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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117312671
log Bayes Factor = 24.8436
Chromosome 16   position 67,936,863  (GRCh37) Explore rs117312671 on Ensembl!
Variant rs117312671 is part of Cluster X0268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.994 0.006 0.000
R50-R69 General symptoms and signs
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
J40-J47 Chronic lower respiratory diseases
0.992 0.008 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.988 0.012 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.988 0.012 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.987 0.013 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.985 0.015 0.000
R07 Pain in throat and chest
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
R07.3 Other chest pain
0.983 0.017 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.983 0.017 0.000
I10-I15 Hypertensive diseases
0.981 0.019 0.000
I83 Varicose veins of lower extremities
0.978 0.022 0.000
J90-J94 Other diseases of pleura
0.977 0.023 0.000
J44 Other chronic obstructive pulmonary disease
0.975 0.025 0.000
Z51 Other medical care
0.974 0.026 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.973 0.027 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.969 0.031 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.969 0.031 0.000
I10 Essential (primary) hypertension
0.969 0.031 0.000
M80-M85 Disorders of bone density and structure
0.967 0.033 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.966 0.034 0.000
N83.2 Other and unspecified ovarian cysts
0.963 0.037 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.963 0.037 0.000
T81 Complications of procedures, not elsewhere classified
0.960 0.040 0.000
N73 Other female pelvic inflammatory diseases
0.959 0.041 0.000
R59 Enlarged lymph nodes
0.955 0.045 0.000
M81 Osteoporosis without pathological fracture
0.950 0.050 0.000
J90 Pleural effusion, not elsewhere classified
0.949 0.051 0.000
Z51.1 Chemotherapy session for neoplasm
0.948 0.052 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.948 0.052 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.945 0.055 0.000
Chapter VII Diseases of the eye and adnexa
0.944 0.056 0.000
K40-K46 Hernia
0.942 0.058 0.000
Chapter XX External causes of morbidity and mortality
0.941 0.059 0.000
C15-C26 Malignant neoplasms of digestive organs
0.940 0.060 0.000
M81.9 Osteoporosis, unspecified
0.938 0.062 0.000
Chapter V Mental and behavioural disorders
0.936 0.064 0.000
N73.6 Female pelvic peritoneal adhesions
0.933 0.067 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.931 0.069 0.000
R12 Heartburn
0.931 0.069 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.929 0.071 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.927 0.073 0.000
R18 Ascites
0.925 0.075 0.000
N80 Endometriosis
0.922 0.078 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.918 0.082 0.000
R11 Nausea and vomiting
0.911 0.089 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.904 0.096 0.000
R59.0 Localised enlarged lymph nodes
0.903 0.097 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.900 0.100 0.000
Chapter VI Diseases of the nervous system
0.899 0.101 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.898 0.102 0.000
Z51.5 Palliative care
0.894 0.106 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.894 0.106 0.000
R02 Gangrene, not elsewhere classified
0.893 0.107 0.000
J43 Emphysema
0.890 0.110 0.000
N84 Polyp of female genital tract
0.889 0.111 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.888 0.112 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.879 0.121 0.000
J09-J18 Influenza and pneumonia
0.879 0.121 0.000
H40-H42 Glaucoma
0.874 0.126 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.873 0.127 0.000
A30-A49 Other bacterial diseases
0.872 0.128 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.870 0.130 0.000
C80 Malignant neoplasm without specification of site
0.869 0.131 0.000
S20-S29 Injuries to the thorax
0.866 0.134 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.863 0.137 0.000
M70-M79 Other soft tissue disorders
0.862 0.138 0.000
R55 Syncope and collapse
0.861 0.139 0.000
C18 Malignant neoplasm of colon
0.860 0.140 0.000
K81 Cholecystitis
0.859 0.141 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.859 0.141 0.000
Z43 Attention to artificial openings
0.859 0.141 0.000
K44 Diaphragmatic hernia
0.856 0.144 0.000
N17-N19 Renal failure
0.856 0.144 0.000
N97 Female infertility
0.855 0.145 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.852 0.148 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.851 0.149 0.000
R68 Other general symptoms and signs
0.851 0.149 0.000
I84 Haemorrhoids
0.850 0.150 0.000
D00-D09 In situ neoplasms
0.849 0.151 0.000
M20-M25 Other joint disorders
0.849 0.151 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.847 0.153 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.847 0.153 0.000
K90-K93 Other diseases of the digestive system
0.847 0.153 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.845 0.155 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.843 0.157 0.000
N60-N64 Disorders of breast
0.842 0.158 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.841 0.159 0.000
S32 Fracture of lumbar spine and pelvis
0.841 0.159 0.000
K86 Other diseases of pancreas
0.841 0.159 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.837 0.163 0.000
I85 Oesophageal varices
0.837 0.163 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.835 0.165 0.000
Z51.3 Blood transfusion without reported diagnosis
0.835 0.165 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.835 0.165 0.000
R54 Senility
0.833 0.167 0.000
N80.8 Other endometriosis
0.833 0.167 0.000
S80-S89 Injuries to the knee and lower leg
0.831 0.169 0.000
N89 Other noninflammatory disorders of vagina
0.831 0.169 0.000
F30-F39 Mood [affective] disorders
0.830 0.170 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.829 0.171 0.000
H40 Glaucoma
0.825 0.175 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.825 0.175 0.000
R07.4 Chest pain, unspecified
0.825 0.175 0.000
J40 Bronchitis, not specified as acute or chronic
0.820 0.180 0.000
N10-N16 Renal tubulo-interstitial diseases
0.819 0.180 0.000
J43.9 Emphysema, unspecified
0.817 0.183 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.817 0.183 0.000
R59.1 Generalised enlarged lymph nodes
0.817 0.183 0.000
R17 Unspecified jaundice
0.816 0.184 0.000
N76 Other inflammation of vagina and vulva
0.813 0.187 0.000
K43 Ventral hernia
0.813 0.187 0.000
N71 Inflammatory disease of uterus, except cervix
0.811 0.189 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.810 0.190 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.191 0.000
N81 Female genital prolapse
0.809 0.191 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.809 0.191 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.804 0.196 0.000
B35-B49 Mycoses
0.803 0.197 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.803 0.197 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.802 0.198 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.801 0.199 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.799 0.201 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.798 0.202 0.000
M25 Other joint disorders, not elsewhere classified
0.797 0.203 0.000
N80.3 Endometriosis of pelvic peritoneum
0.795 0.205 0.000
C01 Malignant neoplasm of base of tongue
0.795 0.205 0.000
R61 Hyperhidrosis
0.795 0.205 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.794 0.206 0.000
I81 Portal vein thrombosis
0.794 0.206 0.000
K65-K67 Diseases of peritoneum
0.794 0.206 0.000
H40.9 Glaucoma, unspecified
0.792 0.208 0.000
H53-H54 Visual disturbances and blindness
0.791 0.209 0.000
N84.1 Polyp of cervix uteri
0.790 0.210 0.000
K81.9 Cholecystitis, unspecified
0.790 0.210 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.790 0.210 0.000
D70 Agranulocytosis
0.789 0.211 0.000
N19 Unspecified renal failure
0.788 0.212 0.000
M85 Other disorders of bone density and structure
0.788 0.212 0.000
J18 Pneumonia, organism unspecified
0.787 0.213 0.000
C80.9 Malignant neoplasm, unspecified
0.784 0.216 0.000
M75 Shoulder lesions
0.784 0.216 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.782 0.218 0.000
Chapter VIII Diseases of the ear and mastoid process
0.782 0.218 0.000
N75 Diseases of Bartholin's gland
0.781 0.219 0.000
R60 Oedema, not elsewhere classified
0.780 0.220 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.779 0.221 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.779 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
I05-I09 Chronic rheumatic heart diseases
0.776 0.224 0.000
K70-K77 Diseases of liver
0.776 0.224 0.000
B25-B34 Other viral diseases
0.776 0.224 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.772 0.228 0.000
T81.9 Unspecified complication of procedure
0.772 0.228 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.772 0.228 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
J94 Other pleural conditions
0.768 0.232 0.000
J95-J99 Other diseases of the respiratory system
0.768 0.232 0.000
I87 Other disorders of veins
0.766 0.234 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.236 0.000
N70 Salpingitis and oophoritis
0.764 0.236 0.000
Y83.6 Removal of other organ (partial) (total)
0.764 0.236 0.000
R69 Unknown and unspecified causes of morbidity
0.763 0.237 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.763 0.237 0.000
S70-S79 Injuries to the hip and thigh
0.763 0.237 0.000
J00-J06 Acute upper respiratory infections
0.761 0.239 0.000
M65-M68 Disorders of synovium and tendon
0.761 0.239 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.761 0.239 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.761 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.761 0.239 0.000
S32.0 Fracture of lumbar vertebra
0.760 0.240 0.000
R05 Cough
0.759 0.241 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.759 0.241 0.000
N00-N08 Glomerular diseases
0.758 0.242 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.758 0.242 0.000
J60-J70 Lung diseases due to external agents
0.758 0.242 0.000
D60-D64 Aplastic and other anaemias
0.757 0.243 0.000
F32 Depressive episode
0.757 0.243 0.000
I11 Hypertensive heart disease
0.756 0.243 0.000
R50 Fever of unknown origin
0.756 0.244 0.000
N95 Menopausal and other perimenopausal disorders
0.755 0.245 0.000
A41 Other septicaemia
0.754 0.246 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.754 0.246 0.000
N97.9 Female infertility, unspecified
0.753 0.247 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.752 0.248 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.752 0.248 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.751 0.249 0.000
J93 Pneumothorax
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.750 0.250 0.000
D75 Other diseases of blood and blood-forming organs
0.750 0.250 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.749 0.251 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.748 0.252 0.000
D06 Carcinoma in situ of cervix uteri
0.748 0.252 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.747 0.253 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.747 0.253 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.747 0.253 0.000
I84.2 Internal haemorrhoids without complication
0.746 0.254 0.000
R14 Flatulence and related conditions
0.746 0.254 0.000
T66-T78 Other and unspecified effects of external causes
0.746 0.254 0.000
S00-S09 Injuries to the head
0.746 0.254 0.000
Z53.0 Procedure not carried out because of contraindication
0.745 0.255 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.743 0.257 0.000
N83.0 Follicular cyst of ovary
0.742 0.257 0.000
R41.0 Disorientation, unspecified
0.741 0.259 0.000
R19.5 Other fecal abnormalities
0.741 0.259 0.000
R47-R49 Symptoms and signs involving speech and voice
0.740 0.260 0.000
H00 Hordeolum and chalazion
0.739 0.260 0.000
K07 Dentofacial anomalies [including malocclusion]
0.739 0.261 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.739 0.261 0.000
J45 Asthma
0.738 0.262 0.000
N83.1 Corpus luteum cyst
0.738 0.262 0.000
Z50 Care involving use of rehabilitation procedures
0.737 0.262 0.000
B15-B19 Viral hepatitis
0.736 0.264 0.000
R94 Abnormal results of function studies
0.735 0.265 0.000
Z45 Adjustment and management of implanted device
0.734 0.266 0.000
Z51.0 Radiotherapy session
0.733 0.267 0.000
C78.2 Secondary malignant neoplasm of pleura
0.733 0.267 0.000
R41.3 Other amnesia
0.733 0.267 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.733 0.267 0.000
Z51.8 Other specified medical care
0.731 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.731 0.269 0.000
D72 Other disorders of white blood cells
0.730 0.270 0.000
Z49 Care involving dialysis
0.730 0.270 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.730 0.270 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.728 0.272 0.000
K85 Acute pancreatitis
0.728 0.272 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.728 0.272 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.727 0.273 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.727 0.273 0.000
M81.98 Osteoporosis, unspecified (Other)
0.726 0.274 0.000
I85.9 Oesophageal varices without bleeding
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.724 0.276 0.000
I84.4 External haemorrhoids with other complications
0.724 0.276 0.000
N80.1 Endometriosis of ovary
0.724 0.276 0.000
C51-C58 Malignant neoplasms of female genital organs
0.723 0.277 0.000
D45 Polycythaemia vera
0.722 0.278 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.721 0.279 0.000
C18.2 Ascending colon
0.720 0.280 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.719 0.281 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.718 0.281 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.718 0.282 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.717 0.282 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.717 0.283 0.000
Z48 Other surgical follow-up care
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.717 0.283 0.000
N99-N99 Other disorders of the genitourinary system
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
N98 Complications associated with artificial fertilisation
0.715 0.284 0.000
N91 Absent, scanty and rare menstruation
0.715 0.284 0.000
N82 Fistulae involving female genital tract
0.715 0.284 0.000
N96 Habitual aborter
0.715 0.284 0.000
Y83.8 Other surgical procedures
0.715 0.285 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.715 0.285 0.000
J92 Pleural plaque
0.714 0.286 0.000
Z43.2 Attention to ileostomy
0.714 0.286 0.000
N60 Benign mammary dysplasia
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
C18.9 Colon, unspecified
0.713 0.287 0.000
D73 Diseases of spleen
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
I88 Nonspecific lymphadenitis
0.713 0.287 0.000
I86 Varicose veins of other sites
0.713 0.287 0.000
I82 Other venous embolism and thrombosis
0.713 0.287 0.000
M86-M90 Other osteopathies
0.712 0.288 0.000
N63 Unspecified lump in breast
0.712 0.288 0.000
R15 Faecal incontinence
0.712 0.288 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.712 0.288 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.711 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.288 0.000
J41 Simple and mucopurulent chronic bronchitis
0.711 0.289 0.000
J46 Status asthmaticus
0.711 0.289 0.000
J42 Unspecified chronic bronchitis
0.711 0.289 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.711 0.289 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.709 0.290 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.709 0.290 0.000
G30-G32 Other degenerative diseases of the nervous system
0.708 0.292 0.000
M75.1 Rotator cuff syndrome
0.708 0.292 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.708 0.292 0.000
N83.7 Haematoma of broad ligament
0.708 0.292 0.000
N83.6 Haematosalpinx
0.708 0.292 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.708 0.292 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.708 0.292 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.708 0.292 0.000
K83 Other diseases of biliary tract
0.707 0.293 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.707 0.293 0.000
F43 Reaction to severe stress, and adjustment disorders
0.706 0.294 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.706 0.294 0.000
R07.1 Chest pain on breathing
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
C20 Malignant neoplasm of rectum
0.706 0.294 0.000
K40 Inguinal hernia
0.705 0.294 0.000
K86.8 Other specified diseases of pancreas
0.705 0.295 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
Z54 Convalescence
0.705 0.295 0.000
Z52 Donors of organs and tissues
0.705 0.295 0.000
Z44 Fitting and adjustment of external prosthetic device
0.705 0.295 0.000
K42 Umbilical hernia
0.705 0.295 0.000
F32.9 Depressive episode, unspecified
0.705 0.295 0.000
H02 Other disorders of eyelid
0.704 0.296 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.704 0.296 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.704 0.296 0.000
I15 Secondary hypertension
0.703 0.297 0.000
I13 Hypertensive heart and renal disease
0.703 0.297 0.000
I84.5 External haemorrhoids without complication
0.703 0.297 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.703 0.297 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.703 0.297 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.702 0.298 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.702 0.298 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.702 0.298 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.701 0.298 0.000
N81.2 Incomplete uterovaginal prolapse
0.701 0.299 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.701 0.299 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.701 0.299 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.700 0.300 0.000
J91 Pleural effusion in conditions classified elsewhere
0.700 0.300 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.698 0.302 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.698 0.302 0.000
Z51.9 Medical care, unspecified
0.698 0.302 0.000
Z51.6 Desensitisation to allergens
0.698 0.302 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.698 0.302 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.697 0.302 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.697 0.302 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.697 0.302 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.697 0.303 0.000
H10-H13 Disorders of conjunctiva
0.697 0.303 0.000
Chapter XXII Codes for special purposes
0.697 0.303 0.000
M40-M43 Deforming dorsopathies
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
R13 Dysphagia
0.696 0.304 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.695 0.305 0.000
N72 Inflammatory disease of cervix uteri
0.694 0.306 0.000
G40-G47 Episodic and paroxysmal disorders
0.694 0.306 0.000
M84 Disorders of continuity of bone
0.693 0.307 0.000
M83 Adult osteomalacia
0.693 0.307 0.000
M82 Osteoporosis in diseases classified elsewhere
0.693 0.307 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.693 0.307 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.693 0.307 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.692 0.307 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.692 0.307 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.692 0.307 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.693 0.307 0.000
N84.0 Polyp of corpus uteri
0.692 0.308 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.692 0.308 0.000
M80 Osteoporosis with pathological fracture
0.691 0.309 0.000
J18.9 Pneumonia, unspecified
0.690 0.310 0.000
I60-I69 Cerebrovascular diseases
0.688 0.311 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.688 0.312 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.688 0.312 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.688 0.312 0.000
C16 Malignant neoplasm of stomach
0.688 0.312 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.687 0.312 0.000
N73.5 Female pelvic peritonitis, unspecified
0.687 0.312 0.000
N73.4 Female chronic pelvic peritonitis
0.687 0.312 0.000
N73.3 Female acute pelvic peritonitis
0.687 0.312 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.687 0.312 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.687 0.312 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.687 0.312 0.000
R52 Pain, not elsewhere classified
0.687 0.313 0.000
A49 Bacterial infection of unspecified site
0.686 0.314 0.000
C77.5 Intrapelvic lymph nodes
0.685 0.315 0.000
H01 Other inflammation of eyelid
0.685 0.315 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.683 0.317 0.000
K86.2 Cyst of pancreas
0.683 0.317 0.000
V20-V29 Motorcycle rider injured in transport accident
0.682 0.318 0.000
M81.8 Other osteoporosis
0.681 0.319 0.000
M81.6 Localised osteoporosis [Lequesne]
0.681 0.319 0.000
M81.5 Idiopathic osteoporosis
0.681 0.319 0.000
M81.4 Drug-induced osteoporosis
0.681 0.319 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.681 0.319 0.000
M81.2 Osteoporosis of disuse
0.681 0.319 0.000
M81.1 Postoophorectomy osteoporosis
0.681 0.319 0.000
M81.0 Postmenopausal osteoporosis
0.681 0.319 0.000
C25 Malignant neoplasm of pancreas
0.681 0.319 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.681 0.319 0.000
M25.8 Other specified joint disorders
0.680 0.320 0.000
I80 Phlebitis and thrombophlebitis
0.680 0.320 0.000
C91 Lymphoid leukaemia
0.680 0.320 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.680 0.320 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.680 0.320 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.679 0.321 0.000
M25.5 Pain in joint
0.679 0.321 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
R63 Symptoms and signs concerning food and fluid intake
0.678 0.322 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.678 0.322 0.000
D80-D89 Certain disorders involving the immune mechanism
0.678 0.322 0.000
D55-D59 Haemolytic anaemias
0.678 0.322 0.000
Z40 Prophylactic surgery
0.677 0.323 0.000
C79 Secondary malignant neoplasm of other sites
0.677 0.323 0.000
N81.8 Other female genital prolapse
0.677 0.323 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.677 0.323 0.000
K46 Unspecified abdominal hernia
0.675 0.324 0.000
K45 Other abdominal hernia
0.675 0.324 0.000
K41 Femoral hernia
0.675 0.324 0.000
N81.9 Female genital prolapse, unspecified
0.675 0.324 0.000
K09 Cysts of oral region, not elsewhere classified
0.675 0.325 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.675 0.325 0.000
D06.9 Cervix, unspecified
0.675 0.325 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.675 0.325 0.000
K90 Intestinal malabsorption
0.675 0.325 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.674 0.325 0.000
Y35-Y36 Legal intervention and operations of war
0.674 0.325 0.000
Y10-Y34 Event of undetermined intent
0.674 0.325 0.000
Y00-Y09 Assault
0.674 0.325 0.000
X85-X99 Assault
0.674 0.325 0.000
X60-X84 Intentional self-harm
0.674 0.325 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.674 0.325 0.000
X50-X57 Overexertion, travel and privation
0.674 0.325 0.000
X30-X39 Exposure to forces of nature
0.674 0.325 0.000
X20-X29 Contact with venomous animals and plants
0.674 0.325 0.000
X10-X19 Contact with heat and hot substances
0.674 0.325 0.000
X00-X09 Exposure to smoke, fire and flames
0.674 0.325 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.674 0.325 0.000
W75-W84 Other accidental threats to breathing
0.674 0.325 0.000
W65-W74 Accidental drowning and submersion
0.674 0.325 0.000
W50-W64 Exposure to animate mechanical forces
0.674 0.325 0.000
V98-V99 Other and unspecified transport accidents
0.674 0.325 0.000
V95-V97 Air and space transport accidents
0.674 0.325 0.000
V90-V94 Water transport accidents
0.674 0.325 0.000
V80-V89 Other land transport accidents
0.674 0.325 0.000
V70-V79 Bus occupant injured in transport accident
0.674 0.325 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.674 0.325 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.674 0.325 0.000
V40-V49 Car occupant injured in transport accident
0.674 0.325 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.674 0.325 0.000
V01-V09 Pedestrian injured in transport accident
0.674 0.325 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.674 0.326 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.674 0.326 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.674 0.326 0.000
C21 Malignant neoplasm of anus and anal canal
0.674 0.326 0.000
C17 Malignant neoplasm of small intestine
0.674 0.326 0.000
C23 Malignant neoplasm of gallbladder
0.674 0.326 0.000
T51 Toxic effect of alcohol
0.674 0.326 0.000
Z41 Procedures for purposes other than remedying health state
0.674 0.326 0.000
I84.6 Residual haemorrhoidal skin tags
0.673 0.327 0.000
N92 Excessive, frequent and irregular menstruation
0.673 0.327 0.000
C15 Malignant neoplasm of oesophagus
0.673 0.327 0.000
R59.9 Enlarged lymph nodes, unspecified
0.672 0.328 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.672 0.328 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.672 0.328 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.672 0.328 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.672 0.328 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.672 0.328 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.672 0.328 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.672 0.328 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.672 0.328 0.000
M25.4 Effusion of joint
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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