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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74934799
log Bayes Factor = 13.1374
Chromosome 16   position 75,468,490  (GRCh37) Explore rs74934799 on Ensembl!
Variant rs74934799 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
M54 Dorsalgia
0.991 0.009 0.000
M79.6 Pain in limb
0.986 0.014 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
A00-A09 Intestinal infectious diseases
0.983 0.017 0.000
M23 Internal derangement of knee
0.983 0.017 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.980 0.020 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.977 0.023 0.000
G90-G99 Other disorders of the nervous system
0.973 0.027 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.972 0.028 0.000
M54.5 Low back pain
0.971 0.029 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.959 0.041 0.000
M40-M43 Deforming dorsopathies
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.949 0.051 0.000
Chapter VIII Diseases of the ear and mastoid process
0.946 0.054 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.942 0.058 0.000
M45-M49 Spondylopathies
0.926 0.074 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.919 0.081 0.000
M75 Shoulder lesions
0.918 0.082 0.000
M54.56 Low back pain (Lumbar region)
0.918 0.082 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.917 0.083 0.000
G93 Other disorders of brain
0.915 0.085 0.000
M79.66 Pain in limb (Lower leg)
0.914 0.086 0.000
M65-M68 Disorders of synovium and tendon
0.911 0.089 0.000
G30-G32 Other degenerative diseases of the nervous system
0.910 0.089 0.000
H60-H62 Diseases of external ear
0.908 0.092 0.000
M41 Scoliosis
0.908 0.092 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.906 0.094 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.904 0.096 0.000
Y40 Systemic antibiotics
0.904 0.096 0.000
T81 Complications of procedures, not elsewhere classified
0.903 0.097 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.902 0.098 0.000
M79.2 Neuralgia and neuritis, unspecified
0.901 0.099 0.000
M25.5 Pain in joint
0.900 0.100 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.899 0.101 0.000
M54.9 Dorsalgia, unspecified
0.895 0.105 0.000
M79.60 Pain in limb (Multiple sites)
0.891 0.109 0.000
M79.69 Pain in limb (Site unspecified)
0.888 0.112 0.000
Chapter XI Diseases of the digestive system
0.880 0.120 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.877 0.123 0.000
M41.9 Scoliosis, unspecified
0.876 0.124 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.875 0.125 0.000
M79.7 Fibromyalgia
0.874 0.126 0.000
M48 Other spondylopathies
0.871 0.129 0.000
H61 Other disorders of external ear
0.868 0.132 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.868 0.132 0.000
M05-M14 Inflammatory polyarthropathies
0.868 0.132 0.000
S70-S79 Injuries to the hip and thigh
0.866 0.134 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.865 0.135 0.000
B35-B49 Mycoses
0.863 0.137 0.000
M50 Cervical disk disorders
0.863 0.137 0.000
K50-K52 Noninfective enteritis and colitis
0.861 0.139 0.000
M54.3 Sciatica
0.860 0.140 0.000
M67 Other disorders of synovium and tendon
0.860 0.140 0.000
G30 Alzheimer's disease
0.859 0.141 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.857 0.143 0.000
G96 Other disorders of central nervous system
0.852 0.148 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.852 0.148 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.851 0.149 0.000
G40-G47 Episodic and paroxysmal disorders
0.848 0.152 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.843 0.157 0.000
M54.59 Low back pain (Site unspecified)
0.843 0.157 0.000
O16 Unspecified maternal hypertension
0.842 0.158 0.000
T93 Sequelae of injuries of lower limb
0.841 0.159 0.000
M75.5 Bursitis of shoulder
0.835 0.165 0.000
Y43 Primarily systemic agents
0.835 0.165 0.000
M80-M85 Disorders of bone density and structure
0.834 0.166 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.829 0.171 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.828 0.172 0.000
M22 Disorders of patella
0.828 0.172 0.000
H65-H75 Diseases of middle ear and mastoid
0.823 0.177 0.000
M48.0 Spinal stenosis
0.823 0.177 0.000
G30.9 Alzheimer's disease, unspecified
0.822 0.178 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.822 0.178 0.000
M75.1 Rotator cuff syndrome
0.822 0.178 0.000
M24 Other specific joint derangements
0.818 0.182 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.817 0.183 0.000
Y57 Other and unspecified drugs and medicaments
0.817 0.183 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.817 0.183 0.000
K50 Crohn's disease [regional enteritis]
0.815 0.185 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.814 0.186 0.000
G91 Hydrocephalus
0.810 0.190 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.809 0.191 0.000
M54.50 Low back pain (Multiple sites in spine)
0.808 0.191 0.000
Chapter XIV Diseases of the genitourinary system
0.806 0.194 0.000
M77 Other enthesopathies
0.805 0.195 0.000
Y52 Agents primarily affecting the cardiovascular system
0.804 0.196 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.803 0.197 0.000
K65-K67 Diseases of peritoneum
0.802 0.198 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.801 0.199 0.000
M79.1 Myalgia
0.798 0.201 0.000
M67.8 Other specified disorders of synovium and tendon
0.796 0.204 0.000
G56 Mononeuropathies of upper limb
0.796 0.204 0.000
V40-V49 Car occupant injured in transport accident
0.794 0.206 0.000
Chapter II Neoplasms
0.794 0.206 0.000
M25.4 Effusion of joint
0.793 0.207 0.000
B15-B19 Viral hepatitis
0.793 0.207 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.791 0.209 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.789 0.211 0.000
K51 Ulcerative colitis
0.788 0.212 0.000
G93.3 Postviral fatigue syndrome
0.787 0.213 0.000
M20 Acquired deformities of fingers and toes
0.786 0.214 0.000
G20-G26 Extrapyramidal and movement disorders
0.785 0.215 0.000
M79.79 Fibromyalgia (Site unspecified)
0.785 0.215 0.000
A04 Other bacterial intestinal infections
0.783 0.217 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.782 0.218 0.000
M54.2 Cervicalgia
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.773 0.227 0.000
G93.2 Benign intracranial hypertension
0.771 0.229 0.000
Y95 Nosocomial condition
0.770 0.230 0.000
Y40.0 Penicillins
0.769 0.231 0.000
M25.53 Pain in joint (Forearm)
0.767 0.233 0.000
Y40.8 Other systemic antibiotics
0.767 0.233 0.000
Chapter V Mental and behavioural disorders
0.767 0.233 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.766 0.234 0.000
G96.0 Cerebrospinal fluid leak
0.766 0.234 0.000
M35 Other systemic involvement of connective tissue
0.765 0.235 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.764 0.236 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.764 0.236 0.000
M91-M94 Chondropathies
0.763 0.237 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.763 0.237 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.762 0.238 0.000
G54 Nerve root and plexus disorders
0.758 0.242 0.000
O00-O08 Pregnancy with abortive outcome
0.757 0.243 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.755 0.245 0.000
M07 Psoriatic and enteropathic arthropathies
0.752 0.248 0.000
M48.02 Spinal stenosis (Cervical region)
0.752 0.248 0.000
M34 Systemic sclerosis
0.752 0.248 0.000
M21 Other acquired deformities of limbs
0.751 0.248 0.000
M54.36 Sciatica (Lumbar region)
0.750 0.250 0.000
M43 Other deforming dorsopathies
0.750 0.250 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.749 0.251 0.000
M50.2 Other cervical disk displacement
0.749 0.251 0.000
M45 Ankylosing spondylitis
0.748 0.251 0.000
M54.6 Pain in thoracic spine
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
M15-M19 Arthrosis
0.748 0.252 0.000
B35 Dermatophytosis
0.746 0.254 0.000
M46 Other inflammatory spondylopathies
0.745 0.255 0.000
X20-X29 Contact with venomous animals and plants
0.745 0.255 0.000
G47 Sleep disorders
0.744 0.256 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.744 0.256 0.000
M79.8 Other specified soft tissue disorders
0.743 0.257 0.000
G40 Epilepsy
0.743 0.257 0.000
T90 Sequelae of injuries of head
0.741 0.259 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.741 0.259 0.000
T81.9 Unspecified complication of procedure
0.741 0.259 0.000
M25.8 Other specified joint disorders
0.741 0.259 0.000
S40-S49 Injuries to the shoulder and upper arm
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
A02 Other Salmonella infections
0.734 0.266 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.733 0.267 0.000
K65 Peritonitis
0.732 0.268 0.000
N00-N08 Glomerular diseases
0.732 0.268 0.000
M79.5 Residual foreign body in soft tissue
0.732 0.268 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.731 0.269 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.731 0.269 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.730 0.270 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.730 0.270 0.000
N10-N16 Renal tubulo-interstitial diseases
0.730 0.270 0.000
H60 Otitis externa
0.729 0.271 0.000
H61.2 Impacted cerumen
0.728 0.272 0.000
S72 Fracture of femur
0.727 0.273 0.000
Y43.3 Other antineoplastic drugs
0.726 0.274 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.726 0.274 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
G90 Disorders of autonomic nervous system
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.723 0.277 0.000
N99-N99 Other disorders of the genitourinary system
0.722 0.277 0.000
M16 Coxarthrosis [arthrosis of hip]
0.722 0.278 0.000
M25.59 Pain in joint (Site unspecified)
0.722 0.278 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.721 0.278 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.721 0.279 0.000
H61.8 Other specified disorders of external ear
0.720 0.280 0.000
M71 Other bursopathies
0.719 0.281 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.719 0.281 0.000
Chapter IX Diseases of the circulatory system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G62 Other polyneuropathies
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
M79.9 Soft tissue disorder, unspecified
0.715 0.285 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.715 0.285 0.000
M79.3 Panniculitis, unspecified
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Y45.0 Opioids and related analgesics
0.714 0.286 0.000
H61.0 Perichondritis of external ear
0.713 0.287 0.000
M53 Other dorsopathies, not elsewhere classified
0.713 0.287 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.712 0.288 0.000
G93.9 Disorder of brain, unspecified
0.712 0.288 0.000
G51 Facial nerve disorders
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.711 0.288 0.000
G93.8 Other specified disorders of brain
0.711 0.289 0.000
K50.1 Crohn's disease of large intestine
0.711 0.289 0.000
M54.8 Other dorsalgia
0.710 0.289 0.000
M54.0 Panniculitis affecting regions of neck and back
0.710 0.289 0.000
H61.9 Disorder of external ear, unspecified
0.710 0.290 0.000
T92 Sequelae of injuries of upper limb
0.710 0.290 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.709 0.291 0.000
M20.4 Other hammer toe(s) (acquired)
0.708 0.292 0.000
M16.9 Coxarthrosis, unspecified
0.708 0.292 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.708 0.292 0.000
G56.2 Lesion of ulnar nerve
0.708 0.292 0.000
M79.68 Pain in limb (Other)
0.707 0.293 0.000
M79.64 Pain in limb (Hand)
0.707 0.293 0.000
M79.61 Pain in limb (Shoulder region)
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
S79 Other and unspecified injuries of hip and thigh
0.706 0.293 0.000
M79.0 Rheumatism, unspecified
0.706 0.293 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.706 0.294 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.706 0.294 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.706 0.294 0.000
A07 Other protozoal intestinal diseases
0.705 0.295 0.000
A06 Amoebiasis
0.705 0.295 0.000
A05 Other bacterial foodborne intoxications
0.705 0.295 0.000
A03 Shigellosis
0.705 0.295 0.000
A01 Typhoid and paratyphoid fevers
0.705 0.295 0.000
A00 Cholera
0.705 0.295 0.000
M23.4 Loose body in knee
0.705 0.295 0.000
M23.9 Internal derangement of knee, unspecified
0.705 0.295 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.705 0.295 0.000
M23.5 Chronic instability of knee
0.705 0.295 0.000
M23.1 Discoid meniscus (congenital)
0.705 0.295 0.000
M23.0 Cystic meniscus
0.705 0.295 0.000
Y45.2 Propionic acid derivatives
0.704 0.295 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.705 0.295 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.704 0.296 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
M54.57 Low back pain (Lumbosacral region)
0.703 0.297 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.702 0.297 0.000
M79.67 Pain in limb (Ankle and foot)
0.702 0.298 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.701 0.299 0.000
K10 Other diseases of jaws
0.701 0.299 0.000
N25-N29 Other disorders of kidney and ureter
0.700 0.300 0.000
W20-W49 Exposure to inanimate mechanical forces
0.699 0.301 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.699 0.301 0.000
M06 Other rheumatoid arthritis
0.699 0.301 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.698 0.302 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.698 0.302 0.000
G92 Toxic encephalopathy
0.698 0.302 0.000
Chapter XXII Codes for special purposes
0.697 0.303 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.696 0.303 0.000
M54.55 Low back pain (Thoracolumbar region)
0.696 0.304 0.000
M54.54 Low back pain-Thoracic
0.696 0.304 0.000
M54.53 Low back pain-Cervicothoracic
0.696 0.304 0.000
M54.52 Low back pain-Cervical
0.696 0.304 0.000
M54.51 Low back pain-Occipit-atl-axl
0.696 0.304 0.000
Y40.9 Systemic antibiotic, unspecified
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.695 0.305 0.000
K51.8 Other ulcerative colitis
0.695 0.305 0.000
N40-N51 Diseases of male genital organs
0.695 0.305 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.693 0.307 0.000
G95 Other diseases of spinal cord
0.692 0.308 0.000
H71 Cholesteatoma of middle ear
0.691 0.309 0.000
K35-K38 Diseases of appendix
0.690 0.310 0.000
M35.0 Sicca syndrome [Sjogren]
0.690 0.310 0.000
M22.2 Patellofemoral disorders
0.689 0.311 0.000
S20-S29 Injuries to the thorax
0.688 0.311 0.000
T33-T35 Frostbite
0.687 0.313 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.687 0.313 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.687 0.313 0.000
T00-T07 Injuries involving multiple body regions
0.687 0.313 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.686 0.314 0.000
S70 Superficial injury of hip and thigh
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
T79-T79 Certain early complications of trauma
0.685 0.315 0.000
M42 Spinal osteochondrosis
0.683 0.317 0.000
M40 Kyphosis and lordosis
0.683 0.317 0.000
M82 Osteoporosis in diseases classified elsewhere
0.683 0.317 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.682 0.318 0.000
N43 Hydrocele and spermatocele
0.682 0.318 0.000
K51.2 Ulcerative (chronic) proctitis
0.682 0.318 0.000
D00-D09 In situ neoplasms
0.681 0.319 0.000
H65 Nonsuppurative otitis media
0.681 0.319 0.000
K50.0 Crohn's disease of small intestine
0.681 0.319 0.000
M25.9 Joint disorder, unspecified
0.681 0.319 0.000
M25.3 Other instability of joint
0.681 0.319 0.000
M25.2 Flail joint
0.681 0.319 0.000
M25.1 Fistula of joint
0.681 0.319 0.000
M25.0 Haemarthrosis
0.681 0.319 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.680 0.320 0.000
X45 Accidental poisoning by and exposure to alcohol
0.679 0.320 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.679 0.321 0.000
M24.1 Other articular cartilage disorders
0.679 0.321 0.000
M54.4 Lumbago with sciatica
0.678 0.321 0.000
M25.50 Pain in joint (Multiple sites)
0.677 0.322 0.000
A30-A49 Other bacterial diseases
0.676 0.324 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.676 0.324 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.676 0.324 0.000
Y60.0 During surgical operation
0.675 0.325 0.000
T87 Complications peculiar to reattachment and amputation
0.675 0.325 0.000
T86 Failure and rejection of transplanted organs and tissues
0.675 0.325 0.000
G47.3 Sleep apnoea
0.675 0.325 0.000
N13 Obstructive and reflux uropathy
0.674 0.326 0.000
M50.3 Other cervical disk degeneration
0.674 0.326 0.000
N43.3 Hydrocele, unspecified
0.674 0.326 0.000
M10 Gout
0.673 0.327 0.000
K11 Diseases of salivary glands
0.672 0.328 0.000
M75.3 Calcific tendinitis of shoulder
0.672 0.328 0.000
T66-T78 Other and unspecified effects of external causes
0.671 0.329 0.000
M75.4 Impingement syndrome of shoulder
0.670 0.330 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.670 0.330 0.000
B37 Candidiasis
0.670 0.330 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.670 0.330 0.000
K90-K93 Other diseases of the digestive system
0.670 0.330 0.000
M07.3 Other psoriatic arthropathies
0.669 0.331 0.000
G70-G73 Diseases of myoneural junction and muscle
0.669 0.331 0.000
K70-K77 Diseases of liver
0.669 0.331 0.000
G93.0 Cerebral cysts
0.669 0.331 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.669 0.331 0.000
G91.1 Obstructive hydrocephalus
0.668 0.332 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.666 0.333 0.000
H61.3 Acquired stenosis of external ear canal
0.666 0.333 0.000
O02 Other abnormal products of conception
0.665 0.335 0.000
M49 Spondylopathies in diseases classified elsewhere
0.664 0.336 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.664 0.336 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.663 0.337 0.000
M22.8 Other disorders of patella
0.663 0.337 0.000
M11 Other crystal arthropathies
0.662 0.338 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.662 0.338 0.000
M75.9 Shoulder lesion, unspecified
0.662 0.338 0.000
Y57.9 Drug or medicament, unspecified
0.662 0.338 0.000
K50.8 Other Crohn's disease
0.661 0.339 0.000
G93.4 Encephalopathy, unspecified
0.661 0.339 0.000
K12 Stomatitis and related lesions
0.660 0.340 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.659 0.341 0.000
M75.8 Other shoulder lesions
0.658 0.341 0.000
M75.2 Bicipital tendinitis
0.658 0.341 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.658 0.342 0.000
T98 Sequelae of other and unspecified effects of external causes
0.658 0.342 0.000
T95 Sequelae of burns, corrosions and frostbite
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.658 0.342 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.658 0.342 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.658 0.342 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.658 0.342 0.000
G60 Hereditary and idiopathic neuropathy
0.657 0.343 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.656 0.343 0.000
G93.7 Reye's syndrome
0.656 0.344 0.000
G93.6 Cerebral oedema
0.656 0.344 0.000
G93.5 Compression of brain
0.656 0.344 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.656 0.344 0.000
O00 Ectopic pregnancy
0.656 0.344 0.000
M50.1 Cervical disk disorder with radiculopathy
0.656 0.344 0.000
G54.0 Brachial plexus disorders
0.656 0.344 0.000
G50 Disorders of trigeminal nerve
0.655 0.345 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.655 0.345 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.653 0.347 0.000
M66 Spontaneous rupture of synovium and tendon
0.653 0.347 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.653 0.347 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.651 0.349 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.651 0.349 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.651 0.349 0.000
M41.8 Other forms of scoliosis
0.651 0.349 0.000
M41.5 Other secondary scoliosis
0.651 0.349 0.000
M41.4 Neuromuscular scoliosis
0.651 0.349 0.000
M41.3 Thoracogenic scoliosis
0.651 0.349 0.000
M41.2 Other idiopathic scoliosis
0.651 0.349 0.000
M41.1 Juvenile idiopathic scoliosis
0.651 0.349 0.000
M41.0 Infantile idiopathic scoliosis
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
L50-L54 Urticaria and erythema
0.650 0.350 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.650 0.350 0.000
Y44 Agents primarily affecting blood constituents
0.649 0.351 0.000
B18 Chronic viral hepatitis
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.648 0.351 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.648 0.352 0.000
G56.8 Other mononeuropathies of upper limb
0.648 0.352 0.000
Y40.7 Antifungal antibiotics, systemically used
0.648 0.352 0.000
Y40.6 Rifamycins
0.648 0.352 0.000
Y40.5 Aminoglycosides
0.648 0.352 0.000
Y40.4 Tetracyclines
0.648 0.352 0.000
Y40.3 Macrolides
0.648 0.352 0.000
Y40.2 Chloramphenicol group
0.648 0.352 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.648 0.352 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.648 0.352 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.648 0.352 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.648 0.352 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.647 0.353 0.000
M79.62 Pain in limb (Upper arm)
0.647 0.353 0.000
K65.9 Peritonitis, unspecified
0.647 0.353 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.647 0.353 0.000
G52 Disorders of other cranial nerves
0.647 0.353 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.646 0.354 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.646 0.354 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.646 0.354 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.646 0.354 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.646 0.354 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.646 0.354 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.646 0.354 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.646 0.354 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.646 0.354 0.000
M25.58 Pain in joint (Other)
0.645 0.355 0.000
M25.52 Pain in joint (Upper arm)
0.645 0.355 0.000
O85-O92 Complications predominantly related to the puerperium
0.645 0.355 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.642 0.358 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.641 0.358 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.641 0.358 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.641 0.358 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.641 0.358 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.641 0.358 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.641 0.358 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.641 0.358 0.000
M48.09 Spinal stenosis (Site unspecified)
0.640 0.359 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.640 0.360 0.000
M86-M90 Other osteopathies
0.639 0.360 0.000
G25 Other extrapyramidal and movement disorders
0.639 0.360 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.639 0.361 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.639 0.361 0.000
M54.1 Radiculopathy
0.639 0.361 0.000
Chapter VII Diseases of the eye and adnexa
0.639 0.361 0.000
N03 Chronic nephritic syndrome
0.639 0.361 0.000
Y57.5 X-ray contrast media
0.637 0.363 0.000
M25.54 Pain in joint (Hand)
0.636 0.364 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.636 0.364 0.000
M54.39 Sciatica (Site unspecified)
0.636 0.364 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.635 0.364 0.000
H70 Mastoiditis and related conditions
0.635 0.364 0.000
M72 Fibroblastic disorders
0.635 0.365 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.635 0.365 0.000
K14 Diseases of tongue
0.634 0.366 0.000
K51.4 Pseudopolyposis of colon
0.633 0.367 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.633 0.367 0.000
M54.37 Sciatica (Lumbosacral region)
0.633 0.367 0.000
M79.63 Pain in limb (Forearm)
0.632 0.367 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.632 0.368 0.000
K50.9 Crohn's disease, unspecified
0.632 0.368 0.000
G35 Multiple sclerosis
0.631 0.368 0.000
A04.8 Other specified bacterial intestinal infections
0.631 0.369 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.630 0.370 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.629 0.370 0.000
W00-W19 Falls
0.629 0.371 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.629 0.371 0.000
Y45.8 Other analgesics and antipyretics
0.629 0.371 0.000
Y45.5 4-Aminophenol derivatives
0.629 0.371 0.000
Y45.4 Antirheumatics
0.629 0.371 0.000
Y45.1 Salicylates
0.629 0.371 0.000
M54.22 Cervicalgia (Cervical region)
0.629 0.371 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.628 0.372 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.628 0.372 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.628 0.372 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.628 0.372 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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