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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79274317
log Bayes Factor = 9.38319
Chromosome 16   position 7,354,883  (GRCh37) Explore rs79274317 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
A30-A49 Other bacterial diseases
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
I77 Other disorders of arteries and arterioles
0.987 0.013 0.000
A41 Other septicaemia
0.982 0.018 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.981 0.019 0.000
Z45 Adjustment and management of implanted device
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.978 0.022 0.000
G40-G47 Episodic and paroxysmal disorders
0.975 0.025 0.000
G47 Sleep disorders
0.972 0.028 0.000
M70-M79 Other soft tissue disorders
0.971 0.029 0.000
Chapter II Neoplasms
0.969 0.031 0.000
M75 Shoulder lesions
0.966 0.034 0.000
G47.3 Sleep apnoea
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
G81 Hemiplegia
0.955 0.045 0.000
I67 Other cerebrovascular diseases
0.952 0.048 0.000
Z42 Follow-up care involving plastic surgery
0.951 0.049 0.000
I77.1 Stricture of artery
0.949 0.051 0.000
I69 Sequelae of cerebrovascular disease
0.946 0.054 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.945 0.055 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.940 0.060 0.000
I73 Other peripheral vascular diseases
0.938 0.062 0.000
M75.5 Bursitis of shoulder
0.938 0.062 0.000
G81.9 Hemiplegia, unspecified
0.937 0.063 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.934 0.066 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.933 0.067 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.929 0.071 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.925 0.075 0.000
M75.0 Adhesive capsulitis of shoulder
0.921 0.079 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.920 0.080 0.000
I51 Complications and ill-defined descriptions of heart disease
0.915 0.085 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.914 0.086 0.000
Z49 Care involving dialysis
0.912 0.088 0.000
D60-D64 Aplastic and other anaemias
0.903 0.097 0.000
C51-C58 Malignant neoplasms of female genital organs
0.902 0.098 0.000
E20-E35 Disorders of other endocrine glands
0.901 0.099 0.000
I38 Endocarditis, valve unspecified
0.900 0.100 0.000
Z51 Other medical care
0.899 0.101 0.000
B25-B34 Other viral diseases
0.896 0.104 0.000
Z50 Care involving use of rehabilitation procedures
0.893 0.107 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.890 0.110 0.000
B35-B49 Mycoses
0.887 0.113 0.000
Z51.3 Blood transfusion without reported diagnosis
0.881 0.119 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.878 0.122 0.000
Z53.9 Procedure not carried out, unspecified reason
0.878 0.122 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.877 0.123 0.000
C56 Malignant neoplasm of ovary
0.877 0.123 0.000
I51.9 Heart disease, unspecified
0.870 0.130 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.868 0.132 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.863 0.137 0.000
C32 Malignant neoplasm of larynx
0.860 0.140 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.858 0.142 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.858 0.142 0.000
A40 Streptococcal septicaemia
0.858 0.142 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.857 0.143 0.000
M05-M14 Inflammatory polyarthropathies
0.857 0.143 0.000
I74 Arterial embolism and thrombosis
0.854 0.146 0.000
I65.2 Occlusion and stenosis of carotid artery
0.850 0.150 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.845 0.155 0.000
D50-D53 Nutritional anaemias
0.844 0.155 0.000
I42 Cardiomyopathy
0.844 0.156 0.000
C34 Malignant neoplasm of bronchus and lung
0.841 0.159 0.000
I73.0 Raynaud's syndrome
0.841 0.159 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.841 0.159 0.000
Chapter XXII Codes for special purposes
0.840 0.160 0.000
I67.1 Cerebral aneurysm, nonruptured
0.840 0.160 0.000
I67.8 Other specified cerebrovascular diseases
0.838 0.162 0.000
I44 Atrioventricular and left bundle-branch block
0.837 0.163 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.837 0.163 0.000
Z29 Need for other prophylactic measures
0.837 0.163 0.000
D69 Purpura and other haemorrhagic conditions
0.834 0.166 0.000
G47.9 Sleep disorder, unspecified
0.833 0.167 0.000
D64 Other anaemias
0.833 0.167 0.000
Z45.1 Adjustment and management of infusion pump
0.832 0.168 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.831 0.169 0.000
G83 Other paralytic syndromes
0.829 0.171 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.826 0.174 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.825 0.175 0.000
I73.9 Peripheral vascular disease, unspecified
0.822 0.178 0.000
I51.7 Cardiomegaly
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
Chapter VIII Diseases of the ear and mastoid process
0.816 0.184 0.000
I69.3 Sequelae of cerebral infarction
0.816 0.184 0.000
Z45.2 Adjustment and management of vascular access device
0.814 0.186 0.000
B99-B99 Other infectious diseases
0.813 0.187 0.000
I77.8 Other specified disorders of arteries and arterioles
0.810 0.190 0.000
Z49.1 Extracorporeal dialysis
0.809 0.191 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.809 0.191 0.000
C01 Malignant neoplasm of base of tongue
0.808 0.192 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.806 0.194 0.000
M77 Other enthesopathies
0.803 0.197 0.000
I67.2 Cerebral atherosclerosis
0.800 0.200 0.000
M40-M43 Deforming dorsopathies
0.799 0.201 0.000
E50-E64 Other nutritional deficiencies
0.798 0.202 0.000
Z47 Other orthopaedic follow-up care
0.795 0.205 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.795 0.205 0.000
A41.8 Other specified septicaemia
0.794 0.206 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.792 0.208 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
D51 Vitamin B12 deficiency anaemia
0.790 0.210 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.789 0.211 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.788 0.212 0.000
I34 Nonrheumatic mitral valve disorders
0.788 0.212 0.000
H90-H95 Other disorders of ear
0.788 0.212 0.000
Z50.5 Speech therapy
0.784 0.216 0.000
I50 Heart failure
0.783 0.217 0.000
Chapter XX External causes of morbidity and mortality
0.782 0.218 0.000
I70 Atherosclerosis
0.782 0.218 0.000
Z52 Donors of organs and tissues
0.778 0.222 0.000
C92 Myeloid leukaemia
0.776 0.224 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.776 0.224 0.000
E21.3 Hyperparathyroidism, unspecified
0.774 0.226 0.000
I77.6 Arteritis, unspecified
0.771 0.229 0.000
B25 Cytomegaloviral disease
0.770 0.229 0.000
Chapter X Diseases of the respiratory system
0.770 0.230 0.000
B65-B83 Helminthiases
0.770 0.230 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.768 0.232 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.768 0.232 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.768 0.232 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.768 0.232 0.000
I60 Subarachnoid haemorrhage
0.767 0.233 0.000
G82 Paraplegia and tetraplegia
0.767 0.233 0.000
D68 Other coagulation defects
0.766 0.234 0.000
C32.1 Supraglottis
0.766 0.234 0.000
G62 Other polyneuropathies
0.766 0.234 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.766 0.234 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.766 0.234 0.000
M10 Gout
0.766 0.234 0.000
Z51.1 Chemotherapy session for neoplasm
0.763 0.237 0.000
C34.1 Upper lobe, bronchus or lung
0.763 0.237 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
A46 Erysipelas
0.761 0.239 0.000
M75.4 Impingement syndrome of shoulder
0.758 0.242 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.758 0.242 0.000
E10-E14 Diabetes mellitus
0.758 0.242 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.757 0.243 0.000
I05-I09 Chronic rheumatic heart diseases
0.757 0.243 0.000
I42.0 Dilated cardiomyopathy
0.756 0.244 0.000
E23 Hypofunction and other disorders of pituitary gland
0.756 0.244 0.000
Z49.0 Preparatory care for dialysis
0.756 0.244 0.000
D80-D89 Certain disorders involving the immune mechanism
0.755 0.245 0.000
Z29.2 Other prophylactic chemotherapy
0.755 0.245 0.000
H90 Conductive and sensorineural hearing loss
0.754 0.246 0.000
I33 Acute and subacute endocarditis
0.753 0.246 0.000
B34 Viral infection of unspecified site
0.747 0.253 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.747 0.253 0.000
D64.9 Anaemia, unspecified
0.746 0.254 0.000
B37 Candidiasis
0.746 0.254 0.000
M75.9 Shoulder lesion, unspecified
0.745 0.254 0.000
D69.6 Thrombocytopenia, unspecified
0.742 0.258 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.741 0.258 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.741 0.259 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.740 0.260 0.000
I50.9 Heart failure, unspecified
0.738 0.262 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.735 0.265 0.000
Z75 Problems related to medical facilities and other health care
0.733 0.267 0.000
G20-G26 Extrapyramidal and movement disorders
0.733 0.267 0.000
M75.3 Calcific tendinitis of shoulder
0.732 0.268 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.732 0.268 0.000
E34 Other endocrine disorders
0.731 0.269 0.000
C34.3 Lower lobe, bronchus or lung
0.731 0.269 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.729 0.271 0.000
Z51.6 Desensitisation to allergens
0.728 0.272 0.000
I44.1 Atrioventricular block, second degree
0.727 0.273 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.725 0.274 0.000
E27 Other disorders of adrenal gland
0.725 0.275 0.000
I74.5 Embolism and thrombosis of iliac artery
0.725 0.275 0.000
I44.2 Atrioventricular block, complete
0.725 0.275 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.723 0.277 0.000
C05 Malignant neoplasm of palate
0.723 0.277 0.000
G83.4 Cauda equina syndrome
0.721 0.279 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.719 0.281 0.000
D00-D09 In situ neoplasms
0.719 0.281 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.718 0.282 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.282 0.000
D41.4 Bladder
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
C32.9 Larynx, unspecified
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
I72 Other aneurysm
0.715 0.285 0.000
A48 Other bacterial diseases, not elsewhere classified
0.711 0.289 0.000
A44 Bartonellosis
0.711 0.289 0.000
A43 Nocardiosis
0.711 0.289 0.000
A42 Actinomycosis
0.711 0.289 0.000
A39 Meningococcal infection
0.711 0.289 0.000
A37 Whooping cough
0.711 0.289 0.000
A36 Diphtheria
0.711 0.289 0.000
A32 Listeriosis
0.711 0.289 0.000
A31 Infection due to other mycobacteria
0.711 0.289 0.000
A30 Leprosy [Hansen's disease]
0.711 0.289 0.000
A38 Scarlet fever
0.711 0.289 0.000
A35 Other tetanus
0.711 0.289 0.000
A34 Obstetrical tetanus
0.711 0.289 0.000
A33 Tetanus neonatorum
0.711 0.289 0.000
D69.5 Secondary thrombocytopenia
0.711 0.289 0.000
M72 Fibroblastic disorders
0.710 0.290 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.292 0.000
I77.5 Necrosis of artery
0.708 0.292 0.000
I77.4 Coeliac artery compression syndrome
0.708 0.292 0.000
I77.3 Arterial fibromuscular dysplasia
0.708 0.292 0.000
I77.2 Rupture of artery
0.708 0.292 0.000
I77.0 Arteriovenous fistula, acquired
0.708 0.292 0.000
C10 Malignant neoplasm of oropharynx
0.707 0.293 0.000
C04 Malignant neoplasm of floor of mouth
0.706 0.293 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
M13 Other arthritis
0.704 0.295 0.000
A41.4 Septicaemia due to anaerobes
0.704 0.296 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.704 0.296 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.704 0.296 0.000
G80 Infantile cerebral palsy
0.704 0.296 0.000
I61 Intracerebral haemorrhage
0.703 0.297 0.000
I95 Hypotension
0.702 0.298 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.702 0.298 0.000
Z45.3 Adjustment and management of implanted hearing device
0.702 0.298 0.000
M10.9 Gout, unspecified
0.700 0.299 0.000
B15-B19 Viral hepatitis
0.700 0.299 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.698 0.302 0.000
A41.9 Septicaemia, unspecified
0.698 0.302 0.000
B35 Dermatophytosis
0.697 0.303 0.000
G47.8 Other sleep disorders
0.697 0.303 0.000
G47.4 Narcolepsy and cataplexy
0.697 0.303 0.000
G47.2 Disorders of the sleep-wake schedule
0.697 0.303 0.000
D64.8 Other specified anaemias
0.697 0.303 0.000
I62 Other nontraumatic intracranial haemorrhage
0.696 0.304 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.696 0.304 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.306 0.000
Z29.0 Isolation
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
J09-J18 Influenza and pneumonia
0.694 0.306 0.000
Z29.1 Prophylactic immunotherapy
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.693 0.307 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.689 0.310 0.000
A40.8 Other streptococcal septicaemia
0.689 0.311 0.000
I37 Pulmonary valve disorders
0.688 0.311 0.000
M75.1 Rotator cuff syndrome
0.688 0.312 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.685 0.315 0.000
G81.1 Spastic hemiplegia
0.685 0.315 0.000
G81.0 Flaccid hemiplegia
0.685 0.315 0.000
M71 Other bursopathies
0.685 0.315 0.000
A80-A89 Viral infections of the central nervous system
0.684 0.316 0.000
E29 Testicular dysfunction
0.684 0.316 0.000
M86-M90 Other osteopathies
0.683 0.317 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.682 0.318 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.682 0.318 0.000
I67.5 Moyamoya disease
0.682 0.318 0.000
I67.4 Hypertensive encephalopathy
0.682 0.318 0.000
I67.3 Progressive vascular leukoencephalopathy
0.682 0.318 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.682 0.318 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.682 0.318 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.682 0.318 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.682 0.318 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.682 0.318 0.000
D72 Other disorders of white blood cells
0.681 0.319 0.000
B25.9 Cytomegaloviral disease, unspecified
0.681 0.319 0.000
M77.1 Lateral epicondylitis
0.680 0.320 0.000
B44 Aspergillosis
0.680 0.320 0.000
A40.0 Septicaemia due to streptococcus, group A
0.680 0.320 0.000
E53 Deficiency of other B group vitamins
0.679 0.321 0.000
B99 Other and unspecified infectious diseases
0.679 0.321 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.679 0.321 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.679 0.321 0.000
G62.8 Other specified polyneuropathies
0.679 0.321 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.678 0.322 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.678 0.322 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.678 0.322 0.000
Z50.0 Cardiac rehabilitation
0.678 0.322 0.000
I30 Acute pericarditis
0.678 0.322 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.677 0.323 0.000
G90-G99 Other disorders of the nervous system
0.676 0.324 0.000
I36 Nonrheumatic tricuspid valve disorders
0.676 0.324 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.675 0.325 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.674 0.325 0.000
Z54 Convalescence
0.674 0.326 0.000
Z43 Attention to artificial openings
0.674 0.326 0.000
C07 Malignant neoplasm of parotid gland
0.673 0.327 0.000
I73.8 Other specified peripheral vascular diseases
0.673 0.327 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.673 0.327 0.000
G41 Status epilepticus
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
G43 Migraine
0.670 0.330 0.000
E40-E46 Malnutrition
0.670 0.330 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.669 0.331 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.669 0.331 0.000
C31 Malignant neoplasm of accessory sinuses
0.669 0.331 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.669 0.331 0.000
C37 Malignant neoplasm of thymus
0.669 0.331 0.000
C33 Malignant neoplasm of trachea
0.669 0.331 0.000
I51.4 Myocarditis, unspecified
0.669 0.331 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.668 0.332 0.000
Z51.2 Other chemotherapy
0.668 0.332 0.000
I42.9 Cardiomyopathy, unspecified
0.668 0.332 0.000
Q80-Q89 Other congenital malformations
0.668 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.667 0.333 0.000
Z46 Fitting and adjustment of other devices
0.666 0.334 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.666 0.334 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.666 0.334 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.666 0.334 0.000
I65.1 Occlusion and stenosis of basilar artery
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.666 0.334 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.664 0.336 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.662 0.338 0.000
C90.0 Multiple myeloma
0.661 0.339 0.000
B37.0 Candidal stomatitis
0.661 0.339 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.660 0.340 0.000
C92.1 Chronic myeloid leukaemia
0.660 0.340 0.000
D67 Hereditary factor IX deficiency
0.660 0.340 0.000
D66 Hereditary factor VIII deficiency
0.660 0.340 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.660 0.340 0.000
G44 Other headache syndromes
0.659 0.341 0.000
A49 Bacterial infection of unspecified site
0.659 0.341 0.000
B02 Zoster [herpes zoster]
0.658 0.342 0.000
B49 Unspecified mycosis
0.658 0.342 0.000
M20-M25 Other joint disorders
0.658 0.342 0.000
M43 Other deforming dorsopathies
0.658 0.342 0.000
D62 Acute posthaemorrhagic anaemia
0.657 0.343 0.000
D41.0 Kidney
0.657 0.343 0.000
I51.6 Cardiovascular disease, unspecified
0.656 0.344 0.000
I51.5 Myocardial degeneration
0.656 0.344 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.656 0.344 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.656 0.344 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.656 0.344 0.000
I51.0 Cardiac septal defect, acquired
0.656 0.344 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.656 0.344 0.000
M93 Other osteochondropathies
0.655 0.345 0.000
C13 Malignant neoplasm of hypopharynx
0.655 0.345 0.000
C11 Malignant neoplasm of nasopharynx
0.655 0.345 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.655 0.345 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.655 0.345 0.000
C03 Malignant neoplasm of gum
0.655 0.345 0.000
C00 Malignant neoplasm of lip
0.655 0.345 0.000
C12 Malignant neoplasm of pyriform sinus
0.655 0.345 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.655 0.345 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.655 0.345 0.000
Z49.2 Other dialysis
0.654 0.346 0.000
D53 Other nutritional anaemias
0.654 0.346 0.000
D68.9 Coagulation defect, unspecified
0.654 0.346 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.653 0.346 0.000
C92.0 Acute myeloid leukaemia
0.653 0.347 0.000
G60 Hereditary and idiopathic neuropathy
0.652 0.348 0.000
B00 Herpesviral [herpes simplex] infections
0.650 0.350 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.650 0.350 0.000
H92 Otalgia and effusion of ear
0.650 0.350 0.000
I44.7 Left bundle-branch block, unspecified
0.650 0.350 0.000
C51 Malignant neoplasm of vulva
0.648 0.351 0.000
Z76 Persons encountering health services in other circumstances
0.648 0.352 0.000
M10.99 Gout, unspecified (Site unspecified)
0.648 0.352 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.647 0.353 0.000
Z50.1 Other physical therapy
0.647 0.353 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.647 0.353 0.000
C58 Malignant neoplasm of placenta
0.647 0.353 0.000
C52 Malignant neoplasm of vagina
0.647 0.353 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.646 0.354 0.000
E32 Diseases of thymus
0.646 0.354 0.000
E31 Polyglandular dysfunction
0.646 0.354 0.000
E30 Disorders of puberty, not elsewhere classified
0.646 0.354 0.000
E26 Hyperaldosteronism
0.646 0.354 0.000
E25 Adrenogenital disorders
0.646 0.354 0.000
E24 Cushing's syndrome
0.646 0.354 0.000
E20 Hypoparathyroidism
0.646 0.354 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.646 0.354 0.000
J95-J99 Other diseases of the respiratory system
0.645 0.355 0.000
B33 Other viral diseases, not elsewhere classified
0.642 0.358 0.000
B30 Viral conjunctivitis
0.642 0.358 0.000
B27 Infectious mononucleosis
0.642 0.358 0.000
B26 Mumps
0.642 0.358 0.000
C71 Malignant neoplasm of brain
0.641 0.359 0.000
Z50.6 Orthoptic training
0.640 0.360 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.640 0.360 0.000
Z50.3 Drug rehabilitation
0.640 0.360 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.639 0.361 0.000
Z28 Immunisation not carried out
0.638 0.362 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.638 0.362 0.000
Z26 Need for immunisation against other single infectious diseases
0.638 0.362 0.000
Z25 Need for immunisation against other single viral diseases
0.638 0.362 0.000
Z24 Need for immunisation against certain single viral diseases
0.638 0.362 0.000
Z23 Need for immunisation against single bacterial diseases
0.638 0.362 0.000
Z20 Contact with and exposure to communicable diseases
0.638 0.362 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.638 0.362 0.000
I99 Other and unspecified disorders of circulatory system
0.638 0.362 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.638 0.362 0.000
B48 Other mycoses, not elsewhere classified
0.636 0.364 0.000
B47 Mycetoma
0.636 0.364 0.000
B46 Zygomycosis
0.636 0.364 0.000
B45 Cryptococcosis
0.636 0.364 0.000
B43 Chromomycosis and phaeomycotic abscess
0.636 0.364 0.000
B42 Sporotrichosis
0.636 0.364 0.000
B41 Paracoccidioidomycosis
0.636 0.364 0.000
B40 Blastomycosis
0.636 0.364 0.000
B39 Histoplasmosis
0.636 0.364 0.000
B38 Coccidioidomycosis
0.636 0.364 0.000
B36 Other superficial mycoses
0.636 0.364 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.633 0.366 0.000
E28 Ovarian dysfunction
0.633 0.367 0.000
J18 Pneumonia, organism unspecified
0.632 0.368 0.000
E14 Unspecified diabetes mellitus
0.632 0.368 0.000
J40-J47 Chronic lower respiratory diseases
0.631 0.369 0.000
D61 Other aplastic anaemias
0.630 0.369 0.000
D47.2 Monoclonal gammopathy
0.630 0.370 0.000
E65-E68 Obesity and other hyperalimentation
0.630 0.370 0.000
C32.0 Glottis
0.629 0.371 0.000
D46 Myelodysplastic syndromes
0.629 0.371 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.628 0.371 0.000
M77.9 Enthesopathy, unspecified
0.628 0.372 0.000
B37.3 Candidiasis of vulva and vagina
0.628 0.372 0.000
Q00-Q07 Congenital malformations of the nervous system
0.628 0.372 0.000
I07 Rheumatic tricuspid valve diseases
0.627 0.373 0.000
E61 Deficiency of other nutrient elements
0.627 0.373 0.000
C14.0 Pharynx, unspecified
0.627 0.373 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.627 0.373 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.625 0.375 0.000
M11 Other crystal arthropathies
0.624 0.375 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.624 0.376 0.000
J84 Other interstitial pulmonary diseases
0.623 0.377 0.000
V40-V49 Car occupant injured in transport accident
0.623 0.377 0.000
G61 Inflammatory polyneuropathy
0.622 0.378 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.622 0.378 0.000
C95 Leukaemia of unspecified cell type
0.622 0.378 0.000
C94 Other leukaemias of specified cell type
0.622 0.378 0.000
C93 Monocytic leukaemia
0.622 0.378 0.000
C88 Malignant immunoproliferative diseases
0.622 0.378 0.000
C86 Other specified types of T/NK-cell lymphoma
0.622 0.378 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.622 0.378 0.000
M10.96 Gout, unspecified (Lower leg)
0.621 0.379 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.621 0.379 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.621 0.379 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.621 0.379 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.620 0.380 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.619 0.380 0.000
I78 Diseases of capillaries
0.619 0.381 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.618 0.381 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.618 0.381 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.618 0.381 0.000
I67.9 Cerebrovascular disease, unspecified
0.618 0.382 0.000
D75 Other diseases of blood and blood-forming organs
0.618 0.382 0.000
M06 Other rheumatoid arthritis
0.618 0.382 0.000
C09 Malignant neoplasm of tonsil
0.617 0.383 0.000
C32.8 Overlapping lesion of larynx
0.617 0.383 0.000
C32.3 Laryngeal cartilage
0.617 0.383 0.000
C32.2 Subglottis
0.617 0.383 0.000
B01 Varicella [chickenpox]
0.616 0.383 0.000
G64 Other disorders of peripheral nervous system
0.615 0.385 0.000
Z36 Antenatal screening
0.615 0.385 0.000
A40.9 Streptococcal septicaemia, unspecified
0.615 0.385 0.000
A40.2 Septicaemia due to streptococcus, group D
0.615 0.385 0.000
A40.1 Septicaemia due to streptococcus, group B
0.615 0.385 0.000
M14 Arthropathies in other diseases classified elsewhere
0.614 0.386 0.000
M12 Other specific arthropathies
0.614 0.386 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.614 0.386 0.000
M08 Juvenile arthritis
0.614 0.386 0.000
M13.9 Arthritis, unspecified
0.614 0.386 0.000
E27.8 Other specified disorders of adrenal gland
0.613 0.387 0.000
W20-W49 Exposure to inanimate mechanical forces
0.613 0.387 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.612 0.387 0.000
I74.8 Embolism and thrombosis of other arteries
0.612 0.387 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.612 0.387 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.612 0.387 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.612 0.387 0.000
I27 Other pulmonary heart diseases
0.613 0.387 0.000
C81 Hodgkin's disease
0.612 0.388 0.000
Z63 Other problems related to primary support group, including family circumstances
0.612 0.388 0.000
B34.9 Viral infection, unspecified
0.611 0.389 0.000
H90.5 Sensorineural hearing loss, unspecified
0.610 0.390 0.000
Z45.8 Adjustment and management of other implanted devices
0.610 0.390 0.000
E34.8 Other specified endocrine disorders
0.609 0.390 0.000
G20 Parkinson's disease
0.608 0.392 0.000
M62 Other disorders of muscle
0.608 0.392 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.608 0.392 0.000
E23.2 Diabetes insipidus
0.607 0.393 0.000
I34.0 Mitral (valve) insufficiency
0.607 0.393 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.607 0.393 0.000
Z43.1 Attention to gastrostomy
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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