants
0.850 0.150 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.848 0.152 0.000
M48.09 Spinal stenosis (Site unspecified)
0.846 0.154 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.846 0.154 0.000
I62 Other nontraumatic intracranial haemorrhage
0.846 0.154 0.000
I34 Nonrheumatic mitral valve disorders
0.843 0.157 0.000
G91 Hydrocephalus
0.842 0.158 0.000
I85 Oesophageal varices
0.838 0.162 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.838 0.162 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.838 0.162 0.000
I50.1 Left ventricular failure
0.837 0.163 0.000
M43.1 Spondylolisthesis
0.836 0.164 0.000
I80 Phlebitis and thrombophlebitis
0.835 0.165 0.000
H53 Visual disturbances
0.835 0.165 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.834 0.166 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.833 0.167 0.000
C45 Mesothelioma
0.833 0.167 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.832 0.168 0.000
F10.0 Acute intoxication
0.830 0.170 0.000
G30-G32 Other degenerative diseases of the nervous system
0.830 0.170 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.829 0.171 0.000
Z57 Occupational exposure to risk-factors
0.829 0.171 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.828 0.172 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.827 0.173 0.000
H04.2 Epiphora
0.826 0.174 0.000
M51 Other intervertebral disk disorders
0.825 0.174 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.824 0.176 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.823 0.177 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.822 0.178 0.000
G20-G26 Extrapyramidal and movement disorders
0.822 0.178 0.000
Z40 Prophylactic surgery
0.821 0.179 0.000
F10.1 Harmful use
0.821 0.179 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.820 0.180 0.000
Z96.8 Presence of other specified functional implants
0.815 0.185 0.000
M60-M63 Disorders of muscles
0.815 0.185 0.000
M54 Dorsalgia
0.814 0.186 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.814 0.186 0.000
C64-C68 Malignant neoplasms of urinary tract
0.814 0.186 0.000
I60 Subarachnoid haemorrhage
0.814 0.186 0.000
G95 Other diseases of spinal cord
0.813 0.187 0.000
J46 Status asthmaticus
0.813 0.187 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.813 0.187 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.812 0.188 0.000
M20-M25 Other joint disorders
0.812 0.188 0.000
J35 Chronic diseases of tonsils and adenoids
0.811 0.189 0.000
H91 Other hearing loss
0.811 0.189 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.810 0.190 0.000
H92 Otalgia and effusion of ear
0.809 0.191 0.000
I25.4 Coronary artery aneurysm
0.809 0.191 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.807 0.193 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.805 0.195 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.805 0.195 0.000
M05-M14 Inflammatory polyarthropathies
0.804 0.196 0.000
I44.7 Left bundle-branch block, unspecified
0.803 0.197 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.803 0.197 0.000
V80-V89 Other land transport accidents
0.801 0.199 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.801 0.199 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.800 0.200 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.800 0.200 0.000
D05.1 Intraductal carcinoma in situ
0.798 0.202 0.000
C71.9 Brain, unspecified
0.797 0.203 0.000
H55-H59 Other disorders of eye and adnexa
0.795 0.205 0.000
H10-H13 Disorders of conjunctiva
0.795 0.205 0.000
T90.9 Sequelae of unspecified injury of head
0.795 0.205 0.000
T43.2 Other and unspecified antidepressants
0.795 0.205 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.794 0.206 0.000
S60-S69 Injuries to the wrist and hand
0.794 0.206 0.000
J47 Bronchiectasis
0.793 0.207 0.000
I45 Other conduction disorders
0.792 0.208 0.000
G40.9 Epilepsy, unspecified
0.792 0.208 0.000
I46.0 Cardiac arrest with successful resuscitation
0.790 0.210 0.000
M48.06 Spinal stenosis (Lumbar region)
0.789 0.211 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.788 0.212 0.000
X50-X57 Overexertion, travel and privation
0.788 0.212 0.000
J00 Acute nasopharyngitis [common cold]
0.787 0.213 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.787 0.213 0.000
D04.5 Skin of trunk
0.786 0.214 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.785 0.215 0.000
H34 Retinal vascular occlusions
0.785 0.215 0.000
Z49.0 Preparatory care for dialysis
0.785 0.215 0.000
E73 Lactose intolerance
0.784 0.216 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
I22 Subsequent myocardial infarction
0.784 0.216 0.000
Z97 Presence of other devices
0.783 0.217 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.783 0.217 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.781 0.219 0.000
M84 Disorders of continuity of bone
0.781 0.219 0.000
G47.3 Sleep apnoea
0.779 0.221 0.000
Y52 Agents primarily affecting the cardiovascular system
0.777 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.778 0.222 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.777 0.223 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.776 0.224 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.775 0.225 0.000
F30-F39 Mood [affective] disorders
0.775 0.225 0.000
M46 Other inflammatory spondylopathies
0.774 0.226 0.000
J14 Pneumonia due to Haemophilus influenzae
0.773 0.227 0.000
E20-E35 Disorders of other endocrine glands
0.773 0.227 0.000
D06 Carcinoma in situ of cervix uteri
0.773 0.227 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.772 0.228 0.000
M06 Other rheumatoid arthritis
0.772 0.228 0.000
Z94 Transplanted organ and tissue status
0.772 0.228 0.000
F10.2 Dependence syndrome
0.771 0.229 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.770 0.230 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.769 0.231 0.000
M54.3 Sciatica
0.769 0.231 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.768 0.232 0.000
I05-I09 Chronic rheumatic heart diseases
0.767 0.233 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.767 0.233 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.766 0.234 0.000
T92 Sequelae of injuries of upper limb
0.765 0.235 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.765 0.235 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.764 0.236 0.000
G93 Other disorders of brain
0.762 0.238 0.000
Z92.3 Personal history of irradiation
0.762 0.238 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.761 0.239 0.000
Y43.3 Other antineoplastic drugs
0.761 0.239 0.000
I51 Complications and ill-defined descriptions of heart disease
0.761 0.239 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.760 0.240 0.000
H93 Other disorders of ear, not elsewhere classified
0.760 0.240 0.000
I69 Sequelae of cerebrovascular disease
0.760 0.240 0.000
Z84 Family history of other conditions
0.759 0.241 0.000
E83.5 Disorders of calcium metabolism
0.759 0.241 0.000
I85.9 Oesophageal varices without bleeding
0.758 0.242 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.758 0.242 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.758 0.242 0.000
I31 Other diseases of pericardium
0.757 0.243 0.000
I27 Other pulmonary heart diseases
0.757 0.243 0.000
T87 Complications peculiar to reattachment and amputation
0.752 0.247 0.000
S70 Superficial injury of hip and thigh
0.752 0.248 0.000
T82.3 Mechanical complication of other vascular grafts
0.752 0.248 0.000
E87.6 Hypokalaemia
0.751 0.249 0.000
W19.2 School, other institution and public administrative area
0.751 0.249 0.000
I38 Endocarditis, valve unspecified
0.749 0.251 0.000
I34.0 Mitral (valve) insufficiency
0.748 0.252 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.748 0.252 0.000
M06.9 Rheumatoid arthritis, unspecified
0.748 0.252 0.000
M86-M90 Other osteopathies
0.746 0.253 0.000
I25.2 Old myocardial infarction
0.746 0.254 0.000
Z57.2 Occupational exposure to dust
0.746 0.254 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.745 0.255 0.000
I44.2 Atrioventricular block, complete
0.744 0.256 0.000
G47.8 Other sleep disorders
0.743 0.257 0.000
W19.4 Street and highway
0.743 0.257 0.000
C71.1 Frontal lobe
0.743 0.257 0.000
V40-V49 Car occupant injured in transport accident
0.743 0.257 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.742 0.258 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.742 0.258 0.000
Z89 Acquired absence of limb
0.741 0.259 0.000
I44.1 Atrioventricular block, second degree
0.741 0.259 0.000
Y57 Other and unspecified drugs and medicaments
0.741 0.259 0.000
G40.8 Other epilepsy
0.740 0.259 0.000
S10-S19 Injuries to the neck
0.740 0.259 0.000
I30 Acute pericarditis
0.740 0.260 0.000
I44.3 Other and unspecified atrioventricular block
0.740 0.260 0.000
Y40 Systemic antibiotics
0.739 0.260 0.000
I82 Other venous embolism and thrombosis
0.739 0.261 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.739 0.261 0.000
M43.6 Torticollis
0.738 0.262 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.738 0.262 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.738 0.262 0.000
C69 Malignant neoplasm of eye and adnexa
0.737 0.263 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.737 0.263 0.000
J95-J99 Other diseases of the respiratory system
0.736 0.264 0.000
Z45.2 Adjustment and management of vascular access device
0.735 0.265 0.000
H34.8 Other retinal vascular occlusions
0.734 0.266 0.000
J35.1 Hypertrophy of tonsils
0.733 0.267 0.000
F80-F89 Disorders of psychological development
0.733 0.267 0.000
I81 Portal vein thrombosis
0.733 0.267 0.000
W18 Other fall on same level
0.732 0.268 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.731 0.269 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.731 0.269 0.000
H91.9 Hearing loss, unspecified
0.730 0.270 0.000
F41 Other anxiety disorders
0.730 0.270 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.730 0.270 0.000
T86 Failure and rejection of transplanted organs and tissues
0.729 0.271 0.000
Z95.1 Presence of aortocoronary bypass graft
0.729 0.271 0.000
I25.5 Ischaemic cardiomyopathy
0.729 0.271 0.000
W17 Other fall from one level to another
0.728 0.271 0.000
Z54 Convalescence
0.728 0.272 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.728 0.272 0.000
E87.7 Fluid overload
0.728 0.272 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.727 0.273 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.727 0.273 0.000
G44 Other headache syndromes
0.727 0.273 0.000
W06 Fall involving bed
0.726 0.274 0.000
F11 Mental and behavioural disorders due to use of opioids
0.726 0.274 0.000
C45.0 Mesothelioma of pleura
0.726 0.274 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.724 0.276 0.000
C65 Malignant neoplasm of renal pelvis
0.721 0.279 0.000
D04.4 Skin of scalp and neck
0.721 0.279 0.000
I86 Varicose veins of other sites
0.721 0.279 0.000
B65-B83 Helminthiases
0.721 0.279 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.721 0.279 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.721 0.279 0.000
J42 Unspecified chronic bronchitis
0.720 0.280 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.720 0.280 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.720 0.280 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.720 0.280 0.000
M54.1 Radiculopathy
0.720 0.280 0.000
J11 Influenza, virus not identified
0.720 0.280 0.000
M24 Other specific joint derangements
0.720 0.280 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.719 0.281 0.000
D05.0 Lobular carcinoma in situ
0.719 0.281 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.719 0.281 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.718 0.282 0.000
Y48 Anaesthetics and therapeutic gases
0.718 0.282 0.000
B35-B49 Mycoses
0.718 0.282 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.717 0.282 0.000
M54.39 Sciatica (Site unspecified)
0.717 0.283 0.000
H69 Other disorders of Eustachian tube
0.717 0.283 0.000
S00-S09 Injuries to the head
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.284 0.000
M82 Osteoporosis in diseases classified elsewhere
0.715 0.285 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.715 0.285 0.000
H53.0 Amblyopia ex anopsia
0.714 0.286 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
H43-H45 Disorders of vitreous body and globe
0.714 0.286 0.000
T42.4 Benzodiazepines
0.713 0.287 0.000
Z60 Problems related to social environment
0.713 0.287 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
W10 Fall on and from stairs and steps
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.712 0.288 0.000
D04.6 Skin of upper limb, including shoulder
0.711 0.289 0.000
E10-E14 Diabetes mellitus
0.711 0.289 0.000
I36 Nonrheumatic tricuspid valve disorders
0.711 0.289 0.000
M49 Spondylopathies in diseases classified elsewhere
0.711 0.289 0.000
M47.8 Other spondylosis
0.711 0.289 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.710 0.290 0.000
M31 Other necrotising vasculopathies
0.710 0.290 0.000
H73 Other disorders of tympanic membrane
0.709 0.291 0.000
C50.4 Upper-outer quadrant of breast
0.709 0.291 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.708 0.292 0.000
H54.4 Blindness, one eye
0.708 0.292 0.000
G45.4 Transient global amnesia
0.708 0.292 0.000
E85 Amyloidosis
0.708 0.292 0.000
E84 Cystic fibrosis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
E87.4 Mixed disorder of acid-base balance
0.708 0.292 0.000
E87.3 Alkalosis
0.708 0.292 0.000
H50 Other strabismus
0.707 0.293 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.707 0.293 0.000
T82.1 Mechanical complication of cardiac electronic device
0.706 0.293 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
Y44 Agents primarily affecting blood constituents
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.705 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
C71.8 Overlapping lesion of brain
0.704 0.296 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.704 0.296 0.000
Z92.8 Personal history of other medical treatment
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.297 0.000
H54.7 Unspecified visual loss
0.703 0.297 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.703 0.297 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.703 0.297 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.703 0.297 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.703 0.297 0.000
J02 Acute pharyngitis
0.702 0.298 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.702 0.298 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.298 0.000
G90 Disorders of autonomic nervous system
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.298 0.000
C45.9 Mesothelioma, unspecified
0.701 0.299 0.000
M81 Osteoporosis without pathological fracture
0.701 0.299 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.701 0.299 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.700 0.300 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.700 0.300 0.000
Z64 Problems related to certain psychosocial circumstances
0.700 0.300 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.700 0.300 0.000
I47 Paroxysmal tachycardia
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.700 0.300 0.000
T91 Sequelae of injuries of neck and trunk
0.699 0.301 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.699 0.301 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.699 0.301 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.699 0.301 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.698 0.302 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.698 0.302 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.698 0.302 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.698 0.302 0.000
M91-M94 Chondropathies
0.698 0.302 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.698 0.302 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.698 0.302 0.000
F10.3 Withdrawal state
0.696 0.304 0.000
C77.3 Axillary and upper limb lymph nodes
0.696 0.304 0.000
W07 Fall involving chair
0.696 0.304 0.000
H70 Mastoiditis and related conditions
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.695 0.304 0.000
Z50.0 Cardiac rehabilitation
0.695 0.305 0.000
I61.8 Other intracerebral haemorrhage
0.695 0.305 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.694 0.306 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.694 0.306 0.000
H21 Other disorders of iris and ciliary body
0.693 0.307 0.000
W13 Fall from, out of or through building or structure
0.692 0.307 0.000
T43.9 Psychotropic drug, unspecified
0.692 0.308 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
T43.6 Psychostimulants with abuse potential
0.692 0.308 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.692 0.308 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.692 0.308 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
M80 Osteoporosis with pathological fracture
0.692 0.308 0.000
W19.3 Sports and athletics area
0.691 0.308 0.000
W19.9 Unspecified place
0.692 0.308 0.000
T85.2 Mechanical complication of intraocular lens
0.691 0.309 0.000
G03 Meningitis due to other and unspecified causes
0.691 0.309 0.000
T51 Toxic effect of alcohol
0.690 0.310 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.690 0.310 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.690 0.310 0.000
G92 Toxic encephalopathy
0.690 0.310 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
D04.3 Skin of other and unspecified parts of face
0.689 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.689 0.311 0.000
M51.2 Other specified intervertebral disk displacement
0.689 0.311 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.688 0.312 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.688 0.312 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.688 0.312 0.000
Z47 Other orthopaedic follow-up care
0.688 0.312 0.000
H92.1 Otorrhoea
0.688 0.312 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.687 0.313 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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