TreeWAS – Variant ID: rs16948255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.998	0.002
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.001	0.998	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.998	0.001
Z86.6 Personal history of diseases of the nervous system and sense organs	0.001	0.999	0.000
N40 Hyperplasia of prostate	0.001	0.999	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.001	0.999	0.000
Z86.7 Personal history of diseases of the circulatory system	0.001	0.999	0.000
Y83.6 Removal of other organ (partial) (total)	0.001	0.999	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.999	0.001
E78.8 Other disorders of lipoprotein metabolism	0.000	0.999	0.001
E78.6 Lipoprotein deficiency	0.000	0.999	0.001
E78.5 Hyperlipidaemia, unspecified	0.000	0.999	0.001
E78.4 Other hyperlipidaemia	0.000	0.999	0.001
E78.3 Hyperchylomicronaemia	0.000	0.999	0.001
E78.2 Mixed hyperlipidaemia	0.000	0.999	0.001
E78.1 Pure hyperglyceridaemia	0.000	0.999	0.001
Z09.8 Follow-up examination after other treatment for other conditions	0.001	0.999	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
N40-N51 Diseases of male genital organs	0.001	0.999	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.001	0.999	0.000
Z96.6 Presence of orthopaedic joint implants	0.001	0.999	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.001	0.999	0.000
Z86 Personal history of certain other diseases	0.001	0.999	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.001	0.999	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.001	0.999	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.001	0.999	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.001	0.999	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.001	0.999	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.001	0.999	0.000
L82 Seborrhoeic keratosis	0.001	0.999	0.000
Y83.8 Other surgical procedures	0.001	0.999	0.000
T81 Complications of procedures, not elsewhere classified	0.001	0.999	0.000
E70-E90 Metabolic disorders	0.000	0.999	0.001
T81.4 Infection following a procedure, not elsewhere classified	0.001	0.999	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.001	0.999	0.000
R31 Unspecified haematuria	0.001	0.999	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
G40.9 Epilepsy, unspecified	0.001	0.999	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.001	0.999	0.000
N50 Other disorders of male genital organs	0.001	0.999	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.001	0.999	0.000
N48 Other disorders of penis	0.001	0.999	0.000
N45 Orchitis and epididymitis	0.001	0.999	0.000
N43 Hydrocele and spermatocele	0.001	0.999	0.000
N42 Other disorders of prostate	0.001	0.999	0.000
N41 Inflammatory diseases of prostate	0.001	0.999	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.001	0.999	0.000
N46 Male infertility	0.001	0.999	0.000
N44 Torsion of testis	0.001	0.999	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.001	0.999	0.000
Y83.9 Surgical procedure, unspecified	0.001	0.999	0.000
Y83.5 Amputation of limb(s)	0.001	0.999	0.000
Y83.4 Other reconstructive surgery	0.001	0.999	0.000
Y83.3 Surgical operation with formation of external stoma	0.001	0.999	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.001	0.999	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.001	0.999	0.000
Y83.0 Surgical operation with transplant of whole organ	0.001	0.999	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.001	0.999	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.001	0.999	0.000
Z09.4 Follow-up examination after treatment of fracture	0.001	0.999	0.000
Z09.3 Follow-up examination after psychotherapy	0.001	0.999	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.001	0.999	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.001	0.999	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.001	0.999	0.000
K80 Cholelithiasis	0.001	0.999	0.000
R69 Unknown and unspecified causes of morbidity	0.001	0.999	0.000
Z13 Special screening examination for other diseases and disorders	0.001	0.999	0.000
Z12 Special screening examination for neoplasms	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999	0.000
Z10 Routine general health check-up of defined subpopulation	0.001	0.999	0.000
Z04 Examination and observation for other reasons	0.001	0.999	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.001	0.999	0.000
Z02 Examination and encounter for administrative purposes	0.001	0.999	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.001	0.999	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.001	0.999	0.000
Z96 Presence of other functional implants	0.001	0.999	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
Chapter XIV Diseases of the genitourinary system	0.001	0.999	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.001	0.999	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.001	0.999	0.000
Z86.0 Personal history of other neoplasms	0.001	0.999	0.000
G40 Epilepsy	0.001	0.999	0.000
K62.1 Rectal polyp	0.001	0.999	0.000
T81.9 Unspecified complication of procedure	0.001	0.999	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.001	0.999	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.001	0.999	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.001	0.999	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.001	0.999	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.001	0.999	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.001	0.999	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.001	0.999	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.999	0.001
E88 Other metabolic disorders	0.000	0.999	0.001
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.999	0.001
E85 Amyloidosis	0.000	0.999	0.001
E84 Cystic fibrosis	0.000	0.999	0.001
E83 Disorders of mineral metabolism	0.000	0.999	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.999	0.001
E79 Disorders of purine and pyrimidine metabolism	0.000	0.999	0.001
E77 Disorders of glycoprotein metabolism	0.000	0.999	0.001
E76 Disorders of glycosaminoglycan metabolism	0.000	0.999	0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.999	0.001
E74 Other disorders of carbohydrate metabolism	0.000	0.999	0.001
E73 Lactose intolerance	0.000	0.999	0.001
E72 Other disorders of amino-acid metabolism	0.000	0.999	0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.999	0.001
E70 Disorders of aromatic amino-acid metabolism	0.000	0.999	0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.999	0.001
E86 Volume depletion	0.000	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.001	0.999	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.001	0.999	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
G40-G47 Episodic and paroxysmal disorders	0.001	0.999	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.001	0.999	0.000
K51.9 Ulcerative colitis, unspecified	0.001	0.999	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.001	0.999	0.000
N41.8 Other inflammatory diseases of prostate	0.001	0.999	0.000
N41.3 Prostatocystitis	0.001	0.999	0.000
N41.2 Abscess of prostate	0.001	0.999	0.000
N41.1 Chronic prostatitis	0.001	0.999	0.000
N41.0 Acute prostatitis	0.001	0.999	0.000
N42.9 Disorder of prostate, unspecified	0.001	0.999	0.000
N42.8 Other specified disorders of prostate	0.001	0.999	0.000
N42.3 Dysplasia of prostate	0.001	0.999	0.000
N42.2 Atrophy of prostate	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.001	0.999	0.000
N42.0 Calculus of prostate	0.001	0.999	0.000
N43.4 Spermatocele	0.001	0.999	0.000
N43.3 Hydrocele, unspecified	0.001	0.999	0.000
N43.2 Other hydrocele	0.001	0.999	0.000
N43.1 Infected hydrocele	0.001	0.999	0.000
N43.0 Encysted hydrocele	0.001	0.999	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.001	0.999	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.001	0.999	0.000
N48.9 Disorder of penis, unspecified	0.001	0.999	0.000
N48.8 Other specified disorders of penis	0.001	0.999	0.000
N48.6 Balanitis xerotica obliterans	0.001	0.999	0.000
N48.5 Ulcer of penis	0.001	0.999	0.000
N48.4 Impotence of organic origin	0.001	0.999	0.000
N48.3 Priapism	0.001	0.999	0.000
N48.2 Other inflammatory disorders of penis	0.001	0.999	0.000
N48.1 Balanoposthitis	0.001	0.999	0.000
N48.0 Leukoplakia of penis	0.001	0.999	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.001	0.999	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.001	0.999	0.000
N49.2 Inflammatory disorders of scrotum	0.001	0.999	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.001	0.999	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.001	0.999	0.000
N50.9 Disorder of male genital organs, unspecified	0.001	0.999	0.000
N50.8 Other specified disorders of male genital organs	0.001	0.999	0.000
N50.1 Vascular disorders of male genital organs	0.001	0.999	0.000
N50.0 Atrophy of testis	0.001	0.999	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.001	0.999	0.000
N51.2 Balanitis in diseases classified elsewhere	0.001	0.999	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.001	0.999	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.001	0.999	0.000
Z96.9 Presence of functional implant, unspecified	0.001	0.999	0.000
Z96.8 Presence of other specified functional implants	0.001	0.999	0.000
Z96.7 Presence of other bone and tendon implants	0.001	0.999	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.001	0.999	0.000
Z96.4 Presence of endocrine implants	0.001	0.999	0.000
Z96.3 Presence of artificial larynx	0.001	0.999	0.000
Z96.2 Presence of otological and audiological implants	0.001	0.999	0.000
Z96.1 Presence of intraocular lens	0.001	0.999	0.000
Z96.0 Presence of urogenital implants	0.001	0.999	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.001	0.999	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.001	0.999	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.001	0.999	0.000
L94 Other localised connective tissue disorders	0.001	0.999	0.000
L93 Lupus erythematosus	0.001	0.999	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.001	0.999	0.000
L91 Hypertrophic disorders of skin	0.001	0.999	0.000
L90 Atrophic disorders of skin	0.001	0.999	0.000
L89 Decubitus ulcer	0.001	0.999	0.000
L87 Transepidermal elimination disorders	0.001	0.999	0.000
L85 Other epidermal thickening	0.001	0.999	0.000
L81 Other disorders of pigmentation	0.001	0.999	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.001	0.999	0.000
L88 Pyoderma gangrenosum	0.001	0.999	0.000
L86 Keratoderma in diseases classified elsewhere	0.001	0.999	0.000
L84 Corns and callosities	0.001	0.999	0.000
L83 Acanthosis nigricans	0.001	0.999	0.000
L80 Vitiligo	0.001	0.999	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.001	0.999	0.000
Chapter XXI Factors influencing health status and contact with health services	0.001	0.999	0.000
K80.3 Calculus of bile duct with cholangitis	0.001	0.999	0.000
K80.8 Other cholelithiasis	0.001	0.999	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.001	0.999	0.000
K80.4 Calculus of bile duct with cholecystitis	0.001	0.999	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.001	0.999	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.001	0.999	0.000
Z00.8 Other general examinations	0.001	0.999	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.001	0.999	0.000
Z00.5 Examination of potential donor of organ and tissue	0.001	0.999	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.001	0.999	0.000
Z00.3 Examination for adolescent development state	0.001	0.999	0.000
Z00.2 Examination for period of rapid growth in childhood	0.001	0.999	0.000
Z00.1 Routine child health examination	0.001	0.999	0.000
Z00.0 General medical examination	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.001	0.999	0.000
Z01.8 Other specified special examinations	0.001	0.999	0.000
Z01.7 Laboratory examination	0.001	0.999	0.000
Z01.6 Radiological examination, not elsewhere classified	0.001	0.999	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.001	0.999	0.000
Z01.4 Gynaecological examination (general)(routine)	0.001	0.999	0.000
Z01.3 Examination of blood pressure	0.001	0.999	0.000
Z01.2 Dental examination	0.001	0.999	0.000
Z01.1 Examination of ears and hearing	0.001	0.999	0.000
Z01.0 Examination of eyes and vision	0.001	0.999	0.000
Z02.9 Examination for administrative purposes, unspecified	0.001	0.999	0.000
Z02.8 Other examinations for administrative purposes	0.001	0.999	0.000
Z02.7 Issue of medical certificate	0.001	0.999	0.000
Z02.6 Examination for insurance purposes	0.001	0.999	0.000
Z02.5 Examination for participation in sport	0.001	0.999	0.000
Z02.4 Examination for driving licence	0.001	0.999	0.000
Z02.3 Examination for recruitment to armed forces	0.001	0.999	0.000
Z02.2 Examination for admission to residential institution	0.001	0.999	0.000
Z02.1 Pre-employment examination	0.001	0.999	0.000
Z02.0 Examination for admission to educational institution	0.001	0.999	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.001	0.999	0.000
Z03.8 Observation for other suspected diseases and conditions	0.001	0.999	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.001	0.999	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.001	0.999	0.000
Z03.4 Observation for suspected myocardial infarction	0.001	0.999	0.000
Z03.3 Observation for suspected nervous system disorder	0.001	0.999	0.000
Z03.2 Observation for suspected mental and behavioural disorders	0.001	0.999	0.000
Z03.1 Observation for suspected malignant neoplasm	0.001	0.999	0.000
Z03.0 Observation for suspected tuberculosis	0.001	0.999	0.000
Z04.9 Examination and observation for unspecified reason	0.001	0.999	0.000
Z04.8 Examination and observation for other specified reasons	0.001	0.999	0.000
Z04.6 General psychiatric examination, requested by authority	0.001	0.999	0.000
Z04.5 Examination and observation following other inflicted injury	0.001	0.999	0.000
Z04.4 Examination and observation following alleged rape and seduction	0.001	0.999	0.000
Z04.3 Examination and observation following other accident	0.001	0.999	0.000
Z04.2 Examination and observation following work accident	0.001	0.999	0.000
Z04.1 Examination and observation following transport accident	0.001	0.999	0.000
Z04.0 Blood-alcohol and blood-drug test	0.001	0.999	0.000
Z10.8 Routine general health check-up of other defined subpopulations	0.001	0.999	0.000
Z10.3 Routine general health check-up of sports teams	0.001	0.999	0.000
Z10.2 Routine general health check-up of armed forces	0.001	0.999	0.000
Z10.1 Routine general health check-up of inhabitants of institutions	0.001	0.999	0.000
Z10.0 Occupational health examination	0.001	0.999	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.001	0.999	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.001	0.999	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.001	0.999	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
Z11.2 Special screening examination for other bacterial diseases	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.001	0.999	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.001	0.999	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.001	0.999	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.001	0.999	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.001	0.999	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.001	0.999	0.000
Z12.3 Special screening examination for neoplasm of breast	0.001	0.999	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.001	0.999	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.001	0.999	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.001	0.999	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.001	0.999	0.000
Z13.9 Special screening examination, unspecified	0.001	0.999	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.001	0.999	0.000
Z13.5 Special screening examination for eye and ear disorders	0.001	0.999	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.001	0.999	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.001	0.999	0.000
Z13.2 Special screening examination for nutritional disorders	0.001	0.999	0.000
Z13.1 Special screening examination for diabetes mellitus	0.001	0.999	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.001	0.999	0.000
T86 Failure and rejection of transplanted organs and tissues	0.001	0.999	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.001	0.999	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.001	0.999	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
N99-N99 Other disorders of the genitourinary system	0.001	0.999	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.001	0.999	0.000
N60-N64 Disorders of breast	0.001	0.999	0.000
N25-N29 Other disorders of kidney and ureter	0.001	0.999	0.000
N20-N23 Urolithiasis	0.001	0.999	0.000
N17-N19 Renal failure	0.001	0.999	0.000
N10-N16 Renal tubulo-interstitial diseases	0.001	0.999	0.000
N00-N08 Glomerular diseases	0.001	0.999	0.000
R50-R69 General symptoms and signs	0.001	0.999	0.000
R30-R39 Symptoms and signs involving the urinary system	0.001	0.999	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.001	0.999	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999	0.001
# Top node	0.001	0.999	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.999	0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.999	0.001
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.999	0.001
E70.3 Albinism	0.000	0.999	0.001
E70.2 Disorders of tyrosine metabolism	0.000	0.999	0.001
E70.1 Other hyperphenylalaninaemias	0.000	0.999	0.001
E70.0 Classical phenylketonuria	0.000	0.999	0.001
E71.3 Disorders of fatty-acid metabolism	0.000	0.999	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.999	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.999	0.001
E71.0 Maple-syrup-urine disease	0.000	0.999	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.999	0.001
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.999	0.001
E72.5 Disorders of glycine metabolism	0.000	0.999	0.001
E72.4 Disorders of ornithine metabolism	0.000	0.999	0.001
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.999	0.001
E72.2 Disorders of urea cycle metabolism	0.000	0.999	0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.999	0.001
E72.0 Disorders of amino-acid transport	0.000	0.999	0.001
E73.9 Lactose intolerance, unspecified	0.000	0.999	0.001
E73.8 Other lactose intolerance	0.000	0.999	0.001
E73.1 Secondary lactase deficiency	0.000	0.999	0.001
E73.0 Congenital lactase deficiency	0.000	0.999	0.001
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.999	0.001
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.999	0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.999	0.001
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.999	0.001
E74.2 Disorders of galactose metabolism	0.000	0.999	0.001
E74.1 Disorders of fructose metabolism	0.000	0.999	0.001
E74.0 Glycogen storage disease	0.000	0.999	0.001
E75.6 Lipid storage disorder, unspecified	0.000	0.999	0.001
E75.5 Other lipid storage disorders	0.000	0.999	0.001
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.999	0.001
E75.3 Sphingolipidosis, unspecified	0.000	0.999	0.001
E75.2 Other sphingolipidosis	0.000	0.999	0.001
E75.1 Other gangliosidosis	0.000	0.999	0.001
E75.0 GM2 gangliosidosis	0.000	0.999	0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.999	0.001
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.999	0.001
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.999	0.001
E76.2 Other mucopolysaccharidoses	0.000	0.999	0.001
E76.1 Mucopolysaccharidosis, type II	0.000	0.999	0.001
E76.0 Mucopolysaccharidosis, type I	0.000	0.999	0.001
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.999	0.001
E77.8 Other disorders of glycoprotein metabolism	0.000	0.999	0.001
E77.1 Defects in glycoprotein degradation	0.000	0.999	0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.999	0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.999	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.999	0.001
E79.1 Lesch-Nyhan syndrome	0.000	0.999	0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.999	0.001
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.999	0.001
E80.6 Other disorders of bilirubin metabolism	0.000	0.999	0.001
E80.5 Crigler-Najjar syndrome	0.000	0.999	0.001
E80.4 Gilbert's syndrome	0.000	0.999	0.001
E80.3 Defects of catalase and peroxydase	0.000	0.999	0.001
E80.2 Other porphyria	0.000	0.999	0.001
E80.1 Porphyria cutanea tarda	0.000	0.999	0.001
E80.0 Hereditary erythropoietic porphyria	0.000	0.999	0.001
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.999	0.001
E83.8 Other disorders of mineral metabolism	0.000	0.999	0.001
E83.5 Disorders of calcium metabolism	0.000	0.999	0.001
E83.4 Disorders of magnesium metabolism	0.000	0.999	0.001
E83.3 Disorders of phosphorus metabolism	0.000	0.999	0.001
E83.2 Disorders of zinc metabolism	0.000	0.999	0.001
E83.1 Disorders of iron metabolism	0.000	0.999	0.001
E83.0 Disorders of copper metabolism	0.000	0.999	0.001
E84.9 Cystic fibrosis, unspecified	0.000	0.999	0.001
E84.8 Cystic fibrosis with other manifestations	0.000	0.999	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.999	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.999	0.001
E85.9 Amyloidosis, unspecified	0.000	0.999	0.001
E85.8 Other amyloidosis	0.000	0.999	0.001
E85.4 Organ-limited amyloidosis	0.000	0.999	0.001
E85.3 Secondary systemic amyloidosis	0.000	0.999	0.001
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.999	0.001
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.999	0.001
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.999	0.001
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.999	0.001
E87.7 Fluid overload	0.000	0.999	0.001
E87.6 Hypokalaemia	0.000	0.999	0.001
E87.5 Hyperkalaemia	0.000	0.999	0.001
E87.4 Mixed disorder of acid-base balance	0.000	0.999	0.001
E87.3 Alkalosis	0.000	0.999	0.001
E87.2 Acidosis	0.000	0.999	0.001
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.999	0.001
E87.0 Hyperosmolality and hypernatraemia	0.000	0.999	0.001
E88.9 Metabolic disorder, unspecified	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.000	0.999	0.001
E88.3 Tumour lysis syndrome	0.000	0.999	0.001
E88.2 Lipomatosis, not elsewhere classified	0.000	0.999	0.001
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.999	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.999	0.001
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.999	0.001
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.999	0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.999	0.001
E89.5 Postprocedural testicular hypofunction	0.000	0.999	0.001
E89.4 Postprocedural ovarian failure	0.000	0.999	0.001
E89.3 Postprocedural hypopituitarism	0.000	0.999	0.001
E89.2 Postprocedural hypoparathyroidism	0.000	0.999	0.001
E89.1 Postprocedural hypoinsulinaemia	0.000	0.999	0.001
E89.0 Postprocedural hypothyroidism	0.000	0.999	0.001
G40.8 Other epilepsy	0.001	0.999	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.001	0.999	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.001	0.999	0.000
G40.5 Special epileptic syndromes	0.001	0.999	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.001	0.999	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.001	0.999	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.001	0.999	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.001	0.999	0.000
G47 Sleep disorders	0.001	0.999	0.000
K62 Other diseases of anus and rectum	0.001	0.999	0.000
L60-L75 Disorders of skin appendages	0.001	0.999	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.001	0.999	0.000
L50-L54 Urticaria and erythema	0.001	0.999	0.000
L40-L45 Papulosquamous disorders	0.001	0.999	0.000
L20-L30 Dermatitis and eczema	0.001	0.999	0.000
L10-L14 Bullous disorders	0.001	0.999	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.999	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.001	0.999	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.001	0.999	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.001	0.999	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.999	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.001	0.999	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999	0.000
Y35-Y36 Legal intervention and operations of war	0.001	0.999	0.000
Y10-Y34 Event of undetermined intent	0.001	0.999	0.000
Y00-Y09 Assault	0.001	0.999	0.000
X85-X99 Assault	0.001	0.999	0.000
X60-X84 Intentional self-harm	0.001	0.999	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.001	0.999	0.000
X50-X57 Overexertion, travel and privation	0.001	0.999	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999	0.000
X30-X39 Exposure to forces of nature	0.001	0.999	0.000
X20-X29 Contact with venomous animals and plants	0.001	0.999	0.000
X10-X19 Contact with heat and hot substances	0.001	0.999	0.000
X00-X09 Exposure to smoke, fire and flames	0.001	0.999	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.001	0.999	0.000
W75-W84 Other accidental threats to breathing	0.001	0.999	0.000
W65-W74 Accidental drowning and submersion	0.001	0.999	0.000
W50-W64 Exposure to animate mechanical forces	0.001	0.999	0.000
W20-W49 Exposure to inanimate mechanical forces	0.001	0.999	0.000
W00-W19 Falls	0.001	0.999	0.000
V98-V99 Other and unspecified transport accidents	0.001	0.999	0.000
V95-V97 Air and space transport accidents	0.001	0.999	0.000
V90-V94 Water transport accidents	0.001	0.999	0.000
V80-V89 Other land transport accidents	0.001	0.999	0.000
V70-V79 Bus occupant injured in transport accident	0.001	0.999	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.001	0.999	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.001	0.999	0.000
V40-V49 Car occupant injured in transport accident	0.001	0.999	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.001	0.999	0.000
V20-V29 Motorcycle rider injured in transport accident	0.001	0.999	0.000
V10-V19 Pedal cyclist injured in transport accident	0.001	0.999	0.000
V01-V09 Pedestrian injured in transport accident	0.001	0.999	0.000
Chapter VI Diseases of the nervous system	0.001	0.999	0.000
Y84.9 Medical procedure, unspecified	0.001	0.999	0.000
Y84.8 Other medical procedures	0.001	0.999	0.000
Y84.7 Blood-sampling	0.001	0.999	0.000
Y84.6 Urinary catheterisation	0.001	0.999	0.000
Y84.5 Insertion of gastric or duodenal sound	0.001	0.999	0.000
Y84.4 Aspiration of fluid	0.001	0.999	0.000
Y84.3 Shock therapy	0.001	0.999	0.000
Y84.2 Radiological procedure and radiotherapy	0.001	0.999	0.000
Y84.1 Kidney dialysis	0.001	0.999	0.000
Y84.0 Cardiac catheterisation	0.001	0.999	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.001	0.999	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.001	0.999	0.000
G44 Other headache syndromes	0.001	0.999	0.000
G43 Migraine	0.001	0.999	0.000
G41 Status epilepticus	0.001	0.999	0.000
K51 Ulcerative colitis	0.001	0.999	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.001	0.999	0.000
K86 Other diseases of pancreas	0.001	0.999	0.000
K85 Acute pancreatitis	0.001	0.999	0.000
K83 Other diseases of biliary tract	0.001	0.999	0.000
K82 Other diseases of gallbladder	0.001	0.999	0.000
K81 Cholecystitis	0.001	0.999	0.000
R42 Dizziness and giddiness	0.001	0.999	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.001	0.999	0.000
E00-E07 Disorders of thyroid gland	0.001	0.999	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000
T79-T79 Certain early complications of trauma	0.001	0.999	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
T33-T35 Frostbite	0.001	0.999	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.001	0.999	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.999	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999	0.000
T00-T07 Injuries involving multiple body regions	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.001	0.999	0.000
S80-S89 Injuries to the knee and lower leg	0.001	0.999	0.000
S70-S79 Injuries to the hip and thigh	0.001	0.999	0.000
S60-S69 Injuries to the wrist and hand	0.001	0.999	0.000
S50-S59 Injuries to the elbow and forearm	0.001	0.999	0.000
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999	0.000
S20-S29 Injuries to the thorax	0.001	0.999	0.000
S10-S19 Injuries to the neck	0.001	0.999	0.000
S00-S09 Injuries to the head	0.001	0.999	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.001	0.999	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.001	0.999	0.000
Chapter XI Diseases of the digestive system	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations