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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9924009
log Bayes Factor = 6.18168
Chromosome 16   position 11,782,049  (GRCh37) Explore rs9924009 on Ensembl!
Variant rs9924009 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M15-M19 Arthrosis
0.988 0.012 0.000
Chapter XI Diseases of the digestive system
0.976 0.024 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
Chapter XXI Factors influencing health status and contact with health services
0.972 0.028 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
Chapter IX Diseases of the circulatory system
0.959 0.041 0.000
M54 Dorsalgia
0.947 0.053 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.945 0.055 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.943 0.057 0.000
M70-M79 Other soft tissue disorders
0.933 0.067 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.903 0.097 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.897 0.103 0.000
K50-K52 Noninfective enteritis and colitis
0.893 0.107 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.892 0.108 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.890 0.110 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.890 0.110 0.000
M18 Arthrosis of first carpometacarpal joint
0.890 0.110 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.889 0.111 0.000
Chapter VIII Diseases of the ear and mastoid process
0.889 0.111 0.000
M16 Coxarthrosis [arthrosis of hip]
0.887 0.113 0.000
I60-I69 Cerebrovascular diseases
0.875 0.125 0.000
I10-I15 Hypertensive diseases
0.873 0.127 0.000
M54.9 Dorsalgia, unspecified
0.866 0.134 0.000
Chapter II Neoplasms
0.856 0.144 0.000
M17 Gonarthrosis [arthrosis of knee]
0.854 0.146 0.000
M54.5 Low back pain
0.854 0.146 0.000
M75 Shoulder lesions
0.852 0.148 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.851 0.149 0.000
Chapter VI Diseases of the nervous system
0.851 0.149 0.000
E70-E90 Metabolic disorders
0.850 0.150 0.000
S00-S09 Injuries to the head
0.848 0.152 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.844 0.156 0.000
M19 Other arthrosis
0.843 0.157 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.842 0.158 0.000
K52 Other non-infective gastro-enteritis and colitis
0.841 0.159 0.000
Z60 Problems related to social environment
0.834 0.166 0.000
M05-M14 Inflammatory polyarthropathies
0.827 0.173 0.000
I10 Essential (primary) hypertension
0.822 0.178 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.820 0.180 0.000
M51 Other intervertebral disk disorders
0.811 0.189 0.000
K55-K64 Other diseases of intestines
0.810 0.190 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.808 0.192 0.000
K80 Cholelithiasis
0.806 0.194 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.803 0.197 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.803 0.197 0.000
K70-K77 Diseases of liver
0.800 0.200 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.796 0.204 0.000
Z60.2 Living alone
0.793 0.207 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.791 0.209 0.000
Z43 Attention to artificial openings
0.790 0.210 0.000
I67 Other cerebrovascular diseases
0.790 0.210 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.784 0.216 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.783 0.217 0.000
E00-E07 Disorders of thyroid gland
0.778 0.222 0.000
K35-K38 Diseases of appendix
0.776 0.224 0.000
L60-L75 Disorders of skin appendages
0.774 0.226 0.000
E50-E64 Other nutritional deficiencies
0.770 0.230 0.000
S09 Other and unspecified injuries of head
0.770 0.230 0.000
Z45 Adjustment and management of implanted device
0.770 0.230 0.000
M16.1 Other primary coxarthrosis
0.767 0.233 0.000
S60-S69 Injuries to the wrist and hand
0.765 0.235 0.000
Z51 Other medical care
0.763 0.237 0.000
Chapter V Mental and behavioural disorders
0.763 0.237 0.000
I73 Other peripheral vascular diseases
0.757 0.243 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.755 0.245 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.754 0.246 0.000
Chapter X Diseases of the respiratory system
0.754 0.246 0.000
S80-S89 Injuries to the knee and lower leg
0.752 0.247 0.000
L40-L45 Papulosquamous disorders
0.750 0.250 0.000
E65-E68 Obesity and other hyperalimentation
0.748 0.251 0.000
M54.3 Sciatica
0.748 0.252 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.748 0.252 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.747 0.253 0.000
Chapter I Certain infectious and parasitic diseases
0.747 0.253 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.746 0.254 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.746 0.254 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.745 0.255 0.000
I77 Other disorders of arteries and arterioles
0.740 0.260 0.000
K82 Other diseases of gallbladder
0.739 0.261 0.000
G40-G47 Episodic and paroxysmal disorders
0.738 0.262 0.000
M16.9 Coxarthrosis, unspecified
0.737 0.263 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.734 0.266 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.733 0.267 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.732 0.268 0.000
H90-H95 Other disorders of ear
0.730 0.270 0.000
M13 Other arthritis
0.730 0.270 0.000
M75.5 Bursitis of shoulder
0.729 0.271 0.000
L20-L30 Dermatitis and eczema
0.726 0.274 0.000
K59 Other functional intestinal disorders
0.725 0.275 0.000
E78.0 Pure hypercholesterolaemia
0.722 0.278 0.000
M17.9 Gonarthrosis, unspecified
0.719 0.281 0.000
M54.59 Low back pain (Site unspecified)
0.719 0.281 0.000
Z73 Problems related to life-management difficulty
0.718 0.282 0.000
S70-S79 Injuries to the hip and thigh
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M86-M90 Other osteopathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
C15-C26 Malignant neoplasms of digestive organs
0.716 0.284 0.000
M80-M85 Disorders of bone density and structure
0.715 0.285 0.000
S09.9 Unspecified injury of head
0.714 0.286 0.000
I72 Other aneurysm
0.711 0.289 0.000
E04 Other non-toxic goitre
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
M15 Polyarthrosis
0.708 0.292 0.000
M75.4 Impingement syndrome of shoulder
0.707 0.293 0.000
M19.0 Primary arthrosis of other joints
0.707 0.293 0.000
M54.57 Low back pain (Lumbosacral region)
0.704 0.296 0.000
M75.1 Rotator cuff syndrome
0.704 0.296 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.703 0.297 0.000
M17.1 Other primary gonarthrosis
0.701 0.299 0.000
I05-I09 Chronic rheumatic heart diseases
0.701 0.299 0.000
H80-H83 Diseases of inner ear
0.701 0.299 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.700 0.300 0.000
K08 Other disorders of teeth and supporting structures
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.699 0.300 0.000
M50 Cervical disk disorders
0.699 0.300 0.000
Z43.2 Attention to ileostomy
0.699 0.301 0.000
I67.9 Cerebrovascular disease, unspecified
0.697 0.303 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
T66-T78 Other and unspecified effects of external causes
0.696 0.304 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.304 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.696 0.304 0.000
S20-S29 Injuries to the thorax
0.696 0.304 0.000
S10-S19 Injuries to the neck
0.696 0.304 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.695 0.305 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.695 0.305 0.000
M51.2 Other specified intervertebral disk displacement
0.694 0.306 0.000
I69 Sequelae of cerebrovascular disease
0.693 0.307 0.000
G20-G26 Extrapyramidal and movement disorders
0.693 0.307 0.000
Z48 Other surgical follow-up care
0.691 0.309 0.000
S40-S49 Injuries to the shoulder and upper arm
0.690 0.309 0.000
M65-M68 Disorders of synovium and tendon
0.690 0.310 0.000
H65-H75 Diseases of middle ear and mastoid
0.689 0.311 0.000
E83 Disorders of mineral metabolism
0.688 0.311 0.000
Z46 Fitting and adjustment of other devices
0.688 0.312 0.000
I00-I02 Acute rheumatic fever
0.687 0.313 0.000
R12 Heartburn
0.687 0.313 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.687 0.313 0.000
R14 Flatulence and related conditions
0.685 0.315 0.000
K65-K67 Diseases of peritoneum
0.683 0.317 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.682 0.317 0.000
L50-L54 Urticaria and erythema
0.680 0.320 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.679 0.321 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.679 0.321 0.000
M54.8 Other dorsalgia
0.679 0.321 0.000
M54.6 Pain in thoracic spine
0.679 0.321 0.000
M54.4 Lumbago with sciatica
0.679 0.321 0.000
M54.2 Cervicalgia
0.679 0.321 0.000
M54.1 Radiculopathy
0.679 0.321 0.000
M54.0 Panniculitis affecting regions of neck and back
0.679 0.321 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.678 0.322 0.000
E40-E46 Malnutrition
0.678 0.322 0.000
E20-E35 Disorders of other endocrine glands
0.678 0.322 0.000
K86 Other diseases of pancreas
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.677 0.323 0.000
L82 Seborrhoeic keratosis
0.677 0.323 0.000
E78.5 Hyperlipidaemia, unspecified
0.676 0.324 0.000
L10-L14 Bullous disorders
0.676 0.324 0.000
M20-M25 Other joint disorders
0.676 0.324 0.000
Chapter VII Diseases of the eye and adnexa
0.676 0.324 0.000
B95-B98 Bacterial, viral and other infectious agents
0.676 0.324 0.000
K14 Diseases of tongue
0.675 0.325 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.674 0.326 0.000
K76 Other diseases of liver
0.674 0.326 0.000
O00-O08 Pregnancy with abortive outcome
0.673 0.327 0.000
Z74 Problems related to care-provider dependency
0.671 0.329 0.000
K80.4 Calculus of bile duct with cholecystitis
0.670 0.330 0.000
M77 Other enthesopathies
0.669 0.331 0.000
M76 Enthesopathies of lower limb, excluding foot
0.669 0.331 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.669 0.331 0.000
M71 Other bursopathies
0.669 0.331 0.000
I71 Aortic aneurysm and dissection
0.668 0.332 0.000
C51-C58 Malignant neoplasms of female genital organs
0.668 0.332 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.667 0.333 0.000
M45-M49 Spondylopathies
0.666 0.334 0.000
R40 Somnolence, stupor and coma
0.666 0.334 0.000
Z47 Other orthopaedic follow-up care
0.665 0.335 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.665 0.335 0.000
K59.0 Constipation
0.665 0.335 0.000
O47 False labour
0.662 0.338 0.000
M19.9 Arthrosis, unspecified
0.661 0.339 0.000
M13.9 Arthritis, unspecified
0.661 0.339 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.660 0.339 0.000
M54.56 Low back pain (Lumbar region)
0.660 0.340 0.000
G30-G32 Other degenerative diseases of the nervous system
0.660 0.340 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.655 0.345 0.000
K83 Other diseases of biliary tract
0.653 0.346 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.653 0.347 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.649 0.351 0.000
Z51.2 Other chemotherapy
0.649 0.351 0.000
R07 Pain in throat and chest
0.649 0.351 0.000
Z54 Convalescence
0.648 0.352 0.000
Z52 Donors of organs and tissues
0.648 0.352 0.000
Z49 Care involving dialysis
0.648 0.352 0.000
Z44 Fitting and adjustment of external prosthetic device
0.648 0.352 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.648 0.352 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.647 0.353 0.000
K12 Stomatitis and related lesions
0.647 0.353 0.000
S50-S59 Injuries to the elbow and forearm
0.645 0.355 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.643 0.357 0.000
K85 Acute pancreatitis
0.643 0.357 0.000
C79 Secondary malignant neoplasm of other sites
0.643 0.357 0.000
S00 Superficial injury of head
0.642 0.357 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.641 0.359 0.000
K50 Crohn's disease [regional enteritis]
0.641 0.359 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.640 0.359 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.640 0.360 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.640 0.360 0.000
K60 Fissure and fistula of anal and rectal regions
0.640 0.360 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.639 0.361 0.000
Z65 Problems related to other psychosocial circumstances
0.639 0.361 0.000
Z64 Problems related to certain psychosocial circumstances
0.639 0.361 0.000
Z63 Other problems related to primary support group, including family circumstances
0.639 0.361 0.000
Z62 Other problems related to upbringing
0.639 0.361 0.000
Z61 Problems related to negative life events in childhood
0.639 0.361 0.000
Z59 Problems related to housing and economic circumstances
0.639 0.361 0.000
Z58 Problems related to physical environment
0.639 0.361 0.000
Z57 Occupational exposure to risk-factors
0.639 0.361 0.000
Z56 Problems related to employment and unemployment
0.639 0.361 0.000
Z55 Problems related to education and literacy
0.639 0.361 0.000
Z51.3 Blood transfusion without reported diagnosis
0.639 0.361 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.639 0.361 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.638 0.362 0.000
I78 Diseases of capillaries
0.638 0.362 0.000
I74 Arterial embolism and thrombosis
0.638 0.362 0.000
I70 Atherosclerosis
0.638 0.362 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.638 0.362 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.638 0.362 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.638 0.362 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.638 0.362 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.638 0.362 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.638 0.362 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.638 0.362 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.638 0.362 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.638 0.362 0.000
O85-O92 Complications predominantly related to the puerperium
0.638 0.362 0.000
M16.7 Other secondary coxarthrosis
0.636 0.364 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.636 0.364 0.000
M16.5 Other posttraumatic coxarthrosis
0.636 0.364 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.636 0.364 0.000
M16.3 Other dysplastic coxarthrosis
0.636 0.364 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.636 0.364 0.000
M16.0 Primary coxarthrosis, bilateral
0.636 0.364 0.000
K02 Dental caries
0.636 0.364 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.634 0.366 0.000
K11 Diseases of salivary glands
0.634 0.366 0.000
S61 Open wound of wrist and hand
0.634 0.366 0.000
I67.1 Cerebral aneurysm, nonruptured
0.634 0.366 0.000
K58 Irritable bowel syndrome
0.634 0.366 0.000
E04.2 Non-toxic multinodular goitre
0.633 0.367 0.000
K04 Diseases of pulp and periapical tissues
0.633 0.367 0.000
M79.6 Pain in limb
0.633 0.367 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.633 0.367 0.000
K35 Acute appendicitis
0.632 0.368 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.630 0.370 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.629 0.370 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.629 0.371 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.629 0.371 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.627 0.373 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.627 0.373 0.000
I62 Other nontraumatic intracranial haemorrhage
0.627 0.373 0.000
I61 Intracerebral haemorrhage
0.627 0.373 0.000
I60 Subarachnoid haemorrhage
0.627 0.373 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.627 0.373 0.000
I15 Secondary hypertension
0.626 0.374 0.000
I13 Hypertensive heart and renal disease
0.626 0.374 0.000
I11 Hypertensive heart disease
0.626 0.374 0.000
K82.8 Other specified diseases of gallbladder
0.625 0.375 0.000
M79.7 Fibromyalgia
0.622 0.378 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.622 0.378 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.621 0.379 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.621 0.379 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.621 0.379 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.621 0.379 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.621 0.379 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.621 0.379 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.621 0.379 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.621 0.379 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.621 0.379 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.621 0.379 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.620 0.380 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.620 0.380 0.000
K01 Embedded and impacted teeth
0.619 0.381 0.000
I73.9 Peripheral vascular disease, unspecified
0.617 0.383 0.000
Z51.8 Other specified medical care
0.617 0.383 0.000
M25 Other joint disorders, not elsewhere classified
0.615 0.385 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.615 0.385 0.000
I63 Cerebral infarction
0.614 0.386 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.613 0.386 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.613 0.386 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.613 0.386 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.613 0.386 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.613 0.386 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.613 0.386 0.000
G47 Sleep disorders
0.613 0.387 0.000
Chapter XX External causes of morbidity and mortality
0.613 0.387 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.613 0.387 0.000
M17.5 Other secondary gonarthrosis
0.612 0.388 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.612 0.388 0.000
M17.3 Other posttraumatic gonarthrosis
0.612 0.388 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.612 0.388 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.612 0.388 0.000
M54.55 Low back pain (Thoracolumbar region)
0.612 0.388 0.000
M54.54 Low back pain-Thoracic
0.612 0.388 0.000
M54.53 Low back pain-Cervicothoracic
0.612 0.388 0.000
M54.52 Low back pain-Cervical
0.612 0.388 0.000
M54.51 Low back pain-Occipit-atl-axl
0.612 0.388 0.000
M54.50 Low back pain (Multiple sites in spine)
0.612 0.388 0.000
I73.0 Raynaud's syndrome
0.612 0.388 0.000
O80-O84 Delivery
0.611 0.389 0.000
M75.8 Other shoulder lesions
0.611 0.389 0.000
M75.9 Shoulder lesion, unspecified
0.611 0.389 0.000
M75.3 Calcific tendinitis of shoulder
0.611 0.389 0.000
M75.2 Bicipital tendinitis
0.611 0.389 0.000
K10 Other diseases of jaws
0.610 0.389 0.000
K09 Cysts of oral region, not elsewhere classified
0.610 0.389 0.000
K07 Dentofacial anomalies [including malocclusion]
0.610 0.389 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.610 0.389 0.000
K03 Other diseases of hard tissues of teeth
0.610 0.389 0.000
K00 Disorders of tooth development and eruption
0.610 0.389 0.000
G70-G73 Diseases of myoneural junction and muscle
0.610 0.390 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.610 0.390 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.610 0.390 0.000
E88 Other metabolic disorders
0.609 0.391 0.000
E85 Amyloidosis
0.609 0.391 0.000
E84 Cystic fibrosis
0.609 0.391 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.609 0.391 0.000
E79 Disorders of purine and pyrimidine metabolism
0.609 0.391 0.000
E77 Disorders of glycoprotein metabolism
0.609 0.391 0.000
E76 Disorders of glycosaminoglycan metabolism
0.609 0.391 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.609 0.391 0.000
E74 Other disorders of carbohydrate metabolism
0.609 0.391 0.000
E73 Lactose intolerance
0.609 0.391 0.000
E72 Other disorders of amino-acid metabolism
0.609 0.391 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.609 0.391 0.000
E70 Disorders of aromatic amino-acid metabolism
0.609 0.391 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.609 0.391 0.000
J30-J39 Other diseases of upper respiratory tract
0.609 0.391 0.000
Z41 Procedures for purposes other than remedying health state
0.609 0.391 0.000
S08 Traumatic amputation of part of head
0.608 0.392 0.000
S07 Crushing injury of head
0.608 0.392 0.000
S06 Intracranial injury
0.608 0.392 0.000
S05 Injury of eye and orbit
0.608 0.392 0.000
S04 Injury of cranial nerves
0.608 0.392 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.608 0.392 0.000
S02 Fracture of skull and facial bones
0.608 0.392 0.000
E61 Deficiency of other nutrient elements
0.607 0.393 0.000
E66 Obesity
0.607 0.393 0.000
K51 Ulcerative colitis
0.607 0.393 0.000
Z72 Problems related to lifestyle
0.606 0.394 0.000
M54.39 Sciatica (Site unspecified)
0.606 0.394 0.000
Z76 Persons encountering health services in other circumstances
0.605 0.395 0.000
Z75 Problems related to medical facilities and other health care
0.605 0.395 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.605 0.395 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.605 0.395 0.000
Z40 Prophylactic surgery
0.605 0.395 0.000
L40 Psoriasis
0.605 0.395 0.000
M19.8 Other specified arthrosis
0.604 0.396 0.000
M19.2 Other secondary arthrosis
0.604 0.396 0.000
M19.1 Posttraumatic arthrosis of other joints
0.604 0.396 0.000
O20 Haemorrhage in early pregnancy
0.604 0.396 0.000
R42 Dizziness and giddiness
0.604 0.396 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.604 0.396 0.000
T87 Complications peculiar to reattachment and amputation
0.604 0.396 0.000
T86 Failure and rejection of transplanted organs and tissues
0.604 0.396 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.604 0.396 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.604 0.396 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.603 0.397 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.603 0.397 0.000
K52.3 Indeterminate colitis
0.603 0.397 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.603 0.397 0.000
K52.1 Toxic gastro-enteritis and colitis
0.603 0.397 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.603 0.397 0.000
E53 Deficiency of other B group vitamins
0.603 0.397 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.602 0.397 0.000
K05 Gingivitis and periodontal diseases
0.602 0.398 0.000
R10 Abdominal and pelvic pain
0.602 0.398 0.000
G90-G99 Other disorders of the nervous system
0.602 0.398 0.000
J00-J06 Acute upper respiratory infections
0.601 0.399 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.601 0.399 0.000
H91 Other hearing loss
0.600 0.400 0.000
Z45.2 Adjustment and management of vascular access device
0.599 0.401 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.599 0.401 0.000
Z60.9 Problem related to social environment, unspecified
0.598 0.402 0.000
Z60.8 Other problems related to social environment
0.598 0.402 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.598 0.402 0.000
Z60.4 Social exclusion and rejection
0.598 0.402 0.000
Z60.3 Acculturation difficulty
0.598 0.402 0.000
Z60.1 Atypical parenting situation
0.598 0.402 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.598 0.402 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.598 0.402 0.000
L27 Dermatitis due to substances taken internally
0.597 0.403 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.597 0.403 0.000
S82 Fracture of lower leg, including ankle
0.596 0.404 0.000
C43 Malignant melanoma of skin
0.596 0.404 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.596 0.404 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.596 0.404 0.000
R27 Other lack of coordination
0.596 0.404 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.596 0.404 0.000
C20 Malignant neoplasm of rectum
0.594 0.406 0.000
Z04 Examination and observation for other reasons
0.594 0.406 0.000
K81 Cholecystitis
0.593 0.407 0.000
M14 Arthropathies in other diseases classified elsewhere
0.593 0.407 0.000
M12 Other specific arthropathies
0.593 0.407 0.000
M11 Other crystal arthropathies
0.593 0.407 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.593 0.407 0.000
M08 Juvenile arthritis
0.593 0.407 0.000
M07 Psoriatic and enteropathic arthropathies
0.593 0.407 0.000
M05 Seropositive rheumatoid arthritis
0.593 0.407 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.593 0.407 0.000
Z43.3 Attention to colostomy
0.592 0.408 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.591 0.409 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.590 0.409 0.000
I77.1 Stricture of artery
0.590 0.410 0.000
M79.8 Other specified soft tissue disorders
0.590 0.410 0.000
M70.6 Trochanteric bursitis
0.589 0.411 0.000
O36 Maternal care for other known or suspected foetal problems
0.589 0.411 0.000
M10 Gout
0.587 0.413 0.000
T81 Complications of procedures, not elsewhere classified
0.586 0.414 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.586 0.414 0.000
Z50 Care involving use of rehabilitation procedures
0.585 0.415 0.000
R07.4 Chest pain, unspecified
0.585 0.415 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.584 0.415 0.000
Z98 Other postsurgical states
0.584 0.415 0.000
I67.8 Other specified cerebrovascular diseases
0.584 0.416 0.000
T51 Toxic effect of alcohol
0.583 0.417 0.000
I72.4 Aneurysm of artery of lower extremity
0.583 0.417 0.000
M17.0 Primary gonarthrosis, bilateral
0.583 0.417 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.582 0.418 0.000
M51.3 Other specified intervertebral disk degeneration
0.582 0.418 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.582 0.418 0.000
M51.9 Intervertebral disk disorder, unspecified
0.582 0.418 0.000
M51.8 Other specified intervertebral disk disorders
0.582 0.418 0.000
M51.4 Schmorl's nodes
0.582 0.418 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.582 0.418 0.000
Z48.0 Attention to surgical dressings and sutures
0.581 0.419 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.580 0.419 0.000
K55 Vascular disorders of intestine
0.580 0.419 0.000
G40 Epilepsy
0.580 0.420 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.580 0.420 0.000
G20 Parkinson's disease
0.580 0.420 0.000
I30-I52 Other forms of heart disease
0.579 0.420 0.000
C34 Malignant neoplasm of bronchus and lung
0.579 0.421 0.000
C64-C68 Malignant neoplasms of urinary tract
0.579 0.421 0.000
I69.3 Sequelae of cerebral infarction
0.578 0.422 0.000
K80.3 Calculus of bile duct with cholangitis
0.578 0.422 0.000
K80.8 Other cholelithiasis
0.578 0.422 0.000
I12 Hypertensive renal disease
0.577 0.423 0.000
R46 Symptoms and signs involving appearance and behaviour
0.575 0.424 0.000
R45 Symptoms and signs involving emotional state
0.575 0.424 0.000
R43 Disturbances of smell and taste
0.575 0.424 0.000
Z42 Follow-up care involving plastic surgery
0.574 0.426 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.574 0.426 0.000
K77 Liver disorders in diseases classified elsewhere
0.574 0.426 0.000
K75 Other inflammatory liver diseases
0.574 0.426 0.000
K74 Fibrosis and cirrhosis of liver
0.574 0.426 0.000
K73 Chronic hepatitis, not elsewhere classified
0.574 0.426 0.000
K72 Hepatic failure, not elsewhere classified
0.574 0.426 0.000
K71 Toxic liver disease
0.574 0.426 0.000
K70 Alcoholic liver disease
0.574 0.426 0.000
H80 Otosclerosis
0.571 0.429 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.570 0.429 0.000
E78.8 Other disorders of lipoprotein metabolism
0.570 0.429 0.000
E78.6 Lipoprotein deficiency
0.570 0.429 0.000
E78.4 Other hyperlipidaemia
0.570 0.429 0.000
E78.3 Hyperchylomicronaemia
0.570 0.429 0.000
E78.2 Mixed hyperlipidaemia
0.570 0.429 0.000
E78.1 Pure hyperglyceridaemia
0.570 0.429 0.000
R11 Nausea and vomiting
0.570 0.430 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.570 0.430 0.000
E83.4 Disorders of magnesium metabolism
0.570 0.430 0.000
E04.9 Non-toxic goitre, unspecified
0.570 0.430 0.000
M72 Fibroblastic disorders
0.569 0.431 0.000
J90-J94 Other diseases of pleura
0.569 0.431 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.569 0.431 0.000
R40.2 Coma, unspecified
0.568 0.431 0.000
T31 Burns classified according to extent of body surface involved
0.568 0.432 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.567 0.433 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.567 0.433 0.000
L94 Other localised connective tissue disorders
0.567 0.433 0.000
L93 Lupus erythematosus
0.567 0.433 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.567 0.433 0.000
L89 Decubitus ulcer
0.567 0.433 0.000
L87 Transepidermal elimination disorders
0.567 0.433 0.000
L85 Other epidermal thickening
0.567 0.433 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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