TreeWAS – Variant ID: rs12691052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	0.994	0.006
Chapter IX Diseases of the circulatory system	0.990	0.010
Chapter IV Endocrine, nutritional and metabolic diseases	0.988	0.012
I20-I25 Ischaemic heart diseases	0.968	0.032
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.961	0.039
Chapter XIV Diseases of the genitourinary system	0.959	0.041
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.941	0.059
I25 Chronic ischaemic heart disease	0.928	0.072
E70-E90 Metabolic disorders	0.928	0.072
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.904	0.096
Z95 Presence of cardiac and vascular implants and grafts	0.902	0.098
E65-E68 Obesity and other hyperalimentation	0.895	0.105
Chapter II Neoplasms	0.894	0.106
Z00-Z13 Persons encountering health services for examination and investigation	0.888	0.112
Z40-Z54 Persons encountering health services for specific procedures and health care	0.885	0.115
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.877	0.123
R50-R69 General symptoms and signs	0.873	0.127
I30-I52 Other forms of heart disease	0.863	0.137
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.829	0.170
E66 Obesity	0.828	0.172
N30-N39 Other diseases of urinary system	0.826	0.174
E87 Other disorders of fluid, electrolyte and acid-base balance	0.824	0.176
I70-I79 Diseases of arteries, arterioles and capillaries	0.823	0.177
N40-N51 Diseases of male genital organs	0.818	0.182
I25.2 Old myocardial infarction	0.810	0.190
E10-E14 Diabetes mellitus	0.810	0.190
Chapter XV Pregnancy, childbirth and the puerperium	0.803	0.197
I21 Acute myocardial infarction	0.800	0.200
Chapter XX External causes of morbidity and mortality	0.797	0.202
E00-E07 Disorders of thyroid gland	0.790	0.210
Z95.5 Presence of coronary angioplasty implant and graft	0.789	0.211
I20 Angina pectoris	0.785	0.215
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.782	0.218
Chapter XII Diseases of the skin and subcutaneous tissue	0.782	0.218
E66.9 Obesity, unspecified	0.781	0.219
R53 Malaise and fatigue	0.779	0.221
I25.1 Atherosclerotic heart disease	0.779	0.221
N80-N98 Noninflammatory disorders of female genital tract	0.776	0.223
Chapter V Mental and behavioural disorders	0.776	0.224
Z70-Z76 Persons encountering health services in other circumstances	0.775	0.225
Chapter I Certain infectious and parasitic diseases	0.774	0.226
Chapter VI Diseases of the nervous system	0.774	0.226
Z93 Artificial opening status	0.772	0.228
Z85 Personal history of malignant neoplasm	0.771	0.229
Z90 Acquired absence of organs, not elsewhere classified	0.771	0.229
I50 Heart failure	0.769	0.231
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.767	0.233
T81 Complications of procedures, not elsewhere classified	0.766	0.234
R69 Unknown and unspecified causes of morbidity	0.763	0.237
Z45 Adjustment and management of implanted device	0.762	0.237
C15-C26 Malignant neoplasms of digestive organs	0.762	0.238
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.759	0.241
I25.8 Other forms of chronic ischaemic heart disease	0.759	0.241
I25.9 Chronic ischaemic heart disease, unspecified	0.757	0.243
I60-I69 Cerebrovascular diseases	0.755	0.245
Z51 Other medical care	0.750	0.250
R30-R39 Symptoms and signs involving the urinary system	0.747	0.253
N17-N19 Renal failure	0.747	0.253
Z95.1 Presence of aortocoronary bypass graft	0.746	0.254
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.738	0.262
E86 Volume depletion	0.735	0.265
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.733	0.267
N10-N16 Renal tubulo-interstitial diseases	0.732	0.268
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.727	0.273
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.727	0.273
Z96 Presence of other functional implants	0.726	0.274
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.722	0.278
N60-N64 Disorders of breast	0.720	0.280
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M15-M19 Arthrosis	0.716	0.284
N39 Other disorders of urinary system	0.715	0.285
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.713	0.287
E78.0 Pure hypercholesterolaemia	0.712	0.288
I05-I09 Chronic rheumatic heart diseases	0.710	0.290
I00-I02 Acute rheumatic fever	0.710	0.290
E50-E64 Other nutritional deficiencies	0.708	0.292
E40-E46 Malnutrition	0.708	0.292
E20-E35 Disorders of other endocrine glands	0.708	0.292
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.708	0.292
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.707	0.293
T81.4 Infection following a procedure, not elsewhere classified	0.706	0.294
Chapter VIII Diseases of the ear and mastoid process	0.706	0.294
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.705	0.295
Z95.8 Presence of other cardiac and vascular implants and grafts	0.704	0.296
D10-D36 Benign neoplasms	0.704	0.296
Z95.0 Presence of cardiac pacemaker	0.703	0.297
Z87 Personal history of other diseases and conditions	0.703	0.297
I10-I15 Hypertensive diseases	0.702	0.298
C64-C68 Malignant neoplasms of urinary tract	0.701	0.299
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.698	0.302
I95-I99 Other and unspecified disorders of the circulatory system	0.697	0.302
Z80 Family history of malignant neoplasm	0.697	0.303
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.697	0.303
Z03 Medical observation and evaluation for suspected diseases and conditions	0.695	0.304
Z42 Follow-up care involving plastic surgery	0.695	0.305
I24 Other acute ischaemic heart diseases	0.694	0.306
I23 Certain current complications following acute myocardial infarction	0.694	0.306
I22 Subsequent myocardial infarction	0.694	0.306
Z08 Follow-up examination after treatment for malignant neoplasm	0.690	0.310
Chapter VII Diseases of the eye and adnexa	0.689	0.310
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.689	0.311
Z98 Other postsurgical states	0.689	0.311
Z97 Presence of other devices	0.689	0.311
Z94 Transplanted organ and tissue status	0.689	0.311
Z89 Acquired absence of limb	0.689	0.311
Z84 Family history of other conditions	0.689	0.311
Z83 Family history of other specific disorders	0.689	0.311
Z81 Family history of mental and behavioural disorders	0.689	0.311
N99-N99 Other disorders of the genitourinary system	0.688	0.312
N25-N29 Other disorders of kidney and ureter	0.688	0.312
N20-N23 Urolithiasis	0.688	0.312
N00-N08 Glomerular diseases	0.688	0.312
Chapter X Diseases of the respiratory system	0.686	0.314
E87.2 Acidosis	0.683	0.317
M80-M85 Disorders of bone density and structure	0.679	0.321
M50-M54 Other dorsopathies	0.677	0.323
N40 Hyperplasia of prostate	0.677	0.323
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.676	0.324
Z45.2 Adjustment and management of vascular access device	0.675	0.325
R95-R99 Ill-defined and unknown causes of mortality	0.674	0.325
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.674	0.325
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.674	0.325
R47-R49 Symptoms and signs involving speech and voice	0.674	0.325
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.674	0.325
I77 Other disorders of arteries and arterioles	0.674	0.326
M45-M49 Spondylopathies	0.673	0.327
M20-M25 Other joint disorders	0.673	0.327
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.672	0.328
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.669	0.330
I21.9 Acute myocardial infarction, unspecified	0.669	0.331
S00-S09 Injuries to the head	0.666	0.334
I25.6 Silent myocardial ischaemia	0.666	0.334
I25.5 Ischaemic cardiomyopathy	0.666	0.334
I25.4 Coronary artery aneurysm	0.666	0.334
I25.3 Aneurysm of heart	0.666	0.334
I25.0 Atherosclerotic cardiovascular disease, so described	0.666	0.334
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.665	0.334
E88 Other metabolic disorders	0.665	0.334
E85 Amyloidosis	0.665	0.334
E84 Cystic fibrosis	0.665	0.334
E83 Disorders of mineral metabolism	0.665	0.334
E80 Disorders of porphyrin and bilirubin metabolism	0.665	0.334
E79 Disorders of purine and pyrimidine metabolism	0.665	0.334
E77 Disorders of glycoprotein metabolism	0.665	0.334
E76 Disorders of glycosaminoglycan metabolism	0.665	0.334
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.665	0.334
E74 Other disorders of carbohydrate metabolism	0.665	0.334
E73 Lactose intolerance	0.665	0.334
E72 Other disorders of amino-acid metabolism	0.665	0.334
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.665	0.334
E70 Disorders of aromatic amino-acid metabolism	0.665	0.334
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.665	0.334
E87.6 Hypokalaemia	0.664	0.336
N70-N77 Inflammatory diseases of female pelvic organs	0.663	0.337
N39.0 Urinary tract infection, site not specified	0.662	0.338
N43 Hydrocele and spermatocele	0.654	0.346
Z46 Fitting and adjustment of other devices	0.652	0.348
Z91 Personal history of risk-factors, not elsewhere classified	0.650	0.350
E03 Other hypothyroidism	0.649	0.351
Z47 Other orthopaedic follow-up care	0.648	0.352
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.648	0.352
T79-T79 Certain early complications of trauma	0.648	0.352
T66-T78 Other and unspecified effects of external causes	0.648	0.352
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.648	0.352
T36-T50 Poisoning by drugs, medicaments and biological substances	0.648	0.352
T33-T35 Frostbite	0.648	0.352
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.648	0.352
T26-T28 Burns and corrosions confined to eye and internal organs	0.648	0.352
T20-T25 Burns and corrosions of external body surface, specified by site	0.648	0.352
T15-T19 Effects of foreign body entering through natural orifice	0.648	0.352
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.648	0.352
T00-T07 Injuries involving multiple body regions	0.648	0.352
S90-S99 Injuries to the ankle and foot	0.648	0.352
S80-S89 Injuries to the knee and lower leg	0.648	0.352
S70-S79 Injuries to the hip and thigh	0.648	0.352
S60-S69 Injuries to the wrist and hand	0.648	0.352
S50-S59 Injuries to the elbow and forearm	0.648	0.352
S40-S49 Injuries to the shoulder and upper arm	0.648	0.352
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.648	0.352
S20-S29 Injuries to the thorax	0.648	0.352
S10-S19 Injuries to the neck	0.648	0.352
I50.0 Congestive heart failure	0.648	0.352
R33 Retention of urine	0.647	0.353
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.647	0.353
Z95.4 Presence of other heart-valve replacement	0.647	0.353
Z95.3 Presence of xenogenic heart valve	0.647	0.353
Z95.2 Presence of prosthetic heart valve	0.647	0.353
I20.0 Unstable angina	0.645	0.355
M05-M14 Inflammatory polyarthropathies	0.645	0.355
B95-B98 Bacterial, viral and other infectious agents	0.644	0.355
E87.1 Hypo-osmolality and hyponatraemia	0.643	0.357
E67 Other hyperalimentation	0.642	0.358
E68 Sequelae of hyperalimentation	0.642	0.358
E65 Localised adiposity	0.642	0.358
D37-D48 Neoplasms of uncertain or unknown behaviour	0.641	0.359
D00-D09 In situ neoplasms	0.641	0.359
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.641	0.359
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.641	0.359
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.641	0.359
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.641	0.359
C51-C58 Malignant neoplasms of female genital organs	0.641	0.359
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.641	0.359
C40-C41 Malignant neoplasms of bone and articular cartilage	0.641	0.359
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.641	0.359
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.641	0.359
E11 Non-insulin-dependent diabetes mellitus	0.640	0.360
E10 Insulin-dependent diabetes mellitus	0.638	0.362
O60-O75 Complications of labour and delivery	0.638	0.362
R50 Fever of unknown origin	0.637	0.363
Z11 Special screening examination for infectious and parasitic diseases	0.637	0.363
Z10 Routine general health check-up of defined subpopulation	0.637	0.363
Z04 Examination and observation for other reasons	0.637	0.363
Z02 Examination and encounter for administrative purposes	0.637	0.363
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.637	0.363
Z93.2 Ileostomy status	0.637	0.363
I73 Other peripheral vascular diseases	0.636	0.364
I47 Paroxysmal tachycardia	0.635	0.365
Z54 Convalescence	0.635	0.365
Z52 Donors of organs and tissues	0.635	0.365
Z49 Care involving dialysis	0.635	0.365
Z48 Other surgical follow-up care	0.635	0.365
Z44 Fitting and adjustment of external prosthetic device	0.635	0.365
Z43 Attention to artificial openings	0.635	0.365
Z41 Procedures for purposes other than remedying health state	0.635	0.365
Z40 Prophylactic surgery	0.635	0.365
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.634	0.366
N30 Cystitis	0.633	0.366
C50-C50 Malignant neoplasm of breast	0.633	0.367
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.632	0.368
Z50 Care involving use of rehabilitation procedures	0.632	0.368
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.632	0.368
C20 Malignant neoplasm of rectum	0.631	0.369
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.629	0.371
M91-M94 Chondropathies	0.629	0.371
M86-M90 Other osteopathies	0.629	0.371
M65-M68 Disorders of synovium and tendon	0.629	0.371
M60-M63 Disorders of muscles	0.629	0.371
M40-M43 Deforming dorsopathies	0.629	0.371
M00-M03 Infectious arthropathies	0.629	0.371
Z85.5 Personal history of malignant neoplasm of urinary tract	0.628	0.372
R68 Other general symptoms and signs	0.626	0.374
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.626	0.374
R62 Lack of expected normal physiological development	0.626	0.374
R61 Hyperhidrosis	0.626	0.374
R60 Oedema, not elsewhere classified	0.626	0.374
R59 Enlarged lymph nodes	0.626	0.374
R57 Shock, not elsewhere classified	0.626	0.374
R56 Convulsions, not elsewhere classified	0.626	0.374
R52 Pain, not elsewhere classified	0.626	0.374
R64 Cachexia	0.626	0.374
R58 Haemorrhage, not elsewhere classified	0.626	0.374
R54 Senility	0.626	0.374
R51 Headache	0.625	0.374
Z51.8 Other specified medical care	0.624	0.376
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.624	0.376
R63 Symptoms and signs concerning food and fluid intake	0.623	0.377
Z13 Special screening examination for other diseases and disorders	0.621	0.378
C43-C44 Melanoma and other malignant neoplasms of skin	0.620	0.380
I52 Other heart disorders in diseases classified elsewhere	0.619	0.381
I49 Other cardiac arrhythmias	0.619	0.381
I48 Atrial fibrillation and flutter	0.619	0.381
I46 Cardiac arrest	0.619	0.381
I45 Other conduction disorders	0.619	0.381
I44 Atrioventricular and left bundle-branch block	0.619	0.381
I43 Cardiomyopathy in diseases classified elsewhere	0.619	0.381
I42 Cardiomyopathy	0.619	0.381
I41 Myocarditis in diseases classified elsewhere	0.619	0.381
I40 Acute myocarditis	0.619	0.381
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.619	0.381
I37 Pulmonary valve disorders	0.619	0.381
I36 Nonrheumatic tricuspid valve disorders	0.619	0.381
I35 Nonrheumatic aortic valve disorders	0.619	0.381
I34 Nonrheumatic mitral valve disorders	0.619	0.381
I33 Acute and subacute endocarditis	0.619	0.381
I32 Pericarditis in diseases classified elsewhere	0.619	0.381
I31 Other diseases of pericardium	0.619	0.381
I30 Acute pericarditis	0.619	0.381
I38 Endocarditis, valve unspecified	0.619	0.381
Z09.0 Follow-up examination after surgery for other conditions	0.618	0.382
Z72 Problems related to lifestyle	0.618	0.382
Z85.3 Personal history of malignant neoplasm of breast	0.617	0.383
Z92 Personal history of medical treatment	0.617	0.383
N84 Polyp of female genital tract	0.615	0.385
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.615	0.385
Z90.4 Acquired absence of other parts of digestive tract	0.614	0.386
R05 Cough	0.612	0.388
I51 Complications and ill-defined descriptions of heart disease	0.611	0.388
Z88.0 Personal history of allergy to penicillin	0.611	0.389
Z09.2 Follow-up examination after chemotherapy for other conditions	0.610	0.390
O00-O08 Pregnancy with abortive outcome	0.609	0.390
I50.9 Heart failure, unspecified	0.609	0.391
C18 Malignant neoplasm of colon	0.605	0.395
I50.1 Left ventricular failure	0.605	0.395
C60-C63 Malignant neoplasms of male genital organs	0.604	0.396
L00-L08 Infections of the skin and subcutaneous tissue	0.604	0.396
N81 Female genital prolapse	0.602	0.398
N32 Other disorders of bladder	0.602	0.398
Z51.0 Radiotherapy session	0.601	0.399
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.600	0.400
M17 Gonarthrosis [arthrosis of knee]	0.598	0.402
T88 Other complications of surgical and medical care, not elsewhere classified	0.595	0.405
T87 Complications peculiar to reattachment and amputation	0.595	0.405
T86 Failure and rejection of transplanted organs and tissues	0.595	0.405
T85 Complications of other internal prosthetic devices, implants and grafts	0.595	0.405
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.595	0.405
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.595	0.405
T80 Complications following infusion, transfusion and therapeutic injection	0.595	0.405
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.595	0.405
Z30 Contraceptive management	0.594	0.405
N17 Acute renal failure	0.594	0.406
E66.8 Other obesity	0.594	0.406
E66.2 Extreme obesity with alveolar hypoventilation	0.594	0.406
E66.1 Drug-induced obesity	0.594	0.406
E66.0 Obesity due to excess calories	0.594	0.406
R42 Dizziness and giddiness	0.593	0.407
I21.1 Acute transmural myocardial infarction of inferior wall	0.593	0.407
N37 Urethral disorders in diseases classified elsewhere	0.592	0.408
N36 Other disorders of urethra	0.592	0.408
N34 Urethritis and urethral syndrome	0.592	0.408
N33 Bladder disorders in diseases classified elsewhere	0.592	0.408
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.592	0.408
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.591	0.409
E87.7 Fluid overload	0.591	0.409
E87.5 Hyperkalaemia	0.591	0.409
E87.4 Mixed disorder of acid-base balance	0.591	0.409
E87.3 Alkalosis	0.591	0.409
E87.0 Hyperosmolality and hypernatraemia	0.591	0.409
Z96.0 Presence of urogenital implants	0.590	0.410
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.590	0.410
I78 Diseases of capillaries	0.590	0.410
I74 Arterial embolism and thrombosis	0.590	0.410
I72 Other aneurysm	0.590	0.410
I71 Aortic aneurysm and dissection	0.590	0.410
I70 Atherosclerosis	0.590	0.410
D60-D64 Aplastic and other anaemias	0.588	0.412
R30 Pain associated with micturition	0.588	0.412
W00-W19 Falls	0.588	0.412
N80 Endometriosis	0.587	0.413
N51 Disorders of male genital organs in diseases classified elsewhere	0.587	0.413
N50 Other disorders of male genital organs	0.587	0.413
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.587	0.413
N48 Other disorders of penis	0.587	0.413
N45 Orchitis and epididymitis	0.587	0.413
N42 Other disorders of prostate	0.587	0.413
N41 Inflammatory diseases of prostate	0.587	0.413
N47 Redundant prepuce, phimosis and paraphimosis	0.587	0.413
N46 Male infertility	0.587	0.413
N44 Torsion of testis	0.587	0.413
I63 Cerebral infarction	0.587	0.413
L80-L99 Other disorders of the skin and subcutaneous tissue	0.586	0.414
G50-G59 Nerve, nerve root and plexus disorders	0.585	0.415
Z12 Special screening examination for neoplasms	0.583	0.417
Z86 Personal history of certain other diseases	0.583	0.417
G80-G83 Cerebral palsy and other paralytic syndromes	0.583	0.417
Z90.7 Acquired absence of genital organ(s)	0.582	0.418
E14 Unspecified diabetes mellitus	0.581	0.419
E13 Other specified diabetes mellitus	0.581	0.419
E12 Malnutrition-related diabetes mellitus	0.581	0.419
I20.9 Angina pectoris, unspecified	0.578	0.422
O94-O99 Other obstetric conditions, not elsewhere classified	0.576	0.424
O85-O92 Complications predominantly related to the puerperium	0.576	0.424
O80-O84 Delivery	0.576	0.424
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.576	0.424
O20-O29 Other maternal disorders predominantly related to pregnancy	0.576	0.424
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.576	0.424
I21.X Presumed acute myicardial infaction (unconfirmed)	0.574	0.426
I21.4 Acute subendocardial myocardial infarction	0.574	0.426
I21.3 Acute transmural myocardial infarction of unspecified site	0.574	0.426
I21.2 Acute transmural myocardial infarction of other sites	0.574	0.426
I21.0 Acute transmural myocardial infarction of anterior wall	0.574	0.426
N35 Urethral stricture	0.573	0.427
R55 Syncope and collapse	0.572	0.428
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.572	0.428
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.572	0.428
Y60-Y69 Misadventures to patients during surgical and medical care	0.572	0.428
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.572	0.428
Y35-Y36 Legal intervention and operations of war	0.572	0.428
Y10-Y34 Event of undetermined intent	0.572	0.428
Y00-Y09 Assault	0.572	0.428
X85-X99 Assault	0.572	0.428
X60-X84 Intentional self-harm	0.572	0.428
X58-X59 Accidental exposure to other and unspecified factors	0.572	0.428
X50-X57 Overexertion, travel and privation	0.572	0.428
X40-X49 Accidental poisoning by and exposure to noxious substances	0.572	0.428
X30-X39 Exposure to forces of nature	0.572	0.428
X20-X29 Contact with venomous animals and plants	0.572	0.428
X10-X19 Contact with heat and hot substances	0.572	0.428
X00-X09 Exposure to smoke, fire and flames	0.572	0.428
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.572	0.428
W75-W84 Other accidental threats to breathing	0.572	0.428
W65-W74 Accidental drowning and submersion	0.572	0.428
W50-W64 Exposure to animate mechanical forces	0.572	0.428
W20-W49 Exposure to inanimate mechanical forces	0.572	0.428
V98-V99 Other and unspecified transport accidents	0.572	0.428
V95-V97 Air and space transport accidents	0.572	0.428
V90-V94 Water transport accidents	0.572	0.428
V80-V89 Other land transport accidents	0.572	0.428
V70-V79 Bus occupant injured in transport accident	0.572	0.428
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.572	0.428
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.572	0.428
V40-V49 Car occupant injured in transport accident	0.572	0.428
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.572	0.428
V20-V29 Motorcycle rider injured in transport accident	0.572	0.428
V10-V19 Pedal cyclist injured in transport accident	0.572	0.428
V01-V09 Pedestrian injured in transport accident	0.572	0.428
Z87.1 Personal history of diseases of the digestive system	0.571	0.429
D50-D53 Nutritional anaemias	0.569	0.431
N13 Obstructive and reflux uropathy	0.569	0.431
I77.1 Stricture of artery	0.567	0.433
E07 Other disorders of thyroid	0.567	0.433
E06 Thyroiditis	0.567	0.433
E05 Thyrotoxicosis [hyperthyroidism]	0.567	0.433
E04 Other non-toxic goitre	0.567	0.433
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.567	0.433
E00 Congenital iodine-deficiency syndrome	0.567	0.433
E02 Subclinical iodine-deficiency hypothyroidism	0.567	0.433
C67 Malignant neoplasm of bladder	0.563	0.437
I20.8 Other forms of angina pectoris	0.563	0.437
I20.1 Angina pectoris with documented spasm	0.563	0.437
L60-L75 Disorders of skin appendages	0.563	0.437
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.561	0.439
E78.9 Disorder of lipoprotein metabolism, unspecified	0.561	0.439
E78.8 Other disorders of lipoprotein metabolism	0.561	0.439
E78.6 Lipoprotein deficiency	0.561	0.439
E78.4 Other hyperlipidaemia	0.561	0.439
E78.3 Hyperchylomicronaemia	0.561	0.439
E78.2 Mixed hyperlipidaemia	0.561	0.439
E78.1 Pure hyperglyceridaemia	0.561	0.439
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.561	0.439
L50-L54 Urticaria and erythema	0.561	0.439
L40-L45 Papulosquamous disorders	0.561	0.439
L20-L30 Dermatitis and eczema	0.561	0.439
L10-L14 Bullous disorders	0.561	0.439
G40-G47 Episodic and paroxysmal disorders	0.560	0.440
Z01.8 Other specified special examinations	0.560	0.440
R35 Polyuria	0.559	0.440
Z42.1 Follow-up care involving plastic surgery of breast	0.559	0.441
N98 Complications associated with artificial fertilisation	0.557	0.443
N97 Female infertility	0.557	0.443
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.557	0.443
N93 Other abnormal uterine and vaginal bleeding	0.557	0.443
N91 Absent, scanty and rare menstruation	0.557	0.443
N90 Other noninflammatory disorders of vulva and perineum	0.557	0.443
N89 Other noninflammatory disorders of vagina	0.557	0.443
N88 Other noninflammatory disorders of cervix uteri	0.557	0.443
N87 Dysplasia of cervix uteri	0.557	0.443
N85 Other noninflammatory disorders of uterus, except cervix	0.557	0.443
N82 Fistulae involving female genital tract	0.557	0.443
N96 Habitual aborter	0.557	0.443
N86 Erosion and ectropion of cervix uteri	0.557	0.443
F99-F99 Unspecified mental disorder	0.556	0.444
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.556	0.444
F80-F89 Disorders of psychological development	0.556	0.444
F70-F79 Mental retardation	0.556	0.444
F60-F69 Disorders of adult personality and behaviour	0.556	0.444
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.556	0.444
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.556	0.444
F00-F09 Organic, including symptomatic, mental disorders	0.556	0.444
Z76 Persons encountering health services in other circumstances	0.556	0.444
Z75 Problems related to medical facilities and other health care	0.556	0.444
Z74 Problems related to care-provider dependency	0.556	0.444
Z73 Problems related to life-management difficulty	0.556	0.444
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.556	0.444
Z70 Counselling related to sexual attitude, behaviour and orientation	0.556	0.444
D17 Benign lipomatous neoplasm	0.556	0.444
B99-B99 Other infectious diseases	0.555	0.445
B90-B94 Sequelae of infectious and parasitic diseases	0.555	0.445
B85-B89 Pediculosis, acariasis and other infestations	0.555	0.445
B65-B83 Helminthiases	0.555	0.445
B50-B64 Protozoal diseases	0.555	0.445
B35-B49 Mycoses	0.555	0.445
B25-B34 Other viral diseases	0.555	0.445
B20-B24 Human immunodeficiency virus [HIV] disease	0.555	0.445
B15-B19 Viral hepatitis	0.555	0.445
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.555	0.445
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.555	0.445
A80-A89 Viral infections of the central nervous system	0.555	0.445
A75-A79 Rickettsioses	0.555	0.445
A70-A74 Other diseases caused by chlamydiae	0.555	0.445
A65-A69 Other spirochaetal diseases	0.555	0.445
A50-A64 Infections with a predominantly sexual mode of transmission	0.555	0.445
A20-A28 Certain zoonotic bacterial diseases	0.555	0.445
A15-A19 Tuberculosis	0.555	0.445
G90-G99 Other disorders of the nervous system	0.555	0.445
G70-G73 Diseases of myoneural junction and muscle	0.555	0.445
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.555	0.445
G35-G37 Demyelinating diseases of the central nervous system	0.555	0.445
G30-G32 Other degenerative diseases of the nervous system	0.555	0.445
G20-G26 Extrapyramidal and movement disorders	0.555	0.445
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.555	0.445
G00-G09 Inflammatory diseases of the central nervous system	0.555	0.445
Z93.9 Artificial opening status, unspecified	0.553	0.446
Z93.8 Other artificial opening status	0.553	0.446
Z93.6 Other artificial openings of urinary tract status	0.553	0.446
Z93.5 Cystostomy status	0.553	0.446
Z93.4 Other artificial openings of gastro-intestinal tract status	0.553	0.446
Z93.3 Colostomy status	0.553	0.446

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations