TreeWAS – Variant ID: rs7185320

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
R30-R39 Symptoms and signs involving the urinary system	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter XXI Factors influencing health status and contact with health services	0.995	0.005
Z40-Z54 Persons encountering health services for specific procedures and health care	0.992	0.008
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.990	0.010
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.989	0.011
Chapter VIII Diseases of the ear and mastoid process	0.989	0.011
M50-M54 Other dorsopathies	0.987	0.013
R35 Polyuria	0.982	0.018
M51 Other intervertebral disk disorders	0.982	0.018
Z50 Care involving use of rehabilitation procedures	0.976	0.024
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.967	0.033
O80-O84 Delivery	0.964	0.036
O00-O08 Pregnancy with abortive outcome	0.963	0.037
M80-M85 Disorders of bone density and structure	0.960	0.040
R31 Unspecified haematuria	0.958	0.042
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.956	0.044
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.955	0.045
M51.2 Other specified intervertebral disk displacement	0.952	0.048
H60-H62 Diseases of external ear	0.952	0.048
Chapter VII Diseases of the eye and adnexa	0.949	0.051
H90-H95 Other disorders of ear	0.945	0.055
Chapter XX External causes of morbidity and mortality	0.945	0.055
Z43 Attention to artificial openings	0.939	0.061
O80 Single spontaneous delivery	0.938	0.062
R30 Pain associated with micturition	0.938	0.062
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.936	0.064
Z42 Follow-up care involving plastic surgery	0.934	0.066
O80.0 Spontaneous vertex delivery	0.930	0.070
M86-M90 Other osteopathies	0.921	0.079
H61 Other disorders of external ear	0.921	0.079
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.915	0.085
H30-H36 Disorders of choroid and retina	0.907	0.093
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.903	0.097
R32 Unspecified urinary incontinence	0.899	0.101
R21 Rash and other nonspecific skin eruption	0.897	0.103
S60-S69 Injuries to the wrist and hand	0.897	0.103
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.896	0.104
O20-O29 Other maternal disorders predominantly related to pregnancy	0.895	0.105
M81 Osteoporosis without pathological fracture	0.892	0.108
M54 Dorsalgia	0.889	0.111
O03 Spontaneous abortion	0.884	0.116
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.883	0.117
H33 Retinal detachments and breaks	0.880	0.120
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.879	0.121
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.878	0.122
O32 Maternal care for known or suspected malpresentation of foetus	0.874	0.126
R20 Disturbances of skin sensation	0.873	0.127
Z42.1 Follow-up care involving plastic surgery of breast	0.873	0.127
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.871	0.129
Chapter V Mental and behavioural disorders	0.871	0.129
Z50.8 Care involving use of rehabilitation procedures	0.870	0.130
H91 Other hearing loss	0.870	0.130
Z40 Prophylactic surgery	0.867	0.133
H61.0 Perichondritis of external ear	0.866	0.134
Chapter X Diseases of the respiratory system	0.865	0.135
M51.8 Other specified intervertebral disk disorders	0.853	0.147
H33.3 Retinal breaks without detachment	0.852	0.148
R41 Other symptoms and signs involving cognitive functions and awareness	0.851	0.149
R81 Glycosuria	0.851	0.149
S10-S19 Injuries to the neck	0.848	0.152
Z49 Care involving dialysis	0.845	0.155
R30.0 Dysuria	0.845	0.155
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.844	0.156
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.842	0.158
M84 Disorders of continuity of bone	0.840	0.160
F00-F09 Organic, including symptomatic, mental disorders	0.839	0.161
Z50.5 Speech therapy	0.839	0.161
S50-S59 Injuries to the elbow and forearm	0.837	0.163
J90-J94 Other diseases of pleura	0.831	0.169
R80 Isolated proteinuria	0.829	0.171
O03.9 Complete or unspecified, without complication	0.828	0.172
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.827	0.172
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.827	0.173
K50-K52 Noninfective enteritis and colitis	0.825	0.175
J92 Pleural plaque	0.824	0.176
O00 Ectopic pregnancy	0.823	0.177
Chapter XI Diseases of the digestive system	0.823	0.177
V10-V19 Pedal cyclist injured in transport accident	0.823	0.177
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.820	0.180
K51 Ulcerative colitis	0.820	0.180
Z43.1 Attention to gastrostomy	0.816	0.184
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.815	0.185
Z50.2 Alcohol rehabilitation	0.815	0.185
S61 Open wound of wrist and hand	0.813	0.187
R36 Urethral discharge	0.813	0.187
R30.9 Painful micturition, unspecified	0.811	0.189
K52 Other non-infective gastro-enteritis and colitis	0.809	0.191
O32.1 Maternal care for breech presentation	0.808	0.192
M87 Osteonecrosis	0.808	0.192
M81.9 Osteoporosis, unspecified	0.806	0.194
H61.3 Acquired stenosis of external ear canal	0.802	0.198
S32 Fracture of lumbar spine and pelvis	0.802	0.198
H43-H45 Disorders of vitreous body and globe	0.801	0.199
Z43.2 Attention to ileostomy	0.801	0.199
O46 Antepartum haemorrhage, not elsewhere classified	0.800	0.200
O20 Haemorrhage in early pregnancy	0.798	0.202
R20.8 Other and unspecified disturbances of skin sensation	0.797	0.203
O43 Placental disorders	0.797	0.203
H90 Conductive and sensorineural hearing loss	0.797	0.203
Chapter VI Diseases of the nervous system	0.796	0.204
R41.0 Disorientation, unspecified	0.796	0.204
Z54 Convalescence	0.795	0.205
Z34 Supervision of normal pregnancy	0.794	0.206
W00-W19 Falls	0.794	0.206
M85 Other disorders of bone density and structure	0.793	0.207
M86 Osteomyelitis	0.790	0.210
J92.0 Pleural plaque with presence of asbestos	0.790	0.210
W50-W64 Exposure to animate mechanical forces	0.789	0.211
H91.9 Hearing loss, unspecified	0.786	0.214
R34 Anuria and oliguria	0.784	0.216
O02 Other abnormal products of conception	0.784	0.216
J92.9 Pleural plaque without asbestos	0.783	0.217
R82 Other abnormal findings in urine	0.783	0.217
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.782	0.218
H93 Other disorders of ear, not elsewhere classified	0.782	0.218
M54.4 Lumbago with sciatica	0.780	0.220
O81 Single delivery by forceps and vacuum extractor	0.780	0.220
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.780	0.220
O41 Other disorders of amniotic fluid and membranes	0.779	0.221
Z70-Z76 Persons encountering health services in other circumstances	0.777	0.223
Z43.0 Attention to tracheostomy	0.776	0.224
O85-O92 Complications predominantly related to the puerperium	0.774	0.226
K51.9 Ulcerative colitis, unspecified	0.770	0.230
R41.3 Other amnesia	0.768	0.232
Chapter XIV Diseases of the genitourinary system	0.767	0.233
F00 Dementia in Alzheimer's disease	0.767	0.233
Z42.0 Follow-up care involving plastic surgery of head and neck	0.767	0.233
T36-T50 Poisoning by drugs, medicaments and biological substances	0.764	0.236
T79-T79 Certain early complications of trauma	0.761	0.239
Z45 Adjustment and management of implanted device	0.759	0.241
J40-J47 Chronic lower respiratory diseases	0.759	0.241
F03 Unspecified dementia	0.758	0.242
N40 Hyperplasia of prostate	0.758	0.242
Z57 Occupational exposure to risk-factors	0.758	0.242
M84.1 Nonunion of fracture [pseudarthrosis]	0.758	0.242
T20-T25 Burns and corrosions of external body surface, specified by site	0.757	0.243
S61.9 Open wound of wrist and hand, part unspecified	0.757	0.243
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.757	0.243
T87 Complications peculiar to reattachment and amputation	0.755	0.245
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.754	0.246
M00-M03 Infectious arthropathies	0.753	0.247
H33.5 Other retinal detachments	0.753	0.247
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.750	0.250
S90-S99 Injuries to the ankle and foot	0.748	0.252
H46-H48 Disorders of optic nerve and visual pathways	0.747	0.253
N40-N51 Diseases of male genital organs	0.747	0.253
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.742	0.258
H10-H13 Disorders of conjunctiva	0.741	0.259
X20-X29 Contact with venomous animals and plants	0.740	0.260
T82.0 Mechanical complication of heart valve prosthesis	0.739	0.261
Z44 Fitting and adjustment of external prosthetic device	0.739	0.261
R29.6 Tendency to fall, not elsewhere classified	0.738	0.262
M81.99 Osteoporosis, unspecified (Site unspecified)	0.737	0.263
J47 Bronchiectasis	0.737	0.263
K90-K93 Other diseases of the digestive system	0.736	0.264
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.736	0.264
V18 Pedal cyclist injured in noncollision transport accident	0.735	0.265
K65-K67 Diseases of peritoneum	0.735	0.265
T15-T19 Effects of foreign body entering through natural orifice	0.735	0.265
Q80-Q89 Other congenital malformations	0.735	0.265
T00-T07 Injuries involving multiple body regions	0.733	0.266
K51.2 Ulcerative (chronic) proctitis	0.733	0.267
S68 Traumatic amputation of wrist and hand	0.733	0.267
M45-M49 Spondylopathies	0.733	0.267
M81.4 Drug-induced osteoporosis	0.732	0.268
K51.8 Other ulcerative colitis	0.732	0.268
W20-W49 Exposure to inanimate mechanical forces	0.732	0.268
Z49.1 Extracorporeal dialysis	0.731	0.269
H61.8 Other specified disorders of external ear	0.730	0.270
S32.4 Fracture of acetabulum	0.730	0.270
S66 Injury of muscle and tendon at wrist and hand level	0.730	0.270
R73 Elevated blood glucose level	0.729	0.271
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.729	0.271
O60-O75 Complications of labour and delivery	0.729	0.271
H33.1 Retinoschisis and retinal cysts	0.728	0.272
S14 Injury of nerves and spinal cord at neck level	0.728	0.272
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.727	0.273
G90-G99 Other disorders of the nervous system	0.725	0.275
K52.8 Other specified non-infective gastro-enteritis and colitis	0.725	0.275
S70-S79 Injuries to the hip and thigh	0.723	0.277
Z41 Procedures for purposes other than remedying health state	0.721	0.279
M53 Other dorsopathies, not elsewhere classified	0.719	0.280
Z60 Problems related to social environment	0.719	0.281
M60-M63 Disorders of muscles	0.718	0.281
H60 Otitis externa	0.718	0.282
Z52 Donors of organs and tissues	0.717	0.283
T82.3 Mechanical complication of other vascular grafts	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
F00.9 Dementia in Alzheimer's disease, unspecified	0.716	0.284
S40-S49 Injuries to the shoulder and upper arm	0.713	0.287
R25 Abnormal involuntary movements	0.712	0.288
X10-X19 Contact with heat and hot substances	0.712	0.288
H43 Disorders of vitreous body	0.712	0.288
J80-J84 Other respiratory diseases principally affecting the interstitium	0.712	0.288
R72 Abnormality of white blood cells, not elsewhere classified	0.711	0.289
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.711	0.289
V40-V49 Car occupant injured in transport accident	0.711	0.289
H91.8 Other specified hearing loss	0.711	0.289
T33-T35 Frostbite	0.709	0.291
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.291
Z46 Fitting and adjustment of other devices	0.708	0.292
X40-X49 Accidental poisoning by and exposure to noxious substances	0.707	0.293
S69 Other and unspecified injuries of wrist and hand	0.707	0.293
O23 Infections of genito-urinary tract in pregnancy	0.705	0.295
Z34.9 Supervision of normal pregnancy, unspecified	0.704	0.296
X60-X84 Intentional self-harm	0.704	0.296
M51.3 Other specified intervertebral disk degeneration	0.704	0.296
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.704	0.296
M51.4 Schmorl's nodes	0.704	0.296
M87.9 Osteonecrosis, unspecified	0.703	0.296
O46.9 Antepartum haemorrhage, unspecified	0.703	0.297
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.703	0.297
K65 Peritonitis	0.700	0.300
Z34.0 Supervision of normal first pregnancy	0.700	0.300
Z50.6 Orthoptic training	0.700	0.300
Z50.3 Drug rehabilitation	0.700	0.300
T91 Sequelae of injuries of neck and trunk	0.700	0.300
O30 Multiple gestation	0.699	0.301
O04 Medical abortion	0.697	0.303
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.692	0.308
O20.0 Threatened abortion	0.691	0.309
J93 Pneumothorax	0.691	0.309
W17 Other fall from one level to another	0.691	0.309
O84 Multiple delivery	0.691	0.309
O83 Other assisted single delivery	0.691	0.309
O08 Complications following abortion and ectopic and molar pregnancy	0.690	0.310
O07 Failed attempted abortion	0.690	0.310
O06 Unspecified abortion	0.690	0.310
O05 Other abortion	0.690	0.310
O01 Hydatidiform mole	0.690	0.310
T86 Failure and rejection of transplanted organs and tissues	0.690	0.310
Z43.6 Attention to other artificial openings of urinary tract	0.690	0.310
S31 Open wound of abdomen, lower back and pelvis	0.690	0.310
Q38-Q45 Other congenital malformations of the digestive system	0.689	0.311
H33.4 Traction detachment of retina	0.688	0.312
H34 Retinal vascular occlusions	0.688	0.312
M83 Adult osteomalacia	0.688	0.312
M82 Osteoporosis in diseases classified elsewhere	0.688	0.312
O26 Maternal care for other conditions predominantly related to pregnancy	0.687	0.313
M89 Other disorders of bone	0.686	0.314
O00.1 Tubal pregnancy	0.686	0.314
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.685	0.315
M54.5 Low back pain	0.684	0.316
Q60-Q64 Congenital malformations of the urinary system	0.684	0.316
M88 Paget's disease of bone [osteitis deformans]	0.684	0.316
R20.2 Paraesthesia of skin	0.683	0.317
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.682	0.318
H62 Disorders of external ear in diseases classified elsewhere	0.682	0.318
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.682	0.318
Z56 Problems related to employment and unemployment	0.680	0.319
O94-O99 Other obstetric conditions, not elsewhere classified	0.680	0.319
Z40.8 Other prophylactic surgery	0.680	0.320
Z43.3 Attention to colostomy	0.680	0.320
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.680	0.320
S32.40 Fracture of acetabulum (closed)	0.679	0.321
S65 Injury of blood vessels at wrist and hand level	0.678	0.322
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.678	0.322
W55 Bitten or struck by other mammals	0.678	0.322
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.677	0.322
H94 Other disorders of ear in diseases classified elsewhere	0.677	0.322
Y35-Y36 Legal intervention and operations of war	0.677	0.323
Y10-Y34 Event of undetermined intent	0.677	0.323
Y00-Y09 Assault	0.677	0.323
X85-X99 Assault	0.677	0.323
X58-X59 Accidental exposure to other and unspecified factors	0.677	0.323
X30-X39 Exposure to forces of nature	0.677	0.323
X00-X09 Exposure to smoke, fire and flames	0.677	0.323
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.677	0.323
W75-W84 Other accidental threats to breathing	0.677	0.323
W65-W74 Accidental drowning and submersion	0.677	0.323
V98-V99 Other and unspecified transport accidents	0.677	0.323
V95-V97 Air and space transport accidents	0.677	0.323
V90-V94 Water transport accidents	0.677	0.323
V70-V79 Bus occupant injured in transport accident	0.677	0.323
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.677	0.323
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.677	0.323
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.677	0.323
V01-V09 Pedestrian injured in transport accident	0.677	0.323
R39 Other symptoms and signs involving the urinary system	0.677	0.323
Q00-Q07 Congenital malformations of the nervous system	0.675	0.325
V18.0 Driver injured in nontraffic accident	0.675	0.325
H65-H75 Diseases of middle ear and mastoid	0.675	0.325
Z63 Other problems related to primary support group, including family circumstances	0.674	0.326
J86 Pyothorax	0.674	0.326
M50 Cervical disk disorders	0.674	0.326
Z43.9 Attention to unspecified artificial opening	0.674	0.326
Z43.8 Attention to other artificial openings	0.674	0.326
Z43.7 Attention to artificial vagina	0.674	0.326
O80.8 Other single spontaneous delivery	0.673	0.327
O80.1 Spontaneous breech delivery	0.673	0.327
O42 Premature rupture of membranes	0.673	0.327
R30.1 Vesical tenesmus	0.672	0.327
Z43.5 Attention to cyctostomy	0.672	0.328
M54.47 Lumbago with sciatica (Lumbosacral region)	0.672	0.328
S56 Injury of muscle and tendon at forearm level	0.672	0.328
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.671	0.329
R77 Other abnormalities of plasma proteins	0.671	0.329
H31 Other disorders of choroid	0.671	0.329
O45 Premature separation of placenta [abruptio placentae]	0.671	0.329
O33 Maternal care for known or suspected disproportion	0.671	0.329
O31 Complications specific to multiple gestation	0.671	0.329
K65.9 Peritonitis, unspecified	0.671	0.329
Z42.9 Follow-up care involving plastic surgery, unspecified	0.669	0.331
Z42.8 Follow-up care involving plastic surgery of other body part	0.669	0.331
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.669	0.331
K52.1 Toxic gastro-enteritis and colitis	0.669	0.331
N42 Other disorders of prostate	0.669	0.331
H61.9 Disorder of external ear, unspecified	0.668	0.332
M81.2 Osteoporosis of disuse	0.668	0.332
N70-N77 Inflammatory diseases of female pelvic organs	0.667	0.333
O41.0 Oligohydramnios	0.667	0.333
Z43.4 Attention to other artificial openings of digestive tract	0.667	0.333
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.666	0.334
H18 Other disorders of cornea	0.665	0.335
Z57.2 Occupational exposure to dust	0.664	0.336
K51.5 Mucosal proctocolitis	0.663	0.337
S54 Injury of nerves at forearm level	0.662	0.338
O02.1 Missed abortion	0.662	0.338
M40-M43 Deforming dorsopathies	0.662	0.338
M86.6 Other chronic osteomyelitis	0.661	0.339
T51 Toxic effect of alcohol	0.660	0.339
H61.1 Non-infective disorders of pinna	0.660	0.340
S61.1 Open wound of finger(s) with damage to nail	0.660	0.340
M54.2 Cervicalgia	0.659	0.341
N00-N08 Glomerular diseases	0.658	0.342
R47-R49 Symptoms and signs involving speech and voice	0.658	0.342
H53-H54 Visual disturbances and blindness	0.657	0.343
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.657	0.343
O44 Placenta praevia	0.656	0.344
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.655	0.344
H21 Other disorders of iris and ciliary body	0.655	0.345
H90.2 Conductive hearing loss, unspecified	0.655	0.345
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.654	0.346
O00.9 Ectopic pregnancy, unspecified	0.654	0.346
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.654	0.346
O32.0 Maternal care for unstable lie	0.654	0.346
X50-X57 Overexertion, travel and privation	0.653	0.347
M54.3 Sciatica	0.652	0.348
V80-V89 Other land transport accidents	0.652	0.348
O43.8 Other placental disorders	0.651	0.349
R74 Abnormal serum enzyme levels	0.651	0.349
T88 Other complications of surgical and medical care, not elsewhere classified	0.651	0.349
H32 Chorioretinal disorders in diseases classified elsewhere	0.650	0.349
H30 Chorioretinal inflammation	0.650	0.349
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.650	0.349
H36 Retinal disorders in diseases classified elsewhere	0.649	0.351
Z22 Carrier of infectious disease	0.649	0.351
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.649	0.351
O81.4 Vacuum extractor delivery	0.648	0.352
H93.9 Disorder of ear, unspecified	0.648	0.352
Z34.8 Supervision of other normal pregnancy	0.648	0.352
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.648	0.352
Q35-Q37 Cleft lip and cleft palate	0.648	0.352
Q30-Q34 Congenital malformations of the respiratory system	0.648	0.352
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.647	0.353
K92 Other diseases of digestive system	0.646	0.354
H33.0 Retinal detachment with retinal break	0.646	0.354
O28 Abnormal findings on antenatal screening of mother	0.646	0.354
O24 Diabetes mellitus in pregnancy	0.646	0.354
H80-H83 Diseases of inner ear	0.646	0.354
H01 Other inflammation of eyelid	0.646	0.354
M54.6 Pain in thoracic spine	0.645	0.355
M90 Osteopathies in diseases classified elsewhere	0.645	0.355
M54.9 Dorsalgia, unspecified	0.644	0.356
Q50-Q56 Congenital malformations of genital organs	0.644	0.356
O43.1 Malformation of placenta	0.644	0.356
M54.1 Radiculopathy	0.643	0.357
Z65 Problems related to other psychosocial circumstances	0.642	0.358
Z64 Problems related to certain psychosocial circumstances	0.642	0.358
Z62 Other problems related to upbringing	0.642	0.358
Z61 Problems related to negative life events in childhood	0.642	0.358
Z59 Problems related to housing and economic circumstances	0.642	0.358
Z58 Problems related to physical environment	0.642	0.358
Z55 Problems related to education and literacy	0.642	0.358
O29 Complications of anaesthesia during pregnancy	0.642	0.358
O22 Venous complications in pregnancy	0.642	0.358
O25 Malnutrition in pregnancy	0.642	0.358
F30-F39 Mood [affective] disorders	0.642	0.358
F80-F89 Disorders of psychological development	0.641	0.359
G99 Other disorders of nervous system in diseases classified elsewhere	0.641	0.359
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.640	0.360
S60 Superficial injury of wrist and hand	0.640	0.360
M81.8 Other osteoporosis	0.640	0.360
M81.6 Localised osteoporosis [Lequesne]	0.640	0.360
M81.5 Idiopathic osteoporosis	0.640	0.360
M81.3 Postsurgical malabsorption osteoporosis	0.640	0.360
M81.1 Postoophorectomy osteoporosis	0.640	0.360
M81.0 Postmenopausal osteoporosis	0.640	0.360
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.639	0.361
S92 Fracture of foot, except ankle	0.638	0.362
T87.4 Infection of amputation stump	0.638	0.362
S32.7 Multiple fractures of lumbar spine and pelvis	0.638	0.362
S52 Fracture of forearm	0.638	0.362
M54.8 Other dorsalgia	0.637	0.362
M54.0 Panniculitis affecting regions of neck and back	0.637	0.362
Z54.4 Convalescence following treatment of fracture	0.637	0.363
M80 Osteoporosis with pathological fracture	0.637	0.363
O35 Maternal care for known or suspected foetal abnormality and damage	0.636	0.364
M81.98 Osteoporosis, unspecified (Other)	0.636	0.364
O75 Other complications of labour and delivery, not elsewhere classified	0.636	0.364
O71 Other obstetric trauma	0.636	0.364
N76 Other inflammation of vagina and vulva	0.636	0.364
K51.0 Ulcerative (chronic) enterocolitis	0.634	0.366
O03.8 Complete or unspecified, with other and unspecified complications	0.633	0.366
O03.7 Complete or unspecified, complicated by embolism	0.633	0.366
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.633	0.366
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.633	0.366
O03.3 Incomplete, with other and unspecified complications	0.633	0.366
O03.2 Incomplete, complicated by embolism	0.633	0.366
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.633	0.366
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.633	0.366
M85.8 Other specified disorders of bone density and structure	0.633	0.366
R76 Other abnormal immunological findings in serum	0.633	0.367
Z76 Persons encountering health services in other circumstances	0.633	0.367
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.632	0.368
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.632	0.368
J44 Other chronic obstructive pulmonary disease	0.632	0.368
R82.8 Abnormal findings on cytological and histological examination of urine	0.632	0.368
Z37 Outcome of delivery	0.632	0.368
S32.1 Fracture of sacrum	0.631	0.369
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.631	0.369
Z31 Procreative management	0.631	0.369
R78 Findings of drugs and other substances, not normally found in blood	0.630	0.370
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.630	0.370
R46 Symptoms and signs involving appearance and behaviour	0.629	0.371
R43 Disturbances of smell and taste	0.629	0.371
M87.2 Osteonecrosis due to previous trauma	0.629	0.371
K52.0 Gastro-enteritis and colitis due to radiation	0.629	0.371
H16 Keratitis	0.629	0.371
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.629	0.371
F05 Delirium, not induced by alcohol and other psychoactive substances	0.629	0.371
S64 Injury of nerves at wrist and hand level	0.628	0.371
M86.9 Osteomyelitis, unspecified	0.628	0.372
O20.8 Other haemorrhage in early pregnancy	0.628	0.372
F01 Vascular dementia	0.627	0.373
O03.4 Incomplete, without complication	0.627	0.373
M51.9 Intervertebral disk disorder, unspecified	0.626	0.373
O32.9 Maternal care for malpresentation of foetus, unspecified	0.626	0.373
O32.6 Maternal care for compound presentation	0.626	0.373
O32.4 Maternal care for high head at term	0.626	0.373
O32.3 Maternal care for face, brow and chin presentation	0.626	0.373
O32.2 Maternal care for transverse and oblique lie	0.626	0.373
R20.3 Hyperaesthesia	0.626	0.374
R20.1 Hypoaesthesia of skin	0.626	0.374
R20.0 Anaesthesia of skin	0.626	0.374
Z49.0 Preparatory care for dialysis	0.626	0.374
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.625	0.375
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.625	0.375
S37 Injury of urinary and pelvic organs	0.625	0.375
S36 Injury of intra-abdominal organs	0.625	0.375
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.625	0.375
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.625	0.375
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.625	0.375
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.625	0.375
F70-F79 Mental retardation	0.625	0.375
M85.6 Other cyst of bone	0.624	0.376
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.624	0.376
H91.3 Deaf mutism, not elsewhere classified	0.624	0.376
H91.2 Sudden idiopathic hearing loss	0.624	0.376
H91.1 Presbycusis	0.624	0.376
H91.0 Ototoxic hearing loss	0.624	0.376
T58 Toxic effect of carbon monoxide	0.624	0.376
Q20-Q28 Congenital malformations of the circulatory system	0.623	0.377
Z40.9 Prophylactic surgery, unspecified	0.622	0.378
Y84.0 Cardiac catheterisation	0.621	0.379
J80 Adult respiratory distress syndrome	0.621	0.379
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.620	0.380
H43.8 Other disorders of vitreous body	0.620	0.380
O32.8 Maternal care for other malpresentation of foetus	0.618	0.381
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.618	0.382
Z73 Problems related to life-management difficulty	0.618	0.382
M81.40 Drug-induced osteoporosis (Multiple sites)	0.618	0.382
M91-M94 Chondropathies	0.617	0.382
T93 Sequelae of injuries of lower limb	0.617	0.383
H18.5 Hereditary corneal dystrophies	0.617	0.383
Z45.2 Adjustment and management of vascular access device	0.617	0.383
R71 Abnormality of red blood cells	0.616	0.384
H43.3 Other vitreous opacities	0.616	0.384
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.616	0.384
R79 Other abnormal findings of blood chemistry	0.616	0.384
H92 Otalgia and effusion of ear	0.616	0.384
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.616	0.384
Y60-Y69 Misadventures to patients during surgical and medical care	0.615	0.385
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.615	0.385
H90.5 Sensorineural hearing loss, unspecified	0.615	0.385
S12 Fracture of neck	0.614	0.386
M54.59 Low back pain (Site unspecified)	0.614	0.386
T94 Sequelae of injuries involving multiple and unspecified body regions	0.612	0.388
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.611	0.389
O90 Complications of the puerperium, not elsewhere classified	0.611	0.389
K52.3 Indeterminate colitis	0.610	0.389
R41.2 Retrograde amnesia	0.610	0.390
R41.1 Anterograde amnesia	0.610	0.390
T63 Toxic effect of contact with venomous animals	0.610	0.390
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.609	0.390
S61.7 Multiple open wounds of wrist and hand	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations