TreeWAS – Variant ID: rs7499271

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z88.0 Personal history of allergy to penicillin	0.000	0.957	0.043
S82.80 Fractures of other parts of lower leg (closed)	0.008	0.992	0.000
S82.8 Fractures of other parts of lower leg	0.005	0.994	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.005	0.995	0.000
S82.86 Maisonneuve's fracture	0.004	0.996	0.000
S82.81 Fractures of other parts of lower leg (open)	0.004	0.996	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.996	0.004
S82 Fracture of lower leg, including ankle	0.004	0.996	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.004	0.996	0.000
S82.6 Fracture of lateral malleolus	0.003	0.996	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.000	0.997	0.003
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
S82.1 Fracture of upper end of tibia	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.003	0.997	0.000
S82.9 Fracture of lower leg, part unspecified	0.003	0.997	0.000
S82.7 Multiple fractures of lower leg	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.997	0.003
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.003	0.997	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.003	0.997	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.003	0.997	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.003	0.997	0.000
S82.4 Fracture of fibula alone	0.003	0.997	0.000
S82.10 Fracture of upper end of tibia (closed)	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.997	0.000
K92.0 Haematemesis	0.000	0.997	0.003
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.002	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.997	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.997	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.997	0.000
H53 Visual disturbances	0.003	0.997	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.002	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.998	0.002
H53.8 Other visual disturbances	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.000	0.998	0.002
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
S80.0 Contusion of knee	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.998	0.002
S89 Other and unspecified injuries of lower leg	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
I95.9 Hypotension, unspecified	0.000	0.998	0.002
H53.6 Night blindness	0.002	0.998	0.000
H53.5 Colour vision deficiencies	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
H53.3 Other disorders of binocular vision	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.998	0.002
J33 Nasal polyp	0.000	0.998	0.002
H53.0 Amblyopia ex anopsia	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.000	0.998	0.002
D50 Iron deficiency anaemia	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
S62.6 Fracture of other finger	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
G47.3 Sleep apnoea	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
F41 Other anxiety disorders	0.000	0.998	0.002
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
Y43 Primarily systemic agents	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.000	0.998	0.002
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
D50.1 Sideropenic dysphagia	0.000	0.998	0.001
J33.1 Polypoid sinus degeneration	0.000	0.998	0.002
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.998	0.002
S62.0 Fracture of navicular [scaphoid] bone of hand	0.001	0.998	0.000
G62 Other polyneuropathies	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.001	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.998	0.000
S69 Other and unspecified injuries of wrist and hand	0.001	0.998	0.000
S67 Crushing injury of wrist and hand	0.001	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.001	0.998	0.000
S01.0 Open wound of scalp	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.001	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.001	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.001	0.998	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.001	0.998	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.001	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.001	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.001	0.998	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.001	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.001	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.998	0.000
S62.7 Multiple fractures of fingers	0.001	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.001	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.001	0.998	0.000
S63.1 Dislocation finger	0.001	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.001	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.001	0.998	0.000
S63.5 Sprain and strain of wrist	0.001	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.001	0.998	0.000
S63.2 Multiple dislocations of fingers	0.001	0.998	0.000
S63.0 Dislocation of wrist	0.001	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.998	0.000
S06.3 Focal brain injury	0.001	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.001	0.998	0.000
S81.0 Open wound of knee	0.001	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.998	0.001
S06.8 Other intracranial injuries	0.001	0.998	0.000
S83.7 Injury to multiple structures of knee	0.001	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.001	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.001	0.998	0.000
S83.1 Dislocation of knee	0.001	0.998	0.000
S83.0 Dislocation of patella	0.001	0.998	0.000
N62 Hypertrophy of breast	0.000	0.998	0.002
F41.8 Other specified anxiety disorders	0.000	0.998	0.001
F41.3 Other mixed anxiety disorders	0.000	0.998	0.001
S01.7 Multiple open wounds of head	0.001	0.998	0.000
S62.5 Fracture of thumb	0.001	0.998	0.000
S01 Open wound of head	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.001	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.998	0.000
C15.9 Oesophagus, unspecified	0.001	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.001	0.998	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.001	0.998	0.000
S60.2 Contusion of other parts of wrist and hand	0.001	0.998	0.000
S60.1 Contusion of finger(s) with damage to nail	0.001	0.998	0.000
S60.0 Contusion of finger(s) without damage to nail	0.001	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.001	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.001	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.001	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.001	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.001	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
M19.0 Primary arthrosis of other joints	0.001	0.998	0.000
O14.2 HELLP syndrome	0.001	0.998	0.000
O14.1 Severe preeclampsia	0.001	0.998	0.000
O14.0 Moderate preeclampsia	0.001	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.001	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.998	0.000
S27.6 Injury of pleura	0.001	0.998	0.000
S27.5 Injury of thoracic trachea	0.001	0.998	0.000
S27.4 Injury of bronchus	0.001	0.998	0.000
S27.3 Other injuries of lung	0.001	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.998	0.000
S27.1 Traumatic haemothorax	0.001	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.001	0.998	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.001	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.001	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.001	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.001	0.998	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.001	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.001	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.000	0.998	0.001
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.998	0.001
Y43.6 Enzymes, not elsewhere classified	0.000	0.998	0.001
Y43.5 Acidifying and alkalising agents	0.000	0.998	0.001
Y43.4 Immunosuppressive agents	0.000	0.998	0.001
Y43.2 Antineoplastic natural products	0.000	0.998	0.001
Y43.0 Antiallergic and antiemetic drugs	0.000	0.998	0.001
S90-S99 Injuries to the ankle and foot	0.001	0.998	0.000
S00-S09 Injuries to the head	0.001	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.001	0.999	0.000
O15 Eclampsia	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q26 Congenital malformations of great veins	0.001	0.999	0.000
Q25 Congenital malformations of great arteries	0.001	0.999	0.000
Q24 Other congenital malformations of heart	0.001	0.999	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.001	0.999	0.000
S02 Fracture of skull and facial bones	0.001	0.999	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.999	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.999	0.001
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.999	0.001
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.999	0.001
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.999	0.001
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.001	0.999	0.001
G62.2 Polyneuropathy due to other toxic agents	0.001	0.999	0.000
G62.1 Alcoholic polyneuropathy	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.001	0.999	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.999	0.001
S10-S19 Injuries to the neck	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
F10.3 Withdrawal state	0.000	0.999	0.001
F41.1 Generalised anxiety disorder	0.000	0.999	0.001
S02.6 Fracture of mandible	0.001	0.999	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.001	0.999	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.001	0.999	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.001	0.999	0.000
S65.5 Injury of blood vessel(s) of other finger	0.001	0.999	0.000
S65.4 Injury of blood vessel(s) of thumb	0.001	0.999	0.000
S65.3 Injury of deep palmar arch	0.001	0.999	0.000
S65.2 Injury of superficial palmar arch	0.001	0.999	0.000
S65.1 Injury of radial artery at wrist and hand level	0.001	0.999	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.001	0.999	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.001	0.999	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.001	0.999	0.000
S69.9 Unspecified injury of wrist and hand	0.001	0.999	0.000
S69.8 Other specified injuries of wrist and hand	0.001	0.999	0.000
S69.7 Multiple injuries of wrist and hand	0.001	0.999	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.001	0.999	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
G61.1 Serum neuropathy	0.001	0.999	0.000
S64.4 Injury of digital nerve of other finger	0.001	0.999	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.001	0.999	0.000
S26 Injury of heart	0.001	0.999	0.000
S25 Injury of blood vessels of thorax	0.001	0.999	0.000
S24 Injury of nerves and spinal cord at thorax level	0.001	0.999	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.001	0.999	0.000
S21 Open wound of thorax	0.001	0.999	0.000
S51 Open wound of forearm	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
T18 Foreign body in alimentary tract	0.001	0.999	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.999	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.001	0.999	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.999	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.999	0.001
F41.2 Mixed anxiety and depressive disorder	0.000	0.999	0.001
N18.9 Chronic renal failure, unspecified	0.001	0.999	0.000
S06.9 Intracranial injury, unspecified	0.001	0.999	0.000
S06.7 Intracranial injury with prolonged coma	0.001	0.999	0.000
S06.4 Epidural haemorrhage	0.001	0.999	0.000
S06.1 Traumatic cerebral oedema	0.001	0.999	0.000
S06.0 Concussion	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
S50-S59 Injuries to the elbow and forearm	0.001	0.999	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.999	0.001
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.999	0.000
S06.2 Diffuse brain injury	0.001	0.999	0.000
S51.9 Open wound of forearm, part unspecified	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
T79-T79 Certain early complications of trauma	0.001	0.999	0.000
T33-T35 Frostbite	0.001	0.999	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.999	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999	0.000
T00-T07 Injuries involving multiple body regions	0.001	0.999	0.000
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
C15.5 Lower third of oesophagus	0.001	0.999	0.000
N99.0 Postprocedural renal failure	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
S01.4 Open wound of cheek and temporomandibular area	0.001	0.999	0.000
S06.5 Traumatic subdural haemorrhage	0.001	0.999	0.000
S29.8 Other specified injuries of thorax	0.001	0.999	0.000
S29.7 Multiple injuries of thorax	0.001	0.999	0.000
S29.0 Injury of muscle and tendon at thorax level	0.001	0.999	0.000
T18.1 Foreign body in oesophagus	0.001	0.999	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.999	0.001
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.001	0.999	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999	0.000
L73.2 Hidradenitis suppurativa	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
S02.1 Fracture of base of skull	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.999	0.000
T17 Foreign body in respiratory tract	0.001	0.999	0.000
M19.08 Primary arthrosis of other joints (Other)	0.001	0.999	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.001	0.999	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.001	0.999	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.001	0.999	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.999	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
O12.1 Gestational proteinuria	0.001	0.999	0.000
O12.0 Gestational oedema	0.001	0.999	0.000
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.1 Congenital pulmonary valve stenosis	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
Q24.6 Congenital heart block	0.001	0.999	0.000
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Q24.0 Dextrocardia	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q25.1 Coarctation of aorta	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.999	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.999	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.999	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.000
S01.8 Open wound of other parts of head	0.001	0.999	0.000
S02.2 Fracture of nasal bones	0.001	0.999	0.000
S51.0 Open wound of elbow	0.001	0.999	0.000
S08 Traumatic amputation of part of head	0.001	0.999	0.000
S07 Crushing injury of head	0.001	0.999	0.000
S05 Injury of eye and orbit	0.001	0.999	0.000
S04 Injury of cranial nerves	0.001	0.999	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.001	0.999	0.000
S19 Other and unspecified injuries of neck	0.001	0.999	0.000
S20 Superficial injury of thorax	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
S90 Superficial injury of ankle and foot	0.001	0.999	0.000
T19 Foreign body in genito-urinary tract	0.001	0.999	0.000
T15 Foreign body on external eye	0.001	0.999	0.000
T16 Foreign body in ear	0.001	0.999	0.000
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.999	0.001
C79.6 Secondary malignant neoplasm of ovary	0.000	0.999	0.001
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations