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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16970670
log Bayes Factor = 6.69072
Chromosome 16   position 72,225,187  (GRCh37) Explore rs16970670 on Ensembl!
Variant rs16970670 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
# Top node
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.990 0.010 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.989 0.011 0.000
I21 Acute myocardial infarction
0.988 0.012 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.981 0.019 0.000
Chapter X Diseases of the respiratory system
0.975 0.025 0.000
H18 Other disorders of cornea
0.974 0.026 0.000
I25.2 Old myocardial infarction
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.971 0.029 0.000
E78.0 Pure hypercholesterolaemia
0.970 0.030 0.000
I24 Other acute ischaemic heart diseases
0.967 0.033 0.000
E78.5 Hyperlipidaemia, unspecified
0.967 0.033 0.000
I73 Other peripheral vascular diseases
0.966 0.034 0.000
I21.4 Acute subendocardial myocardial infarction
0.958 0.042 0.000
I73.9 Peripheral vascular disease, unspecified
0.956 0.044 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.955 0.045 0.000
M50-M54 Other dorsopathies
0.946 0.054 0.000
H18.5 Hereditary corneal dystrophies
0.943 0.057 0.000
H30-H36 Disorders of choroid and retina
0.938 0.062 0.000
M54 Dorsalgia
0.936 0.064 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.934 0.066 0.000
H53-H54 Visual disturbances and blindness
0.932 0.068 0.000
E70-E90 Metabolic disorders
0.932 0.068 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.931 0.069 0.000
Chapter I Certain infectious and parasitic diseases
0.926 0.074 0.000
I22 Subsequent myocardial infarction
0.923 0.077 0.000
I77 Other disorders of arteries and arterioles
0.923 0.077 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.912 0.088 0.000
I24.8 Other forms of acute ischaemic heart disease
0.910 0.090 0.000
I71 Aortic aneurysm and dissection
0.907 0.093 0.000
I72 Other aneurysm
0.898 0.102 0.000
H53 Visual disturbances
0.897 0.103 0.000
M54.3 Sciatica
0.891 0.109 0.000
J95-J99 Other diseases of the respiratory system
0.887 0.113 0.000
I30-I52 Other forms of heart disease
0.886 0.114 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.882 0.118 0.000
J84 Other interstitial pulmonary diseases
0.881 0.119 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.877 0.123 0.000
M54.39 Sciatica (Site unspecified)
0.867 0.133 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.864 0.136 0.000
H33 Retinal detachments and breaks
0.859 0.141 0.000
A30-A49 Other bacterial diseases
0.856 0.144 0.000
J90-J94 Other diseases of pleura
0.850 0.150 0.000
B95-B98 Bacterial, viral and other infectious agents
0.849 0.151 0.000
J40-J47 Chronic lower respiratory diseases
0.849 0.151 0.000
H18.4 Corneal degeneration
0.847 0.153 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.842 0.157 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.839 0.161 0.000
M51 Other intervertebral disk disorders
0.833 0.167 0.000
I05-I09 Chronic rheumatic heart diseases
0.831 0.169 0.000
H55-H59 Other disorders of eye and adnexa
0.829 0.171 0.000
H25-H28 Disorders of lens
0.825 0.175 0.000
I35 Nonrheumatic aortic valve disorders
0.823 0.177 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.820 0.180 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.820 0.180 0.000
I77.1 Stricture of artery
0.819 0.181 0.000
J98 Other respiratory disorders
0.819 0.181 0.000
M54.1 Radiculopathy
0.818 0.182 0.000
H18.9 Disorder of cornea, unspecified
0.817 0.183 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
M54.2 Cervicalgia
0.815 0.185 0.000
I44 Atrioventricular and left bundle-branch block
0.810 0.190 0.000
H18.8 Other specified disorders of cornea
0.808 0.192 0.000
M60-M63 Disorders of muscles
0.808 0.192 0.000
I34 Nonrheumatic mitral valve disorders
0.799 0.201 0.000
H53.0 Amblyopia ex anopsia
0.796 0.204 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.795 0.205 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.793 0.207 0.000
H33.0 Retinal detachment with retinal break
0.787 0.213 0.000
H34 Retinal vascular occlusions
0.785 0.215 0.000
M79.6 Pain in limb
0.781 0.219 0.000
I77.6 Arteritis, unspecified
0.779 0.221 0.000
J45 Asthma
0.776 0.224 0.000
H53.8 Other visual disturbances
0.775 0.225 0.000
I44.1 Atrioventricular block, second degree
0.772 0.228 0.000
A49 Bacterial infection of unspecified site
0.771 0.229 0.000
I72.8 Aneurysm of other specified arteries
0.770 0.230 0.000
I34.0 Mitral (valve) insufficiency
0.764 0.236 0.000
I25.1 Atherosclerotic heart disease
0.764 0.236 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.763 0.237 0.000
H16 Keratitis
0.762 0.238 0.000
E78.4 Other hyperlipidaemia
0.756 0.244 0.000
A80-A89 Viral infections of the central nervous system
0.752 0.248 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.751 0.248 0.000
M54.22 Cervicalgia (Cervical region)
0.751 0.249 0.000
H53.1 Subjective visual disturbances
0.751 0.249 0.000
B15-B19 Viral hepatitis
0.750 0.250 0.000
M54.4 Lumbago with sciatica
0.749 0.251 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
I05 Rheumatic mitral valve diseases
0.746 0.254 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.745 0.255 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.744 0.256 0.000
M54.8 Other dorsalgia
0.744 0.256 0.000
J45.9 Asthma, unspecified
0.742 0.258 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.742 0.258 0.000
M86-M90 Other osteopathies
0.741 0.259 0.000
Q80-Q89 Other congenital malformations
0.740 0.260 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.739 0.261 0.000
E78.2 Mixed hyperlipidaemia
0.739 0.261 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.739 0.261 0.000
M54.9 Dorsalgia, unspecified
0.734 0.266 0.000
J00-J06 Acute upper respiratory infections
0.733 0.267 0.000
A49.9 Bacterial infection, unspecified
0.732 0.268 0.000
M79.66 Pain in limb (Lower leg)
0.732 0.268 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.730 0.270 0.000
I49 Other cardiac arrhythmias
0.729 0.271 0.000
J60-J70 Lung diseases due to external agents
0.726 0.274 0.000
M51.2 Other specified intervertebral disk displacement
0.726 0.274 0.000
I51 Complications and ill-defined descriptions of heart disease
0.726 0.274 0.000
J80 Adult respiratory distress syndrome
0.724 0.276 0.000
I35.1 Aortic (valve) insufficiency
0.723 0.277 0.000
J91 Pleural effusion in conditions classified elsewhere
0.721 0.279 0.000
J40 Bronchitis, not specified as acute or chronic
0.720 0.280 0.000
I70 Atherosclerosis
0.718 0.282 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.717 0.283 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
H53.9 Visual disturbance, unspecified
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
J84.8 Other specified interstitial pulmonary diseases
0.716 0.283 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
I72.4 Aneurysm of artery of lower extremity
0.711 0.288 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.710 0.290 0.000
I74 Arterial embolism and thrombosis
0.709 0.291 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.709 0.291 0.000
J90 Pleural effusion, not elsewhere classified
0.706 0.294 0.000
M79.7 Fibromyalgia
0.706 0.294 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.706 0.294 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.703 0.297 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.703 0.297 0.000
H15 Disorders of sclera
0.703 0.297 0.000
M62 Other disorders of muscle
0.703 0.297 0.000
I72.0 Aneurysm of carotid artery
0.702 0.298 0.000
H35 Other retinal disorders
0.702 0.298 0.000
H20 Iridocyclitis
0.702 0.298 0.000
H33.4 Traction detachment of retina
0.702 0.298 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
E78.8 Other disorders of lipoprotein metabolism
0.700 0.300 0.000
I25.5 Ischaemic cardiomyopathy
0.700 0.300 0.000
H17 Corneal scars and opacities
0.699 0.301 0.000
H18.7 Other corneal deformities
0.698 0.301 0.000
H18.6 Keratoconus
0.698 0.301 0.000
H18.3 Changes in corneal membranes
0.698 0.301 0.000
H18.2 Other corneal oedema
0.698 0.301 0.000
H18.1 Bullous keratopathy
0.698 0.301 0.000
H18.0 Corneal pigmentations and deposits
0.698 0.301 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.698 0.302 0.000
M40-M43 Deforming dorsopathies
0.698 0.302 0.000
H25 Senile cataract
0.697 0.303 0.000
H36 Retinal disorders in diseases classified elsewhere
0.697 0.303 0.000
E78.6 Lipoprotein deficiency
0.696 0.304 0.000
E78.3 Hyperchylomicronaemia
0.696 0.304 0.000
E78.1 Pure hyperglyceridaemia
0.696 0.304 0.000
I24.1 Dressler's syndrome
0.694 0.306 0.000
I73.8 Other specified peripheral vascular diseases
0.692 0.308 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.692 0.308 0.000
A40 Streptococcal septicaemia
0.692 0.308 0.000
M51.9 Intervertebral disk disorder, unspecified
0.689 0.311 0.000
I78 Diseases of capillaries
0.687 0.313 0.000
H53.2 Diplopia
0.685 0.315 0.000
E20-E35 Disorders of other endocrine glands
0.683 0.317 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.682 0.317 0.000
H33.1 Retinoschisis and retinal cysts
0.682 0.318 0.000
I51.7 Cardiomegaly
0.680 0.320 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
H25.9 Senile cataract, unspecified
0.679 0.321 0.000
A41 Other septicaemia
0.677 0.322 0.000
I77.8 Other specified disorders of arteries and arterioles
0.677 0.323 0.000
E73 Lactose intolerance
0.675 0.324 0.000
J98.8 Other specified respiratory disorders
0.674 0.326 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.326 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.673 0.327 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.672 0.327 0.000
H30 Chorioretinal inflammation
0.672 0.327 0.000
M54.37 Sciatica (Lumbosacral region)
0.672 0.328 0.000
M54.0 Panniculitis affecting regions of neck and back
0.671 0.329 0.000
I05.0 Mitral stenosis
0.671 0.329 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
H31 Other disorders of choroid
0.667 0.332 0.000
M54.16 Radiculopathy (Lumbar region)
0.666 0.334 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.665 0.335 0.000
I22.8 Subsequent myocardial infarction of other sites
0.665 0.335 0.000
Q00-Q07 Congenital malformations of the nervous system
0.665 0.335 0.000
B99-B99 Other infectious diseases
0.664 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.664 0.336 0.000
B65-B83 Helminthiases
0.664 0.336 0.000
B50-B64 Protozoal diseases
0.664 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.664 0.336 0.000
A75-A79 Rickettsioses
0.664 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.664 0.336 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.664 0.336 0.000
A15-A19 Tuberculosis
0.664 0.336 0.000
I45 Other conduction disorders
0.664 0.336 0.000
J44 Other chronic obstructive pulmonary disease
0.663 0.337 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.663 0.337 0.000
J86 Pyothorax
0.663 0.337 0.000
I25.3 Aneurysm of heart
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.662 0.338 0.000
I77.5 Necrosis of artery
0.661 0.338 0.000
I77.4 Coeliac artery compression syndrome
0.661 0.338 0.000
I77.3 Arterial fibromuscular dysplasia
0.661 0.338 0.000
I77.2 Rupture of artery
0.661 0.338 0.000
I77.0 Arteriovenous fistula, acquired
0.661 0.338 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.661 0.339 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.659 0.340 0.000
M54.6 Pain in thoracic spine
0.659 0.341 0.000
M79.1 Myalgia
0.658 0.342 0.000
H34.8 Other retinal vascular occlusions
0.657 0.343 0.000
H55 Nystagmus and other irregular eye movements
0.656 0.344 0.000
H04 Disorders of lachrymal system
0.654 0.346 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.651 0.349 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.651 0.349 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.650 0.349 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.650 0.349 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.650 0.349 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.650 0.349 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.650 0.350 0.000
M00-M03 Infectious arthropathies
0.648 0.351 0.000
M79.69 Pain in limb (Site unspecified)
0.648 0.352 0.000
I37 Pulmonary valve disorders
0.648 0.352 0.000
M54.19 Radiculopathy (Site unspecified)
0.647 0.353 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.647 0.353 0.000
H57 Other disorders of eye and adnexa
0.646 0.354 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.646 0.354 0.000
J42 Unspecified chronic bronchitis
0.645 0.355 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.644 0.356 0.000
E88 Other metabolic disorders
0.644 0.356 0.000
I72.9 Aneurysm of unspecified site
0.644 0.356 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.644 0.356 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.644 0.356 0.000
I72.3 Aneurysm of iliac artery
0.644 0.356 0.000
I72.2 Aneurysm of renal artery
0.644 0.356 0.000
I72.1 Aneurysm of artery of upper extremity
0.644 0.356 0.000
H53.6 Night blindness
0.643 0.357 0.000
H53.5 Colour vision deficiencies
0.643 0.357 0.000
H53.3 Other disorders of binocular vision
0.643 0.357 0.000
M50 Cervical disk disorders
0.642 0.358 0.000
M79.64 Pain in limb (Hand)
0.642 0.358 0.000
M79.67 Pain in limb (Ankle and foot)
0.640 0.360 0.000
M70.6 Trochanteric bursitis
0.640 0.360 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.639 0.361 0.000
M54.35 Sciatica (Thoracolumbar region)
0.639 0.361 0.000
M54.34 Sciatica-Thoracic
0.639 0.361 0.000
M54.33 Sciatica-Cervicothoracic
0.639 0.361 0.000
M54.32 Sciatica-Cervical
0.639 0.361 0.000
M54.31 Sciatica-Occipit-atl-axl
0.639 0.361 0.000
M54.30 Sciatica (Multiple sites in spine)
0.639 0.361 0.000
H33.5 Other retinal detachments
0.637 0.363 0.000
H21 Other disorders of iris and ciliary body
0.636 0.363 0.000
I35.9 Aortic valve disorder, unspecified
0.636 0.364 0.000
J96 Respiratory failure, not elsewhere classified
0.636 0.364 0.000
A48 Other bacterial diseases, not elsewhere classified
0.635 0.365 0.000
I52 Other heart disorders in diseases classified elsewhere
0.635 0.365 0.000
I48 Atrial fibrillation and flutter
0.635 0.365 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.635 0.365 0.000
I41 Myocarditis in diseases classified elsewhere
0.635 0.365 0.000
I40 Acute myocarditis
0.635 0.365 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.635 0.365 0.000
I32 Pericarditis in diseases classified elsewhere
0.635 0.365 0.000
J81 Pulmonary oedema
0.634 0.366 0.000
J00 Acute nasopharyngitis [common cold]
0.634 0.366 0.000
J94 Other pleural conditions
0.634 0.366 0.000
J84.0 Alveolar and parietoalveolar conditions
0.632 0.368 0.000
I36 Nonrheumatic tricuspid valve disorders
0.631 0.369 0.000
M62.8 Other specified disorders of muscle
0.628 0.372 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.627 0.373 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.627 0.373 0.000
Q85 Phakomatoses, not elsewhere classified
0.626 0.373 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.625 0.375 0.000
J98.6 Disorders of diaphragm
0.624 0.376 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.624 0.376 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.623 0.377 0.000
B00 Herpesviral [herpes simplex] infections
0.623 0.377 0.000
J93 Pneumothorax
0.622 0.378 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.621 0.379 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.620 0.380 0.000
H54 Blindness and low vision
0.620 0.380 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.620 0.380 0.000
M76 Enthesopathies of lower limb, excluding foot
0.620 0.380 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.620 0.380 0.000
I38 Endocarditis, valve unspecified
0.618 0.382 0.000
I44.3 Other and unspecified atrioventricular block
0.618 0.382 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.617 0.383 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.616 0.384 0.000
E50-E64 Other nutritional deficiencies
0.615 0.385 0.000
M79.61 Pain in limb (Shoulder region)
0.615 0.385 0.000
A44 Bartonellosis
0.614 0.386 0.000
A43 Nocardiosis
0.614 0.386 0.000
A42 Actinomycosis
0.614 0.386 0.000
A39 Meningococcal infection
0.614 0.386 0.000
A37 Whooping cough
0.614 0.386 0.000
A36 Diphtheria
0.614 0.386 0.000
A32 Listeriosis
0.614 0.386 0.000
A31 Infection due to other mycobacteria
0.614 0.386 0.000
A30 Leprosy [Hansen's disease]
0.614 0.386 0.000
A38 Scarlet fever
0.614 0.386 0.000
A35 Other tetanus
0.614 0.386 0.000
A34 Obstetrical tetanus
0.614 0.386 0.000
A33 Tetanus neonatorum
0.614 0.386 0.000
M53 Other dorsopathies, not elsewhere classified
0.612 0.387 0.000
H27 Other disorders of lens
0.610 0.390 0.000
J41 Simple and mucopurulent chronic bronchitis
0.609 0.391 0.000
A87 Viral meningitis
0.608 0.392 0.000
L20-L30 Dermatitis and eczema
0.608 0.392 0.000
M54.89 Other dorsalgia (Site unspecified)
0.606 0.394 0.000
Q82 Other congenital malformations of skin
0.605 0.395 0.000
H16.0 Corneal ulcer
0.604 0.396 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.604 0.396 0.000
Q35-Q37 Cleft lip and cleft palate
0.604 0.396 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.604 0.396 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.604 0.396 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.604 0.396 0.000
H33.2 Serous retinal detachment
0.603 0.397 0.000
M91-M94 Chondropathies
0.603 0.397 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.603 0.397 0.000
B25-B34 Other viral diseases
0.602 0.397 0.000
J95.0 Tracheostomy malfunction
0.601 0.399 0.000
I49.4 Other and unspecified premature depolarisation
0.600 0.400 0.000
M50.1 Cervical disk disorder with radiculopathy
0.600 0.400 0.000
M15-M19 Arthrosis
0.600 0.400 0.000
B17 Other acute viral hepatitis
0.599 0.401 0.000
U89 Agent resistant to other and unspecified antibiotics
0.599 0.401 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.598 0.402 0.000
I44.6 Other and unspecified fascicular block
0.597 0.402 0.000
M51.3 Other specified intervertebral disk degeneration
0.597 0.403 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.597 0.403 0.000
M51.4 Schmorl's nodes
0.597 0.403 0.000
I09 Other rheumatic heart diseases
0.596 0.404 0.000
I06 Rheumatic aortic valve diseases
0.596 0.404 0.000
M79.70 Fibromyalgia (Multiple sites)
0.596 0.404 0.000
I71.0 Dissection of aorta [any part]
0.595 0.405 0.000
B16 Acute hepatitis B
0.595 0.405 0.000
I44.2 Atrioventricular block, complete
0.594 0.406 0.000
H34.2 Other retinal artery occlusions
0.594 0.406 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.593 0.406 0.000
I07 Rheumatic tricuspid valve diseases
0.592 0.408 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.592 0.408 0.000
H26 Other cataract
0.591 0.409 0.000
M79.2 Neuralgia and neuritis, unspecified
0.590 0.410 0.000
I49.1 Atrial premature depolarisation
0.589 0.411 0.000
M79.0 Rheumatism, unspecified
0.589 0.411 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.588 0.412 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.588 0.412 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.588 0.412 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.588 0.412 0.000
I30 Acute pericarditis
0.588 0.412 0.000
M79.9 Soft tissue disorder, unspecified
0.588 0.412 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.588 0.412 0.000
M79.3 Panniculitis, unspecified
0.588 0.412 0.000
H10 Conjunctivitis
0.587 0.412 0.000
J98.9 Respiratory disorder, unspecified
0.587 0.413 0.000
J98.3 Compensatory emphysema
0.587 0.413 0.000
J98.2 Interstitial emphysema
0.587 0.413 0.000
H35.8 Other specified retinal disorders
0.587 0.413 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.587 0.413 0.000
M54.14 Radiculopathy (Thoracic region)
0.587 0.413 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.587 0.413 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.587 0.413 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.587 0.413 0.000
A49.1 Streptococcal infection, unspecified
0.584 0.416 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.584 0.416 0.000
M54.27 Cervicalgia-Lumbosacral
0.584 0.416 0.000
M54.26 Cervicalgia-Lumbar
0.584 0.416 0.000
M54.25 Cervicalgia-Thoracolumbar
0.584 0.416 0.000
M54.24 Cervicalgia-Thoracic
0.584 0.416 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.584 0.416 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.584 0.416 0.000
M54.20 Cervicalgia-Mult site
0.584 0.416 0.000
M75 Shoulder lesions
0.583 0.417 0.000
I51.0 Cardiac septal defect, acquired
0.582 0.418 0.000
M89 Other disorders of bone
0.582 0.418 0.000
Chapter VI Diseases of the nervous system
0.582 0.418 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.582 0.418 0.000
I44.5 Left posterior fascicular block
0.581 0.419 0.000
I44.4 Left anterior fascicular block
0.581 0.419 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.580 0.420 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.579 0.421 0.000
M61 Calcification and ossification of muscle
0.579 0.421 0.000
M60 Myositis
0.579 0.421 0.000
B02 Zoster [herpes zoster]
0.578 0.422 0.000
H43-H45 Disorders of vitreous body and globe
0.576 0.424 0.000
M71 Other bursopathies
0.575 0.425 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.575 0.425 0.000
L60-L75 Disorders of skin appendages
0.574 0.426 0.000
M54.12 Radiculopathy (Cervical region)
0.574 0.426 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.573 0.427 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.573 0.427 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.573 0.427 0.000
A40.9 Streptococcal septicaemia, unspecified
0.572 0.428 0.000
I33 Acute and subacute endocarditis
0.571 0.429 0.000
M87 Osteonecrosis
0.570 0.430 0.000
M70.5 Other bursitis of knee
0.570 0.430 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.569 0.430 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.569 0.431 0.000
J85 Abscess of lung and mediastinum
0.569 0.431 0.000
A86 Unspecified viral encephalitis
0.568 0.432 0.000
J46 Status asthmaticus
0.568 0.432 0.000
M90 Osteopathies in diseases classified elsewhere
0.568 0.432 0.000
M79.5 Residual foreign body in soft tissue
0.567 0.432 0.000
H35.6 Retinal haemorrhage
0.567 0.433 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.567 0.433 0.000
H35.2 Other proliferative retinopathy
0.567 0.433 0.000
I20 Angina pectoris
0.566 0.434 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.565 0.435 0.000
M41 Scoliosis
0.564 0.436 0.000
J98.4 Other disorders of lung
0.563 0.437 0.000
H34.9 Retinal vascular occlusion, unspecified
0.563 0.437 0.000
H34.1 Central retinal artery occlusion
0.563 0.437 0.000
H34.0 Transient retinal artery occlusion
0.563 0.437 0.000
I35.8 Other aortic valve disorders
0.563 0.437 0.000
E65-E68 Obesity and other hyperalimentation
0.562 0.437 0.000
Chapter V Mental and behavioural disorders
0.560 0.440 0.000
I05.9 Mitral valve disease, unspecified
0.560 0.440 0.000
M79.68 Pain in limb (Other)
0.560 0.440 0.000
M79.79 Fibromyalgia (Site unspecified)
0.560 0.440 0.000
H04.2 Epiphora
0.560 0.440 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.558 0.442 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.558 0.442 0.000
J45.8 Mixed asthma
0.556 0.444 0.000
J45.1 Nonallergic asthma
0.556 0.444 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.555 0.445 0.000
I05.1 Rheumatic mitral insufficiency
0.554 0.446 0.000
M80 Osteoporosis with pathological fracture
0.554 0.446 0.000
L28 Lichen simplex chronicus and prurigo
0.553 0.447 0.000
A49.3 Mycoplasma infection, unspecified
0.553 0.447 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.553 0.447 0.000
M65-M68 Disorders of synovium and tendon
0.552 0.448 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.549 0.451 0.000
E40-E46 Malnutrition
0.548 0.451 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.548 0.451 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.548 0.452 0.000
E26 Hyperaldosteronism
0.548 0.452 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.548 0.452 0.000
H16.9 Keratitis, unspecified
0.546 0.454 0.000
H16.8 Other keratitis
0.546 0.454 0.000
H16.4 Corneal neovascularisation
0.546 0.454 0.000
H16.3 Interstitial and deep keratitis
0.546 0.454 0.000
H16.2 Keratoconjunctivitis
0.546 0.454 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.546 0.454 0.000
L60 Nail disorders
0.546 0.454 0.000
Q60-Q64 Congenital malformations of the urinary system
0.545 0.455 0.000
I49.3 Ventricular premature depolarisation
0.545 0.455 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.545 0.455 0.000
M82 Osteoporosis in diseases classified elsewhere
0.544 0.455 0.000
A46 Erysipelas
0.544 0.456 0.000
J43 Emphysema
0.544 0.456 0.000
M70.2 Olecranon bursitis
0.544 0.456 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.543 0.457 0.000
A41.9 Septicaemia, unspecified
0.543 0.457 0.000
Q07 Other congenital malformations of nervous system
0.542 0.458 0.000
H35.7 Separation of retinal layers
0.542 0.458 0.000
M77 Other enthesopathies
0.542 0.458 0.000
H00 Hordeolum and chalazion
0.541 0.459 0.000
I45.8 Other specified conduction disorders
0.541 0.459 0.000
J86.0 Pyothorax with fistula
0.540 0.460 0.000
A88 Other viral infections of central nervous system, not elsewhere classified
0.539 0.460 0.000
A85 Other viral encephalitis, not elsewhere classified
0.539 0.460 0.000
A84 Tick-borne viral encephalitis
0.539 0.460 0.000
A83 Mosquito-borne viral encephalitis
0.539 0.460 0.000
A82 Rabies
0.539 0.460 0.000
A81 Atypical virus infections of central nervous system
0.539 0.460 0.000
A80 Acute poliomyelitis
0.539 0.460 0.000
A91 Dengue haemorrhagic fever
0.539 0.460 0.000
A90 Dengue fever [classical dengue]
0.539 0.460 0.000
A89 Unspecified viral infection of central nervous system
0.539 0.460 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.539 0.461 0.000
B06 Rubella [German measles]
0.539 0.461 0.000
B05 Measles
0.539 0.461 0.000
B01 Varicella [chickenpox]
0.539 0.461 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.539 0.461 0.000
B04 Monkeypox
0.539 0.461 0.000
B03 Smallpox
0.539 0.461 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.539 0.461 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.538 0.461 0.000
H26.4 After-cataract
0.538 0.462 0.000
B19 Unspecified viral hepatitis
0.538 0.462 0.000
B15 Acute hepatitis A
0.538 0.462 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.537 0.463 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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