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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117604355
log Bayes Factor = 8.1344
Chromosome 16   position 82,276,031  (GRCh37) Explore rs117604355 on Ensembl!
Variant rs117604355 is part of Cluster X0141

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
M54.5 Low back pain
0.997 0.003 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.987 0.013 0.000
O60-O75 Complications of labour and delivery
0.985 0.015 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.983 0.017 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.983 0.017 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.970 0.030 0.000
M54.56 Low back pain (Lumbar region)
0.970 0.030 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.964 0.036 0.000
T39.1 4-Aminophenol derivatives
0.960 0.040 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.953 0.047 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.950 0.050 0.000
Chapter XX External causes of morbidity and mortality
0.943 0.057 0.000
R20 Disturbances of skin sensation
0.941 0.059 0.000
M51 Other intervertebral disk disorders
0.941 0.059 0.000
S32 Fracture of lumbar spine and pelvis
0.938 0.062 0.000
M80-M85 Disorders of bone density and structure
0.937 0.063 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.936 0.064 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.934 0.066 0.000
F00 Dementia in Alzheimer's disease
0.931 0.069 0.000
R00 Abnormalities of heart beat
0.931 0.069 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.923 0.077 0.000
Chapter VI Diseases of the nervous system
0.923 0.077 0.000
M86-M90 Other osteopathies
0.920 0.080 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.920 0.080 0.000
M54.4 Lumbago with sciatica
0.918 0.082 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.914 0.086 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.913 0.087 0.000
F03 Unspecified dementia
0.912 0.088 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.912 0.088 0.000
R00.1 Bradycardia, unspecified
0.908 0.092 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.903 0.097 0.000
T51 Toxic effect of alcohol
0.900 0.100 0.000
R47-R49 Symptoms and signs involving speech and voice
0.896 0.104 0.000
M54.57 Low back pain (Lumbosacral region)
0.895 0.105 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.894 0.106 0.000
R04 Haemorrhage from respiratory passages
0.892 0.108 0.000
O72 Postpartum haemorrhage
0.887 0.113 0.000
M60-M63 Disorders of muscles
0.886 0.114 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.885 0.115 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.885 0.115 0.000
R20.2 Paraesthesia of skin
0.882 0.118 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.876 0.124 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.875 0.125 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.868 0.132 0.000
F05.9 Delirium, unspecified
0.868 0.132 0.000
T39.0 Salicylates
0.868 0.132 0.000
M80 Osteoporosis with pathological fracture
0.867 0.133 0.000
T43.2 Other and unspecified antidepressants
0.865 0.135 0.000
Q50-Q56 Congenital malformations of genital organs
0.863 0.137 0.000
R47 Speech disturbances, not elsewhere classified
0.862 0.138 0.000
O62 Abnormalities of forces of labour
0.860 0.140 0.000
T51.9 Alcohol, unspecified
0.860 0.140 0.000
G30-G32 Other degenerative diseases of the nervous system
0.858 0.142 0.000
S32.5 Fracture of pubis
0.857 0.143 0.000
O80-O84 Delivery
0.856 0.144 0.000
R26 Abnormalities of gait and mobility
0.855 0.145 0.000
Q60-Q64 Congenital malformations of the urinary system
0.853 0.147 0.000
X60-X84 Intentional self-harm
0.853 0.147 0.000
F20 Schizophrenia
0.852 0.148 0.000
W20-W49 Exposure to inanimate mechanical forces
0.852 0.148 0.000
S90-S99 Injuries to the ankle and foot
0.850 0.150 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.849 0.151 0.000
M51.2 Other specified intervertebral disk displacement
0.848 0.152 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.846 0.154 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.844 0.156 0.000
O85-O92 Complications predominantly related to the puerperium
0.843 0.157 0.000
R04.2 Haemoptysis
0.841 0.159 0.000
M91-M94 Chondropathies
0.838 0.162 0.000
G70-G73 Diseases of myoneural junction and muscle
0.838 0.162 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.834 0.166 0.000
O73 Retained placenta and membranes, without haemorrhage
0.832 0.168 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.831 0.169 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.827 0.173 0.000
G30 Alzheimer's disease
0.822 0.178 0.000
R47.0 Dysphasia and aphasia
0.818 0.182 0.000
Chapter X Diseases of the respiratory system
0.815 0.185 0.000
L20-L30 Dermatitis and eczema
0.815 0.185 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.814 0.186 0.000
M89 Other disorders of bone
0.814 0.186 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.813 0.187 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.812 0.188 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.811 0.189 0.000
M54.6 Pain in thoracic spine
0.810 0.190 0.000
R00.2 Palpitations
0.810 0.190 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.807 0.193 0.000
O72.1 Other immediate postpartum haemorrhage
0.806 0.194 0.000
O61 Failed induction of labour
0.805 0.195 0.000
M54.2 Cervicalgia
0.803 0.197 0.000
M82 Osteoporosis in diseases classified elsewhere
0.803 0.197 0.000
O71 Other obstetric trauma
0.799 0.201 0.000
S32.50 Fracture of pubis (closed)
0.799 0.201 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.794 0.206 0.000
S92 Fracture of foot, except ankle
0.792 0.208 0.000
S32.1 Fracture of sacrum
0.792 0.208 0.000
G30.9 Alzheimer's disease, unspecified
0.786 0.214 0.000
Chapter VII Diseases of the eye and adnexa
0.786 0.214 0.000
M51.9 Intervertebral disk disorder, unspecified
0.785 0.215 0.000
M54.55 Low back pain (Thoracolumbar region)
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.785 0.215 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.782 0.218 0.000
O44 Placenta praevia
0.782 0.218 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.782 0.218 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.781 0.219 0.000
M62 Other disorders of muscle
0.780 0.220 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.778 0.222 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.778 0.222 0.000
F20.9 Schizophrenia, unspecified
0.777 0.223 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.776 0.223 0.000
G40-G47 Episodic and paroxysmal disorders
0.776 0.224 0.000
O62.0 Primary inadequate contractions
0.775 0.225 0.000
M85 Other disorders of bone density and structure
0.773 0.227 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.771 0.229 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.771 0.229 0.000
L27 Dermatitis due to substances taken internally
0.769 0.231 0.000
S36 Injury of intra-abdominal organs
0.768 0.232 0.000
T45.0 Antiallergic and antiemetic drugs
0.767 0.233 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.762 0.238 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.760 0.240 0.000
M54.9 Dorsalgia, unspecified
0.760 0.240 0.000
F60-F69 Disorders of adult personality and behaviour
0.758 0.242 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.758 0.242 0.000
S92.0 Fracture of calcaneus
0.756 0.244 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.755 0.245 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.752 0.248 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.752 0.248 0.000
S40-S49 Injuries to the shoulder and upper arm
0.751 0.249 0.000
M54.50 Low back pain (Multiple sites in spine)
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.750 0.250 0.000
G70 Myasthenia gravis and other myoneural disorders
0.749 0.251 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.748 0.252 0.000
O32.2 Maternal care for transverse and oblique lie
0.748 0.252 0.000
M53 Other dorsopathies, not elsewhere classified
0.744 0.256 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.744 0.256 0.000
R40 Somnolence, stupor and coma
0.743 0.257 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.743 0.257 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.742 0.258 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.740 0.260 0.000
S32.0 Fracture of lumbar vertebra
0.739 0.261 0.000
M88 Paget's disease of bone [osteitis deformans]
0.738 0.261 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.738 0.262 0.000
O82 Single delivery by Caesarean section
0.737 0.262 0.000
R47.1 Dysarthria and anarthria
0.737 0.263 0.000
O42 Premature rupture of membranes
0.737 0.263 0.000
Chapter I Certain infectious and parasitic diseases
0.735 0.265 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.735 0.265 0.000
W50-W64 Exposure to animate mechanical forces
0.735 0.265 0.000
T51.0 Ethanol
0.734 0.266 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.733 0.267 0.000
O32.0 Maternal care for unstable lie
0.732 0.268 0.000
J95-J99 Other diseases of the respiratory system
0.731 0.269 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
O66 Other obstructed labour
0.730 0.270 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.730 0.270 0.000
O70 Perineal laceration during delivery
0.730 0.270 0.000
S92.00 Fracture of calcaneus (closed)
0.730 0.270 0.000
O32.8 Maternal care for other malpresentation of foetus
0.726 0.273 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.726 0.274 0.000
M00-M03 Infectious arthropathies
0.726 0.274 0.000
S31 Open wound of abdomen, lower back and pelvis
0.725 0.275 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.725 0.275 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.724 0.276 0.000
Q61 Cystic kidney disease
0.723 0.277 0.000
T90 Sequelae of injuries of head
0.723 0.277 0.000
O73.0 Retained placenta, without haemorrhage
0.723 0.277 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
M87 Osteonecrosis
0.720 0.279 0.000
R01 Cardiac murmurs and other cardiac sounds
0.719 0.281 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.718 0.282 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
L50-L54 Urticaria and erythema
0.716 0.284 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.716 0.284 0.000
M54.54 Low back pain-Thoracic
0.714 0.285 0.000
M54.53 Low back pain-Cervicothoracic
0.714 0.285 0.000
M54.52 Low back pain-Cervical
0.714 0.285 0.000
M54.51 Low back pain-Occipit-atl-axl
0.714 0.285 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.713 0.287 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.713 0.287 0.000
T39.4 Antirheumatics, not elsewhere classified
0.713 0.287 0.000
T39.2 Pyrazolone derivatives
0.713 0.287 0.000
Y40 Systemic antibiotics
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
T43.9 Psychotropic drug, unspecified
0.708 0.292 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
T43.6 Psychostimulants with abuse potential
0.708 0.292 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.708 0.292 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.708 0.292 0.000
M82.1 Osteoporosis in endocrine disorders
0.707 0.293 0.000
F29 Unspecified nonorganic psychosis
0.707 0.293 0.000
O74 Complications of anaesthesia during labour and delivery
0.706 0.294 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.706 0.294 0.000
O60 Preterm delivery
0.706 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.295 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.705 0.295 0.000
F02 Dementia in other diseases classified elsewhere
0.705 0.295 0.000
F09 Unspecified organic or symptomatic mental disorder
0.705 0.295 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.705 0.295 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.295 0.000
L60-L75 Disorders of skin appendages
0.705 0.295 0.000
M62.8 Other specified disorders of muscle
0.704 0.296 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.704 0.296 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.703 0.297 0.000
J60-J70 Lung diseases due to external agents
0.703 0.297 0.000
M54.1 Radiculopathy
0.703 0.297 0.000
T14 Injury of unspecified body region
0.702 0.297 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.702 0.298 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.701 0.299 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.700 0.300 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.699 0.301 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.699 0.301 0.000
M90 Osteopathies in diseases classified elsewhere
0.698 0.302 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.698 0.302 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.697 0.303 0.000
M20-M25 Other joint disorders
0.697 0.303 0.000
F20.5 Residual schizophrenia
0.696 0.304 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.696 0.304 0.000
S37 Injury of urinary and pelvic organs
0.696 0.304 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.696 0.304 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.696 0.304 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.696 0.304 0.000
F05.8 Other delirium
0.696 0.304 0.000
W29 Contact with other powered hand tools and household machinery
0.695 0.305 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.695 0.305 0.000
M60 Myositis
0.694 0.306 0.000
O43 Placental disorders
0.691 0.308 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.691 0.309 0.000
Q35-Q37 Cleft lip and cleft palate
0.691 0.309 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.691 0.309 0.000
W22 Striking against or struck by other objects
0.689 0.311 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.688 0.312 0.000
M51.8 Other specified intervertebral disk disorders
0.688 0.312 0.000
T18 Foreign body in alimentary tract
0.688 0.312 0.000
S32.10 Fracture of sacrum (closed)
0.687 0.313 0.000
G43 Migraine
0.687 0.313 0.000
O47 False labour
0.687 0.313 0.000
G70.0 Myasthenia gravis
0.685 0.315 0.000
Y00-Y09 Assault
0.684 0.316 0.000
S32.4 Fracture of acetabulum
0.683 0.316 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.683 0.317 0.000
M89.9 Disorder of bone, unspecified
0.682 0.318 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.681 0.319 0.000
Q63 Other congenital malformations of kidney
0.681 0.319 0.000
F22 Persistent delusional disorders
0.680 0.320 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.680 0.320 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.680 0.320 0.000
X62.9 Unspecified place
0.680 0.320 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.680 0.320 0.000
O90 Complications of the puerperium, not elsewhere classified
0.679 0.321 0.000
O86 Other puerperal infections
0.679 0.321 0.000
M54.22 Cervicalgia (Cervical region)
0.678 0.322 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.678 0.322 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.677 0.323 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.677 0.323 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.677 0.323 0.000
O61.0 Failed medical induction of labour
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.676 0.324 0.000
Y10-Y34 Event of undetermined intent
0.676 0.324 0.000
X85-X99 Assault
0.676 0.324 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.676 0.324 0.000
X30-X39 Exposure to forces of nature
0.676 0.324 0.000
X10-X19 Contact with heat and hot substances
0.676 0.324 0.000
X00-X09 Exposure to smoke, fire and flames
0.676 0.324 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.676 0.324 0.000
W75-W84 Other accidental threats to breathing
0.676 0.324 0.000
W65-W74 Accidental drowning and submersion
0.676 0.324 0.000
V98-V99 Other and unspecified transport accidents
0.676 0.324 0.000
V95-V97 Air and space transport accidents
0.676 0.324 0.000
V90-V94 Water transport accidents
0.676 0.324 0.000
V70-V79 Bus occupant injured in transport accident
0.676 0.324 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.676 0.324 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.676 0.324 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.676 0.324 0.000
V01-V09 Pedestrian injured in transport accident
0.676 0.324 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.676 0.324 0.000
J09-J18 Influenza and pneumonia
0.676 0.324 0.000
M24 Other specific joint derangements
0.676 0.324 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.676 0.324 0.000
R23 Other skin changes
0.676 0.324 0.000
X50-X57 Overexertion, travel and privation
0.676 0.324 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.675 0.325 0.000
R20.3 Hyperaesthesia
0.675 0.325 0.000
R20.1 Hypoaesthesia of skin
0.675 0.325 0.000
R20.0 Anaesthesia of skin
0.675 0.325 0.000
M51.3 Other specified intervertebral disk degeneration
0.675 0.325 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.675 0.325 0.000
M51.4 Schmorl's nodes
0.675 0.325 0.000
M93 Other osteochondropathies
0.674 0.326 0.000
S32.3 Fracture of ilium
0.672 0.328 0.000
S32.2 Fracture of coccyx
0.672 0.328 0.000
M65-M68 Disorders of synovium and tendon
0.672 0.328 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.672 0.328 0.000
M83 Adult osteomalacia
0.671 0.328 0.000
T65 Toxic effect of other and unspecified substances
0.671 0.329 0.000
T62 Toxic effect of other noxious substances eaten as food
0.671 0.329 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.671 0.329 0.000
T60 Toxic effect of pesticides
0.671 0.329 0.000
T57 Toxic effect of other inorganic substances
0.671 0.329 0.000
T56 Toxic effect of metals
0.671 0.329 0.000
T54 Toxic effect of corrosive substances
0.671 0.329 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.671 0.329 0.000
T52 Toxic effect of organic solvents
0.671 0.329 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.671 0.329 0.000
T55 Toxic effect of soaps and detergents
0.671 0.329 0.000
M85.6 Other cyst of bone
0.671 0.329 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.670 0.330 0.000
M94 Other disorders of cartilage
0.670 0.330 0.000
T45.5 Anticoagulants
0.670 0.330 0.000
W45 Foreign body or object entering through skin
0.670 0.330 0.000
S60-S69 Injuries to the wrist and hand
0.670 0.330 0.000
O82.1 Delivery by emergency Caesarean section
0.669 0.331 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.669 0.331 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.668 0.332 0.000
T20 Burn and corrosion of head and neck
0.668 0.332 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.668 0.332 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.668 0.332 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.668 0.332 0.000
T79-T79 Certain early complications of trauma
0.667 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.667 0.333 0.000
T58 Toxic effect of carbon monoxide
0.667 0.333 0.000
R40.2 Coma, unspecified
0.667 0.333 0.000
R76 Other abnormal immunological findings in serum
0.667 0.333 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.666 0.334 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.664 0.336 0.000
L28 Lichen simplex chronicus and prurigo
0.661 0.339 0.000
F05.1 Delirium superimposed on dementia
0.660 0.340 0.000
F05.0 Delirium not superimposed on dementia, so described
0.660 0.340 0.000
Q54 Hypospadias
0.659 0.340 0.000
S20-S29 Injuries to the thorax
0.659 0.341 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.658 0.341 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.658 0.341 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.658 0.341 0.000
M54.44 Lumbago with sciatica-Thoracic
0.658 0.341 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.658 0.341 0.000
M54.42 Lumbago with sciatica-Cervical
0.658 0.341 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.658 0.341 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.658 0.341 0.000
O44.1 Placenta praevia with haemorrhage
0.658 0.342 0.000
O81 Single delivery by forceps and vacuum extractor
0.657 0.343 0.000
T13 Other injuries of lower limb, level unspecified
0.656 0.343 0.000
O70.2 Third degree perineal laceration during delivery
0.656 0.344 0.000
Q53 Undescended testicle
0.656 0.344 0.000
O40 Polyhydramnios
0.656 0.344 0.000
O45 Premature separation of placenta [abruptio placentae]
0.655 0.345 0.000
O33 Maternal care for known or suspected disproportion
0.655 0.345 0.000
O31 Complications specific to multiple gestation
0.655 0.345 0.000
F28 Other nonorganic psychotic disorders
0.655 0.345 0.000
F24 Induced delusional disorder
0.655 0.345 0.000
F21 Schizotypal disorder
0.655 0.345 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.654 0.346 0.000
O71.8 Other specified obstetric trauma
0.653 0.346 0.000
G30.0 Alzheimer's disease with early onset
0.653 0.347 0.000
D60-D64 Aplastic and other anaemias
0.653 0.347 0.000
L20 Atopic dermatitis
0.652 0.348 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.652 0.348 0.000
T66-T78 Other and unspecified effects of external causes
0.650 0.349 0.000
R26.3 Immobility
0.650 0.350 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.649 0.351 0.000
F80-F89 Disorders of psychological development
0.649 0.351 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.648 0.351 0.000
X20-X29 Contact with venomous animals and plants
0.648 0.352 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.648 0.352 0.000
T63 Toxic effect of contact with venomous animals
0.646 0.353 0.000
R77 Other abnormalities of plasma proteins
0.646 0.354 0.000
M54.59 Low back pain (Site unspecified)
0.645 0.355 0.000
T51.8 Other alcohols
0.645 0.355 0.000
T51.3 Fusel oil
0.645 0.355 0.000
T51.2 2-Propanol
0.645 0.355 0.000
T51.1 Methanol
0.645 0.355 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.644 0.356 0.000
F01 Vascular dementia
0.644 0.356 0.000
H43-H45 Disorders of vitreous body and globe
0.643 0.357 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.643 0.357 0.000
W20 Struck by thrown, projected or falling object
0.643 0.357 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.642 0.357 0.000
G71 Primary disorders of muscles
0.642 0.358 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.642 0.358 0.000
G72 Other myopathies
0.642 0.358 0.000
Q51 Congenital malformations of uterus and cervix
0.641 0.359 0.000
J69 Pneumonitis due to solids and liquids
0.641 0.359 0.000
M24.1 Other articular cartilage disorders
0.640 0.360 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.639 0.361 0.000
R04.1 Haemorrhage from throat
0.639 0.361 0.000
F20.0 Paranoid schizophrenia
0.636 0.364 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.636 0.364 0.000
O72.3 Postpartum coagulation defects
0.636 0.364 0.000
J98 Other respiratory disorders
0.636 0.364 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.635 0.364 0.000
M61 Calcification and ossification of muscle
0.635 0.364 0.000
F99-F99 Unspecified mental disorder
0.635 0.365 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.635 0.365 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.635 0.365 0.000
X78 Intentional self-harm by sharp object
0.634 0.365 0.000
R06 Abnormalities of breathing
0.633 0.367 0.000
L53 Other erythematous conditions
0.632 0.368 0.000
T59 Toxic effect of other gases, fumes and vapours
0.632 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.368 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.631 0.369 0.000
S80-S89 Injuries to the knee and lower leg
0.629 0.371 0.000
F23 Acute and transient psychotic disorders
0.628 0.371 0.000
L10-L14 Bullous disorders
0.628 0.372 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.628 0.372 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.627 0.373 0.000
T45.8 Other primarily systemic and haematological agents
0.627 0.373 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.627 0.373 0.000
T45.6 Fibrinolysis-affecting drugs
0.627 0.373 0.000
T45.4 Iron and its compounds
0.627 0.373 0.000
T45.3 Enzymes, not elsewhere classified
0.627 0.373 0.000
T45.2 Vitamins, not elsewhere classified
0.627 0.373 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.627 0.373 0.000
M81 Osteoporosis without pathological fracture
0.627 0.373 0.000
V10-V19 Pedal cyclist injured in transport accident
0.627 0.373 0.000
M89.0 Algoneurodystrophy
0.627 0.373 0.000
F25 Schizoaffective disorders
0.626 0.373 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.626 0.374 0.000
V20-V29 Motorcycle rider injured in transport accident
0.625 0.374 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.625 0.374 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.623 0.376 0.000
O62.3 Precipitate labour
0.623 0.376 0.000
L71 Rosacea
0.623 0.377 0.000
V40-V49 Car occupant injured in transport accident
0.623 0.377 0.000
J90-J94 Other diseases of pleura
0.623 0.377 0.000
Y59 Other and unspecified vaccines and biological substances
0.622 0.378 0.000
Y58 Bacterial vaccines
0.622 0.378 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.622 0.378 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.622 0.378 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.622 0.378 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.622 0.378 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.622 0.378 0.000
Y48 Anaesthetics and therapeutic gases
0.622 0.378 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.622 0.378 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.622 0.378 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.621 0.379 0.000
M80.8 Other osteoporosis with pathological fracture
0.621 0.379 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.621 0.379 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.621 0.379 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.621 0.379 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.621 0.379 0.000
M89.5 Osteolysis
0.621 0.379 0.000
Y40.8 Other systemic antibiotics
0.619 0.380 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.619 0.381 0.000
Q55 Other congenital malformations of male genital organs
0.619 0.381 0.000
Q52 Other congenital malformations of female genitalia
0.619 0.381 0.000
G43.9 Migraine, unspecified
0.618 0.382 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.618 0.382 0.000
T17 Foreign body in respiratory tract
0.618 0.382 0.000
O87 Venous complications in the puerperium
0.618 0.382 0.000
R01.0 Benign and innocent cardiac murmurs
0.618 0.382 0.000
M89.8 Other specified disorders of bone
0.617 0.383 0.000
O80 Single spontaneous delivery
0.617 0.383 0.000
O62.9 Abnormality of forces of labour, unspecified
0.617 0.383 0.000
O62.8 Other abnormalities of forces of labour
0.617 0.383 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.617 0.383 0.000
O62.1 Secondary uterine inertia
0.617 0.383 0.000
T90.8 Sequelae of other specified injuries of head
0.616 0.383 0.000
Y44.2 Anticoagulants
0.616 0.384 0.000
M86 Osteomyelitis
0.616 0.384 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.615 0.384 0.000
S32.51 Fracture of pubis (open)
0.614 0.385 0.000
O84 Multiple delivery
0.614 0.386 0.000
O83 Other assisted single delivery
0.614 0.386 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.614 0.386 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.614 0.386 0.000
R26.1 Paralytic gait
0.613 0.387 0.000
G20-G26 Extrapyramidal and movement disorders
0.613 0.387 0.000
S70-S79 Injuries to the hip and thigh
0.613 0.387 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.612 0.388 0.000
Q64 Other congenital malformations of urinary system
0.612 0.388 0.000
X84 Intentional self-harm by unspecified means
0.611 0.389 0.000
X83 Intentional self-harm by other specified means
0.611 0.389 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.611 0.389 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.611 0.389 0.000
X80 Intentional self-harm by jumping from a high place
0.611 0.389 0.000
X79 Intentional self-harm by blunt object
0.611 0.389 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.611 0.389 0.000
X76 Intentional self-harm by smoke, fire and flames
0.611 0.389 0.000
X75 Intentional self-harm by explosive material
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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