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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2288017
log Bayes Factor = 12.487
Chromosome 16   position 84,793,749  (GRCh37) Explore rs2288017 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
M23 Internal derangement of knee
0.990 0.010 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
N30-N39 Other diseases of urinary system
0.986 0.014 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.984 0.016 0.000
N30 Cystitis
0.977 0.023 0.000
M79.6 Pain in limb
0.977 0.023 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
M23.3 Other meniscus derangements
0.969 0.031 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
Chapter IX Diseases of the circulatory system
0.956 0.044 0.000
I73 Other peripheral vascular diseases
0.953 0.047 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.953 0.047 0.000
O20 Haemorrhage in early pregnancy
0.948 0.052 0.000
I73.9 Peripheral vascular disease, unspecified
0.943 0.057 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.928 0.072 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.927 0.073 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.925 0.075 0.000
Chapter VII Diseases of the eye and adnexa
0.922 0.078 0.000
I71 Aortic aneurysm and dissection
0.921 0.079 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.920 0.080 0.000
M25 Other joint disorders, not elsewhere classified
0.918 0.082 0.000
M24 Other specific joint derangements
0.917 0.083 0.000
M45-M49 Spondylopathies
0.915 0.085 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.914 0.086 0.000
Chapter I Certain infectious and parasitic diseases
0.907 0.093 0.000
N00-N08 Glomerular diseases
0.906 0.094 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.906 0.094 0.000
M79.66 Pain in limb (Lower leg)
0.905 0.095 0.000
M79.67 Pain in limb (Ankle and foot)
0.904 0.096 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.904 0.096 0.000
M79.60 Pain in limb (Multiple sites)
0.899 0.101 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.897 0.103 0.000
S00-S09 Injuries to the head
0.896 0.104 0.000
N10-N16 Renal tubulo-interstitial diseases
0.895 0.105 0.000
Chapter XXII Codes for special purposes
0.893 0.107 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.891 0.109 0.000
M22 Disorders of patella
0.888 0.112 0.000
O26.8 Other specified pregnancy-related conditions
0.886 0.114 0.000
N30.2 Other chronic cystitis
0.886 0.114 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.885 0.115 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.881 0.119 0.000
N30.1 Interstitial cystitis (chronic)
0.877 0.123 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.873 0.127 0.000
L50-L54 Urticaria and erythema
0.872 0.128 0.000
O20.0 Threatened abortion
0.871 0.129 0.000
S70-S79 Injuries to the hip and thigh
0.868 0.132 0.000
N17-N19 Renal failure
0.868 0.132 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.866 0.134 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.865 0.135 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.860 0.140 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.859 0.141 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.859 0.141 0.000
T66-T78 Other and unspecified effects of external causes
0.857 0.143 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.857 0.143 0.000
Chapter V Mental and behavioural disorders
0.856 0.144 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.853 0.147 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.852 0.148 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.851 0.149 0.000
M47 Spondylosis
0.851 0.149 0.000
W20-W49 Exposure to inanimate mechanical forces
0.850 0.150 0.000
M50-M54 Other dorsopathies
0.847 0.152 0.000
S01 Open wound of head
0.846 0.154 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.846 0.154 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.843 0.157 0.000
N03 Chronic nephritic syndrome
0.839 0.161 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.838 0.162 0.000
W00-W19 Falls
0.836 0.164 0.000
N30.9 Cystitis, unspecified
0.833 0.167 0.000
H43-H45 Disorders of vitreous body and globe
0.826 0.174 0.000
M47.8 Other spondylosis
0.826 0.174 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.826 0.174 0.000
M25.4 Effusion of joint
0.825 0.175 0.000
M21 Other acquired deformities of limbs
0.824 0.176 0.000
S80-S89 Injuries to the knee and lower leg
0.822 0.178 0.000
M77 Other enthesopathies
0.820 0.180 0.000
M54 Dorsalgia
0.819 0.181 0.000
N99-N99 Other disorders of the genitourinary system
0.817 0.183 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.817 0.183 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
S90-S99 Injuries to the ankle and foot
0.806 0.194 0.000
L81 Other disorders of pigmentation
0.806 0.194 0.000
L03 Cellulitis
0.805 0.195 0.000
S20-S29 Injuries to the thorax
0.805 0.195 0.000
S01.8 Open wound of other parts of head
0.805 0.195 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.804 0.196 0.000
M80-M85 Disorders of bone density and structure
0.804 0.196 0.000
I73.0 Raynaud's syndrome
0.803 0.197 0.000
T87 Complications peculiar to reattachment and amputation
0.801 0.199 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.801 0.199 0.000
N34 Urethritis and urethral syndrome
0.799 0.201 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.799 0.201 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.796 0.204 0.000
M24.1 Other articular cartilage disorders
0.796 0.204 0.000
S40-S49 Injuries to the shoulder and upper arm
0.795 0.205 0.000
I77 Other disorders of arteries and arterioles
0.792 0.208 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.792 0.208 0.000
M54.5 Low back pain
0.792 0.208 0.000
N36 Other disorders of urethra
0.791 0.209 0.000
Q60-Q64 Congenital malformations of the urinary system
0.791 0.209 0.000
N03.9 Unspecified
0.791 0.209 0.000
F03 Unspecified dementia
0.790 0.210 0.000
N30.3 Trigonitis
0.790 0.210 0.000
I74 Arterial embolism and thrombosis
0.788 0.212 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.787 0.213 0.000
H44 Disorders of globe
0.787 0.213 0.000
M71 Other bursopathies
0.787 0.213 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.785 0.214 0.000
O80-O84 Delivery
0.785 0.215 0.000
M47.82 Other spondylosis (Cervical region)
0.783 0.217 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.783 0.217 0.000
M24.0 Loose body in joint
0.783 0.217 0.000
M31 Other necrotising vasculopathies
0.779 0.221 0.000
M79.9 Soft tissue disorder, unspecified
0.777 0.222 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.777 0.223 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.776 0.224 0.000
N30.4 Irradiation cystitis
0.776 0.224 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.775 0.225 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.775 0.225 0.000
W22 Striking against or struck by other objects
0.774 0.226 0.000
M22.2 Patellofemoral disorders
0.774 0.226 0.000
H21 Other disorders of iris and ciliary body
0.771 0.229 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.770 0.229 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.769 0.231 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.765 0.235 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.764 0.235 0.000
M76 Enthesopathies of lower limb, excluding foot
0.764 0.236 0.000
L53 Other erythematous conditions
0.764 0.236 0.000
A30-A49 Other bacterial diseases
0.763 0.237 0.000
I71.0 Dissection of aorta [any part]
0.763 0.237 0.000
Chapter X Diseases of the respiratory system
0.763 0.237 0.000
N30.0 Acute cystitis
0.762 0.238 0.000
T93 Sequelae of injuries of lower limb
0.762 0.238 0.000
M34 Systemic sclerosis
0.762 0.238 0.000
V10-V19 Pedal cyclist injured in transport accident
0.761 0.238 0.000
M79.7 Fibromyalgia
0.761 0.239 0.000
L03.2 Cellulitis of face
0.760 0.240 0.000
N18 Chronic renal failure
0.758 0.242 0.000
S70 Superficial injury of hip and thigh
0.757 0.243 0.000
N25-N29 Other disorders of kidney and ureter
0.757 0.243 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.757 0.243 0.000
N40-N51 Diseases of male genital organs
0.757 0.243 0.000
M46 Other inflammatory spondylopathies
0.756 0.244 0.000
J95-J99 Other diseases of the respiratory system
0.756 0.244 0.000
H44.2 Degenerative myopia
0.754 0.246 0.000
B95-B98 Bacterial, viral and other infectious agents
0.753 0.247 0.000
M00-M03 Infectious arthropathies
0.752 0.247 0.000
J98 Other respiratory disorders
0.752 0.248 0.000
M25.7 Osteophyte
0.751 0.249 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.751 0.249 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.750 0.250 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.748 0.252 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.748 0.252 0.000
M75 Shoulder lesions
0.746 0.254 0.000
J98.1 Pulmonary collapse
0.746 0.254 0.000
V80-V89 Other land transport accidents
0.745 0.255 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.743 0.257 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.741 0.259 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.741 0.259 0.000
T78 Adverse effects, not elsewhere classified
0.740 0.260 0.000
Y83.8 Other surgical procedures
0.739 0.261 0.000
M79.2 Neuralgia and neuritis, unspecified
0.739 0.261 0.000
L84 Corns and callosities
0.738 0.262 0.000
I70 Atherosclerosis
0.736 0.264 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.733 0.267 0.000
I72 Other aneurysm
0.732 0.268 0.000
O85-O92 Complications predominantly related to the puerperium
0.731 0.268 0.000
L82 Seborrhoeic keratosis
0.731 0.269 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.729 0.271 0.000
N73 Other female pelvic inflammatory diseases
0.728 0.271 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.728 0.272 0.000
N17 Acute renal failure
0.728 0.272 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.727 0.272 0.000
M35 Other systemic involvement of connective tissue
0.726 0.274 0.000
A15-A19 Tuberculosis
0.724 0.276 0.000
T86 Failure and rejection of transplanted organs and tissues
0.724 0.276 0.000
M79.1 Myalgia
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.723 0.277 0.000
S02 Fracture of skull and facial bones
0.723 0.277 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.723 0.277 0.000
M40-M43 Deforming dorsopathies
0.723 0.277 0.000
M25.46 Effusion of joint (Lower leg)
0.721 0.279 0.000
D68 Other coagulation defects
0.721 0.279 0.000
W22.9 Unspecified place
0.720 0.280 0.000
U80 Agent resistant to penicillin and related antibiotics
0.719 0.281 0.000
M54.56 Low back pain (Lumbar region)
0.718 0.282 0.000
T81 Complications of procedures, not elsewhere classified
0.718 0.282 0.000
Q61 Cystic kidney disease
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M23.8 Other internal derangements of knee
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
O60-O75 Complications of labour and delivery
0.715 0.285 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.714 0.286 0.000
S01.2 Open wound of nose
0.714 0.286 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.713 0.287 0.000
Chapter XXI Factors influencing health status and contact with health services
0.713 0.287 0.000
N30.8 Other cystitis
0.712 0.288 0.000
L81.4 Other melanin hyperpigmentation
0.711 0.289 0.000
N10 Acute tubulo-interstitial nephritis
0.710 0.289 0.000
H30-H36 Disorders of choroid and retina
0.710 0.290 0.000
M23.9 Internal derangement of knee, unspecified
0.710 0.290 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.710 0.290 0.000
M23.5 Chronic instability of knee
0.710 0.290 0.000
M23.1 Discoid meniscus (congenital)
0.710 0.290 0.000
M23.0 Cystic meniscus
0.710 0.290 0.000
H20 Iridocyclitis
0.710 0.290 0.000
M54.9 Dorsalgia, unspecified
0.710 0.290 0.000
M65-M68 Disorders of synovium and tendon
0.708 0.292 0.000
M20 Acquired deformities of fingers and toes
0.708 0.292 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.707 0.292 0.000
M79.3 Panniculitis, unspecified
0.707 0.292 0.000
N18.3 Chronic kidney disease, stage 3
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
N37 Urethral disorders in diseases classified elsewhere
0.707 0.293 0.000
N33 Bladder disorders in diseases classified elsewhere
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
O29 Complications of anaesthesia during pregnancy
0.705 0.294 0.000
O28 Abnormal findings on antenatal screening of mother
0.705 0.294 0.000
O24 Diabetes mellitus in pregnancy
0.705 0.294 0.000
O22 Venous complications in pregnancy
0.705 0.294 0.000
O25 Malnutrition in pregnancy
0.705 0.294 0.000
O23 Infections of genito-urinary tract in pregnancy
0.705 0.295 0.000
M25.77 Osteophyte (Ankle and foot)
0.705 0.295 0.000
M54.57 Low back pain (Lumbosacral region)
0.704 0.296 0.000
O00-O08 Pregnancy with abortive outcome
0.704 0.296 0.000
M86-M90 Other osteopathies
0.704 0.296 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.703 0.297 0.000
W08 Fall involving other furniture
0.701 0.299 0.000
M79.0 Rheumatism, unspecified
0.701 0.299 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.701 0.299 0.000
M79.68 Pain in limb (Other)
0.700 0.300 0.000
M79.63 Pain in limb (Forearm)
0.700 0.300 0.000
M79.61 Pain in limb (Shoulder region)
0.700 0.300 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.697 0.302 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
L20-L30 Dermatitis and eczema
0.697 0.303 0.000
M23.37 Other meniscus derangements-Capsular lig
0.694 0.305 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.694 0.305 0.000
M22.4 Chondromalacia patellae
0.693 0.307 0.000
L93 Lupus erythematosus
0.692 0.307 0.000
L52 Erythema nodosum
0.692 0.307 0.000
M47.86 Other spondylosis (Lumbar region)
0.692 0.308 0.000
O80 Single spontaneous delivery
0.690 0.310 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.688 0.312 0.000
M24.07 Loose body in joint (Ankle and foot)
0.686 0.314 0.000
L53.9 Erythematous condition, unspecified
0.686 0.314 0.000
M72 Fibroblastic disorders
0.686 0.314 0.000
I00-I02 Acute rheumatic fever
0.686 0.314 0.000
S01.0 Open wound of scalp
0.685 0.315 0.000
I73.8 Other specified peripheral vascular diseases
0.684 0.316 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.684 0.316 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.683 0.317 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.683 0.317 0.000
H55-H59 Other disorders of eye and adnexa
0.683 0.317 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.683 0.317 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.683 0.317 0.000
O21 Excessive vomiting in pregnancy
0.683 0.317 0.000
H21.8 Other specified disorders of iris and ciliary body
0.683 0.317 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
M70.7 Other bursitis of hip
0.682 0.318 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.682 0.318 0.000
O20.8 Other haemorrhage in early pregnancy
0.680 0.320 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.679 0.321 0.000
J98.4 Other disorders of lung
0.679 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.321 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.678 0.322 0.000
M70.6 Trochanteric bursitis
0.678 0.322 0.000
N73.6 Female pelvic peritoneal adhesions
0.678 0.322 0.000
A80-A89 Viral infections of the central nervous system
0.678 0.322 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.677 0.323 0.000
I78 Diseases of capillaries
0.677 0.323 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.676 0.324 0.000
S82 Fracture of lower leg, including ankle
0.676 0.324 0.000
M25.0 Haemarthrosis
0.676 0.324 0.000
S79 Other and unspecified injuries of hip and thigh
0.675 0.324 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.675 0.325 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.675 0.325 0.000
F01 Vascular dementia
0.674 0.326 0.000
Y83.5 Amputation of limb(s)
0.673 0.327 0.000
M79.8 Other specified soft tissue disorders
0.673 0.327 0.000
W05 Fall involving wheelchair
0.672 0.328 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.671 0.329 0.000
T93.2 Sequelae of other fractures of lower limb
0.671 0.329 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.670 0.329 0.000
W07 Fall involving chair
0.670 0.330 0.000
M77.9 Enthesopathy, unspecified
0.669 0.331 0.000
F02 Dementia in other diseases classified elsewhere
0.668 0.332 0.000
M23.4 Loose body in knee
0.668 0.332 0.000
S80 Superficial injury of lower leg
0.668 0.332 0.000
N04 Nephrotic syndrome
0.667 0.333 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.667 0.333 0.000
M54.50 Low back pain (Multiple sites in spine)
0.666 0.334 0.000
N34.3 Urethral syndrome, unspecified
0.666 0.334 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.666 0.334 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.665 0.335 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.665 0.335 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.665 0.335 0.000
O26.5 Maternal hypotension syndrome
0.665 0.335 0.000
O26.4 Herpes gestationis
0.665 0.335 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.665 0.335 0.000
O26.2 Pregnancy care of habitual aborter
0.665 0.335 0.000
O26.1 Low weight gain in pregnancy
0.665 0.335 0.000
O26.0 Excessive weight gain in pregnancy
0.665 0.335 0.000
O26.9 Pregnancy-related condition, unspecified
0.664 0.336 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.664 0.336 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.663 0.336 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.663 0.336 0.000
L94 Other localised connective tissue disorders
0.663 0.336 0.000
L87 Transepidermal elimination disorders
0.663 0.336 0.000
L88 Pyoderma gangrenosum
0.663 0.336 0.000
L86 Keratoderma in diseases classified elsewhere
0.663 0.336 0.000
L83 Acanthosis nigricans
0.663 0.336 0.000
L80 Vitiligo
0.663 0.336 0.000
I30-I52 Other forms of heart disease
0.663 0.337 0.000
W21 Striking against or struck by sports equipment
0.662 0.338 0.000
N48 Other disorders of penis
0.662 0.338 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.661 0.339 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.660 0.340 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.660 0.340 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.660 0.340 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.660 0.340 0.000
M22.8 Other disorders of patella
0.660 0.340 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.659 0.341 0.000
Chapter VIII Diseases of the ear and mastoid process
0.658 0.342 0.000
M25.9 Joint disorder, unspecified
0.658 0.342 0.000
M25.3 Other instability of joint
0.658 0.342 0.000
M25.2 Flail joint
0.658 0.342 0.000
M25.1 Fistula of joint
0.658 0.342 0.000
M24.9 Joint derangement, unspecified
0.657 0.342 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.657 0.342 0.000
M24.7 Protrusio acetabuli
0.657 0.342 0.000
M24.6 Ankylosis of joint
0.657 0.342 0.000
M24.5 Contracture of joint
0.657 0.342 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.657 0.342 0.000
M24.2 Disorder of ligament
0.657 0.342 0.000
D68.2 Hereditary deficiency of other clotting factors
0.657 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.343 0.000
Q80-Q89 Other congenital malformations
0.656 0.344 0.000
M49 Spondylopathies in diseases classified elsewhere
0.656 0.344 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.655 0.345 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.655 0.345 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.654 0.346 0.000
H40-H42 Glaucoma
0.654 0.346 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.653 0.347 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.652 0.348 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.348 0.000
S50-S59 Injuries to the elbow and forearm
0.652 0.348 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.651 0.349 0.000
B99-B99 Other infectious diseases
0.650 0.350 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.650 0.350 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.650 0.350 0.000
B65-B83 Helminthiases
0.650 0.350 0.000
B50-B64 Protozoal diseases
0.650 0.350 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.650 0.350 0.000
A75-A79 Rickettsioses
0.650 0.350 0.000
A70-A74 Other diseases caused by chlamydiae
0.650 0.350 0.000
A65-A69 Other spirochaetal diseases
0.650 0.350 0.000
A20-A28 Certain zoonotic bacterial diseases
0.650 0.350 0.000
M79.5 Residual foreign body in soft tissue
0.650 0.350 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.650 0.350 0.000
N06 Isolated proteinuria with specified morphological lesion
0.650 0.350 0.000
N05 Unspecified nephritic syndrome
0.650 0.350 0.000
N01 Rapidly progressive nephritic syndrome
0.650 0.350 0.000
N00 Acute nephritic syndrome
0.650 0.350 0.000
H52 Disorders of refraction and accommodation
0.650 0.350 0.000
S82.8 Fractures of other parts of lower leg
0.649 0.350 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.649 0.351 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.648 0.352 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.648 0.352 0.000
M77.4 Metatarsalgia
0.648 0.352 0.000
L50 Urticaria
0.648 0.352 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.648 0.352 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.648 0.352 0.000
T68 Hypothermia
0.647 0.353 0.000
Z29 Need for other prophylactic measures
0.646 0.354 0.000
T90 Sequelae of injuries of head
0.646 0.354 0.000
H35 Other retinal disorders
0.646 0.354 0.000
M75.1 Rotator cuff syndrome
0.646 0.354 0.000
Q00-Q07 Congenital malformations of the nervous system
0.645 0.355 0.000
T82.3 Mechanical complication of other vascular grafts
0.645 0.355 0.000
L81.8 Other specified disorders of pigmentation
0.645 0.355 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.645 0.355 0.000
M21.1 Varus deformity, not elsewhere classified
0.644 0.356 0.000
N76 Other inflammation of vagina and vulva
0.644 0.356 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.643 0.356 0.000
J00-J06 Acute upper respiratory infections
0.643 0.357 0.000
Y83.0 Surgical operation with transplant of whole organ
0.643 0.357 0.000
S08 Traumatic amputation of part of head
0.642 0.358 0.000
S07 Crushing injury of head
0.642 0.358 0.000
S05 Injury of eye and orbit
0.642 0.358 0.000
S04 Injury of cranial nerves
0.642 0.358 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.642 0.358 0.000
T82.1 Mechanical complication of cardiac electronic device
0.642 0.358 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.642 0.358 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.642 0.358 0.000
N15 Other renal tubulo-interstitial diseases
0.642 0.358 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.642 0.358 0.000
N11 Chronic tubulo-interstitial nephritis
0.642 0.358 0.000
S10 Superficial injury of neck
0.641 0.359 0.000
T78.4 Allergy, unspecified
0.641 0.359 0.000
W17 Other fall from one level to another
0.640 0.360 0.000
N35 Urethral stricture
0.639 0.361 0.000
M48 Other spondylopathies
0.639 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.639 0.361 0.000
Q35-Q37 Cleft lip and cleft palate
0.639 0.361 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.639 0.361 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.639 0.361 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.638 0.361 0.000
T91 Sequelae of injuries of neck and trunk
0.638 0.362 0.000
F00 Dementia in Alzheimer's disease
0.637 0.362 0.000
M22.1 Recurrent subluxation of patella
0.636 0.363 0.000
M22.9 Disorder of patella, unspecified
0.636 0.363 0.000
M22.3 Other derangements of patella
0.636 0.363 0.000
M22.0 Recurrent dislocation of patella
0.636 0.363 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.636 0.364 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.636 0.364 0.000
U80.1 Methicillin resistant agent
0.636 0.364 0.000
A00-A09 Intestinal infectious diseases
0.635 0.364 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.635 0.365 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.634 0.365 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.634 0.365 0.000
L04 Acute lymphadenitis
0.634 0.366 0.000
L01 Impetigo
0.634 0.366 0.000
L00 Staphylococcal scalded skin syndrome
0.634 0.366 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.634 0.366 0.000
M25.8 Other specified joint disorders
0.634 0.366 0.000
I46 Cardiac arrest
0.633 0.367 0.000
N13 Obstructive and reflux uropathy
0.632 0.368 0.000
F80-F89 Disorders of psychological development
0.631 0.368 0.000
T87.6 Other and unspecified complications of amputation stump
0.631 0.369 0.000
L03.9 Cellulitis, unspecified
0.631 0.369 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.631 0.369 0.000
A41 Other septicaemia
0.630 0.370 0.000
T58 Toxic effect of carbon monoxide
0.630 0.370 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.628 0.372 0.000
L08 Other local infections of skin and subcutaneous tissue
0.628 0.372 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.628 0.372 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.627 0.372 0.000
N02 Recurrent and persistent haematuria
0.626 0.374 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.626 0.374 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.626 0.374 0.000
L98.5 Mucinosis of skin
0.626 0.374 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.626 0.374 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.626 0.374 0.000
L98.1 Factitial dermatitis
0.626 0.374 0.000
L54 Erythema in diseases classified elsewhere
0.625 0.375 0.000
L51 Erythema multiforme
0.625 0.375 0.000
B35-B49 Mycoses
0.625 0.375 0.000
T87.4 Infection of amputation stump
0.624 0.376 0.000
I05-I09 Chronic rheumatic heart diseases
0.623 0.377 0.000
S00 Superficial injury of head
0.623 0.377 0.000
M85 Other disorders of bone density and structure
0.623 0.377 0.000
S78 Traumatic amputation of hip and thigh
0.622 0.378 0.000
S77 Crushing injury of hip and thigh
0.622 0.378 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.622 0.378 0.000
S75 Injury of blood vessels at hip and thigh level
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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