TreeWAS – Variant ID: rs9926335

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E11.3 With ophthalmic complications	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.998	0.002
E11.2 With renal complications	0.993	0.007
N60-N64 Disorders of breast	0.991	0.009
N00-N08 Glomerular diseases	0.984	0.016
S20-S29 Injuries to the thorax	0.976	0.024
N61 Inflammatory disorders of breast	0.974	0.026
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.973	0.027
N20-N23 Urolithiasis	0.970	0.030
Chapter VII Diseases of the eye and adnexa	0.969	0.031
E10 Insulin-dependent diabetes mellitus	0.967	0.033
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.967	0.033
N62 Hypertrophy of breast	0.966	0.034
N08 Glomerular disorders in diseases classified elsewhere	0.963	0.037
N08.3 Glomerular disorders in diabetes mellitus	0.946	0.054
Chapter XV Pregnancy, childbirth and the puerperium	0.945	0.055
E20-E35 Disorders of other endocrine glands	0.944	0.056
Chapter VI Diseases of the nervous system	0.942	0.058
S22 Fracture of rib(s), sternum and thoracic spine	0.941	0.059
G40-G47 Episodic and paroxysmal disorders	0.938	0.062
T93 Sequelae of injuries of lower limb	0.936	0.064
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.931	0.069
N23 Unspecified renal colic	0.929	0.071
T51 Toxic effect of alcohol	0.928	0.072
H30-H36 Disorders of choroid and retina	0.924	0.076
S00-S09 Injuries to the head	0.923	0.077
G45 Transient cerebral ischaemic attacks and related syndromes	0.923	0.077
O80-O84 Delivery	0.919	0.081
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.919	0.081
H52 Disorders of refraction and accommodation	0.917	0.083
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.916	0.084
H36 Retinal disorders in diseases classified elsewhere	0.911	0.089
T51.0 Ethanol	0.909	0.091
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.906	0.094
M05-M14 Inflammatory polyarthropathies	0.904	0.096
H36.0 Diabetic retinopathy	0.901	0.099
E11.5 With peripheral circulatory complications	0.895	0.105
G47 Sleep disorders	0.895	0.105
G45.9 Transient cerebral ischaemic attack, unspecified	0.894	0.106
S22.3 Fracture of rib	0.893	0.107
E10.9 Without complications	0.891	0.109
T92 Sequelae of injuries of upper limb	0.889	0.111
M13 Other arthritis	0.888	0.112
T36-T50 Poisoning by drugs, medicaments and biological substances	0.888	0.112
N70-N77 Inflammatory diseases of female pelvic organs	0.885	0.115
Chapter IX Diseases of the circulatory system	0.882	0.118
O80 Single spontaneous delivery	0.881	0.119
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.880	0.120
M13.9 Arthritis, unspecified	0.874	0.126
I95-I99 Other and unspecified disorders of the circulatory system	0.867	0.133
E22 Hyperfunction of pituitary gland	0.865	0.135
I60-I69 Cerebrovascular diseases	0.862	0.138
H52.2 Astigmatism	0.861	0.139
M13.90 Arthritis, unspecified (Multiple sites)	0.860	0.140
S22.30 Fracture of rib (closed)	0.858	0.142
S02 Fracture of skull and facial bones	0.849	0.151
O16 Unspecified maternal hypertension	0.847	0.153
E11.4 With neurological complications	0.842	0.158
O20-O29 Other maternal disorders predominantly related to pregnancy	0.840	0.160
Chapter XX External causes of morbidity and mortality	0.839	0.161
S40-S49 Injuries to the shoulder and upper arm	0.838	0.162
I95 Hypotension	0.833	0.167
O80.0 Spontaneous vertex delivery	0.832	0.168
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.832	0.168
N21 Calculus of lower urinary tract	0.831	0.169
M13.94 Arthritis, unspecified (Hand)	0.829	0.171
S50-S59 Injuries to the elbow and forearm	0.829	0.171
S27 Injury of other and unspecified intrathoracic organs	0.826	0.173
N03 Chronic nephritic syndrome	0.826	0.174
I95.9 Hypotension, unspecified	0.825	0.175
S02.4 Fracture of malar and maxillary bones	0.825	0.175
N64 Other disorders of breast	0.821	0.179
H52.0 Hypermetropia	0.821	0.179
H52.1 Myopia	0.819	0.181
T81 Complications of procedures, not elsewhere classified	0.819	0.181
H04 Disorders of lachrymal system	0.819	0.181
T15-T19 Effects of foreign body entering through natural orifice	0.815	0.185
N75 Diseases of Bartholin's gland	0.811	0.189
E10.4 With neurological complications	0.811	0.189
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.811	0.189
S02.40 Fracture of malar and maxillary bones (closed)	0.808	0.192
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.807	0.193
O82 Single delivery by Caesarean section	0.806	0.194
S60-S69 Injuries to the wrist and hand	0.805	0.195
S05 Injury of eye and orbit	0.804	0.196
S22.5 Flail chest	0.804	0.196
T81.3 Disruption of operation wound, not elsewhere classified	0.803	0.197
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.800	0.200
G47.1 Disorders of excessive somnolence [hypersomnias]	0.799	0.201
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.798	0.202
E26 Hyperaldosteronism	0.796	0.204
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.795	0.205
I61 Intracerebral haemorrhage	0.793	0.207
H04.5 Stenosis and insufficiency of lachrymal passages	0.792	0.208
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.792	0.208
T92.1 Sequelae of fracture of arm	0.792	0.208
M10 Gout	0.791	0.209
M50-M54 Other dorsopathies	0.789	0.211
N72 Inflammatory disease of cervix uteri	0.787	0.213
T00-T07 Injuries involving multiple body regions	0.786	0.214
M86-M90 Other osteopathies	0.783	0.217
S01 Open wound of head	0.782	0.218
M13.96 Arthritis, unspecified (Lower leg)	0.780	0.220
G47.3 Sleep apnoea	0.780	0.220
E27 Other disorders of adrenal gland	0.777	0.223
T93.9 Sequelae of unspecified injury of lower limb	0.776	0.224
S62 Fracture at wrist and hand level	0.775	0.225
O20 Haemorrhage in early pregnancy	0.774	0.226
E10.2 With renal complications	0.771	0.229
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.768	0.232
E34 Other endocrine disorders	0.765	0.235
I63 Cerebral infarction	0.765	0.235
G47.8 Other sleep disorders	0.764	0.235
T84.0 Mechanical complication of internal joint prosthesis	0.764	0.236
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.762	0.238
S22.0 Fracture of thoracic vertebra	0.761	0.239
G41 Status epilepticus	0.760	0.240
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.760	0.240
T66-T78 Other and unspecified effects of external causes	0.756	0.244
G46 Vascular syndromes of brain in cerebrovascular diseases	0.755	0.245
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.753	0.246
H31 Other disorders of choroid	0.753	0.247
M51 Other intervertebral disk disorders	0.752	0.248
G00-G09 Inflammatory diseases of the central nervous system	0.751	0.249
E10.5 With peripheral circulatory complications	0.749	0.251
I67 Other cerebrovascular diseases	0.749	0.251
S06 Intracranial injury	0.749	0.251
I98 Other disorders of circulatory system in diseases classified elsewhere	0.748	0.252
T40.2 Other opioids	0.748	0.252
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.747	0.253
M45-M49 Spondylopathies	0.747	0.253
M60-M63 Disorders of muscles	0.747	0.253
N05 Unspecified nephritic syndrome	0.746	0.253
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.746	0.254
O82.9 Delivery by Caesarean section, unspecified	0.745	0.255
G80-G83 Cerebral palsy and other paralytic syndromes	0.745	0.255
S80-S89 Injuries to the knee and lower leg	0.745	0.255
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.744	0.256
H04.1 Other disorders of lachrymal gland	0.744	0.256
T93.0 Sequelae of open wound of lower limb	0.742	0.258
S01.8 Open wound of other parts of head	0.741	0.259
E10.0 With coma	0.740	0.260
T56 Toxic effect of metals	0.738	0.261
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.737	0.263
T92.2 Sequelae of fracture at wrist and hand level	0.734	0.266
T58 Toxic effect of carbon monoxide	0.732	0.268
T20-T25 Burns and corrosions of external body surface, specified by site	0.731	0.269
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.728	0.272
G44 Other headache syndromes	0.728	0.272
O80.9 Single spontaneous delivery, unspecified	0.727	0.273
M80-M85 Disorders of bone density and structure	0.725	0.275
S62.6 Fracture of other finger	0.724	0.276
T85 Complications of other internal prosthetic devices, implants and grafts	0.723	0.277
S51 Open wound of forearm	0.723	0.277
N02 Recurrent and persistent haematuria	0.721	0.279
S29 Other and unspecified injuries of thorax	0.720	0.280
S01.5 Open wound of lip and oral cavity	0.719	0.281
N08.5 Glomerular disorders in systemic connective tissue disorders	0.718	0.282
T63 Toxic effect of contact with venomous animals	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E11.8 With unspecified complications	0.717	0.283
E11.7 With multiple complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
G45.3 Amaurosis fugax	0.714	0.286
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.714	0.286
S42 Fracture of shoulder and upper arm	0.713	0.287
N75.1 Abscess of Bartholin's gland	0.713	0.287
N03.9 Unspecified	0.713	0.287
W00-W19 Falls	0.713	0.287
N70 Salpingitis and oophoritis	0.711	0.289
T84.2 Mechanical complication of internal fixation device of other bones	0.711	0.289
M10.9 Gout, unspecified	0.710	0.290
S22.1 Multiple fractures of thoracic spine	0.710	0.290
E11.1 With ketoacidosis	0.710	0.290
I99 Other and unspecified disorders of circulatory system	0.709	0.291
T59 Toxic effect of other gases, fumes and vapours	0.709	0.291
H52.7 Disorder of refraction, unspecified	0.708	0.292
N99-N99 Other disorders of the genitourinary system	0.707	0.293
N07 Hereditary nephropathy, not elsewhere classified	0.706	0.294
N06 Isolated proteinuria with specified morphological lesion	0.706	0.294
N01 Rapidly progressive nephritic syndrome	0.706	0.294
N00 Acute nephritic syndrome	0.706	0.294
S22.50 Flail chest (closed)	0.705	0.295
N20 Calculus of kidney and ureter	0.705	0.295
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.703	0.296
T93.8 Sequelae of other specified injuries of lower limb	0.703	0.297
E29 Testicular dysfunction	0.703	0.297
N64.5 Other signs and symptoms in breast	0.703	0.297
E13 Other specified diabetes mellitus	0.702	0.298
I69 Sequelae of cerebrovascular disease	0.701	0.298
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.700	0.300
S26 Injury of heart	0.700	0.300
S25 Injury of blood vessels of thorax	0.700	0.300
S24 Injury of nerves and spinal cord at thorax level	0.700	0.300
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.700	0.300
S21 Open wound of thorax	0.700	0.300
H05 Disorders of orbit	0.699	0.301
T83.1 Mechanical complication of other urinary devices and implants	0.699	0.301
T95 Sequelae of burns, corrosions and frostbite	0.697	0.302
T94 Sequelae of injuries involving multiple and unspecified body regions	0.697	0.302
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.697	0.302
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.697	0.302
G50-G59 Nerve, nerve root and plexus disorders	0.697	0.303
S20 Superficial injury of thorax	0.697	0.303
M86 Osteomyelitis	0.697	0.303
S10-S19 Injuries to the neck	0.697	0.303
N30-N39 Other diseases of urinary system	0.697	0.303
N22 Calculus of urinary tract in diseases classified elsewhere	0.695	0.304
I63.9 Cerebral infarction, unspecified	0.696	0.304
E22.1 Hyperprolactinaemia	0.694	0.305
N21.0 Calculus in bladder	0.693	0.307
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.693	0.307
E10.8 With unspecified complications	0.693	0.307
E10.7 With multiple complications	0.693	0.307
E10.6 With other specified complications	0.693	0.307
T90 Sequelae of injuries of head	0.693	0.307
T65 Toxic effect of other and unspecified substances	0.693	0.307
T62 Toxic effect of other noxious substances eaten as food	0.693	0.307
T61 Toxic effect of noxious substances eaten as seafood	0.693	0.307
T60 Toxic effect of pesticides	0.693	0.307
T57 Toxic effect of other inorganic substances	0.693	0.307
T54 Toxic effect of corrosive substances	0.693	0.307
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.693	0.307
T52 Toxic effect of organic solvents	0.693	0.307
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.693	0.307
T55 Toxic effect of soaps and detergents	0.693	0.307
N04 Nephrotic syndrome	0.693	0.307
M51.2 Other specified intervertebral disk displacement	0.691	0.309
N08.8 Glomerular disorders in other diseases classified elsewhere	0.690	0.309
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.690	0.309
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.690	0.309
N08.1 Glomerular disorders in neoplastic diseases	0.690	0.309
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.690	0.309
T93.1 Sequelae of fracture of femur	0.690	0.310
E26.0 Primary hyperaldosteronism	0.690	0.310
S62.4 Multiple fractures of metacarpal bones	0.689	0.311
N75.0 Cyst of Bartholin's gland	0.688	0.312
I61.5 Intracerebral haemorrhage, intraventricular	0.685	0.314
T87 Complications peculiar to reattachment and amputation	0.685	0.315
M00-M03 Infectious arthropathies	0.685	0.315
O20.9 Haemorrhage in early pregnancy, unspecified	0.684	0.316
S02.8 Fractures of other skull and facial bones	0.682	0.318
H43-H45 Disorders of vitreous body and globe	0.682	0.318
H46-H48 Disorders of optic nerve and visual pathways	0.680	0.320
M13.0 Polyarthritis, unspecified	0.680	0.320
M05 Seropositive rheumatoid arthritis	0.678	0.322
Chapter XXII Codes for special purposes	0.677	0.323
E35 Disorders of endocrine glands in diseases classified elsewhere	0.677	0.323
E32 Diseases of thymus	0.677	0.323
E31 Polyglandular dysfunction	0.677	0.323
E30 Disorders of puberty, not elsewhere classified	0.677	0.323
E25 Adrenogenital disorders	0.677	0.323
E20 Hypoparathyroidism	0.677	0.323
E10.3 With ophthalmic complications	0.677	0.323
H55-H59 Other disorders of eye and adnexa	0.676	0.324
S90-S99 Injuries to the ankle and foot	0.676	0.324
S05.1 Contusion of eyeball and orbital tissues	0.676	0.324
G20-G26 Extrapyramidal and movement disorders	0.675	0.325
S22.9 Fracture of bony thorax, part unspecified	0.675	0.325
S22.8 Fracture of other parts of bony thorax	0.675	0.325
O26 Maternal care for other conditions predominantly related to pregnancy	0.674	0.326
E10.1 With ketoacidosis	0.672	0.328
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.671	0.329
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.671	0.329
T93.4 Sequelae of injury of nerve of lower limb	0.671	0.329
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.671	0.329
O85-O92 Complications predominantly related to the puerperium	0.670	0.329
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.670	0.329
S42.0 Fracture of clavicle	0.670	0.330
G45.4 Transient global amnesia	0.670	0.330
E16 Other disorders of pancreatic internal secretion	0.669	0.331
S27.2 Traumatic heamopneumothorax	0.667	0.332
H51 Other disorders of binocular movement	0.667	0.333
E24 Cushing's syndrome	0.667	0.333
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.666	0.334
T51.8 Other alcohols	0.666	0.334
T51.3 Fusel oil	0.666	0.334
T51.2 2-Propanol	0.666	0.334
T51.1 Methanol	0.666	0.334
W20-W49 Exposure to inanimate mechanical forces	0.665	0.335
T39.1 4-Aminophenol derivatives	0.665	0.335
H32 Chorioretinal disorders in diseases classified elsewhere	0.663	0.337
H30 Chorioretinal inflammation	0.663	0.337
E22.0 Acromegaly and pituitary gigantism	0.662	0.337
S08 Traumatic amputation of part of head	0.661	0.338
S07 Crushing injury of head	0.661	0.338
S04 Injury of cranial nerves	0.661	0.338
S03 Dislocation, sprain and strain of joints and ligaments of head	0.661	0.338
G45.2 Multiple and bilateral precerebral artery syndromes	0.661	0.338
G45.1 Carotid artery syndrome (hemispheric)	0.661	0.338
G45.0 Vertebro-basilar artery syndrome	0.661	0.338
N21.1 Calculus in urethra	0.660	0.340
S62.3 Fracture of other metacarpal bone	0.660	0.340
H49 Paralytic strabismus	0.660	0.340
O84 Multiple delivery	0.659	0.341
O83 Other assisted single delivery	0.659	0.341
H52.6 Other disorders of refraction	0.657	0.343
H52.5 Disorders of accommodation	0.657	0.343
H52.4 Presbyopia	0.657	0.343
G83 Other paralytic syndromes	0.656	0.344
M45 Ankylosing spondylitis	0.656	0.344
X10-X19 Contact with heat and hot substances	0.656	0.344
T79-T79 Certain early complications of trauma	0.654	0.346
S05.8 Other injuries of eye and orbit	0.654	0.346
O94-O99 Other obstetric conditions, not elsewhere classified	0.654	0.346
T98 Sequelae of other and unspecified effects of external causes	0.653	0.346
M13.97 Arthritis, unspecified (Ankle and foot)	0.653	0.347
H36.8 Other retinal disorders in diseases classified elsewhere	0.653	0.347
Q50-Q56 Congenital malformations of genital organs	0.652	0.348
T18 Foreign body in alimentary tract	0.652	0.348
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.652	0.348
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.652	0.348
H34 Retinal vascular occlusions	0.652	0.348
O80.8 Other single spontaneous delivery	0.650	0.350
O15 Eclampsia	0.650	0.350
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.650	0.350
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.650	0.350
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.650	0.350
N10-N16 Renal tubulo-interstitial diseases	0.648	0.352
E27.2 Addisonian crisis	0.648	0.352
M12 Other specific arthropathies	0.648	0.352
M09 Juvenile arthritis in diseases classified elsewhere	0.648	0.352
M08 Juvenile arthritis	0.648	0.352
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.648	0.352
S82 Fracture of lower leg, including ankle	0.647	0.353
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.646	0.354
S41 Open wound of shoulder and upper arm	0.646	0.354
M14 Arthropathies in other diseases classified elsewhere	0.645	0.355
E50-E64 Other nutritional deficiencies	0.645	0.355
S62.60 Fracture of other finger (closed)	0.645	0.355
N64.1 Fat necrosis of breast	0.644	0.355
O20.0 Threatened abortion	0.644	0.356
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.644	0.356
E11.0 With coma	0.644	0.356
M40-M43 Deforming dorsopathies	0.644	0.356
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.642	0.357
M51.8 Other specified intervertebral disk disorders	0.642	0.358
I67.8 Other specified cerebrovascular diseases	0.642	0.358
G47.4 Narcolepsy and cataplexy	0.641	0.359
G47.2 Disorders of the sleep-wake schedule	0.641	0.359
S22.31 Fracture of rib (open)	0.640	0.360
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.640	0.360
V10-V19 Pedal cyclist injured in transport accident	0.640	0.360
S42.00 Fracture of clavicle (closed)	0.639	0.361
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.639	0.361
T92.8 Sequelae of other specified injuries of upper limb	0.637	0.362
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.637	0.362
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.637	0.362
T92.4 Sequelae of injury of nerve of upper limb	0.637	0.362
M13.8 Other specified arthritis	0.636	0.364
M13.1 Monoarthritis, not elsewhere classified	0.636	0.364
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.636	0.364
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.636	0.364
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.636	0.364
T46 Poisoning by agents primarily affecting the cardiovascular system	0.636	0.364
T41 Poisoning by anaesthetics and therapeutic gases	0.636	0.364
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.636	0.364
T36 Poisoning by systemic antibiotics	0.636	0.364
S27.0 Traumatic pneumothorax	0.636	0.364
E23 Hypofunction and other disorders of pituitary gland	0.635	0.364
M10.97 Gout, unspecified (Ankle and foot)	0.635	0.365
M86.9 Osteomyelitis, unspecified	0.635	0.365
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.634	0.365
T92.0 Sequelae of open wound of upper limb	0.634	0.366
G41.9 Status epilepticus, unspecified	0.633	0.367
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.633	0.367
T16 Foreign body in ear	0.633	0.367
I00-I02 Acute rheumatic fever	0.632	0.367
T92.9 Sequelae of unspecified injury of upper limb	0.632	0.367
T02 Fractures involving multiple body regions	0.632	0.368
S22.00 Fracture of thoracic vertebra (closed)	0.632	0.368
N20.2 Calculus of kidney with calculus of ureter	0.632	0.368
H18 Other disorders of cornea	0.632	0.368
O80.1 Spontaneous breech delivery	0.631	0.368
H04.3 Acute and unspecified inflammation of lachrymal passages	0.631	0.369
S02.6 Fracture of mandible	0.631	0.369
S50 Superficial injury of forearm	0.631	0.369
V20-V29 Motorcycle rider injured in transport accident	0.630	0.370
Y00-Y09 Assault	0.630	0.370
S62.61 Fracture of other finger (open)	0.630	0.370
O81 Single delivery by forceps and vacuum extractor	0.630	0.370
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.629	0.371
I70-I79 Diseases of arteries, arterioles and capillaries	0.628	0.372
S62.40 Multiple fractures of metacarpal bones (closed)	0.628	0.372
M13.92 Arthritis, unspecified (Upper arm)	0.626	0.374
M13.91 Arthritis, unspecified (Shoulder region)	0.625	0.375
O14.0 Moderate preeclampsia	0.625	0.375
W19 Unspecified fall	0.625	0.375
S60 Superficial injury of wrist and hand	0.625	0.375
G46.4 Cerebellar stroke syndrome	0.624	0.376
S22.2 Fracture of sternum	0.624	0.376
I98.2 Oesophageal varices in diseases classified elsewhere	0.624	0.376
M62 Other disorders of muscle	0.623	0.377
H31.1 Choroidal degeneration	0.621	0.379
S51.9 Open wound of forearm, part unspecified	0.621	0.379
Q80-Q89 Other congenital malformations	0.621	0.379
E22.9 Hyperfunction of pituitary gland, unspecified	0.620	0.379
E22.8 Other hyperfunction of pituitary gland	0.620	0.379
O24 Diabetes mellitus in pregnancy	0.620	0.380
S06.5 Traumatic subdural haemorrhage	0.620	0.380
T68 Hypothermia	0.620	0.380
N31.8 Other neuromuscular dysfunction of bladder	0.620	0.380
M11 Other crystal arthropathies	0.619	0.381
H17 Corneal scars and opacities	0.619	0.381
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.618	0.381
I68 Cerebrovascular disorders in diseases classified elsewhere	0.618	0.382
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.618	0.382
X20-X29 Contact with venomous animals and plants	0.618	0.382
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.618	0.382
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.618	0.382
T88 Other complications of surgical and medical care, not elsewhere classified	0.618	0.382
S27.3 Other injuries of lung	0.617	0.383
M84 Disorders of continuity of bone	0.616	0.384
S46 Injury of muscle and tendon at shoulder and upper arm level	0.616	0.384
V40-V49 Car occupant injured in transport accident	0.614	0.386
E40-E46 Malnutrition	0.614	0.386
S27.1 Traumatic haemothorax	0.611	0.389
M89 Other disorders of bone	0.611	0.389
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.611	0.389
G44.0 Cluster headache syndrome	0.610	0.390
X60-X84 Intentional self-harm	0.610	0.390
Y60-Y69 Misadventures to patients during surgical and medical care	0.610	0.390
E11.6 With other specified complications	0.609	0.391
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.609	0.391
S02.9 Fracture of skull and facial bones, part unspecified	0.609	0.391
S02.7 Multiple fractures involving skull and facial bones	0.609	0.391
N64.4 Mastodynia	0.608	0.392
M07 Psoriatic and enteropathic arthropathies	0.608	0.392
S80 Superficial injury of lower leg	0.608	0.392
W50-W64 Exposure to animate mechanical forces	0.607	0.393
I62 Other nontraumatic intracranial haemorrhage	0.607	0.393
G06 Intracranial and intraspinal abscess and granuloma	0.606	0.394
E34.9 Endocrine disorder, unspecified	0.606	0.394
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.606	0.394
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.605	0.395
S49 Other and unspecified injuries of shoulder and upper arm	0.604	0.396
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.604	0.396
W06 Fall involving bed	0.603	0.396
O29 Complications of anaesthesia during pregnancy	0.602	0.398
O28 Abnormal findings on antenatal screening of mother	0.602	0.398
O22 Venous complications in pregnancy	0.602	0.398
O25 Malnutrition in pregnancy	0.602	0.398
H16 Keratitis	0.602	0.398
G09 Sequelae of inflammatory diseases of central nervous system	0.602	0.398
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.602	0.398
Y35-Y36 Legal intervention and operations of war	0.601	0.399
Y10-Y34 Event of undetermined intent	0.601	0.399
X85-X99 Assault	0.601	0.399
X58-X59 Accidental exposure to other and unspecified factors	0.601	0.399
X30-X39 Exposure to forces of nature	0.601	0.399
X00-X09 Exposure to smoke, fire and flames	0.601	0.399
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.601	0.399
W75-W84 Other accidental threats to breathing	0.601	0.399
W65-W74 Accidental drowning and submersion	0.601	0.399
V98-V99 Other and unspecified transport accidents	0.601	0.399
V95-V97 Air and space transport accidents	0.601	0.399
V90-V94 Water transport accidents	0.601	0.399
V70-V79 Bus occupant injured in transport accident	0.601	0.399
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.601	0.399
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.601	0.399
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.601	0.399
V01-V09 Pedestrian injured in transport accident	0.601	0.399
S48 Traumatic amputation of shoulder and upper arm	0.601	0.399
S45 Injury of blood vessels at shoulder and upper arm level	0.601	0.399
S44 Injury of nerves at shoulder and upper arm level	0.601	0.399
S47 Crushing injury of shoulder and upper arm	0.601	0.399
S32 Fracture of lumbar spine and pelvis	0.601	0.399
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.599	0.401
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.599	0.401
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.599	0.401
S01.3 Open wound of ear	0.599	0.401
E27.4 Other and unspecified adrenocortical insufficiency	0.598	0.402
S06.9 Intracranial injury, unspecified	0.598	0.402
S56 Injury of muscle and tendon at forearm level	0.597	0.403
I95.8 Other hypotension	0.597	0.403
I95.0 Idiopathic hypotension	0.597	0.403
H03 Disorders of eyelid in diseases classified elsewhere	0.596	0.403
N21.9 Calculus of lower urinary tract, unspecified	0.596	0.404
N21.8 Other lower urinary tract calculus	0.596	0.404
T42.0 Hydantoin derivatives	0.595	0.405
S59 Other and unspecified injuries of forearm	0.594	0.406
S58 Traumatic amputation of forearm	0.594	0.406
S57 Crushing injury of forearm	0.594	0.406
S55 Injury of blood vessels at forearm level	0.594	0.406
S54 Injury of nerves at forearm level	0.594	0.406
G30-G32 Other degenerative diseases of the nervous system	0.594	0.406
M45.X9 Ankylosing spondylitis (Site unspecified)	0.593	0.407
M91-M94 Chondropathies	0.593	0.407
I69.3 Sequelae of cerebral infarction	0.593	0.407
S27.9 Injury of unspecified intrathoracic organ	0.593	0.407
S27.8 Injury of other specified intrathoracic organs	0.593	0.407
S27.7 Multiple injuries of intrathoracic organs	0.593	0.407

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations