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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12925700
log Bayes Factor = 7.5831
Chromosome 16   position 69,793,463  (GRCh37) Explore rs12925700 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H26.9 Cataract, unspecified
0.000 0.003 0.997
E11.9 Without complications
0.000 0.005 0.995
E11 Non-insulin-dependent diabetes mellitus
0.000 0.026 0.974
E11.2 With renal complications
0.000 0.041 0.959
E11.4 With neurological complications
0.000 0.045 0.955
M17.9 Gonarthrosis, unspecified
0.000 0.074 0.926
M17.1 Other primary gonarthrosis
0.000 0.074 0.926
M17 Gonarthrosis [arthrosis of knee]
0.000 0.080 0.920
I42.0 Dilated cardiomyopathy
0.000 0.164 0.836
M10.99 Gout, unspecified (Site unspecified)
0.000 0.196 0.804
M17.4 Other secondary gonarthrosis, bilateral
0.000 0.231 0.769
I42 Cardiomyopathy
0.000 0.238 0.762
I30-I52 Other forms of heart disease
0.000 0.244 0.756
I50 Heart failure
0.000 0.248 0.752
I35 Nonrheumatic aortic valve disorders
0.000 0.251 0.749
E11.6 With other specified complications
0.000 0.262 0.738
I50.9 Heart failure, unspecified
0.000 0.272 0.728
I35.1 Aortic (valve) insufficiency
0.000 0.274 0.726
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.278 0.722
I50.0 Congestive heart failure
0.000 0.281 0.719
I30 Acute pericarditis
0.000 0.289 0.711
E11.7 With multiple complications
0.000 0.301 0.698
I44 Atrioventricular and left bundle-branch block
0.000 0.315 0.685
M17.5 Other secondary gonarthrosis
0.000 0.328 0.671
E11.0 With coma
0.000 0.329 0.670
I30.9 Acute pericarditis, unspecified
0.000 0.332 0.668
I44.7 Left bundle-branch block, unspecified
0.000 0.343 0.657
I36 Nonrheumatic tricuspid valve disorders
0.000 0.349 0.651
E11.3 With ophthalmic complications
0.000 0.358 0.642
M17.2 Posttraumatic gonarthrosis, bilateral
0.000 0.364 0.636
M17.3 Other posttraumatic gonarthrosis
0.000 0.375 0.624
I42.6 Alcoholic cardiomyopathy
0.000 0.377 0.623
I44.2 Atrioventricular block, complete
0.000 0.378 0.622
E11.8 With unspecified complications
0.000 0.399 0.601
I35.8 Other aortic valve disorders
0.000 0.404 0.596
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.425 0.575
I46 Cardiac arrest
0.000 0.431 0.569
I30.1 Infective pericarditis
0.000 0.440 0.560
I42.4 Endocardial fibroelastosis
0.000 0.452 0.548
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.454 0.546
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.454 0.546
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.456 0.544
I52 Other heart disorders in diseases classified elsewhere
0.000 0.458 0.542
I48 Atrial fibrillation and flutter
0.000 0.458 0.542
I41 Myocarditis in diseases classified elsewhere
0.000 0.458 0.542
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.458 0.542
I32 Pericarditis in diseases classified elsewhere
0.000 0.458 0.542
I42.5 Other restrictive cardiomyopathy
0.000 0.468 0.532
I44.4 Left anterior fascicular block
0.000 0.482 0.518
I50.1 Left ventricular failure
0.000 0.485 0.515
I40 Acute myocarditis
0.000 0.488 0.512
I30.8 Other forms of acute pericarditis
0.000 0.490 0.510
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.490 0.510
I51 Complications and ill-defined descriptions of heart disease
0.000 0.490 0.510
I45 Other conduction disorders
0.000 0.493 0.507
I46.0 Cardiac arrest with successful resuscitation
0.000 0.502 0.498
I44.6 Other and unspecified fascicular block
0.000 0.503 0.497
I44.5 Left posterior fascicular block
0.000 0.509 0.491
I42.9 Cardiomyopathy, unspecified
0.000 0.526 0.474
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.533 0.466
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.533 0.466
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.533 0.466
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.533 0.466
I45.9 Conduction disorder, unspecified
0.000 0.542 0.458
I33 Acute and subacute endocarditis
0.000 0.545 0.454
E11.1 With ketoacidosis
0.000 0.553 0.447
I37 Pulmonary valve disorders
0.000 0.555 0.445
I35.9 Aortic valve disorder, unspecified
0.000 0.555 0.445
I42.8 Other cardiomyopathies
0.000 0.561 0.439
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.574 0.426
I51.6 Cardiovascular disease, unspecified
0.000 0.575 0.425
I46.1 Sudden cardiac death, so described
0.000 0.592 0.408
I51.0 Cardiac septal defect, acquired
0.000 0.605 0.395
E11.5 With peripheral circulatory complications
0.000 0.606 0.394
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.607 0.393
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.609 0.390
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.609 0.390
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.609 0.390
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.611 0.388
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.611 0.388
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.611 0.388
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.611 0.388
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.611 0.388
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.611 0.388
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.611 0.388
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.611 0.388
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.611 0.388
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.611 0.388
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.611 0.388
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.611 0.388
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.611 0.388
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.611 0.388
I48.4 Atypical atrial flutter
0.000 0.611 0.388
I48.3 Typical atrial flutter
0.000 0.611 0.388
I48.2 Chronic atrial fibrillation
0.000 0.611 0.388
I48.1 Persistent atrial fibrillation
0.000 0.611 0.388
I48.0 Paroxysmal atrial fibrillation
0.000 0.611 0.388
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.611 0.388
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.611 0.388
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.611 0.388
I40.9 Acute myocarditis, unspecified
0.000 0.612 0.388
I45.8 Other specified conduction disorders
0.000 0.618 0.382
I44.3 Other and unspecified atrioventricular block
0.000 0.621 0.379
I33.9 Acute endocarditis, unspecified
0.000 0.622 0.378
I45.4 Nonspecific intraventricular block
0.000 0.627 0.373
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.630 0.370
I40.8 Other acute myocarditis
0.000 0.633 0.367
I40.1 Isolated myocarditis
0.000 0.633 0.367
I51.5 Myocardial degeneration
0.000 0.634 0.365
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.634 0.365
I45.6 Preexcitation syndrome
0.000 0.637 0.363
I10-I15 Hypertensive diseases
0.000 0.641 0.359
Chapter IX Diseases of the circulatory system
0.000 0.642 0.358
I10 Essential (primary) hypertension
0.000 0.648 0.352
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.649 0.351
I45.5 Other specified heart block
0.000 0.650 0.350
E10-E14 Diabetes mellitus
0.000 0.657 0.343
I45.2 Bifascicular block
0.000 0.660 0.340
I51.4 Myocarditis, unspecified
0.000 0.663 0.337
I15 Secondary hypertension
0.000 0.664 0.336
I95 Hypotension
0.000 0.665 0.335
I51.7 Cardiomegaly
0.000 0.665 0.335
I44.1 Atrioventricular block, second degree
0.000 0.666 0.334
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.666 0.334
I35.0 Aortic (valve) stenosis
0.000 0.667 0.333
I95.1 Orthostatic hypotension
0.000 0.675 0.325
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.677 0.323
I37.9 Pulmonary valve disorder, unspecified
0.000 0.680 0.319
I37.8 Other pulmonary valve disorders
0.000 0.680 0.319
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.680 0.319
I45.0 Right fascicular block
0.000 0.681 0.319
I95.2 Hypotension due to drugs
0.000 0.687 0.313
I40.0 Infective myocarditis
0.000 0.691 0.308
I31 Other diseases of pericardium
0.000 0.695 0.305
I15.1 Hypertension secondary to other renal disorders
0.000 0.698 0.302
I11 Hypertensive heart disease
0.000 0.699 0.301
I45.1 Other and unspecified right bundle-branch block
0.000 0.708 0.292
E14 Unspecified diabetes mellitus
0.000 0.709 0.291
I37.0 Pulmonary valve stenosis
0.000 0.712 0.287
I15.9 Seconday hypertension, unspecified
0.000 0.714 0.286
E14.9 Without complications
0.000 0.716 0.284
I34 Nonrheumatic mitral valve disorders
0.000 0.719 0.281
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.725 0.275
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.725 0.274
I42.2 Other hypertrophic cardiomyopathy
0.000 0.730 0.270
I37.1 Pulmonary valve insufficiency
0.000 0.732 0.268
I46.9 Cardiac arrest, unspecified
0.000 0.732 0.268
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.737 0.263
I13 Hypertensive heart and renal disease
0.000 0.742 0.257
I00-I02 Acute rheumatic fever
0.000 0.746 0.254
I51.8 Other ill-defined heart diseases
0.000 0.746 0.254
I45.3 Trifascicular block
0.000 0.750 0.249
I05-I09 Chronic rheumatic heart diseases
0.000 0.751 0.249
I51.9 Heart disease, unspecified
0.000 0.754 0.246
E12 Malnutrition-related diabetes mellitus
0.000 0.754 0.246
I15.0 Renovascular hypertension
0.000 0.755 0.245
I15.8 Other secondary hypertension
0.000 0.759 0.241
I15.2 Hypertension secondary to endocrine disorders
0.000 0.759 0.241
I31.1 Chronic constrictive pericarditis
0.000 0.760 0.240
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.760 0.240
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.760 0.240
I98.0 Cardiovascular syphilis
0.000 0.760 0.240
I05 Rheumatic mitral valve diseases
0.000 0.760 0.240
I97.1 Other functional disturbances following cardiac surgery
0.000 0.763 0.237
I95.0 Idiopathic hypotension
0.000 0.764 0.236
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.769 0.231
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.769 0.230
E14.2 Withrenal complications
0.000 0.770 0.230
I44.0 Atrioventricular block, first degree
0.000 0.770 0.230
I31.8 Other specified diseases of pericardium
0.000 0.781 0.219
I31.2 Haemopericardium, not elsewhere classified
0.000 0.781 0.219
I05.9 Mitral valve disease, unspecified
0.000 0.781 0.219
E13 Other specified diabetes mellitus
0.000 0.784 0.216
I05.1 Rheumatic mitral insufficiency
0.000 0.784 0.216
I31.0 Chronic adhesive pericarditis
0.000 0.790 0.210
E14.7 With multiple complications
0.000 0.791 0.209
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.792 0.208
E14.1 With ketoacidosis
0.000 0.793 0.207
I95.8 Other hypotension
0.000 0.796 0.204
E14.5 With peripheral circulatory complications
0.000 0.796 0.203
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.798 0.202
I97.0 Postcardiotomy syndrome
0.000 0.800 0.200
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.802 0.197
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.803 0.197
E14.0 With coma
0.000 0.804 0.195
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.807 0.193
E14.6 With other specified complications
0.000 0.809 0.191
I05.2 Mitral stenosis with insufficiency
0.000 0.812 0.188
I34.0 Mitral (valve) insufficiency
0.000 0.814 0.186
E14.8 With unspecified complications
0.000 0.814 0.186
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.815 0.185
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.815 0.185
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.815 0.185
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.815 0.185
I02 Rheumatic chorea
0.000 0.818 0.182
I01 Rheumatic fever with heart involvement
0.000 0.818 0.182
I00 Rheumatic fever without mention of heart involvement
0.000 0.821 0.179
E12.9 Without complications
0.000 0.823 0.176
E12.8 With unspecified complications
0.000 0.823 0.176
E12.7 With multiple complications
0.000 0.823 0.176
E12.6 With other specified complications
0.000 0.823 0.176
E12.5 With peripheral circulatory complications
0.000 0.823 0.176
E12.4 With neurological complications
0.000 0.823 0.176
E12.3 With ophthalmic complications
0.000 0.823 0.176
E12.2 With renal complications
0.000 0.823 0.176
E12.1 With ketoacidosis
0.000 0.823 0.176
E12.0 With coma
0.000 0.823 0.176
I12 Hypertensive renal disease
0.000 0.826 0.174
I05.8 Other mitral valve diseases
0.000 0.828 0.172
I06 Rheumatic aortic valve diseases
0.000 0.839 0.161
E14.4 With neurological complications
0.000 0.841 0.159
I31.9 Disease of pericardium, unspecified
0.000 0.843 0.157
E13.8 With unspecified complications
0.000 0.845 0.155
E13.7 With multiple complications
0.000 0.845 0.155
E13.6 With other specified complications
0.000 0.845 0.155
E13.5 With peripheral circulatory complications
0.000 0.845 0.155
E13.4 With neurological complications
0.000 0.845 0.155
E13.2 With renal complications
0.000 0.845 0.155
E13.1 With ketoacidosis
0.000 0.845 0.155
E13.0 With coma
0.000 0.845 0.155
I05.0 Mitral stenosis
0.000 0.847 0.153
E14.3 With ophthalmic complications
0.000 0.854 0.146
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.855 0.145
I09 Other rheumatic heart diseases
0.000 0.855 0.145
E65-E68 Obesity and other hyperalimentation
0.000 0.855 0.145
E13.9 Without complications
0.000 0.857 0.143
E13.3 With ophthalmic complications
0.000 0.860 0.140
M17.0 Primary gonarthrosis, bilateral
0.000 0.860 0.139
E40-E46 Malnutrition
0.000 0.861 0.139
E65 Localised adiposity
0.000 0.862 0.138
E46 Unspecified protein-energy malnutrition
0.000 0.865 0.135
E66 Obesity
0.000 0.867 0.133
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.869 0.131
I01.8 Other acute rheumatic heart disease
0.000 0.869 0.131
I01.2 Acute rheumatic myocarditis
0.000 0.869 0.131
I01.1 Acute rheumatic endocarditis
0.000 0.869 0.131
I01.0 Acute rheumatic pericarditis
0.000 0.869 0.131
I02.9 Rheumatic chorea without heart involvement
0.000 0.869 0.131
I02.0 Rheumatic chorea with heart involvement
0.000 0.869 0.131
I07 Rheumatic tricuspid valve diseases
0.000 0.872 0.127
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.878 0.122
E66.9 Obesity, unspecified
0.000 0.880 0.120
I06.1 Rheumatic aortic insufficiency
0.000 0.882 0.117
I12.0 Hypertensive renal disease with renal failure
0.000 0.883 0.117
I06.8 Other rheumatic aortic valve diseases
0.000 0.884 0.115
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.884 0.115
I38 Endocarditis, valve unspecified
0.000 0.886 0.114
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.887 0.113
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.893 0.107
I47 Paroxysmal tachycardia
0.000 0.893 0.107
I06.0 Rheumatic aortic stenosis
0.000 0.895 0.104
I09.8 Other specified rheumatic heart diseases
0.000 0.896 0.104
I09.2 Chronic rheumatic pericarditis
0.000 0.896 0.104
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.896 0.104
I09.0 Rheumatic myocarditis
0.000 0.896 0.104
E67 Other hyperalimentation
0.000 0.896 0.104
E68 Sequelae of hyperalimentation
0.000 0.896 0.104
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.900 0.100
E45 Retarded development following protein-energy malnutrition
0.000 0.900 0.100
E43 Unspecified severe protein-energy malnutrition
0.000 0.900 0.100
E42 Marasmic kwashiorkor
0.000 0.900 0.100
E41 Nutritional marasmus
0.000 0.900 0.100
E40 Kwashiorkor
0.000 0.900 0.100
E66.0 Obesity due to excess calories
0.000 0.901 0.099
M10.9 Gout, unspecified
0.000 0.902 0.098
I99 Other and unspecified disorders of circulatory system
0.001 0.902 0.097
E66.1 Drug-induced obesity
0.000 0.904 0.096
I33.0 Acute and subacute infective endocarditis
0.001 0.906 0.093
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.908 0.092
I07.9 Tricuspid valve disease, unspecified
0.000 0.908 0.091
I07.8 Other tricuspid valve diseases
0.000 0.908 0.091
I07.2 Tricuspid stenosis with insufficiency
0.000 0.908 0.091
I07.0 Tricuspid stenosis
0.000 0.908 0.091
I08 Multiple valve diseases
0.000 0.918 0.082
I31.3 Pericardial effusion (noninflammatory)
0.000 0.919 0.081
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.922 0.077
I28 Other diseases of pulmonary vessels
0.000 0.923 0.077
E67.8 Other specified hyperalimentation
0.000 0.925 0.075
E67.3 Hypervitaminosis D
0.000 0.925 0.075
E67.2 Megavitamin-B6 syndrome
0.000 0.925 0.075
E67.1 Hypercarotenaemia
0.000 0.925 0.075
E67.0 Hypervitaminosis A
0.000 0.925 0.075
I47.0 Reentry ventricular arrhythmia
0.000 0.928 0.072
E44.1 Mild protein-energy malnutrition
0.000 0.928 0.072
E44.0 Moderate protein-energy malnutrition
0.000 0.928 0.072
I09.9 Rheumatic heart disease, unspecified
0.001 0.929 0.070
M10.98 Gout, unspecified (Other)
0.000 0.930 0.070
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.930 0.070
M10.91 Gout, unspecified (Shoulder region)
0.000 0.930 0.070
M10.93 Gout, unspecified (Forearm)
0.000 0.931 0.069
E15 Nondiabetic hypoglycaemic coma
0.000 0.934 0.066
M20.1 Hallux valgus (acquired)
0.065 0.935 0.000
M10.94 Gout, unspecified (Hand)
0.000 0.935 0.065
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.937 0.063
K80 Cholelithiasis
0.000 0.938 0.062
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.940 0.060
I08.9 Multiple valve disease, unspecified
0.000 0.940 0.059
I12.9 Hypertensive renal disease without renal failure
0.000 0.941 0.059
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.941 0.058
K80.4 Calculus of bile duct with cholecystitis
0.000 0.942 0.058
M10.90 Gout, unspecified (Multiple sites)
0.000 0.942 0.058
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.942 0.058
I26 Pulmonary embolism
0.000 0.942 0.058
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.944 0.056
I49 Other cardiac arrhythmias
0.000 0.944 0.056
H26 Other cataract
0.000 0.944 0.056
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.944 0.055
I28.1 Aneurysm of pulmonary artery
0.000 0.944 0.055
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.944 0.055
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.945 0.055
M10.92 Gout, unspecified (Upper arm)
0.000 0.945 0.054
E16 Other disorders of pancreatic internal secretion
0.000 0.946 0.054
I08.8 Other multiple valve diseases
0.000 0.948 0.052
E00-E07 Disorders of thyroid gland
0.000 0.949 0.051
I28.8 Other specified diseases of pulmonary vessels
0.000 0.949 0.051
E66.8 Other obesity
0.000 0.949 0.051
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.950 0.050
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.950 0.050
M10.96 Gout, unspecified (Lower leg)
0.000 0.951 0.048
I49.4 Other and unspecified premature depolarisation
0.000 0.952 0.048
K80.3 Calculus of bile duct with cholangitis
0.000 0.955 0.045
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.956 0.044
I49.9 Cardiac arrhythmia, unspecified
0.000 0.957 0.043
M20 Acquired deformities of fingers and toes
0.043 0.957 0.000
E07 Other disorders of thyroid
0.000 0.957 0.043
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.957 0.043
C71.9 Brain, unspecified
0.043 0.957 0.000
M20.5 Other deformities of toe(s) (acquired)
0.042 0.958 0.000
C71 Malignant neoplasm of brain
0.042 0.958 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.958 0.042
K80.8 Other cholelithiasis
0.000 0.959 0.041
H26.0 Infantile, juvenile and presenile cataract
0.000 0.959 0.041
I47.2 Ventricular tachycardia
0.000 0.959 0.041
I07.1 Tricuspid insufficiency
0.000 0.960 0.040
I49.2 Junctional premature depolarisation
0.000 0.960 0.040
M20.3 Other deformity of hallux (acquired)
0.040 0.960 0.000
I20-I25 Ischaemic heart diseases
0.000 0.960 0.040
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.961 0.039
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.961 0.039
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.961 0.039
E16.4 Abnormal secretion of gastrin
0.000 0.961 0.039
E16.3 Increased secretion of glucagon
0.000 0.961 0.039
C71.2 Temporal lobe
0.039 0.961 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.038 0.962 0.000
E16.1 Other hypoglycaemia
0.000 0.962 0.038
E20-E35 Disorders of other endocrine glands
0.000 0.962 0.038
H26.3 Drug-induced cataract
0.000 0.962 0.037
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.963 0.037
E00 Congenital iodine-deficiency syndrome
0.000 0.963 0.037
E27 Other disorders of adrenal gland
0.000 0.963 0.037
E07.8 Other specified disorders of thyroid
0.000 0.964 0.036
E50-E64 Other nutritional deficiencies
0.000 0.964 0.036
E05.9 Thyrotoxicosis, unspecified
0.000 0.964 0.036
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.965 0.035
C71.1 Frontal lobe
0.035 0.965 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.966 0.034
C71.6 Cerebellum
0.034 0.966 0.000
C71.0 Cerebrum, except lobes and ventricles
0.034 0.966 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.966 0.034
C71.5 Cerebral ventricle
0.033 0.967 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.967 0.033
I24 Other acute ischaemic heart diseases
0.000 0.967 0.033
E03 Other hypothyroidism
0.000 0.967 0.033
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.967 0.032
E27.2 Addisonian crisis
0.000 0.968 0.032
E27.1 Primary adrenocortical insufficiency
0.000 0.968 0.032
C71.8 Overlapping lesion of brain
0.032 0.968 0.000
I34.1 Mitral (valve) prolapse
0.000 0.969 0.031
E07.1 Dyshormogenetic goitre
0.000 0.969 0.031
E07.0 Hypersecretion of calcitonin
0.000 0.969 0.031
C71.4 Occipital lobe
0.031 0.969 0.000
E05.8 Other thyrotoxicosis
0.000 0.969 0.031
H26.1 Traumatic cataract
0.000 0.969 0.031
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.970 0.030
C71.3 Parietal lobe
0.030 0.970 0.000
T78.3 Angioneurotic oedema
0.030 0.970 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.970 0.029
C71.7 Brain stem
0.029 0.971 0.000
I95.9 Hypotension, unspecified
0.000 0.971 0.029
E06 Thyroiditis
0.000 0.971 0.029
E05.5 Thyroid crisis or storm
0.000 0.971 0.028
E05.4 Thyrotoxicosis factitia
0.000 0.971 0.028
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.971 0.028
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.971 0.028
I49.1 Atrial premature depolarisation
0.000 0.972 0.028
M10 Gout
0.000 0.972 0.028
H26.2 Complicated cataract
0.000 0.973 0.027
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.973 0.027
E32 Diseases of thymus
0.000 0.973 0.027
E30 Disorders of puberty, not elsewhere classified
0.000 0.973 0.027
E31 Polyglandular dysfunction
0.000 0.973 0.027
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.973 0.027
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.973 0.027
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.973 0.027
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.973 0.027
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.973 0.027
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.973 0.027
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.973 0.027
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.973 0.027
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.973 0.027
E29 Testicular dysfunction
0.000 0.973 0.027
E27.5 Adrenomedullary hyperfunction
0.000 0.973 0.027
E27.0 Other adrenocortical overactivity
0.000 0.973 0.027
E23.7 Disorder of pituitary gland, unspecified
0.000 0.973 0.027
H26.8 Other specified cataract
0.000 0.973 0.027
E24 Cushing's syndrome
0.000 0.973 0.027
I23 Certain current complications following acute myocardial infarction
0.000 0.973 0.026
E26 Hyperaldosteronism
0.000 0.974 0.026
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.974 0.026
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.974 0.026
E63 Other nutritional deficiencies
0.000 0.974 0.026
E50 Vitamin A deficiency
0.000 0.974 0.026
E60 Dietary zinc deficiency
0.000 0.974 0.026
E59 Dietary selenium deficiency
0.000 0.974 0.026
E54 Ascorbic acid deficiency
0.000 0.974 0.026
E52 Niacin deficiency [pellagra]
0.000 0.974 0.026
E25 Adrenogenital disorders
0.000 0.974 0.026
E03.9 Hypothyroidism, unspecified
0.000 0.974 0.026
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.975 0.025
I27 Other pulmonary heart diseases
0.000 0.975 0.025
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.025 0.975 0.000
E56 Other vitamin deficiencies
0.000 0.976 0.024
T78 Adverse effects, not elsewhere classified
0.024 0.976 0.000
E03.5 Myxoedema coma
0.000 0.976 0.023
E03.4 Atrophy of thyroid (acquired)
0.000 0.976 0.023
E03.3 Postinfectious hypothyroidism
0.000 0.976 0.023
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.976 0.024
E23.2 Diabetes insipidus
0.000 0.977 0.023
T78.1 Other adverse food reactions, not elsewhere classified
0.023 0.977 0.000
E51 Thiamine deficiency
0.000 0.977 0.023
E03.1 Congenital hypothyroidism without goitre
0.000 0.977 0.023
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.977 0.023
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.977 0.023
E06.5 Other chronic thyroiditis
0.000 0.977 0.023
E58 Dietary calcium deficiency
0.000 0.977 0.022
I24.1 Dressler's syndrome
0.000 0.977 0.022
E27.9 Disorder of adrenal gland, unspecified
0.000 0.978 0.022
E10 Insulin-dependent diabetes mellitus
0.000 0.978 0.022
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.979 0.021
E23.1 Drug-induced hypopituitarism
0.000 0.979 0.021
E06.9 Thyroiditis, unspecified
0.000 0.979 0.021
E55 Vitamin D deficiency
0.000 0.979 0.021
I49.5 Sick sinus syndrome
0.000 0.979 0.021
E06.4 Drug-induced thyroiditis
0.000 0.979 0.021
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.979 0.021
E06.0 Acute thyroiditis
0.000 0.979 0.021
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.021 0.979 0.000
I49.3 Ventricular premature depolarisation
0.000 0.979 0.021
E61 Deficiency of other nutrient elements
0.000 0.979 0.020
E03.8 Other specified hypothyroidism
0.000 0.980 0.020
E26.9 Hyperaldosteronism, unspecified
0.000 0.980 0.020
E16.2 Hypoglycaemia, unspecified
0.000 0.980 0.020
C69 Malignant neoplasm of eye and adnexa
0.020 0.980 0.000
M10.4 Other secondary gout
0.000 0.980 0.020
M10.3 Gout due to impairment of renal function
0.000 0.980 0.020
M10.2 Drug-induced gout
0.000 0.980 0.020
M10.1 Lead-induced gout
0.000 0.980 0.020
M48.02 Spinal stenosis (Cervical region)
0.000 0.980 0.020
H26.4 After-cataract
0.000 0.980 0.020
E29.1 Testicular hypofunction
0.000 0.980 0.020
E30.9 Disorder of puberty, unspecified
0.000 0.980 0.020
E30.8 Other disorders of puberty
0.000 0.980 0.020
E30.1 Precocious puberty
0.000 0.980 0.020
E30.0 Delayed puberty
0.000 0.980 0.020
E32.9 Disease of thymus, unspecified
0.000 0.980 0.020
E32.8 Other diseases of thymus
0.000 0.980 0.020
E32.1 Abscess of thymus
0.000 0.980 0.020
E32.0 Persistent hyperplasia of thymus
0.000 0.980 0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.980 0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.980 0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.980 0.020
E31.9 Polyglandular dysfunction, unspecified
0.000 0.980 0.020
E31.8 Other polyglandular dysfunction
0.000 0.980 0.020
E31.1 Polyglandular hyperfunction
0.000 0.980 0.020
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.980 0.020
T78.2 Anaphylactic shock, unspecified
0.020 0.980 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.980 0.020
E24.0 Pituitary-dependent Cushing's disease
0.000 0.980 0.020
E24.9 Cushing's syndrome, unspecified
0.000 0.980 0.019
E29.8 Other testicular dysfunction
0.000 0.980 0.019
E29.0 Testicular hyperfunction
0.000 0.980 0.019
M20.4 Other hammer toe(s) (acquired)
0.019 0.981 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.981 0.019
E24.3 Ectopic ACTH syndrome
0.000 0.981 0.019
E24.1 Nelson's syndrome
0.000 0.981 0.019
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.981 0.019
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.981 0.019
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.981 0.019
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.981 0.019
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.981 0.019
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.981 0.019
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.981 0.019
E26.8 Other hyperaldosteronism
0.000 0.981 0.019
E26.1 Secondary hyperaldosteronism
0.000 0.981 0.019
E23.0 Hypopituitarism
0.000 0.981 0.019
E06.1 Subacute thyroiditis
0.000 0.981 0.019
C69.3 Choroid
0.019 0.981 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.981 0.019
E50.8 Other manifestations of vitamin A deficiency
0.000 0.981 0.019
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.981 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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