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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142507408
log Bayes Factor = 2.75227
Chromosome 8   position 106,455,558  (GRCh37) Explore rs142507408 on Ensembl!
Variant rs142507408 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
Chapter XIV Diseases of the genitourinary system
0.966 0.034 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.962 0.038 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.956 0.044 0.000
Chapter X Diseases of the respiratory system
0.936 0.064 0.000
R50-R69 General symptoms and signs
0.897 0.103 0.000
Z96 Presence of other functional implants
0.897 0.103 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.886 0.114 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.882 0.118 0.000
J40-J47 Chronic lower respiratory diseases
0.868 0.131 0.000
Chapter II Neoplasms
0.862 0.138 0.000
Chapter I Certain infectious and parasitic diseases
0.851 0.149 0.000
Chapter IX Diseases of the circulatory system
0.849 0.151 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.843 0.157 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.842 0.158 0.000
N17-N19 Renal failure
0.835 0.165 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.832 0.168 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.831 0.169 0.000
R69 Unknown and unspecified causes of morbidity
0.831 0.169 0.000
Z87 Personal history of other diseases and conditions
0.824 0.176 0.000
N40-N51 Diseases of male genital organs
0.817 0.183 0.000
N20-N23 Urolithiasis
0.809 0.191 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.808 0.192 0.000
Z92 Personal history of medical treatment
0.806 0.194 0.000
N30-N39 Other diseases of urinary system
0.798 0.202 0.000
Chapter VII Diseases of the eye and adnexa
0.795 0.205 0.000
Chapter V Mental and behavioural disorders
0.791 0.209 0.000
J44 Other chronic obstructive pulmonary disease
0.790 0.210 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.787 0.213 0.000
R63 Symptoms and signs concerning food and fluid intake
0.779 0.221 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.778 0.222 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.776 0.224 0.000
Z96.0 Presence of urogenital implants
0.768 0.232 0.000
Z96.1 Presence of intraocular lens
0.755 0.245 0.000
Z96.8 Presence of other specified functional implants
0.754 0.246 0.000
R47-R49 Symptoms and signs involving speech and voice
0.753 0.247 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.752 0.248 0.000
S80-S89 Injuries to the knee and lower leg
0.749 0.251 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.742 0.258 0.000
I60-I69 Cerebrovascular diseases
0.741 0.259 0.000
J09-J18 Influenza and pneumonia
0.740 0.260 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.738 0.262 0.000
J43 Emphysema
0.738 0.262 0.000
Chapter XI Diseases of the digestive system
0.737 0.263 0.000
N00-N08 Glomerular diseases
0.732 0.268 0.000
A00-A09 Intestinal infectious diseases
0.729 0.271 0.000
J00-J06 Acute upper respiratory infections
0.728 0.272 0.000
N17 Acute renal failure
0.725 0.275 0.000
Z87.1 Personal history of diseases of the digestive system
0.720 0.280 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.719 0.281 0.000
J20-J22 Other acute lower respiratory infections
0.718 0.282 0.000
Z88.0 Personal history of allergy to penicillin
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.715 0.285 0.000
Chapter VIII Diseases of the ear and mastoid process
0.713 0.287 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.711 0.288 0.000
Chapter VI Diseases of the nervous system
0.710 0.290 0.000
N10-N16 Renal tubulo-interstitial diseases
0.709 0.291 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.709 0.291 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.708 0.292 0.000
N25-N29 Other disorders of kidney and ureter
0.707 0.293 0.000
R56 Convulsions, not elsewhere classified
0.706 0.294 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.705 0.295 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.700 0.300 0.000
J47 Bronchiectasis
0.700 0.300 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.699 0.301 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.695 0.305 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.695 0.305 0.000
Z86 Personal history of certain other diseases
0.693 0.307 0.000
N99-N99 Other disorders of the genitourinary system
0.692 0.307 0.000
N20 Calculus of kidney and ureter
0.691 0.309 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.690 0.310 0.000
Z97 Presence of other devices
0.690 0.310 0.000
Z94 Transplanted organ and tissue status
0.690 0.310 0.000
Z93 Artificial opening status
0.690 0.310 0.000
Z89 Acquired absence of limb
0.690 0.310 0.000
Z84 Family history of other conditions
0.690 0.310 0.000
Z83 Family history of other specific disorders
0.690 0.310 0.000
Z81 Family history of mental and behavioural disorders
0.690 0.310 0.000
M20-M25 Other joint disorders
0.690 0.310 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.687 0.313 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.685 0.314 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.685 0.314 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.685 0.315 0.000
J90-J94 Other diseases of pleura
0.683 0.317 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.680 0.320 0.000
Z13 Special screening examination for other diseases and disorders
0.680 0.320 0.000
Z95.4 Presence of other heart-valve replacement
0.679 0.321 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.678 0.322 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.677 0.323 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.677 0.323 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.676 0.324 0.000
N60-N64 Disorders of breast
0.674 0.326 0.000
S00-S09 Injuries to the head
0.674 0.326 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.673 0.326 0.000
Z80 Family history of malignant neoplasm
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.671 0.329 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.671 0.329 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.671 0.329 0.000
J60-J70 Lung diseases due to external agents
0.671 0.329 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.671 0.329 0.000
Chapter XX External causes of morbidity and mortality
0.670 0.330 0.000
M05-M14 Inflammatory polyarthropathies
0.667 0.333 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.666 0.334 0.000
R50 Fever of unknown origin
0.666 0.334 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.664 0.336 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.663 0.336 0.000
A30-A49 Other bacterial diseases
0.663 0.337 0.000
Z98 Other postsurgical states
0.662 0.338 0.000
Z95.1 Presence of aortocoronary bypass graft
0.658 0.341 0.000
E70-E90 Metabolic disorders
0.658 0.342 0.000
S60-S69 Injuries to the wrist and hand
0.653 0.346 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.653 0.347 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.652 0.348 0.000
S70-S79 Injuries to the hip and thigh
0.651 0.349 0.000
R63.4 Abnormal weight loss
0.651 0.349 0.000
Z12 Special screening examination for neoplasms
0.650 0.350 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.650 0.350 0.000
I20-I25 Ischaemic heart diseases
0.650 0.350 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.650 0.350 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.649 0.351 0.000
Z88.6 Personal history of allergy to analgesic agent
0.646 0.354 0.000
N17.9 Acute renal failure, unspecified
0.646 0.354 0.000
I84 Haemorrhoids
0.645 0.355 0.000
O80-O84 Delivery
0.645 0.355 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.644 0.356 0.000
J43.9 Emphysema, unspecified
0.644 0.356 0.000
N30 Cystitis
0.644 0.356 0.000
R68 Other general symptoms and signs
0.643 0.357 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.643 0.357 0.000
R62 Lack of expected normal physiological development
0.643 0.357 0.000
R61 Hyperhidrosis
0.643 0.357 0.000
R60 Oedema, not elsewhere classified
0.643 0.357 0.000
R59 Enlarged lymph nodes
0.643 0.357 0.000
R57 Shock, not elsewhere classified
0.643 0.357 0.000
R52 Pain, not elsewhere classified
0.643 0.357 0.000
R64 Cachexia
0.643 0.357 0.000
R58 Haemorrhage, not elsewhere classified
0.643 0.357 0.000
R54 Senility
0.643 0.357 0.000
Z96.9 Presence of functional implant, unspecified
0.643 0.357 0.000
Z96.7 Presence of other bone and tendon implants
0.643 0.357 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.643 0.357 0.000
Z96.4 Presence of endocrine implants
0.643 0.357 0.000
Z96.3 Presence of artificial larynx
0.643 0.357 0.000
Z96.2 Presence of otological and audiological implants
0.643 0.357 0.000
K55-K64 Other diseases of intestines
0.641 0.359 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.641 0.359 0.000
D10-D36 Benign neoplasms
0.640 0.360 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.640 0.360 0.000
Z03.8 Observation for other suspected diseases and conditions
0.639 0.361 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.635 0.365 0.000
Z10 Routine general health check-up of defined subpopulation
0.635 0.365 0.000
Z04 Examination and observation for other reasons
0.635 0.365 0.000
Z02 Examination and encounter for administrative purposes
0.635 0.365 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.635 0.365 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.635 0.365 0.000
R30-R39 Symptoms and signs involving the urinary system
0.635 0.365 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.635 0.365 0.000
M50-M54 Other dorsopathies
0.635 0.365 0.000
R63.0 Anorexia
0.634 0.366 0.000
Z45 Adjustment and management of implanted device
0.634 0.366 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.634 0.366 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.632 0.368 0.000
T79-T79 Certain early complications of trauma
0.632 0.368 0.000
T66-T78 Other and unspecified effects of external causes
0.632 0.368 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.632 0.368 0.000
T33-T35 Frostbite
0.632 0.368 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.632 0.368 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.632 0.368 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.632 0.368 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.632 0.368 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.632 0.368 0.000
T00-T07 Injuries involving multiple body regions
0.632 0.368 0.000
S90-S99 Injuries to the ankle and foot
0.632 0.368 0.000
S40-S49 Injuries to the shoulder and upper arm
0.632 0.368 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.632 0.368 0.000
S20-S29 Injuries to the thorax
0.632 0.368 0.000
S10-S19 Injuries to the neck
0.632 0.368 0.000
M45-M49 Spondylopathies
0.632 0.368 0.000
R53 Malaise and fatigue
0.631 0.368 0.000
Z95.0 Presence of cardiac pacemaker
0.629 0.371 0.000
Z72 Problems related to lifestyle
0.628 0.372 0.000
E00-E07 Disorders of thyroid gland
0.625 0.375 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.625 0.375 0.000
N39 Other disorders of urinary system
0.623 0.377 0.000
J41 Simple and mucopurulent chronic bronchitis
0.623 0.377 0.000
J46 Status asthmaticus
0.623 0.377 0.000
J42 Unspecified chronic bronchitis
0.623 0.377 0.000
J40 Bronchitis, not specified as acute or chronic
0.623 0.377 0.000
N18 Chronic renal failure
0.622 0.378 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.622 0.378 0.000
O60-O75 Complications of labour and delivery
0.622 0.378 0.000
Z47 Other orthopaedic follow-up care
0.621 0.379 0.000
H30-H36 Disorders of choroid and retina
0.621 0.379 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.621 0.379 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.620 0.380 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.619 0.381 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.618 0.382 0.000
D00-D09 In situ neoplasms
0.618 0.382 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.618 0.382 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.618 0.382 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.618 0.382 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.618 0.382 0.000
C64-C68 Malignant neoplasms of urinary tract
0.618 0.382 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.618 0.382 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.618 0.382 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.618 0.382 0.000
C15-C26 Malignant neoplasms of digestive organs
0.618 0.382 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.618 0.382 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.618 0.382 0.000
S50-S59 Injuries to the elbow and forearm
0.616 0.384 0.000
R94 Abnormal results of function studies
0.616 0.384 0.000
I67 Other cerebrovascular diseases
0.615 0.385 0.000
R51 Headache
0.611 0.389 0.000
B99-B99 Other infectious diseases
0.610 0.389 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.610 0.389 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.610 0.389 0.000
B65-B83 Helminthiases
0.610 0.389 0.000
B50-B64 Protozoal diseases
0.610 0.389 0.000
B35-B49 Mycoses
0.610 0.389 0.000
B25-B34 Other viral diseases
0.610 0.389 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.610 0.389 0.000
B15-B19 Viral hepatitis
0.610 0.389 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.610 0.389 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.610 0.389 0.000
A80-A89 Viral infections of the central nervous system
0.610 0.389 0.000
A75-A79 Rickettsioses
0.610 0.389 0.000
A70-A74 Other diseases caused by chlamydiae
0.610 0.389 0.000
A65-A69 Other spirochaetal diseases
0.610 0.389 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.610 0.389 0.000
A20-A28 Certain zoonotic bacterial diseases
0.610 0.389 0.000
A15-A19 Tuberculosis
0.610 0.389 0.000
N19 Unspecified renal failure
0.610 0.390 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.610 0.390 0.000
I05-I09 Chronic rheumatic heart diseases
0.608 0.391 0.000
I00-I02 Acute rheumatic fever
0.608 0.391 0.000
R49 Voice disturbances
0.608 0.392 0.000
S80 Superficial injury of lower leg
0.608 0.392 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.607 0.392 0.000
N20.0 Calculus of kidney
0.606 0.394 0.000
S82 Fracture of lower leg, including ankle
0.605 0.395 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.604 0.396 0.000
O85-O92 Complications predominantly related to the puerperium
0.604 0.396 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.604 0.396 0.000
O00-O08 Pregnancy with abortive outcome
0.604 0.396 0.000
N32 Other disorders of bladder
0.604 0.396 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.603 0.396 0.000
Z95.3 Presence of xenogenic heart valve
0.603 0.396 0.000
Z95.2 Presence of prosthetic heart valve
0.603 0.396 0.000
Z96.6 Presence of orthopaedic joint implants
0.603 0.397 0.000
Z87.0 Personal history of diseases of the respiratory system
0.601 0.399 0.000
J18 Pneumonia, organism unspecified
0.600 0.400 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.599 0.401 0.000
Z46 Fitting and adjustment of other devices
0.598 0.402 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.596 0.404 0.000
M91-M94 Chondropathies
0.596 0.404 0.000
M86-M90 Other osteopathies
0.596 0.404 0.000
M65-M68 Disorders of synovium and tendon
0.596 0.404 0.000
M60-M63 Disorders of muscles
0.596 0.404 0.000
M40-M43 Deforming dorsopathies
0.596 0.404 0.000
M00-M03 Infectious arthropathies
0.596 0.404 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.596 0.404 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.596 0.404 0.000
Z88.5 Personal history of allergy to narcotic agent
0.596 0.404 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.596 0.404 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.596 0.404 0.000
Z88.2 Personal history of allergy to sulphonamides
0.596 0.404 0.000
I30-I52 Other forms of heart disease
0.595 0.405 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.594 0.406 0.000
Z92.3 Personal history of irradiation
0.594 0.406 0.000
N23 Unspecified renal colic
0.593 0.407 0.000
C60-C63 Malignant neoplasms of male genital organs
0.592 0.408 0.000
Z87.8 Personal history of other specified conditions
0.591 0.409 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.591 0.409 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.591 0.409 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.591 0.409 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.591 0.409 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.589 0.411 0.000
B95-B98 Bacterial, viral and other infectious agents
0.588 0.412 0.000
Z42 Follow-up care involving plastic surgery
0.588 0.412 0.000
A08 Viral and other specified intestinal infections
0.587 0.413 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.585 0.414 0.000
N50 Other disorders of male genital organs
0.585 0.414 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.585 0.414 0.000
N48 Other disorders of penis
0.585 0.414 0.000
N45 Orchitis and epididymitis
0.585 0.414 0.000
N43 Hydrocele and spermatocele
0.585 0.414 0.000
N42 Other disorders of prostate
0.585 0.414 0.000
N41 Inflammatory diseases of prostate
0.585 0.414 0.000
N46 Male infertility
0.585 0.414 0.000
N44 Torsion of testis
0.585 0.414 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.585 0.415 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.585 0.415 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.585 0.415 0.000
C56 Malignant neoplasm of ovary
0.583 0.417 0.000
H40-H42 Glaucoma
0.582 0.418 0.000
M20 Acquired deformities of fingers and toes
0.581 0.419 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.580 0.420 0.000
N21 Calculus of lower urinary tract
0.580 0.420 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.580 0.420 0.000
H25-H28 Disorders of lens
0.580 0.420 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.579 0.421 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.579 0.421 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.579 0.421 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.578 0.422 0.000
Z92.9 Personal history of medical treatment, unspecified
0.578 0.422 0.000
Z92.8 Personal history of other medical treatment
0.578 0.422 0.000
Z92.5 Personal history of rehabilitation measures
0.578 0.422 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.578 0.422 0.000
Z92.0 Personal history of contraception
0.578 0.422 0.000
N40 Hyperplasia of prostate
0.574 0.426 0.000
K63 Other diseases of intestine
0.573 0.427 0.000
N37 Urethral disorders in diseases classified elsewhere
0.572 0.428 0.000
N36 Other disorders of urethra
0.572 0.428 0.000
N34 Urethritis and urethral syndrome
0.572 0.428 0.000
N33 Bladder disorders in diseases classified elsewhere
0.572 0.428 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.572 0.428 0.000
A04 Other bacterial intestinal infections
0.570 0.429 0.000
M80-M85 Disorders of bone density and structure
0.570 0.430 0.000
H55-H59 Other disorders of eye and adnexa
0.570 0.430 0.000
H53-H54 Visual disturbances and blindness
0.570 0.430 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.570 0.430 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.570 0.430 0.000
H43-H45 Disorders of vitreous body and globe
0.570 0.430 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.570 0.430 0.000
H10-H13 Disorders of conjunctiva
0.570 0.430 0.000
R56.8 Other and unspecified convulsions
0.569 0.431 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.568 0.431 0.000
F99-F99 Unspecified mental disorder
0.567 0.433 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.567 0.433 0.000
F80-F89 Disorders of psychological development
0.567 0.433 0.000
F70-F79 Mental retardation
0.567 0.433 0.000
F60-F69 Disorders of adult personality and behaviour
0.567 0.433 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.567 0.433 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.567 0.433 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.567 0.433 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.566 0.434 0.000
N03 Chronic nephritic syndrome
0.564 0.436 0.000
E50-E64 Other nutritional deficiencies
0.564 0.436 0.000
E40-E46 Malnutrition
0.564 0.436 0.000
E20-E35 Disorders of other endocrine glands
0.564 0.436 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.564 0.436 0.000
C50-C50 Malignant neoplasm of breast
0.563 0.437 0.000
J22 Unspecified acute lower respiratory infection
0.562 0.438 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.562 0.438 0.000
M13 Other arthritis
0.562 0.438 0.000
M70-M79 Other soft tissue disorders
0.561 0.439 0.000
C78.0 Secondary malignant neoplasm of lung
0.559 0.440 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.559 0.440 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.559 0.441 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.559 0.441 0.000
R63.5 Abnormal weight gain
0.559 0.441 0.000
R63.3 Feeding difficulties and mismanagement
0.559 0.441 0.000
R63.2 Polyphagia
0.559 0.441 0.000
R63.1 Polydipsia
0.559 0.441 0.000
Z76 Persons encountering health services in other circumstances
0.558 0.442 0.000
Z75 Problems related to medical facilities and other health care
0.558 0.442 0.000
Z74 Problems related to care-provider dependency
0.558 0.442 0.000
Z73 Problems related to life-management difficulty
0.558 0.442 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.558 0.442 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.558 0.442 0.000
I84.1 Internal haemorrhoids with other complications
0.558 0.442 0.000
Z54 Convalescence
0.556 0.443 0.000
Z52 Donors of organs and tissues
0.556 0.443 0.000
Z49 Care involving dialysis
0.556 0.443 0.000
Z48 Other surgical follow-up care
0.556 0.443 0.000
Z44 Fitting and adjustment of external prosthetic device
0.556 0.443 0.000
Z43 Attention to artificial openings
0.556 0.443 0.000
Z41 Procedures for purposes other than remedying health state
0.556 0.443 0.000
Z40 Prophylactic surgery
0.556 0.443 0.000
I84.6 Residual haemorrhoidal skin tags
0.556 0.444 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.555 0.445 0.000
J30-J39 Other diseases of upper respiratory tract
0.554 0.446 0.000
N84 Polyp of female genital tract
0.552 0.447 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.549 0.450 0.000
G20-G26 Extrapyramidal and movement disorders
0.546 0.454 0.000
K50-K52 Noninfective enteritis and colitis
0.546 0.454 0.000
K90-K93 Other diseases of the digestive system
0.546 0.454 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.543 0.456 0.000
F30-F39 Mood [affective] disorders
0.543 0.457 0.000
R31 Unspecified haematuria
0.543 0.457 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.540 0.460 0.000
R47 Speech disturbances, not elsewhere classified
0.540 0.460 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.539 0.461 0.000
L50-L54 Urticaria and erythema
0.539 0.461 0.000
L40-L45 Papulosquamous disorders
0.539 0.461 0.000
L20-L30 Dermatitis and eczema
0.539 0.461 0.000
L10-L14 Bullous disorders
0.539 0.461 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.539 0.461 0.000
I63 Cerebral infarction
0.538 0.462 0.000
S89 Other and unspecified injuries of lower leg
0.537 0.463 0.000
S88 Traumatic amputation of lower leg
0.537 0.463 0.000
S87 Crushing injury of lower leg
0.537 0.463 0.000
S86 Injury of muscle and tendon at lower leg level
0.537 0.463 0.000
S85 Injury of blood vessels at lower leg level
0.537 0.463 0.000
S84 Injury of nerves at lower leg level
0.537 0.463 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.537 0.463 0.000
S81 Open wound of lower leg
0.537 0.463 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.535 0.465 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.534 0.466 0.000
N30.9 Cystitis, unspecified
0.533 0.467 0.000
Z72.0 Tobacco use
0.533 0.467 0.000
Z45.2 Adjustment and management of vascular access device
0.532 0.468 0.000
C80 Malignant neoplasm without specification of site
0.532 0.468 0.000
C79 Secondary malignant neoplasm of other sites
0.532 0.468 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.532 0.468 0.000
N35 Urethral stricture
0.531 0.469 0.000
Z90.7 Acquired absence of genital organ(s)
0.531 0.469 0.000
I69 Sequelae of cerebrovascular disease
0.531 0.469 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.531 0.469 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.531 0.469 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.531 0.469 0.000
I62 Other nontraumatic intracranial haemorrhage
0.531 0.469 0.000
I61 Intracerebral haemorrhage
0.531 0.469 0.000
I60 Subarachnoid haemorrhage
0.531 0.469 0.000
Z91.5 Personal history of self-harm
0.531 0.469 0.000
J17 Pneumonia in diseases classified elsewhere
0.531 0.469 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.531 0.469 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.531 0.469 0.000
J12 Viral pneumonia, not elsewhere classified
0.531 0.469 0.000
J11 Influenza, virus not identified
0.531 0.469 0.000
J10 Influenza due to identified influenza virus
0.531 0.469 0.000
J14 Pneumonia due to Haemophilus influenzae
0.531 0.469 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.531 0.469 0.000
J09 Influenza due to certain identified influenza virus
0.531 0.469 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.529 0.471 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.529 0.471 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.529 0.471 0.000
Z03.3 Observation for suspected nervous system disorder
0.529 0.471 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.529 0.471 0.000
Z03.1 Observation for suspected malignant neoplasm
0.529 0.471 0.000
Z03.0 Observation for suspected tuberculosis
0.529 0.471 0.000
J43.8 Other emphysema
0.529 0.471 0.000
J43.2 Centrilobular emphysema
0.529 0.471 0.000
J43.1 Panlobular emphysema
0.529 0.471 0.000
J43.0 MacLeod's syndrome
0.529 0.471 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.529 0.471 0.000
Z50 Care involving use of rehabilitation procedures
0.529 0.471 0.000
K35-K38 Diseases of appendix
0.528 0.472 0.000
C78.7 Secondary malignant neoplasm of liver
0.528 0.472 0.000
A41 Other septicaemia
0.527 0.473 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.527 0.473 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.526 0.473 0.000
R21 Rash and other nonspecific skin eruption
0.525 0.475 0.000
N13 Obstructive and reflux uropathy
0.525 0.475 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.525 0.475 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.525 0.475 0.000
N06 Isolated proteinuria with specified morphological lesion
0.525 0.475 0.000
N05 Unspecified nephritic syndrome
0.525 0.475 0.000
N04 Nephrotic syndrome
0.525 0.475 0.000
N02 Recurrent and persistent haematuria
0.525 0.475 0.000
N01 Rapidly progressive nephritic syndrome
0.525 0.475 0.000
N00 Acute nephritic syndrome
0.525 0.475 0.000
R13 Dysphagia
0.525 0.475 0.000
K70-K77 Diseases of liver
0.524 0.476 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.523 0.477 0.000
A07 Other protozoal intestinal diseases
0.522 0.477 0.000
A06 Amoebiasis
0.522 0.477 0.000
A05 Other bacterial foodborne intoxications
0.522 0.477 0.000
A03 Shigellosis
0.522 0.477 0.000
A02 Other Salmonella infections
0.522 0.477 0.000
A01 Typhoid and paratyphoid fevers
0.522 0.477 0.000
A00 Cholera
0.522 0.477 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.522 0.478 0.000
R20 Disturbances of skin sensation
0.522 0.478 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.522 0.478 0.000
J04 Acute laryngitis and tracheitis
0.522 0.478 0.000
J03 Acute tonsillitis
0.522 0.478 0.000
J02 Acute pharyngitis
0.522 0.478 0.000
J01 Acute sinusitis
0.522 0.478 0.000
J00 Acute nasopharyngitis [common cold]
0.522 0.478 0.000
J18.9 Pneumonia, unspecified
0.522 0.478 0.000
K63.5 Polyp of colon
0.520 0.480 0.000
N17.8 Other acute renal failure
0.519 0.480 0.000
N17.2 Acute renal failure with medullary necrosis
0.519 0.480 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.519 0.480 0.000
N17.0 Acute renal failure with tubular necrosis
0.519 0.480 0.000
M23 Internal derangement of knee
0.519 0.481 0.000
M15-M19 Arthrosis
0.519 0.481 0.000
E86 Volume depletion
0.519 0.481 0.000
K65-K67 Diseases of peritoneum
0.518 0.482 0.000
O47 False labour
0.518 0.482 0.000
R87 Abnormal findings in specimens from female genital organs
0.517 0.483 0.000
N80 Endometriosis
0.517 0.483 0.000
D80-D89 Certain disorders involving the immune mechanism
0.516 0.484 0.000
D55-D59 Haemolytic anaemias
0.516 0.484 0.000
Z30 Contraceptive management
0.515 0.484 0.000
F10.1 Harmful use
0.516 0.484 0.000
N95 Menopausal and other perimenopausal disorders
0.515 0.484 0.000
S00 Superficial injury of head
0.515 0.484 0.000
Z86.7 Personal history of diseases of the circulatory system
0.515 0.484 0.000
J21 Acute bronchiolitis
0.515 0.485 0.000
J20 Acute bronchitis
0.515 0.485 0.000
Z03.4 Observation for suspected myocardial infarction
0.514 0.486 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.514 0.486 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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