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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11867071
log Bayes Factor = 14.7556
Chromosome 16   position 68,760,442  (GRCh37) Explore rs11867071 on Ensembl!
Variant rs11867071 is part of Cluster X0229

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20 Angina pectoris
0.997 0.003 0.000
I20.9 Angina pectoris, unspecified
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
Chapter II Neoplasms
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
I44 Atrioventricular and left bundle-branch block
0.992 0.008 0.000
J30-J39 Other diseases of upper respiratory tract
0.988 0.012 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.980 0.020 0.000
F30-F39 Mood [affective] disorders
0.978 0.022 0.000
Chapter I Certain infectious and parasitic diseases
0.973 0.027 0.000
I50 Heart failure
0.972 0.028 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.967 0.033 0.000
D00-D09 In situ neoplasms
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.959 0.041 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.956 0.044 0.000
I44.7 Left bundle-branch block, unspecified
0.955 0.045 0.000
B95-B98 Bacterial, viral and other infectious agents
0.952 0.048 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.948 0.052 0.000
I44.0 Atrioventricular block, first degree
0.946 0.054 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.942 0.058 0.000
S00-S09 Injuries to the head
0.938 0.062 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
I50.9 Heart failure, unspecified
0.938 0.062 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.937 0.063 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.935 0.065 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.934 0.066 0.000
Chapter XI Diseases of the digestive system
0.933 0.067 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.932 0.068 0.000
E00-E07 Disorders of thyroid gland
0.928 0.072 0.000
C34 Malignant neoplasm of bronchus and lung
0.928 0.072 0.000
Y83.8 Other surgical procedures
0.926 0.074 0.000
I10-I15 Hypertensive diseases
0.923 0.077 0.000
Chapter VI Diseases of the nervous system
0.921 0.079 0.000
F32 Depressive episode
0.913 0.087 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.912 0.088 0.000
I12 Hypertensive renal disease
0.908 0.092 0.000
F33 Recurrent depressive disorder
0.905 0.095 0.000
J09-J18 Influenza and pneumonia
0.901 0.099 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.897 0.103 0.000
T93 Sequelae of injuries of lower limb
0.897 0.103 0.000
J90-J94 Other diseases of pleura
0.896 0.104 0.000
I12.0 Hypertensive renal disease with renal failure
0.895 0.105 0.000
I25 Chronic ischaemic heart disease
0.890 0.110 0.000
E20-E35 Disorders of other endocrine glands
0.889 0.111 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.884 0.116 0.000
L03 Cellulitis
0.881 0.119 0.000
E03 Other hypothyroidism
0.877 0.123 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.876 0.124 0.000
S40-S49 Injuries to the shoulder and upper arm
0.873 0.127 0.000
T81 Complications of procedures, not elsewhere classified
0.867 0.133 0.000
C34.9 Bronchus or lung, unspecified
0.866 0.134 0.000
I35 Nonrheumatic aortic valve disorders
0.865 0.135 0.000
S02 Fracture of skull and facial bones
0.864 0.136 0.000
T93.2 Sequelae of other fractures of lower limb
0.861 0.139 0.000
I44.2 Atrioventricular block, complete
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.857 0.143 0.000
D68 Other coagulation defects
0.857 0.143 0.000
I50.1 Left ventricular failure
0.856 0.144 0.000
Chapter VII Diseases of the eye and adnexa
0.854 0.146 0.000
D04 Carcinoma in situ of skin
0.853 0.147 0.000
I21 Acute myocardial infarction
0.852 0.148 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.849 0.151 0.000
C15-C26 Malignant neoplasms of digestive organs
0.849 0.151 0.000
J34 Other disorders of nose and nasal sinuses
0.849 0.151 0.000
S60-S69 Injuries to the wrist and hand
0.848 0.152 0.000
J37 Chronic laryngitis and laryngotracheitis
0.848 0.152 0.000
J33 Nasal polyp
0.848 0.152 0.000
G40-G47 Episodic and paroxysmal disorders
0.846 0.154 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.845 0.155 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.844 0.156 0.000
E03.9 Hypothyroidism, unspecified
0.841 0.159 0.000
C64-C68 Malignant neoplasms of urinary tract
0.838 0.162 0.000
I22 Subsequent myocardial infarction
0.836 0.164 0.000
Y83.0 Surgical operation with transplant of whole organ
0.832 0.167 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.832 0.168 0.000
C18 Malignant neoplasm of colon
0.832 0.168 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
G43 Migraine
0.831 0.169 0.000
L03.1 Cellulitis of other parts of limb
0.826 0.174 0.000
D06 Carcinoma in situ of cervix uteri
0.824 0.176 0.000
G43.9 Migraine, unspecified
0.820 0.180 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.818 0.182 0.000
J18 Pneumonia, organism unspecified
0.817 0.183 0.000
W00-W19 Falls
0.815 0.185 0.000
J38.7 Other diseases of larynx
0.813 0.187 0.000
I20.1 Angina pectoris with documented spasm
0.812 0.188 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.807 0.193 0.000
F60-F69 Disorders of adult personality and behaviour
0.807 0.193 0.000
I05-I09 Chronic rheumatic heart diseases
0.802 0.198 0.000
Y83.4 Other reconstructive surgery
0.802 0.198 0.000
J35 Chronic diseases of tonsils and adenoids
0.802 0.198 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.802 0.198 0.000
K14 Diseases of tongue
0.797 0.203 0.000
F33.9 Recurrent depressive disorder, unspecified
0.797 0.203 0.000
S00 Superficial injury of head
0.797 0.203 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.795 0.205 0.000
C18.7 Sigmoid colon
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
S42 Fracture of shoulder and upper arm
0.793 0.207 0.000
J32 Chronic sinusitis
0.791 0.209 0.000
B35-B49 Mycoses
0.789 0.211 0.000
J38.3 Other diseases of vocal cords
0.787 0.213 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.787 0.213 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.787 0.213 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.785 0.215 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.784 0.216 0.000
J93 Pneumothorax
0.783 0.217 0.000
L20-L30 Dermatitis and eczema
0.783 0.217 0.000
I20.8 Other forms of angina pectoris
0.782 0.218 0.000
F32.9 Depressive episode, unspecified
0.781 0.219 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.780 0.220 0.000
C34.1 Upper lobe, bronchus or lung
0.779 0.221 0.000
D05 Carcinoma in situ of breast
0.778 0.222 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.777 0.223 0.000
F31 Bipolar affective disorder
0.776 0.224 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.775 0.225 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.772 0.228 0.000
J38.0 Paralysis of vocal cords and larynx
0.770 0.230 0.000
I21.9 Acute myocardial infarction, unspecified
0.769 0.231 0.000
S80-S89 Injuries to the knee and lower leg
0.768 0.232 0.000
I36 Nonrheumatic tricuspid valve disorders
0.767 0.233 0.000
T86 Failure and rejection of transplanted organs and tissues
0.767 0.233 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.765 0.235 0.000
I44.3 Other and unspecified atrioventricular block
0.764 0.236 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.763 0.237 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.763 0.237 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.763 0.237 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.762 0.238 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.761 0.239 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.760 0.240 0.000
C34.3 Lower lobe, bronchus or lung
0.759 0.241 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.757 0.243 0.000
E27 Other disorders of adrenal gland
0.757 0.243 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.756 0.244 0.000
S01 Open wound of head
0.755 0.244 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.755 0.245 0.000
I35.0 Aortic (valve) stenosis
0.755 0.245 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.755 0.245 0.000
B02 Zoster [herpes zoster]
0.753 0.247 0.000
T90 Sequelae of injuries of head
0.753 0.247 0.000
I44.1 Atrioventricular block, second degree
0.753 0.247 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.752 0.248 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
D69 Purpura and other haemorrhagic conditions
0.750 0.250 0.000
I25.5 Ischaemic cardiomyopathy
0.749 0.251 0.000
D04.6 Skin of upper limb, including shoulder
0.749 0.251 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.748 0.252 0.000
S42.2 Fracture of upper end of humerus
0.748 0.252 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.748 0.252 0.000
J37.0 Chronic laryngitis
0.747 0.253 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.746 0.254 0.000
Chapter XXII Codes for special purposes
0.746 0.254 0.000
S02.4 Fracture of malar and maxillary bones
0.745 0.255 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.744 0.256 0.000
C67 Malignant neoplasm of bladder
0.742 0.258 0.000
C18.0 Caecum
0.742 0.258 0.000
C32 Malignant neoplasm of larynx
0.742 0.258 0.000
K40-K46 Hernia
0.740 0.260 0.000
S70-S79 Injuries to the hip and thigh
0.739 0.261 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.737 0.263 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.735 0.265 0.000
D68.8 Other specified coagulation defects
0.735 0.265 0.000
J33.8 Other polyp of sinus
0.734 0.265 0.000
I49 Other cardiac arrhythmias
0.734 0.266 0.000
Chapter XIV Diseases of the genitourinary system
0.734 0.266 0.000
E07 Other disorders of thyroid
0.733 0.267 0.000
K35-K38 Diseases of appendix
0.733 0.267 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.733 0.267 0.000
J90 Pleural effusion, not elsewhere classified
0.733 0.267 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.732 0.268 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.731 0.269 0.000
S20-S29 Injuries to the thorax
0.731 0.269 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.730 0.270 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.729 0.271 0.000
S61 Open wound of wrist and hand
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
L03.8 Cellulitis of other sites
0.728 0.272 0.000
D50-D53 Nutritional anaemias
0.727 0.273 0.000
D10-D36 Benign neoplasms
0.726 0.274 0.000
K82 Other diseases of gallbladder
0.726 0.274 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.726 0.274 0.000
D06.9 Cervix, unspecified
0.725 0.275 0.000
D03 Melanoma in situ
0.725 0.275 0.000
F00 Dementia in Alzheimer's disease
0.725 0.275 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.723 0.277 0.000
T66-T78 Other and unspecified effects of external causes
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
E22 Hyperfunction of pituitary gland
0.722 0.278 0.000
K70-K77 Diseases of liver
0.722 0.278 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
E06 Thyroiditis
0.721 0.279 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.720 0.280 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.719 0.280 0.000
K81 Cholecystitis
0.719 0.281 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
F32.1 Moderate depressive episode
0.719 0.281 0.000
G30-G32 Other degenerative diseases of the nervous system
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
J39 Other diseases of upper respiratory tract
0.716 0.284 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.716 0.284 0.000
S42.20 Fracture of upper end of humerus (closed)
0.715 0.285 0.000
W20-W49 Exposure to inanimate mechanical forces
0.714 0.286 0.000
S00.8 Superficial injury of other parts of head
0.714 0.286 0.000
L03.9 Cellulitis, unspecified
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
Y00-Y09 Assault
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.286 0.000
X10-X19 Contact with heat and hot substances
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V80-V89 Other land transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.286 0.000
F80-F89 Disorders of psychological development
0.713 0.286 0.000
F70-F79 Mental retardation
0.713 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
L40-L45 Papulosquamous disorders
0.713 0.287 0.000
S02.2 Fracture of nasal bones
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I33 Acute and subacute endocarditis
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
D09 Carcinoma in situ of other and unspecified sites
0.712 0.288 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.712 0.288 0.000
K85 Acute pancreatitis
0.712 0.288 0.000
J10 Influenza due to identified influenza virus
0.711 0.289 0.000
F03 Unspecified dementia
0.711 0.289 0.000
I24 Other acute ischaemic heart diseases
0.711 0.289 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.711 0.289 0.000
L08 Other local infections of skin and subcutaneous tissue
0.711 0.289 0.000
I44.6 Other and unspecified fascicular block
0.711 0.289 0.000
I44.5 Left posterior fascicular block
0.711 0.289 0.000
I44.4 Left anterior fascicular block
0.711 0.289 0.000
K83 Other diseases of biliary tract
0.711 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.710 0.290 0.000
H25-H28 Disorders of lens
0.710 0.290 0.000
C51-C58 Malignant neoplasms of female genital organs
0.708 0.292 0.000
G20-G26 Extrapyramidal and movement disorders
0.707 0.293 0.000
C18.9 Colon, unspecified
0.706 0.294 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.705 0.295 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.705 0.295 0.000
J18.0 Bronchopneumonia, unspecified
0.704 0.296 0.000
J00-J06 Acute upper respiratory infections
0.704 0.296 0.000
F32.0 Mild depressive episode
0.703 0.296 0.000
H40-H42 Glaucoma
0.703 0.297 0.000
K04 Diseases of pulp and periapical tissues
0.703 0.297 0.000
K12 Stomatitis and related lesions
0.702 0.298 0.000
L03.2 Cellulitis of face
0.702 0.298 0.000
K43 Ventral hernia
0.702 0.298 0.000
F38 Other mood [affective] disorders
0.701 0.299 0.000
F34 Persistent mood [affective] disorders
0.701 0.299 0.000
F30 Manic episode
0.701 0.299 0.000
F39 Unspecified mood [affective] disorder
0.701 0.299 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.701 0.299 0.000
J38.1 Polyp of vocal cord and larynx
0.700 0.300 0.000
D68.5 Primary Thrombophilia
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.698 0.302 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.302 0.000
B65-B83 Helminthiases
0.698 0.302 0.000
B50-B64 Protozoal diseases
0.698 0.302 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.302 0.000
A80-A89 Viral infections of the central nervous system
0.698 0.302 0.000
A75-A79 Rickettsioses
0.698 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.302 0.000
A65-A69 Other spirochaetal diseases
0.698 0.302 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.698 0.302 0.000
J93.9 Pneumothorax, unspecified
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.695 0.305 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.695 0.305 0.000
I46 Cardiac arrest
0.694 0.306 0.000
Y83.5 Amputation of limb(s)
0.693 0.307 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.691 0.309 0.000
J95-J99 Other diseases of the respiratory system
0.691 0.309 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.690 0.310 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.690 0.310 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.690 0.310 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.689 0.311 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.689 0.311 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
K05 Gingivitis and periodontal diseases
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.688 0.312 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.688 0.312 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.688 0.312 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.688 0.312 0.000
C31 Malignant neoplasm of accessory sinuses
0.688 0.312 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.688 0.312 0.000
C37 Malignant neoplasm of thymus
0.688 0.312 0.000
C33 Malignant neoplasm of trachea
0.688 0.312 0.000
L30 Other dermatitis
0.688 0.312 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.686 0.314 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.686 0.314 0.000
L10-L14 Bullous disorders
0.685 0.314 0.000
J18.9 Pneumonia, unspecified
0.686 0.314 0.000
E29 Testicular dysfunction
0.685 0.315 0.000
K14.9 Disease of tongue, unspecified
0.684 0.316 0.000
I45 Other conduction disorders
0.684 0.316 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.682 0.317 0.000
J91 Pleural effusion in conditions classified elsewhere
0.681 0.319 0.000
F01 Vascular dementia
0.681 0.319 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.319 0.000
Y44 Agents primarily affecting blood constituents
0.681 0.319 0.000
C67.9 Bladder, unspecified
0.680 0.320 0.000
T98 Sequelae of other and unspecified effects of external causes
0.680 0.320 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.680 0.320 0.000
T92 Sequelae of injuries of upper limb
0.680 0.320 0.000
T91 Sequelae of injuries of neck and trunk
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
S68 Traumatic amputation of wrist and hand
0.679 0.321 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.321 0.000
D60-D64 Aplastic and other anaemias
0.679 0.321 0.000
I12.9 Hypertensive renal disease without renal failure
0.678 0.322 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.678 0.322 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.676 0.324 0.000
J33.9 Nasal polyp, unspecified
0.676 0.324 0.000
H55-H59 Other disorders of eye and adnexa
0.676 0.324 0.000
T87 Complications peculiar to reattachment and amputation
0.675 0.324 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.675 0.324 0.000
I08 Multiple valve diseases
0.675 0.325 0.000
I50.0 Congestive heart failure
0.675 0.325 0.000
E70-E90 Metabolic disorders
0.675 0.325 0.000
S02.1 Fracture of base of skull
0.675 0.325 0.000
K00 Disorders of tooth development and eruption
0.674 0.325 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.674 0.326 0.000
S08 Traumatic amputation of part of head
0.673 0.327 0.000
S07 Crushing injury of head
0.673 0.327 0.000
S05 Injury of eye and orbit
0.673 0.327 0.000
S04 Injury of cranial nerves
0.673 0.327 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.673 0.327 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.673 0.327 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.673 0.327 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.673 0.327 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.673 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.327 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
T36 Poisoning by systemic antibiotics
0.673 0.327 0.000
D68.9 Coagulation defect, unspecified
0.672 0.328 0.000
D05.1 Intraductal carcinoma in situ
0.672 0.328 0.000
F60 Specific personality disorders
0.672 0.328 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.672 0.328 0.000
J38.6 Stenosis of larynx
0.671 0.329 0.000
J38.5 Laryngeal spasm
0.671 0.329 0.000
J38.4 Oedema of larynx
0.671 0.329 0.000
J38.2 Nodules of vocal cords
0.671 0.329 0.000
D04.5 Skin of trunk
0.670 0.329 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.670 0.330 0.000
L04 Acute lymphadenitis
0.670 0.330 0.000
L01 Impetigo
0.670 0.330 0.000
L00 Staphylococcal scalded skin syndrome
0.670 0.330 0.000
T14 Injury of unspecified body region
0.669 0.331 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.668 0.332 0.000
Y83.3 Surgical operation with formation of external stoma
0.667 0.332 0.000
B02.9 Zoster without complication
0.666 0.334 0.000
J36 Peritonsillar abscess
0.666 0.334 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.666 0.334 0.000
K13 Other diseases of lip and oral mucosa
0.666 0.334 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.665 0.335 0.000
E00 Congenital iodine-deficiency syndrome
0.665 0.335 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.335 0.000
C34.8 Overlapping lesion of bronchus and lung
0.665 0.335 0.000
C34.2 Middle lobe, bronchus or lung
0.665 0.335 0.000
C34.0 Main bronchus
0.665 0.335 0.000
K10 Other diseases of jaws
0.665 0.335 0.000
C25 Malignant neoplasm of pancreas
0.664 0.336 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.663 0.337 0.000
J60-J70 Lung diseases due to external agents
0.663 0.337 0.000
I15 Secondary hypertension
0.662 0.338 0.000
I13 Hypertensive heart and renal disease
0.662 0.338 0.000
I11 Hypertensive heart disease
0.662 0.338 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.660 0.340 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.660 0.340 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.660 0.340 0.000
K80 Cholelithiasis
0.658 0.342 0.000
J32.0 Chronic maxillary sinusitis
0.657 0.343 0.000
E23 Hypofunction and other disorders of pituitary gland
0.656 0.344 0.000
S06 Intracranial injury
0.655 0.345 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.655 0.345 0.000
F32.8 Other depressive episodes
0.655 0.345 0.000
L05 Pilonidal cyst
0.654 0.346 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
D67 Hereditary factor IX deficiency
0.654 0.346 0.000
D66 Hereditary factor VIII deficiency
0.654 0.346 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.654 0.346 0.000
K14.8 Other diseases of tongue
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.653 0.347 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.652 0.348 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.651 0.348 0.000
E27.1 Primary adrenocortical insufficiency
0.651 0.349 0.000
D12.5 Sigmoid colon
0.650 0.350 0.000
E50-E64 Other nutritional deficiencies
0.649 0.351 0.000
K01 Embedded and impacted teeth
0.649 0.351 0.000
F33.8 Other recurrent depressive disorders
0.648 0.351 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.648 0.351 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.648 0.351 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.648 0.351 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.648 0.351 0.000
D80-D89 Certain disorders involving the immune mechanism
0.648 0.352 0.000
S02.5 Fracture of tooth
0.647 0.353 0.000
L50-L54 Urticaria and erythema
0.647 0.353 0.000
D75 Other diseases of blood and blood-forming organs
0.647 0.353 0.000
J17 Pneumonia in diseases classified elsewhere
0.646 0.354 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.646 0.354 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.646 0.354 0.000
J12 Viral pneumonia, not elsewhere classified
0.646 0.354 0.000
J11 Influenza, virus not identified
0.646 0.354 0.000
J14 Pneumonia due to Haemophilus influenzae
0.646 0.354 0.000
J09 Influenza due to certain identified influenza virus
0.646 0.354 0.000
S60 Superficial injury of wrist and hand
0.645 0.355 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.645 0.355 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.644 0.356 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.643 0.357 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.643 0.357 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.643 0.357 0.000
F02 Dementia in other diseases classified elsewhere
0.643 0.357 0.000
F09 Unspecified organic or symptomatic mental disorder
0.643 0.357 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.643 0.357 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.643 0.357 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.643 0.357 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.643 0.357 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.643 0.357 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.643 0.357 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.643 0.357 0.000
T93.1 Sequelae of fracture of femur
0.643 0.357 0.000
T93.0 Sequelae of open wound of lower limb
0.643 0.357 0.000
N17-N19 Renal failure
0.643 0.357 0.000
T39.1 4-Aminophenol derivatives
0.643 0.357 0.000
J94 Other pleural conditions
0.642 0.358 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.642 0.358 0.000
K82.4 Cholesterolosis of gallbladder
0.641 0.359 0.000
T86.1 Kidney transplant failure and rejection
0.641 0.359 0.000
I35.9 Aortic valve disorder, unspecified
0.639 0.361 0.000
D05.0 Lobular carcinoma in situ
0.639 0.361 0.000
I25.6 Silent myocardial ischaemia
0.638 0.362 0.000
I25.4 Coronary artery aneurysm
0.638 0.362 0.000
I25.3 Aneurysm of heart
0.638 0.362 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.638 0.362 0.000
D72 Other disorders of white blood cells
0.638 0.362 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.637 0.363 0.000
E34 Other endocrine disorders
0.637 0.363 0.000
E32 Diseases of thymus
0.637 0.363 0.000
E31 Polyglandular dysfunction
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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